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A Modern-Day Algorithm for the Treatment of Multi-Ligament Knee Injuries 治疗膝关节多韧带损伤的现代算法
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-14 DOI: 10.1007/s43465-024-01252-x
Fidelius von Rehlingen-Prinz, Sebastian Rilk, Victor Beckers, Robert O’Brien, Gregory S. DiFelice

Introduction

Multiligament knee injuries (MLKI) are rare and complex, significantly impacting long-term outcomes, with risks of osteoarthritis, joint stiffness, and reduced activity levels.

Objective

To explore the evolution of MLKI treatment protocols, comparing historical and modern approaches, and to present a patient-tailored, preservation-first algorithm.

Methods

This article reviews the literature on MLKI management, focusing on surgical timing, techniques, and rehabilitation protocols. The proposed algorithm categorizes MLKIs based on tear location and tissue quality, incorporating options, such as primary ligament repair, augmentation, and reconstruction.

Results

The modern preservation-first algorithm provides a tailored approach to MLKI treatment, addressing the complexity and heterogeneity of these injuries, and aims to mitigate risks like postoperative arthrofibrosis.

Conclusion

MLKI management remains complex and controversial. The presented algorithm offers a structured, individualized treatment strategy that integrates modern surgical and rehabilitation advancements.

导言膝关节多韧带损伤(MLKI)是一种罕见而复杂的损伤,对长期预后有重大影响,可能导致骨关节炎、关节僵硬和活动能力下降。方法本文回顾了有关 MLKI 治疗的文献,重点关注手术时机、技术和康复方案。结果现代的 "保护优先 "算法为 MLKI 治疗提供了一种量身定制的方法,解决了这些损伤的复杂性和异质性,旨在降低术后关节纤维化等风险。本文介绍的算法提供了一种结构化、个性化的治疗策略,融合了现代外科手术和康复治疗的进步。
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引用次数: 0
Mini-LET: A Technique Note 迷你 LET:技术说明
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-14 DOI: 10.1007/s43465-024-01269-2
Manit Arora, Tapish Shukla, Jay Shah

Lateral extra-articular tenodesis (LET) has shown an upswing in popularity since the role of antero-lateral rotatory instability (ALRI) in ACL tears has become better understood. Its primary aim is to restore antero-lateral rotatory stability and hence reduce stresses placed on the ACL graft in high-risk individuals which should reduce graft failure rates. Many techniques have been described for LET using a variety of fixation methods (screws, anchors, etc.). Most of these techniques rely on a large incision laterally. We describe a novel technique (‘mini-LET’) which uses a 3–4 cm incision, to improve cosmesis.

随着人们对前交叉韧带撕裂的前外侧旋转不稳定性(ALRI)的作用有了更深入的了解,外侧关节外腱鞘置换术(LET)越来越受欢迎。其主要目的是恢复前外侧旋转稳定性,从而减少前交叉韧带移植对高危人群的压力,降低移植失败率。目前已介绍了许多使用各种固定方法(螺钉、锚等)进行 LET 的技术。这些技术中的大多数都依赖于侧面的大切口。我们介绍了一种新型技术("迷你 LET"),该技术使用 3-4 厘米的切口,以改善外观。
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引用次数: 0
The Use of Nitinol Continuous Compression Implants in Orthopaedic Trauma 镍钛诺连续加压植入物在创伤骨科中的应用
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-14 DOI: 10.1007/s43465-024-01253-w
Dylan Mistry, Usama Rahman, Chetan Khatri, William Carlos, Alastair Stephens, Bryan Riemer, Jayne Ward

Background

Continuous compression implants (CCIs) can provide continuous compression across a fracture site. They are mainly used in foot/ankle surgery, with very limited descriptions in the literature of their potential for trauma. The aim of this study was to describe the use and associated outcomes of CCIs in modern day trauma practice.

Methods

This was a single-centred case series with a retrospective analysis of a prospectively maintained database of any patients who were treated with a CCI across 4 years. The primary outcome was to determine the mode of the CCIs and secondary outcomes were unplanned returns to theatre.

Results

60 patients were eligible with a mean age of 44.2 and 122 CCIs were used. 51 patients were treated for acute fractures, 9 were treated for non-unions, and 27 patients had open injuries. 42 of the 122 CCIs were used as definitive fixation (midfoot dislocations, an iliac wing fixation and isolated medial malleolus fixation), and the rest as adjuncts for fixation; of this remainder, 39 were used in reduction mode, 38 for fixation of key fragments, and 3 for compression. Ten patients returned to theatre, two for metalwork failure, two for infection and 6 for non-unions—three were acute fractures and three originally non-unions.

Conclusion

This paper demonstrates a novel technique for the use of CCIs in UK trauma practice as either definitive fixations or in three different modes as adjuncts to fixation. They do not replace tradition implants but do have equivalent rates of complications. They may be a useful tool in the arsenal for trauma surgeons.

背景连续加压植入物(CCIs)可对骨折部位进行连续加压。它们主要用于足部/踝部手术,有关其创伤应用潜力的文献描述非常有限。本研究旨在描述CCIs在现代创伤实践中的使用情况和相关结果。方法这是一项单中心病例系列研究,通过对前瞻性维护的数据库进行回顾性分析,该数据库收录了4年内接受过CCI治疗的所有患者。结果60名患者符合条件,平均年龄为44.2岁,共使用了122次CCI。51名患者接受了急性骨折治疗,9名患者接受了非骨折治疗,27名患者为开放性损伤。122枚CCI中有42枚用于最终固定(足中部脱位、髂骨翼固定和孤立的内侧踝骨固定),其余的用于辅助固定;在其余的CCI中,39枚用于还原模式,38枚用于固定关键碎片,3枚用于加压。10 名患者返回手术室,其中 2 人因金属制品失效,2 人因感染,6 人因不愈合--3 人是急性骨折,3 人最初是不愈合。 结论 本文展示了在英国创伤实践中使用 CCIs 作为最终固定物或以三种不同模式作为辅助固定物的新技术。它们不能取代传统的植入物,但并发症发生率相当。它们可能是创伤外科医生的有用工具。
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引用次数: 0
Combined AMRI and ALRI of the Knee in Elite Kabaddi Players: A Prospective Cohort Study of 26 Players 卡巴迪精英运动员膝关节的联合 AMRI 和 ALRI:对 26 名球员的前瞻性队列研究
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-13 DOI: 10.1007/s43465-024-01268-3
Manit Arora, Ananya Sharma, Tapish Shukla, Jay Shah

Introduction

ACL tears are the most common injuries in kabaddi, an inherently violent high pivoting and high-velocity direct contact sport. Combined ACL and MCL injuries and combined ACL and ALL injuries have been better understood but there is a lacuna of literature on these combined injuries in kabaddi players and no literature on combined AMRI and ALRI injuries. The present prospective cohort study aims to assess knee outcomes and return to sport for these injuries in elite kabaddi players.

Methods

A prospective cohort of 26 elite kabaddi players with clinical and MRI findings of ACL and MCL high-grade partial or complete tears were recruited. After ACL reconstruction and MCL repair, the resultant pivot shift was assessed against the now intact medial pillar and those with high-grade or explosive pivot were addressed using a modified deep Lemaire lateral extra-articular tenodesis. Pain scores (VAS) and knee outcomes (IKDC and Lysholm scores) were assessed pre-operatively and at regular intervals until 1-year follow-up. Return to sport and complications were also assessed.

Results

There was significant improvement in pain and knee scores throughout the study period, with most patients achieving full scores by six months duration. Return to sport was 96% and return to sport at pre-injury level was 77%. Complication rate of the combined triple procedure was low (< 5%), with most complications being minor.

Conclusion

The triple procedure of ACL reconstruction, MCL repair and Lateral extraarticular tenodesis successfully addressed the combined AMRI and ALRI in elite kabaddi players with a high rate of return to sport, excellent knee outcomes and low complication rate.

前交叉韧带撕裂是卡巴迪运动中最常见的损伤,而卡巴迪运动本身就是一项暴力的高旋转和高速直接接触运动。前交叉韧带和前交叉韧带联合损伤以及前交叉韧带和前交叉韧带联合损伤已得到较好的理解,但有关卡巴迪运动员这些联合损伤的文献却很缺乏,也没有有关 AMRI 和 ALRI 联合损伤的文献。本前瞻性队列研究旨在评估卡巴迪精英球员膝关节损伤的预后和运动恢复情况。方法招募了 26 名临床和 MRI 检查发现前交叉韧带和 MCL 高级别部分或完全撕裂的卡巴迪精英球员组成前瞻性队列。在前交叉韧带重建和 MCL 修复后,针对现在完好的内侧支柱评估了由此产生的枢轴移位,并使用改良的深 Lemaire 外侧关节外腱鞘修补术处理了那些有高等级或爆炸性枢轴移位的运动员。对疼痛评分(VAS)和膝关节效果(IKDC 和 Lysholm 评分)进行术前评估,并定期进行评估,直至随访 1 年。结果在整个研究期间,疼痛和膝关节评分均有明显改善,大多数患者在六个月后达到满分。恢复运动的比例为 96%,恢复到受伤前水平的比例为 77%。结论前交叉韧带重建术、MCL修复术和外侧关节外腱鞘切除术的三重手术成功解决了卡巴迪精英运动员的AMRI和ALRI问题,患者恢复运动的比例高,膝关节恢复良好,并发症发生率低。
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引用次数: 0
Lower Limb Length and Body Weight are Surrogate Predictors of Peroneus Longus Autograft Diameter 下肢长度和体重是腓肠肌自体移植物直径的替代预测指标
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-11 DOI: 10.1007/s43465-024-01266-5
Manit Arora, Sachin Tapasvi, Tapish Shukla, Chiranjeev Jani

Introduction

Graft diameters are essential in any ACL surgery, with diameters less than 8mm associated with higher revision rates. Peroneus longus (PL) grafts have garnered much attention recently due to ease of harvest and more reliable graft diameters. The present study aimed to study various anthropometric parameters associated with PL-graft diameters.

Methods

We performed a prospective cohort study of 50 patients undergoing PL harvest for ACL surgery at a tertiary referral hospital. Age, gender, height, weight, length of the lower leg (lateral tibial plateau to the tip of the fibula), circumference at the head of the fibula and girth at the lateral malleolus were measured pre-operatively. The length of the graft doubled and tripled graft diameters were assessed intra-operatively. Pearson correlation coefficient was used to study the association between the pre-operative anthropometric variables and the intra-operative graft diameters and length of graft harvested.

Results

The mean doubled and tripled PL-graft diameter in our study population was 7.7 ± 0.9 mm and 8.7 ± 0.8 mm, respectively. The mean length of the graft was 25.9 ± 3.5 cm. We found no significant correlation between graft diameters and age, gender or height of the patient. We found that the patient's weight significantly correlated (p < 0.001) with graft diameter. We also found that the length of the lower leg (p < 0.0001), circumference at the head of the fibula (p = 0.001) and girth at the lateral malleolus (p = 0.029) showed significant correlation with tripled PL-graft diameter.

Conclusion

We found that weight, length of the lower leg and girth at the head of the fibula showed a strong correlation with tripled PL-graft diameter.

导言:移植物直径对任何前交叉韧带手术都至关重要,直径小于 8 毫米的移植物翻修率较高。由于腓肠肌(Pleoneus longus,PL)移植物易于采集且移植物直径更可靠,因此近来备受关注。本研究旨在研究与腓骨长肌移植物直径相关的各种人体测量参数。方法我们在一家三级转诊医院对50名接受腓骨长肌移植物移植的前交叉韧带手术患者进行了前瞻性队列研究。术前测量了患者的年龄、性别、身高、体重、小腿长度(胫骨外侧平台至腓骨尖)、腓骨头周长和外侧踝骨周长。术中评估了两倍和三倍移植物直径的长度。皮尔逊相关系数用于研究术前人体测量变量与术中移植物直径和移植物收获长度之间的关系。结果我们的研究对象中,PL-移植物的平均两倍和三倍直径分别为 7.7 ± 0.9 毫米和 8.7 ± 0.8 毫米。移植物的平均长度为 25.9 ± 3.5 厘米。我们发现移植物直径与患者的年龄、性别或身高之间没有明显的相关性。我们发现患者的体重与移植物直径有明显的相关性(p <0.001)。我们还发现,小腿的长度(p <0.0001)、腓骨头的周长(p = 0.001)和外侧踝骨的周长(p = 0.029)与三倍 PL 移植物直径呈显著相关。
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引用次数: 0
Atypical Hydatid Cyst of Entire Right Femur with Pathological Fracture: Total Femur Replacement Case Report 右股骨全段非典型水囊伴病理性骨折:全股骨置换术病例报告
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-11 DOI: 10.1007/s43465-024-01226-z
Hemant Sharma, Lokesh Garg, Rajesh Kumar Verma, Asgar Ali, Lovesh Agarwal, Guruditta Khurana, Lalit Kumar, Sourabh Chachan, Jasmine Kokiloo, Nikita Jajodia

Introduction

Hydatid disease is uncommon in Humans. It rarely affects the bones and joints (0.5–4%). Frequent sites of bony involvement are vertebrae, pelvic bones, upper end of long bones e.g. humerus, femur and tibia.

Material and methods

We report a case of 41-year old female with primary Hydatid cyst of the entire right femur. Patient complaint of severe pain and was non ambulatory since the last 2 months.

Results

Here, single staged Total Right Femur Replacement was done under General Anaesthesia. Patient was discharged after 6 days of hospital stay in a stable condition where physical rehabilitation was initiated after day one of the surgery, progressing to aided walking, standing and active lower limb exercises.

Conclusion

Involvement of the entire femur was a challenging case. There is no consensus/gold standard treatment of severe cases. Given the involvement of the entire Right Femur along with spillage in the neighbouring muscles, patient underwent Total Femur Replacement with Hip and Knee Replacement.

导言水肿病在人类中并不常见。它很少影响骨骼和关节(0.5-4%)。常见的骨骼受累部位是椎骨、盆骨、长骨上端,如肱骨、股骨和胫骨。患者主诉剧烈疼痛,且在过去两个月中一直无法行走。结果在全身麻醉下,患者接受了分阶段的右股骨全置换术。住院 6 天后,患者病情稳定出院,术后第一天开始进行身体康复训练,逐渐发展到辅助行走、站立和主动下肢锻炼。对于严重病例的治疗,目前还没有共识/金标准。鉴于整个右股骨受累,同时邻近肌肉也受到影响,患者接受了全股骨置换术和髋关节、膝关节置换术。
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引用次数: 0
Patient Morbidity due to Sterile Zone Fire Outbreak during an Orthopaedic Trauma Surgery: A Case Report 创伤骨科手术中无菌区起火导致的患者发病率:病例报告
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-11 DOI: 10.1007/s43465-024-01264-7
Nishit Palo, Mahima Lakhanpal, Madhan Jeyaraman, Abhishek Shukla

Operating room fires are considered ‘never events’; they are uncommon but can prove to be potentially damaging to the humans involved and the expensive operating room instrumentation. Research indicates that significant knowledge gaps exist in orthopaedic community relating to fire prevention, fire safety and fire management. A 24-year-old male patient with clavicle fracture was planned for surgical fixation. A nerve block procedure was performed. Skin preparation was done with 10% betadine scrub and surgical spirit. The surgical team performed skin incision, and superficial dissection was carried out using electrocautery. A fire broke out, and on noticing the fumes, saline was poured, drapes were removed and the authors observed charring of deeper linen and skin damage. A superficial thermal burn, greenish blue in colour (7 x 1.5 cms) located 1–1.5 cms above the surgical incision was evident (see Fig. 4). The event was later explained to the patient. The surgical scar was healthy, and burn margins became defined and darkish green blue. Dressing was done with megaheal ointment. The burn healed in 4 weeks. As these events are rare, a specific action protocol has not been orchestrated. With newer reports coming in, orthopaedic associations should work out a sustainable plan of action to minimize the occurrence of these events and the damage incurred. Training of orthopaedic and anaesthesia team and operating room personnel remains the most important step in countering a fire event, as more the helping hands, the better is the outcome. Maintaining a high vigil ensures timely action response to maintain patient safety and counter adverse events effectively.

手术室火灾被认为是 "从未发生过的事件",虽然并不常见,但可能会对相关人员和昂贵的手术室仪器造成潜在损害。研究表明,骨科界在防火、消防安全和消防管理方面存在很大的知识差距。一名 24 岁男性患者锁骨骨折,计划进行手术固定。进行了神经阻滞手术。使用 10%倍他丁擦洗剂和手术灵进行了皮肤准备。手术团队进行了皮肤切口,并使用电烧进行了表皮剥离。一场大火发生了,在注意到烟雾后,人们倒入了生理盐水,移开了帘布,作者观察到深层亚麻布被烧焦,皮肤受损。在手术切口上方 1-1.5 厘米处有明显的表皮热烧伤,呈青绿色(7 x 1.5 厘米)(见图 4)。后来向患者解释了这一事件。手术疤痕是健康的,烧伤边缘变得清晰,呈深绿色。医生使用大面积愈合膏进行了包扎。烧伤在 4 周后愈合。由于此类事件非常罕见,因此尚未制定具体的行动方案。随着新报告的不断出现,骨科协会应制定可持续的行动计划,尽量减少此类事件的发生和造成的损害。骨科和麻醉团队以及手术室人员的培训仍然是应对火灾事件的最重要步骤,因为帮助的人越多,结果就越好。保持高度警惕可确保及时采取应对措施,以维护患者安全和有效应对不良事件。
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引用次数: 0
Deep Learning for Automatic Knee Osteoarthritis Severity Grading and Classification 深度学习用于膝骨关节炎严重程度的自动分级和分类
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-11 DOI: 10.1007/s43465-024-01259-4
Shakti Kinger

Introduction

Knee osteoarthritis (OA) is a prevalent condition that significantly impacts the quality of life, often leading to the need for knee replacement surgery. Accurate and timely identification of knee degeneration is crucial for effective treatment and management. Traditional methods of diagnosing OA rely heavily on radiological assessments, which can be time-consuming and subjective. This study aims to address these challenges by developing a deep learning-based method to predict the likelihood of knee replacement and the Kellgren–Lawrence (KL) grade of knee OA from X-ray images.

Methodology

We employed the Osteoarthritis Initiative (OAI) dataset and utilized a transfer learning approach with the Inception V3 architecture to enhance the accuracy of OA detection. Our approach involved training 14 different models—Xception, VGG16, VGG19, ResNet50, ResNet101, ResNet152, ResNet50V2, ResNet101V2, ResNet152V2, Inception V3, Inception, ResNetV2, DenseNet121, DenseNet169, DenseNet201—and comparing their performance.

Results

The study incorporated pixel ratio computation and picture pre-processing, alongside a decision tree model for prediction. Our experiments revealed that the Inception V3 model achieved the highest training accuracy of 91% and testing accuracy of 67%, with notable performance in both training and validation phases. This model effectively identified the presence and severity of OA, correlating with the Kellgren–Lawrence scale and facilitating the assessment of knee replacement needs.

Conclusion

By integrating advanced deep learning techniques with radiological diagnostics, our methodology supports radiologists in making more accurate and prompt decisions regarding knee degeneration. The Inception V3 model stands out as the optimal choice for knee X-ray analysis, contributing to more efficient and timely healthcare delivery for patients with knee osteoarthritis.

导言:膝关节骨性关节炎(OA)是一种普遍存在的疾病,严重影响患者的生活质量,往往需要进行膝关节置换手术。准确、及时地识别膝关节退行性病变对有效治疗和管理至关重要。传统的 OA 诊断方法在很大程度上依赖于放射学评估,而放射学评估可能既耗时又主观。本研究旨在通过开发一种基于深度学习的方法来预测膝关节置换的可能性,并根据 X 光图像预测膝关节 OA 的 Kellgren-Lawrence (KL) 等级,从而应对这些挑战。我们的方法包括训练 14 种不同的模型:Xception、VGG16、VGG19、ResNet50、ResNet101、ResNet152、ResNet50V2、ResNet101V2、ResNet152V2、Inception V3、Inception、ResNetV2、DenseNet121、DenseNet169、DenseNet201,并比较它们的性能。实验结果表明,Inception V3 模型的训练准确率最高,达到 91%,测试准确率最高,达到 67%,在训练和验证阶段均表现突出。通过将先进的深度学习技术与放射诊断技术相结合,我们的方法支持放射科医生就膝关节退化做出更准确、更迅速的决定。Inception V3 模型是膝关节 X 射线分析的最佳选择,有助于为膝关节骨关节炎患者提供更高效、更及时的医疗服务。
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引用次数: 0
Use of Internal Bracing in Multi-ligamentous Knee Injury Reconstruction: A Systematic Review 在多韧带膝关节损伤重建中使用内支撑:系统回顾
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-11 DOI: 10.1007/s43465-024-01260-x
Abbie Randall, Richard Pearse, Shahnawaz Khan, Henry Atkinson

Background

Multi-ligament Knee Injuries (MLKI) are often caused by a high-energy impact resulting in dislocation of the knee joint. Given the higher degree of instability associated with these MLKIs, surgical fixation with adjunctive internal bracing and the use of suture augmentation have been proposed with the intention of better restoring knee stability and improving the long-term outcomes of surgery. This systematic review seeks to appraise the current literature in relation to the role of internal bracing in the management of MLKI.

Methods

All randomised control trials, observational studies, cohort studies, and cross-sectional studies containing patients with multi-ligamentous knee injuries managed with the use of internal bracing or suture tape augmentation were included in this review. The primary outcomes of interest were re-operation and failure rates, with secondary outcomes focussed on patient-reported outcome measures (PROMs) and examination findings of knee stability.

Results

282 studies were identified for screening, 13 of which were suitable for inclusion and five of these had injuries with Schenck grade III or above. Of the studies identified, failure rates ranged from 0 to 13.6%. Lysholm score was the most commonly utilised PROM tool with scores ranging from 61.8 to 95. Stiffness requiring MUA ± adhesiolysis was a common complication identified across studies.

Conclusions

The use of internal bracing in Multi-ligament Knee Injuries appears to be as effective as not using an internal bracing technique. The post-operative PROMs and relatively low failure rates reflect promising outcomes for the ongoing use of internal bracing in MLKI. However, further prospective studies directly comparing braced versus non-braced ligamentous repairs are required in order to definitively determine if the use of the internal brace does allow for increased joint stability and early rehabilitation.

背景膝关节多韧带损伤(MLKI)通常是由高能量撞击导致膝关节脱位引起的。鉴于这些膝关节多韧带损伤具有较高的不稳定性,人们提出了手术固定并辅以内支撑和缝合增量的方法,以期更好地恢复膝关节的稳定性并改善手术的长期疗效。本系统性综述旨在评估目前与内支架在多韧带膝关节损伤治疗中的作用相关的文献。方法本综述纳入了所有随机对照试验、观察性研究、队列研究和横断面研究,这些研究都包含了使用内支架或缝合带增量术治疗的多韧带膝关节损伤患者。研究的主要结果是再次手术率和失败率,次要结果是患者报告的结果测量(PROMs)和膝关节稳定性的检查结果。结果 筛选出282项研究,其中13项适合纳入,其中5项的损伤程度为申克III级或以上。在确定的研究中,失败率从 0% 到 13.6% 不等。Lysholm 评分是最常用的 PROM 工具,评分范围从 61.8 到 95 分不等。结论在多韧带膝关节损伤中使用内固定似乎与不使用内固定技术一样有效。术后PROMs和相对较低的失败率反映出在多韧带膝关节损伤中持续使用内支撑技术具有良好的效果。不过,还需要进一步的前瞻性研究,直接比较有支撑与无支撑的韧带修复,以明确确定使用内支撑是否能增加关节稳定性和早期康复。
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引用次数: 0
Single/ Multiple Dose Percutaneously Injected LR-PRP Enhances Union Rate in Fracture Delayed Unions: A Prospective Case Series 单剂量/多剂量经皮注射 LR-PRP 提高骨折延迟联合的联合率:前瞻性病例系列
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-10 DOI: 10.1007/s43465-024-01265-6
Kishor Kunal, Nitesh Gahlot, Neeraj Choudhary, Abhay Elhence

Background

Average bone healing times of common fractures in adults ranges from 3 to 12 weeks and is location dependent. Platelet Rich Plasma (PRP) stimulates natural healing process through growth factors contained in platelets and has been employed for the same in delayed unions.

Methods

All patients > 18 years and documented delayed union were included in the study. Patients were followed up monthly after each Leucocyte-rich PRP (LR-PRP) injection and a decision for repeat PRP injection was taken on basis of visible impression in radiograph after previous injection.

Results

Total 36 patients were studied in which 5 patients were lost to follow-up. Union was achieved in 28/31 (90.3%). 20 (71.4%) patients required only single PRP injections. 4 (14.3%) patients required 2 PRP injections, 3 (10.7%) patients required 3 PRP injections and 1 (3.6%) patient required 4 PRP injection. There was no significant correlation of number of PRPs to time from 1st PRP-union or time from last PPR- union.

Conclusion

Single/multiple dose percutaneously administered LR-PRP can be used as a fruitful alternative to catalyze union in patients having delayed union irrespective of site of injury.

背景成人常见骨折的平均骨愈合时间为 3 至 12 周不等,且与地点有关。富血小板血浆(PRP)通过血小板中所含的生长因子刺激自然愈合过程,已被用于延迟接合。研究方法将所有年龄在 18 岁以下且有延迟结合记录的患者纳入研究范围。每次注射富含白细胞的 PRP(LR-PRP)后,每月对患者进行随访,并根据上次注射后的 X 光片上的可见印记决定是否再次注射 PRP。28/31(90.3%)例患者实现了骨结合。20例(71.4%)患者只需注射一次 PRP。4名(14.3%)患者需要注射 2 次 PRP,3 名(10.7%)患者需要注射 3 次 PRP,1 名(3.6%)患者需要注射 4 次 PRP。结论单剂量/多剂量经皮给药 LR-PRP 可作为一种有效的替代方法,用于催化迟发性骨结合患者的骨结合,无论其受伤部位如何。
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引用次数: 0
期刊
Indian Journal of Orthopaedics
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