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Evaluation of Quality of Life After Use the Virtual Reality in Patients with Neurodegenerative Disease. 评估神经退行性疾病患者使用虚拟现实技术后的生活质量。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-04-30 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1785681
Jéssica Spricigo Malisky, Bianca Lopes Cavalcante-Leão, Maria Izabel Severiano, Geslaine Janaina Bueno Dos Santos, Hélio Augusto Guizoni Teive, Maria Renata José, Cristiano Miranda de Araújo, Bianca Simone Zeigelboim

Introduction  Spinocerebellar ataxias (SCAs) are a heterogeneous group of neurodegenerative diseases. Objective  To evaluate the living standard of patients with SCA, by applying the Vestibular Disorders Activities of Daily Living Scale (VADL) and Activitiesspecific Balance Confidence Scale (ABC) questionnaires. Methods  An uncontrolled clinical trial study was conducted with 28 patients who underwent anamnesis, ENT evaluation, and vestibular assessment and the application of questionnaires VADL and ABC before and after rehabilitation with virtual reality. Results  The vestibular exam was altered in 64.3% of the cases. The result between the correlation of the VADL and ABC questionnaires showed significant results in all cases (p < 0.005). The correlation between the ages and disease length with the VADL and ABC questionnaires was significant in the T3 assessment (p = 0.015). The correlation between the disease length and the VADL questionnaire was significant in all cases (p < 0.005). The comparison of the vestibular rehabilitation result (T1 to T2) showed a significant difference for all the applied games, except for the ski slalom. The comparison of the vestibular rehabilitation result (T1 to T3) showed significant difference for all the applied games (p < 0.005) (1st assessment before the start of rehabilitation designated T1, after 10 rehabilitation sessions, considered T2 and, at the end of 20 rehabilitation sessions, called T3). Conclusion  We can point out a direct improvement in the living standard, reflected by the reduction of falls, better balance, and march, contributing to a higher self-confidence in patients in daily activities.

导言脊髓小脑性共济失调(SCA)是一种异质性神经退行性疾病。目的 通过应用前庭障碍日常生活活动量表(VADL)和特定活动平衡信心量表(ABC)问卷,评估 SCA 患者的生活水平。方法 对 28 名患者进行了一项非对照临床试验研究,这些患者在使用虚拟现实技术进行康复治疗之前和之后,接受了病史、耳鼻喉科评估、前庭评估以及 VADL 和 ABC 问卷调查。结果 64.3% 的病例的前庭检查有变化。在所有病例中,VADL 和 ABC 问卷的相关性结果均显示出显著的效果(p 结论 我们可以指出,跌倒次数的减少、平衡能力的提高和行进能力的增强,直接提高了患者的生活水平,有助于增强他们在日常活动中的自信心。
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引用次数: 0
The Use of Rhinomanometry in Mouth Breathing: A Systematic Review of the Literature. 鼻测量法在口呼吸中的应用:文献系统回顾。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-03-27 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1785199
Merly Fernanda Illera Castellanos, Hilton Justino da Silva, Silvio Ricardo Couto de Moura, Luciana de Barros Correia Fontes, Niedje Siqueira de Lima, Thiago Freire Pinto Bezerra, Daniele Andrade da Cunha

Introduction  Mouth breathing generates imbalances in the musculature, in craniofacial morphofunctionality, and in the stomatognathic system. Therefore, it is essential to make a diagnosis of mouth breathing through the quantitative assessment of nasal permeability, which can be performed through rhinomanometry. Objective  To investigate the effectiveness of rhinomanometry in the diagnosis of mouth breathing in pediatric patients through a systematic review of the literature. Data synthesis  The guiding question was: "Is the use of rhinomanometry as an assessment tool effective in the diagnosis of mouth breathing in pediatric patients?". We conducted a search on the following databases: Latin American and Caribbean Center on Health Sciences Information (BIREME), Latin American and Caribbean Health Sciences Literature (LILACS), PubMed/Medical Literature Analysis and Retrieval System Online (MEDLINE), Scientific Electronic Library Online (SciELO), Web of Science, and Science Direct. The Health Sciences Descriptors (Descritores em Ciências da Saúde, DECS, in Portuguese) and Medical Subjects Headings (MESH) were combined with the Boolean operator AND in the search strategy: rhinomanometry AND mouth breathing AND diagnosis AND nasal pressure AND nasal airflow AND nasal resistance . Observational cohort and cross-sectional studies that addressed the effectiveness of rhinomanometry in the diagnosis of mouth breathing were included. The reviewers independently extracted the information and scored the review quality based on the Physiotherapy Evidence Database (PEDro) scale and the grading of evidence levels according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. Of the 1,536 articles identified, only 3 were selected for the present review after the application of the eligibility criteria. Conclusion  There is great concern regarding the assessment of nasal function. There was a lack of standardization of rhinomanometry to test the effectiveness of nasal resistance as an aid in the diagnosis of breathing mode.

引言 口呼吸会导致肌肉组织、颅面部形态功能和口颌系统失衡。因此,必须通过鼻腔通透性的定量评估对口呼吸进行诊断,而鼻腔通透性的定量评估可通过鼻测量法进行。目的 通过对文献进行系统性回顾,研究鼻测量法在诊断儿童患者口呼吸方面的有效性。数据综述"使用鼻测量仪作为评估工具对诊断儿科患者的口呼吸是否有效?我们在以下数据库中进行了搜索:拉丁美洲和加勒比海健康科学信息中心 (BIREME)、拉丁美洲和加勒比海健康科学文献 (LILACS)、PubMed/医学文献分析和检索系统在线 (MEDLINE)、科学电子图书馆在线 (SciELO)、Web of Science 和 Science Direct。在检索策略中,将健康科学描述符(Descritores em Ciências da Saúde,葡萄牙语为 DECS)和医学主题词表(MESH)与布尔运算符 AND 结合在一起:鼻测量和口呼吸和诊断和鼻压力和鼻气流和鼻阻力。纳入了针对鼻测量法在口呼吸诊断中有效性的观察性队列研究和横断面研究。审稿人独立提取信息,并根据物理治疗证据数据库 (PEDro) 量表对综述质量进行评分,同时根据建议评估、发展和评价分级 (GRADE) 系统对证据等级进行分级。在确定的 1,536 篇文章中,只有 3 篇在适用资格标准后被选入本次综述。结论 鼻腔功能评估备受关注。鼻测量法缺乏标准化,无法测试鼻阻力作为呼吸模式诊断辅助工具的有效性。
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引用次数: 0
Assessment of Tracheostomy Tube Placement and Late Change Practices in an Academic Tertiary Care Center. 评估一家学术性三级护理中心的气管造口术置管和晚期更换实践。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-03-27 eCollection Date: 2024-07-01 DOI: 10.1055/s-0043-1776723
Christophe Abi Zeid Daou, Elsa Maria Chahine, Randa Barazi

Introduction  The optimal time for tracheostomy changes is unknown. Most surgeons opt to wait until five to seven days postoperatively, while more recent studies suggest that changes occurring as early as two to three days postoperatively are also safe. Objective  To evaluate the safety of changing the tracheostomy tube later than 14 days postoperatively. Methods  The charts of patients who underwent tracheostomy placement and change at a tertiary care center from 2015 to 2019 were retrospectively reviewed, and the subjects were divided into 2 cohorts (late and very late), depending on the time of the first tracheostomy change. Results  The study included 198 patients, 53 of whom aged between 0 and 18 years, and 145, aged > 18 years. The time until the first tracheostomy change was on average of 131.1 days. The most common indication for tracheostomy tube placement was prolonged intubation. Adverse events were observed in 30.8% of the cases (the most common being the formation of granulation tissue), a rate that does not differ much from the incidence reported in the literature (of 34% to 77%) when tracheostomy tubes are changed as early as 3 to 7 days postoperatively. There was no significant difference in the incidence of complications between patients undergoing late and very late changes ( p  = 0.688), or between pediatric and adult subjects ( p  = 0.36). There were no significant correlations regarding the time of the first or second change and the incidence of complications (r = -0.014; p  = 0.84 for the first change; and r = -0.57; p  = 0.64 for the second change). Conclusion  The late first tracheostomy tube change was safe and could save resources and decrease the financial burden of frequent changes. It is always crucial to provide adequate information about home tracheostomy care for patients.

导言:气管造口更换的最佳时间尚不清楚。大多数外科医生选择等到术后五到七天,而最近的研究表明,术后两到三天内更换气管造口管也是安全的。目的 评估术后 14 天后更换气管造口管的安全性。方法 回顾性审查 2015 年至 2019 年在一家三级医疗中心接受气管造口置入和更换的患者病历,并根据首次更换气管造口的时间将受试者分为 2 个队列(晚期和极晚期)。结果 研究共纳入 198 名患者,其中 53 人年龄在 0 至 18 岁之间,145 人年龄大于 18 岁。首次更换气管造口的时间平均为 131.1 天。放置气管造口管最常见的适应症是长时间插管。30.8%的病例出现了不良反应(最常见的是肉芽组织的形成),这一比例与文献中报道的术后3至7天就更换气管造口管的发生率(34%至77%)相差不大。晚换和极晚换气管造口管的患者并发症发生率无明显差异(P = 0.688),儿科和成人受试者的并发症发生率也无明显差异(P = 0.36)。第一次或第二次更换气管造口的时间与并发症的发生率无明显相关性(第一次更换气管造口的相关性为 r = -0.014;p = 0.84;第二次更换气管造口的相关性为 r = -0.57;p = 0.64)。结论 延迟首次气管造口管更换是安全的,可节省资源并减轻频繁更换的经济负担。为患者提供充分的家庭气管造口护理信息始终是至关重要的。
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引用次数: 0
Cephalometric Evaluation in Patients with Obstructive Sleep Apnea undergoing Lateral Pharyngoplasty. 对接受侧咽喉成形术的阻塞性睡眠呼吸暂停患者进行头颅测量评估。
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-03-06 eCollection Date: 2024-04-01 DOI: 10.1055/s-0043-1776718
Stephanie Regiane Prata Ferreira Zanco, Bruno Bernardo Duarte, Aurélio Rochael Almeida, José Alexandre Mendonça

Introduction  Lateral pharyngoplasty (LP) has shown promising results. Craniofacial deformity reduces the pharyngeal space, contributing to the etiopathogenesis. The analysis of craniofacial features can be performed using cephalometry. Objective  To verify if craniofacial deformity is associated with worse polysomnographic data in patients with obstructive sleep apnea (OSA), and to verify if the preoperative cephalometric parameters can interfere with the surgical success of the LP. Methods  The study included 21 patients with OSA aged between 18 and 65 years who underwent LP in a university hospital from 2015 to 2019. Polysomnography was performed postoperatively, after a minimum period of 6 months from the surgical procedure. In addition, a cephalometric evaluation was performed to assess craniofacial deformity, and to correlate it with the polysomnographic results. Results  The mean and median of all polysomnographic respiratory parameters improved postoperatively, especially the apnea-hypopnea index (AHI), which went from 40.15 to 16.60 events per hour ( p  = 0.001). Of the 21 patients, 15 showed improvements in the AHI postoperatively. As for the cephalometric evaluations, we found that the longer the distance between the hyoid bone and the mandibular plane, the greater the patient's preoperative AHI ( p  = 0.011). When assessing whether cephalometric changes related to craniofacial deformities influence the surgical outcome of LP, no correlation was found for any cephalometric measurement. Conclusion  The longer the distance between the hyoid bone and the mandibular plane, the greater the preoperative AHI, and LP was an effective OSA treatment. Cephalometric variables are not able to modify or determine the success of LP in apneic patients in the population assessed.

导言:侧咽成形术(LP)已经取得了良好的效果。颅面畸形缩小了咽部空间,是导致咽喉炎的病因之一。头颅测量法可对颅面特征进行分析。目的 验证颅面畸形是否与阻塞性睡眠呼吸暂停(OSA)患者较差的多导睡眠图数据有关,并验证术前头颅测量参数是否会干扰 LP 手术的成功。方法 该研究纳入了 21 名 OSA 患者,他们的年龄在 18 岁至 65 岁之间,于 2015 年至 2019 年期间在一家大学医院接受了 LP 手术。术后至少 6 个月后进行多导睡眠图检查。此外,还进行了头颅测量评估,以评估颅面畸形,并将其与多导睡眠图结果相关联。结果 所有多导睡眠图呼吸参数的平均值和中位数在术后均有所改善,尤其是呼吸暂停-低通气指数(AHI),从每小时 40.15 次下降到 16.60 次(P = 0.001)。在 21 名患者中,有 15 名患者的 AHI 在术后有所改善。在头颅测量评估方面,我们发现舌骨与下颌骨平面之间的距离越长,患者术前的 AHI 就越大(p = 0.011)。在评估与颅面畸形相关的头测量变化是否会影响 LP 的手术效果时,没有发现任何头测量值与之相关。结论 舌骨与下颌骨平面之间的距离越长,术前 AHI 越大,LP 是一种有效的 OSA 治疗方法。在所评估的人群中,头颅测量变量无法改变或决定对呼吸暂停患者进行 LP 治疗的成功与否。
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引用次数: 0
Endoscopic Evaluation after Conventional Adenoid Curettage. 传统腺样体切除术后的内窥镜评估
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-02-16 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1779434
Ahmed Abdelfattah Bayomy Nofal, Mohamed Abdelmohsen Alnemr, Ahmed Hassan Sweed, Alsayed Abdulmageed

Introduction  Adenoidectomy is one of the most common procedures performed by otolaryngologists. Traditional adenoid curettage is performed blindly, which can result in inadequate removal of the adenoid and injury to the surrounding structures. Objective  To perform transnasal endoscopic examinations to assess the nasopharynx after conventional curettage adenoidectomy. Methods  The present prospective study included 100 children with a mean age of 4.2 ± 3.07 years. It is composed of two steps: conventional curettage adenoidectomy by a resident trainee; and endoscopic evaluation of the nasopharynx through a 0° telescope to assess adenoidal remnants, injury to the surgical field or adjacent structures, and bleeding points. Results  Adenoid remnants were observed in 42% of the cases after conventional adenoid curettage in multiple locations, such as the roof of the nasopharynx over the choana (24%), the tubal tonsil (12%), the posterior pharyngeal wall (4%), and the posterior end of the nasal septum (2%). Injury to the surgical field and adjacent structures was observed in 46% of the cases (posterior pharyngeal wall: 23%; lateral pharyngeal wall: 11%; Passavant ridge: 10%; and the Eustachian tube orifice: 2%). Endoscopic bleeding was observed in 29% of the cases; 13% of the cases were from adenoid remnants, 10%, from the mucosa, and 6%, from the pharyngeal muscles. Bleeding was mild in 19% of the cases, moderate in 9%, and severe in 1%. Conclusion  Endoscopic evaluation of the nasopharynx following conventional adenoid curettage provides important data regarding adenoid remnants, injury to the surgical field or nearby structures, and bleeding points, which aids in the provision of optimal care and in the achievement of a better outcome.

导言:腺样体切除术是耳鼻喉科医生最常见的手术之一。传统的腺样体刮除术是盲目进行的,可能导致腺样体切除不充分和周围结构损伤。目的 通过经鼻内窥镜检查评估传统腺样体刮除术后的鼻咽部情况。方法 本前瞻性研究包括 100 名儿童,平均年龄为 4.2 ± 3.07 岁。研究包括两个步骤:由一名住院受训者进行常规刮治腺样体切除术;通过0°望远镜对鼻咽部进行内窥镜评估,以评估腺样体残留、手术区域或邻近结构的损伤以及出血点。结果 42% 的病例在常规腺样体刮除术后多个部位观察到腺样体残留,如鼻咽顶部咽喉部(24%)、输卵管扁桃体(12%)、咽后壁(4%)和鼻中隔后端(2%)。46%的病例观察到手术区域和邻近结构受到损伤(咽后壁:23%;咽侧壁:11%; Passavant脊:5%):咽后壁:23%;咽侧壁:11%;咽嵴:10%;咽鼓管口:2%):2%).29%的病例观察到内镜下出血,其中13%来自腺样体残留物,10%来自粘膜,6%来自咽部肌肉。19%的病例为轻度出血,9%为中度出血,1%为严重出血。结论 传统腺样体刮除术后的鼻咽部内窥镜评估提供了有关腺样体残留、手术区域或附近结构损伤以及出血点的重要数据,有助于提供最佳护理和取得更好的疗效。
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引用次数: 0
Rate and Causes of Unplanned Hospital Returns within 60 Days following Head and Neck Surgery. 头颈部手术后 60 天内计划外退院的比例和原因。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-02-16 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1779433
Mazin Merdad, Abdulsalam Alqutub, Ahmed Mogharbel, Abdullah Farid, Abdullah Bayazed, Abdulaziz Alghamdi, Yazeed Albogami, Rayan Alshehri, Majed N Alnefaie, Hanin A Alamoudi

Introduction  Unplanned hospital returns are frequent and may be preventable. Objective  To comprehend the reasons for unplanned hospital readmission and return to the Outpatient Department (OPD) and Emergency Department (ED) within 60 days after discharge following head and neck surgery (HNS) at a tertiary care center in Saudi Arabia. Methods  In the present retrospective study, the medical records of all patients who underwent HNS for benign and malignant conditions between January 2015 and June 2022 were reviewed in terms of demographic data, comorbidities, and reasons for hospital return. Results  Out of 1,030 cases, 119 (11.55%) returned to the hospital within 60 days after discharge, 19 of which (1.84%) were readmitted. In total, 90 (8.74%) patients returned to the OPD, and 29 (2.82%), to the ED. The common reasons for readmission included infections (26.32%) and neurological symptoms (21.05%). For OPD visits, the common causes were hematoma (20%) and neurological symptoms (14.44%). For ED returns, the frequent causes were neurological symptoms (20.69%) and equipment issues (17.24%). Compared with nonreadmitted patients, readmitted patients had a higher preoperative baseline health burden when examined using the American Society of Anesthesiologists (ASA) score ( p  = 0.004) and the Cumulative Illness Rating Scale (CIRS; p  = 0.002). Conclusion  The 60-day rates of unplanned hospital return to the OPD and ED were of 8.74% and 2.82% respectively, and 1.84% of the patients were readmitted. Hematoma, infections, and neurological symptoms were common causes. Addressing the common reasons may be beneficial to decrease postoperative hospital visits.

导言:非计划再次入院的情况经常发生,而且可能是可以预防的。目的 了解沙特阿拉伯一家三级医疗中心头颈部手术(HNS)出院后 60 天内非计划再入院以及重返门诊部(OPD)和急诊部(ED)的原因。方法 在本回顾性研究中,研究人员查阅了 2015 年 1 月至 2022 年 6 月期间所有因良性和恶性疾病接受头颈外科手术的患者的病历,包括人口统计学数据、合并症和复诊原因。结果 在 1030 个病例中,119 例(11.55%)在出院后 60 天内返回医院,其中 19 例(1.84%)再次入院。共有 90 名(8.74%)患者返回手术室,29 名(2.82%)返回急诊室。再次入院的常见原因包括感染(26.32%)和神经症状(21.05%)。在手术室就诊的患者中,常见原因是血肿(20%)和神经症状(14.44%)。就急诊室复诊而言,常见原因是神经系统症状(20.69%)和设备问题(17.24%)。与未入院患者相比,使用美国麻醉医师协会(ASA)评分(P = 0.004)和累积疾病评分量表(CIRS;P = 0.002)检查再入院患者的术前基线健康负担较高。结论 60 天内手术室和急诊室非计划返院率分别为 8.74% 和 2.82%,1.84% 的患者再次入院。血肿、感染和神经症状是常见原因。解决这些常见原因可能有利于减少术后住院次数。
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引用次数: 0
Olfaction and Quality of Life in Patients with Eosinophilic CRS Undergoing Endoscopic Sinus Surgery. 接受内窥镜鼻窦手术的嗜酸性粒细胞 CRS 患者的嗅觉和生活质量
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-02-16 eCollection Date: 2024-04-01 DOI: 10.1055/s-0043-1772494
Miguel Soares Tepedino, Richard Louis Voegels, Rogério Pezato, Andrew Thamboo, Eduardo Macoto Kosug, Ana Clara Miotello Ferrão, Raíssa de Figueiredo Neves, Valéria Maria Barcia Castilla, Luis Carlos Gregório

Introduction  Chronic rhinosinusitis (CRS) is a common inflammatory disease. This high prevalence leads to high direct and indirect public health costs, which include medical visits, laboratory tests and imaging, pharmacotherapy, hospitalizations, and surgical treatment. Furthermore, CRS has a substantial impact on patient quality of life, affecting productivity and being a common cause of absence from work CRS-associated olfactory dysfunction is highly prevalent, the actual effectiveness of surgical intervention remains inconsistent. Although there are studies evaluating the postoperative course of patients with eosinophilic Chronic rhinosinusitis (eCRS) treated with high-volume budesonide irrigation, there is little objective information regarding the impact of this intervention on olfactory status and quality of life. Objective  To conduct a pre- and postoperative analysis of olfaction and quality of life in patients with eCRS treated with surgical intervention followed by high-volume budesonide nasal irrigation. Methods  Prospective, descriptive, uncontrolled study of patients with eCRS. All patients underwent pre- and postoperative nasal endoscopy, SNOT-22 questionnaire, and the University of Pennsylvania Smell Identification Text (UPSIT), always by the same previously trained examiner. The SNOT-22 questionnaire and the UPSIT were readministered to all patients at 3 months, 6 months, and 1 year postoperatively, and scores compared with those obtained preoperatively. Results  Twenty patients were included in the study, 13 males and 7 females, between the ages of 23 and 65; 8 patients had comorbid asthma. Quantitative evaluation using the UPSIT test showed a significant improvement in olfaction 3 months after surgery, which remained 6 months and 1 year after surgery (p = 0.0063). There was no significant association between eosinophil concentrations in polypoid tissue and postoperative SNOT-22 and UPSIT results. Patients with tissue eosinophils >50 had a lower preoperative UPSIT score. As early as 3 months postoperatively, a significant improvement in quality of life was already noticeable, as represented by a decrease in SNOT-22 values, which persisted through the 1-year postoperative follow-up evaluation (p = 0.0005). Quantitative evaluation using the UPSIT test showed a significant improvement in olfaction 3 months after surgery, which remained 6 months and 1 year after surgery (p = 0.0063). Conclusion  Surgery effectively controlled eCRS in patients who adhered to high-volume budesonide nasal irrigation postoperatively. There were significant improvements in quality of life and olfaction, which persisted at least up to one year postoperatively.

导言:慢性鼻炎(CRS)是一种常见的炎症性疾病。这种高发病率导致了高昂的直接和间接公共卫生成本,其中包括就诊、实验室检查和影像学检查、药物治疗、住院治疗和手术治疗。此外,CRS 还严重影响患者的生活质量,影响工作效率,是缺勤的常见原因之一。CRS 相关的嗅觉功能障碍非常普遍,但手术干预的实际效果仍不一致。虽然有研究评估了嗜酸性粒细胞慢性鼻炎(eCRS)患者接受大量布地奈德冲洗治疗的术后疗程,但关于这种干预措施对嗅觉状态和生活质量的影响的客观信息却很少。目的 对接受手术治疗后进行大容量布地奈德鼻腔冲洗的 eCRS 患者的嗅觉和生活质量进行术前和术后分析。方法 对 eCRS 患者进行前瞻性、描述性、非对照研究。所有患者均接受了术前和术后鼻内窥镜检查、SNOT-22 问卷调查和宾夕法尼亚大学气味识别文本(UPSIT)测试,所有测试均由之前接受过培训的同一检查人员进行。所有患者在术后 3 个月、6 个月和 1 年时重新接受 SNOT-22 问卷和 UPSIT 测试,并将得分与术前进行比较。结果 研究共纳入 20 名患者,其中男性 13 名,女性 7 名,年龄在 23 岁至 65 岁之间;8 名患者合并有哮喘。使用 UPSIT 测试进行的定量评估显示,术后 3 个月嗅觉有明显改善,术后 6 个月和 1 年仍有改善(p = 0.0063)。息肉组织中的嗜酸性粒细胞浓度与术后 SNOT-22 和 UPSIT 结果之间没有明显关联。组织中嗜酸性粒细胞大于 50 的患者术前 UPSIT 评分较低。早在术后 3 个月,患者的生活质量就有了明显改善,这体现在 SNOT-22 值的降低上,这种改善一直持续到术后 1 年的随访评估(p = 0.0005)。使用 UPSIT 测试进行的定量评估显示,术后 3 个月嗅觉明显改善,术后 6 个月和术后 1 年仍然如此(p = 0.0063)。结论 对于术后坚持使用大量布地奈德鼻腔冲洗的患者,手术能有效控制 eCRS。患者的生活质量和嗅觉得到了明显改善,这种改善至少持续到术后一年。
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引用次数: 0
Study of Speech Recognition in Noise and Working Memory in Adults and Elderly with Normal Hearing. 研究听力正常的成年人和老年人在噪音中的语音识别能力和工作记忆能力。
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-02-16 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1779432
Daniela Aiko Akashi, Maria Cecília Martinelli

Introduction  In clinical practice, patients with the same degree and configuration of hearing loss, or even with normal audiometric thresholds, present substantially different performances in terms of speech perception. This probably happens because other factors, in addition to auditory sensitivity, interfere with speech perception. Thus, studies are needed to investigate the performance of listeners in unfavorable listening conditions to identify the processes that interfere in the speech perception of these subjects. Objective  To verify the influence of age, temporal processing, and working memory on speech recognition in noise. Methods  Thirty-eight adult and elderly individuals with normal hearing thresholds participated in the study. Participants were divided into two groups: The adult group (G1), composed of 10 individuals aged 21 to 33 years, and the elderly group (G2), with 28 participants aged 60 to 81 years. They underwent audiological assessment with the Portuguese Sentence List Test, Gaps-in-Noise test, Digit Span Memory test, Running Span Task, Corsi Block-Tapping test, and Visual Pattern test. Results  The Running Span Task score proved to be a statistically significant predictor of the listening-in-noise variable. This result showed that the difference in performance between groups G1 and G2 in relation to listening in noise is due not only to aging, but also to changes in working memory. Conclusion  The study showed that working memory is a predictor of listening performance in noise in individuals with normal hearing, and that this task can provide important information for investigation in individuals who have difficulty hearing in unfavorable environments.

引言 在临床实践中,听力损失程度和结构相同的患者,甚至听阈正常的患者,在言语感知方面的表现却大相径庭。出现这种情况的原因可能是,除了听觉灵敏度之外,还有其他因素干扰了言语感知。因此,需要对听者在不利听力条件下的表现进行研究,以确定干扰这些受试者言语感知的过程。目的 验证年龄、时间处理和工作记忆对噪声中语音识别的影响。方法 38 名听阈正常的成年人和老年人参加了研究。参与者分为两组:成人组(G1)10 人,年龄在 21 至 33 岁之间;老年人组(G2)28 人,年龄在 60 至 81 岁之间。他们接受了听力评估,包括葡萄牙语句子列表测试、噪音间隙测试、数字跨度记忆测试、奔跑跨度任务、Corsi 方块敲击测试和视觉模式测试。结果 跑步跨度任务得分被证明对噪声中听力变量有显著的统计学预测作用。这一结果表明,G1 组和 G2 组在噪声中听力方面的表现差异不仅是由于老化,还与工作记忆的变化有关。结论 该研究表明,工作记忆可以预测听力正常的人在噪声中的听力表现,这项任务可以为调查在不利环境中听力有困难的人提供重要信息。
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引用次数: 0
The Effect of Simultaneous Contralateral White Noise Masking on Cortical Auditory Evoked Potentials Elicited by Speech Stimuli. 同时对侧白噪声掩蔽对言语刺激引起的皮层听觉诱发电位的影响
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0043-1767675
Luiza Dandara de Araújo Felix, Pedro Lemos Menezes, Lisiane Vital de Oliveira, Carlos Henrique Alves Batista, Aline Tenório Lins Carnaúba, Kelly Cristina Lira de Andrade

Introduction  Noise obscures speech signal, causing auditory masking. The effects of this masking can be observed through the cortical auditory evoked potentials (CAEPs). White noise, in turn, has an effect on the auditory cortex, interfering, for example, with lexical decision making. Objective  To analyze the effect of simultaneous masking by contralateral white noise on CAEPs elicited by speech stimuli. Methods  Cross-sectional observational analytical study carried out with 15 participants of both sexes, who were submitted to CAEPs in two conditions: 1) without noise; 2) with white noise at 100 dBSPL intensity, contralaterally and simultaneously. To compare these conditions, the Student t test or the Wilcoxon test were used, depending on the sample normality. Differences with p values < 0.05 were considered significant. Results : When white noise was presented contralaterally and simultaneously to the CAEPs with speech stimulus, an increase in P1, N1 and P2 wave latencies was observed. P1 and P2 amplitudes and N1-P2 peak to peak amplitude also increased, unlike N1 amplitude, which decreased. The differences were significant for P1 and P2 wave latencies and for P2 wave amplitude. Conclusion  The simultaneous masking effect was observed from the morphological alterations of the CAEPs with speech stimulus when white noise was presented in the contralateral ear. There was a significant increase in P1 and P2 wave latencies, as well as in P2 wave amplitude.

引言 噪声会掩盖语音信号,造成听觉掩蔽。这种掩蔽的影响可以通过皮层听觉诱发电位(CAEPs)观察到。反过来,白噪声也会对听觉皮层产生影响,例如干扰词汇决策。目的 分析对侧白噪声同时掩蔽对言语刺激引起的 CAEPs 的影响。方法 对 15 名男女参与者进行横断面观察分析研究,他们在两种条件下接受 CAEPs:1) 无噪声;2) 100 dBSPL 强度的白噪声,对侧同时进行。根据样本的正态性,采用学生 t 检验或 Wilcoxon 检验对这两种情况进行比较。P 值小于 0.05 的差异被视为显著差异。结果:当白噪声与语音刺激同时出现在 CAEPs 的对侧时,观察到 P1、N1 和 P2 波潜伏期增加。P1 和 P2 波幅以及 N1-P2 波峰至峰值波幅也有所增加,而 N1 波幅则有所减少。P1 和 P2 波潜伏期和 P2 波振幅的差异显著。结论 当白噪声在对侧耳中出现时,从 CAEPs 的形态学变化中可以观察到语音刺激的同步掩蔽效应。P1 波和 P2 波潜伏期以及 P2 波振幅明显增加。
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引用次数: 0
Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study. 评估全甲状腺切除术后症状性低钙血症的风险:一项前瞻性研究
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.1055/s-0043-1777450
Andro Košec, Ana Gašić, Filip Hergešić, Ivan Rašić, Vesna Košec, Vladimir Bedeković

Introduction  The most common postoperative complication of total thyroidectomy is hypocalcemia, usually monitored using serum parathyroid hormone and calcium values. Objective  To identify the most accurate predictors of hypocalcemia, construct a risk assesment algorithm and analyze the impact of using several calcium correction formulas in practice. Methods  A prospective, single-center, non-randomized longitudinal cohort study on 205 patients undergoing total thyroidectomy. Parathyroid hormone, serum, and ionized calcium were sampled post-surgery, with the presence of symptomatic or laboratory-verified asymptomatic hypocalcemia designated as primary outcome measures. Results  Parathyroid hormone sampled on the first postoperative day was the most sensitive predictor of symptomatic hypocalcemia development (sensitivity 80.22%, cut-off value ≤2.03 pmol/L). A combination of serum calcium and parathyroid concentration sampled on the first postoperative day predicted the development of hypocalcemia during recovery with the highest sensitivity and specificity (94% sensitivity, cut-off ≤2.1 mmol/L, and 89% specificity, cut-off ≤1.55 pmol/L, respectively). The use of algorithms and correction formulas did not improve the accuracy of predicting symptomatic or asymptomatic hypocalcemia. Conclusions  The most sensitive predictor of symptomatic hypocalcemia present on the fifth postoperative day was PTH sampled on the first postoperative day. The need for algorithms and correction formulas is limited.

引言 甲状腺全切除术术后最常见的并发症是低钙血症,通常使用血清甲状旁腺激素和血钙数值进行监测。目的 确定低钙血症最准确的预测因素,构建风险评估算法,并分析在实践中使用多种钙校正公式的影响。方法 对 205 名接受全甲状腺切除术的患者进行前瞻性、单中心、非随机纵向队列研究。手术后对甲状旁腺激素、血清和离子钙进行采样,以是否出现无症状或实验室证实的无症状低钙血症为主要结果指标。结果 术后第一天采样的甲状旁腺激素是预测症状性低钙血症发生的最灵敏指标(灵敏度为80.22%,临界值≤2.03 pmol/L)。术后第一天采样的血清钙和甲状旁腺浓度组合预测恢复期低钙血症的发生具有最高的灵敏度和特异性(灵敏度为94%,临界值≤2.1 mmol/L;特异性为89%,临界值≤1.55 pmol/L)。使用算法和校正公式并不能提高预测无症状或无症状低钙血症的准确性。结论 对术后第五天出现的无症状低钙血症最敏感的预测指标是术后第一天采样的 PTH。对算法和校正公式的需求有限。
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引用次数: 0
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International Archives of Otorhinolaryngology
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