Pub Date : 2023-12-22DOI: 10.33371/ijoc.v17i4.1062
Nasdaldy Malik, M. Soemanadi, D. Mukarramah
Introduction: : Vulvar cancer is a rare disease accounting for approximately 5% of female genital tract tumors worldwide. It is a squamous cell cancer that mostly affects older women over the age of 65. In the existing body of literature, no instances of vulvar cancer have been documented in the form of case reports. Therefore, this study aimed to report the challenges and outcomes of vulvectomy with reconstructive flap in vulvar cancer survivors in a 39-year-old woman. Case Presentation: A 39-year-old woman with a palpable lump around the vulva was present and being examined. The anatomic pathology report (APR) features suggested poorly differentiated malignant tumors. A neoadjuvant chemotherapy was then administered to the patient aimed at shrinking the size of the tumor. However, there was no effective response to the chemotherapy, which resulted in a progressive tumor. Extensive vulvectomy and reconstructive flap were carried out to support quality of life, and the outcomes were reported, including flap, survival, complications, and mortality. These outcomes were evaluated between November 2021 and March 2023. No total flap loss was observed, and neither was there any donor site morbidity or mortality during the process. Conclusions: This study showed that vulvar cancer was a rare condition at a young age. Advanced vulvar cancer was found in the patients and extensive vulvectomy surgery was carried out followed by a pedicled ALT flap. This option was currently the best for immediate reconstruction due to the preservation of sensibility and tissue availability in the donor areas. The result showed no wound dehiscence, marginal necrosis, or surgical site infection. After 15 months of follow-up, the flap was observed to have good vascularization. The association of the Gynecologist with the Plastic Surgeon offered palliative care to improve the quality of life of the patient and provide good postoperative results.
{"title":"Extensive Vulvectomy and Reconstructive Flaps for Advanced Vulvar Cancer in Young Woman: Case Reports","authors":"Nasdaldy Malik, M. Soemanadi, D. Mukarramah","doi":"10.33371/ijoc.v17i4.1062","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.1062","url":null,"abstract":"Introduction: : Vulvar cancer is a rare disease accounting for approximately 5% of female genital tract tumors worldwide. It is a squamous cell cancer that mostly affects older women over the age of 65. In the existing body of literature, no instances of vulvar cancer have been documented in the form of case reports. Therefore, this study aimed to report the challenges and outcomes of vulvectomy with reconstructive flap in vulvar cancer survivors in a 39-year-old woman. Case Presentation: A 39-year-old woman with a palpable lump around the vulva was present and being examined. The anatomic pathology report (APR) features suggested poorly differentiated malignant tumors. A neoadjuvant chemotherapy was then administered to the patient aimed at shrinking the size of the tumor. However, there was no effective response to the chemotherapy, which resulted in a progressive tumor. Extensive vulvectomy and reconstructive flap were carried out to support quality of life, and the outcomes were reported, including flap, survival, complications, and mortality. These outcomes were evaluated between November 2021 and March 2023. No total flap loss was observed, and neither was there any donor site morbidity or mortality during the process. Conclusions: This study showed that vulvar cancer was a rare condition at a young age. Advanced vulvar cancer was found in the patients and extensive vulvectomy surgery was carried out followed by a pedicled ALT flap. This option was currently the best for immediate reconstruction due to the preservation of sensibility and tissue availability in the donor areas. The result showed no wound dehiscence, marginal necrosis, or surgical site infection. After 15 months of follow-up, the flap was observed to have good vascularization. The association of the Gynecologist with the Plastic Surgeon offered palliative care to improve the quality of life of the patient and provide good postoperative results. ","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"36 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138946729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-22DOI: 10.33371/ijoc.v17i4.1100
S. Darmiati, Rahmi Afifi, Christy Amanda Billy, S. S. Panigoro, D. Kartini, J. Prihartono
Background: Artificial intelligence (AI) is recognized to have tremendous potential to revolutionize breast cancer management through mammography. However, the extent of its impact on radiologists with different levels of experience remains largely unexplored. Therefore, this study aimed to comprehensively show how AI could assist radiologists of varying expertise including breast and non-breast radiologists, as well as senior residents, in performing mammogram interpretation.Methods: This retrospective study analyzed eligible mammograms from Cipto Mangunkusumo Hospital between January 2017 and March 2021. Mammographic readings were conducted independently by two breast radiologists, two from other subspecialties, and three senior residents, all blinded to clinical information. AI standalone performance, as well as radiologists with and without AI assistance, was measured. Results: The results showed that a total of 886 eligible mammograms were analyzed. AI standalone performance, assessed using ROC curve analysis, yielded an AUC of 0.946 (95% CI, 0.925–0.967) with sensitivity and specificity of 90.1% and 93.6%, respectively. AI assistance significantly improved the sensitivity and specificity of all radiologists, regardless of experience level, with a median increase of 19.4% (IQR, 10.4–33.5%) and 12.1% (IQR, 5.2–16.2%), respectively. Moreover, there was a trend toward a higher increase with AI assistance in dense compared to fatty breasts.Conclusions: AI proved to be a highly effective diagnostic supplement for radiologists across varying experience levels, specifically in non-breast radiologists, offering the potential to add even greater value in cases of dense breast tissue. The results were derived from a national referral tertiary hospital that generally received many breast cancer cases referred from other hospitals for further treatment. Therefore, further studies incorporating different levels of hospitals were needed.
{"title":"Impact of Artificial Intelligence on Mammography Interpretation by Breast Radiologists, Non-Breast Radiologists, and Senior Residents","authors":"S. Darmiati, Rahmi Afifi, Christy Amanda Billy, S. S. Panigoro, D. Kartini, J. Prihartono","doi":"10.33371/ijoc.v17i4.1100","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.1100","url":null,"abstract":"Background: Artificial intelligence (AI) is recognized to have tremendous potential to revolutionize breast cancer management through mammography. However, the extent of its impact on radiologists with different levels of experience remains largely unexplored. Therefore, this study aimed to comprehensively show how AI could assist radiologists of varying expertise including breast and non-breast radiologists, as well as senior residents, in performing mammogram interpretation.Methods: This retrospective study analyzed eligible mammograms from Cipto Mangunkusumo Hospital between January 2017 and March 2021. Mammographic readings were conducted independently by two breast radiologists, two from other subspecialties, and three senior residents, all blinded to clinical information. AI standalone performance, as well as radiologists with and without AI assistance, was measured. Results: The results showed that a total of 886 eligible mammograms were analyzed. AI standalone performance, assessed using ROC curve analysis, yielded an AUC of 0.946 (95% CI, 0.925–0.967) with sensitivity and specificity of 90.1% and 93.6%, respectively. AI assistance significantly improved the sensitivity and specificity of all radiologists, regardless of experience level, with a median increase of 19.4% (IQR, 10.4–33.5%) and 12.1% (IQR, 5.2–16.2%), respectively. Moreover, there was a trend toward a higher increase with AI assistance in dense compared to fatty breasts.Conclusions: AI proved to be a highly effective diagnostic supplement for radiologists across varying experience levels, specifically in non-breast radiologists, offering the potential to add even greater value in cases of dense breast tissue. The results were derived from a national referral tertiary hospital that generally received many breast cancer cases referred from other hospitals for further treatment. Therefore, further studies incorporating different levels of hospitals were needed.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"5 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138944818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Vaginal melanoma is a rare malignancy. Sadly, melanoma is a very aggressive tumor with a 5-year survival rate of 5%–25%. There is no publication about the incidence of vaginal malignant melanoma in Indonesia. Due to the lack of cases in Indonesia, this study aims to report the challenges and explore the risk factor, treatment, and prognosis of Vaginal Malignant Melanoma. Case Presentation: This case series report 2 patient with vaginal malignant melanoma who were diagnosed at Dharmais Cancer Center Hospital. Conclusions: Diagnosis and optimal treatment plans can be established through rapid and precise recognition of Malignant Melanoma to achieve better outcomes.
{"title":"A Case Series of Rare Vaginal Malignant Melanoma","authors":"Soemanadi Soemanadi, Widyorini Lestari Hutami Hanafi, Veinardi Madjid","doi":"10.33371/ijoc.v17i4.1104","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.1104","url":null,"abstract":"Introduction: Vaginal melanoma is a rare malignancy. Sadly, melanoma is a very aggressive tumor with a 5-year survival rate of 5%–25%. There is no publication about the incidence of vaginal malignant melanoma in Indonesia. Due to the lack of cases in Indonesia, this study aims to report the challenges and explore the risk factor, treatment, and prognosis of Vaginal Malignant Melanoma. Case Presentation: This case series report 2 patient with vaginal malignant melanoma who were diagnosed at Dharmais Cancer Center Hospital. Conclusions: Diagnosis and optimal treatment plans can be established through rapid and precise recognition of Malignant Melanoma to achieve better outcomes.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"38 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138946809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louis Fabio Jonathan Jusni, Richard Wijaya, Aileen Alessandra Suryohusodo
Background: Lung cancer is a significant health problem, ranking as the second most prevalent cancer worldwide and the leading cause of cancer-related mortality. Non-Small Cell Lung Cancer (NSCLC) accounts for a substantial portion of these cases. While histological biopsy is the golden standard for diagnosis of this disease, its invasiveness and associated risks show the need for an alternative approach. This review evaluates the potential of Isocitrate Dehydrogenase (IDH) as a specific serum biomarker for NSCLC detection. Aim: This study aimed to provide an overview of the diagnostic potential of IDH serum and identify gaps of knowledge for further investigations.Methods: A literature search was conducted across 3 databases, namely Pubmed, Science Direct, and Proquest, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.Results: The analysis of 4 studies showed a higher level of IDH in the serum of early-stage NSCLC patients before surgery compared to healthy control. Most investigations reported an AUC above 0.5 and were statistically significant.Conclusion: IDH has promising potential as a biomarker for diagnosing NSCLC. Future investigations should conduct a cohort study type to avoid bias and establish the definitive role of this enzyme as a reliable biomarker for NSCLC.
{"title":"The Role of Isocitrate Dehydrogenase as a Serum Biomarker in Detecting Non-Small Cell Lung Cancer: A Literature Review","authors":"Louis Fabio Jonathan Jusni, Richard Wijaya, Aileen Alessandra Suryohusodo","doi":"10.33371/ijoc.v17i4.997","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.997","url":null,"abstract":"Background: Lung cancer is a significant health problem, ranking as the second most prevalent cancer worldwide and the leading cause of cancer-related mortality. Non-Small Cell Lung Cancer (NSCLC) accounts for a substantial portion of these cases. While histological biopsy is the golden standard for diagnosis of this disease, its invasiveness and associated risks show the need for an alternative approach. This review evaluates the potential of Isocitrate Dehydrogenase (IDH) as a specific serum biomarker for NSCLC detection. Aim: This study aimed to provide an overview of the diagnostic potential of IDH serum and identify gaps of knowledge for further investigations.Methods: A literature search was conducted across 3 databases, namely Pubmed, Science Direct, and Proquest, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.Results: The analysis of 4 studies showed a higher level of IDH in the serum of early-stage NSCLC patients before surgery compared to healthy control. Most investigations reported an AUC above 0.5 and were statistically significant.Conclusion: IDH has promising potential as a biomarker for diagnosing NSCLC. Future investigations should conduct a cohort study type to avoid bias and establish the definitive role of this enzyme as a reliable biomarker for NSCLC.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"12 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138944509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amar Ma’ruf Irfan Muhamadi, Arief Sudarmaji, S. Pawiro
Background: The occurrence of motion in the thoracoabdominal region during radiotherapy treatment is an inherent challenge affecting the accuracy of the radiation beam. To address this challenge, a margin is often incorporated to compensate for the motion, but it has been reported to have several limitations. Consequently, respiratory gating has emerged as an integrated feature within radiotherapy-related machines. This innovative approach is designed to overcome motion-related challenges, leading to a reduction in the required margin and an improvement in the accuracy of the radiation beam. Methods: This study reviews the literature published in English between 2012 to 2021 regarding breathing monitoring devices used in the clinical or research stage. Furthermore, articles published before 2000 were traced to strengthen the theories. Results: Several monitoring devices had been reported to have respiratory gating purposes, but some were not equipped for this function. Furthermore, these devices were often developed using non-contact equipment, such as lasers and cameras, to provide accurate and precise measurements. One of their key advantages is the lack of physical attachment to the patients, thereby preserving comfort. The development of respiratory gating devices had significant potential to enhance the quality of radiotherapy treatment. This was manifested through more effective tumor and organ treatment and reduced toxicity. These benefits had the potential to extend the life expectancy of patients with respiratory-related cancer. Conclusions: Based on the results, respiratory gating was an advantageous technique in radiotherapy treatment. The development of respiratory gating devices enhanced patient comfort and the effectiveness of treatment.
{"title":"Recent Technological Advancements in Respiratory Gating Devices","authors":"Amar Ma’ruf Irfan Muhamadi, Arief Sudarmaji, S. Pawiro","doi":"10.33371/ijoc.v17i4.984","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.984","url":null,"abstract":"Background: The occurrence of motion in the thoracoabdominal region during radiotherapy treatment is an inherent challenge affecting the accuracy of the radiation beam. To address this challenge, a margin is often incorporated to compensate for the motion, but it has been reported to have several limitations. Consequently, respiratory gating has emerged as an integrated feature within radiotherapy-related machines. This innovative approach is designed to overcome motion-related challenges, leading to a reduction in the required margin and an improvement in the accuracy of the radiation beam. Methods: This study reviews the literature published in English between 2012 to 2021 regarding breathing monitoring devices used in the clinical or research stage. Furthermore, articles published before 2000 were traced to strengthen the theories. Results: Several monitoring devices had been reported to have respiratory gating purposes, but some were not equipped for this function. Furthermore, these devices were often developed using non-contact equipment, such as lasers and cameras, to provide accurate and precise measurements. One of their key advantages is the lack of physical attachment to the patients, thereby preserving comfort. The development of respiratory gating devices had significant potential to enhance the quality of radiotherapy treatment. This was manifested through more effective tumor and organ treatment and reduced toxicity. These benefits had the potential to extend the life expectancy of patients with respiratory-related cancer. Conclusions: Based on the results, respiratory gating was an advantageous technique in radiotherapy treatment. The development of respiratory gating devices enhanced patient comfort and the effectiveness of treatment.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"79 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138945479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-22DOI: 10.33371/ijoc.v17i4.1002
Indah Try Meylani, A. F. Benyamin, Tutik Harjianti, Mirna Muis, U. Miskad, Rahmawati Minhajat
Background: Breast cancer is a condition characterized by abnormal and uncontrollable growth of cells in breast tissue. According to Global Cancer Statistics 2020, it ranks as the leading cause of female cancer mortality. The disease has four subtypes defined by protein expression, namely Luminal A (ER/PR (+), HER2 (-)), Luminal B (ER/PR (+), HER2 (+)), triple-negative/basal-like (ER, PR, HER2 (-)), and HER2-enriched (ER (-), PR (-), HER2 (+)), each with distinct characteristics influenced by various risk factors. Therefore, this study aimed to explore the correlation between breast cancer risk factors and protein expression of ER, PR, and HER2. Methods: The cross-sectional analytical study was conducted in Makassar, Indonesia, using secondary data from 259 breast cancer patients. Information on ER, PR, HER2 expression, and patient risk factors such as age, history of hormonal contraceptive use, and family history of breast cancer were extracted from medical records and subjected to statistical analysis using the Chi-square test, with significance set at p < 0.05. Results: The results showed that there was a significant correlation between age ≥ 40 years and the expression of ER, PR, and HER2 (p < 0.005). However, no significant correlations were observed between family history and hormonal contraceptive use with ER, PR, and HER2 expression. Conclusions: This study established a meaningful correlation between risk factors of age and breast cancer subtypes based on ER, PR, and HER2 expression.
{"title":"Correlation between Risk Factors and Protein Expression of ER, PR, and HER-2 in Breast Cancer Patients: A Population-Based Study in Makassar Indonesia","authors":"Indah Try Meylani, A. F. Benyamin, Tutik Harjianti, Mirna Muis, U. Miskad, Rahmawati Minhajat","doi":"10.33371/ijoc.v17i4.1002","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.1002","url":null,"abstract":"Background: Breast cancer is a condition characterized by abnormal and uncontrollable growth of cells in breast tissue. According to Global Cancer Statistics 2020, it ranks as the leading cause of female cancer mortality. The disease has four subtypes defined by protein expression, namely Luminal A (ER/PR (+), HER2 (-)), Luminal B (ER/PR (+), HER2 (+)), triple-negative/basal-like (ER, PR, HER2 (-)), and HER2-enriched (ER (-), PR (-), HER2 (+)), each with distinct characteristics influenced by various risk factors. Therefore, this study aimed to explore the correlation between breast cancer risk factors and protein expression of ER, PR, and HER2. Methods: The cross-sectional analytical study was conducted in Makassar, Indonesia, using secondary data from 259 breast cancer patients. Information on ER, PR, HER2 expression, and patient risk factors such as age, history of hormonal contraceptive use, and family history of breast cancer were extracted from medical records and subjected to statistical analysis using the Chi-square test, with significance set at p < 0.05. Results: The results showed that there was a significant correlation between age ≥ 40 years and the expression of ER, PR, and HER2 (p < 0.005). However, no significant correlations were observed between family history and hormonal contraceptive use with ER, PR, and HER2 expression. Conclusions: This study established a meaningful correlation between risk factors of age and breast cancer subtypes based on ER, PR, and HER2 expression. ","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"34 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138946932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-22DOI: 10.33371/ijoc.v17i4.1075
Yan Wisnu Prajoko
Background: Dr. Kariadi General Hospital is the main provincial referral hospital in Central Java, serving a population of over 33 million. The oncology center of the hospital serves as the forefront service, which requires evaluation to ensure quality assessment and improvements. Therefore, this study aimed to provide valuable insights into chemotherapy nursing quality and level of patient satisfaction. Methods: This descriptive study assessed the quality of chemotherapy services given to breast cancer patients. The level of patient satisfaction was measured using the Worthing Chemotherapy Satisfaction Questionnaire (WCSQ). The questionnaire was used to evaluate patient satisfaction in six distinct components, which included patient education, the technical aspect of care, the interpersonal of the health worker, multidisciplinary teamwork, treatment environment, and hospital accessibility. The data obtained were collected by handing out questionnaires to eligible participants in the oncologic center. Results: The level of patient satisfaction was significantly affected by information received from medical personnel regardless of the sociodemographic characteristics. Other factors such as waiting time, treatment privacy, nursing skills, and efficiency of chemotherapy delivery also significantly improved patient satisfaction. Conclusions: The results showed that oncologists played a significant role in patient education. Furthermore, chemotherapy nurses were expected to deliver care and education, which positively correlated with patient satisfaction. Although the general level of satisfaction was acceptable, some areas still required further improvements to enhance the quality of service, specifically patient education.
{"title":"An Evaluation of The Quality of Breast Cancer Chemotherapy Service in Dr. Kariadi General Hospital","authors":"Yan Wisnu Prajoko","doi":"10.33371/ijoc.v17i4.1075","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.1075","url":null,"abstract":"Background: Dr. Kariadi General Hospital is the main provincial referral hospital in Central Java, serving a population of over 33 million. The oncology center of the hospital serves as the forefront service, which requires evaluation to ensure quality assessment and improvements. Therefore, this study aimed to provide valuable insights into chemotherapy nursing quality and level of patient satisfaction. Methods: This descriptive study assessed the quality of chemotherapy services given to breast cancer patients. The level of patient satisfaction was measured using the Worthing Chemotherapy Satisfaction Questionnaire (WCSQ). The questionnaire was used to evaluate patient satisfaction in six distinct components, which included patient education, the technical aspect of care, the interpersonal of the health worker, multidisciplinary teamwork, treatment environment, and hospital accessibility. The data obtained were collected by handing out questionnaires to eligible participants in the oncologic center. Results: The level of patient satisfaction was significantly affected by information received from medical personnel regardless of the sociodemographic characteristics. Other factors such as waiting time, treatment privacy, nursing skills, and efficiency of chemotherapy delivery also significantly improved patient satisfaction. Conclusions: The results showed that oncologists played a significant role in patient education. Furthermore, chemotherapy nurses were expected to deliver care and education, which positively correlated with patient satisfaction. Although the general level of satisfaction was acceptable, some areas still required further improvements to enhance the quality of service, specifically patient education.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"64 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139164208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-22DOI: 10.33371/ijoc.v17i4.1005
Michelle Trisya, Francisca Tjhay, S. Hasan, N. T. Widjaja
Background: The diagnosis and management of chronic diseases, such as Acute Lymphoblastic Leukemia (ALL), are significant for the quality of life of parents. In addition, several factors contribute to the quality of life of parents whose children battle ALL, including characteristics, duration of childcare, mental health, and family functioning. Therefore, this study aims to identify factors influencing the quality of life of parents whose children have ALL at the Childhood Cancer International Foundation in Jakarta. Methods: This cross-sectional study recruited 109 parents at the Childhood Cancer International Foundation as respondents. The assessment tools used included a Characteristics questionnaire, Self-Rating Questionnaire-20, APGAR Questionnaire, and WHOQOL-BREF questionnaire. Additionally, collected data were subjected to univariate, bivariate, and multivariate analysis. Results: Among the 109 respondents with an average age of 38 years and mean childcare duration of 28 months, 66.1% were females, 100% believed in God, 73.4% had partners, 47.7% possessed higher education, 83.5% earned below the regional minimum wage, 66.1% experienced mental health problems, and 11.9% had family dysfunction. Bivariate analysis showed a significant relationship between gender, mental health, and quality of life (p<0.05). Multivariate analysis showed that marital status, education, economic status, and family functioning significantly correlated with quality of life. Conclusions: In conclusion, gender, marital status, education, economic status, mental health, and family functioning were found to exert a significant influence on the quality of life of parents raising children with ALL.
背景：急性淋巴细胞白血病（ALL）等慢性疾病的诊断和管理对父母的生活质量意义重大。此外，子女患急性淋巴细胞白血病的父母的生活质量也受多种因素影响，包括特征、育儿时间、心理健康和家庭功能。因此，本研究旨在确定影响雅加达国际儿童癌症基金会（Childhood Cancer International Foundation）患儿父母生活质量的因素。研究方法这项横断面研究在国际儿童癌症基金会招募了 109 名家长作为受访者。使用的评估工具包括特征问卷、自评问卷-20、APGAR 问卷和 WHOQOL-BREF 问卷。此外，还对收集到的数据进行了单变量、双变量和多变量分析。结果在平均年龄为 38 岁、平均育儿时间为 28 个月的 109 名受访者中，66.1% 为女性，100% 信仰上帝，73.4% 有伴侣，47.7% 接受过高等教育，83.5% 的收入低于地区最低工资标准，66.1% 有心理健康问题，11.9% 有家庭功能障碍。双变量分析显示，性别、心理健康和生活质量之间存在显著关系（P<0.05）。多变量分析表明，婚姻状况、教育程度、经济状况和家庭功能与生活质量有明显的相关性。结论总之，性别、婚姻状况、教育程度、经济状况、心理健康和家庭功能对抚养 ALL 患儿的父母的生活质量有重要影响。
{"title":"Factors Influencing Quality of Life of Parents with Children Affected by Acute Lymphoblastic Leukemia: A Study at Childhood Cancer International Foundation, Jakarta","authors":"Michelle Trisya, Francisca Tjhay, S. Hasan, N. T. Widjaja","doi":"10.33371/ijoc.v17i4.1005","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.1005","url":null,"abstract":"Background: The diagnosis and management of chronic diseases, such as Acute Lymphoblastic Leukemia (ALL), are significant for the quality of life of parents. In addition, several factors contribute to the quality of life of parents whose children battle ALL, including characteristics, duration of childcare, mental health, and family functioning. Therefore, this study aims to identify factors influencing the quality of life of parents whose children have ALL at the Childhood Cancer International Foundation in Jakarta. Methods: This cross-sectional study recruited 109 parents at the Childhood Cancer International Foundation as respondents. The assessment tools used included a Characteristics questionnaire, Self-Rating Questionnaire-20, APGAR Questionnaire, and WHOQOL-BREF questionnaire. Additionally, collected data were subjected to univariate, bivariate, and multivariate analysis. Results: Among the 109 respondents with an average age of 38 years and mean childcare duration of 28 months, 66.1% were females, 100% believed in God, 73.4% had partners, 47.7% possessed higher education, 83.5% earned below the regional minimum wage, 66.1% experienced mental health problems, and 11.9% had family dysfunction. Bivariate analysis showed a significant relationship between gender, mental health, and quality of life (p<0.05). Multivariate analysis showed that marital status, education, economic status, and family functioning significantly correlated with quality of life. Conclusions: In conclusion, gender, marital status, education, economic status, mental health, and family functioning were found to exert a significant influence on the quality of life of parents raising children with ALL.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"18 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138947528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Colorectal adenocarcinoma is ranked third globally in the category of the most commonly diagnosed cancers, as reported by the Global Burden of Cancer (GLOBOCAN) survey in 2020. This condition ranks as the second leading cause of death from cancer with a mortality of 9.40%. Therefore, this study aimed to discover the clinicopathological profile of colorectal adenocarcinoma in the Anatomical Pathology Laboratory of Dr. Soedarso Hospital Pontianak in 2017–2020. Methods: This descriptive study used secondary data from the histopathology reports of the Anatomical Pathology Laboratory obtained by total sampling, which were processed using Microsoft Excel. Results: The total number of colorectal adenocarcinoma patients was 148, and the majority were in the category of 53–61 years, accounting for 30.41%, and 51.35% were female. The majority of the anatomical sites of tumors were in the “Rectum Not Otherwise Specified (NOS)”, with a percentage of 35.14%. The most frequent histopathological subtype was adenocarcinoma NOS, accounting for 85.81%, while the majority of differentiation grade was well differentiated, with a percentage of 90.54%. The most TNM (Tumor, Node, Metastatic) staging system of the American Joint Committee on Cancer (AJCC) was IIA (33.78%). Based on the classification using the Dukes staging system, the most stage suffered by patients was C2 with a percentage of 39.86%. Conclusions: In conclusion, the incidence of diagnosed colorectal adenocarcinoma cases increased yearly in the Anatomical Pathology Laboratory of Dr. Soedarso Hospital Pontianak. Further study of the clinical characteristics and analysis of risk factors in colorectal adenocarcinoma patients were important to support the development of effective preventive strategies.
{"title":"Clinicopathological Profile of Colorectal Adenocarcinoma in the Anatomical Pathology Laboratory of Dr. Soedarso Hospital Pontianak","authors":"Syarifah Shabrina Tsabit, Heru Fajar Trianto, Sari Eka Pratiwi, Henky Hartono","doi":"10.33371/ijoc.v17i4.1004","DOIUrl":"https://doi.org/10.33371/ijoc.v17i4.1004","url":null,"abstract":"Background: Colorectal adenocarcinoma is ranked third globally in the category of the most commonly diagnosed cancers, as reported by the Global Burden of Cancer (GLOBOCAN) survey in 2020. This condition ranks as the second leading cause of death from cancer with a mortality of 9.40%. Therefore, this study aimed to discover the clinicopathological profile of colorectal adenocarcinoma in the Anatomical Pathology Laboratory of Dr. Soedarso Hospital Pontianak in 2017–2020. Methods: This descriptive study used secondary data from the histopathology reports of the Anatomical Pathology Laboratory obtained by total sampling, which were processed using Microsoft Excel. Results: The total number of colorectal adenocarcinoma patients was 148, and the majority were in the category of 53–61 years, accounting for 30.41%, and 51.35% were female. The majority of the anatomical sites of tumors were in the “Rectum Not Otherwise Specified (NOS)”, with a percentage of 35.14%. The most frequent histopathological subtype was adenocarcinoma NOS, accounting for 85.81%, while the majority of differentiation grade was well differentiated, with a percentage of 90.54%. The most TNM (Tumor, Node, Metastatic) staging system of the American Joint Committee on Cancer (AJCC) was IIA (33.78%). Based on the classification using the Dukes staging system, the most stage suffered by patients was C2 with a percentage of 39.86%. Conclusions: In conclusion, the incidence of diagnosed colorectal adenocarcinoma cases increased yearly in the Anatomical Pathology Laboratory of Dr. Soedarso Hospital Pontianak. Further study of the clinical characteristics and analysis of risk factors in colorectal adenocarcinoma patients were important to support the development of effective preventive strategies.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"10 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138994197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Chemotherapy-induced acute nausea and vomiting are commonly experienced by breast cancer patients. Therefore, this study aimed to determine the effect of inhaled peppermint aromatherapy on chemotherapy-induced acute nausea and vomiting among women with breast cancer.Methods: This pre-experimental study was conducted using a one-group pre-post-test design approach. The sample included 28 women with breast cancer undergoing chemotherapy at the Chemotherapy Unit of Semen Gresik Hospital, Gresik, Indonesia. Respondents were administered 0.25 cc of peppermint essential oil on a cotton ball and then inhaled for 10 minutes. Data were collected using Rhodes Index Nausea Vomiting & Retching (RINVR) and analyzed with a paired sample t-test.Results: The pre-test showed that the majority of respondents experienced a moderate level of nausea and vomiting. After the intervention, the post-test results indicated mild nausea and vomiting. The statistical analysis showed that peppermint aromatherapy significantly affected chemotherapy-induced acute nausea and vomiting with a p-value of 0.001 (α<0.05).Conclusions: There was a significant improvement in chemotherapy-induced acute nausea and vomiting after the administration of peppermint aromatherapy. Therefore, this intervention could be used as a non-pharmacological complementary therapy to reduce chemotherapyrelated nausea among breast cancer patients
{"title":"Effect of Inhaled Peppermint Aromatherapy on Chemotherapy-Induced Acute Nausea and Vomiting among Women with Breast Cancer in Gresik Regency","authors":"Istiroha Istiroha, Roihatul Zahroh, Qonitatin Wafiyah, Yuanita Syaiful","doi":"10.33371/ijoc.v17i3.987","DOIUrl":"https://doi.org/10.33371/ijoc.v17i3.987","url":null,"abstract":"Background: Chemotherapy-induced acute nausea and vomiting are commonly experienced by breast cancer patients. Therefore, this study aimed to determine the effect of inhaled peppermint aromatherapy on chemotherapy-induced acute nausea and vomiting among women with breast cancer.Methods: This pre-experimental study was conducted using a one-group pre-post-test design approach. The sample included 28 women with breast cancer undergoing chemotherapy at the Chemotherapy Unit of Semen Gresik Hospital, Gresik, Indonesia. Respondents were administered 0.25 cc of peppermint essential oil on a cotton ball and then inhaled for 10 minutes. Data were collected using Rhodes Index Nausea Vomiting & Retching (RINVR) and analyzed with a paired sample t-test.Results: The pre-test showed that the majority of respondents experienced a moderate level of nausea and vomiting. After the intervention, the post-test results indicated mild nausea and vomiting. The statistical analysis showed that peppermint aromatherapy significantly affected chemotherapy-induced acute nausea and vomiting with a p-value of 0.001 (α<0.05).Conclusions: There was a significant improvement in chemotherapy-induced acute nausea and vomiting after the administration of peppermint aromatherapy. Therefore, this intervention could be used as a non-pharmacological complementary therapy to reduce chemotherapyrelated nausea among breast cancer patients","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135247666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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