Objective: In our study, we aimed to compare the dose distrubutions of Accuray brand TomoTherapy device Volo treatment planning system lung stereoactic body radiation therapy (SBRT) and intensity-adjusted radiation therapy in cancer dose distributions obtained using (IMRT) techniques and environmental doses. Matetial and Method: Computed Tomography (CT) images of 7 patients were transferred to the MIM contouring station for dose measurement. CT target volume via image; PTV right or left lung, critical organs: heart, costa, esophagus, medulla, bilateral lung transferred to planning system. Lung tumors created virtually.In study 1 cm tumor of the size it is formed to be cm,3 cm and 5 cm. Spouse as lungtumor sizes change.in time, the cross-section (jaw) area of the TomoTherapy device will also be 1 cm, 2.5 cm and 5 cm it has been modified and tested for SBRT and IMRT techniques at each tumor size. Results: PTV dose treatment plans have been established to be 60 Gy and 3 fractions. The study 1 cm tumor of the size SBRT and IMRT techniques compared to the treatment of lung cancer as a result for 1 cm jaw, 2.5 cm jaw and 5 cm jaw in cm tumor size and 5 cm tumor PTV max, D95 values for 1 cm jaw used in size and bilateral, which is the critical organs. A significant difference in lung max values was found in favor of SBRT (p<0.05). 3 cm tumor size used in 1 cm, 2.5 cm and 5 cm jaw areas and 5 cm treatment compared to 2.5 and 5 cm jaw areas used in cm tumor bouts statistics on ptv max and bilateral lung max values at the end of the analysis, an agreed difference was found in favor of the SBRT (p<0.05) during treatment periods. At the end of statistical analysis in 1 cm jaw area used in 1 cm tumor size a significant difference in favor of IMRT has been identified.(p<0.05) and no significant differences were found for other critical organs (p > 0.05). Conclusion: As a result, 1 cm, 3 cm and 5 cm tumor sizes used in 1 cm, 2.5 cm and 5 cm section (jaw) areas according to both techniques preserved critical organs. But the SBRT technique showed better results in terms of target volume (PTV) and both lungs.
{"title":"Investigation of SBRT and IMRT Techniques in Lung Radiotherapy: A Dosimetric Study","authors":"E. Ates","doi":"10.38175/PHNX.961871","DOIUrl":"https://doi.org/10.38175/PHNX.961871","url":null,"abstract":"Objective: In our study, we aimed to compare the dose distrubutions of Accuray brand TomoTherapy device Volo treatment planning system lung stereoactic body radiation therapy (SBRT) and intensity-adjusted radiation therapy in cancer dose distributions obtained using (IMRT) techniques and environmental doses. Matetial and Method: Computed Tomography (CT) images of 7 patients were transferred to the MIM contouring station for dose measurement. CT target volume via image; PTV right or left lung, critical organs: heart, costa, esophagus, medulla, bilateral lung transferred to planning system. Lung tumors created virtually.In study 1 cm tumor of the size it is formed to be cm,3 cm and 5 cm. Spouse as lungtumor sizes change.in time, the cross-section (jaw) area of the TomoTherapy device will also be 1 cm, 2.5 cm and 5 cm it has been modified and tested for SBRT and IMRT techniques at each tumor size. Results: PTV dose treatment plans have been established to be 60 Gy and 3 fractions. The study 1 cm tumor of the size SBRT and IMRT techniques compared to the treatment of lung cancer as a result for 1 cm jaw, 2.5 cm jaw and 5 cm jaw in cm tumor size and 5 cm tumor PTV max, D95 values for 1 cm jaw used in size and bilateral, which is the critical organs. A significant difference in lung max values was found in favor of SBRT (p<0.05). 3 cm tumor size used in 1 cm, 2.5 cm and 5 cm jaw areas and 5 cm treatment compared to 2.5 and 5 cm jaw areas used in cm tumor bouts statistics on ptv max and bilateral lung max values at the end of the analysis, an agreed difference was found in favor of the SBRT (p<0.05) during treatment periods. At the end of statistical analysis in 1 cm jaw area used in 1 cm tumor size a significant difference in favor of IMRT has been identified.(p<0.05) and no significant differences were found for other critical organs (p > 0.05). Conclusion: As a result, 1 cm, 3 cm and 5 cm tumor sizes used in 1 cm, 2.5 cm and 5 cm section (jaw) areas according to both techniques preserved critical organs. But the SBRT technique showed better results in terms of target volume (PTV) and both lungs.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125913871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Necip Gokhan Guner, Ensar Durmuş, Fatih Güneysu, Y. Yürümez, Nuray Aslan
In this study, a COVID-19 reverse transcription polymerase chain reaction (RT-PCR) positive case who died in the hospital with pneumonia after receiving two doses of inactive CoronaVac (Sinovac Life Sciences) vaccine is presented. A 67-year-old female patient, who was vaccinated with two doses of the Coronovac vaccine, was admitted to the emergency room (ER) with dyspnea and cough. There was a bilateral ground glass image on thorax tomography. The patient’s RT-PCR test was positive, and he was admitted to the hospital’s V-19 ward. The patient, who stayed in the service for three days
{"title":"Death Despite Covid-19 Vaccine: Case Report","authors":"Necip Gokhan Guner, Ensar Durmuş, Fatih Güneysu, Y. Yürümez, Nuray Aslan","doi":"10.38175/phnx.936059","DOIUrl":"https://doi.org/10.38175/phnx.936059","url":null,"abstract":"In this study, a COVID-19 reverse transcription polymerase chain reaction (RT-PCR) positive case who died in the hospital with pneumonia after receiving two doses of inactive CoronaVac (Sinovac Life Sciences) vaccine is presented. A 67-year-old female patient, who was vaccinated with two doses of the Coronovac vaccine, was admitted to the emergency room (ER) with dyspnea and cough. There was a bilateral ground glass image on thorax tomography. The patient’s RT-PCR test was positive, and he was admitted to the hospital’s V-19 ward. The patient, who stayed in the service for three days","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132935601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acil Tıbbi Tedavi Sistemlerin Organizasyonu ve Coğrafi Bilgi Sistemleri","authors":"Serdar Özdemir, Kadir Şahbaz","doi":"10.38175/phnx.957367","DOIUrl":"https://doi.org/10.38175/phnx.957367","url":null,"abstract":"","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121048388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Öyküm Genç, Erdi Akar, E. Arpacı, Hüseyin Engi̇n, S. Çelik
Sitokinler, bagisiklik sisteminin homeostazini duzenlemek icin hucreler arasi sinyallesmenin aracilari olarak gorev yapan, salgilanan veya zara bagli proteinlerdir. Mikroplara ve tumor antijenlerine yanit olarak dogustan gelen bagisikliga sahip hucreler tarafindan uretilirler. IL2-330 gen polimorfizminin bircok kanser turu ile iliskili oldugunu gosteren birkac calisma olmasina ragmen, bildigimiz kadariyla akciger kanseri ile IL2-330 gen polimorfizmi arasindaki iliskiyi arastiran az sayida calisma vardir. Bu calismada IL2-330 gen polimorfizminin akciger kanseri patogenezindeki rolu arastirilmistir. Calismaya akciger kanseri tanisi almis 96 hasta ile yas ve cinsiyet bakimindan uyumlu 96 saglikli, gonullu birey katildi. Genomik DNA izolasyon kiti kullanilarak izole edildi ve IL2 -330 gen polimorfizmi polimeraz zincir reaksiyonu ile iki cift primer yontemiyle karsilastirilarak belirlendi. Akciger kanserinde IL2-330 gen polimorfizmine gore hasta grubu ve saglikli grup incelendiginde genotip ve allel frekanslarinin her iki grupta benzer oldugu goruldu (p>0,05). Sonuc olarak gruplar arasinda istatistiksel olarak anlamli bir fark yoktu. Akciger kanserinin etnik cesitliligi goz onune alindiginda, calismanin diger populasyonlarda da dogrulanmasi gerekmektedir.
{"title":"Association of IL2-330 Gene Polymorphism with Lung Cancer","authors":"Öyküm Genç, Erdi Akar, E. Arpacı, Hüseyin Engi̇n, S. Çelik","doi":"10.38175/phnx.888875","DOIUrl":"https://doi.org/10.38175/phnx.888875","url":null,"abstract":"Sitokinler, bagisiklik sisteminin homeostazini duzenlemek icin hucreler arasi sinyallesmenin aracilari olarak gorev yapan, salgilanan veya zara bagli proteinlerdir. Mikroplara ve tumor antijenlerine yanit olarak dogustan gelen bagisikliga sahip hucreler tarafindan uretilirler. IL2-330 gen polimorfizminin bircok kanser turu ile iliskili oldugunu gosteren birkac calisma olmasina ragmen, bildigimiz kadariyla akciger kanseri ile IL2-330 gen polimorfizmi arasindaki iliskiyi arastiran az sayida calisma vardir. Bu calismada IL2-330 gen polimorfizminin akciger kanseri patogenezindeki rolu arastirilmistir. Calismaya akciger kanseri tanisi almis 96 hasta ile yas ve cinsiyet bakimindan uyumlu 96 saglikli, gonullu birey katildi. Genomik DNA izolasyon kiti kullanilarak izole edildi ve IL2 -330 gen polimorfizmi polimeraz zincir reaksiyonu ile iki cift primer yontemiyle karsilastirilarak belirlendi. Akciger kanserinde IL2-330 gen polimorfizmine gore hasta grubu ve saglikli grup incelendiginde genotip ve allel frekanslarinin her iki grupta benzer oldugu goruldu (p>0,05). Sonuc olarak gruplar arasinda istatistiksel olarak anlamli bir fark yoktu. Akciger kanserinin etnik cesitliligi goz onune alindiginda, calismanin diger populasyonlarda da dogrulanmasi gerekmektedir.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114837841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"WPW Induced Ventricular Tachycardia in a Patient Using Quetiapine","authors":"Adem Kaya","doi":"10.38175/phnx.882420","DOIUrl":"https://doi.org/10.38175/phnx.882420","url":null,"abstract":"","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133287648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 Pandemisi Ne Zaman Bitecek? Hedefe Ne Kadar Yakınız?","authors":"Serhat Sirekbasan, Serap Suzuk","doi":"10.38175/phnx.894632","DOIUrl":"https://doi.org/10.38175/phnx.894632","url":null,"abstract":"","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123133853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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