Background: Cancer therapy during the pandemic causes physical and psychological problems. It impacts happiness in their lives. Laughter yoga is an intervention that can increase happiness. The purpose of this study is to prove that laughter yoga can increase the achievement of individual and peer happiness in cancer patients undergoing therapy in a pandemic situation. Methods: This was a quasi-experimental with a non-equivalent control group design. The total sample was 40 cancer patients at the Indonesia Cancer Foundation East Java selected through the inclusion and exclusion criteria. In the implementation, 20 people belong to the intervention group (IG) and 20 other people belong to the control group (CG). The IG provided laughter yoga 2x/a week for 4 weeks with 14 steps, while CG only through daily activities. Both groups conducted pre-test and post-tests using The Subjective Happiness Scale. The scale consists of two indicators: individual happiness and peers’ happiness. In addition, the calculation of the two indicators is done separately. The instrument has been tested for its validity and reliability. The data were normally distributed (Shapiro-Wilk test p > 0.05). Statistical test was conducted using paired t-test (p < 0.05) to test the pre-post data in both groups and independent sample t-test (p < 0.05) to test the effectiveness of the intervention compared to the control group.Results: Demographic data of respondents was homogenous. The mean score of individual and peer happiness before and after intervention in the IG increased. It means that respondents had better happiness. Meanwhile, in the CG there was a stagnation score of individual and peer happiness. Paired t-test in the IG showed that individual and peers’ happiness got the same p-value < 0.001 each. In the CG, individual happiness records p = 1.000 and peers’ happiness p = 0.083. Statistical tests conducted by Independent t-test to compare IG and CG had the p = 0.012 for individual happiness and p = < 0.001 for peers’ happiness.Conclusions: Laughter yoga has a significant effect to enhance individual and peer happiness compared to respondents who only carry out normal daily activities, especially for cancer patients undergoing therapy during the COVID-19 pandemic.
{"title":"The Effectiveness of Laughter Yoga to Improve Individual and Peer Happiness Among Cancer Patients","authors":"Yesiana Dwi Wahyu Werdani","doi":"10.33371/ijoc.v17i1.940","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.940","url":null,"abstract":"Background: Cancer therapy during the pandemic causes physical and psychological problems. It impacts happiness in their lives. Laughter yoga is an intervention that can increase happiness. The purpose of this study is to prove that laughter yoga can increase the achievement of individual and peer happiness in cancer patients undergoing therapy in a pandemic situation. Methods: This was a quasi-experimental with a non-equivalent control group design. The total sample was 40 cancer patients at the Indonesia Cancer Foundation East Java selected through the inclusion and exclusion criteria. In the implementation, 20 people belong to the intervention group (IG) and 20 other people belong to the control group (CG). The IG provided laughter yoga 2x/a week for 4 weeks with 14 steps, while CG only through daily activities. Both groups conducted pre-test and post-tests using The Subjective Happiness Scale. The scale consists of two indicators: individual happiness and peers’ happiness. In addition, the calculation of the two indicators is done separately. The instrument has been tested for its validity and reliability. The data were normally distributed (Shapiro-Wilk test p > 0.05). Statistical test was conducted using paired t-test (p < 0.05) to test the pre-post data in both groups and independent sample t-test (p < 0.05) to test the effectiveness of the intervention compared to the control group.Results: Demographic data of respondents was homogenous. The mean score of individual and peer happiness before and after intervention in the IG increased. It means that respondents had better happiness. Meanwhile, in the CG there was a stagnation score of individual and peer happiness. Paired t-test in the IG showed that individual and peers’ happiness got the same p-value < 0.001 each. In the CG, individual happiness records p = 1.000 and peers’ happiness p = 0.083. Statistical tests conducted by Independent t-test to compare IG and CG had the p = 0.012 for individual happiness and p = < 0.001 for peers’ happiness.Conclusions: Laughter yoga has a significant effect to enhance individual and peer happiness compared to respondents who only carry out normal daily activities, especially for cancer patients undergoing therapy during the COVID-19 pandemic.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"436 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83634466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raden Nabilah Putri Fauziyyah, Maria Komariah, Yusshy Kurnia Herliani
Background: Skin cancer ranks fifth in the world. Melanoma, a type of skin cancer, ranks 23rd in Indonesia. Meanwhile, deaths caused by skin cancer are more than half of the number of new cases in Indonesia. Indonesia is a country that lies across the equator. It makes Indonesia have longer exposure to sunlight and a higher UV index. This study aims to describe the sunlight exposure level and protection behavior among nursing students.Methods: The samples of this study were 248 respondents from the Faculty of Nursing, Universitas Padjadjaran, who were recruited with a convenience sampling technique. Data were collected using a modified Sun Exposure Behaviour Inventory (SEBI). The data were processed using SPSS statistical software to determine behavioral descriptions and exposure to sunlight. Then, the result of the data analysis was performed with descriptive analysis (frequency and percentage).Results: The result of this study showed that most of the respondents (84.3%) always used longsleeved clothes to cover their shoulders. Most respondents (85.9%) used sunscreen with a Sun Protection Factor (SPF) of 15 or more, and more than half of the respondents (68.5%) used sunscreen that can protect from Ultraviolet A (UVA) and Ultraviolet B (UVB). Most respondents (76.2%) never spent time under natural or artificial Ultraviolet Radiation (UVR) to get the desired brown skin. More than half of the respondents (66.9%) had never sunbathed in the last 12 months. Conclusions: More than half of the respondents had adequate protective behavior against sun exposure and had moderate sun exposure. Using sunscreens with a higher SPF has shown a stronger preventive effect. Therefore, regular use of sunscreen can decrease the risk of skin cancer.
{"title":"Sunlight Exposure and Protection Behavior as Prevention of Skin Cancer in Nursing Students","authors":"Raden Nabilah Putri Fauziyyah, Maria Komariah, Yusshy Kurnia Herliani","doi":"10.33371/ijoc.v17i1.921","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.921","url":null,"abstract":"Background: Skin cancer ranks fifth in the world. Melanoma, a type of skin cancer, ranks 23rd in Indonesia. Meanwhile, deaths caused by skin cancer are more than half of the number of new cases in Indonesia. Indonesia is a country that lies across the equator. It makes Indonesia have longer exposure to sunlight and a higher UV index. This study aims to describe the sunlight exposure level and protection behavior among nursing students.Methods: The samples of this study were 248 respondents from the Faculty of Nursing, Universitas Padjadjaran, who were recruited with a convenience sampling technique. Data were collected using a modified Sun Exposure Behaviour Inventory (SEBI). The data were processed using SPSS statistical software to determine behavioral descriptions and exposure to sunlight. Then, the result of the data analysis was performed with descriptive analysis (frequency and percentage).Results: The result of this study showed that most of the respondents (84.3%) always used longsleeved clothes to cover their shoulders. Most respondents (85.9%) used sunscreen with a Sun Protection Factor (SPF) of 15 or more, and more than half of the respondents (68.5%) used sunscreen that can protect from Ultraviolet A (UVA) and Ultraviolet B (UVB). Most respondents (76.2%) never spent time under natural or artificial Ultraviolet Radiation (UVR) to get the desired brown skin. More than half of the respondents (66.9%) had never sunbathed in the last 12 months. Conclusions: More than half of the respondents had adequate protective behavior against sun exposure and had moderate sun exposure. Using sunscreens with a higher SPF has shown a stronger preventive effect. Therefore, regular use of sunscreen can decrease the risk of skin cancer.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"315 9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77176998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Sexual problems are associated with almost all types of cancers, especially those of the genital regions. Sexual problems can occur due to cancer itself or due to its treatment (chemotherapy, radiotherapy, or surgery) across all the stages of cancer and its management.Methods: The researcher reviewed the current research status of this less-discussed issue. 115 articles were identified using predefined keywords in Pubmed, Pubmed Central, Embase, and Google Scholar databases from January 1, 2000, to March 31, 2022. First, the articles were screened based on the abstracts followed by checking for the availability of their full-text versions. A total of 28 articles fulfilling the inclusion criteria were finally selected and analyzed. Results: Common sexual problems found in men were erectile dysfunction, decreased libido, dry ejaculation, and performance anxiety. On the other hand, women usually complained of reduced intimacy, lack of sexual desire, vaginal dryness, pain during intercourse, lack of sexual sensation, and reduced self-esteem for sexual activities. There is a significant prevalence of sexual problems with effects on marital relationships in cancer patients. Psychiatric disorders were found to be associated with a higher prevalence of sexual dysfunction ranging from 70 to 90% compared to the general population. Up to 50% and 40% of female and male patients with depression (a common occurrence in cancer) respectively may have sexual dysfunctions. Conclusions: Management of these problems is necessary, as it can be a contributing factor to the poor quality of life. Communication and discussion about sexual health from patients as well as the healthcare provider side are needed. The urgency of seeking a specialist’s help such as a psychiatrist or a sex therapist is also discussed. The researcher reviewed common sexual problems, causes, and treatment modalities, and suggested a few recommendations for making sexual health a part of routine cancer check-ups.
{"title":"Sexual Rehabilitation of Cancer Patients: A Less Noticed Domain in Cancer Care","authors":"A. Faye","doi":"10.33371/ijoc.v17i1.929","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.929","url":null,"abstract":"Background: Sexual problems are associated with almost all types of cancers, especially those of the genital regions. Sexual problems can occur due to cancer itself or due to its treatment (chemotherapy, radiotherapy, or surgery) across all the stages of cancer and its management.Methods: The researcher reviewed the current research status of this less-discussed issue. 115 articles were identified using predefined keywords in Pubmed, Pubmed Central, Embase, and Google Scholar databases from January 1, 2000, to March 31, 2022. First, the articles were screened based on the abstracts followed by checking for the availability of their full-text versions. A total of 28 articles fulfilling the inclusion criteria were finally selected and analyzed. Results: Common sexual problems found in men were erectile dysfunction, decreased libido, dry ejaculation, and performance anxiety. On the other hand, women usually complained of reduced intimacy, lack of sexual desire, vaginal dryness, pain during intercourse, lack of sexual sensation, and reduced self-esteem for sexual activities. There is a significant prevalence of sexual problems with effects on marital relationships in cancer patients. Psychiatric disorders were found to be associated with a higher prevalence of sexual dysfunction ranging from 70 to 90% compared to the general population. Up to 50% and 40% of female and male patients with depression (a common occurrence in cancer) respectively may have sexual dysfunctions. Conclusions: Management of these problems is necessary, as it can be a contributing factor to the poor quality of life. Communication and discussion about sexual health from patients as well as the healthcare provider side are needed. The urgency of seeking a specialist’s help such as a psychiatrist or a sex therapist is also discussed. The researcher reviewed common sexual problems, causes, and treatment modalities, and suggested a few recommendations for making sexual health a part of routine cancer check-ups.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75327724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aditya Eka Octavian, M. Yamsun, Gita Nawangtantrini
Introduction: Krukenberg Tumor is an ovarian tumor that originated from other organ metastases such as gastric, colorectal, pylorus, appendix, colorectal, or breasts. This study aims to report an incidence of a Krukenberg tumor found in a-36year- old woman who has finished her therapy at Margono Soekarjo Hospital.Case Presentation: This case reports the incidence of a Krukenberg tumor found in a-36-year old woman with the main complaint of a burning sensation in her stomach and the existence of a mass in the right and under the Arcus Costae. The patient underwent metastasectomy and biopsy. Histopathological examinations show that the features of Krukenberg tumor originated from a gaster. The patient then underwent chemotherapy for 6 cycles, radiotherapy 20 times, and some evaluation. This case had been observed for 12 months since the first time the patient came to the hospital.Conclusions: Krukenberg tumor is a rare tumor of the ovary which is characterized by poor prognosis. This case depicts the finding of Krukenberg tumor with gastric clinical features. The combination of metastasectomy and chemotherapy can be done in such a case to improve patient survival rates.
{"title":"A Rare Clinical Entity of Krukenberg Tumor: A Case Report in Margono Soekarjo Hospital of Purwokerto","authors":"Aditya Eka Octavian, M. Yamsun, Gita Nawangtantrini","doi":"10.33371/ijoc.v17i1.931","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.931","url":null,"abstract":"Introduction: Krukenberg Tumor is an ovarian tumor that originated from other organ metastases such as gastric, colorectal, pylorus, appendix, colorectal, or breasts. This study aims to report an incidence of a Krukenberg tumor found in a-36year- old woman who has finished her therapy at Margono Soekarjo Hospital.Case Presentation: This case reports the incidence of a Krukenberg tumor found in a-36-year old woman with the main complaint of a burning sensation in her stomach and the existence of a mass in the right and under the Arcus Costae. The patient underwent metastasectomy and biopsy. Histopathological examinations show that the features of Krukenberg tumor originated from a gaster. The patient then underwent chemotherapy for 6 cycles, radiotherapy 20 times, and some evaluation. This case had been observed for 12 months since the first time the patient came to the hospital.Conclusions: Krukenberg tumor is a rare tumor of the ovary which is characterized by poor prognosis. This case depicts the finding of Krukenberg tumor with gastric clinical features. The combination of metastasectomy and chemotherapy can be done in such a case to improve patient survival rates.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89784039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ririn Afrian Sulistyawati, Santoso Santoso, L. Azali, Galih Setia Adi
Background: Cancer patients are 3.5 times more susceptible to COVID-19 than patients without cancer. The increasing number of COVID-19 patients is likely to impact cancer patients’ quality of life (QoL) significantly. This study aims to analyze the QoL of cancer patients during the COVID-19 pandemic. Methods: The method used is quantitative with a cross-sectional research design. In this study, 60 respondents were selected using the Consecutive Sampling Technique. The patient’s QoL was measured once by utilizing The World Health Organization Quality of Life Brief Version (WHOQOL BREF) instrument. The QoL of cancer patients was shown in mean and standard deviation, and the correlation between respondent characteristics and QoL was analyzed with Spearman.Results: The results showed that the average QoL of the respondents in the physical health was 30.36 ± 7.72, the intermediate psychological was 25.88 ± 9.14, the average social relationship was 59.90 ± 13.04, and the mean environment was 56.7 ± 10.93.Conclusions: Respondents’ low QoL during the COVID-19 pandemic for all domains. This study implies the importance of paying attention to every domain of the QoL of cancer patients, especially during the COVID-19 pandemic.
{"title":"A Preliminary Study on Cancer Patients’ Quality of Life during the COVID-19 Pandemic","authors":"Ririn Afrian Sulistyawati, Santoso Santoso, L. Azali, Galih Setia Adi","doi":"10.33371/ijoc.v17i1.938","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.938","url":null,"abstract":"Background: Cancer patients are 3.5 times more susceptible to COVID-19 than patients without cancer. The increasing number of COVID-19 patients is likely to impact cancer patients’ quality of life (QoL) significantly. This study aims to analyze the QoL of cancer patients during the COVID-19 pandemic. Methods: The method used is quantitative with a cross-sectional research design. In this study, 60 respondents were selected using the Consecutive Sampling Technique. The patient’s QoL was measured once by utilizing The World Health Organization Quality of Life Brief Version (WHOQOL BREF) instrument. The QoL of cancer patients was shown in mean and standard deviation, and the correlation between respondent characteristics and QoL was analyzed with Spearman.Results: The results showed that the average QoL of the respondents in the physical health was 30.36 ± 7.72, the intermediate psychological was 25.88 ± 9.14, the average social relationship was 59.90 ± 13.04, and the mean environment was 56.7 ± 10.93.Conclusions: Respondents’ low QoL during the COVID-19 pandemic for all domains. This study implies the importance of paying attention to every domain of the QoL of cancer patients, especially during the COVID-19 pandemic.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91314008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-28DOI: 10.33371/ijoc.v17i1.1021
D. Cahyanti, S. Syarif, Septiawati -, E. Suzanna
Background: Almost 95% of laryngeal cancers are squamous cell carcinoma. Most of them come from the supraglottic and glottic regions. Globally from 1990 to 2017, there was an increase in the incidence of laryngeal cancer by 58.67%. Patients with suggestive grievances of laryngeal cancer symptoms are usually advised to do a further examination. The use of multimodality diagnosis is helpful for the diagnosis of cancer. Diagnostic procedures in diagnosing laryngeal cancer can be made by history and physical examination, clinical (laryngoscopy), and supporting examination (radiology and biopsy). This study aims to determine the distribution of the demographic (gender, age, domicile, marital status, and educational level), clinical distribution (voice changes, respiratory disorders, pain, dizziness, cough, lump on the neck, and others), and modalities of diagnosis (anamnesis, clinical examination, radiology, and biopsy) in laryngeal cancer.Methods: Descriptive study and a routine data-based study was conducted by collecting data on cancer patients who were diagnosed with laryngeal cancer from 2003 to 2007 by the microscopic either in Dharmais National Cancer Hospital (DNCH) or other hospitals. The study sample was 53 out of a total of 68 cases of laryngeal cancer who had been diagnosed with malignancy histopathologically at DNCH or in other hospitals with epithelial or non-epithelial types with completed medical records. Results: The glottic region is the most common subsite, that is, 52.8%, and squamous cell carcinoma (SCC) is the most common histopathological type of laryngeal cancer. In most of the cases, either males or females presented with a change in the voice of 68.8% and 80% respectively. In 6 out of 12 cases have not been examined microscopically before, while 7.5%.of the cases have done the diagnostic procedure completely in DNCH. Conclusions: The most common subsite and histopathological type of laryngeal cancer is glottis and SCC. The most common clinical feature in both sexes is voice changes. Most cases have not been examined according to the standard diagnosis procedure completely.
{"title":"Multimodality Diagnosis of Laryngeal Cancer in “Dharmais” National Cancer Hospital (DNCH)","authors":"D. Cahyanti, S. Syarif, Septiawati -, E. Suzanna","doi":"10.33371/ijoc.v17i1.1021","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.1021","url":null,"abstract":"Background: Almost 95% of laryngeal cancers are squamous cell carcinoma. Most of them come from the supraglottic and glottic regions. Globally from 1990 to 2017, there was an increase in the incidence of laryngeal cancer by 58.67%. Patients with suggestive grievances of laryngeal cancer symptoms are usually advised to do a further examination. The use of multimodality diagnosis is helpful for the diagnosis of cancer. Diagnostic procedures in diagnosing laryngeal cancer can be made by history and physical examination, clinical (laryngoscopy), and supporting examination (radiology and biopsy). This study aims to determine the distribution of the demographic (gender, age, domicile, marital status, and educational level), clinical distribution (voice changes, respiratory disorders, pain, dizziness, cough, lump on the neck, and others), and modalities of diagnosis (anamnesis, clinical examination, radiology, and biopsy) in laryngeal cancer.Methods: Descriptive study and a routine data-based study was conducted by collecting data on cancer patients who were diagnosed with laryngeal cancer from 2003 to 2007 by the microscopic either in Dharmais National Cancer Hospital (DNCH) or other hospitals. The study sample was 53 out of a total of 68 cases of laryngeal cancer who had been diagnosed with malignancy histopathologically at DNCH or in other hospitals with epithelial or non-epithelial types with completed medical records. Results: The glottic region is the most common subsite, that is, 52.8%, and squamous cell carcinoma (SCC) is the most common histopathological type of laryngeal cancer. In most of the cases, either males or females presented with a change in the voice of 68.8% and 80% respectively. In 6 out of 12 cases have not been examined microscopically before, while 7.5%.of the cases have done the diagnostic procedure completely in DNCH. Conclusions: The most common subsite and histopathological type of laryngeal cancer is glottis and SCC. The most common clinical feature in both sexes is voice changes. Most cases have not been examined according to the standard diagnosis procedure completely.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85101928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Primary cutaneous diffuse large B-cell lymphoma (PCDLBCL) is a variety of B-cell neoplasms that are present in the skin with no evidence of extra-cutaneous disease at the time of diagnosis or even after 6 months of the diagnosis. Cutaneous B-cell Lymphoma (CBCL) comprises 25 to 35% of all primary cutaneous lymphomas. Due to the relative rarity of PCDLBCL, there are no completed randomized trials to clarify the optimal treatment. Reported therapy options include radiotherapy, multiagent chemotherapy, chemotherapy, polychemotherapy with rituximab, and rituximab as a single agent.Case Presentation: Several red nodular lesions on the back developed over 10 months are found in a 40-year-old woman. The first Incision biopsy revealed these lesions were malignant roundcell tumors. After being treated with 10 cycles of chemotherapy regimens comprising cyclophosphamide, doxorubicin, vincristine, dan prednisone (CHOP), there was a progressive response as several red nodular lesions are getting larger and turned into an ulcerated wound. Wide excisions and skin flaps were done. Anatomical pathology examination showed diffuse non-Hodgkin lymphoma, a large B cell that belongs to intermediate malignancy, as immunohistochemistry was positive for CD20 and CD45. The patient was then diagnosed with primary cutaneous diffuse large B-cell lymphoma and given rituximab, a CD20-targeted therapy. The patient was allowed to be discharged on the second day after surgery.Conclusions: This case report presents cases of CHOP chemotherapy-unresponsive PCDLBCL in Abdul Wahab Sjahranie Regional Public Hospital of Samarinda, East Kalimantan.
{"title":"Cases of CHOP Chemotherapy - Unresponsive Primary Cutaneous Diffuse of Large B-Cell Lymphoma in Abdul Wahab Sjahranie Regional Public Hospital: A Case Presentation and Brief Review of Literature","authors":"Viky Hibatu Wafi, Z. Abidin","doi":"10.33371/ijoc.v17i1.953","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.953","url":null,"abstract":"Introduction: Primary cutaneous diffuse large B-cell lymphoma (PCDLBCL) is a variety of B-cell neoplasms that are present in the skin with no evidence of extra-cutaneous disease at the time of diagnosis or even after 6 months of the diagnosis. Cutaneous B-cell Lymphoma (CBCL) comprises 25 to 35% of all primary cutaneous lymphomas. Due to the relative rarity of PCDLBCL, there are no completed randomized trials to clarify the optimal treatment. Reported therapy options include radiotherapy, multiagent chemotherapy, chemotherapy, polychemotherapy with rituximab, and rituximab as a single agent.Case Presentation: Several red nodular lesions on the back developed over 10 months are found in a 40-year-old woman. The first Incision biopsy revealed these lesions were malignant roundcell tumors. After being treated with 10 cycles of chemotherapy regimens comprising cyclophosphamide, doxorubicin, vincristine, dan prednisone (CHOP), there was a progressive response as several red nodular lesions are getting larger and turned into an ulcerated wound. Wide excisions and skin flaps were done. Anatomical pathology examination showed diffuse non-Hodgkin lymphoma, a large B cell that belongs to intermediate malignancy, as immunohistochemistry was positive for CD20 and CD45. The patient was then diagnosed with primary cutaneous diffuse large B-cell lymphoma and given rituximab, a CD20-targeted therapy. The patient was allowed to be discharged on the second day after surgery.Conclusions: This case report presents cases of CHOP chemotherapy-unresponsive PCDLBCL in Abdul Wahab Sjahranie Regional Public Hospital of Samarinda, East Kalimantan.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81451925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Breast cancer cases are more commonly diagnosed in postmenopausal women and the risk increases with age. Along with an increased vulnerability to breast cancer, increasing age also carries a higher risk of other health problems. Postmenopausal breast cancer patients frequently have one or more pre-existing comorbid conditions at the time of diagnosis. Higher physical activity can reduce breast cancer-specific and overall mortality. However, the vast majority of early breast cancer survivors experience a decrease in physical activity. This study aimed to determine the relationship between physical activity and the reduction of Breast Cancer-Specific Mortality (BCSM) and overall mortality in postmenopausal breast cancer survivors.Methods: This research uses a literature review design by conducting a journal search through Google Scholar, PubMed, and ScienceDirect. The keywords used are (“Physical activity” or Exercise) and (“Breast Cancer” or “Breast Neoplasm”) and (Mortality) and (“Post-menopause”).Results: Seven studies were included in this review. A total of 6276 deaths were reported. Only 3 out of 6 studies reported that there is a significant benefit between physical activity and reduction in breast cancer-specific mortality. Contrarily, all studies reported that there is a significant benefit between physical activity and overall mortality reduction, but at a certain intensity level. Conclusions: Our data suggest that physical activity, whether pre-diagnosis or post-diagnosis, is associated with a better prognosis of breast cancer in postmenopausal women.
{"title":"The Benefits of Physical Activity to Reduce Mortality in Postmenopausal Breast Cancer Patients: A Literature Review","authors":"Thomas Jaya Gumilang, Budi J. Hernawan","doi":"10.33371/ijoc.v17i1.917","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.917","url":null,"abstract":"Background: Breast cancer cases are more commonly diagnosed in postmenopausal women and the risk increases with age. Along with an increased vulnerability to breast cancer, increasing age also carries a higher risk of other health problems. Postmenopausal breast cancer patients frequently have one or more pre-existing comorbid conditions at the time of diagnosis. Higher physical activity can reduce breast cancer-specific and overall mortality. However, the vast majority of early breast cancer survivors experience a decrease in physical activity. This study aimed to determine the relationship between physical activity and the reduction of Breast Cancer-Specific Mortality (BCSM) and overall mortality in postmenopausal breast cancer survivors.Methods: This research uses a literature review design by conducting a journal search through Google Scholar, PubMed, and ScienceDirect. The keywords used are (“Physical activity” or Exercise) and (“Breast Cancer” or “Breast Neoplasm”) and (Mortality) and (“Post-menopause”).Results: Seven studies were included in this review. A total of 6276 deaths were reported. Only 3 out of 6 studies reported that there is a significant benefit between physical activity and reduction in breast cancer-specific mortality. Contrarily, all studies reported that there is a significant benefit between physical activity and overall mortality reduction, but at a certain intensity level. Conclusions: Our data suggest that physical activity, whether pre-diagnosis or post-diagnosis, is associated with a better prognosis of breast cancer in postmenopausal women.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86036566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Curative radiation therapy for locally advanced pancreatic ductal adenocarcinoma (PDAC) is difficult when the tumor is in contact with the colon. In this regard, MRI-guided radiation therapy (MRgRT) provides real-time MRI during radiation therapy, resulting in highdose radiation delivery to the target while avoiding surrounding organs at risk (OARs), such as the intestinal tract. Case Presentation: A 94-year-old woman with locally advanced PDAC in the pancreatic tail underwent high-dose (72 Gy/30 fractions) real-time hypo-fractionated MRgRT to avoid irradiation of the colon. Three months after MRgRT, her serum CA 19-9 level normalized, and the tumor regressed completely. No adverse event or recurrence was noted during the six-month follow-up period.Conclusions: High-dose hypo-fractionated MRgRT may be a treatment option for a patient with locally advanced PDAC of the pancreatic tail, which is in contact with the colon.
{"title":"Real-Time MRI-guided Radiation Therapy for Locally Advanced Pancreatic Tail Cancer in Contact with The Colon","authors":"Y. Hama, E. Tate","doi":"10.33371/ijoc.v17i1.947","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.947","url":null,"abstract":"Introduction: Curative radiation therapy for locally advanced pancreatic ductal adenocarcinoma (PDAC) is difficult when the tumor is in contact with the colon. In this regard, MRI-guided radiation therapy (MRgRT) provides real-time MRI during radiation therapy, resulting in highdose radiation delivery to the target while avoiding surrounding organs at risk (OARs), such as the intestinal tract. Case Presentation: A 94-year-old woman with locally advanced PDAC in the pancreatic tail underwent high-dose (72 Gy/30 fractions) real-time hypo-fractionated MRgRT to avoid irradiation of the colon. Three months after MRgRT, her serum CA 19-9 level normalized, and the tumor regressed completely. No adverse event or recurrence was noted during the six-month follow-up period.Conclusions: High-dose hypo-fractionated MRgRT may be a treatment option for a patient with locally advanced PDAC of the pancreatic tail, which is in contact with the colon.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80649193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-28DOI: 10.33371/ijoc.v17i1.1022
E. Suzanna, A. Adisasmita, Pradnya Sri Rahayu, G. Shalmont
Background: Pelvic cavity is formed by the bones of pelvic organs where there are many system organs. Pelvic cavity cancer incidence in Jakarta from 2005 to 2007 was 13.96/100.000 population. In “Dharmais” National Cancer Hospital (DNCH), the frequency in 1993-2007 was 26% of all cancer. The purpose of the research is to find an overview of epidemiological (age group, gender, domicile, educational, marital status, tumor location) and clinical (symptoms and stage) cancer pelvic cavity. Methods: This cross-sectional study used the medical records of patients registered with DNCH as new cases and diagnosed by microscopic examination during 2005-2007. The study population is a case of cancer with the diagnosis of the location of the primary tumor in the pelvic cavity area. The sample calculation used a precision formula and obtained a minimum sample of 323. The data collection used questionnaires and obtained 326 cases. The data were analyzed using SPSS 26.0 with Chi-square test (α = 0.05).Results: Pelvic cavity cancer is a major problem in females (91.1%) with peak ages 45-59. Variations of clinical features in males and females were 24 and 35 symptomatic. In males, the most common clinical feature is dark/blood stool (41.38%), generally on rectal cancer, followed by weight loss (20.69%) which overlaps at five organs. In females, the most common clinical features are vaginal bleeding (43.77%), and vaginal spotting (13.47%), which occurs in cervix cancer, followed by abdominal pain (13.47%) that overlaps in six organs. Conclusions: Cancer, especially primary tumors of the pelvic cavity, is not a “silent killer” disease because the clinical picture can appear at an early stage. This study also provides a common clinical picture in patients with primary tumors in the pelvic cavity even though they are in one cavity. The clinical picture that appears is specific according to the primary tumor. In addition, some symptoms are possessed by various organs, so they are nonspecific.
{"title":"Various Clinical Overviews in Pelvic Cavity Cancer In “Dharmais” National Cancer Hospital (DNCH)","authors":"E. Suzanna, A. Adisasmita, Pradnya Sri Rahayu, G. Shalmont","doi":"10.33371/ijoc.v17i1.1022","DOIUrl":"https://doi.org/10.33371/ijoc.v17i1.1022","url":null,"abstract":"Background: Pelvic cavity is formed by the bones of pelvic organs where there are many system organs. Pelvic cavity cancer incidence in Jakarta from 2005 to 2007 was 13.96/100.000 population. In “Dharmais” National Cancer Hospital (DNCH), the frequency in 1993-2007 was 26% of all cancer. The purpose of the research is to find an overview of epidemiological (age group, gender, domicile, educational, marital status, tumor location) and clinical (symptoms and stage) cancer pelvic cavity. Methods: This cross-sectional study used the medical records of patients registered with DNCH as new cases and diagnosed by microscopic examination during 2005-2007. The study population is a case of cancer with the diagnosis of the location of the primary tumor in the pelvic cavity area. The sample calculation used a precision formula and obtained a minimum sample of 323. The data collection used questionnaires and obtained 326 cases. The data were analyzed using SPSS 26.0 with Chi-square test (α = 0.05).Results: Pelvic cavity cancer is a major problem in females (91.1%) with peak ages 45-59. Variations of clinical features in males and females were 24 and 35 symptomatic. In males, the most common clinical feature is dark/blood stool (41.38%), generally on rectal cancer, followed by weight loss (20.69%) which overlaps at five organs. In females, the most common clinical features are vaginal bleeding (43.77%), and vaginal spotting (13.47%), which occurs in cervix cancer, followed by abdominal pain (13.47%) that overlaps in six organs. Conclusions: Cancer, especially primary tumors of the pelvic cavity, is not a “silent killer” disease because the clinical picture can appear at an early stage. This study also provides a common clinical picture in patients with primary tumors in the pelvic cavity even though they are in one cavity. The clinical picture that appears is specific according to the primary tumor. In addition, some symptoms are possessed by various organs, so they are nonspecific.","PeriodicalId":13489,"journal":{"name":"Indonesian Journal of Cancer","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78037113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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