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Negative Predictors of Tooth Extraction in the Management of Odontogenic Sinusitis in a Japanese Patient Population: A Retrospective Study. 日本牙源性鼻窦炎患者拔牙的负面预测因素:一项回顾性研究。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1791492
Kazuhiro Hirasawa, Koji Otsuka, Renako Tomaru, Naoki Ikehata, Kiyoaki Tsukahara

Introduction  There are no clear guidelines for deciding between endoscopic sinus surgery and tooth extraction for the treatment of odontogenic sinusitis. Furthermore, tooth extraction does not necessarily improve sinusitis and eventually results in additional endoscopic sinus surgery. Objective  The present study aimed to retrospectively investigate negative predictive factors of tooth extraction for odontogenic sinusitis. Methods  In total, 22 patients with odontogenic sinusitis, who underwent tooth extraction between April 2017 and March 2021, were included. The patients were divided into the improved (n = 15) and non-improved (n = 7) groups. Subsequently, the two groups were compared. Results  A higher percentage of patients in the non-improved group had polyps in the middle nasal meatus ( p  = 0.0008), higher Lund-Mackay score (LMS) ( p  = 0.0008), and apical lesions penetrating the maxillary sinus ( p  = 0.113). Patients with middle nasal meatus polyps, with LMS ≥ 7, or with a combination of apical lesions penetrating the maxillary sinus and LMS ≥ 5, were less likely to see improvement in sinusitis with tooth extraction. Conclusion  Tooth extraction as the initial intervention for odontogenic sinusitis presents a higher risk of failure, particularly in cases in which polyps are present in the middle nasal meatus, with LMS ≥ 7, or with a combination of apical lesions penetrating the maxillary sinus and LMS ≥ 5.

在治疗牙源性鼻窦炎时,对于选择内窥镜鼻窦手术还是拔牙并没有明确的指导方针。此外,拔牙并不一定能改善鼻窦炎,并最终导致额外的内窥镜鼻窦手术。目的回顾性研究牙源性鼻窦炎拔牙的不良预测因素。方法纳入2017年4月至2021年3月期间接受拔牙治疗的22例牙源性鼻窦炎患者。将患者分为改善组(n = 15)和非改善组(n = 7)。随后,对两组进行比较。结果未改善组鼻中道息肉发生率较高(p = 0.0008),隆德-麦基评分(LMS)较高(p = 0.0008),鼻尖病变穿透上颌窦(p = 0.113)。LMS≥7的中鼻道息肉患者,或LMS≥5的根尖病变穿透上颌窦的合并患者,拔牙后鼻窦炎的改善可能性较小。结论牙源性鼻窦炎的初始干预拔牙失败的风险较高,特别是在LMS≥7的中鼻道息肉,或LMS≥5的根尖病变穿透上颌窦的情况下。
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引用次数: 0
Stapedotomy or Stapedectomy: Does It Really Matter? 镫骨切除术还是镫骨切除术?这真的重要吗?
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1792086
Francisco Teixeira-Marques, Rita Vaz Osório, Mónica Teixeira, Joana Rebelo, Sandra Gerós, Diamantino Helena, António Faria de Almeida, Pedro Oliveira

Introduction  Otosclerosis leads to stapes fixation and consequent conductive hearing loss. Surgery is the mainstay of treatment, and it can be achieved through small fenestra stapedotomy or stapedectomy. Despite the first being favored by most, evidence supporting its superiority over the latter remains inconclusive. Objective  To assess the hearing outcomes and complications of stapes surgery performed in a series of patients with otosclerosis and compare the results of stapedotomy with stapedectomy. Methods  A retrospective study of 134 ears in 125 otosclerosis patients undergoing primary stapes surgery was conducted. Patients underwent either stapedotomy or stapedectomy, and outcomes were compared using pre- and postoperative audiometric data and complication rates. Results  Most cases (81%) underwent stapedotomy. Both techniques resulted in significant improvement in air-bone gap (ABG) and speech recognition threshold (SRT) postoperatively, with no significant difference between them. Complication rates were comparable between techniques, with no statistical difference in postoperative complications. Conclusion  Both stapedotomy and stapedectomy offer favorable hearing outcomes with low complication rates in otosclerosis patients. While stapedotomy remains the preferred technique, if the initial plan shifts to a stapedectomy, surgeons should remain composed and confident in a good hearing outcome.

耳硬化导致镫骨固定和传导性听力丧失。手术是治疗的主要手段,可通过小窗镫骨切除术或镫骨切除术来实现。尽管前者受到大多数人的青睐,但支持其优于后者的证据仍然没有定论。目的评价镫骨切除术治疗耳硬化症患者的听力效果及并发症,并比较镫骨切除术与镫骨切除术的效果。方法对125例行初级镫骨手术的耳硬化患者134耳进行回顾性分析。患者接受镫骨切除术或镫骨切除术,使用术前和术后听力学数据和并发症发生率比较结果。结果多数病例(81%)行镫骨切开术。两种技术均可显著改善术后的气骨间隙(ABG)和语音识别阈值(SRT),两者之间无显著差异。两种技术之间的并发症发生率具有可比性,术后并发症无统计学差异。结论镫骨切除术和镫骨切除术对耳硬化症患者的听力效果良好,并发症发生率低。虽然镫骨切除术仍然是首选的技术,但如果最初的计划转变为镫骨切除术,外科医生应该保持镇静,并对良好的听力结果充满信心。
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引用次数: 0
Transoral Drug-Induced Sleep Endoscopy: A Useful Complementary Tool in Sleep Surgery. 经口药物诱导睡眠内窥镜:睡眠手术中一种有用的补充工具。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1788768
Ahmed Elsobki, Mohammed Elshaer, Hassan Ghabn, Mohamed E El-Deeb, Luci Suliman

Introduction  Drug-induced sleep endoscopy (DISE) is performed widely, and several studies have demonstrated its validity as it provides clinical information not available by routine clinical inspection alone. Objective  This study aims to evaluate the role of transoral drug-induced sleep endoscopy (DISE) in the evaluation of tongue-palate (TP) interaction and its impact on surgical outcomes. Methods  A total of 42 patients with known obstructive sleep apnea syndrome (OSAS) were classified into two groups according to TP interaction (the absence of space between tongue and palate with the visual impression that the tongue is pushing the soft palate) into +ve and -ve TP interaction. Snoring according to the visual analogue scale (VAS), the Epworth Sleepiness Scale (ESS), and sleep study data were recorded before and after the pharyngoplasty operation. Results  There was a statistically significant difference between studied groups postoperative regarding minimal oxygen saturation, snoring index, apnea-hypopnea index (AHI), the ESS, and visual analogue scale of snoring ( p  = 0.003*, p  < 0.001*, p  < 0.001*, p  = 0.004*, and p  = 0.003*, respectively). It displayed a marked higher average improvement among cases with -ve than in those with +ve TP interaction in terms of snoring index, AHI, and ESS. Conclusion  The Transoral DISE Has A Valuable Role In Evaluating And Assessing TP Interaction And Its Importance On Surgical Outcomes. Cases With Positive TP Interaction Show Poor Response To Isolated Palatopharyngeal Expansion And Need Further Analysis To Create A Better Treatment Plan And Improve Outcomes.

药物诱导睡眠内窥镜(Drug-induced sleep endoscopy,简称DISE)被广泛应用,一些研究已经证明了其有效性,因为它提供了常规临床检查无法获得的临床信息。目的探讨经口药物诱导睡眠内镜(DISE)在评估舌腭相互作用中的作用及其对手术结果的影响。方法将42例已知的阻塞性睡眠呼吸暂停综合征(OSAS)患者根据舌腭相互作用(舌与腭之间没有空间,舌推软腭的视觉印象)分为+ve和-ve TP相互作用两组。根据视觉模拟量表(VAS)、Epworth嗜睡量表(ESS)和睡眠研究数据记录咽成形术前后的打鼾情况。结果两组患者术后最低血氧饱和度、鼾症指数、呼吸暂停低通气指数(AHI)、ESS评分、鼾症视觉模拟评分差异均有统计学意义(p = 0.003*、p = 0.004*、p = 0.003*)。在打鼾指数、AHI和ESS方面,与+ve TP交互作用的患者相比,-ve TP交互作用的患者的平均改善程度明显更高。结论经口胸腔镜在评价和评估TP相互作用及其对手术结果的重要性方面具有重要意义。TP相互作用阳性的病例对孤立腭咽扩张反应较差,需要进一步分析以制定更好的治疗计划并改善结果。
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引用次数: 0
Postoperative Hearing Outcomes and Usefulness of Endoscopy-Assisted Tympanoplasty in Pars Tensa Cholesteatoma. 内窥镜辅助鼓室成形术治疗紧张部胆脂瘤的术后听力效果及疗效。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1792016
Takaomi Kurioka, Kunio Mizutari

Introduction  In recent years, transcanal endoscopic ear surgery (TEES) has gained widespread recognition as an excellent surgical field for blind spots such as the sinus tympani (ST) when compared to microscopic ear surgery (MES). Objective  To investigate the postoperative hearing results for pars tensa cholesteatoma and the indications for utilizing endoscopy. Methods  The medical records of 16 patients (10 men and 6 women) with pars tensa cholesteatoma, who received initial surgical treatment between 2018 and 2022, were reviewed. We performed MES, TEES, or endoscopy-assisted MES (dual approach) depending on the pathological involvement in the mastoid cavity and ST. Results  The mean age of the patients was 45 years, and the surgical techniques utilized were MES in 2 cases, TEES in 7 cases, and dual approach in 7 cases. The preoperative pathological classification was stage I in 3 patients and stage II in 13 patients. The overall surgical success rates of postoperative hearing outcomes were 69% and 50% (1/2 patients) in the TEES group, 71% (5/7 patients) in the MES group, and 71% (5/7 patients) in the dual approach group. The successful cases (n = 11) were significantly younger and demonstrated better mastoid pneumatization than unsuccessful cases (n = 5). Conclusion  Endoscopy-assisted MES is appropriate for treating pars tensa cholesteatoma when pathological involvement is present at the deep bottom of the ST. Early surgical intervention and good eustachian tube function are crucial for improving hearing prognosis. Transcanal endoscopic ear surgery can be particularly useful in identifying and removing residual cholesteatoma within the ST.

近年来,与耳镜手术(MES)相比,经鼻内窥镜耳部手术(TEES)作为治疗鼓室窦(ST)等盲点的优秀手术领域得到了广泛的认可。目的探讨张力部胆脂瘤术后听力效果及内镜应用的适应证。方法回顾性分析2018 ~ 2022年首次手术治疗的16例紧张部胆脂瘤患者的病历,其中男10例,女6例。结果患者平均年龄45岁,采用MES 2例,tee 7例,双入路7例。手术方式为MES 2例,tee 7例,双入路7例。术前病理分型为I期3例,II期13例。tee组术后听力预后总体手术成功率为69%和50%(1/2例),MES组为71%(5/7例),双入路组为71%(5/7例)。成功病例(n = 11)明显比不成功病例(n = 5)更年轻,乳突肺气化效果更好。结论内镜辅助下MES治疗st深底病变的紧张部胆脂瘤是合适的,早期手术干预和良好的咽鼓管功能是改善听力预后的关键。经鼻内窥镜耳部手术在识别和切除ST内残留的胆脂瘤方面特别有用。
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引用次数: 0
Incidence, Risk Factors and Outcomes of Urinary Tract Infections among Patients Undergoing Thyroidectomy: Insights from the ACS-NSQIP. 甲状腺切除术患者尿路感染的发生率、危险因素和结局:来自ACS-NSQIP的见解
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1788769
Usama Waqar, Warda Ahmed, Zoha Zahid Fazal, Ahmad Areeb Chaudhry, Haissan Iftikhar, Afsheen Ziauddin, Syed Akbar Abbas

Introduction  Urinary tract infections (UTIs) represent a rare postoperative complication following thyroidectomy. Objective  This study aimed to assess the clinicodemographic factors associated with the development of UTIs and subsequent outcomes among patients undergoing thyroidectomy. Methods  This retrospective study used the National Surgical Quality Improvement Program (NSQIP) database to analyze patients who underwent thyroidectomy from 2005 to 2019. Multivariable logistic regression models were used to identify risk factors and associations of UTIs with postoperative morbidity and mortality. Results  In a cohort of 180,373 identified thyroidectomy patients, 0.28% contracted a UTI. Significant risk factors associated with UTIs included age > 60 years (adjusted odds ratio [OR] 2.187, 95% confidence interval [CI] 1.618-2.956), female gender (OR 1.767, 95% CI 1.372-2.278), American Society of Anesthesiologists (ASA) Classification 3 to 5 (OR 1.463, 95% CI 1.185-1.805), partially (OR 4.267, 95% CI 2.510-7.253) or totally dependent functional health status (OR 9.658, 95% CI 4.170-22.370), pulmonary disease (OR1.907, 95% CI 1.295-2.808), chronic steroid therapy (OR 1.649, 95% CI 1.076-2.527), inpatient procedure (OR 1.507, 95% CI 1.251-1.814), and operative time > 150 minutes (OR 1.449, 95% CI 1.027-2.044). Additionally, UTIs were independently associated with postoperative complications, including pulmonary, vascular, or cardiac complication; stroke; acute renal failure; infectious complications; sepsis; septic shock; pneumonia; prolonged length of stay; unplanned reoperation; and mortality. Conclusion  While UTIs are rare after thyroidectomy, they carry a significant burden on patient outcomes. Preoperative optimization of comorbidities and reducing operative times may help mitigate the risk of UTIs. Optimized care for postoperative UTI patients is also recommended to prevent complications and improve outcomes.

摘要尿路感染是甲状腺切除术后罕见的并发症。目的本研究旨在评估甲状腺切除术患者中与尿路感染发展及后续结局相关的临床人口学因素。方法采用美国国家手术质量改进计划(NSQIP)数据库,对2005 - 2019年甲状腺切除术患者进行回顾性研究。采用多变量logistic回归模型确定尿路感染的危险因素以及尿路感染与术后发病率和死亡率的关系。结果在180373例甲状腺切除术患者中,0.28%的患者感染了尿路感染。与尿路感染相关的重要危险因素包括:年龄0 ~ 60岁(校正优势比[OR] 2.187, 95%可信区间[CI] 1.618 ~ 2.956)、女性(OR 1.767, 95% CI 1.372 ~ 2.278)、美国麻醉医师学会(ASA)分类3 ~ 5级(OR 1.463, 95% CI 1.185 ~ 1.805)、部分(OR 4.267, 95% CI 2.550 ~ 7.253)或完全依赖的功能健康状况(OR 9.658, 95% CI 4.170 ~ 22.370)、肺部疾病(OR1.907, 95% CI 1.295 ~ 2.808)、慢性类固醇治疗(OR 1.649、95% CI 1.076-2.527),住院手术(OR 1.507, 95% CI 1.251-1.814)和手术时间bb0 - 150分钟(OR 1.449, 95% CI 1.027-2.044)。此外,尿路感染与术后并发症独立相关,包括肺、血管或心脏并发症;中风;急性肾衰竭;感染性并发症;脓毒症;脓毒性休克;肺炎;逗留:逗留时间的延长;意外的再次手术;和死亡率。结论虽然甲状腺切除术后尿路感染很少见,但对患者预后有很大影响。术前优化合并症和减少手术时间可能有助于降低尿路感染的风险。对术后尿路感染患者的优化护理也被推荐用于预防并发症和改善预后。
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引用次数: 0
Obstructive Salivary Gland Disorders - A Malaysian Patient Series. 阻塞性唾液腺疾病--马来西亚患者系列。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-25 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1786833
Sethu Thakachy Subha, Malina Osman, Prepageran Narayanan

Introduction  Obstructive salivary gland disease is a frequently encountered clinical entity that can present to various health practitioners. Obstructive sialadenitis can lead to recurrent infections and debilitating quality-of-life issues. Objective  There is a paucity of published data regarding obstructive salivary disorders among the multiracial Asian population. The present study aimed to determine the demographic pattern and risk factors of obstructive salivary gland disorders with the goal of better management of this condition. Methods  A retrospective cross-sectional study was conducted at a tertiary institution over a period of 5 years. Results  A total of 256 (9.84 for every 1,000) patients were found to have salivary disorders, 10% of who were diagnosed to have obstructive disorder. Among the obstructive salivary disorders, 76% had sialolithiasis, 19% had recurrent parotitis, and 1 patient had chronic sialadenitis. We observed a small female preponderance for obstructive salivary disorders. This study revealed that smoking is a significant risk factor ( p  = 0.041; prevalence ratio = 2.54, 95% confidence interval 1.12-5.78), and smokers were 2.5 times more likely to develop obstructive salivary disorders. There was no statistical correlation between the prevalence and other risk factors like infection, dehydration, intake of medications, history of diabetes mellitus, radiotherapy, and autoimmune disorders. Conclusion  Our study results demonstrated that the prevalence of obstructive salivary gland disorders was 0.1%. This study provided a better understanding of the prevalence and risk factors of obstructive salivary disorders, which facilitate timely management and improves quality of life.

导言:阻塞性唾液腺疾病是临床上经常遇到的一种疾病,可出现在不同的医疗从业人员身上。阻塞性唾液腺炎可导致反复感染和生活质量下降。目的 有关多种族亚裔人群阻塞性唾液腺疾病的公开数据很少。本研究旨在确定阻塞性唾液腺疾病的人口统计学模式和风险因素,以便更好地治疗这种疾病。方法 在一家三级医院进行了一项为期 5 年的回顾性横断面研究。结果 共发现 256 名(每 1,000 人中有 9.84 名)患者患有唾液腺疾病,其中 10% 被诊断为阻塞性唾液腺疾病。在唾液阻塞性疾病中,76%患有霰粒肿,19%患有复发性腮腺炎,1 名患者患有慢性唾液腺炎。我们观察到,涎腺阻塞性疾病患者中女性占少数。这项研究显示,吸烟是一个重要的风险因素(P = 0.041;患病率比 = 2.54,95% 置信区间为 1.12-5.78),吸烟者患阻塞性唾液腺疾病的几率是正常人的 2.5 倍。发病率与感染、脱水、药物摄入、糖尿病史、放疗和自身免疫性疾病等其他风险因素之间没有统计学相关性。结论 我们的研究结果表明,阻塞性唾液腺疾病的发病率为 0.1%。这项研究使人们对阻塞性唾液腺疾病的发病率和风险因素有了更深入的了解,从而有助于及时治疗和提高生活质量。
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引用次数: 0
Dysphagia: Focus in Diagnosis. 吞咽困难:诊断重点。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-25 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1791749
Geraldo Pereira Jotz
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引用次数: 0
Do Anatomical Variations of Sphenoid Sinus Influence Sella Exposure and Residual Disease in Pituitary Surgery? - A Study in an Indian Population. 蝶窦的解剖变异会影响垂体手术中的蝶窦暴露和残留疾病吗?- 印度人群研究。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-25 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1788313
Aparna Gopalakrishnan, Sivaraman Ganesan, Andi Sadayandi Ramesh, Ananthakrishnan Ramesh, Lokesh Kumar Penubarathi, Kalaiarasi Raja, Jijitha Lakshmanan, Akshat Khushwaha, Koshika Kaushal, Arun Alexander

Introduction  Endoscopic transsphenoidal surgery (ETS) is the standard practice in pituitary surgeries. The sellar exposure becomes the main factor which determines the residual disease in ETS. Not many studies can be found in the literature on the influence of anatomical variations of the sphenoid on intraoperative sella exposure. Objective  The aim of the current study is to ascertain whether sphenoid sinus variations play a role in sellar exposure and residual tumor volume. Methods  This is a prospective study conducted in a south Indian tertiary care center between June 2020 to June 2022, with 21 study participants who were scheduled to have ETS. The relation of preoperative computed tomography (CT) and magnetic resonance imaging (MRI) parameters with the intraoperative area of sellar exposure and residual tumor volume was evaluated. Results  Sphenoid sinus dimensions, like presellar width (mean = 1.89 ± 0.51 cm), maximum width (mean = 2.94 ± 1.09 cm), presellar depth (mean = 1.14 ± 0.55 cm), suprasellar depth (mean = 1.08 ± 0.24 cm), infrasellar depth (mean = 2.36 ± 0.92 cm), presellar height (mean = 2.22 ± 0.47 cm), or the 9 internal carotid artery (ICA)-related measures, did not have any correlation with the mean intraoperative area of sellar exposure (0.57 ± 0.28 cm 2 ). Also, the adequacy of sellar exposure did not relate to the residual tumor. Preoperative tumor volume was found to be higher (20.2 [55.3-13.2] cm 3 ) in patients with residual tumor compared with those with no residual tumor (5.9 [6.8-5.2] cm 3 ). Tumor extension had a significant association with the residual tumor volume. Conclusion  According to the present study, anatomical variations of the sphenoid sinus do not influence the adequacy of sellar exposure. Further studies need to be undertaken concerning residual tumor volume as well as preoperative tumor volume and extension.

引言 内窥镜经蝶手术(ETS)是垂体手术的标准做法。在 ETS 中,蝶鞍暴露是决定残留疾病的主要因素。关于蝶鞍解剖变异对术中蝶鞍暴露影响的研究文献并不多。目的 本研究旨在确定蝶窦变异是否对蝶窦暴露和残余肿瘤体积有影响。方法 这是一项前瞻性研究,于 2020 年 6 月至 2022 年 6 月期间在印度南部的一家三级医疗中心进行,共有 21 名计划接受 ETS 的研究参与者。评估术前计算机断层扫描(CT)和磁共振成像(MRI)参数与术中蝶窦暴露面积和残余肿瘤体积的关系。结果 蝶窦尺寸,如蝶窦前宽(平均 = 1.89 ± 0.51 厘米)、最大宽度(平均 = 2.94 ± 1.09 厘米)、蝶窦前深(平均 = 1.14 ± 0.55 厘米)、蝶窦上深(平均 = 1.08 ± 0.24 cm)、髌下深度(平均 = 2.36 ± 0.92 cm)、髌前高度(平均 = 2.22 ± 0.47 cm)或 9 个颈内动脉(ICA)相关测量值与术中平均蝶鞍暴露面积(0.57 ± 0.28 cm 2)没有任何相关性。此外,蝶鞍暴露是否充分与残余肿瘤也没有关系。与无残留肿瘤的患者(5.9 [6.8-5.2] cm 3)相比,有残留肿瘤的患者术前肿瘤体积更高(20.2 [55.3-13.2] cm 3)。肿瘤的扩展与残留肿瘤体积有显著关系。结论 根据本研究,蝶窦的解剖变异不会影响蝶窦暴露的充分性。关于残余肿瘤体积以及术前肿瘤体积和扩展情况,还需要进一步研究。
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引用次数: 0
Efficacy of Expansion Pharyngoplasty without Drug-induced Sleep Endoscopy Screening in Obstructive Sleep Apnea. 无需药物诱导睡眠内窥镜筛查的扩张性咽成形术对阻塞性睡眠呼吸暂停的疗效。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-25 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1782630
Rafael Tenor, Juan Miguel Palomeque-Vera, Angel Bandera-López, Pilar Cuellar, Manuel Oliva-Domínguez

Introduction  Expansion sphincter pharyngoplasty has been shown to be a good alternative to continuous pressure devices in patients with moderate to severe obstructive sleep apnea. On the other hand, drug-induced sleep endoscopy provides information on the pattern of collapse in obstructive sleep apnea, although it is unclear whether this information improves the surgical outcomes. Objective  To evaluate the success rate obtained when performing expansion sphincter pharyngoplasty on a group of patients diagnosed with moderate to severe obstructive sleep apnea who were not previously selected by drug-induced sleep endoscopy. Methods  We present a series of patients with moderate to severe obstructive sleep apnea who underwent surgery. Pre- and postoperative home sleep apnea tests were performed. The success rate was calculated, and we assessed whether there were statistically significant pre- and postoperative differences in the apnea-hypopnea index and oximetry values. Results  In total, 20 patients were included, and the surgical success rate was of 80%. Statistically significant improvements were demonstrated in the mean apnea-hypopnea index (from 40.25 ± 15.18 events/hour to 13.14 ± 13.82 events/hour; p  < 0. 0001), the mean oximetric data (from 26.3 ± 12.97 desaturations/hour to 13.57 ± 15.02 desaturations/hour; p  = 0.034), and in the mean percentage of total sleep time in which the patient had less than 90% of saturation (from 8.64 ± 9.25% to 4.4 ± 7.76%; p  = 0.028). Conclusion  The results showed significant improvements in the apnea-hypopnea index and in the oximetric data, with a surgical success rate of 80%, despite the lack of prior drug-induced sleep endoscopy screening.

导言 对中重度阻塞性睡眠呼吸暂停患者而言,扩张括约肌咽成形术已被证明是持续加压装置的良好替代方案。另一方面,药物诱导睡眠内窥镜检查可提供阻塞性睡眠呼吸暂停患者塌陷模式的信息,但目前尚不清楚这些信息是否能改善手术效果。目的 评估对一组被诊断为中重度阻塞性睡眠呼吸暂停的患者实施扩张括约肌咽成形术的成功率,这些患者之前未通过药物诱导睡眠内窥镜检查进行筛选。方法 我们介绍了一系列接受手术治疗的中重度阻塞性睡眠呼吸暂停患者。术前和术后进行了家庭睡眠呼吸检测。我们计算了成功率,并评估了呼吸暂停-低通气指数和血氧饱和度值在术前和术后是否存在显著的统计学差异。结果 共纳入 20 名患者,手术成功率为 80%。平均呼吸暂停-低通气指数(从 40.25 ± 15.18 次/小时降至 13.14 ± 13.82 次/小时;P = 0.034)和患者睡眠饱和度低于 90% 的平均总睡眠时间百分比(从 8.64 ± 9.25% 降至 4.4 ± 7.76%;P = 0.028)均有明显改善。结论 结果显示,尽管之前没有进行过药物诱导睡眠内窥镜筛查,但呼吸暂停-低通气指数和血氧饱和度数据均有明显改善,手术成功率达 80%。
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引用次数: 0
Results of a New Treatment Protocol for Sudden Sensorineural Hearing Loss Using Betamethasone for Intratympanic Therapy. 使用倍他米松进行鼓室内治疗突发性感音神经性听力损失的新治疗方案的结果。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-25 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1788779
Paula Tardim Lopes, Jessica Almeida, Ricardo Ferreira Bento

Introduction  Sudden sensorineural hearing loss (SSNHL) is defined as a rapid sensation of hearing impairment in one or both ears. Based on its personal impact on patients, the present study advances the analysis of new treatments for the prompt recognition and management of SSNHL, with higher chances of improvements in terms of hearing recovery and quality of life of the patients. Objective  To describe the intratympanic (IT) corticoid infiltration technique, to demonstrate the efficacy of betamethasone injection as a sequential treatment in patients whose initial systemic steroid treatment failed, as well as to compare its use in different treatment periods. Methods  The present clinical trial was conducted with 37 patients referred to our office with the diagnosis of SSNHL, from September 2019 to May 2022, who provided informed consent to participate. Results  Even dividing the analysis of increasing the pure tone average (PTA) or speech recognition threshold (SRT) between the difference into initiation of the salvage therapy in up to 15 days of the sudden deafness event, and between 15 days and 3 months of the event, we did not find any difference in hearing improvement. Conclusion  Intratympanic corticosteroid therapy is prescribed when conventional therapy fails or when there is a limitation to the use of corticosteroids due to the presence of systemic disorders. As such, new drugs, such as bethametasone, are studied and show promising results.

导言:突发性感音神经性听力损失(SSNHL)是指单耳或双耳迅速感觉到听力受损。基于其对患者个人的影响,本研究推进了对新疗法的分析,以便及时识别和处理 SSNHL,从而提高患者听力恢复和生活质量的机会。目的 描述鼓室内皮质类固醇浸润技术,证明倍他米松注射液作为初始全身类固醇治疗失败患者的连续治疗方法的疗效,并比较其在不同治疗时期的使用情况。方法 本临床试验于 2019 年 9 月至 2022 年 5 月期间对 37 名转诊至我院确诊为 SSNHL 的患者进行了研究,这些患者在知情同意的情况下参与了试验。结果 即使将提高纯音平均值(PTA)或言语识别阈值(SRT)的分析分为突发性耳聋事件发生后 15 天内和事件发生后 15 天至 3 个月内开始抢救性治疗的差异,我们也没有发现听力改善方面的任何差异。结论 当常规治疗失败或因存在全身性疾病而限制使用皮质类固醇时,可采用鼓室内皮质类固醇治疗。因此,对新药(如倍他米松)进行了研究,并显示出良好的效果。
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引用次数: 0
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International Archives of Otorhinolaryngology
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