Purpose : All over the world, a specific antiviral and immunomodulatory treatment method that can affect COVID-19 infection has not been found, and research is ongoing. Our goal is to share our clinical experience in patients receiving in patient treatment in our clinic. Materials and Methods: Patients whose symptoms were compatible with COVID-19 and whose microbiological findings and/ortomography findings were compatible between March 11 and May 31, 2020 were included in the study. Results: Among 180 patients included in the study; It was found that favipiravir treatment was added to 45 (25.0%) patients after HCQ treatment. A significant difference was found between treatment groups concerning; age, occupation, oxygen saturation, presence of Diabetes Mellitus, Hypertansion and lung disease, and CT findings (p
{"title":"Covid-19 Tanısı alan hastalarda tedavi ve klinik deneyimler","authors":"İ. Yildiz, İlkay Bahçeci̇","doi":"10.38175/phnx.1240296","DOIUrl":"https://doi.org/10.38175/phnx.1240296","url":null,"abstract":"Purpose : All over the world, a specific antiviral and immunomodulatory treatment method that can affect COVID-19 infection has not been found, and research is ongoing. Our goal is to share our clinical experience in patients receiving in patient treatment in our clinic. \u0000Materials and Methods: Patients whose symptoms were compatible with COVID-19 and whose microbiological findings and/ortomography findings were compatible between March 11 and May 31, 2020 were included in the study. \u0000Results: Among 180 patients included in the study; It was found that favipiravir treatment was added to 45 (25.0%) patients after HCQ treatment. A significant difference was found between treatment groups concerning; age, occupation, oxygen saturation, presence of Diabetes Mellitus, Hypertansion and lung disease, and CT findings (p","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"178 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122788803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Thoracic traumas are the third most common trauma among all trauma cases after head-neck and extremity traumas. The most common causes are motor vehicle accidents, falls from height, gunshot wounds, and stab wounds. In our study, it was aimed to investigate the mechanism of trauma and its effect on the frequency of accompanying vertebral fracture in patients who applied to the emergency department of a university hospital due to thoracic trauma. Material – Method: Our study was planned retrospectively. The information of the patients who applied to the emergency department of our hospital between 01.01.2017 and 01.01.2021 due to thoracic trauma was examined. Demographic characteristics of the patients, mechanism of trauma, trauma-related thoracic injuries and accompanying vertebral fractures were evaluated. Results: The data of 515 patients exposed to thoracic trauma were analyzed. The median age of the patients included in the study was 52 and 72.4% (n: 373) were male. 96.3% (n: 496) of the patients presented because of blunt trauma. The most common trauma mechanisms were in-vehicle traffic accident (46.6% n:240) and falling from height (30.9% n:159). Pneumothorax was found in 34.7% (n: 179) of the patients, hemothorax in 40.2% (n: 207), and costal fracture in 81.9% (n: 422). The frequency of concomitant vertebral fracture was 33.98% (n: 175). Vertebral fractures were most commonly detected in the lumbar region (53.1%) and were most common in patients admitted after a non-vehicle traffic accident. A significant difference was found between the mechanism of trauma and accompanying vertebral fracture; vertebral fracture was seen in 53.8% (n:28) of the patients who applied after a non-vehicle traffic accident. (p=0.004) Conclusion: It should be kept in mind that the trauma mechanism may increase the frequency of accompanying vertebral fracture in patients admitted to the emergency department after blunt trauma and evaluated for thoracic trauma.
{"title":"The effect of trauma mechanism on the frequency of accompanying vertebral fracture in cases with thoracic trauma","authors":"Beliz ÖZTOK TEKTEN, O. Yakşi","doi":"10.38175/phnx.1242837","DOIUrl":"https://doi.org/10.38175/phnx.1242837","url":null,"abstract":"Introduction: Thoracic traumas are the third most common trauma among all trauma cases after head-neck and extremity traumas. The most common causes are motor vehicle accidents, falls from height, gunshot wounds, and stab wounds. In our study, it was aimed to investigate the mechanism of trauma and its effect on the frequency of accompanying vertebral fracture in patients who applied to the emergency department of a university hospital due to thoracic trauma. \u0000Material – Method: Our study was planned retrospectively. The information of the patients who applied to the emergency department of our hospital between 01.01.2017 and 01.01.2021 due to thoracic trauma was examined. Demographic characteristics of the patients, mechanism of trauma, trauma-related thoracic injuries and accompanying vertebral fractures were evaluated. \u0000Results: The data of 515 patients exposed to thoracic trauma were analyzed. The median age of the patients included in the study was 52 and 72.4% (n: 373) were male. 96.3% (n: 496) of the patients presented because of blunt trauma. The most common trauma mechanisms were in-vehicle traffic accident (46.6% n:240) and falling from height (30.9% n:159). \u0000Pneumothorax was found in 34.7% (n: 179) of the patients, hemothorax in 40.2% (n: 207), and costal fracture in 81.9% (n: 422). The frequency of concomitant vertebral fracture was 33.98% (n: 175). Vertebral fractures were most commonly detected in the lumbar region (53.1%) and were most common in patients admitted after a non-vehicle traffic accident. A significant difference was found between the mechanism of trauma and accompanying vertebral fracture; vertebral fracture was seen in 53.8% (n:28) of the patients who applied after a non-vehicle traffic accident. (p=0.004) \u0000Conclusion: It should be kept in mind that the trauma mechanism may increase the frequency of accompanying vertebral fracture in patients admitted to the emergency department after blunt trauma and evaluated for thoracic trauma.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117194619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Umran Şumeyse Elbahr, Y. Özdemir, Rıdvan Karaali, İlker Balkan, Neşe Saltoğlu, Fehmi Tabak, Birgül Mete
Objective: This study was conducted to describe the demographic, clinical, and microbiological characteristics of vertebral osteomyelitis in the last decade, mainly by comparing literature and the previous case series performed in our center. Material and Methods: This is a retrospective, observational, descriptive study performed between 2009-2019 at Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine. All patients were divided into three main groups: pyogenic (PVO), tuberculous (TVO) and brucellar (BVO). Results: A total of 100 cases were included in this study. Of these 100 patients, 59 had pyogenic, 15 had brucellar and 26 had tuberculous spondylodiscitis. The disease developed postoperatively in 22 (37.4%) of the 59 PVO cases. The common isolated microorganism was Staphylococcus aureus (n = 11), followed by coagulase negative staphylococci (n = 6). BVO rate was lower than previous case series (15 vs. 24). The median time to improvement in the laboratory findings after the administration of the appropriate treatment was 14 days. PET-CT was diagnostic in 81.8% of PVO patients, similar to MRI. However, PET-CT diagnosis rate was significantly low in TVO patients (3 out of 9, p = 0.040). Conclusion: S. aureus remained the most common etiologic agent. Coagulase negative staphylococci infection rate, mainly related to spinal surgery, and postoperative spondylodiscitis rate is higher than before. Brucellar VO rate is lower, which is mostly related to effective animal vaccination and pasteurization. Although, MRI is the gold standard, PET-CT is a promising technique in diagnosis for PVO.
{"title":"VERTEBRAL OSTEOMİYELİT: SON 10 YILDA NELER DEĞİŞTİ?","authors":"Umran Şumeyse Elbahr, Y. Özdemir, Rıdvan Karaali, İlker Balkan, Neşe Saltoğlu, Fehmi Tabak, Birgül Mete","doi":"10.38175/phnx.1239682","DOIUrl":"https://doi.org/10.38175/phnx.1239682","url":null,"abstract":"Objective: This study was conducted to describe the demographic, clinical, and microbiological characteristics of vertebral osteomyelitis in the last decade, mainly by comparing literature and the previous case series performed in our center. \u0000Material and Methods: This is a retrospective, observational, descriptive study performed between 2009-2019 at Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine. All patients were divided into three main groups: pyogenic (PVO), tuberculous (TVO) and brucellar (BVO). \u0000Results: A total of 100 cases were included in this study. Of these 100 patients, 59 had pyogenic, 15 had brucellar and 26 had tuberculous spondylodiscitis. The disease developed postoperatively in 22 (37.4%) of the 59 PVO cases. The common isolated microorganism was Staphylococcus aureus (n = 11), followed by coagulase negative staphylococci (n = 6). BVO rate was lower than previous case series (15 vs. 24). The median time to improvement in the laboratory findings after the administration of the appropriate treatment was 14 days. PET-CT was diagnostic in 81.8% of PVO patients, similar to MRI. However, PET-CT diagnosis rate was significantly low in TVO patients (3 out of 9, p = 0.040). \u0000Conclusion: S. aureus remained the most common etiologic agent. Coagulase negative staphylococci infection rate, mainly related to spinal surgery, and postoperative spondylodiscitis rate is higher than before. Brucellar VO rate is lower, which is mostly related to effective animal vaccination and pasteurization. Although, MRI is the gold standard, PET-CT is a promising technique in diagnosis for PVO.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133633974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdullah Bi̇lge, A. Duman, K. Türkdoğan, Ayhan Aköz
Amaç: Pulmoner emboli teşhis edilemediğinde yüksek ölüm oranı ile ilişkilidir. . Amacımız fibrinojen/albümin oranı ile pulmoner emboli arasındaki ilişkiyi araştırmaktı. Yöntem: PE olduğundan şüphelenilen ve rutin kan testi yapılan hastalar bu prospektif çalışmaya dahil edilmiştir. Fibrinojenleri ve albümin değerleri değerlendirildi. Bulgular: Çalışmaya toplam 130 hasta dahil edildi. PE, hastaların 71'inde (%54) tespit edildi. Bunlardan 7'si (%9,9) alt segment, 50'si (%70,4) segmental ve 14'ü (%19,7) masif pulmoner idi. Kontrol grubundaki deneklerin FAR(Fibrinojen albumin oranı) 'si 99.1 (75.2–167.9) idi, PE grubundaki FAR 151 (125.1–220.5), kontrol grubundan anlamlı derecede yüksekti değer (P < 0,001). PE grubunda ROC analizi yapıldığında FAR önemli bir öngörücü faktör oldu (AUC: 0.724; %95 GA = 0.635-0.814; P < 0.001). FAR , duyarlılık %77.5 ve özgüllük %61.0 idi. Sonuç: PE'li hastalarda fibrinojen düzeyleri ve FAR anlamlı olarak daha yüksekti.
目的：肺栓塞如果得不到诊断，死亡率很高。.我们的目的是研究纤维蛋白原/白蛋白比率与肺栓塞之间的关系。方法：这项前瞻性研究纳入了接受常规血液检查的疑似肺栓塞患者。对纤维蛋白原和白蛋白值进行评估。结果研究共纳入 130 名患者。71名患者（54%）被检测出患有 PE。其中，7 例（9.9%）为亚节段性，50 例（70.4%）为节段性，14 例（19.7%）为大块肺性。对照组受试者的 FAR（纤维蛋白原白蛋白比值）为 99.1（75.2-167.9），而 PE 组的 FAR 为 151（125.1-220.5），明显高于对照组（P < 0.001）。对 PE 组进行 ROC 分析时，FAR 是一个重要的预测因素（AUC：0.724；95% CI = 0.635-0.814；P < 0.001）。FAR 的灵敏度为 77.5%，特异性为 61.0%。结论PE 患者的纤维蛋白原水平和 FAR 均明显升高。
{"title":"Fibrinogen/Albumin Ratio in Patients with Pulmonary Embolism","authors":"Abdullah Bi̇lge, A. Duman, K. Türkdoğan, Ayhan Aköz","doi":"10.38175/phnx.1202390","DOIUrl":"https://doi.org/10.38175/phnx.1202390","url":null,"abstract":"Amaç: Pulmoner emboli teşhis edilemediğinde yüksek ölüm oranı ile ilişkilidir. \u0000. Amacımız fibrinojen/albümin oranı ile pulmoner emboli arasındaki ilişkiyi araştırmaktı. \u0000Yöntem: PE olduğundan şüphelenilen ve rutin kan testi yapılan hastalar \u0000bu prospektif çalışmaya dahil edilmiştir. Fibrinojenleri ve \u0000albümin değerleri değerlendirildi. \u0000Bulgular: Çalışmaya toplam 130 hasta dahil edildi. PE, hastaların 71'inde (%54) tespit edildi. \u0000Bunlardan 7'si (%9,9) alt segment, 50'si (%70,4) segmental ve 14'ü (%19,7) \u0000masif pulmoner idi. Kontrol grubundaki deneklerin FAR(Fibrinojen albumin oranı) 'si 99.1 (75.2–167.9) idi, \u0000PE grubundaki FAR 151 (125.1–220.5), kontrol grubundan anlamlı derecede yüksekti \u0000değer (P < 0,001). PE grubunda ROC analizi yapıldığında FAR \u0000önemli bir öngörücü faktör oldu (AUC: 0.724; %95 GA = 0.635-0.814; P < 0.001). FAR \u0000, duyarlılık %77.5 ve özgüllük %61.0 idi. \u0000Sonuç: PE'li hastalarda fibrinojen düzeyleri ve FAR anlamlı olarak daha yüksekti.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"603 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134379620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Bu çalışmada, başvuru sırasında ölçülen hematolojik parametrelere dayalı indeklerin karbonmonoksit zehirlenmesinin (COZ) şiddetini tahmin etmedeki rolü araştırıldı. Gereç ve yöntem: 2018 ve 2022 tarihleri arasında bir Eğitim ve Araştırma hastanesi acil servisinde COZ tanısı konulan toplam 183 hasta retrospektif olarak incelendi. Hastaların klinik şiddetini belirlemek için COHb ve laktat düzeyleri kullanıldı. Hastalar hafif-orta karbon monoksit zehirlenmesi (hafif-orta COZ) ve ciddi karbon monoksit zehirlenmesi (ciddi COZ) olarak iki gruba ayrıldı. Sistemik immün inflamasyon indeksi (SII), sistemik inflamatuar cevap indeksi (SIRI) ve sistemik inflamasyon toplam indeksi (AISI), nötrofil/lenfosit oranı (NLR), platelet/lenfosit oranı (PLR) ve monosit/lenfosit oranı (MLR) bu iki hasta grubu arasında karşılaştırıldı. Bulgular: SII, SIRI, AISI, NLR, PLR ve MLR açısından her iki grup arasında önemli farklılık vardı (p1519.14 iken, sensitivite %67.9 ve spesifite %63.7 idi (AUC: 0.708, p4.955 iken, sensitivite %60 ve spesifite %78.5 olarak bulundu (AUC:0.746, p
{"title":"Acil Serviste SII ve SIRI değerlerinin CO Zehirlenmesinin Şiddetini Tahmin Etmedeki Rolü","authors":"Tarık Acar, Birsen Erteki̇n","doi":"10.38175/phnx.1224860","DOIUrl":"https://doi.org/10.38175/phnx.1224860","url":null,"abstract":"Amaç: Bu çalışmada, başvuru sırasında ölçülen hematolojik parametrelere dayalı indeklerin karbonmonoksit zehirlenmesinin (COZ) şiddetini tahmin etmedeki rolü araştırıldı. \u0000Gereç ve yöntem: 2018 ve 2022 tarihleri arasında bir Eğitim ve Araştırma hastanesi acil servisinde COZ tanısı konulan toplam 183 hasta retrospektif olarak incelendi. Hastaların klinik şiddetini belirlemek için COHb ve laktat düzeyleri kullanıldı. Hastalar hafif-orta karbon monoksit zehirlenmesi (hafif-orta COZ) ve ciddi karbon monoksit zehirlenmesi (ciddi COZ) olarak iki gruba ayrıldı. Sistemik immün inflamasyon indeksi (SII), sistemik inflamatuar cevap indeksi (SIRI) ve sistemik inflamasyon toplam indeksi (AISI), nötrofil/lenfosit oranı (NLR), platelet/lenfosit oranı (PLR) ve monosit/lenfosit oranı (MLR) bu iki hasta grubu arasında karşılaştırıldı. \u0000Bulgular: SII, SIRI, AISI, NLR, PLR ve MLR açısından her iki grup arasında önemli farklılık vardı (p1519.14 iken, sensitivite %67.9 ve spesifite %63.7 idi (AUC: 0.708, p4.955 iken, sensitivite %60 ve spesifite %78.5 olarak bulundu (AUC:0.746, p","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132200588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ÖZET Amaç: Acil servise başvurarak karbon monoksit zehirlenmesi teşhisi konulan hastaların analizi ve hastaların başvuru tarihlerinde görülen hava koşullarını değerlendirmek ve literatüre güncel bilgiler sunmaktır. Gereç ve Yöntem: İkinci basamak bir hastanede retrospektif olarak 01.01.2021-31.12.2021 tarihleri arasında T-58 ICD kodu ile karbon monoksit zehirlenmesi teşhisi konulan hastaların taranması ile yapılmıştır. Meteoroloji kurumundan alınan 2021 yılına ait hava durumu verileri ile karşılaştırmalar yapılmıştır. Bulgular: Çalışmada 169 hastaya karbon monoksit zehirlenmesi teşhisi konulduğu görüldü. Yaş ortalaması 35,20±22,58 olarak görüldü. En çok başvurunun kış aylarında ve gün içerisinde sabah saatlerinde olduğu görüldü. Hastaların karboksihemoglobin (COHb) değerleri ortalama 24,29±8,81 olarak ölçüldü. Kan laktat düzeyi ortalama 2,82±1,98 mmol/L olarak ölçüldü. COHb düzeyi ile laktat düzeyi arasında anlamlı ilişki olduğu görüldü. Vakaların görüldüğü günlerdeki rüzgâr yönü ortalaması 209,84º±94,3º olmuştur. Ortalama rüzgâr hızı ise 2,53±1,33 m/sn ve ortalama günlük yağış miktarı 4,69±6,89 kg/m² olmuştur. Sonuç: Karbon monoksit zehirlenmesi en sık kış aylarında görülmektedir. Çalışma sonuçlarına göre lodos rüzgârları olduğu günlerde anlamlı derecede vaka sayısında artış olmuştur. Zehirlenmelerin önüne geçilmesi için hava koşullarının takibi yapılmalı ve gerekli uyarılar yapılarak tedbirler alınmalıdır.
{"title":"Kapadokya Bölgesinde Karbonmonoksit Zehirlenmelerinin Analizi ve Meteorolojik Verilerle Karşılaştırılması","authors":"Mustafa Alpaslan","doi":"10.38175/phnx.1232423","DOIUrl":"https://doi.org/10.38175/phnx.1232423","url":null,"abstract":"ÖZET \u0000 \u0000Amaç: Acil servise başvurarak karbon monoksit zehirlenmesi teşhisi konulan hastaların analizi ve hastaların başvuru tarihlerinde görülen hava koşullarını değerlendirmek ve literatüre güncel bilgiler sunmaktır. \u0000Gereç ve Yöntem: İkinci basamak bir hastanede retrospektif olarak 01.01.2021-31.12.2021 tarihleri arasında T-58 ICD kodu ile karbon monoksit zehirlenmesi teşhisi konulan hastaların taranması ile yapılmıştır. Meteoroloji kurumundan alınan 2021 yılına ait hava durumu verileri ile karşılaştırmalar yapılmıştır. \u0000Bulgular: Çalışmada 169 hastaya karbon monoksit zehirlenmesi teşhisi konulduğu görüldü. Yaş ortalaması 35,20±22,58 olarak görüldü. En çok başvurunun kış aylarında ve gün içerisinde sabah saatlerinde olduğu görüldü. Hastaların karboksihemoglobin (COHb) değerleri ortalama 24,29±8,81 olarak ölçüldü. Kan laktat düzeyi ortalama 2,82±1,98 mmol/L olarak ölçüldü. COHb düzeyi ile laktat düzeyi arasında anlamlı ilişki olduğu görüldü. Vakaların görüldüğü günlerdeki rüzgâr yönü ortalaması 209,84º±94,3º olmuştur. Ortalama rüzgâr hızı ise 2,53±1,33 m/sn ve ortalama günlük yağış miktarı 4,69±6,89 kg/m² olmuştur. \u0000Sonuç: Karbon monoksit zehirlenmesi en sık kış aylarında görülmektedir. Çalışma sonuçlarına göre lodos rüzgârları olduğu günlerde anlamlı derecede vaka sayısında artış olmuştur. Zehirlenmelerin önüne geçilmesi için hava koşullarının takibi yapılmalı ve gerekli uyarılar yapılarak tedbirler alınmalıdır.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115046366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: Aim: Low intake of Vitamin B12 (vit B 12) with malabsorptions are the most critical factors causing the deficiency. Vit B 12 deficiency has also been associated with Helicobacter pylori (HP) gastritis in previous studies. This study's main goal is to find a similar relation with recent studies or an opposite conclusion. For this purpose we choose the most suitable group; patients with the same two diseases HP gastritis and vit B 12 deficiency. Patients and methods: The whole study was conducted retrospectively. İn the study we included 19 patients (mean age: 15.6 ± 1.3 years ). The B12 levels of patients undergoing upper gastroscopy for any reason were studied. We tried to figure out whether B12 deficiency and HP positivity were statistically significant. The Electrochemiluminescence immunoassay method has been used for serum vit B12 level measurement. Results: There are 15 (62.5%) patients with neurological symptoms and 6 (25.0%) patients with fatigue and weakness. Only 3 (12.5 %) patients have no symptoms. There was no statistical significance between these groups (p=0.224). There are 18 (75%) patients with HP positivity. HP positive and negative patients have levels of B12 108.6 ± 31.1 pg/mL and 113.5 ± 41.2 pg/mL respectively (p=973). Conclusion: There were no statistical significance with vitamin B 12 levels in HP-positive patients and HP-negative patients. İt sure be beneficial to use a bigger aspect patients group to have better results between HP infection and vitamin B 12 deficiency relation.
{"title":"Adolesanlarda B12 eksikliği ve Helikobakter Pylori Sıklığı","authors":"","doi":"10.38175/phnx.1233741","DOIUrl":"https://doi.org/10.38175/phnx.1233741","url":null,"abstract":"Abstract: \u0000Aim: Low intake of Vitamin B12 (vit B 12) with malabsorptions are the most critical factors causing the deficiency. Vit B 12 deficiency has also been associated with Helicobacter pylori (HP) gastritis in previous studies. This study's main goal is to find a similar relation with recent studies or an opposite conclusion. For this purpose we choose the most suitable group; patients with the same two diseases HP gastritis and vit B 12 deficiency. \u0000Patients and methods: The whole study was conducted retrospectively. İn the study we included 19 patients (mean age: 15.6 ± 1.3 years ). The B12 levels of patients undergoing upper gastroscopy for any reason were studied. We tried to figure out whether B12 deficiency and HP positivity were statistically significant. The Electrochemiluminescence immunoassay method has been used for serum vit B12 level measurement. \u0000Results: There are 15 (62.5%) patients with neurological symptoms and 6 (25.0%) patients with fatigue and weakness. Only 3 (12.5 %) patients have no symptoms. There was no statistical significance between these groups (p=0.224). There are 18 (75%) patients with HP positivity. HP positive and negative patients have levels of B12 108.6 ± 31.1 pg/mL and 113.5 ± 41.2 pg/mL respectively (p=973). \u0000 \u0000Conclusion: There were no statistical significance with vitamin B 12 levels in HP-positive patients and HP-negative patients. İt sure be beneficial to use a bigger aspect patients group to have better results between HP infection and vitamin B 12 deficiency relation.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"9 24","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120966111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Şahin, Eren Usul, Yıldız Yildirimer, Emrah Ari, Ali Halici, E. Arslan
AMAÇ: Travma hastalarında fizyolojik durumunun erken belirlenmesi uygulanacak tedavi yöntemlerinin hızlıca hayata geçirilmesi için yol gösterecek objektif kanıtlar yeterince bulunmamaktadır. Çalışmamızda literatür bilgileri eşliğinde kliniğimize delici kesici alet yaralanması nedeni ile başvuran olguları retrospektif olarak inceleyerek demografik özelliklerini, travma skorlarını ve laboratuvar sonuçlarını karşılaştırmayı amaçladık. GEREÇ VE YÖNTEM: 1 Ocak 2015 ile 31 Aralık 2016 tarihleri arasında acil servise başvuran delici kesici alet yaralanmaları retrospektif olarak incelendi. Çalışmaya alınma kriterlerine uygun 305 hastanın kaydına ulaşıldı. Çalışmaya alınan olgularda TA, nabız, solunum sayısı, GKS, RTS, ISS, NISS skorlmaları, hemoglobin, laktat, baz açığı ve şok indeksi değerleri hesaplandı. Bu hesaplanan değerlerle kan transfüzyonu ve cerrahi girişim ilişkisi istatistiksel olarak ele alındı. İstatistiksel yöntem SPSS kullanıldı. P
{"title":"DELİCİ – KESİCİ ALET YARALANMALARININ DEMOGRAFİK ÖZELLİKLERİ","authors":"Ali Şahin, Eren Usul, Yıldız Yildirimer, Emrah Ari, Ali Halici, E. Arslan","doi":"10.38175/phnx.1225008","DOIUrl":"https://doi.org/10.38175/phnx.1225008","url":null,"abstract":"AMAÇ: Travma hastalarında fizyolojik durumunun erken belirlenmesi uygulanacak tedavi yöntemlerinin hızlıca hayata geçirilmesi için yol gösterecek objektif kanıtlar yeterince bulunmamaktadır. Çalışmamızda literatür bilgileri eşliğinde kliniğimize delici kesici alet yaralanması nedeni ile başvuran olguları retrospektif olarak inceleyerek demografik özelliklerini, travma skorlarını ve laboratuvar sonuçlarını karşılaştırmayı amaçladık. \u0000GEREÇ VE YÖNTEM: 1 Ocak 2015 ile 31 Aralık 2016 tarihleri arasında acil servise başvuran delici kesici alet yaralanmaları retrospektif olarak incelendi. Çalışmaya alınma kriterlerine uygun 305 hastanın kaydına ulaşıldı. Çalışmaya alınan olgularda TA, nabız, solunum sayısı, GKS, RTS, ISS, NISS skorlmaları, hemoglobin, laktat, baz açığı ve şok indeksi değerleri hesaplandı. Bu hesaplanan değerlerle kan transfüzyonu ve cerrahi girişim ilişkisi istatistiksel olarak ele alındı. İstatistiksel yöntem SPSS kullanıldı. P","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131741240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Çil, I. Demir, M. Kabak, I. Hocanlı, M. Taylan, Mustafa Fi̇danten
Objective: Various Laboratory and vital parameters, including leukopenia, lymphopenia, neutrophil/lymphocyte ratio elevation, lactate dehydrogenase elevation, D-dimer and ferritin elevation, and low albumin can be used in the diagnosis and assessment of the severity of COVID-19 infection . Methods: The chest computed tomography (CT) scores, lymphopenia, neutrophil/lymphocyte ratio, neutrophil, lymphocyte, lactate dehydrogenase, albumin, C-reactive protein, white blood cells, platelets, basophil, eosinophil, monocytes, procalcitonin, D-dimer, ferritin, ages, genders, hospitalization units, oxygen-free fingertip saturations in room air, additional diseases and symptoms of 693 patients diagnosed with COVID-19 were recorded. The parameters of the patients were compared according to the severity of the chest CT score. Results: As a result of this study neutrophil/lymphocyte ratio was found to be significantly higher in the severe group when compared to the moderate group and the mild group. As chest CT score increased, lactate dehydrogenase level was higher at a statistically significant level in the severe group than in the mild group. Albumin levels were found to be lower in the severe group at a statistically significant level than in the mild group. Monocyte levels were found to be lower in the severe group at a statistically significant level when compared to the moderate and mild groups. Ferritin level was higher in the severe group at a statistically significant level when compared to the moderate and mild groups. When the practical effectiveness of using hematological and biochemical parameters to differentiate patients with severe CT scores from non-severe patients based on the chest CT score of the patients was examined by using the ROC Analysis, it was found that the neutrophil/lymphocyte ratio value had the strongest predictive ability (AUC, 0.787, SD=0.057, P
目的:白细胞减少、淋巴细胞减少、中性粒细胞/淋巴细胞比值升高、乳酸脱氢酶升高、d -二聚体和铁蛋白升高、低白蛋白等各项实验室及生命指标可用于诊断和评估COVID-19感染的严重程度。方法:记录693例确诊新冠肺炎患者的胸部CT评分、淋巴细胞减少、中性粒细胞/淋巴细胞比值、中性粒细胞、淋巴细胞、乳酸脱氢酶、白蛋白、c反应蛋白、白细胞、血小板、嗜碱性粒细胞、嗜酸性粒细胞、单核细胞、降钙素原、d -二聚体、铁蛋白、年龄、性别、住院单位、室内空气中无氧手指饱和度、附加疾病及症状。根据患者胸部CT评分的严重程度比较各参数。结果:本研究发现，重度组中性粒细胞/淋巴细胞比值明显高于中度组和轻度组。随着胸部CT评分的升高，重度组乳酸脱氢酶水平高于轻度组，且差异有统计学意义。重症组的白蛋白水平低于轻度组，且有统计学意义。与中度和轻度组相比，重度组单核细胞水平较低，具有统计学意义。重度组铁蛋白水平高于中度组和轻度组，差异有统计学意义。当应用ROC分析检验根据患者胸部CT评分用血清学生化参数区分重症CT评分与非重症CT评分的实际有效性时，发现中性粒细胞/淋巴细胞比值值的预测能力最强(AUC, 0.787, SD=0.057, P
{"title":"CHEST CT SCORE IN COVID-19 PATIENTS: THE RELATIONSHIP BETWEEN NEUTROPHIL-LYMPHOCYTE RATIO, MONOCYTE, LACTATE DEHYDROGENASE, ALBUMIN AND FERRITIN","authors":"B. Çil, I. Demir, M. Kabak, I. Hocanlı, M. Taylan, Mustafa Fi̇danten","doi":"10.38175/phnx.1199180","DOIUrl":"https://doi.org/10.38175/phnx.1199180","url":null,"abstract":"Objective: Various Laboratory and vital parameters, including leukopenia, lymphopenia, neutrophil/lymphocyte ratio elevation, lactate dehydrogenase elevation, D-dimer and ferritin elevation, and low albumin can be used in the diagnosis and assessment of the severity of COVID-19 infection . \u0000Methods: The chest computed tomography (CT) scores, lymphopenia, neutrophil/lymphocyte ratio, neutrophil, lymphocyte, lactate dehydrogenase, albumin, C-reactive protein, white blood cells, platelets, basophil, eosinophil, monocytes, procalcitonin, D-dimer, ferritin, ages, genders, hospitalization units, oxygen-free fingertip saturations in room air, additional diseases and symptoms of 693 patients diagnosed with COVID-19 were recorded. The parameters of the patients were compared according to the severity of the chest CT score. \u0000Results: As a result of this study neutrophil/lymphocyte ratio was found to be significantly higher in the severe group when compared to the moderate group and the mild group. As chest CT score increased, lactate dehydrogenase level was higher at a statistically significant level in the severe group than in the mild group. Albumin levels were found to be lower in the severe group at a statistically significant level than in the mild group. Monocyte levels were found to be lower in the severe group at a statistically significant level when compared to the moderate and mild groups. Ferritin level was higher in the severe group at a statistically significant level when compared to the moderate and mild groups. When the practical effectiveness of using hematological and biochemical parameters to differentiate patients with severe CT scores from non-severe patients based on the chest CT score of the patients was examined by using the ROC Analysis, it was found that the neutrophil/lymphocyte ratio value had the strongest predictive ability (AUC, 0.787, SD=0.057, P","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114426199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Achromobacter cinsi gram negatif bakterilere bağlı gelişen infeksiyonlar insanlarda oldukça nadir olmakla birlikte, literatürde ülkemizden de çeşitli vaka bildirimleri mevcuttur. Gereç ve Yöntem: Bu çalışmada A. denitrificans infeksiyonlarını ve klinik önemini gözden geçirmeyi amaçladık. Bulgular: Achromobacter spp. altta yatan hastalıkları olan, çeşitli invaziv girişimler uygulanan, uzun süre hastanede yatan hastalarda gelişen çeşitli nozokomiyal infeksiyonların (sepsis, yara enfeksiyonu, gibi) etkenleri arasındadır. Achromobacter spp. gerek toplum ve gerekse de sağlık bakımı ilişkili nadir bir infeksiyon etkenidir. Sonuç: Uygun tedavi seçeneklerini belirlemek için antibiyotik duyarlılık paterninin mutlaka çalışılması gerektiği unutulmamalıdır.
{"title":"Achromobacter xylosoxidans / denitrificans infeksiyonları: Literatürün gözden geçirilmesi","authors":"Emine Kübra DİNDAR DEMİRAY, Sevda Alkan","doi":"10.38175/phnx.1226628","DOIUrl":"https://doi.org/10.38175/phnx.1226628","url":null,"abstract":"Amaç: Achromobacter cinsi gram negatif bakterilere bağlı gelişen infeksiyonlar insanlarda oldukça nadir olmakla birlikte, literatürde ülkemizden de çeşitli vaka bildirimleri mevcuttur. Gereç ve Yöntem: Bu çalışmada A. denitrificans infeksiyonlarını ve klinik önemini gözden geçirmeyi amaçladık. \u0000Bulgular: Achromobacter spp. altta yatan hastalıkları olan, çeşitli invaziv girişimler uygulanan, uzun süre hastanede yatan hastalarda gelişen çeşitli nozokomiyal infeksiyonların (sepsis, yara enfeksiyonu, gibi) etkenleri arasındadır. Achromobacter spp. gerek toplum ve gerekse de sağlık bakımı ilişkili nadir bir infeksiyon etkenidir. \u0000Sonuç: Uygun tedavi seçeneklerini belirlemek için antibiyotik duyarlılık paterninin mutlaka çalışılması gerektiği unutulmamalıdır.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"296 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114953818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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