Indonesian Journal of Obstetrics and Gynecology最新文献

{"title":"Management of Spontaneous Cornual Heterotopic Pregnancy in Low-Resources Setting","authors":"Tata Laksana, Kehamilan Heterotopik, Kornual Spontan, Keadaan Sumber, Daya Terbatas, Jacklyn Y. G. Lubis, Yosep Sutandar, Lidya F. Nembo","doi":"10.32771/inajog.v11i3.1883","DOIUrl":"https://doi.org/10.32771/inajog.v11i3.1883","url":null,"abstract":"Objective: To report management of spontaneous cornualheterotopic pregnancy in low-resources setting in EndeDistrict, Flores, East Nusa Tenggara.Methods: Case report.Case: A 34 year old primigravida with history of 8-9 weeksamenorrhea came to Obstetrics ER with chief complaintof vaginal bleeding and lower abdominal pain. Ultrasoundshows intrauterine pregnancy (IUP), an ectopic pregnancy(EP) in right uterine cornu, and free fl uid in hepatorenalspace, splenorenal space, and pouch of douglas suggestingthe occurrence of hemoperitoneum and heterotopicpregnancy. We performed cornual resection by laparotomyand administered progesterone orally before and after thesurgery. Successful outcome was achieved.Discussion: Heterotopic pregnancy (HP) rarely occurs,especially in natural conception. Thus, early diagnosis andtreatment of HP are quite a challenge for physicians especiallyin rural area. Due to the condition of our patient and limitedresources, laparotomy was conducted to remove the EP,rather than laparoscopy despite its advantage to lower riskof IUP abortion. Progesterone was then administered orallyto prevent threatened abortion of the IUP.Conclusion: Despite its challenge in diagnosing andtreating HP, it is a life-threatening condition that requiresaccurate and prompt treatment. The treatment goal is toremove the EP and preserve the IUP. Treatment of choiceshould be decided by takeing the patient’s condition andavailability of resources into account. Surgical along withadministration of progesterone before and after the surgerywould likely improve the outcome of the patient and theintrauterine pregnancy.Keywords: cornual resection, heterotopic pregnancy,laparotomy, low-resources setting, progesterone.AbstrakTujuan: Untuk membahas tentang penatalaksanaankehamilan heterotopik kornu spontan di daerah dengansumber daya rendah khususnya di Kabupaten Ende, Flores,Nusa Tenggara Timur.Metode: Laporan KasusKasus: Seorang perempuan primigravida usia 34 tahundengan riwayat amenore minggu ke-8 dan 9 datang keIGD Obgyn dengan perdarahan pervaginam dan nyeriperut bagian bawah. Temuan USG menunjukkan kehamilanintrauterin (KIU), kehamilan ektopik (KE) di tanduk rahimkanan, dan cairan bebas di ruang hepato-renal, splenorenal,dan cavum douglas. Hal ini menunjukkan terjadinyahemoperitoneum dan kehamilan heterotopik. Reseksikornu dengan laparotomi dilakukan dan pasien diberikanprogesteron secara oral sebelum dan setelah operasi.Luaran baik berhasil dicapai.Diskusi: Kehamilan heterotopik jarang terjadi, terutamapada konsepsi alami. Sehingga diagnosis dan tata laksanaKH sejak dini menjadi tantangan bagi para dokter, terutamadi daerah terpencil Karena kondisi pasien dan sumber daya,laparotomi dilakukan untuk mengangkat KE, daripadalaparoskopi meskipun keuntungannya dalam menurunkanrisiko keguguran KIU. Progesteron kemudian diberikansecara oral untuk mencegah terjadinya keguguran terancamdari KIU.Kesimpulan: Terlepas dari tantangan untuk diagnosisdan tatalaksananya, KH ad","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44289545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroendocrine Cervical Carcinoma","authors":"Neuroendocrine Cervical Carcinoma, Adrian Djatikusumo, Yulian Prastisia, I. Effendi, Wina Kanya Wasystha, Karsinoma Serviks, Neuroendokrin","doi":"10.32771/inajog.v11i3.1898","DOIUrl":"https://doi.org/10.32771/inajog.v11i3.1898","url":null,"abstract":"Objective: To present a series of neuroendocrine cervical carcinoma, a rare malignancy of the cervix with different stages, treatment approach and outcome. It is included in this article review about diagnostic approach, treatment and prognosis in dealing with neuroendocrine cervical carcinoma.  \u0000Methods: Case report  \u0000Cases: We reported three cases of neuroendocrine cervical carcinoma. First is a 40-year old woman para 2, with stage IIIB neuroendocrine cervical carcinoma and chose palliative care only. Second, a 54-year old woman, para 5 with stage IIB  neuroendocrine cervical carcinoma which underwent radiotherapy, with a 4 months disease free period. And lastly, a 36-year old woman, para 2 with stage IB1 neuroendocrine cervical carcinoma, underwent a radical abdominal hysterectomy procedure with pelvic lymphadenectomy and external pelvic radiotherapy. The disease is well controlled and had no recurrence in 15 years. \u0000Conclusion: It is important to differentiate neuroendocrine cervical carcinoma with other malignancies that could be found in the cervix. Immunohistochemistry (IHC) tests could be used to achieve that purpose. It is also important to arrange a treatment plan to treat these malignancies and multimodality treatment is preferable for better outcomes. \u0000Keywords: Neuroendocrine cervical carcinoma, cervical carcinoma, multimodality treatment.AbstrakTujuan: Melaporkan serangkaian kasus neuroendocrinecervical carcinoma, salah satu jenis keganasan langka padaarea serviks dengan stadium, tata laksana, dan hasil yangberbeda. Dalam artikel ini juga terdapat ulasan mengenaiprosedur diagnosis, manajemen, dan prognosis darineuroendocrine cervical carcinoma.Metode: Laporan kasusKasus: Artikel ini melaporkan tiga kasus. Pertama perempuan40 tahun riwayat partus dua kali dengan karsinoma serviksneuroendokrin stadium IIIB dan hanya memilih perawatanpaliatif. Kasus kedua, perempuan 54 tahun, riwayat partuslima kali dengan karsinoma serviks neuroendokrin stadiumIIB. Pada pasien dilakukan terapi radiasi dan didapatkankondisi bebas penyakit selama 4 bulan. Terakhir, pasienperempuan 36 tahun riwayat partus dua kali dengankarsinoma serviks neuroendokrin stadium 1B1. Dilakukanhisterektomi radikal dan limfadenektomi kelenjar limfepelvis serta terapi radiasi. Kondisi pasien terkontrol dantidak terdapat kekambuhan setelah 15 tahun.Kesimpulan: Karsinoma serviks dengan jenis neuroendokrinharus dibedakan dengan keganasan lain pada daerah serviks.Uji imunohistokimia dapat digunakan untuk membedakanhal tersebut. Selain itu, penyusunan rencana tatalaksanauntuk mengatasi keganasan pada serviks juga harusmenjadi perhatian penting bagi klinisi. Direkomendasikanuntuk menerapkan tata laksana multimodal untuk mencapaihasil terapi yang optimal.Kata kunci: karsinoma serviks, karsinoma serviksneuroendokrin, tata laksana multimodal.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45006328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Water Intake during Pregnancy on Birth Weight","authors":"Tria Rosemiarti, Hardinsyah Hardinsyah, Budi I. Santoso, Sudung O. Pardede, Parlindungan Siregar, Netta M. Putri, Ratu S. Hanifah","doi":"10.32771/inajog.v11i3.1963","DOIUrl":"https://doi.org/10.32771/inajog.v11i3.1963","url":null,"abstract":"AbstractObjective: This systematic review aimed to investigate theeffect of water intake during pregnancy on infant birthweight.Methods: A comprehensive search was conducted usingthe keywords \"water intake,\" \"dehydration,\" \"pregnancy,\"\"outcome,\" \"hydration,\" \"birth weight,\" and \"birth outcome\"in databases such as \"SCOPUS,\" \"EBSCO,\" \"PUBMED,\"\"COCHRANE,\" and through \"Google Search.\" MeSH headings\"pregnancy\" and \"hydration\" were used for the search.Inclusion criteria encompassed pregnant women withoutpathological disorders, birth weight as a studied outcome,prospective cohorts, clinical trial study designs, and Englishlanguagepapers. Out of the 254 articles retrieved, six metthe specifi ed requirements and were included in this review.Results: The fi ndings from the six studies consistentlydemonstrated a positive correlation between higher waterintake, improved hydration, and increased birth weight.All studies measured water consumption or hydrationstatus between 8-37 weeks of gestation. Regardless of theduration of the studies, underhydration or low water intakewas consistently associated with lower birth weight.Conclusion: This review highlights that increasing waterintake among pregnant women positively affects infantbirth weight. Adequate water intake during pregnancy isrecommended to be in the range of 2180 – 3000 mL daily,considering hydration status and the stage of pregnancy.Keywords: birth weight, hydration, pregnancy, water intake.AbstrakTujuan: Untuk mengungkap pengaruh asupan air selamakehamilan terhadap berat lahir bayi.Metode: Menggunakan kata kunci “water intake,\"\"dehydration,\" \"pregnancy,\" \"outcome,\" \"hydration,\" \"birthweight,\" dan \"birth outcome,\", artikel dicari. Data diambil daridatabase \"SCOPUS,\" \"EBSCO,\" \"PUBMED,\" \"COCHRANE,\"dan \"Google Search\". Kami menggunakan MeSH headingskehamilan dan hidrasi untuk istilah pencarian. Kriteria inklusiadalah perempuan hamil tanpa kelainan patologis, beratbadan lahir adalah salah satu luaran penelitian, desain studiberupa kohort prospektif dan uji klinis, serta artikel dalambahasa Inggris. Dari 254 artikel yang diperoleh, enam artikelmemenuhi persyaratan dan digunakan untuk review ini.Hasil: Dari keenam penelitian menunjukkan bahwa semakintinggi asupan air, semakin baik hidrasi atau asupan airmeningkatkan berat bayi lahir. Semua penelitian mengukurkonsumsi air atau status hidrasi antara 8-37 minggu. Studistudiini secara konsisten memberikan bukti bahwa asupanair yang rendah atau kondisi kekurangan cairan dikaitkandengan berat badan lahir rendah, terlepas dari durasi studi.Kesimpulan: Kajian ini menunjukkan bahwa peningkatanasupan air ibu hamil berpengaruh positif terhadap beratlahir bayi. Asupan air yang cukup pada ibu hamil adalah2180 – 3000 mL setiap hari bergantung pada status hidrasidan usia kehamilan.Kata kunci: asupan air, berat lahir, hidrasi, kehamilan.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46181674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Vitamin D in Pregnant Women in Birth Weight of Neonates","authors":"Rajuddin Rajuddin, Derevie Hendryan Moulina, Munawar, Cut Meurah Yeni, Hilwah Nora","doi":"10.32771/inajog.v11i3.1896","DOIUrl":"https://doi.org/10.32771/inajog.v11i3.1896","url":null,"abstract":"Objective: To determine the relationship between serumvitamin D levels in third trimester mothers and newbornbirthttweight.Method: The study was conducted at the maternity wardof Dr. Zainoel Abidin General Hospital in Banda Aceh,Indonesia. Maternal and infant serum vitamin D levelswere measured using the Automatic ChemiluminescenceImmunoassay Analyzer (CLIA) method. Blood samples werecollected from mothers in the third trimester and frominfants after delivery. Spearman's correlation rank test wasemployed with a confi dence level of 95%. Vitamin D levelswere categorized as suffi cient, insuffi cient, and defi cient.Results: A total of 39 pregnant women with an averageage of 30.38 ± 6.21 years participated in the study, with apredominance of 38-39 weeks of gestation (35.9%). Themean vitamin D levels in mothers and neonates were 17.4ng/mL and 17.6 ng/mL, respectively (p = 0.003, R = 0.462).The average birth weight of the babies was 3,100 grams,ranging from 2,100 grams to 4,200 grams (p = 0.185, R =0.217). Both variables showed a positive correlation withvarying strength of the relationship.Conclusion: Maternal serum vitamin D levels in the thirdtrimester exhibited a positive correlation with serum vitaminD levels in neonates with moderate strength, but therewas no correlation with birth weight. The evaluation ofmaternal third-trimester serum vitamin D levels can serve asa predictor of neonatal vitamin D levels.Keywords: birth weight, neonates, pregnancy, vitamin D. \u0000AbstrakTujuan: Untuk menilai pengaruh hubungan kadar vitaminD serum ibu trimester ketiga terhadap kadar vitamin D danberat badan neonatus yang dilahirkan.Metode: Penelitian ini studi observasional korelatif dengandesain potong lintang yang dilakukan pada kamar bersalinRSUD dr. Zainoel Abidin Banda Aceh. Pengukuran kadarvitamin D serum ibu dan bayi dilakukan dengan metodeAutomatic Chemiluminescence Immunoassay Analyzer(CLIA). Analisis data dengan melakukan Uji Spearman’scorrelation rank test untuk menilai kekuatan hubungan duavariabel.Hasil: Sebanyak 39 ibu hamil usia 30,38 ± 6,21 tahun terlibatdalam penelitian ini dengan dominasi usia kehamilan 38–39minggu (35,9%). Rerata kadar vitamin D ibu dan bayi secaraberurutan adalah 17,4 ng/mL dan 17,6 ng/mL (p = 0,003,R = 0,462). Rerata berat badan bayi yang dilahirkan adalahsebesar 3.100 gram dengan rentang 2.100 gram hingga4.200 gram (p = 0,185, R = 0,217). Kedua variabel didapatkankorelasi positif dengan kekuatan hubungan bervariasi.Kesimpulan: Kadar vitamin D serum ibu trimester ketigaberkorelasi positif terhadap kadar vitamin D serum neonatusyang dilahirkan dengan kekuatan sedang namun tidakberkorelasi terhadap berat badan lahir bayi. Kadar vitaminD serum ibu pada trimester ketiga dapat dijadikan prediktorkadar vitamin D neonatus saat dilahirkan.Kata kunci: berat badan lahir, kehamilan, neonatus,vitamin D.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48314597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"9vHPV (Nonavalent) Vaccine Policy in Indonesia","authors":"Y. Hidayat, Gerry N. Reynaldi","doi":"10.32771/inajog.v11i2.1982","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1982","url":null,"abstract":"The Human papillomavirus (HPV) vaccine is the most common sexually transmitted infection worldwide. In Indonesia, cervical cancer is the second most common cancer in women, and HPV infection is the main cause. The distribution of HPV vaccine serotypes in Indonesia according to a study by Utomo et al. showed that out of 11,224 women, the most prevalent infections were types 52, 16, 18, and 58. The nonavalent HPV vaccine consists of virus-like particles that trigger an immune response against fi ve additional high-risk HPV types (31, 33, 45, 52, and 58), in addition to the four types (6, 11, 16, and 18) protected by the quadrivalent vaccine. The vaccine works by triggering the production of antibodies that can fi ght against the targeted HPV virus, thus preventing HPV-related infections and diseases. The nonavalent HPV vaccine has the potential to accelerate the elimination of cervical cancer. The 90-70-90 strategy is a global target set by the World Health Organization (WHO) to achieve the elimination of cervical cancer by 2030. This target includes three main indicators: 90% of all women must be vaccinated against HPV, 70% of women infected with HPV must be treated, and 90% of women diagnosed with cervical cancer must receive appropriate treatment. Implementation of the 90-70-90 strategy is expected to accelerate the global elimination of cervical cancer and provide signi fi cant health bene fi ts for women worldwide.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44632919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect Knowledge and Attitude with Behaviour of HPV Vaccination in Women of Reproductive Age","authors":"B. Darmawan, B. J. Laihad, Frank M. M. Wagey","doi":"10.32771/inajog.v11i1.1736","DOIUrl":"https://doi.org/10.32771/inajog.v11i1.1736","url":null,"abstract":"To observe the association between knowledgeand attitude towards HPV vaccination with the behaviortowards HPV vaccination on reproductive woman inIndonesia.Methods: We conducted observational analytic studywith cross-sectional design. The study was conducted inobstetric and gynecologic outpatient clinic in Prof. Dr. R.D. Kandou General Hospital, Manado Indonesia throughJuly and August 2021. Reproductively active woman wereincluded as the subject. Univariate and bivariate analysiswere conducted in this study.Results: We included 364 reproductive woman. The majorityof the subject were 20-35 year-old woman (50.8%) and weremarried (61.3%). The majority of the subject (72.8%) havereceived information about HPV vaccination. We foundsignificant association between knowledge and attitudewith the OR of 5.57 (p=0.00). Knowledge and attitudeshowed significant association with eagerness towards HPVvaccination. However, knowledge and behavior did notshow any significant association towards HPV vaccinationbehavior.Conclusion: There is a significant association betweenknowledge and attitude of HPV vaccination with eagernesstoward HPV vaccination in reproductive women in Indonesia.Keywords: behavior, HPV vaccination, knowledge,reproductive women. \u0000Keywords: behavior, HPV vaccination, knowledge,reproductive women. \u0000AbstrakTujuan: Untuk mengetahui hubungan pengetahuan dansikap terhadap perilaku vaksinasi HPV pada perempuan usiareproduktif di RSUP Prof. DR. R. D. Kandou, Manado.Metode: Penelitian ini merupakan penelitian analitikobservasional dengan pengambilan subjek potong lintang.Penelitian dilakukan di unit pelayanan bagian Obstetri danGinekologi RSUP Prof. Dr. R. D. Kandou Manado pada Juli-Agustus 2021. Subjek penelitian merupakan perempuanusia reproduktif yang bersedia untuk mengikuti penelitianini. Analisis data akan dilakukan secara univariat dan bivariatserta dilaporkan pada penelitian ini.Hasil: Penelitian ini mencakup 364 perempuan dengan usiaproduktif. Mayoritas subjek merupakan perempuan denganusia 20-35 tahun (50,8%) dan sudah menikah (61,3%).Mayoritas subjek (72,8%) pernah mendapatkan informasivaksinasi HPV sebelumnya. Hubungan antara pengetahuandan sikap terhadap vaksinasi menunjukkan hasil yangsignifikan (p=0,00) dengan OR 5,57. Pengetahuan dansikap juga menunjukkan hubungan yang signifikan dengankesediaan vaksin (p<0,05). Pengetahuan dan sikap tidakmenunjukkan hubungan yang bermakna terhadap perilakuvaksin (p>0,05).Kesimpulan: Terdapat hubungan yang bermakna antarapengetahuan dan sikap dengan perilaku keinginan vaksinasiHPV pada perempuan usia reproduktif.Kata kunci: pengetahuan, perempuan usia reproduktif,sikap, Vaksinasi HPV. \u0000 ","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49249741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Anxiety Level and Premature Rupture of Membrane Incidence during COVID-19 Pandemic","authors":"Renasheva Alifia Nugraha, M. A. Bachnas, Istar Yuliadi","doi":"10.32771/inajog.v11i1.1692","DOIUrl":"https://doi.org/10.32771/inajog.v11i1.1692","url":null,"abstract":"Abstract \u0000Objective: To determine the association between anxiety level and premature rupture of membrane incidence during COVID-19 pandemic. \u0000Methods: This study was a case-control study. The subjects of this study were patients giving birth at RSUD Dr. Moewardi Surakarta Hospital and UNS Sukoharjo Hospital in June - October 2021. Sampling was done by the purposive sampling technique on 70 samples. Data were analyzed using the chi-square test and logistic regression test. \u0000Results: Characteristic data of the study samples found that most of the study samples was severe anxiety (40%). There was a significant association between the level of anxiety with PROM incident (p = 0.00), and pregnant women with severe anxiety had a risk of PROM of 3.761 times compared to pregnant women who were not anxious (OR=3.761). In multivariate analysis, it was found that the most influential variable on the incidence of premature rupture of membranes was the level of anxiety (p=0.001) compared to parity (p=0.155), employment status (0.193), and education level (0.576). \u0000Conclusion: There was a significant association between anxiety level and premature rupture of membranes incidence during the COVID-19 pandemic, and there was an increased risk of premature rupture of membranes in pregnant women with severe anxiety levels during the COVID-19 pandemic. \u0000Keywords: anxiety level; premature rupture of membrane; COVID-19 pandemic.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46078791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative Platelet-Lymphocyte Ratio as a Prognostic Factor of Epithelial Ovarian Cancer","authors":"J. Winata, B. J. Laihad, Frank M. M. Wagey","doi":"10.32771/inajog.v11i1.1738","DOIUrl":"https://doi.org/10.32771/inajog.v11i1.1738","url":null,"abstract":"Objective: To determine whether platelet-lymphocyte ratio can be a prognostic factor for epithelial ovarian cancer. Methods: This study was a retrospective cohort with analytical design, conducted in the Department of Obstetrics and Gynecology of Prof. Dr. R.D. Kandou Manado General Hospital from January – November 2020. The subjects were all patients with epithelial ovarian cancer who met the inclusion and exclusion criteria. Data analysis was conducted with Chi-square test.Results: 35 subjects were included in this study. Most subjects were 40-50 years and had a platelet-lymphocyte ratio of above 200. The mean platelet-lymphocyte ratio of the subjects with epithelial ovarian cancer was 244.663 +- 130.0234. Chi-square test showed a significant association between platelet-lymphocyte ratio and the ovarian cancer relapse (X2 = 14.464 p = 0.000) with RR=4.0Conclusion: There was a significant difference between platelet-lymphocyte ratio and the ovarian cancer relapse.Keywords: epithelial ovarian cancer, inflammatory marker, platelet-lymphocyte ratio, prognosis.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47685752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovarian Reservation in Women with Ovarian Endometriosis Cyst after Laparoscopic Cystectomy and Leuprorelin Acetate Administration","authors":"Reza F. Akhmad, Yuli Trisetiyono, I. E. K. Setiawan, B. Pramono, S. Hadijono, Inu Mulyantoro, E. Ambari","doi":"10.32771/inajog.v11i2.1815","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1815","url":null,"abstract":"Objective: To determine differences in ovarian reserve in women with ovarian endometrial cysts after laparoscopic cystectomy and leuprorelin acetate administrationMethods: Single cohort prospective pre and post-test design study with 25 research subjects. The independent variables were interventional laparoscopic cystectomy, and leuprorelin acetate administration. The dependent variable is ovarian reserve as measured by AMH levels.Results: The research subjects had a mean age of 31 years and a BMI of 23.55 kg/m2. There were 8 subjects with unilateral cysts and 17 subjects with bilateral cysts. Preoperative AMH levels had a median value of 1.32 ng/mL (0.88-5.13), postoperative AMH levels had a median value of 1.07 ng/mL (0.60-4.53), and postoperative AMH levels + Leuprorelin Acetate injection had a median value of 1.06 ng/mL (0.50-4.65). There was a significant difference between preoperative AMH and postoperative AMH (p<0.001). There was no significant difference between postoperative AMH and postoperative AMH + Leuprorelin Acetate injection (p=0.149). BMI has a relationship (p=0.048) with pre-operative AMH levels with a weak and opposite relationship (r= -0.399).Conclusion: There was a statistically significant 18.9% decrease between pre-operative post-operative AMH levels. Body Mass Index (BMI) and pre-operative AMH levels are associated with one another.Keywords: anti-müllerian hormone, leuprorelin acetate, ovarian cystectomy, ovarian reserve.AbstrakTujuan: Mengetahui perbedaan cadangan ovarium pada perempuan dengan kista endometrium ovarium setelah laparoskopi kistektomi dan injeksi leuprorelin asetat.Metode: Desain penelitian pre dan post-test prospektif kohort tunggal dengan 25 subjek penelitian. Variabel bebas adalah intervensi laparoskopi kistektomi, dan injeksi leuprorelin asetat. Variabel terikat adalah cadangan ovarium yang diukur dengan kadar AMH.Hasil: Subjek penelitian memiliki rerata usia 31 tahun dan IMT 23,55 kg/m2. Terdapat 8 subjek dengan kista unilateral, 17 subjek dengan kista bilateral. Kadar AMH praoperasi memiliki nilai median 1,32 ng/mL (0,88-5,13), kadar AMH pascaoperasi memiliki nilai median 1,07 ng/mL (0,60-4,53), dan kadar AMH pascaoperasi + injeksi Leuprorelin Asetat memiliki nilai median 1,06 ng/mL (0,50-4,65). Ada perbedaan yang signifikan antara AMH pra operasi dan AMH pascaoperasi (p<0,001). Tidak ada perbedaan bermakna antara AMH pascaoperasi dengan injeksi AMH + Leuprorelin Asetat pascaoperasi (p=0,149). IMT memiliki hubungan (p=0,048) dengan kadar AMH pra operasi dengan hubungan yang lemah dan berlawanan (r= -0,399).Kesimpulan: Terdapat penurunan 18,9% antara tingkat AMH pra-operasi dan tingkat AMH pasca-operasi yang signifikan secara statistik. Ada hubungan antara BMI dan tingkat AMH pra-operasiKata kunci: cadangan ovarium, hormon anti-müllerian, kistektomi ovarium, leuprorelin asetat.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44394646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Wound Dehiscence Treatment","authors":"R. H. Kurniawan, Ni Putu C. D. Atmantika, A. K. Harzif, D. Nilasari","doi":"10.32771/inajog.v11i2.1847","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1847","url":null,"abstract":"Objective: This article describes management of surgicalwound dehiscence. in a cesarean section.Method: Case report.Case: A 39 years-old woman, P4, presented with reddish puscoming out from open surgical wound on day 4 following acaesarean section. Laboratory fi ndings revealed a conditionof Hypoalbuminemia, leukocytosis, and a Staphylococcusaureus was detected on pus from the wound base. Upon theresuturing, the wound was dressed with antimicrobial wounddressings and pad and changed every 12 hours. After 3 days,the wound was dressed with modern antimicrobial wounddressings gel and pad, changed every 3 days and plannedfor necrotomy afterwards. A presence of dry, granulationtissue was observed before the resuturing.Conclusion: Selection of dressing regimen shouldbe individualized according to the wounds. Modernantimicrobial wound dressing can be a good therapy optionfor surgical wound dehiscence after caesarean section.Keywords: surgical site infection, surgical wound, wounddehiscence.Tujuan: Artikel ini melaporkan tata laksana dehisensi lukaoperasi seksio sesarea.Metode: Laporan kasus.Kasus: Seorang perempuan 39 tahun, P4, datang dengankeluhan nanah kemerahan keluar dari luka operasi terbukapostoperasi seksio sesarea hari ke-4. Temuan laboratorium:Hipoalbuminemia, leukositosis, dan Staphylococcusaureus dari kultur dasar luka. Sebelum operasi penjahitankembali, luka dibalut dengan pembalut dan bantalan lukaantimikroba modern yang diresapi dengan hidrogel, digantisetiap 12 jam. Setelah 3 hari, luka dibalut dengan gel danpembalut luka antimikroba modern yang diresapi denganhidrogel, diganti setiap 3 hari dan direncanakan untuknekrotomi. Sebelum operasi dilakukan kembali, luka tampakkering dengan dasar jaringan granulasi.Kesimpulan: Regimen pembalutan harus disesuaikandengan kebutuhan masing-masing luka. Pembalut lukaantimikroba modern dapat menjadi pilihan terapi yang baikuntuk dehisensi luka bedah setelah operasi seksio sesarea.Kata kunci: dehisensi luka, infeksi luka operasi, luka operasi.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48179376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}