首页 > 最新文献

International Archives of Otorhinolaryngology最新文献

英文 中文
A Simplified Protocol for Tracheostomy Decannulation in Patients Weaned off Prolonged Mechanical Ventilation. 为长期机械通气断奶患者解除气管插管的简化方案。
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-04-01 DOI: 10.1055/s-0043-1776720
K Devaraja, C S Majitha, Kailesh Pujary, Dipak Ranjan Nayak, Shwethapriya Rao

Introduction  The criteria for the removal of the tracheostomy tube (decannulation) vary from center to center. Some perform an endoscopic evaluation under anesthesia or computed tomography, which adds to the cost and discomfort. We use a simple two-part protocol to determine the eligibility and carry out the decannulation: part I consists of airway and swallowing assessment through an office-based flexible laryngotracheoscopy, and part II involves a tracheostomy capping trial. Objective  The primary objective was to determine the safety and efficacy of the simplified decannulation protocol followed at our center among the patients who were weaned off the mechanical ventilator and exhibited good swallowing function clinically. Methods  Of the patients considered for decannulation between November 1st, 2018, and October 31st, 2020, those who had undergone tracheostomy for prolonged mechanical ventilation were included. The efficacy to predict successful decannulation was calculated by the decannulation rate among patients who had been deemed eligible for decannulation in part I of the protocol, and the safety profile was defined by the protocol's ability to correctly predict the chances of risk-free decannulation among those submitted to part II of the protocol. Results  Among the 48 patients included (mean age: 46.5 years; male-to-female ratio: 3:1), the efficacy of our protocol in predicting the successful decannulation was of 87.5%, and it was was safe or reliable in 95.45%. Also, in our cohort, the decannulation success and the duration of tracheotomy dependence were significantly affected by the neurological status of the patients. Conclusion  The decannulation protocol consisting of office-based flexible laryngotracheoscopy and capping trial of the tracheostomy tube can safely and effectively aid the decannulation process.

导言:拔除气管造口管(取消封管)的标准因医疗中心而异。有些中心在麻醉或计算机断层扫描下进行内窥镜评估,这增加了费用和不适感。我们采用一个简单的两部分方案来确定是否符合条件并实施拔管:第一部分包括通过诊室柔性喉气管镜进行气道和吞咽评估,第二部分包括气管造口封堵试验。目的 主要目的是确定本中心对已脱离机械呼吸机并在临床上表现出良好吞咽功能的患者所采用的简化气管切开方案的安全性和有效性。方法 在 2018 年 11 月 1 日至 2020 年 10 月 31 日期间考虑停用的患者中,纳入了因长期机械通气而接受气管切开术的患者。根据方案第一部分中被认为符合终止阉割条件的患者的终止阉割率计算预测成功终止阉割的有效性,根据方案正确预测提交方案第二部分的患者中无风险终止阉割机会的能力定义安全性概况。结果 在纳入的 48 名患者中(平均年龄:46.5 岁;男女比例:3:1),我们的方案在预测成功拔管方面的有效率为 87.5%,在 95.45% 的患者中是安全或可靠的。此外,在我们的队列中,气管切开的成功率和气管切开依赖的持续时间受到患者神经状况的显著影响。结论 由诊室柔性喉气管镜检查和气管造口导管封盖试验组成的封堵方案可以安全有效地帮助封堵过程。
{"title":"A Simplified Protocol for Tracheostomy Decannulation in Patients Weaned off Prolonged Mechanical Ventilation.","authors":"K Devaraja, C S Majitha, Kailesh Pujary, Dipak Ranjan Nayak, Shwethapriya Rao","doi":"10.1055/s-0043-1776720","DOIUrl":"https://doi.org/10.1055/s-0043-1776720","url":null,"abstract":"<p><p><b>Introduction</b>  The criteria for the removal of the tracheostomy tube (decannulation) vary from center to center. Some perform an endoscopic evaluation under anesthesia or computed tomography, which adds to the cost and discomfort. We use a simple two-part protocol to determine the eligibility and carry out the decannulation: part I consists of airway and swallowing assessment through an office-based flexible laryngotracheoscopy, and part II involves a tracheostomy capping trial. <b>Objective</b>  The primary objective was to determine the safety and efficacy of the simplified decannulation protocol followed at our center among the patients who were weaned off the mechanical ventilator and exhibited good swallowing function clinically. <b>Methods</b>  Of the patients considered for decannulation between November 1st, 2018, and October 31st, 2020, those who had undergone tracheostomy for prolonged mechanical ventilation were included. The efficacy to predict successful decannulation was calculated by the decannulation rate among patients who had been deemed eligible for decannulation in part I of the protocol, and the safety profile was defined by the protocol's ability to correctly predict the chances of risk-free decannulation among those submitted to part II of the protocol. <b>Results</b>  Among the 48 patients included (mean age: 46.5 years; male-to-female ratio: 3:1), the efficacy of our protocol in predicting the successful decannulation was of 87.5%, and it was was safe or reliable in 95.45%. Also, in our cohort, the decannulation success and the duration of tracheotomy dependence were significantly affected by the neurological status of the patients. <b>Conclusion</b>  The decannulation protocol consisting of office-based flexible laryngotracheoscopy and capping trial of the tracheostomy tube can safely and effectively aid the decannulation process.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11008947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Manifestations of Wegener Granulomatosis in Iranian Ethnicities Using the K-Means Algorithm: A Descriptive Study. 使用 K-Means 算法分析伊朗各民族韦格纳肉芽肿病的临床表现:描述性研究
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0043-1767803
Fahimeh Khedmatkon, Samira Alesaeidi, Fatemeh Hajialiasgari, Jaleh Shoshtarian Malak

Introduction  Wegener granulomatosis (WG) appears with clinical symptoms, including recurrent respiratory infection, renal manifestations, and nonspecific systemic symptoms. Objective  To study the clinical manifestations of WG in Iranian ethnicities, and data on 164 patients were recorded from 2013 to 2018. Methods  The data included demographics, symptoms, and the Birmingham Vasculitis Activity Score (BVAS). The symptoms involved the following sites: the nose, sinus, glottis, ears, lungs, kidneys, eyes, central nervous system, mucous membranes, skin, heart, stomach, intestine, as well as general symptoms. The clinical manifestations of nine ethnicities were analyzed. Results  In total, 48% of the patients were male and 51% were female, with a median age of 51 years. The BVAS was of 15.4, the sites most involved were the sinus ( n  = 155), nose ( n  = 126), lungs ( n  = 125), and ears ( n  = 107). Gastrointestinal ( n  = 14) and cardiac ( n  = 7) involvement were less common. Among the patients, 48.17% were Persian, 13.41% were Azari, 11.17% were Gilaki, 11.17% were Kurd, and 10.9% were Lor. Conclusion  Our findings indicated that the sinus, nose, lungs, and ears were the sites most involved, and gastrointestinal and cardiac involvement were less common. In the present study, involvement of the upper and lower respiratory tract was higher than that reported in Western and Asian case series. Moreover, we report for the first time that, in all patients with ear involvement, the left ear was the first to be affected. The clinical manifestations among Iranian ethnicities were not different, and the Gilaki ethnicity had the highest BVAS, mostly because the weather was humid; therefore, in Iran, in areas with humidity, the rate of the disease was higher.

导言 韦格纳肉芽肿病(WG)出现的临床症状包括反复呼吸道感染、肾脏表现和非特异性全身症状。目的 研究WG在伊朗种族中的临床表现,记录2013年至2018年164名患者的数据。方法 数据包括人口统计学、症状和伯明翰血管炎活动评分(BVAS)。症状涉及以下部位:鼻、鼻窦、声门、耳、肺、肾、眼、中枢神经系统、粘膜、皮肤、心脏、胃、肠以及全身症状。对九个种族的临床表现进行了分析。结果 48%的患者为男性,51%为女性,中位年龄为 51 岁。BVAS为15.4,受累部位最多的是鼻窦(155人)、鼻子(126人)、肺部(125人)和耳朵(107人)。胃肠道(14 例)和心脏(7 例)受累较少。患者中 48.17% 为波斯人,13.41% 为阿扎里人,11.17% 为吉拉基人,11.17% 为库尔德人,10.9% 为洛尔人。结论 我们的研究结果表明,鼻窦、鼻、肺和耳是受累最多的部位,而胃肠道和心脏受累则较少见。在本研究中,上呼吸道和下呼吸道受累的比例高于西方和亚洲的系列病例。此外,我们还首次发现,在所有耳部受累的患者中,左耳最先受累。伊朗各民族的临床表现并无差异,吉拉基族的 BVAS 最高,这主要是因为伊朗天气潮湿;因此,在伊朗,潮湿地区的发病率较高。
{"title":"Clinical Manifestations of Wegener Granulomatosis in Iranian Ethnicities Using the K-Means Algorithm: A Descriptive Study.","authors":"Fahimeh Khedmatkon, Samira Alesaeidi, Fatemeh Hajialiasgari, Jaleh Shoshtarian Malak","doi":"10.1055/s-0043-1767803","DOIUrl":"10.1055/s-0043-1767803","url":null,"abstract":"<p><p><b>Introduction</b>  Wegener granulomatosis (WG) appears with clinical symptoms, including recurrent respiratory infection, renal manifestations, and nonspecific systemic symptoms. <b>Objective</b>  To study the clinical manifestations of WG in Iranian ethnicities, and data on 164 patients were recorded from 2013 to 2018. <b>Methods</b>  The data included demographics, symptoms, and the Birmingham Vasculitis Activity Score (BVAS). The symptoms involved the following sites: the nose, sinus, glottis, ears, lungs, kidneys, eyes, central nervous system, mucous membranes, skin, heart, stomach, intestine, as well as general symptoms. The clinical manifestations of nine ethnicities were analyzed. <b>Results</b>  In total, 48% of the patients were male and 51% were female, with a median age of 51 years. The BVAS was of 15.4, the sites most involved were the sinus ( <i>n</i>  = 155), nose ( <i>n</i>  = 126), lungs ( <i>n</i>  = 125), and ears ( <i>n</i>  = 107). Gastrointestinal ( <i>n</i>  = 14) and cardiac ( <i>n</i>  = 7) involvement were less common. Among the patients, 48.17% were Persian, 13.41% were Azari, 11.17% were Gilaki, 11.17% were Kurd, and 10.9% were Lor. <b>Conclusion</b>  Our findings indicated that the sinus, nose, lungs, and ears were the sites most involved, and gastrointestinal and cardiac involvement were less common. In the present study, involvement of the upper and lower respiratory tract was higher than that reported in Western and Asian case series. Moreover, we report for the first time that, in all patients with ear involvement, the left ear was the first to be affected. The clinical manifestations among Iranian ethnicities were not different, and the Gilaki ethnicity had the highest BVAS, mostly because the weather was humid; therefore, in Iran, in areas with humidity, the rate of the disease was higher.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Prevalence of Dysphagia in Children with Laryngomalacia Pre and Postsupraglottoplasty: A Systematic Review with Meta-Analysis. 喉头成形术前后喉头畸形儿童吞咽困难的发生率:带 Meta 分析的系统性综述。
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0042-1755309
Eduarda Pinto Rossoni, Vanessa Souza Gigoski de Miranda, Lisiane De Rosa Barbosa

Introduction  Laryngomalacia is the most common congenital laryngeal alteration, with spontaneous resolution in most cases. However, in the face of more severe presentations of the disease, it is necessary to perform supraglottoplasty surgery. Studies have been dedicated to researching changes in swallowing in children with laryngomalacia before and after surgical intervention. Objectives  To identify the prevalence of oropharyngeal dysphagia in children with pre and postsupraglottoplasty laryngomalacia. Data Synthesis  A search strategy was developed with terms and entreterms to designate a population pediatric with laryngomalacia , exposure supraglottoplasty , and outcome frequency of dysphagia , adapted to the requirements of the main databases in the health area. The analysis of the records found was performed by two independent examiners and, in the end, 6 articles were included in the study. The articles found enabled a sample of 330 children with laryngomalacia, 311 of whom underwent supraglottoplasty. Among the included studies, 5 were grouped and meta-analyzed. After supraglottoplasty surgery, a 59% reduction in the prevalence of oropharyngeal dysphagia was identified, with high heterogeneity I 2  = 93%. Conclusion  Despite the heterogeneity of the sample, the supraglottoplasty procedure significantly reduces the prevalence of dysphagia in children with laryngomalacia.

导言 喉气肿是最常见的先天性喉部病变,大多数病例可自行缓解。但是,如果病情较为严重,则有必要进行声门上成形术。有研究专门探讨了喉气肿患儿在手术治疗前后吞咽功能的变化。目的 确定声门上型喉成形术前和术后儿童口咽吞咽困难的发生率。数据综合 根据卫生领域主要数据库的要求,制定了搜索策略,使用术语和词条来指定患有喉肌无力的儿科人群、喉上成形术暴露情况以及吞咽困难的结果频率。两名独立审查员对找到的记录进行了分析,最终有 6 篇文章被纳入研究范围。这些文章的样本包括 330 名喉头畸形儿童,其中 311 人接受了声门上成形术。在所纳入的研究中,有 5 篇文章进行了分组和荟萃分析。结果发现,接受声门上成形术后,口咽吞咽困难的发生率降低了 59%,异质性很高,I 2 = 93%。结论 尽管样本存在异质性,但喉上成形术可显著降低喉发育不全儿童吞咽困难的发生率。
{"title":"The Prevalence of Dysphagia in Children with Laryngomalacia Pre and Postsupraglottoplasty: A Systematic Review with Meta-Analysis.","authors":"Eduarda Pinto Rossoni, Vanessa Souza Gigoski de Miranda, Lisiane De Rosa Barbosa","doi":"10.1055/s-0042-1755309","DOIUrl":"10.1055/s-0042-1755309","url":null,"abstract":"<p><p><b>Introduction</b>  Laryngomalacia is the most common congenital laryngeal alteration, with spontaneous resolution in most cases. However, in the face of more severe presentations of the disease, it is necessary to perform supraglottoplasty surgery. Studies have been dedicated to researching changes in swallowing in children with laryngomalacia before and after surgical intervention. <b>Objectives</b>  To identify the prevalence of oropharyngeal dysphagia in children with pre and postsupraglottoplasty laryngomalacia. <b>Data Synthesis</b>  A search strategy was developed with terms and entreterms to designate a population <i>pediatric with laryngomalacia</i> , exposure <i>supraglottoplasty</i> , and outcome <i>frequency of dysphagia</i> , adapted to the requirements of the main databases in the health area. The analysis of the records found was performed by two independent examiners and, in the end, 6 articles were included in the study. The articles found enabled a sample of 330 children with laryngomalacia, 311 of whom underwent supraglottoplasty. Among the included studies, 5 were grouped and meta-analyzed. After supraglottoplasty surgery, a 59% reduction in the prevalence of oropharyngeal dysphagia was identified, with high heterogeneity I <sup>2</sup>  = 93%. <b>Conclusion</b>  Despite the heterogeneity of the sample, the supraglottoplasty procedure significantly reduces the prevalence of dysphagia in children with laryngomalacia.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Endoscopic Stapedectomy: Systematic Review. 内窥镜镫骨切除术的结果:系统性综述。
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0043-1761171
Ahmed Nabil Elsamnody, Amr Hamdino Yousef, Mohamed Salah Taha

Introduction  Stapes surgery was traditionally performed with the use of microscopy either through postauricular, endaural or transcanal approaches. Endoscopic stapedectomy ushered a revolution as a new technique with less complications. Objective  To review the outcomes of endoscopic stapes surgery with an emphasis on intraoperative and postoperative clinical and audiological results. Data Synthesis  A literature review on the PubMed, Web of Science, Scopus, the Cochrane Library, and Embase databases was conducted. Endoscopic stapes surgery or stapedotomy were the main keywords used, and we searched for studies and research published from January 2015 to October 2021. Articles on endoscopic stapes surgery were included, and qualitative and descriptive analyses of the studies and outcomes data regarding audiometric changes and postoperative complications were conducted. Articles including patients with cholesteatoma were excluded. A total of 122 studies were retrieved for qualitative and descriptive analyses and to measure the outcomes of endoscopic stapedotomy; only 12 studies met the inclusion criteria, and the rest was excluded. The meta-analysis revealed a statistically significant difference in hearing improvement. The gain in air-bone gap ranged from 9 dB to 16 dB. A low rate of operative and postoperative complications was reported. Conclusions  Endoscopic stapes surgery appears to be a reasonable alternative to microscopic stapes surgery, with shorter operative times, low complication rate, and significant hearing improvement. The endoscopic technique enabled a better visualization and less scutum drilling, which was confirmed by all included studies.

简介:传统的镫骨手术是通过耳后、耳内或经肛门的显微镜进行的。内窥镜镫骨切除术作为一种并发症较少的新技术带来了一场革命。目的 回顾内窥镜镫骨手术的结果,重点是术中、术后的临床和听力结果。数据综述 在 PubMed、Web of Science、Scopus、Cochrane Library 和 Embase 数据库中进行了文献综述。内窥镜镫骨手术或镫骨切开术是我们使用的主要关键词,我们搜索了2015年1月至2021年10月期间发表的研究。我们纳入了有关内窥镜镫骨手术的文章,并对研究和有关听力变化及术后并发症的结果数据进行了定性和描述性分析。不包括胆脂瘤患者的文章。共检索了122项研究,对其进行定性和描述性分析,并对内窥镜镫骨切开术的结果进行测量;只有12项研究符合纳入标准,其余研究被排除在外。荟萃分析表明,听力改善方面存在显著的统计学差异。气骨间隙的增益从 9 分贝到 16 分贝不等。手术和术后并发症的发生率较低。结论 内窥镜镫骨手术似乎是显微镜镫骨手术的合理替代方案,手术时间短,并发症发生率低,听力改善显著。内窥镜技术可实现更好的可视化,减少颅骨钻孔,这一点在所有纳入的研究中都得到了证实。
{"title":"Outcomes of Endoscopic Stapedectomy: Systematic Review.","authors":"Ahmed Nabil Elsamnody, Amr Hamdino Yousef, Mohamed Salah Taha","doi":"10.1055/s-0043-1761171","DOIUrl":"10.1055/s-0043-1761171","url":null,"abstract":"<p><p><b>Introduction</b>  Stapes surgery was traditionally performed with the use of microscopy either through postauricular, endaural or transcanal approaches. Endoscopic stapedectomy ushered a revolution as a new technique with less complications. <b>Objective</b>  To review the outcomes of endoscopic stapes surgery with an emphasis on intraoperative and postoperative clinical and audiological results. <b>Data Synthesis</b>  A literature review on the PubMed, Web of Science, Scopus, the Cochrane Library, and Embase databases was conducted. <i>Endoscopic stapes surgery</i> or <i>stapedotomy</i> were the main keywords used, and we searched for studies and research published from January 2015 to October 2021. Articles on endoscopic stapes surgery were included, and qualitative and descriptive analyses of the studies and outcomes data regarding audiometric changes and postoperative complications were conducted. Articles including patients with cholesteatoma were excluded. A total of 122 studies were retrieved for qualitative and descriptive analyses and to measure the outcomes of endoscopic stapedotomy; only 12 studies met the inclusion criteria, and the rest was excluded. The meta-analysis revealed a statistically significant difference in hearing improvement. The gain in air-bone gap ranged from 9 dB to 16 dB. A low rate of operative and postoperative complications was reported. <b>Conclusions</b>  Endoscopic stapes surgery appears to be a reasonable alternative to microscopic stapes surgery, with shorter operative times, low complication rate, and significant hearing improvement. The endoscopic technique enabled a better visualization and less scutum drilling, which was confirmed by all included studies.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Value of Endoscopic Exposure of Round Window in Cochlear Implant via Facial Recess. 通过面部凹陷在内窥镜下暴露人工耳蜗圆窗的价值。
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0043-1775811
Mena Maher Nassif, Islam Mohamed Hussein Darahem, Ahmed Abdelmoneim Teaima, Mustafa Mohamed Mustafa, Mohamed Saad Hassab Allah, Samer Ahmed Ibrahim

Introduction  Cochlear implantation has been considered as the best treatment in patients with severe to profound hearing loss unaidable with hearing aids. The main value of endoscope-assisted cochlear implantation is improved visibility of the RW Objective  to assess the value of endoscopic assisted CI surgery via facial recess approach without elevating tympanic anulus. Methods  This Prospective case series study non-randomized sample was performed on 50 patients with severe to profound hearing loss unaidable with hearing aids undergoing unilateral endoscopic assisted cochlear implant surgery with round window electrode insertion Results  There were 23 male and 27 female patients. Most of the cases were children (41 cases). Of those 50 patients, 39 were prelingually hearing impaired. Four cases had various inner ear abnormalities. The standard mastoidectomy and Posterior Tympanotomy approach were used for all cases. Endoscopic identification of the RW through the PT enabled us to perform regular surgery in all cases. The current study concludes the difference between microscopic exposure and endoscopic exposure represented by Saint Tomas classification found that endoscopic exposure of round window classification is better represented by downgrading in the classification of round window exposure as type I 29(58%), type IIa 18(36%) type IIb 3 (6%) Non were type III by endoscopic exposure compared to microscopic exposure of round window is a type I 7(14%), type II 14(28%), type IIb 22(44%) and type III 7 (14%). Conclusion  Endoscopy proved a great value in exposure and identification of RW in CI surgery through posterior tympanotomy approach.

导言 人工耳蜗植入术一直被认为是无法使用助听器的重度到极重度听力损失患者的最佳治疗方法。内窥镜辅助人工耳蜗植入术的主要价值在于提高了人工耳蜗的可视性 目的 评估通过面部凹陷方法进行内窥镜辅助人工耳蜗植入手术的价值,而无需抬高鼓室。方法 对 50 名无法使用助听器的重度至极重度听力损失患者进行非随机抽样的前瞻性病例系列研究,这些患者接受了单侧内窥镜辅助人工耳蜗植入手术,并植入了圆窗电极。大多数病例为儿童(41 例)。在这 50 例患者中,39 例为舌前听力受损。4 例患者有各种内耳畸形。所有病例均采用标准乳突切除术和鼓室后切口法。内窥镜通过 PT 识别 RW 使我们能够对所有病例实施常规手术。目前的研究总结了以圣托马斯分类法为代表的显微镜下暴露和内窥镜下暴露之间的差异,发现内窥镜下暴露的圆窗分类法更好地代表了圆窗暴露的降级分类,即 I 型 29(58%)、IIa 型 18(36%)、IIb 型 3(6%),但内窥镜下暴露的圆窗与显微镜下暴露的圆窗相比,属于 III 型,即 I 型 7(14%)、II 型 14(28%)、IIb 型 22(44%)和 III 型 7(14%)。结论 在通过鼓室后切口进行的 CI 手术中,内窥镜在暴露和识别圆窗方面具有重要价值。
{"title":"The Value of Endoscopic Exposure of Round Window in Cochlear Implant via Facial Recess.","authors":"Mena Maher Nassif, Islam Mohamed Hussein Darahem, Ahmed Abdelmoneim Teaima, Mustafa Mohamed Mustafa, Mohamed Saad Hassab Allah, Samer Ahmed Ibrahim","doi":"10.1055/s-0043-1775811","DOIUrl":"10.1055/s-0043-1775811","url":null,"abstract":"<p><p><b>Introduction</b>  Cochlear implantation has been considered as the best treatment in patients with severe to profound hearing loss unaidable with hearing aids. The main value of endoscope-assisted cochlear implantation is improved visibility of the RW <b>Objective</b>  to assess the value of endoscopic assisted CI surgery via facial recess approach without elevating tympanic anulus. <b>Methods</b>  This Prospective case series study non-randomized sample was performed on 50 patients with severe to profound hearing loss unaidable with hearing aids undergoing unilateral endoscopic assisted cochlear implant surgery with round window electrode insertion <b>Results</b>  There were 23 male and 27 female patients. Most of the cases were children (41 cases). Of those 50 patients, 39 were prelingually hearing impaired. Four cases had various inner ear abnormalities. The standard mastoidectomy and Posterior Tympanotomy approach were used for all cases. Endoscopic identification of the RW through the PT enabled us to perform regular surgery in all cases. The current study concludes the difference between microscopic exposure and endoscopic exposure represented by Saint Tomas classification found that endoscopic exposure of round window classification is better represented by downgrading in the classification of round window exposure as type I 29(58%), type IIa 18(36%) type IIb 3 (6%) Non were type III by endoscopic exposure compared to microscopic exposure of round window is a type I 7(14%), type II 14(28%), type IIb 22(44%) and type III 7 (14%). <b>Conclusion</b>  Endoscopy proved a great value in exposure and identification of RW in CI surgery through posterior tympanotomy approach.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Voice and Temporal Auditory Processing in Elderly People: A Correlation Study. 老年人的声音和时态听觉处理:相关性研究
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0043-1768139
Mariana Batista de Souza Santos, Lílian Ferreira Muniz, Adriana de Oliveira Camargo Gomes, Cleide Fernandes Teixeira, Karina Paes Advíncula, Zulina Souza de Lira, Bruno Teixeira de Moares, Jonia Alves Lucena

Introduction  The voice and hearing can be affected to different degrees by aging, which can cause communication difficulties for elderly people. Vocal production requires effective temporal auditory processing at central levels within the nervous system, which can be compromised by the aging process. Objective  To analyze the correlation between voice and temporal auditory processing in older adults. Materials and Methods  A total of 40 elderly people aged 60 years or older were subdivided into 2 groups according to the presence or absence of vocal symptoms measured by the Voice Symptom Scale. All of the participants were submitted to auditory temporal tests, vocal self-assessment, and acoustic and perceptual auditory analyses of voice. Results  Most of the subjects assessed had decreased voice intensity and normal variability in terms of vocal quality. The performance was normal in the Pitch Pattern Sequence test and altered in the Random Gap Detection test. In the Masking Period Pattern test, the detection thresholds for the target signal were increased in the presence of masking in different temporal target signal positions. Only pitch differed between the two groups. There were differences between the genders regarding frequency, shimmer, the overall severity of the alteration, and roughness. There was a correlation regarding temporal resolution ability and the overall severity of the alteration and roughness of the voice. Conclusion  There is a central auditory impairment in temporal resolution which is correlated with vocal alterations in the elderly.

导言:嗓音和听力会因衰老而受到不同程度的影响,从而导致老年人交流困难。发声需要神经系统中枢层面有效的时间听觉处理,而这可能会因衰老过程而受到影响。目的 分析老年人发声与时间听觉处理之间的相关性。材料与方法 根据嗓音症状量表(Voice Symptom Scale)测量的嗓音症状存在与否,将 40 名 60 岁或以上的老年人分为两组。所有受试者均接受了听觉时间测试、发声自我评估以及嗓音声学和知觉听觉分析。结果 大多数受测者的声音强度有所下降,声音质量的可变性正常。在音高模式序列测试中,受试者的表现正常,而在随机间隙检测测试中,受试者的表现有所改变。在掩蔽周期模式测试中,目标信号的检测阈值在不同时间目标信号位置存在掩蔽的情况下均有所提高。两组之间只有音高存在差异。在频率、光泽、整体改变的严重程度和粗糙度方面,性别之间存在差异。时间分辨能力与声音变化的整体严重程度和粗糙度存在相关性。结论 老年人的听觉中枢在时间分辨率方面存在障碍,这与嗓音改变有关。
{"title":"Voice and Temporal Auditory Processing in Elderly People: A Correlation Study.","authors":"Mariana Batista de Souza Santos, Lílian Ferreira Muniz, Adriana de Oliveira Camargo Gomes, Cleide Fernandes Teixeira, Karina Paes Advíncula, Zulina Souza de Lira, Bruno Teixeira de Moares, Jonia Alves Lucena","doi":"10.1055/s-0043-1768139","DOIUrl":"10.1055/s-0043-1768139","url":null,"abstract":"<p><p><b>Introduction</b>  The voice and hearing can be affected to different degrees by aging, which can cause communication difficulties for elderly people. Vocal production requires effective temporal auditory processing at central levels within the nervous system, which can be compromised by the aging process. <b>Objective</b>  To analyze the correlation between voice and temporal auditory processing in older adults. <b>Materials and Methods</b>  A total of 40 elderly people aged 60 years or older were subdivided into 2 groups according to the presence or absence of vocal symptoms measured by the Voice Symptom Scale. All of the participants were submitted to auditory temporal tests, vocal self-assessment, and acoustic and perceptual auditory analyses of voice. <b>Results</b>  Most of the subjects assessed had decreased voice intensity and normal variability in terms of vocal quality. The performance was normal in the Pitch Pattern Sequence test and altered in the Random Gap Detection test. In the Masking Period Pattern test, the detection thresholds for the target signal were increased in the presence of masking in different temporal target signal positions. Only pitch differed between the two groups. There were differences between the genders regarding frequency, shimmer, the overall severity of the alteration, and roughness. There was a correlation regarding temporal resolution ability and the overall severity of the alteration and roughness of the voice. <b>Conclusion</b>  There is a central auditory impairment in temporal resolution which is correlated with vocal alterations in the elderly.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cannabidiol (CBD): Potential Use in Otorhinolaryngology. 大麻二酚(CBD):耳鼻喉科的潜在用途。
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0043-1777857
Geraldo Pereira Jotz, Rafael Scorsatto Ortiz, Renata Pereira Limberger, Flavio Anastácio de Oliveira Camargo
{"title":"Cannabidiol (CBD): Potential Use in Otorhinolaryngology.","authors":"Geraldo Pereira Jotz, Rafael Scorsatto Ortiz, Renata Pereira Limberger, Flavio Anastácio de Oliveira Camargo","doi":"10.1055/s-0043-1777857","DOIUrl":"10.1055/s-0043-1777857","url":null,"abstract":"","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Late Bilateral Sequential Cochlear Implant and Quality of Life. 晚期双侧序列人工耳蜗植入与生活质量
IF 1.1 Q3 Medicine Pub Date : 2024-02-05 eCollection Date: 2024-04-01 DOI: 10.1055/s-0043-1776721
Larissa Claret De Lima Mendes, Alda Borges, Fernanda Caldas, Juliano Passos Barbosa, Fayez Bahmad

Introduction  Hearing impairment is one of the main disorders that can interfere with the development of speech and language. In an individual, it can cause significant communication difficulties, social isolation, negative feelings, and depressive disorders. The hearing aids (HAs) and cochlear implant (CI) are options for profound and severe hearing loss, and the CI can be indicated for individuals who do not obtain benefits from HAs. Objective  To evaluate the quality of life of individuals who underwent sequential bilateral CIs with a long surgical interval between procedures. Methods  Fifteen patients, aged 8 to 70 years old, who underwent sequential bilateral CI, with an interval ≥ 4 years between surgeries, were evaluated. Quality of life was evaluated using three questionnaires: WHOQOL-BREF, SSQ-12 and HHIA in Portuguese. Results  The WHOQOL-BREF questionnaire showed that the study participants had a good quality of life in all domains assessed. According to the SSQ-12, few reported inability to listen in communication situations. Most individuals were classified as having medium disability by the HHIA, but the social and emotional effects did not significantly affect the quality of life. Conclusion  The use of questionnaires to assess the quality of life of patients with hearing impairment is a valuable tool to measure adaptation to CI. Patients undergoing bilateral sequential CI, even with a long interval between procedures, presented high indices of quality of life.

导言 听力障碍是影响言语和语言发展的主要疾病之一。听力障碍可导致严重的沟通障碍、社交孤立、负面情绪和抑郁症。助听器(HAs)和人工耳蜗(CI)是治疗极重度和严重听力损失的选择,而人工耳蜗则适用于无法从助听器中获益的患者。目的 评估连续接受双侧人工耳蜗植入术且手术间隔时间较长的患者的生活质量。方法 对 15 名年龄在 8 至 70 岁之间、接受过连续双侧 CI 手术且手术间隔时间≥ 4 年的患者进行评估。使用三种问卷对患者的生活质量进行了评估:WHOQOL-BREF、SSQ-12 和葡萄牙语 HHIA。结果 WHOQOL-BREF 问卷显示,研究参与者在所有评估领域的生活质量都很高。根据 SSQ-12,很少有人报告在交流场合无法倾听。在 HHIA 中,大多数人被归类为中度残疾,但社交和情感方面的影响对生活质量并无明显影响。结论 使用问卷评估听力障碍患者的生活质量是衡量其对 CI 适应情况的重要工具。接受双侧顺序 CI 的患者,即使手术间隔时间较长,其生活质量指数也很高。
{"title":"Late Bilateral Sequential Cochlear Implant and Quality of Life.","authors":"Larissa Claret De Lima Mendes, Alda Borges, Fernanda Caldas, Juliano Passos Barbosa, Fayez Bahmad","doi":"10.1055/s-0043-1776721","DOIUrl":"https://doi.org/10.1055/s-0043-1776721","url":null,"abstract":"<p><p><b>Introduction</b>  Hearing impairment is one of the main disorders that can interfere with the development of speech and language. In an individual, it can cause significant communication difficulties, social isolation, negative feelings, and depressive disorders. The hearing aids (HAs) and cochlear implant (CI) are options for profound and severe hearing loss, and the CI can be indicated for individuals who do not obtain benefits from HAs. <b>Objective</b>  To evaluate the quality of life of individuals who underwent sequential bilateral CIs with a long surgical interval between procedures. <b>Methods</b>  Fifteen patients, aged 8 to 70 years old, who underwent sequential bilateral CI, with an interval ≥ 4 years between surgeries, were evaluated. Quality of life was evaluated using three questionnaires: WHOQOL-BREF, SSQ-12 and HHIA in Portuguese. <b>Results</b>  The WHOQOL-BREF questionnaire showed that the study participants had a good quality of life in all domains assessed. According to the SSQ-12, few reported inability to listen in communication situations. Most individuals were classified as having medium disability by the HHIA, but the social and emotional effects did not significantly affect the quality of life. <b>Conclusion</b>  The use of questionnaires to assess the quality of life of patients with hearing impairment is a valuable tool to measure adaptation to CI. Patients undergoing bilateral sequential CI, even with a long interval between procedures, presented high indices of quality of life.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11008946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep and Learning: A Systematic Review. 睡眠与学习:系统回顾
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-02-05 eCollection Date: 2024-10-01 DOI: 10.1055/s-0043-1777294
Martha Lucía Gutiérrez Pérez, Juan Antonio Lugo Machado, Valeria Lozano Lavado, Diana Camila Navarro Pimiento

Introduction  Sleep deprivation has a great impact on the learning process in physicians in training. Therefore, inquiring on this phenomenon in the most recent investigations will facilitate the provision of evidence on the influence regarding the absence of sleep on the learning process in health personnel. Objectives  The aim of this systematic review is to review, analyze and discuss the current literature that shows the impact of sleep on the learning process on doctors in training. Data Synthesis  A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. A search of the existing literature between the years of 2000 and 2022 was performed in the PubMed and Elsevier databases, taking into account the inclusion criteria of articles in English or Spanish and the established timeframe. As a result, 128 articles distributed in the databases were obtained and 23 articles that met the inclusion criteria were selected. Conclusion  Sleep is a fundamental factor for the consolidation, processing and functioning of memory and learning. Health professionals are a population at risk of sleep deprivation, thus it is important to take into account the effects it has on patients and health personnel.

引言 睡眠不足对受训医生的学习过程有很大影响。因此,对这一现象进行最新调查将有助于提供证据,说明睡眠不足对医务人员学习过程的影响。目的 本系统性综述旨在回顾、分析和讨论显示睡眠对受训医生学习过程影响的现有文献。数据综述 根据《系统综述和元分析首选报告项目》(PRISMA)指南进行了系统综述。我们在 PubMed 和 Elsevier 数据库中对 2000 年至 2022 年间的现有文献进行了搜索,同时考虑到英语或西班牙语文章的纳入标准和既定的时间范围。结果,共获得 128 篇分布在数据库中的文章,并筛选出 23 篇符合纳入标准的文章。结论 睡眠是巩固、处理和发挥记忆与学习功能的基本因素。医务人员是睡眠不足的高危人群,因此必须考虑到睡眠不足对患者和医务人员的影响。
{"title":"Sleep and Learning: A Systematic Review.","authors":"Martha Lucía Gutiérrez Pérez, Juan Antonio Lugo Machado, Valeria Lozano Lavado, Diana Camila Navarro Pimiento","doi":"10.1055/s-0043-1777294","DOIUrl":"10.1055/s-0043-1777294","url":null,"abstract":"<p><p><b>Introduction</b>  Sleep deprivation has a great impact on the learning process in physicians in training. Therefore, inquiring on this phenomenon in the most recent investigations will facilitate the provision of evidence on the influence regarding the absence of sleep on the learning process in health personnel. <b>Objectives</b>  The aim of this systematic review is to review, analyze and discuss the current literature that shows the impact of sleep on the learning process on doctors in training. <b>Data Synthesis</b>  A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. A search of the existing literature between the years of 2000 and 2022 was performed in the PubMed and Elsevier databases, taking into account the inclusion criteria of articles in English or Spanish and the established timeframe. As a result, 128 articles distributed in the databases were obtained and 23 articles that met the inclusion criteria were selected. <b>Conclusion</b>  Sleep is a fundamental factor for the consolidation, processing and functioning of memory and learning. Health professionals are a population at risk of sleep deprivation, thus it is important to take into account the effects it has on patients and health personnel.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142516385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Covid-19-Associated Mucormycosis: Histopathology of the Deadly Fungal Infection 与 Covid-19 相关的粘孢子菌病:致命真菌感染的组织病理学
IF 1.1 Q3 Medicine Pub Date : 2024-01-24 DOI: 10.1055/s-0043-1776729
N. Anand, P. Srivastava, Ashish Chandra Agrawal, Nikhil Gupta, Anupam Das, Nuzhat Husain
Introduction Many patients suffered from rhino-orbital-cerebral mucormycosis during the coronavirus disease 2019 (COVID-19) pandemic in India. Diabetes is a known risk factor of COVID-19 infection and mucormycosis. Objective The present study was done to describe the clinical spectrum and histopathological findings of mucormycosis in COVID-19 patients and their outcomes. Methods A cross-sectional study was done over a period of two and half months. The biopsy samples or scrapings from sinonasal or periorbital tissue of 38 patients were analyzed. Hematoxylin & Eosin (H&E stain) slides were evaluated along with Grocott-Gomori methenamine–silver and Periodic acid–Schiff stains to highlight the fungal elements. Results The male to female ratio was 2.5:1, and the mean age of the subjects was 53 years old. A total of 68.4% (n = 26/38) of the patients had diabetes as a comorbidity, 84.2% (n = 32/38) had a history of steroid intake, and 55.3% (n = 21/38) were given supplemental oxygen during their treatment. The common presentations were nasal blockage, discharge, eye pain, headache, and altered mentation. The sites of biopsy were: nasal cavity 76.3% (n = 29/38), periorbital fat/orbit 21.1% (n = 8/38), maxillary sinus 15.8% (n = 6/38) and ethmoid sinus 13.2% (n = 5/38). In 76.3% (n = 29/38) cases, broad, irregular, nonseptate, and right-angle branching hyphae were seen on H&E-stained tissue sections. Conclusion COVID-19 led to various complications in individuals affected by it. Mucormycosis was one such lethal complication. An early diagnosis and prompt treatment is crucial to control the progression of the disease and improve outcomes.
导言:在印度冠状病毒病2019(COVID-19)大流行期间,许多患者患上了鼻眶脑粘液瘤病。糖尿病是COVID-19感染和粘液瘤病的已知风险因素。目的 本研究旨在描述 COVID-19 患者粘孢子菌病的临床表现、组织病理学结果及其预后。方法 进行了为期两个半月的横断面研究。对 38 名患者鼻窦或眶周组织的活检样本或刮片进行了分析。对血红素和伊红(H&E 染色)切片进行了评估,同时采用 Grocott-Gomori methenamine-silver 和 Periodic acid-Schiff 染色法来突出真菌成分。结果 男女比例为 2.5:1,受试者平均年龄为 53 岁。68.4%(26/38)的患者合并有糖尿病,84.2%(32/38)的患者有类固醇摄入史,55.3%(21/38)的患者在治疗过程中使用了氧气补充剂。常见症状为鼻塞、流鼻涕、眼痛、头痛和精神改变。活组织检查的部位为:鼻腔 76.3%(n = 29/38)、眶周脂肪/眼眶 21.1%(n = 8/38)、上颌窦 15.8%(n = 6/38)和筛窦 13.2%(n = 5/38)。在 76.3%(n = 29/38)的病例中,H&E 染色的组织切片上可见宽阔、不规则、无隔膜和直角分支的菌丝。结论 COVID-19 会导致患者出现各种并发症。粘孢子菌病就是其中一种致命的并发症。早期诊断和及时治疗对于控制病情发展和改善预后至关重要。
{"title":"Covid-19-Associated Mucormycosis: Histopathology of the Deadly Fungal Infection","authors":"N. Anand, P. Srivastava, Ashish Chandra Agrawal, Nikhil Gupta, Anupam Das, Nuzhat Husain","doi":"10.1055/s-0043-1776729","DOIUrl":"https://doi.org/10.1055/s-0043-1776729","url":null,"abstract":"\u0000 Introduction Many patients suffered from rhino-orbital-cerebral mucormycosis during the coronavirus disease 2019 (COVID-19) pandemic in India. Diabetes is a known risk factor of COVID-19 infection and mucormycosis.\u0000 Objective The present study was done to describe the clinical spectrum and histopathological findings of mucormycosis in COVID-19 patients and their outcomes.\u0000 Methods A cross-sectional study was done over a period of two and half months. The biopsy samples or scrapings from sinonasal or periorbital tissue of 38 patients were analyzed. Hematoxylin & Eosin (H&E stain) slides were evaluated along with Grocott-Gomori methenamine–silver and Periodic acid–Schiff stains to highlight the fungal elements.\u0000 Results The male to female ratio was 2.5:1, and the mean age of the subjects was 53 years old. A total of 68.4% (n = 26/38) of the patients had diabetes as a comorbidity, 84.2% (n = 32/38) had a history of steroid intake, and 55.3% (n = 21/38) were given supplemental oxygen during their treatment. The common presentations were nasal blockage, discharge, eye pain, headache, and altered mentation. The sites of biopsy were: nasal cavity 76.3% (n = 29/38), periorbital fat/orbit 21.1% (n = 8/38), maxillary sinus 15.8% (n = 6/38) and ethmoid sinus 13.2% (n = 5/38). In 76.3% (n = 29/38) cases, broad, irregular, nonseptate, and right-angle branching hyphae were seen on H&E-stained tissue sections.\u0000 Conclusion COVID-19 led to various complications in individuals affected by it. Mucormycosis was one such lethal complication. An early diagnosis and prompt treatment is crucial to control the progression of the disease and improve outcomes.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139602521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Archives of Otorhinolaryngology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1