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Women in Orthopaedics: Substance and Strength. 整形外科中的女性:物质与力量。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-16 eCollection Date: 2025-10-01 DOI: 10.1007/s43465-025-01558-4
Rujuta Mehta
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引用次数: 0
Correction: Single-Stage Revision for Treatment of Prosthetic Joint Infection in Total Hip Arthroplasty. 修正:全髋关节置换术中假关节感染的单期翻修治疗。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-16 eCollection Date: 2025-11-01 DOI: 10.1007/s43465-025-01513-3
H Humphries, W Wignadasan, A Fontalis, A Alsheddi, M Shaeir, F S Haddad

[This corrects the article DOI: 10.1007/s43465-025-01405-6.].

[这更正了文章DOI: 10.1007/s43465-025-01405-6.]。
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引用次数: 0
Combined Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction Using Hamstring Autografts: A Detailed Surgical Technique. 自体腿筋联合前交叉韧带和前外侧韧带重建:一种详细的手术技术。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-16 eCollection Date: 2026-02-01 DOI: 10.1007/s43465-025-01550-y
Kaushal Patel, Nirali Mehta

Persistent rotational instability, reported in 15-35% of isolated anterior cruciate ligament (ACL) reconstruction remains a significant cause of graft failure and impaired return to sports. This has led to an increased interest in supplementing ACL reconstruction with anterolateral ligament (ALL) reconstruction to address residual rotational laxity. ALL reconstruction may better restore rotational stability compared to traditional lateral extra-articular procedures. The patient is positioned supine with the knee flexed at 90°, and standard landmarks are identified. Semitendinosus and gracilis tendons are harvested via a small incision. A quadrupled semitendinosus graft reconstructs the ACL, while the gracilis tendon reconstructs the ALL. Femoral tunnels for ACL and ALL reconstruction share a common anatomical entry point proximal and posterior to the lateral epicondyle. Tibial tunnels for the ALL are created below Gerdy's tubercle. Graft fixation is achieved with a suture disc on both femoral and tibial sides, ensuring physiological tension in extension. Patients begin immediate weight-bearing and range-of-motion exercises within controlled limits. A progressive rehabilitation protocol facilitates return to sports, allowing pivoting activities after six months. Combined ACL and ALL reconstruction using autologous hamstring grafts offers a reproducible surgical option for addressing rotational knee instability. Anatomical graft placement and minimally invasive techniques may offer the potential for improved clinical outcomes, decreased graft failure rates, and enhanced patient return to pre-injury activity levels.

据报道,在15-35%的孤立前交叉韧带(ACL)重建中,持续旋转不稳定仍然是移植物失败和运动恢复受损的重要原因。这导致了对前外侧韧带(ALL)重建辅助ACL重建以解决残余旋转松弛的兴趣增加。与传统的外侧关节外手术相比,ALL重建可以更好地恢复旋转稳定性。患者仰卧位,膝关节屈曲90°,确定标准标志。半腱肌和股薄肌腱通过一个小切口切除。四重半腱肌移植重建前交叉韧带,股薄肌腱重建ALL。前交叉韧带和ALL重建的股骨隧道在外侧上髁近端和后端有一个共同的解剖切入点。ALL的胫骨隧道在Gerdy结节下方创建。植骨固定采用股骨和胫骨两侧的缝合盘,确保伸展时的生理张力。患者立即开始在可控范围内进行负重和活动范围练习。渐进式康复方案有助于恢复运动,允许在六个月后进行关键活动。自体腘绳肌腱联合ACL和ALL重建为解决旋转膝关节不稳定提供了一种可重复的手术选择。解剖移植物放置和微创技术可能提供改善临床结果的潜力,降低移植物失败率,并增强患者恢复到损伤前的活动水平。
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引用次数: 0
Harvesting the Peroneus Longus Does Not Lead to Peroneal Brevis Hypertrophy: Prospective Ultrasound-Based Study of 40 Patients. 采集腓骨长肌不会导致腓骨短肌肥大:40例患者的前瞻性超声研究。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-16 eCollection Date: 2026-02-01 DOI: 10.1007/s43465-025-01565-5
Manit Arora, Sachin Tapasvi, Jay Shah, Ravi Sahani, Abhishek Prasad

Purpose: Peroneus longus (PL) graft harvest has recently gained popularity for various ligament reconstruction surgeries. A recent systematic review shows it is a safe and reproducible technique with low morbidity of donor sites (1). The method for PL harvest routinely involves tenodesis of the PL stump to the peroneus brevis (PB); however, recent work has shown no impact on ankle functional outcomes with or without tenodesis. Harvesting of the PL should theoretically lead to a hypertrophy of the PB to compensate for its function. The purpose of the present study was to assess the effect of PL harvest on the PB.

Methods: Institutional ethics approval was obtained from the institutional ethics review board (January 2024). A total of 40 consecutive patients from January 2024 to February 2024 were included in the study: 20 patients in the no tenodesis group and 20 patients in the tenodesis group. Demographic variables (age, gender, and level of play) were recorded. Pre-operative American Orthopedic Foot and Ankle Society Score (AOFAS) and Functional Ankle Disability Index (FADI) scores were calculated for both groups and compared with post-operative scores at six weeks, three months, six months, and one-year follow-up. Ultrasound scan of bilateral ankle to assess PL and PB diameters was performed pre-operatively and tracked at three months, six months, and one year post-surgery.

Results: For the entire study population (n = 40), we found that AOFAS and FADI scores showed no significant difference at any interval. Age, gender, and level of play had no impact on ankle functional outcomes. Harvesting the PL did not significantly increase ipsilateral PB or contralateral PL diameter post-surgery. There was no significant difference between the tenodesis and no tenodesis groups regarding either PL or PB diameter at any time.

Conclusion: Tenodesis of the PL to the PB has been the standard procedure for harvesting PL grafts for various ligament surgeries. Recent work has shown that tenodesis or no tenodesis does not impact ankle functional outcomes. The present ultrasound-based study indicates that the PB does not hypertrophy to compensate for a harvested PL. Further, tenodesis or no tenodesis has no impact on either PB or PL diameters.

目的:腓骨长肌(PL)移植收获近年来在各种韧带重建手术中得到了广泛的应用。最近的一项系统综述显示,这是一种安全、可重复的技术,供体部位的发病率低(1)。腓骨短肌采集的常规方法包括将腓骨短肌残端固定在腓骨短肌(PB)上;然而,最近的研究表明,有或没有肌腱固定术对踝关节功能结果没有影响。从理论上讲,收获PL应该导致PB的肥大,以补偿其功能。本研究的目的是评价有机肥收获对PB的影响。方法:获得机构伦理审查委员会的机构伦理批准(2024年1月)。2024年1月至2024年2月共纳入40例患者,其中20例为不固定组,20例为固定组。统计变量(年龄、性别和游戏水平)被记录下来。计算两组患者术前美国骨科足踝社会评分(AOFAS)和踝关节功能残疾指数(FADI)评分,并在随访6周、3个月、6个月和1年时与术后评分进行比较。术前对双侧踝关节进行超声扫描,以评估其PL和PB直径,并在术后3个月、6个月和1年进行跟踪。结果:对于整个研究人群(n = 40),我们发现AOFAS和FADI评分在任何时间间隔内均无显著差异。年龄、性别和比赛水平对踝关节功能结果没有影响。手术后,切除左腹并没有显著增加同侧左腹或对侧左腹直径。在任何时间内,肌腱固定组和未肌腱固定组在PL或PB直径方面均无显著差异。结论:在各种韧带手术中,前韧带与前韧带的肌腱固定术已成为前韧带移植的标准方法。最近的研究表明,肌腱固定或不肌腱固定不会影响踝关节功能的结果。目前基于超声的研究表明,PB不会肥大来补偿收获的PL。此外,肌腱固定术或不固定术对PB或PL直径都没有影响。
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引用次数: 0
A Bibliometric Analysis of Complications in Arthroscopic ACL Reconstruction: Two Decades of Insights. 关节镜下ACL重建并发症的文献计量学分析:二十年的见解。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-15 eCollection Date: 2026-02-01 DOI: 10.1007/s43465-025-01543-x
Manish Raj, Sudarsan Behera, Pawan Kumar, Sukla Mondal, Anil Kumar Rana, Dipanjan Mishra

Introduction: Arthroscopic ACL reconstruction, a cornerstone in modern orthopedics, aims to restore knee stability while minimizing complications. Bibliometric analysis provides insights into research trends, influential contributors, and advancements in this field.

Materials and methods: A systematic analysis of 104 eligible articles on ACL reconstruction complications was conducted using the Web of Science database. Data, including titles, authors, and journals, were extracted. Bibliometric insights were generated using R software, while VOS viewer visualized bibliographic coupling, co-authorship networks, and keyword co-occurrence through interactive mapping techniques.

Results: Annual publications peaked in 2022, with the U.S. contributing 73 studies and fostering global collaborations. Arthroscopy: The Journal of Arthroscopic and Related Surgery emerged as the leading journal, with the highest H-index and G-index. Dr. Brian Forsythe was identified as the most prolific author. Key articles addressed complications such as infections. Co-citation and co-authorship analyses highlighted collaborative efforts among institutions, while keyword analysis revealed prominent research themes, including ACL reconstruction techniques, complication management, and outcomes.

Conclusion: This 20-year bibliometric review underscores global research trends in arthroscopic ACL reconstruction, with the U.S. leading in both publication volume and impact. Journals like Arthroscopy set benchmarks in the field, while emerging research focuses on improving outcomes, addressing complications, and refining patellar tendon graft techniques.

Supplementary information: The online version contains supplementary material available at 10.1007/s43465-025-01543-x.

关节镜下前交叉韧带重建是现代骨科的基石,旨在恢复膝关节稳定性,同时尽量减少并发症。文献计量分析提供了对该领域的研究趋势、有影响力的贡献者和进展的见解。材料和方法:使用Web of Science数据库对104篇符合条件的ACL重建并发症的文章进行系统分析。提取数据,包括标题、作者和期刊。使用R软件生成文献计量学见解,而VOS查看器通过交互式映射技术可视化书目耦合、合著网络和关键词共现。结果:年度出版物在2022年达到顶峰,美国贡献了73项研究并促进了全球合作。关节镜:《关节镜及相关外科杂志》(Journal of Arthroscopic and Related Surgery)成为领先期刊,其h指数和g指数最高。Brian Forsythe博士被认为是最多产的作者。关键文章讨论了感染等并发症。共引和合著分析突出了机构间的合作努力,而关键词分析揭示了突出的研究主题,包括ACL重建技术、并发症管理和结果。结论:这项20年的文献计量回顾强调了关节镜下ACL重建的全球研究趋势,美国在出版物数量和影响方面都处于领先地位。像《关节镜》这样的期刊为该领域设定了基准,而新兴的研究则侧重于改善结果、解决并发症和改进髌骨肌腱移植技术。补充信息:在线版本包含补充资料,下载地址为10.1007/s43465-025-01543-x。
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引用次数: 0
Quadriceps Tendon Graft Leads to Stronger Flexion and Weaker Extension of the Knee Than Hamstring Graft Post-ACLR: Systematic Review and Meta-Analysis. 在aclr后,股四头肌肌腱移植比腘绳肌腱移植导致膝关节更强的屈曲和更弱的伸展:系统回顾和荟萃分析。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-15 eCollection Date: 2025-12-01 DOI: 10.1007/s43465-025-01545-9
Brandon A Young, James C Dawahare, Edward Lee Major, Eva L Morrison, Cailan L Feingold, Eric H Lin, Joseph N Liu, Austin V Stone

Purpose: The optimal autograft for restoring knee strength and expediting return-to-sport following anterior cruciate ligament reconstruction (ACLR) remains debated. This systematic review and meta-analysis compared isokinetic strength and patient-reported outcomes after ACLR using quadriceps tendon (QT), hamstring tendon (HT), or bone-patellar tendon-bone (BTB) autografts to determine graft-specific recovery patterns.

Methods: PubMed, Cochrane Library, EMBASE, and Google Scholar were systematically searched for comparative studies evaluating isokinetic strength following primary ACLR using QT, HT, or BTB autografts. Non-English, unavailable full-text, animal/cadaveric, and physeal-sparing studies were excluded. MINORS and Detsky evaluated bias risk. Key findings were quantified, and subgroup meta-analyses were performed on limb symmetry index (LSI) values (significance: p < 0.05).

Results: Seventeen studies (1,705 patients: QT = 765, HT = 725, BTB = 215) with follow-ups through 48 months were included. Due to data heterogeneity, four to six studies qualified for each meta-analysis. Among 13 QT vs. HT studies, QT grafts demonstrated weaker extensor strength in nine (56.3%) and greater flexor strength in six (37.5%). No differences were reported in extensor or flexor strength in four (25.0%) and seven (43.8%) studies, respectively. For QT vs. BTB, two studies (12.5%) showed similar extensor strength, whereas two reported conflicting results. QT had greater flexor strength in one (6.3%) and similar strength in three (18.8%) studies. Postoperative pain was comparable between QT and HT.

Conclusions: QT autografts resulted in stronger flexion and weaker extension than HT autografts after ACLR. Tailored rehabilitation targeting graft-specific deficits may accelerate recovery. Further research is required to clarify outcomes between QT and BTB autografts.Level of evidence: IV.

目的:在前交叉韧带重建(ACLR)后恢复膝关节力量和加速恢复运动的最佳自体移植物仍然存在争议。本系统综述和荟萃分析比较了使用股四头肌肌腱(QT)、腘绳肌腱(HT)或骨-髌骨肌腱-骨(BTB)自体移植物进行ACLR后的等速强度和患者报告的结果,以确定移植物特异性恢复模式。方法:系统地检索PubMed、Cochrane Library、EMBASE和谷歌Scholar,以比较评估QT、HT或BTB自体移植物原发性ACLR后等动强度的研究。非英文、不可获得的全文、动物/尸体和身体保护研究被排除在外。minor和Detsky评估了偏倚风险。结果:纳入17项研究(1705例患者:QT = 765, HT = 725, BTB = 215),随访48个月。由于数据异质性,每项荟萃分析有4 - 6项研究符合条件。在13项QT vs HT研究中,QT移植物显示9例(56.3%)伸肌强度较弱,6例(37.5%)屈肌强度较大。在4项(25.0%)和7项(43.8%)研究中,分别没有报道伸肌或屈肌强度的差异。对于QT与BTB,两项研究(12.5%)显示了相似的伸肌强度,而两项研究报告了相互矛盾的结果。一项(6.3%)QT研究的屈肌强度较高,三项(18.8%)研究的屈肌强度相似。QT和HT之间的术后疼痛相当。结论:ACLR术后自体QT移植比HT移植屈曲更强,伸展更弱。针对移植物特异性缺陷的量身定制的康复可能会加速康复。需要进一步的研究来阐明QT移植和BTB自体移植之间的结果。证据等级:四级。
{"title":"Quadriceps Tendon Graft Leads to Stronger Flexion and Weaker Extension of the Knee Than Hamstring Graft Post-ACLR: Systematic Review and Meta-Analysis.","authors":"Brandon A Young, James C Dawahare, Edward Lee Major, Eva L Morrison, Cailan L Feingold, Eric H Lin, Joseph N Liu, Austin V Stone","doi":"10.1007/s43465-025-01545-9","DOIUrl":"10.1007/s43465-025-01545-9","url":null,"abstract":"<p><strong>Purpose: </strong>The optimal autograft for restoring knee strength and expediting return-to-sport following anterior cruciate ligament reconstruction (ACLR) remains debated. This systematic review and meta-analysis compared isokinetic strength and patient-reported outcomes after ACLR using quadriceps tendon (QT), hamstring tendon (HT), or bone-patellar tendon-bone (BTB) autografts to determine graft-specific recovery patterns.</p><p><strong>Methods: </strong>PubMed, Cochrane Library, EMBASE, and Google Scholar were systematically searched for comparative studies evaluating isokinetic strength following primary ACLR using QT, HT, or BTB autografts. Non-English, unavailable full-text, animal/cadaveric, and physeal-sparing studies were excluded. MINORS and Detsky evaluated bias risk. Key findings were quantified, and subgroup meta-analyses were performed on limb symmetry index (LSI) values (significance: <i>p</i> < 0.05).</p><p><strong>Results: </strong>Seventeen studies (1,705 patients: QT = 765, HT = 725, BTB = 215) with follow-ups through 48 months were included. Due to data heterogeneity, four to six studies qualified for each meta-analysis. Among 13 QT vs. HT studies, QT grafts demonstrated weaker extensor strength in nine (56.3%) and greater flexor strength in six (37.5%). No differences were reported in extensor or flexor strength in four (25.0%) and seven (43.8%) studies, respectively. For QT vs. BTB, two studies (12.5%) showed similar extensor strength, whereas two reported conflicting results. QT had greater flexor strength in one (6.3%) and similar strength in three (18.8%) studies. Postoperative pain was comparable between QT and HT.</p><p><strong>Conclusions: </strong>QT autografts resulted in stronger flexion and weaker extension than HT autografts after ACLR. Tailored rehabilitation targeting graft-specific deficits may accelerate recovery. Further research is required to clarify outcomes between QT and BTB autografts.<i>Level of evidence</i>: IV.</p>","PeriodicalId":13338,"journal":{"name":"Indian Journal of Orthopaedics","volume":"59 12","pages":"2026-2038"},"PeriodicalIF":1.1,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12696245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145756284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global High-Cited Pediatric Fracture Research: Bibliometric Assessment of Scopus Publications (1929-2024). 全球高被引儿童骨折研究:Scopus出版物的文献计量评估(1929-2024)。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-12 eCollection Date: 2026-01-01 DOI: 10.1007/s43465-025-01551-x
Raju Vaishya, Ashok N Johari, Brij Mohan Gupta, Mallikarjun M Kappi, Ghouse Modin Naseesab Mamdapur, Abhishek Vaish

Purpose: This study aimed to explore the bibliometric characteristics of pediatric fracture research from its inception until 2024, specifically focusing on high-cited publications (HCPs) defined as those with 100 or more citations. Key indicators evaluated include publication frequency, citation counts, and collaboration metrics.

Methodology: The Scopus database was utilized to identify global publications related to pediatric fractures. The top HCPs were retrieved for detailed analysis, employing bibliometric and network analyses with VOSviewer and Biblioshiny software to uncover key contributors, including organizations, authors, and journals, along with their collaborative interactions and significant keyword co-occurrences.

Results: 262 HCPs in pediatric fracture research were identified and indexed in Scopus from 1929 to 2024 (95 years), accumulating a cumulative citation count of 42,675 and an average of 162.9 citations per publication. This body of work involved 931 authors from 160 organizations across 31 countries, with external funding at 9.16% and international collaboration at 7.25%. The United States of America was the leading contributor with 145 publications (55.34%), followed by the United Kingdom (11.83%) and Canada (11.45%). The Children's Hospital of Philadelphia emerged as the most productive organization, while the Journal of Pediatric Orthopaedics published the highest number of HCPs (n = 59). The journal 'Bone' exhibited the highest citation impact per paper, averaging 271.33 citations.

Conclusion: This study elucidates research trends and influential contributions in pediatric fracture research, offering valuable insights into past, present, and future research priorities in this domain.

Graphical abstract:

Supplementary information: The online version contains supplementary material available at 10.1007/s43465-025-01551-x.

目的:本研究旨在探索从成立到2024年儿童骨折研究的文献计量学特征,特别关注高被引出版物(HCPs),即被引次数在100次或以上的出版物。评估的关键指标包括发表频率、引用次数和协作指标。方法:利用Scopus数据库识别与儿童骨折相关的全球出版物。通过使用VOSviewer和Biblioshiny软件进行文献计量学和网络分析,检索顶级HCPs进行详细分析,以发现关键贡献者,包括组织,作者和期刊,以及他们的协作互动和重要的关键词共现。结果:1929 - 2024年(95年)Scopus共检索到262篇儿童骨折研究HCPs,累计被引42675次,平均每篇被引162.9次。这项工作涉及来自31个国家160个组织的931位作者,外部资助占9.16%,国际合作占7.25%。美国是最大的贡献者,有145篇(55.34%),其次是英国(11.83%)和加拿大(11.45%)。费城儿童医院(Children's Hospital of Philadelphia)成为最具生产力的组织,而《儿科骨科杂志》(Journal of Pediatric orthopopaics)发表的hcp数量最多(n = 59)。期刊《Bone》每篇论文的引用影响最高,平均被引用271.33次。结论:本研究阐明了儿童骨折研究的研究趋势和有影响的贡献,为该领域过去、现在和未来的研究重点提供了有价值的见解。图片摘要:补充资料:在线版本包含补充资料,网址为10.1007/s43465-025-01551-x。
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引用次数: 0
Hoffa-Kastert Syndrome: A Rare Cause of Acute Knee Blockade. Hoffa-Kastert综合征:急性膝关节阻塞的罕见原因。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-12 eCollection Date: 2025-11-01 DOI: 10.1007/s43465-025-01534-y
Jan Peters, Hans-Christian Koehler, Peter Rexin, Martin Zwaan, Thomas Reichel, Christoph Schulze

Background: The Hoffa-Kastert syndrome was first described at the beginning of the twentieth century (Hoffa in Deutsche Medizinische Wochenschrift 30:337-338, 1904). The assumption of an independent disease of Hoffa's fat pad was extended by Kastert in the midtwentieth century with the finding that another pathology in the knee must be the cause for the inflammatory change ("Hoffaitis") (Kastert in Chirurg 24:390-394, 1953).

Case report: The fat pad can increase in size as a result of repeated trauma and lead to entrapment as described here.

Conclusion: Complete removal of the circumscribed tumour could eliminate the joint blockage.

背景:Hoffa- kastert综合征在20世纪初首次被描述(Hoffa in Deutsche Medizinische Wochenschrift 30:37 - 338,1904)。Kastert在20世纪中期提出了Hoffa脂肪垫是一种独立疾病的假设,发现膝关节的另一种病理必须是炎症变化的原因(“Hoffaitis”)(Kastert in Chirurg 24:39 -394, 1953)。病例报告:由于反复的创伤,脂肪垫的大小会增加,并导致此处所描述的夹住。结论:完全切除围界肿瘤可消除关节阻塞。
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引用次数: 0
Serum Albumin Role as a Prognostic Biomarker of Radiological Gonarthrosis Progression: A Retrospective Cross-sectional Study. 血清白蛋白作为放射关节病进展的预后生物标志物:一项回顾性横断面研究。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-11 eCollection Date: 2025-12-01 DOI: 10.1007/s43465-025-01561-9
Elzem Bolkan Günaydın, Saime Ay

Aims: To evaluate the prognostic role of serum albumin level in the radiological progression of gonarthrosis.

Methods: Two hundered and fifty patients with gonarthrosis (Group1: early stage gonarthrosis, Group 2: late-stage gonarthrosis), and 125 patients as a control group (Group 3) were included in this retrospective cross-sectional study. Age, gender, the Kellgren-Lawrence (KL) stage, serum albumin level, C-reactive protein (CRP)/albumin, platelet/lymphocyte, neutrophil/lymphocyte, lymphocyte/monocyte, lymphocyte/CRP, The Aggregate Index of Systemic Inflammation, Systemic Inflammatory Response Index, Systemic Immune Inflammation Index, Prognostic Nutritional Index (PNI), Modified Systemic Inflammation Score (mSIS) were recorded.

Results: Albumin and PNI were lower compared to the Group 3 in the Group 1 and Group 2, and compared to the Group 1 in the Group 2 (for all p ≤ 0.001). mSIS was higher in the Group 1 and Group 2 compared to the Group 3 (p < 0.001 for both), and in the Group 2 compared to the Group 1 (p = 0.01). CRP/albumin was higher in Group 2 compared to Group 1 (p = 0.004). KL stage was moderately negatively correlated with albumin (r = -0.45 p < 0,001) and PNI (r = -0.40 p < 0.001). Albumin and PNI values ​have diagnostic value in predicting early-stage (the cut-off value for albumin: 40.05 g/L, for PNI: 52.28) and late-stage (the cut-off value for albumin: 39.35 g/L, for PNI: 51.03) gonarthrosis in patients without gonarthrosis and late-stage gonarthrosis in patients with early-stage gonarthrosis (the cut-off value for albumin level: 38.55 g/L, for PNI: 49.73).

Conclusions: Serum albumin level has a prognostic role in the radiological progression of gonarthrosis.

目的:评价血清白蛋白水平在关节病放射学进展中的预后作用。方法:采用回顾性横断面研究方法,选取250例膝关节炎患者(第一组:早期膝关节炎,第二组:晚期膝关节炎)和125例作为对照组(第三组)。记录患者年龄、性别、Kellgren-Lawrence (KL)分期、血清白蛋白水平、c -反应蛋白(CRP)/白蛋白、血小板/淋巴细胞、中性粒细胞/淋巴细胞、淋巴细胞/单核细胞、淋巴细胞/CRP、全身炎症综合指数、全身炎症反应指数、全身免疫炎症指数、预后营养指数(PNI)、改良全身炎症评分(mSIS)。结果:1、2组患者白蛋白和PNI均低于3组,2组患者白蛋白和PNI均低于1组(p均≤0.001)。组1和组2的mSIS均高于组3 (p p = 0.01)。2组CRP/白蛋白高于1组(p = 0.004)。结论:血清白蛋白水平对关节病的放射学进展具有预测作用。
{"title":"Serum Albumin Role as a Prognostic Biomarker of Radiological Gonarthrosis Progression: A Retrospective Cross-sectional Study.","authors":"Elzem Bolkan Günaydın, Saime Ay","doi":"10.1007/s43465-025-01561-9","DOIUrl":"https://doi.org/10.1007/s43465-025-01561-9","url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the prognostic role of serum albumin level in the radiological progression of gonarthrosis.</p><p><strong>Methods: </strong>Two hundered and fifty patients with gonarthrosis (Group1: early stage gonarthrosis, Group 2: late-stage gonarthrosis), and 125 patients as a control group (Group 3) were included in this retrospective cross-sectional study. Age, gender, the Kellgren-Lawrence (KL) stage, serum albumin level, C-reactive protein (CRP)/albumin, platelet/lymphocyte, neutrophil/lymphocyte, lymphocyte/monocyte, lymphocyte/CRP, The Aggregate Index of Systemic Inflammation, Systemic Inflammatory Response Index, Systemic Immune Inflammation Index, Prognostic Nutritional Index (PNI), Modified Systemic Inflammation Score (mSIS) were recorded.</p><p><strong>Results: </strong>Albumin and PNI were lower compared to the Group 3 in the Group 1 and Group 2, and compared to the Group 1 in the Group 2 (for all <i>p</i> ≤ 0.001). mSIS was higher in the Group 1 and Group 2 compared to the Group 3 (<i>p</i> < 0.001 for both), and in the Group 2 compared to the Group 1 (<i>p</i> = 0.01). CRP/albumin was higher in Group 2 compared to Group 1 (<i>p</i> = 0.004). KL stage was moderately negatively correlated with albumin (<i>r</i> = -0.45 <i>p</i> < 0,001) and PNI (<i>r</i> = -0.40 <i>p</i> < 0.001). Albumin and PNI values ​have diagnostic value in predicting early-stage (the cut-off value for albumin: 40.05 g/L, for PNI: 52.28) and late-stage (the cut-off value for albumin: 39.35 g/L, for PNI: 51.03) gonarthrosis in patients without gonarthrosis and late-stage gonarthrosis in patients with early-stage gonarthrosis (the cut-off value for albumin level: 38.55 g/L, for PNI: 49.73).</p><p><strong>Conclusions: </strong>Serum albumin level has a prognostic role in the radiological progression of gonarthrosis.</p>","PeriodicalId":13338,"journal":{"name":"Indian Journal of Orthopaedics","volume":"59 12","pages":"2107-2118"},"PeriodicalIF":1.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12696227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145756289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of a Method to Quantify the Cortical Thickness of the Posterolateral Vertebral Arch on MRI. 一种在MRI上量化椎弓后外侧皮质厚度方法的可靠性。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-09-10 eCollection Date: 2026-02-01 DOI: 10.1007/s43465-025-01504-4
Richard Saw, Kevin Sims, Anna Saw, Jeremy Witchalls, David Connell, Alex Kountouris, Gordon Waddington, Greg Lovell, John Orchard

Background: Lumbar stress fractures are very common lesions in young athletes participating in sport and are generally now diagnosed on MRI scanning. An ability to assess cortical thickness would help understand risk for future injury. This paper aims to establish a method for quantifying cortical thickness in the posterolateral vertebral arch of the lumbar spine on MRI scans.

Methods: Methods for measuring the cortical thickness of the pars, pedicle, and lamina of the lumbar vertebra were developed from existing methods in other bones and expert opinion. MRI images of elite cricket pace bowlers were retrospectively reviewed in a development phase (n = 13 MRI, 30 measurement sites per MRI) and a reliability testing phase (inter-rater reliability n = 33 MRI, intra-rater reliability n-12 MRI).

Results: Intra-rater reliability was overall excellent (intra-class correlation coefficient (ICC) 0.740-0.992). Inter-rater reliability ranged from fair to excellent (ICC 0.515-0.954), with lower reliability for the total pedicle cortex. Lower reliability was attributable to challenges of identifying the pedicle cortex and the more oblique orientation of the L5 vertebrae as the lumbar spine becomes more lordotic.

Conclusion: This paper establishes a new manual method to quantify cortical thickness in the posterolateral vertebral arch of the lumbar spine on MRI scans. This work supports future advancements by providing a reference standard for potential automation using artificial intelligence and to understand how cortical thickness may be related to adaptation and injury in athletes at high risk of lumbar bone stress injury.

背景:腰椎应力性骨折是参加运动的年轻运动员中非常常见的病变,现在通常通过MRI扫描诊断。评估皮质厚度的能力将有助于了解未来受伤的风险。本文旨在建立一种在MRI扫描上量化腰椎后外侧椎弓皮质厚度的方法。方法:根据现有的其他骨骼测量方法和专家意见,开发了测量腰椎部、椎弓根和椎板皮质厚度的方法。在发展阶段(n = 13 MRI,每个MRI 30个测量点)和可靠性测试阶段(评分间可靠性n = 33 MRI,评分内可靠性n-12 MRI)回顾性回顾了优秀板球速度保龄球运动员的MRI图像。结果:组内信度总体优良(组内相关系数(ICC) 0.740 ~ 0.992)。评级间信度范围从一般到优秀(ICC 0.515-0.954),总蒂皮质的信度较低。较低的可靠性可归因于识别椎弓根皮质的挑战,以及随着腰椎变得更加前凸,L5椎体的方向更加倾斜。结论:本文建立了一种在MRI扫描上量化腰椎后外侧椎弓皮质厚度的新方法。这项工作通过为潜在的人工智能自动化提供参考标准,并了解皮质厚度如何与腰椎应力性损伤高风险运动员的适应和损伤相关,从而支持未来的进展。
{"title":"Reliability of a Method to Quantify the Cortical Thickness of the Posterolateral Vertebral Arch on MRI.","authors":"Richard Saw, Kevin Sims, Anna Saw, Jeremy Witchalls, David Connell, Alex Kountouris, Gordon Waddington, Greg Lovell, John Orchard","doi":"10.1007/s43465-025-01504-4","DOIUrl":"10.1007/s43465-025-01504-4","url":null,"abstract":"<p><strong>Background: </strong>Lumbar stress fractures are very common lesions in young athletes participating in sport and are generally now diagnosed on MRI scanning. An ability to assess cortical thickness would help understand risk for future injury. This paper aims to establish a method for quantifying cortical thickness in the posterolateral vertebral arch of the lumbar spine on MRI scans.</p><p><strong>Methods: </strong>Methods for measuring the cortical thickness of the pars, pedicle, and lamina of the lumbar vertebra were developed from existing methods in other bones and expert opinion. MRI images of elite cricket pace bowlers were retrospectively reviewed in a development phase (<i>n</i> = 13 MRI, 30 measurement sites per MRI) and a reliability testing phase (inter-rater reliability <i>n</i> = 33 MRI, intra-rater reliability <i>n</i>-12 MRI).</p><p><strong>Results: </strong>Intra-rater reliability was overall excellent (intra-class correlation coefficient (ICC) 0.740-0.992). Inter-rater reliability ranged from fair to excellent (ICC 0.515-0.954), with lower reliability for the total pedicle cortex. Lower reliability was attributable to challenges of identifying the pedicle cortex and the more oblique orientation of the L5 vertebrae as the lumbar spine becomes more lordotic.</p><p><strong>Conclusion: </strong>This paper establishes a new manual method to quantify cortical thickness in the posterolateral vertebral arch of the lumbar spine on MRI scans. This work supports future advancements by providing a reference standard for potential automation using artificial intelligence and to understand how cortical thickness may be related to adaptation and injury in athletes at high risk of lumbar bone stress injury.</p>","PeriodicalId":13338,"journal":{"name":"Indian Journal of Orthopaedics","volume":"60 2","pages":"465-472"},"PeriodicalIF":1.1,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12883601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146156956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Indian Journal of Orthopaedics
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