Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1803
G. B. Nugraha, N. W. P. Anggraini
Objectives: To explain that mode of delivery has a correlation with neonatal outcomes in preterm pregnancies.Methods: This study is a retrospective cohort conducted at Dr. Moewardi Surakarta Hospital, with total sampling of 484 cases divided into early preterm and late preterm from 2019 to 2021. Bivariate analysis was carried out to determine the correlation between Mode of Delivery (MOD) and neonatal outcomes.Results: In the early preterm group, mode of delivery had a significant correlation (p<0.05) with birth weight, APGAR score, and neonatal mortality, however a significant correlation (p<0.05) in the late preterm group was only found in the APGAR score and neonatal mortality outcomes. Cesarean delivery, in both early and late preterm births had a lower rate of asphyxia and neonatal death (p<0.05).Conclusion: There is a significant correlation between mode of delivery and neonatal outcomes in preterm birth. Caesarean delivery by indication can significantly reduce the risk of asphyxia, and neonatal mortality due to premature birth.Keywords: mode of delivery, neonatal outcome, preterm.AbstrakTujuan: Menjelaskan bahwa metode persalinan sangat berkorelasi dengan luaran neonatus pada kehamilan prematur, oleh karena itu penelitian ini dapat menjadi bahan pertimbangan untuk memilih metode persalinan.Metode: Penelitian ini merupakan penelitian kohort retrospektif yang dilakukan di RSUD Dr. Moewardi Surakarta, dengan total sampling sebanyak 484 kasus yang terbagi menjadi early preterm dan late preterm dari tahun 2019 hingga 2021. Analisis bivariat dilakukan dengan menggunakan analisis Chi-square dan Kruskal-Wallis untuk melihat korelasi antara metode persalinan (MOD) dan luaran neonatusHasil: Pada kelompok early preterm, metode persalinan memiliki hubungan yang signifikan (p<0,05) dengan luaran neonatus baik berat lahir, skor APGAR, dan kematian neonatus. Pada kelompok late preterm, hubungan yang signifikan (p<0,05) hanya didapatkan pada luaran skor APGAR dan kematian neonatus. Persalinan Caesar baik early maupun late preterm memiliki angka yang lebih rendah terhadap asfiksia dan kematian neonatus (p<0,05).Kata kunci: metode persalinan, luaran neonatus, preterm.
{"title":"Mode of Delivery and Neonatal Outcomes in Preterm Pregnancy","authors":"G. B. Nugraha, N. W. P. Anggraini","doi":"10.32771/inajog.v11i2.1803","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1803","url":null,"abstract":"Objectives: To explain that mode of delivery has a correlation with neonatal outcomes in preterm pregnancies.Methods: This study is a retrospective cohort conducted at Dr. Moewardi Surakarta Hospital, with total sampling of 484 cases divided into early preterm and late preterm from 2019 to 2021. Bivariate analysis was carried out to determine the correlation between Mode of Delivery (MOD) and neonatal outcomes.Results: In the early preterm group, mode of delivery had a significant correlation (p<0.05) with birth weight, APGAR score, and neonatal mortality, however a significant correlation (p<0.05) in the late preterm group was only found in the APGAR score and neonatal mortality outcomes. Cesarean delivery, in both early and late preterm births had a lower rate of asphyxia and neonatal death (p<0.05).Conclusion: There is a significant correlation between mode of delivery and neonatal outcomes in preterm birth. Caesarean delivery by indication can significantly reduce the risk of asphyxia, and neonatal mortality due to premature birth.Keywords: mode of delivery, neonatal outcome, preterm.AbstrakTujuan: Menjelaskan bahwa metode persalinan sangat berkorelasi dengan luaran neonatus pada kehamilan prematur, oleh karena itu penelitian ini dapat menjadi bahan pertimbangan untuk memilih metode persalinan.Metode: Penelitian ini merupakan penelitian kohort retrospektif yang dilakukan di RSUD Dr. Moewardi Surakarta, dengan total sampling sebanyak 484 kasus yang terbagi menjadi early preterm dan late preterm dari tahun 2019 hingga 2021. Analisis bivariat dilakukan dengan menggunakan analisis Chi-square dan Kruskal-Wallis untuk melihat korelasi antara metode persalinan (MOD) dan luaran neonatusHasil: Pada kelompok early preterm, metode persalinan memiliki hubungan yang signifikan (p<0,05) dengan luaran neonatus baik berat lahir, skor APGAR, dan kematian neonatus. Pada kelompok late preterm, hubungan yang signifikan (p<0,05) hanya didapatkan pada luaran skor APGAR dan kematian neonatus. Persalinan Caesar baik early maupun late preterm memiliki angka yang lebih rendah terhadap asfiksia dan kematian neonatus (p<0,05).Kata kunci: metode persalinan, luaran neonatus, preterm.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48533032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1892
O. Madjid, Simon Fongana, D. Ocviyanti, J. Indarti, S. Adjie, I. Kayika, A. Pusponegoro, S. R. F. Harun
Objective: To determine the effect of clinical governance in PHCs on maternal and perinatal health in Banten Province, Indonesia.Methods: This was an observational analytic study with cross sectional method performed on the PHCs on Banten Province, Indonesia. All PHCs in Banten Province having maternal and perinatal health services were included in the study. Clinical governance and services were measured using a self-made questionnaire filled by the representative of the PHC. Characteristics analyzed in this study were age, education level, completed training, and occupation. Clinical governance aspects analyzed in this study were leadership, culture, competence, governance, and readiness. The services analyzed in this study were antenatal, pathology, and emergency service. Results: There were 117 PHC representatives who were recruited to the study. The PHC which were categorized as “outstanding” for leadership, culture, competence, governance, and readiness were 23.1%, 41%, 98%, 81.2%, and 83.8%, respectively. The PHC which were categorized as having “good” antenatal, pathology, and emergency services were 92.3%, 51.3%, and 90.6%, respectively. The PHCs with better clinical governance aspects delivered better antenatal, pathology, and emergency services for maternal and perinatal care.Conclusions: Primary health cares with better clinical governance aspects delivered better antenatal, pathology, and emergency services for maternal and perinatal care. Therefore, improving clinical governance is essential to improve maternal and perinatal health services quality in Banten Province, IndonesiaKeywords: clinical governance, health service, maternal health, quality assurance.AbstrakTujuan: Untuk mengetahui pengaruh tata kelola klinik di Puskesmas terhadap kesehatan ibu dan perinatal di Provinsi Banten, Indonesia.Metode: Penelitian observasional analitik dengan metode potong lintang yang dilakukan di Puskesmas di Provinsi Banten, Indonesia. Semua Puskesmas di Provinsi Banten yang memiliki layanan kesehatan ibu dan perinatal diikutsertakan dalam penelitian ini. Tata kelola dan layanan klinis diukur menggunakan kuesioner buatan sendiri yang diisi oleh perwakilan Puskesmas. Karakteristik yang dianalisis dalam penelitian ini adalah usia, tingkat pendidikan, pelatihan yang diselesaikan, dan pekerjaan. Aspek tata kelola klinis yang dianalisis dalam penelitian ini adalah kepemimpinan, budaya, kompetensi, tata kelola, dan kesiapan. Pelayanan yang dianalisis dalam penelitian ini adalah pelayanan antenatal, patologi, dan gawat darurat.Hasil: Terdapat 117 perwakilan Puskesmas yang direkrut untuk penelitian. Puskesmas yang dikategorikan “sangat baik” untuk kepemimpinan, budaya, kompetensi, tata kelola, dan kesiapan masing-masing adalah 23,1%, 41%, 98%, 81,2%, dan 83,8%. Puskesmas yang memiliki pelayanan antenatal, patologi, dan gawat darurat yang tergolong “baik” berturut-turut adalah 92,3%, 51,3%, dan 90,6%. Puskesmas dengan aspek tata kelola klinis yang le
{"title":"Qualitative Study on Maternal and Perinatal Health Services in Primary Health Care Facility in Banten Province","authors":"O. Madjid, Simon Fongana, D. Ocviyanti, J. Indarti, S. Adjie, I. Kayika, A. Pusponegoro, S. R. F. Harun","doi":"10.32771/inajog.v11i2.1892","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1892","url":null,"abstract":"\u0000 \u0000 \u0000Objective: To determine the effect of clinical governance in PHCs on maternal and perinatal health in Banten Province, Indonesia.Methods: This was an observational analytic study with cross sectional method performed on the PHCs on Banten Province, Indonesia. All PHCs in Banten Province having maternal and perinatal health services were included in the study. Clinical governance and services were measured using a self-made questionnaire filled by the representative of the PHC. Characteristics analyzed in this study were age, education level, completed training, and occupation. Clinical governance aspects analyzed in this study were leadership, culture, competence, governance, and readiness. The services analyzed in this study were antenatal, pathology, and emergency service. Results: There were 117 PHC representatives who were recruited to the study. The PHC which were categorized as “outstanding” for leadership, culture, competence, governance, and readiness were 23.1%, 41%, 98%, 81.2%, and 83.8%, respectively. The PHC which were categorized as having “good” antenatal, pathology, and emergency services were 92.3%, 51.3%, and 90.6%, respectively. The PHCs with better clinical governance aspects delivered better antenatal, pathology, and emergency services for maternal and perinatal care.Conclusions: Primary health cares with better clinical governance aspects delivered better antenatal, pathology, and emergency services for maternal and perinatal care. Therefore, improving clinical governance is essential to improve maternal and perinatal health services quality in Banten Province, IndonesiaKeywords: clinical governance, health service, maternal health, quality assurance.AbstrakTujuan: Untuk mengetahui pengaruh tata kelola klinik di Puskesmas terhadap kesehatan ibu dan perinatal di Provinsi Banten, Indonesia.Metode: Penelitian observasional analitik dengan metode potong lintang yang dilakukan di Puskesmas di Provinsi Banten, Indonesia. Semua Puskesmas di Provinsi Banten yang memiliki layanan kesehatan ibu dan perinatal diikutsertakan dalam penelitian ini. Tata kelola dan layanan klinis diukur menggunakan kuesioner buatan sendiri yang diisi oleh perwakilan Puskesmas. Karakteristik yang dianalisis dalam penelitian ini adalah usia, tingkat pendidikan, pelatihan yang diselesaikan, dan pekerjaan. Aspek tata kelola klinis yang dianalisis dalam penelitian ini adalah kepemimpinan, budaya, kompetensi, tata kelola, dan kesiapan. Pelayanan yang dianalisis dalam penelitian ini adalah pelayanan antenatal, patologi, dan gawat darurat.Hasil: Terdapat 117 perwakilan Puskesmas yang direkrut untuk penelitian. Puskesmas yang dikategorikan “sangat baik” untuk kepemimpinan, budaya, kompetensi, tata kelola, dan kesiapan masing-masing adalah 23,1%, 41%, 98%, 81,2%, dan 83,8%. Puskesmas yang memiliki pelayanan antenatal, patologi, dan gawat darurat yang tergolong “baik” berturut-turut adalah 92,3%, 51,3%, dan 90,6%. Puskesmas dengan aspek tata kelola klinis yang le","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48047613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1873
Venkatesha K. Vasudevamurthy, Rashmi S Desai, Ashwini H. Rmaswamy, Kasturi V. Donimath, Divyashree Bhat
Objective: To assess the perceptions and intentions of pregnant women regarding COVID-19 vaccination and to explore the reasons for vaccine hesitancy as well as acceptance. Methods: This prospective cross-sectional study was conducted in tertiary care hospital in Karnataka. Around 811 pregnant women attending the antenatal clinic were recruited into the study. Data were collected using a face-to-face, anonymous questionnaire written in local language.Results: Eighty six point two percent participants were aged 20 to 30 years and 64.6% had completed their schooling. 94.3% of them were homemakers and 58 % of the participants were in their third trimester. 65.5% of study group members lived in a COVID-supportive environment. Participants with COVID-19 vaccination awareness accounted for 87.4% and 65.4% were willing to receive the same whole heartedly. Our study found that 65.4% of participants were willing to receive covid-19 vaccine. The reasons for refusal were Lack of sufficient information regarding the vaccine, may be harmful to foetus and mother and lack of data proving its quality and efficiency.Conclusion: Pregnant women in the North Karnataka region were highly receptive to COVID-19 immunization. Although a high level of awareness was apparent, the lack of data and fear of side effects were two major concerns for refusal. Confidence in the government and the availability of free vaccines for all have demonstrated a massive impact on vaccination. Keywords: antenatal, covid-19, pregnancy, vaccination.AbstrakTujuan: Menilai persepsi dan keinginan perempuan hamil terkait vaksin COVID-19 dan alasan terkait penerimaan dan juga keraguan terhadap vaksin.Metode: Penelitian ini merupakan penelitian potong lintang dengan pendekatan prospektif yang dilakukan di Rumah Sakit Karnataka. Perempuan hamil sebanyak 811 menjadi subjek penelitian. Data dikumpulkan menggunakan kuesioner yang dituliskan dalam Bahasa lokal dan pengumpulan data dilakukan secara tatap muka. Hasil: Sebanyak 86,2 % sampel penelitian berusia 20 hingga 30 tahun dan 64,6% telah lulus sekolah. Sebanyak 94,3% sampel adalah ibu rumah tangga dan 58% dari sampel dengan usia kehamilan pada trimester ketiga. Sebanyak 65,5% grup tinggal pada kondisi. Sebanyak 87,4% sampel sadar akan keutamaan vaksin dan 65,4% bersedia mendapatkan vaksin. Alasan penolakan terhadap vaksin adalah kurangnya pengetahun mengenai vaksin dan ketakutan akan efek sampingnya.Kesimpulan: Perempuan hamil di Karnatakan Utara terbuka terhadap imunisasi COVID-19. Disamping tingginya angka kesadaran akan imunisasi COVID-19, penolakan umumnya didominasi akibat kurangnya pengetahuan dan ketakutan akan efek samping. Keyakinan pada pemerintah dan ketersediaan vaksin secara gratis sangat berpengaruh pada vaksinasi.Kata kunci: antenatal. covid-19, kehamilan, vaksinasi.
目的:了解孕妇对COVID-19疫苗接种的认知和意向，探讨疫苗犹豫和接受的原因。方法:本前瞻性横断面研究在卡纳塔克邦三级医院进行。约有811名孕妇参加了产前诊所的研究。数据收集采用面对面，匿名问卷，以当地语言撰写。结果:86.2%的参与者年龄在20至30岁之间，64.6%的参与者完成了学业。其中94.3%是家庭主妇，58%的参与者处于妊娠晚期。65.5%的学习小组成员生活在支持新冠病毒的环境中。知晓新冠肺炎疫苗接种的参与者占87.4%，愿意全心全意接受疫苗接种的参与者占65.4%。我们的研究发现，65.4%的参与者愿意接种covid-19疫苗。拒绝的理由是缺乏关于疫苗的充分信息，可能对胎儿和母亲有害，以及缺乏证明其质量和效率的数据。结论:北卡纳塔克邦孕妇对COVID-19免疫的接受度较高。虽然显然有高度的认识，但缺乏数据和担心副作用是拒绝的两个主要问题。对政府的信心和所有人都能获得免费疫苗，对疫苗接种产生了巨大影响。关键词:产前，covid-19，妊娠，疫苗接种【摘要】图juan:新冠肺炎新冠病毒在中国流行病学研究中的应用，在中国流行病学研究中的应用，在中国流行病学研究中的应用方法:Penelitian ini merupakan Penelitian poong lintang dengan pendekatan前景yang dilakukan di Rumah Sakit Karnataka。Perempuan hamil sebanyak 811 menjadi subjek penelitian。数据统计，孟古纳坎，巴哈萨，巴哈萨，巴哈萨，当地丹，彭普兰，数据统计，孟古纳坎。Hasil: Sebanyak 86, 2%样本penelitian berusia 20 hingga 30 tahun dan 64,6% telah lulus sekolah。Sebanyak 94,3% sampel adalah ibu rumah tangga dan 58% dari sampel dengan usia kehamilan pada trimester ketiga。Sebanyak 65,5%的group tinggal padadkondisi。Sebanyak 87,4% sampel sadar akan keutamaan vaksin 65,4% bersedia mendapatkan vaksin。Alasan penolakan terhadap vakin adalah kurangnya pengetahun mengenai vakin dan ketakutan akan efek sampingnya。卡纳塔克邦:我的祖国，我的祖国，我的祖国，我的祖国，我的祖国，我的祖国。消除新冠肺炎，预防禽流感，预防禽流感，预防禽流感，预防禽流感，预防禽流感，预防禽流感，预防禽流感，预防禽流感，预防禽流感，预防禽流感。我是说，我是说，我是说，我是说，我是说，我是说，我是说，我是说，我是说，我是说。Kata kunci:产前。Covid-19，克哈米兰，瓦克西纳西。
{"title":"Attitude towards COVID-19 Vaccine among Pregnant Women","authors":"Venkatesha K. Vasudevamurthy, Rashmi S Desai, Ashwini H. Rmaswamy, Kasturi V. Donimath, Divyashree Bhat","doi":"10.32771/inajog.v11i2.1873","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1873","url":null,"abstract":"Objective: To assess the perceptions and intentions of pregnant women regarding COVID-19 vaccination and to explore the reasons for vaccine hesitancy as well as acceptance. Methods: This prospective cross-sectional study was conducted in tertiary care hospital in Karnataka. Around 811 pregnant women attending the antenatal clinic were recruited into the study. Data were collected using a face-to-face, anonymous questionnaire written in local language.Results: Eighty six point two percent participants were aged 20 to 30 years and 64.6% had completed their schooling. 94.3% of them were homemakers and 58 % of the participants were in their third trimester. 65.5% of study group members lived in a COVID-supportive environment. Participants with COVID-19 vaccination awareness accounted for 87.4% and 65.4% were willing to receive the same whole heartedly. Our study found that 65.4% of participants were willing to receive covid-19 vaccine. The reasons for refusal were Lack of sufficient information regarding the vaccine, may be harmful to foetus and mother and lack of data proving its quality and efficiency.Conclusion: Pregnant women in the North Karnataka region were highly receptive to COVID-19 immunization. Although a high level of awareness was apparent, the lack of data and fear of side effects were two major concerns for refusal. Confidence in the government and the availability of free vaccines for all have demonstrated a massive impact on vaccination. Keywords: antenatal, covid-19, pregnancy, vaccination.AbstrakTujuan: Menilai persepsi dan keinginan perempuan hamil terkait vaksin COVID-19 dan alasan terkait penerimaan dan juga keraguan terhadap vaksin.Metode: Penelitian ini merupakan penelitian potong lintang dengan pendekatan prospektif yang dilakukan di Rumah Sakit Karnataka. Perempuan hamil sebanyak 811 menjadi subjek penelitian. Data dikumpulkan menggunakan kuesioner yang dituliskan dalam Bahasa lokal dan pengumpulan data dilakukan secara tatap muka. Hasil: Sebanyak 86,2 % sampel penelitian berusia 20 hingga 30 tahun dan 64,6% telah lulus sekolah. Sebanyak 94,3% sampel adalah ibu rumah tangga dan 58% dari sampel dengan usia kehamilan pada trimester ketiga. Sebanyak 65,5% grup tinggal pada kondisi. Sebanyak 87,4% sampel sadar akan keutamaan vaksin dan 65,4% bersedia mendapatkan vaksin. Alasan penolakan terhadap vaksin adalah kurangnya pengetahun mengenai vaksin dan ketakutan akan efek sampingnya.Kesimpulan: Perempuan hamil di Karnatakan Utara terbuka terhadap imunisasi COVID-19. Disamping tingginya angka kesadaran akan imunisasi COVID-19, penolakan umumnya didominasi akibat kurangnya pengetahuan dan ketakutan akan efek samping. Keyakinan pada pemerintah dan ketersediaan vaksin secara gratis sangat berpengaruh pada vaksinasi.Kata kunci: antenatal. covid-19, kehamilan, vaksinasi.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45313826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1884
N. Nurhayati, Suhermi S, S. H. Hamang
bjective: To determine the effect of the duration of using Depo Medroxyprogesterone Acetate (DMPA) on the Menstrual Cycle.Methods: This research is an analytical study of 102 patients who used DMPA for less than 1 year and more than 1 year and then analyzed the types of menstrual disorders experienced while using DMPA contraception at RSIA Masyita Makassar Tahun 2022. Data collection was carried out by direct observation at RSIA. Masyita was then arranged in a checklist that has been prepared.Data is processed using SPSS version 25.0. Results: There is a significant effect between the length of use of Depo Medroxyprogesterone Acetate (DMPA) and the Menstrual Cycle (p=0.000).Conclusion: There are long-term effects of using DMPA on menstrual cycle disorders, the most common one is hypermenorrhea. These results showed that the use of Depo Medroxyprogesterone Acetate (DMPA) for more than 1 year has shown many effects on Menstrual Disorders hence can be used by midwives to provide knowledge to use in the counseling session to patients who wishes to use DMPA regarding the side effects and risks of using longer contraceptives.Keywords: Depo Medroxyprogesterone Acetate (DMPA), duration of use, menstrual cycle.AbstrakObjektif: Untuk mengetahui pengaruh lama penggunaan Depo Medroksiprogesteron Asetat (DMPA) terhadap siklus menstruasi.Metode: Penelitian ini merupakan jenis penelitian analitik terhadap 102 pasien yang menggunakan DMPA kurang dari 1 tahun dan lebih dari 1 tahun kemudian dianalisis jenis gangguan menstruasi yang dialami selama menggunakan kontrasepsi DMPA di RSIA Masyita Makassar. Pengumpulan data dilakukan dengan metode observasi langsung di RSIA Tahun 2022. Masyita kemudian disusun dalam checklist yang telah disiapkan.Data diolah menggunakan SPSS versi 25.0.Hasil: Ada pengaruh yang signifikan antara lama penggunaan Depo Medroksiprogesteron Asetat (DMPA) dengan siklus menstruasi (p=0,000).Kesimpulan: Adanya Efek dari Jangka Panjang Penggunaan DMPA terhadap gangguan siklus Mentsruasi yang terbanyak yaitu Hipermenore. Hasil ini menunjukkan bahwaPenggunaan Depo Medroksiprogesteron Asetat (DMPA) selama lebih dari 1 tahun telah menunjukkan banyak efek pada gangguan menstruasi dan selanjutnya dapat digunakan oleh bidan dalam memberikan pengetahuan dan konseling kepada pasien yang akan menggunakan DMPA mengenai efek samping dan resiko penggunaan kontrasepsi yang lebih lama.Kata kunci: Depo Medroksiprogesteron Asetat (DMPA), lama pemakaian, siklus menstruasi.
目的:探讨醋酸甲羟孕酮(Depo me羟孕酮，DMPA)使用时间对月经周期的影响。方法:本研究对102例使用DMPA少于1年和超过1年的患者进行分析研究，分析在2022年Masyita Makassar Tahun RSIA使用DMPA避孕时出现的月经失调类型。数据收集在RSIA通过直接观察进行。然后将Masyita安排在已准备好的清单中。数据使用SPSS 25.0版本进行处理。结果:醋酸甲羟孕酮(Depo me羟孕酮，DMPA)使用时间与月经周期有显著影响(p=0.000)。结论:DMPA对月经周期紊乱有远期疗效，以月经过多最为常见。这些结果表明，使用醋酸甲孕酮(DMPA)超过1年已显示出对月经紊乱的许多影响，因此助产士可以使用它向希望使用DMPA的患者提供有关使用更长时间避孕药的副作用和风险的知识。关键词:醋酸甲羟孕酮(DMPA)，用药时间，月经周期【摘要】目的:复方丹参多糖(DMPA)治疗月经初潮的疗效。方法:penytian ini merupakan jenis Penelitian analitik terhadap 102 pasien yang menggunakan DMPA kurang dari 1 tahun dan lebih dari 1 tahun kemudian diananalysis jenis gangguan月经，yang dialami selama menggunakan kontrasepsi DMPA di RSIA Masyita Makassar。彭普兰的数据是由拉库坎登干方法观测到的。Masyita kemudian dissusun dalam checklist yang telah disiapkan。数据统计用SPSS 25.0版。哈西尔:Ada pengaruh yang signifikan antara lama penggunaan Depo medroksi孕激素Asetat (DMPA) dengan siklus月经(p= 0000)。Adanya Efek dari Jangka Panjang Penggunaan DMPA terhadap gangguan siklus Mentsruasi yang terbanyak yitu Hipermenore。Hasil ini menunjukkan bahwaPenggunaan Depo Medroksiprogesteron Asetat (DMPA) selama lebih达里语1 tahun telah menunjukkan banyak efek篇gangguan menstruasi丹selanjutnya dapat digunakan oleh pokalchuk bidan dalam memberikan pengetahuan丹konseling kepada pasien杨阿坎人menggunakan DMPA mengenai efek取样丹resiko penggunaan kontrasepsi杨lebih喇嘛。Kata kunci: Depo medroksipro孕酮Asetat (DMPA)， lama pemakaian, siklus月经。
{"title":"Depo Medroxyprogesterone Acetate (DMPA): Long-Term Effects on Menstrual Cycle Disorders","authors":"N. Nurhayati, Suhermi S, S. H. Hamang","doi":"10.32771/inajog.v11i2.1884","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1884","url":null,"abstract":"bjective: To determine the effect of the duration of using Depo Medroxyprogesterone Acetate (DMPA) on the Menstrual Cycle.Methods: This research is an analytical study of 102 patients who used DMPA for less than 1 year and more than 1 year and then analyzed the types of menstrual disorders experienced while using DMPA contraception at RSIA Masyita Makassar Tahun 2022. Data collection was carried out by direct observation at RSIA. Masyita was then arranged in a checklist that has been prepared.Data is processed using SPSS version 25.0. Results: There is a significant effect between the length of use of Depo Medroxyprogesterone Acetate (DMPA) and the Menstrual Cycle (p=0.000).Conclusion: There are long-term effects of using DMPA on menstrual cycle disorders, the most common one is hypermenorrhea. These results showed that the use of Depo Medroxyprogesterone Acetate (DMPA) for more than 1 year has shown many effects on Menstrual Disorders hence can be used by midwives to provide knowledge to use in the counseling session to patients who wishes to use DMPA regarding the side effects and risks of using longer contraceptives.Keywords: Depo Medroxyprogesterone Acetate (DMPA), duration of use, menstrual cycle.AbstrakObjektif: Untuk mengetahui pengaruh lama penggunaan Depo Medroksiprogesteron Asetat (DMPA) terhadap siklus menstruasi.Metode: Penelitian ini merupakan jenis penelitian analitik terhadap 102 pasien yang menggunakan DMPA kurang dari 1 tahun dan lebih dari 1 tahun kemudian dianalisis jenis gangguan menstruasi yang dialami selama menggunakan kontrasepsi DMPA di RSIA Masyita Makassar. Pengumpulan data dilakukan dengan metode observasi langsung di RSIA Tahun 2022. Masyita kemudian disusun dalam checklist yang telah disiapkan.Data diolah menggunakan SPSS versi 25.0.Hasil: Ada pengaruh yang signifikan antara lama penggunaan Depo Medroksiprogesteron Asetat (DMPA) dengan siklus menstruasi (p=0,000).Kesimpulan: Adanya Efek dari Jangka Panjang Penggunaan DMPA terhadap gangguan siklus Mentsruasi yang terbanyak yaitu Hipermenore. Hasil ini menunjukkan bahwaPenggunaan Depo Medroksiprogesteron Asetat (DMPA) selama lebih dari 1 tahun telah menunjukkan banyak efek pada gangguan menstruasi dan selanjutnya dapat digunakan oleh bidan dalam memberikan pengetahuan dan konseling kepada pasien yang akan menggunakan DMPA mengenai efek samping dan resiko penggunaan kontrasepsi yang lebih lama.Kata kunci: Depo Medroksiprogesteron Asetat (DMPA), lama pemakaian, siklus menstruasi.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46458426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1791
Radiva H. Mazaya, J. Dewantiningrum, F. A. Rahmadi, D. T. Anantyo
ltrasound parameters during pregnancy and the growth of children aged 2 – 3 years.Methods: This was an analytic observational study with a longitudinal approach using data from the first 1,000 days of life. Study conducted at the Faculty of Medicine, Diponegoro University. The research subjects were children aged 2 – 3 years old with good nutritional status and democratic parenting from 14 City Health Centers in Semarang. The ultrasound parameters obtained were Biparietal Diameter (BPD), Abdomen Circumference (AC), Head Circumference (HC), Femur Length (FL) at 20 – 24 weeks of gestation. Data were obtained during the second trimester. Data on the growth of children at the age of 2 years obtained are height, weight, and HC. Statistical test using Pearson correlation test, with p<0.1 is considered significant.Results: The level of confidence used in this study was 90% and obtained 45 research subjects with a female gender of 26 children (57.8%) and 19 male children (42.2%). The Pearson test showed that there was no significant relationship between BPD and height (p=0.18; r=-0.20), AC and height (p=0.12; r=-0.23), and FL and height (p=0.17; r=-0.20). There was a significant relationship between HC and height (p=0.04; r=-0.29), BPD and weight (p=0.06; r=-0.28), HC and weight (p=0.01; r=-0,.5), AC and weight (p=0.08; r=-0.26), FL and weight (p=0.05; r=-0.29) and prenatal HC and postnatal HC (p=0.03; r=-0.32).Conclusion: There is a significant relationship between ultrasound parameters during pregnancy and the growth of children aged 2 – 3 years.Keywords: abdominal circumference, biparietal diameter, child growth, femur length, head circumference, pregnancy.AbstrakTujuan: Untuk mengetahui hubungan antara parameter ultrasonografi saat kehamilan dengan pertumbuhan anak usia 2-3 tahun.Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan longitudinal menggunakan data penelitian 1.000 hari pertama kehidupan yang dilakukan di Fakultas Kedokteran Universitas Diponegoro. Subjek penelitian adalah anak usia 2 – 3 tahun dengan gizi baik dan pola asuh demokratis dari 14 Puskesmas Kota Semarang. Parameter USG yang diperoleh adalah diameter biparietal (BPD), lingkar abdomen (AC), lingkar kepala (HC), dan panjang femur (FL) pada usia kehamilan 20 – 24 minggu. Data diperoleh selama trimester kedua. Data tumbuh kembang anak usia 2 tahun yang diperoleh adalah tinggi badan, berat badan, dan lingkar kepala. Uji statistik menggunakan uji korelasi Pearson, dengan p<0,1 dianggap signifikan.Hasil: Tingkat kepercayaan yang digunakan dalam penelitian ini adalah 90% dan diperoleh 45 subjek penelitian dengan jenis kelamin perempuan 26 anak (57,8%) dan 19 anak laki-laki (42,2%). Uji Pearson menunjukkan bahwa tidak ada hubungan yang signifikan antara BPD dengan tinggi badan (p=0,18; r=-0,20), AC dan tinggi badan (p=0,12; r=-0,23), dan FL dan tinggi (p=0,17; r=-0,20). Terdapat hubungan yang signifikan antara HC dengan tinggi badan (p=0,04; r=-0,29), B
{"title":"In Utero Ultrasonography Parameters as a Children Growth Prediction at Age 2 – 3","authors":"Radiva H. Mazaya, J. Dewantiningrum, F. A. Rahmadi, D. T. Anantyo","doi":"10.32771/inajog.v11i2.1791","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1791","url":null,"abstract":"ltrasound parameters during pregnancy and the growth of children aged 2 – 3 years.Methods: This was an analytic observational study with a longitudinal approach using data from the first 1,000 days of life. Study conducted at the Faculty of Medicine, Diponegoro University. The research subjects were children aged 2 – 3 years old with good nutritional status and democratic parenting from 14 City Health Centers in Semarang. The ultrasound parameters obtained were Biparietal Diameter (BPD), Abdomen Circumference (AC), Head Circumference (HC), Femur Length (FL) at 20 – 24 weeks of gestation. Data were obtained during the second trimester. Data on the growth of children at the age of 2 years obtained are height, weight, and HC. Statistical test using Pearson correlation test, with p<0.1 is considered significant.Results: The level of confidence used in this study was 90% and obtained 45 research subjects with a female gender of 26 children (57.8%) and 19 male children (42.2%). The Pearson test showed that there was no significant relationship between BPD and height (p=0.18; r=-0.20), AC and height (p=0.12; r=-0.23), and FL and height (p=0.17; r=-0.20). There was a significant relationship between HC and height (p=0.04; r=-0.29), BPD and weight (p=0.06; r=-0.28), HC and weight (p=0.01; r=-0,.5), AC and weight (p=0.08; r=-0.26), FL and weight (p=0.05; r=-0.29) and prenatal HC and postnatal HC (p=0.03; r=-0.32).Conclusion: There is a significant relationship between ultrasound parameters during pregnancy and the growth of children aged 2 – 3 years.Keywords: abdominal circumference, biparietal diameter, child growth, femur length, head circumference, pregnancy.AbstrakTujuan: Untuk mengetahui hubungan antara parameter ultrasonografi saat kehamilan dengan pertumbuhan anak usia 2-3 tahun.Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan longitudinal menggunakan data penelitian 1.000 hari pertama kehidupan yang dilakukan di Fakultas Kedokteran Universitas Diponegoro. Subjek penelitian adalah anak usia 2 – 3 tahun dengan gizi baik dan pola asuh demokratis dari 14 Puskesmas Kota Semarang. Parameter USG yang diperoleh adalah diameter biparietal (BPD), lingkar abdomen (AC), lingkar kepala (HC), dan panjang femur (FL) pada usia kehamilan 20 – 24 minggu. Data diperoleh selama trimester kedua. Data tumbuh kembang anak usia 2 tahun yang diperoleh adalah tinggi badan, berat badan, dan lingkar kepala. Uji statistik menggunakan uji korelasi Pearson, dengan p<0,1 dianggap signifikan.Hasil: Tingkat kepercayaan yang digunakan dalam penelitian ini adalah 90% dan diperoleh 45 subjek penelitian dengan jenis kelamin perempuan 26 anak (57,8%) dan 19 anak laki-laki (42,2%). Uji Pearson menunjukkan bahwa tidak ada hubungan yang signifikan antara BPD dengan tinggi badan (p=0,18; r=-0,20), AC dan tinggi badan (p=0,12; r=-0,23), dan FL dan tinggi (p=0,17; r=-0,20). Terdapat hubungan yang signifikan antara HC dengan tinggi badan (p=0,04; r=-0,29), B","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46845978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1733
S. Subandi, S. Purbadi
Objectives: To determine the anti-cancer effect of nanocurcumin on choriocarcinoma. Methods: This study observes the telomerase activity, NF-κ B expression, and BrdU proliferation index in cultures of BeWo choriocarcinoma cell line (ATCC CCL-98) exposed to MTX and nanocurcumin in various doses. The sample used in this study consisted of 4 groups of BeWo cells that received a combination of MTX and nanocurcumin, and 2 other groups for positive and negative control. Results: There was a decrease in telomerase activity, NF-κ B expression, and BrdU proliferation index in the 4 treatment groups compared to the negative and positive control group (p ≤ 0.05). Conclusion: Nanocurcumin and MTX decrease telomerase expression, NF-κ B expression, and the BrdU proliferation index in choriocarcinoma BeWo cell line culture faster than MTX alone.
{"title":"Effect of Nanocurcumin in Combination with Methotrexate on Telomerase Activity, NF-kb Expression, and Proliferation Index of Bewo Choriocarcinoma Cells","authors":"S. Subandi, S. Purbadi","doi":"10.32771/inajog.v11i2.1733","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1733","url":null,"abstract":"Objectives: To determine the anti-cancer effect of nanocurcumin on choriocarcinoma. Methods: This study observes the telomerase activity, NF-κ B expression, and BrdU proliferation index in cultures of BeWo choriocarcinoma cell line (ATCC CCL-98) exposed to MTX and nanocurcumin in various doses. The sample used in this study consisted of 4 groups of BeWo cells that received a combination of MTX and nanocurcumin, and 2 other groups for positive and negative control. Results: There was a decrease in telomerase activity, NF-κ B expression, and BrdU proliferation index in the 4 treatment groups compared to the negative and positive control group (p ≤ 0.05). Conclusion: Nanocurcumin and MTX decrease telomerase expression, NF-κ B expression, and the BrdU proliferation index in choriocarcinoma BeWo cell line culture faster than MTX alone.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46381587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1721
Alfa P. Meutia, B. Santoso, Suskhan Djusad
AbstractObjective: To review the advantage of PRP use on mesh-augmented surgery.Methods: Literature review of PRP application of mesh.Results: The application of PRP on mesh shows potential promising outcome.Conclusion: PRP may improve the mesh-tissue integration.Keywords: mesh-augmented surgery, pelvic organ prolapse, platelet-rich plasma, wound healing.AbstrakTujuan: Untuk menganalisa keuntungan penggunaan PRP pada pembedahan rekonstruktif dengan mesh.Metode: Kajian pustaka dari penggunaan PRP pada pembedahan rekonstruktif dengan mesh.Hasil: Aplikasi PRP pada mesh menunjukkan hasil yang positif.Kesimpulan: Aplikasi PRP dapat meningkatkan integrasi mesh dengan jaringanKata kunci: pembedahan rekonstruksi dengan mesh, penyembuhan luka, platelet-rich plasma, prolaps organ panggul.
{"title":"Role of Platelet-Rich Plasma Application on Mesh-Tissue Integration","authors":"Alfa P. Meutia, B. Santoso, Suskhan Djusad","doi":"10.32771/inajog.v11i2.1721","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1721","url":null,"abstract":"AbstractObjective: To review the advantage of PRP use on mesh-augmented surgery.Methods: Literature review of PRP application of mesh.Results: The application of PRP on mesh shows potential promising outcome.Conclusion: PRP may improve the mesh-tissue integration.Keywords: mesh-augmented surgery, pelvic organ prolapse, platelet-rich plasma, wound healing.AbstrakTujuan: Untuk menganalisa keuntungan penggunaan PRP pada pembedahan rekonstruktif dengan mesh.Metode: Kajian pustaka dari penggunaan PRP pada pembedahan rekonstruktif dengan mesh.Hasil: Aplikasi PRP pada mesh menunjukkan hasil yang positif.Kesimpulan: Aplikasi PRP dapat meningkatkan integrasi mesh dengan jaringanKata kunci: pembedahan rekonstruksi dengan mesh, penyembuhan luka, platelet-rich plasma, prolaps organ panggul.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41401011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1888
Penggunaan Antibiotik, Operasi Sesar, Dokter Obstetri, dan Ginekologi, M. Akbar, R. Ulhaq, Indra Yuliati, M. Yusuf, B. Prasetyo, B. A. Tjokroprawiro
Objective: To evaluate the pattern of antibiotic use incesarean section `by obstetricians in Surabaya, Indonesia.Methods: This was a descriptive observational study witha cross-sectional method. Study data were obtained fromonline interviews using electronic forms. This study useda total sampling method taken from obstetricians andgynecologists in Surabaya, Indonesia. The primary outcomeof this study was a pattern of antibiotic use, includingprophylactic use, selection of antibiotics, the timing ofadministration, additional antibiotics during and aftersurgery, and consideration of choice.Results: The majority of antibiotics used in CS are in linewith the guidelines. The types of prophylactic antibiotics(iv) used are varied; the majority were cefazoline (74.5%),ceftriaxone (14.5%), and cefotaxime (11.6%). Most antibioticswere administered <30 minutes before surgery. 2.5% ofobstetricians routinely added antibiotics during a cesarean,while 33% were based on a particular condition such asprolonged surgery, massive bleeding, or risk of infections.The selection of antibiotics by obstetricians was based onprotocols followed in the hospital (44.5%).Conclusion: This study demonstrates that most obstetriciansutilized antibiotic prophylaxis appropriately and followedguidelines for Cesarean Section.Keywords: antibiotic, cesarean section, maternal health,obstetricians.AbstrakTujuan: Untuk mengevaluasi pola penggunaan antibiotikpada seksio sesarea oleh dokter kandungan di Surabaya,Indonesia.Metode: Ini merupakan studi deskriptif observasionaldengan metode pengambilan data potong lintang. Datastudi diperoleh dari wawancara online dengan menggunakanformulir elektronik. Studi ini menggunakan total samplingdari dokter obstetri dan ginekologi di Surabaya, Indonesia.Hasil utama dari penelitian ini adalah pola penggunaanantibiotik, termasuk penggunaan profi laksis, pemilihanantibiotik, waktu pemberian, antibiotik tambahan selamadan setelah operasi, dan pertimbangan pilihan antibiotiktersebut.Hasil: Mayoritas antibiotik yang digunakan pada seksiosesarea sesuai dengan pedoman. Jenis antibiotik profi laksis(iv) yang digunakan bervariasi, mayoritas adalah cefazoline(74,5%), ceftriaxone (14,5%), dan cefotaxime (11,6%).Sebagian besar antibiotik diberikan <30 menit sebelumoperasi. 2,5% dokter kandungan rutin menambahkanantibiotik saat operasi sesar, sedangkan 33% didasarkanpada kondisi tertentu seperti operasi yang berkepanjangan,perdarahan masif, atau risiko infeksi. Pemilihan antibiotikoleh dokter kandungan berdasarkan protokol yang diikutidi rumah sakit (44,5%).Kesimpulan: Studi ini menunjukkan bahwa sebagian besardokter kandungan menggunakan profi laksis antibiotikdengan tepat dan mengikuti pedoman untuk operasi seksiosesaria.Kata kunci: antibiotik, dokter kandungan, kesehatan ibu,operasi sesar.
目的:了解印度尼西亚泗水地区产科医生在剖宫产术中使用抗生素的情况。方法:采用横断面方法进行描述性观察性研究。研究数据采用电子表格从在线访谈中获得。本研究采用全抽样方法，从印度尼西亚泗水的妇产科医生中抽取。本研究的主要结果是抗生素使用的模式，包括预防性使用、抗生素的选择、给药时间、手术期间和术后额外的抗生素以及选择的考虑。结果:CS临床应用的抗生素大部分符合指南要求。使用的预防性抗生素种类多种多样;以头孢唑啉(74.5%)、头孢曲松(14.5%)、头孢噻肟(11.6%)为主。大多数抗生素是在手术前30分钟内使用的。2.5%的产科医生在剖宫产过程中常规添加抗生素，而33%的医生基于特定情况，如手术时间延长、大出血或感染风险。产科医生选择抗生素的依据是医院所遵循的方案(44.5%)。结论:本研究表明，大多数产科医生在剖宫产术中合理使用抗生素预防，并遵循指南。关键词:抗生素;剖宫产;孕产妇保健;【摘要】图juan: Untuk mengevaluasi pola penggunaan antibiotic sekpada sekarea,Indonesia, kandunungan di Surabaya。方法:利用气象学研究资料，对数据进行了分析和分析。数据分析，数据分析，数据分析，数据分析，数据分析。印度尼西亚泗水市产科与泌尿学研究。Hasil utama dari penelitian ini adalah pola penggunaanantibiotic tik, termasuk penggunaan profi laksis, pemilihanantibiotic tik, waktu pemberian, antibiotic tik tambahan selamadan setelah operasi, dan pertimbangan pilihan antibiotic tiktersebut。Hasil: Mayoritas antitik yang digunakan pada seksiosesarea sesuai dengan pedoman。Jenis抗生素profi - laksis(iv) yang digunakan bervariasi, mayoritas adalah头孢唑啉(74.5%)，头孢曲松(14.5%)，丹头孢噻肟(11.6%)。Sebagian besar抗生素diberikan <30分钟sebelumoperasi。2、5% dokter kandungan rutin menambahkan抗生素saat operassear, 33% didasarkanpada kondisi tertentu serperti operasyang berkepanjangan,perdarahan masif, atau visiko infeksi。pilihan antibiotic tikoleh dokter kandungan berdasarkan protokol yang diikutidi rumah sakit(44.5%)。研究结果表明:一种有效的抗生素治疗方法，一种有效的治疗方法，一种有效的治疗方法，一种有效的治疗方法。Kata kunci:抗生素，dokter kandungan, kesehatan ibu,operasi sesar。
{"title":"Antibiotic Use in Caesarean Section among Obstetricians and Gynaecologists in the Second Largest City in Indonesia","authors":"Penggunaan Antibiotik, Operasi Sesar, Dokter Obstetri, dan Ginekologi, M. Akbar, R. Ulhaq, Indra Yuliati, M. Yusuf, B. Prasetyo, B. A. Tjokroprawiro","doi":"10.32771/inajog.v11i2.1888","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1888","url":null,"abstract":"Objective: To evaluate the pattern of antibiotic use incesarean section `by obstetricians in Surabaya, Indonesia.Methods: This was a descriptive observational study witha cross-sectional method. Study data were obtained fromonline interviews using electronic forms. This study useda total sampling method taken from obstetricians andgynecologists in Surabaya, Indonesia. The primary outcomeof this study was a pattern of antibiotic use, includingprophylactic use, selection of antibiotics, the timing ofadministration, additional antibiotics during and aftersurgery, and consideration of choice.Results: The majority of antibiotics used in CS are in linewith the guidelines. The types of prophylactic antibiotics(iv) used are varied; the majority were cefazoline (74.5%),ceftriaxone (14.5%), and cefotaxime (11.6%). Most antibioticswere administered <30 minutes before surgery. 2.5% ofobstetricians routinely added antibiotics during a cesarean,while 33% were based on a particular condition such asprolonged surgery, massive bleeding, or risk of infections.The selection of antibiotics by obstetricians was based onprotocols followed in the hospital (44.5%).Conclusion: This study demonstrates that most obstetriciansutilized antibiotic prophylaxis appropriately and followedguidelines for Cesarean Section.Keywords: antibiotic, cesarean section, maternal health,obstetricians.AbstrakTujuan: Untuk mengevaluasi pola penggunaan antibiotikpada seksio sesarea oleh dokter kandungan di Surabaya,Indonesia.Metode: Ini merupakan studi deskriptif observasionaldengan metode pengambilan data potong lintang. Datastudi diperoleh dari wawancara online dengan menggunakanformulir elektronik. Studi ini menggunakan total samplingdari dokter obstetri dan ginekologi di Surabaya, Indonesia.Hasil utama dari penelitian ini adalah pola penggunaanantibiotik, termasuk penggunaan profi laksis, pemilihanantibiotik, waktu pemberian, antibiotik tambahan selamadan setelah operasi, dan pertimbangan pilihan antibiotiktersebut.Hasil: Mayoritas antibiotik yang digunakan pada seksiosesarea sesuai dengan pedoman. Jenis antibiotik profi laksis(iv) yang digunakan bervariasi, mayoritas adalah cefazoline(74,5%), ceftriaxone (14,5%), dan cefotaxime (11,6%).Sebagian besar antibiotik diberikan <30 menit sebelumoperasi. 2,5% dokter kandungan rutin menambahkanantibiotik saat operasi sesar, sedangkan 33% didasarkanpada kondisi tertentu seperti operasi yang berkepanjangan,perdarahan masif, atau risiko infeksi. Pemilihan antibiotikoleh dokter kandungan berdasarkan protokol yang diikutidi rumah sakit (44,5%).Kesimpulan: Studi ini menunjukkan bahwa sebagian besardokter kandungan menggunakan profi laksis antibiotikdengan tepat dan mengikuti pedoman untuk operasi seksiosesaria.Kata kunci: antibiotik, dokter kandungan, kesehatan ibu,operasi sesar.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43071802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.32771/inajog.v11i2.1872
Benedikta D. Saraswati, D. Suryandari, R. Kodariah, D. Sukmawati, L. Yunaini, P. Rustamadji, P. Sari, Sakit Dr. Cipto, Indonesia Mangunkusumo
and its correlation to i mRNA expression in low-grade and high-grade EOC’s patients from Dr. Cipto Mangunkusumo General hospital, Indonesia. Methods: This study is cross-sectional with a total of 65 healthy subjects and 80 ovarian biopsies (15 ovarian cysts as expression calibrators, 36 low-grade EOC, and 29 high-grade EOC) were used in this study. The distribution of genotypes and alleles was analyzed using ARMS PCR. The mRNA expressions of RELA were determined by real-time polymerase chain reaction (qPCR) analysis.Results: There was no significant difference between genotype and allele distributions for RELA rs11820062 in normal and case group. RELA relative mRNA expression was significantly higher in low-grade and high-grade EOC compared to in ovarian cysts (p<0.01). RELA rs11820062 CC genotype correlated to higher RELA mRNA relative expression and the TT genotype of RELA rs11820062 correlated with lower RELA mRNA relative expression in low-grade and high-grade EOC.Conclusion: C allele in rs11820062 caused an increased expression of RELA mRNA, which individuals with CC genotype correlated with higher RELA expression in low-grade and high-grade EOC. In contrast, individuals with the T allele of RELA rs11820062 had a protective effect against EOC risk because the RELA TT genotype tended to have a lower RELA mRNA expression in EOC.Keywords: epithelial ovarian cancer, NF-kB, RELA, rs11820062.AbstrakTujuan: Mengetahui distribusi RELA rs11820062 dan korelasinya dengan ekspresi mRNA RELA pada pasien EOC low-grade dan high-grade di Rumah Sakit Dr. Cipto Mangunkusumo, Indonesia.Metode: Penelitian ini merupakan peneliatan potong lintang terhadap 65 sampel darah perempuan normal dan total 80 biopsi kanker ovarium dengan rincian: 15 kista ovarium sebagai kalibrator ekspresi, 36 EOC low-grade, dan 29 EOC high-grade. Distribusi genotipe dan alel dianalisis menggunakan ARMS PCR dan ekspresi mRNA RELA dikuantifikasi menggunakan teknik qPCR. Hasil: Tidak terdapat perbedaan distribusi genotipe dan alel antara kelompok normal dengan kasus EOC. Ekspresi relatif mRNA RELA meningkat secara signifikan pada kelompok EOC low-grade dan high-grade. Individu dengan genotipe RELA rs11820062 homozigot CC memiliki ekspresi mRNA yang lebih tinggi dibandingkan genotipe lain. Sebaliknya individu dengan genotipe TT memiliki korelasi dengan ekspresi mRNA RELA yang lebih rendah pada tipe low-grade dan high-grade EOC. Kesimpulan: Alel C pada RELA rs11820062 menyebabkan peningkatan ekspresi mRNA RELA pada pasien EO yang dilihat dari individu dengan genotipe CC cenderung memiliki ekspresi mRNA RELA yang lebih tinggi pada tipe EOC low-grade dan high-grade. Sebaliknya, individu dengan alel T RELA rs11820062 diduga memiliki efek protektif terhadap risiko EOC karena adanya korelasi antara genotipe TT dengan ekspresi mRNA RELA yang lebih rendah pada EOC.Kata kunci: kanker ovarium epitelial, NF-kB, RELA, rs11820062.
{"title":"RELA mRNA Expression in Epithelial Ovarian Cancer: Correlation with rs11820062 Gene Variant","authors":"Benedikta D. Saraswati, D. Suryandari, R. Kodariah, D. Sukmawati, L. Yunaini, P. Rustamadji, P. Sari, Sakit Dr. Cipto, Indonesia Mangunkusumo","doi":"10.32771/inajog.v11i2.1872","DOIUrl":"https://doi.org/10.32771/inajog.v11i2.1872","url":null,"abstract":"and its correlation to i mRNA expression in low-grade and high-grade EOC’s patients from Dr. Cipto Mangunkusumo General hospital, Indonesia. Methods: This study is cross-sectional with a total of 65 healthy subjects and 80 ovarian biopsies (15 ovarian cysts as expression calibrators, 36 low-grade EOC, and 29 high-grade EOC) were used in this study. The distribution of genotypes and alleles was analyzed using ARMS PCR. The mRNA expressions of RELA were determined by real-time polymerase chain reaction (qPCR) analysis.Results: There was no significant difference between genotype and allele distributions for RELA rs11820062 in normal and case group. RELA relative mRNA expression was significantly higher in low-grade and high-grade EOC compared to in ovarian cysts (p<0.01). RELA rs11820062 CC genotype correlated to higher RELA mRNA relative expression and the TT genotype of RELA rs11820062 correlated with lower RELA mRNA relative expression in low-grade and high-grade EOC.Conclusion: C allele in rs11820062 caused an increased expression of RELA mRNA, which individuals with CC genotype correlated with higher RELA expression in low-grade and high-grade EOC. In contrast, individuals with the T allele of RELA rs11820062 had a protective effect against EOC risk because the RELA TT genotype tended to have a lower RELA mRNA expression in EOC.Keywords: epithelial ovarian cancer, NF-kB, RELA, rs11820062.AbstrakTujuan: Mengetahui distribusi RELA rs11820062 dan korelasinya dengan ekspresi mRNA RELA pada pasien EOC low-grade dan high-grade di Rumah Sakit Dr. Cipto Mangunkusumo, Indonesia.Metode: Penelitian ini merupakan peneliatan potong lintang terhadap 65 sampel darah perempuan normal dan total 80 biopsi kanker ovarium dengan rincian: 15 kista ovarium sebagai kalibrator ekspresi, 36 EOC low-grade, dan 29 EOC high-grade. Distribusi genotipe dan alel dianalisis menggunakan ARMS PCR dan ekspresi mRNA RELA dikuantifikasi menggunakan teknik qPCR. Hasil: Tidak terdapat perbedaan distribusi genotipe dan alel antara kelompok normal dengan kasus EOC. Ekspresi relatif mRNA RELA meningkat secara signifikan pada kelompok EOC low-grade dan high-grade. Individu dengan genotipe RELA rs11820062 homozigot CC memiliki ekspresi mRNA yang lebih tinggi dibandingkan genotipe lain. Sebaliknya individu dengan genotipe TT memiliki korelasi dengan ekspresi mRNA RELA yang lebih rendah pada tipe low-grade dan high-grade EOC. Kesimpulan: Alel C pada RELA rs11820062 menyebabkan peningkatan ekspresi mRNA RELA pada pasien EO yang dilihat dari individu dengan genotipe CC cenderung memiliki ekspresi mRNA RELA yang lebih tinggi pada tipe EOC low-grade dan high-grade. Sebaliknya, individu dengan alel T RELA rs11820062 diduga memiliki efek protektif terhadap risiko EOC karena adanya korelasi antara genotipe TT dengan ekspresi mRNA RELA yang lebih rendah pada EOC.Kata kunci: kanker ovarium epitelial, NF-kB, RELA, rs11820062.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45544926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-27DOI: 10.32771/inajog.v11i1.1676
Jane Belinda, Edihan Mardjuki, S. R. Bororing
Objective: To determine the sensitivity and specificity of the Mentzer and RDW index to assist in the diagnosis of iron deficiency anemia in first trimester pregnant women at RSIA Asih. Methods: This research was conducted by a cross-sectional method using the medical records of 100 samples of first trimester pregnant women with iron deficiency anemia by consecutive sampling and 100 samples of controls, which is also first trimester pregnant women with anemia. The data is then analyzed using Kolmogorov-Smirnov test and the independent-T test. Result: This study showed a significant relationship between the Mentzer index and the RDW index in iron deficiency anemia patients and control with p value = 0.000. Calculated by the ROC curve, the cut-off of Mentzer and RDW indices were 18.33 (sensitivity 37%, specificity 36%) and 249.2 (sensitivity 36%, spesificity 36%). Calculated by chi-square, the sensitivity and specificity values of the Mentzer index were 69% and 22% (literacy cut-off = 13), while the sensitivity and specificity values of the RDW index were 63% and 34% (literacy cut-off = 220). Conclusion: Mentzer index and RDW index cannot be proposed as the main parameter to help the establisment of iron deficiency anemia diagnosis in first trimester pregnant women.
{"title":"Mentzer and RDW Index in the Establishment of Iron Deficiency Anemia Diagnosis in the First Trimester of Pregnant Woman","authors":"Jane Belinda, Edihan Mardjuki, S. R. Bororing","doi":"10.32771/inajog.v11i1.1676","DOIUrl":"https://doi.org/10.32771/inajog.v11i1.1676","url":null,"abstract":"Objective: To determine the sensitivity and specificity of the Mentzer and RDW index to assist in the diagnosis of iron deficiency anemia in first trimester pregnant women at RSIA Asih. Methods: This research was conducted by a cross-sectional method using the medical records of 100 samples of first trimester pregnant women with iron deficiency anemia by consecutive sampling and 100 samples of controls, which is also first trimester pregnant women with anemia. The data is then analyzed using Kolmogorov-Smirnov test and the independent-T test. Result: This study showed a significant relationship between the Mentzer index and the RDW index in iron deficiency anemia patients and control with p value = 0.000. Calculated by the ROC curve, the cut-off of Mentzer and RDW indices were 18.33 (sensitivity 37%, specificity 36%) and 249.2 (sensitivity 36%, spesificity 36%). Calculated by chi-square, the sensitivity and specificity values of the Mentzer index were 69% and 22% (literacy cut-off = 13), while the sensitivity and specificity values of the RDW index were 63% and 34% (literacy cut-off = 220). Conclusion: Mentzer index and RDW index cannot be proposed as the main parameter to help the establisment of iron deficiency anemia diagnosis in first trimester pregnant women.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41893905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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