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GATCGGenerator: New Software for Generation of Quasirandom Nucleotide Sequences GATCGGenerator:生成准随机核苷酸序列的新软件
Pub Date : 2023-09-29 DOI: 10.23947/2687-1653-2023-23-3-296-306
O. Yu. Kiryanova, R. R. Garafutdinov, I. M. Gubaydullin, A. V. Chemeris
Introduction . In recent decades, knowledge about DNA has been increasingly used to solve biological problems (calculations using DNA, long-term storage of information). Principally, we are talking about cases when it is required to select artificial nucleotide sequences. Special programs are used to create them. However, existing generators do not take into account the physicochemical properties of DNA and do not allow obtaining sequences with a pronounced “non-biological” structure. In fact, they generate sequences by distributing nucleotides randomly. The objective of this work is to create a generator of quasirandom sequences with a special nucleotide structure. It should take into account some physicochemical features of nucleotide structures, and it will be involved in storing non-biological information in DNA. Materials and Methods . A new GATCGGenerator software for generating quasirandom sequences of nucleotides was described. It was presented as SaaS (from “software as a service”), which provided its availability from various devices and platforms. The program generated sequences of a certain structure taking into account the guanine-cytosine (GC) composition and the content of dinucleotides. The performance of the new program algorithm was presented. The requirements for the generated nucleotide sequences were set using a chat in Telegram, the interaction with the user was clearly shown. The differences between the input parameters and the specific nucleotide structures obtained as a result of the program were determined and generalized. Also, the time costs of generating sequences for different input data were given in comparison. Short sequences differing in type, length, GC composition and dinucleotide content were studied. The tabular form shows how the input and output parameters are correlated in this case. Results . The developed software was compared to existing nucleotide sequence generators. It has been established that the generated sequences differ in structure from the known DNA sequences of living organisms, which means that they can be used as auxiliary or masking oligonucleotides suitable for molecular biological manipulations (e.g., amplification reactions), as well as for storing non-biological information (images, texts, etc.) in DNA molecules. The proposed solution makes it possible to form specific sequences from 20 to 5 000 nucleotides long with a given number of dinucleotides and without homopolymer fragments. More stringent generation conditions remove known limitations and provide the creation of quasirandom sequences of nucleotides according to specified input parameters. In addition to the number and length of sequences, it is possible to determine the GC composition, the content of dinucleotides, and the nature of the nucleic acid (DNA or RNA) in advance. Examples of short sequences differing in length, GC composition and dinucleotide content are given. The obtained 30-nucleotide sequences were tested. The a
介绍。近几十年来,有关DNA的知识越来越多地用于解决生物学问题(利用DNA进行计算,信息的长期存储)。我们主要讨论的是需要选择人工核苷酸序列的情况。使用特殊的程序来创建它们。然而,现有的生成器没有考虑到DNA的物理化学性质,也不允许获得具有明显“非生物”结构的序列。事实上,它们通过随机分布核苷酸来产生序列。这项工作的目的是创建一个具有特殊核苷酸结构的准随机序列发生器。它应该考虑到核苷酸结构的一些物理化学特征,它将涉及在DNA中存储非生物信息。材料与方法。描述了一种新的GATCGGenerator软件,用于生成准随机核苷酸序列。它以SaaS(来自“软件即服务”)的形式出现,提供了它在各种设备和平台上的可用性。该程序生成了考虑鸟嘌呤-胞嘧啶(GC)组成和二核苷酸含量的一定结构的序列。介绍了新程序算法的性能。生成的核苷酸序列的要求使用Telegram中的聊天设置,与用户的交互清晰显示。输入参数和特定核苷酸结构之间的差异作为程序的结果被确定和推广。并对不同输入数据生成序列的时间开销进行了比较。研究了不同类型、长度、GC组成和二核苷酸含量的短序列。表格形式显示了在本例中输入和输出参数是如何关联的。结果。将开发的软件与现有的核苷酸序列生成器进行比较。已经确定生成的序列在结构上不同于生物体的已知DNA序列,这意味着它们可以用作辅助或掩蔽寡核苷酸,适用于分子生物学操作(例如,扩增反应),以及用于存储DNA分子中的非生物信息(图像,文本等)。提出的解决方案可以形成特定的序列从20到5000核苷酸长与给定数量的二核苷酸,没有均聚物片段。更严格的生成条件消除了已知的限制,并根据指定的输入参数提供了核苷酸的准随机序列的创建。除了序列的数量和长度外,还可以提前确定GC组成、二核苷酸的含量以及核酸(DNA或RNA)的性质。给出了长度、GC组成和二核苷酸含量不同的短序列的例子。对得到的30个核苷酸序列进行检测。与已知生物DNA序列无100%同源性。所生成的序列在长度为25个核苷酸时具有最大的符合性(相似性约为80%)。由此证明,GATCGGenerator可以高效生成非生物核苷酸序列。讨论与结论。新的生成器提供了一个给定的GC组成的核苷酸序列的硅创建。该溶液可以排除均聚物碎片,从而从质量上提高序列的物理化学稳定性。
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引用次数: 0
Sensitivity of Diffusion-Weighted Image Combined with T2 Turbo Inversion Recovery Magnitude Sequence and as an Alternative to Contrast-Enhanced MRI in the Detection of Perianal Fistula 弥散加权图像联合T2 Turbo反转恢复数量级序列检测肛周瘘的敏感性及对比增强MRI的替代方法
Pub Date : 2023-09-29 DOI: 10.23947/2687-1653-2023-23-3-307-316
Noor Fadhil Baqir, Rasha Sabeeh Ahmed, Khaleel Ibraheem Mohsen
Introduction . Perianal fistula rapidly develops an abscess, requiring surgical decompression. However, simple cases must be managed. However, for patients with renal insufficiency, MRI with contrast is contraindicated. It is proposed to use diffusion-weighted images that can diagnose anal fistulae, showing areas of high signal intensity (inflammatory tissues). The aim is to determine sensitivity of diffusion-weighted image combined with T2 turbo inversion recovery magnitude and as an alternative technique to contrast-enhanced MRI using clinical examination as a reference. Materials and Methods . Study included fifty patients with a clinical diagnosis of perianal fistula. MRI sequences were T2 turbo inversion recovery magnitude in oblique coronal and axial planes, diffusion-weighted image, and T1 weighted image turbo spin echo (fat suppression) pre- and post-administration of contrast agents in oblique axial planes. Three radiologists evaluated the MR imaging data using a questionnaire of parameters that necessitated a binary response, “yes” or “no” answer. Results. Diffusion-weighted image combined with axial T2 turbo inversion recovery magnitude sequence had 96.7 %. All raters agreed that it is sensitive enough to correctly identify perianal fistula with a moderate Kappa agreement (k = 0.586) and p-value<0.001. The mean value of rater's responses was 76.7 % represents sensitivity of diffusion-weighted images + T2 turbo inversion recovery magnitude as an alternative technique to T1-enhanced contrast with moderate (k = 0.553) agreement between raters and P-value<0.001. Discussion and Conclusion . Diffusion-weighted images and T2 turbo inversion recovery magnitude sequences exhibit comparable efficacy to T1-enhanced contrast sequences in detecting perianal fistula. This may be an option for patients with renal impairment who cannot receive an MRI contrast.
介绍。肛周瘘迅速发展为脓肿,需要手术减压。然而,简单的情况必须加以管理。然而,对于肾功能不全的患者,MRI造影剂是禁忌的。建议使用弥散加权图像诊断肛瘘,显示高信号强度区域(炎症组织)。目的是确定扩散加权图像结合T2涡轮反转恢复幅度的灵敏度,并以临床检查为参考,作为对比增强MRI的替代技术。材料与方法。本研究包括50例临床诊断为肛周瘘的患者。MRI序列为斜冠状面和轴向面T2涡轮反转恢复幅度、扩散加权图像、斜轴向面造影剂前后T1涡轮旋转回波(脂肪抑制)加权图像。三位放射科医生使用一份需要二元回答的参数问卷来评估磁共振成像数据,答案是“是”或“否”。结果。扩散加权图像结合轴向T2涡轮反转恢复幅度序列为96.7%。所有评分者一致认为,该方法足够敏感,能够正确识别肛周瘘,Kappa一致性中等(k = 0.586), p值为0.001。评分者的平均反应值为76.7%,代表了扩散加权图像的敏感性+ T2涡轮反演恢复幅度作为t1增强对比的替代技术,评分者与p值之间的一致性为中等(k = 0.553) <0.001。讨论与结论。弥散加权图像和T2涡轮反转恢复幅度序列在检测肛周瘘方面与t1增强对比序列具有相当的疗效。对于不能接受MRI造影的肾功能损害患者,这可能是一种选择。
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引用次数: 0
Model of a Parallel-Pipeline Computational Process for Solving a System of Grid Equations 求解网格方程组的并行管道计算过程模型
Pub Date : 2023-09-29 DOI: 10.23947/2687-1653-2023-23-3-329-339
V. N. Litvinov, N. B. Rudenko, N. N. Gracheva
Introduction . Environmental problems arising in shallow waters and caused by both natural and man-made factors annually do significant damage to aquatic systems and coastal territories. It is possible to identify these problems in a timely manner, as well as ways to eliminate them, using modern computing systems. But earlier studies have shown that the resources of computing systems using only a central processor are not enough to solve large scientific problems, in particular, to predict major environmental accidents, assess the damage caused by them, and determine the possibilities of their elimination. For these purposes, it is proposed to use models of the computing system and decomposition of the computational domain to develop an algorithm for parallel-pipeline calculations. The research objective was to create a model of a parallel-conveyor computational process for solving a system of grid equations by a modified alternating-triangular iterative method using the decomposition of a three-dimensional uniform computational grid that takes into account technical characteristics of the equipment used for calculations. Materials and Methods . Mathematical models of the computer system and computational grid were developed. The decomposition model of the computational domain was made taking into account the characteristics of a heterogeneous system. A parallel-pipeline method for solving a system of grid equations by a modified alternating-triangular iterative method was proposed. Results. A program was written in the CUDA C language that implemented a parallel-pipeline method for solving a system of grid equations by a modified alternating-triangular iterative method. The experiments performed showed that with an increase in the number of threads, the computation time decreased, and when decomposing the computational grid, it was rational to split into fragments along coordinate z by a value not exceeding 10. The results of the experiments proved the efficiency of the developed parallel-pipeline method. Discussion and Conclusion . As a result of the research, a model of a parallel-pipeline computing process was developed using the example of one of the most time-consuming stages of solving a system of grid equations by a modified alternating-triangular iterative method. Its construction was based on decomposition models of a three-dimensional uniform computational grid, which took into account the technical characteristics of the equipment used in the calculations. This program can provide you for the acceleration of the calculation process and even loading of program flows in time. The conducted numerical experiments validated the mathematical model of decomposition of the computational domain.
介绍。由自然和人为因素引起的浅水环境问题每年都对水生系统和沿海地区造成重大损害。使用现代计算系统,及时发现这些问题以及消除它们的方法是可能的。但早期的研究表明,仅使用中央处理器的计算系统的资源不足以解决大型科学问题,特别是预测重大环境事故,评估它们造成的损害,并确定消除它们的可能性。为此,提出利用计算系统的模型和计算域的分解来开发并行管道计算的算法。研究目标是在考虑到用于计算的设备的技术特性的情况下,利用三维均匀计算网格的分解,采用改进的交替三角形迭代法,建立一个求解网格方程组的平行输送机计算过程模型。材料与方法。建立了计算机系统和计算网格的数学模型。考虑异构系统的特点,建立了计算域的分解模型。提出了一种用改进的交变三角迭代法求解网格方程组的并行管道方法。结果。用CUDA C语言编写了一个程序,实现了用改进的交替三角迭代法求解网格方程组的并行流水线方法。实验表明,随着线程数的增加,计算时间减少,并且在分解计算网格时,沿着坐标z拆分为不超过10的片段是合理的。实验结果证明了该方法的有效性。讨论与结论。在此基础上,以改进的交变三角迭代法求解网格方程组最耗时的一个阶段为例,建立了并行管道计算过程模型。它的构建基于三维均匀计算网格的分解模型,考虑到计算中使用的设备的技术特性。该程序可以为您提供计算过程的加速,甚至程序流的加载时间。数值实验验证了计算域分解的数学模型。
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引用次数: 0
3D Human Motion Capture Method Based on Computer Vision 基于计算机视觉的三维人体运动捕捉方法
Pub Date : 2023-09-29 DOI: 10.23947/2687-1653-2023-23-3-317-328
A. D. Obukhov, D. L. Dedov, E. O. Surkova, I. L. Korobova
Introduction. The analysis of approaches to tracking the human body identified problems when capturing movements in a three-dimensional coordinate system. The prospects of motion capture systems based on computer vision are noted. In existing studies on markerless motion capture systems, positioning is considered only in two-dimensional space. Therefore, the research objective is to increase the accuracy of determining the coordinates of the human body in three-dimensional coordinates through developing a motion capture method based on computer vision and triangulation algorithms. Materials and Methods . A method of motion capture was presented, including calibration of several cameras and formalization of procedures for detecting a person in a frame using a convolutional neural network. Based on the skeletal points obtained from the neural network, a three-dimensional reconstruction of the human body model was carried out using various triangulation algorithms. Results. Experimental studies have been carried out comparing four triangulation algorithms: direct linear transfer, linear least squares method, L2 triangulation, and polynomial methods. The optimal triangulation algorithm (polynomial) was determined, providing an error of no more than 2.5 pixels or 1.67 centimeters. Discussion and Conclusion . The shortcomings of existing motion capture systems were revealed. The proposed method was aimed at improving the accuracy of motion capture in three-dimensional coordinates using computer vision. The results obtained were integrated into the human body positioning software in three-dimensional coordinates for use in virtual simulators, motion capture systems and remote monitoring.
介绍。对跟踪人体的方法的分析发现了在三维坐标系中捕捉运动时存在的问题。展望了基于计算机视觉的运动捕捉系统的发展前景。在现有的无标记动作捕捉系统研究中,定位只考虑二维空间。因此,研究目标是通过开发一种基于计算机视觉和三角测量算法的运动捕捉方法,提高在三维坐标中确定人体坐标的精度。材料与方法。提出了一种运动捕捉方法,包括几个摄像机的校准和使用卷积神经网络检测帧中的人的形式化程序。基于神经网络获取的骨骼点,利用各种三角剖分算法对人体模型进行三维重建。结果。实验研究比较了四种三角剖分算法:直接线性转移、线性最小二乘法、L2三角剖分和多项式方法。确定了最优三角剖分算法(多项式),误差不超过2.5像素(1.67厘米)。讨论与结论。揭示了现有动作捕捉系统的不足。该方法旨在提高计算机视觉在三维坐标下的运动捕捉精度。所获得的结果被集成到三维坐标的人体定位软件中,用于虚拟模拟器、运动捕捉系统和远程监控。
{"title":"3D Human Motion Capture Method Based on Computer Vision","authors":"A. D. Obukhov, D. L. Dedov, E. O. Surkova, I. L. Korobova","doi":"10.23947/2687-1653-2023-23-3-317-328","DOIUrl":"https://doi.org/10.23947/2687-1653-2023-23-3-317-328","url":null,"abstract":"Introduction. The analysis of approaches to tracking the human body identified problems when capturing movements in a three-dimensional coordinate system. The prospects of motion capture systems based on computer vision are noted. In existing studies on markerless motion capture systems, positioning is considered only in two-dimensional space. Therefore, the research objective is to increase the accuracy of determining the coordinates of the human body in three-dimensional coordinates through developing a motion capture method based on computer vision and triangulation algorithms. Materials and Methods . A method of motion capture was presented, including calibration of several cameras and formalization of procedures for detecting a person in a frame using a convolutional neural network. Based on the skeletal points obtained from the neural network, a three-dimensional reconstruction of the human body model was carried out using various triangulation algorithms. Results. Experimental studies have been carried out comparing four triangulation algorithms: direct linear transfer, linear least squares method, L2 triangulation, and polynomial methods. The optimal triangulation algorithm (polynomial) was determined, providing an error of no more than 2.5 pixels or 1.67 centimeters. Discussion and Conclusion . The shortcomings of existing motion capture systems were revealed. The proposed method was aimed at improving the accuracy of motion capture in three-dimensional coordinates using computer vision. The results obtained were integrated into the human body positioning software in three-dimensional coordinates for use in virtual simulators, motion capture systems and remote monitoring.","PeriodicalId":13758,"journal":{"name":"International Journal of Advanced Engineering Research and Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135293400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Dynamic Characteristics of an Automated Position Long-Stroke Pneumatic Actuator of Fabrication System 加工系统自动定位长行程气动执行器动态特性研究
Pub Date : 2023-09-29 DOI: 10.23947/2687-1653-2023-23-3-283-295
D. A. Korotych, V. S. Sidorenko, S. P. Prikhodko
Introduction . Long-stroke movements in automated pneumatic drives account for a significant number of executive movements in coordinate tables, automated warehouses, cutting machines, etc. Long-stroke movements degrade the dynamic quality and positioning of the drive. This is due to the friction of the piston and the nonlinear characteristics of the compressed gas flow in significant volumes of the pressure and drain cavities of the cylinder. Thus, it seems promising to create an automated position pneumatic actuator for long-stroke movements. This will increase the productivity of processes while providing the declared accuracy. The objective of the work is to obtain a mathematical model and dependences of the critical parameters of the proposed automated position long-stroke pneumatic drive of fabrication system in the areas of acceleration, steady-speed movement, deceleration, and braking. Materials and Methods . The basis for calculations and modeling was the scheme of two trajectories of movement from point A to point E, taking into account the forces expended on these processes. The optimal displacement was determined using the Portnyagin’s principle (i.e., optimal performance). Proportional drive control was presented as a method of achieving the result. For long-stroke drive movements, schematic solution and design scheme were visualized in detail (presented as drawings). An original jet sensor with an internal pneumatic connection and a pneumo-mechanic discrete-proportional device for the control loop performance were proposed. The mathematical model included the movement and braking of the piston, the balance of mass flow, the pressure at points, and the control loop. The system of equations was solved by the Runge — Kutta method in the SimInTech software product. Based on the results of the study of a generalized mathematical model, the dependences of changes in the kinematic, power and pneumatic properties of the drive were constructed in real time during a typical positioning cycle. The information was summarized and presented as a set of graphs. Results. The mathematical model was formed according to a set of calculations. It took into account the dependences characteristic of the movement of the piston of the pneumatic cylinder. The balance of mass flow was investigated by the equations of gas flow during compression in the chamber, through distributors and throttles, in the discharge and drain cavities and in the control device. Inequalities describing the pressures at the points and the control loop were considered. A complex mathematical model was solved in the SimInTech software environment by the Runge — Kutta method with a variable integration step. A fragment of the program was selected as one of the illustrations. It showed that the software used the following indicators for calculations: target and reduced coordinates; absolute gas constant; coefficients of spring stiffness, resistance, adiabatic and viscous friction in t
介绍。自动化气动驱动器中的长行程运动占坐标台,自动化仓库,切割机等执行运动的显着数量。长冲程运动降低了驱动器的动态质量和定位。这是由于活塞的摩擦和压缩气体在气缸压力腔和排气腔中大量流动的非线性特性造成的。因此,似乎有希望创建一个自动位置气动执行器的长行程运动。这将提高流程的生产率,同时提供声明的准确性。本文的工作目的是获得制造系统自动位置长行程气动驱动在加速、稳速运动、减速和制动等方面的数学模型和关键参数的依赖关系。材料与方法。计算和建模的基础是从A点到E点的两条运动轨迹方案,考虑到在这些过程中所消耗的力。利用波特尼亚金原理(即最优性能)确定最优位移。提出了比例驱动控制作为实现这一结果的一种方法。对于长行程驱动运动,给出了详细的原理图解和设计方案(以图纸形式呈现)。提出了一种带有内部气动连接的原始射流传感器和用于控制回路性能的气动-力学离散比例装置。数学模型包括活塞的运动和制动、质量流量平衡、各点压力和控制回路。在SimInTech软件产品中采用龙格-库塔法求解方程组。基于广义数学模型的研究结果,实时构建了典型定位周期中驱动机构运动学、动力和气动特性变化的依赖关系。这些信息被总结并以一组图表的形式呈现出来。结果。数学模型是根据一组计算形成的。它考虑了气缸活塞运动的依赖特性。利用压缩过程中气体在腔室、分布器和节流器、排料腔和排料腔以及控制装置中的流动方程研究了质量流的平衡。考虑了描述各点和控制回路压力的不等式。在SimInTech软件环境下,采用变积分步长Runge - Kutta法求解复杂数学模型。程序的一个片段被选为插图之一。它表明该软件使用下列指标进行计算:目标和简化坐标;绝对气体常数;活塞内弹簧刚度系数、阻力系数、绝热摩擦系数和粘性摩擦系数;压缩机的压力;气动执行机构运动部件的质量;外部阻力强度;管道、气缸活塞及制动装置的直径;气缸活塞的行程长度;活塞腔和节流阀面积;管道长度及其内部体积。因此,该程序处理了一组重要的数据,这使得有可能获得有意义和充分的结果。给出了求解模型时所用的块与图的关系。我们讨论的是运动,面积,压力,速度和温度的图形。使用带有程序文本和用于集成的块。由此,得到了制造系统的自动气动驱动的数学模型及其运行基本参数的依赖关系。图形表明,气动执行器的操作机构正确地遵循了所提出的轨迹。讨论与结论。研究结果使我们能够考虑驱动器长行程运动的几个阶段,以确定这些过程的时间框架(从0到0.65秒),以及在这些间隔中记录的气缸架的压力和运动速度的变化。有五个这样的阶段:加速、匀速运动、减速、定位速度运动和制动。进一步的研究将集中在优化系统,以减少持续时间,并在外部影响下保持准确的定位。
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引用次数: 0
Optimization of Geometric Characteristics of Cycloidal Profiles of Gerotor Hydraulic Machines 旋转液压机摆线轮廓几何特性优化
Pub Date : 2023-09-29 DOI: 10.23947/2687-1653-2023-23-3-269-282
S. O. Kireev, A. R. Lebedev, M. V. Korchagina
Introduction . The performance and reliability of gerotor hydraulic machines depend on the geometry of the cycloidal gearing profile. The existing methods of calculating and optimizing the profile parameters are cumbersome, multicriteria and difficult for practical application. Therefore, the problem of creating the methodology for calculating the parameters of the gerotor machine profile suitable for engineering calculations at the stage of conceptual design is a challenge. In this regard, the objective of this work was to modernize the methodology for designing the geometry of the profiles of the end section of hypocycloidal gears used in gerotor hydraulic machines, and to analyze the possibilities of their optimization during preliminary design. In the course of the study, the Mathcad computer mathematics system was used; numerical experiments were carried out to study the influence of geometric profile parameters on the performance and operability of the gerotor hydraulic machine, based on the data obtained and analyzed; recommendations for the design of optimal profiles of the end section of gerotor hydraulic machines were developed. Materials and Methods . Materials included known methods of profile parameters calculation, based on application of classical formulas of hypocycloidal equidistant used for outlining profiles of teeth of working elements of gerotor machines. The basic research method was modeling the gerotor machine profile using Mathcad computer mathematics system. Calculated data were obtained for the selected ranges of varying parameters, processed through the univariate regression analysis. Results. An algorithm for analyzing the tooth profile smoothness was developed. Two target parameters were defined: the cross-sectional area of the end profile, which affects the productivity; the smallest reduced radius of contact that determines operability of the working body. A technique for calculating the target parameters at the early stage of design was proposed. A number of optimal values of profile parameters according to the criteria of productivity and operability of gerotor machine was obtained. The dependences providing the optimum values of profile parameters at the stage of designing were constructed. Discussion and Conclusion . The developed methodology makes it possible to obtain an assessment of the performance and operability of the gerotor hydraulic machine at the design stage of the working body. The research results can be used in mechanical engineering when designing gerotor hydraulic machines in order to improve their technical and operational characteristics.
介绍。转子液压机的性能和可靠性取决于摆线齿轮传动的几何形状。现有的轮廓参数计算和优化方法繁琐,多准则,难以实际应用。因此,在概念设计阶段建立适合工程计算的转子机外形参数的计算方法是一个挑战。在这方面,本工作的目的是现代化的设计方法,用于转子液压机的准摆线齿轮端面轮廓的几何形状,并分析其在初步设计优化的可能性。在研究过程中,使用了Mathcad计算机数学系统;在获得和分析数据的基础上,进行了数值实验,研究了几何轮廓参数对转子液压机性能和可操作性的影响;对旋涡液压机端部截面的优化设计提出了建议。材料与方法。材料包括基于经典准摆线等距公式的已知齿形参数计算方法,该公式用于绘制转子机械工作单元齿形轮廓。本课题的基本研究方法是利用Mathcad计算机数学系统对电机外形进行建模。对选定的各参数取值范围进行计算,并进行单变量回归分析。结果。提出了一种分析齿形平滑度的算法。确定了两个目标参数:影响生产率的端面截面面积;决定工作体的可操作性的最小减小接触半径。提出了一种在设计初期计算目标参数的方法。根据涡旋机的生产率和可操作性标准,得到了一系列的轮廓参数的最优值。建立了在设计阶段提供最优轮廓参数值的依赖关系。讨论与结论。所开发的方法可以在工作体的设计阶段对转子液压机的性能和可操作性进行评估。研究结果可为机械工程中设计转子液压机提供参考,以提高其技术性能和工作性能。
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引用次数: 0
Influence of the Sphero-Cylindrical Tool Orientation Angles on Roughness under Processing Complex-Profile Surfaces 加工复杂曲面时球圆柱刀具取向角对粗糙度的影响
Pub Date : 2023-09-28 DOI: 10.23947/2687-1653-2023-23-3-231-240
M. R. Gimadeev, A. V. Nikitenko, V. O. Berkun
Introduction. When milling complex-profile surfaces of parts, the selection of tool trajectories and orientations affect the roughness parameters. However, in the studies devoted to the formation of trajectories, recommendations to provide the quality of microgeometry of surfaces were not taken into account. Moreover, when writing programs for CNC equipment in CAM systems, the limitations of cutting modes were determined exclusively using a geometric approach. It did not take into account the influence of the orientation angles of the sphero-cylindrical tool relative to the normal plane on the quality of surface treatment, namely on roughness. The work was aimed at the creation of the methodology for selecting the limiting values of the orientation angles of a sphero-cylindrical tool to optimize the process of machining spatially complex surfaces. The tasks included achieving the minimum values of the amplitude roughness parameter Rz and determining the effectiveness of various machining paths. Materials and Methods . Methods of correlation and regression analysis were used, the results were compared and generalized. The least-squares method was applied to estimate the parameters of the regression equation. The DMU 50 ecoline processing center was used for the experimental studies. Roughness was measured on a Surfcam 1800 D profilometer. The material of the samples was steel 12X18N10T. The material of the tool was hard alloy 1620 Sandvik with PVD coating (physical vapor deposition, the closest domestic analogue is T15K6). Results . It has been shown in detail how roughness parameters Rz depend on the angle of inclination and the diameter of the tool. Twenty examples were summarized in a table. Natural regression coefficients were calculated using linear and hyperbolic models. It was found that the diameter of the tool had a greater effect on the formation of roughness parameter Rz than the angle of inclination. For a detailed description of the influence features, the coefficients of multiple, partial, paired correlation and multiple determination were compared. The limitations associated with the angles of inclination of the tool when processing complex surfaces were determined. A scheme for calculating the angle of the normal was visualized, which included the selected step along the axis to determine the lengths of the segments of the broken curve. The profilograms of surfaces obtained with different shaping trajectories were given in the form of drawings. This allowed us to conclude that milling from top to bottom is unsuitable when the tool is tilted 5°– 35°. A map has been compiled by which it is possible to judge the roughness, knowing the type of milling and the inclination angle (from 5° to 80 °). The dependence of the roughness parameter on the processing speed and the use of coolant was represented graphically. The calculated parameters for determining the optimal angle of inclination of the tool were tabulated. Their analysis proved t
介绍。铣削零件复杂轮廓面时,刀具轨迹和方向的选择影响其粗糙度参数。然而,在专门研究轨迹形成的研究中,没有考虑到提供表面微观几何质量的建议。此外,在为CAM系统中的CNC设备编写程序时,切割模式的限制仅使用几何方法确定。它没有考虑球圆柱刀具相对于法线面的取向角对表面处理质量,即粗糙度的影响。该工作旨在创建选择球圆柱刀具取向角极限值的方法,以优化空间复杂曲面的加工过程。任务包括实现振幅粗糙度参数Rz的最小值和确定各种加工路径的有效性。材料与方法。采用相关分析和回归分析的方法,对结果进行比较和归纳。采用最小二乘法估计回归方程的参数。采用DMU 50型生态碱处理中心进行实验研究。粗糙度在Surfcam 1800d轮廓仪上测量。样品的材料为12X18N10T钢。刀具材料为硬质合金1620 Sandvik, PVD涂层(物理气相沉积,国内最接近的类似物是T15K6)。结果。详细说明了粗糙度参数Rz是如何依赖于刀具的倾角和直径的。20个例子总结在一个表格中。采用线性和双曲模型计算自然回归系数。结果表明,刀具直径对粗糙度参数Rz形成的影响大于刀具倾角。通过对多重相关系数、部分相关系数、配对相关系数和多重确定系数的比较,详细描述了影响特征。确定了加工复杂表面时与刀具倾角相关的限制。可视化了一种计算法线角度的方案,其中包括沿轴选择的步骤,以确定破碎曲线的段的长度。以绘图的形式给出了不同成形轨迹下的曲面轮廓图。这使我们得出结论,当刀具倾斜5°- 35°时,从上到下铣削是不合适的。已经编制了一个地图,通过它可以判断粗糙度,知道铣削类型和倾角(从5°到80°)。用图形表示了粗糙度参数与加工速度和冷却剂用量的关系。给出了确定刀具最佳倾角的计算参数。他们的分析证明了所提出的准备控制信息的方法的充分性。讨论与结论。该方法可以在考虑切削速度和最小可能振幅粗糙度参数Rz的情况下确定球圆柱刀具取向角的最佳值。考虑了总角度为5°~ 50°的表面区域进给fz = 0.4 mm/齿的模式。在这种情况下,沿着通过、相反和自下而上方向的轨迹加工,根据参数Rz提供3-6µm范围内的粗糙度。由于参数Rz的显著高度,不建议在最终操作中使用自顶向下的刀具路径。
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引用次数: 0
Study on Dynamic Response Characteristics of Different Asphalt Pavement Structures Based on ALF Test 基于ALF试验的不同沥青路面结构动力响应特性研究
Pub Date : 2023-09-28 DOI: 10.23947/2687-1653-2023-23-3-241-256
Ni Guangcong, A. N. Tiraturyan, E. V. Uglova, A. V. Vorobev
Introduction . In recent years, one of the main trends in the field of testing road structures has become field study of their large-scale models at the accelerated load facility (ALF). It can significantly reduce the cost of selecting the most economical and durable pavement designs. However, the results obtained on the ALF are often relative, since they practically do not correlate with the results of laboratory and field tests on real objects. This study is aimed at a comprehensive investigation of the response of a road structure to a dynamic load, the establishment of patterns of fatigue failure of asphalt concrete layers during the accelerated testing and full-scale tests on real objects. Materials and Methods . During testing, an accelerated load facility was used, located on the territory of the ShanDong Transport University. When conducting field tests, a dynamic loading unit with a falling weight FWD Primax 1500 was used, which recorded the deflection bowl on the surface of the structure under study. To record the dynamic response in the arrangement of the road structure, a complex of strain gauge sensors was used, which made it possible to register both compressive stresses and tensile strains in different layers. The results obtained under natural conditions were compared to the results obtained on the mathematical FEM model. Results. The research results have shown that the thickness of the lower coating layer is the main factor affecting the amount of vertical deformation of the pavement, which must be taken into account at the design stage of the pavement structure. Thus, with a thickness of the upper layer of the base of 10 cm, the vertical deformation was 100 µm, and with a thickness of 20 cm – 55 µm, provided that the overall strength of the structure was ensured. The number of load application cycles on the ALF had a minimal effect on the selected asphalt concrete samples during split tensile tests. Discussion and Conclusion . The adequacy of the results obtained in the course of accelerated testing of road structures was shown through a comprehensive comparison of numerical simulation data and full-scale tests, and the adequacy of the applied calculation methods was validated. The results of the study can be further applied in the road industry to develop and improve the regulatory framework for the design of non-rigid pavement under conditions of increased loads and heavy traffic.
介绍。近年来,道路结构试验领域的主要趋势之一是在加速加载装置(ALF)上进行大型模型的现场研究。它可以显著降低选择最经济和耐用的路面设计的成本。然而,在ALF上获得的结果往往是相对的,因为它们实际上与实验室和实地对真实物体进行测试的结果不相关。本研究旨在全面研究道路结构对动荷载的响应,建立沥青混凝土层在加速试验和实物全尺寸试验中的疲劳破坏模式。材料与方法。在测试期间,使用了一个加速加载设施,位于山东交通大学的领土上。在进行现场试验时,采用了FWD Primax 1500型落重动加载装置,记录了被研究结构表面的挠度碗形。为了记录道路结构布置中的动态响应,使用了一组应变计传感器,这使得记录不同层的压应力和拉应变成为可能。将自然条件下得到的结果与数学有限元模型上得到的结果进行了比较。结果。研究结果表明,下涂覆层厚度是影响路面竖向变形量的主要因素,在路面结构设计阶段必须加以考虑。因此,在保证结构整体强度的前提下,基础上层厚度为10 cm时,竖向变形量为100 μ m,厚度为20 cm - 55 μ m。在劈裂拉伸试验中,ALF上的荷载应用循环次数对所选沥青混凝土样品的影响最小。讨论与结论。通过数值模拟数据与实车试验的综合对比,证明了道路结构加速试验过程中所得结果的充分性,验证了所采用计算方法的充分性。研究结果可以进一步应用于道路行业,以制定和完善在载荷增加和交通繁忙的情况下设计非刚性路面的监管框架。
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引用次数: 0
Buckling of Rectangular Plates under Nonlinear Creep 矩形板在非线性蠕变作用下的屈曲
Pub Date : 2023-09-28 DOI: 10.23947/2687-1653-2023-23-3-257-268
S. B. Yazyev, A. S. Chepurnenko
Introduction. The task of analyzing the stability of plates and shells under creep conditions is critical for structural elements made of materials with the property of aging, which are under the action of long-term loads, since the loss of stability can occur abruptly and long before the exhaustion of the strength resource of the material. Currently, the issues of joint consideration of geometric nonlinearity and creep in the problems of buckling plates remain poorly studied, existing software systems do not provide such calculations. The objective of this work is to develop an algorithm for calculating the stability of rectangular plates with initial deflection, which are subjected to loads in the middle plane, taking into account geometric nonlinearity and creep. Materials and Methods. When obtaining the resolving equations, the geometric and static equations of the theory of flexible elastic plates were taken as the basis. Physical equations were derived from the assumption that total strains were equal to the sum of elastic strains and creep deformations. Finally, the problem was reduced to a system of two differential equations, in which the desired functions were the stress and deflection functions. The resulting system of equations was solved numerically using the finite-difference method in combination with the method of successive approximations and the Euler method. As the boundary conditions for the stress function, the frame analogy was used, as in the case of a plane problem of elasticity theory. Results. The solution to the problem for a plate compressed in one direction by a uniformly distributed load has been presented. The nature of the growth of displacements at different load rates and initial deflection was studied. It has been established that when the vertical displacements reach values comparable to the thickness of the plate, their growth rate begins to decay even at a load greater than the long-term critical one. Discussion and Conclusion . The results of stability analysis using the developed algorithm show that the growth of plate deflection under the considered boundary conditions is limited, stability loss is not observed at any load values not exceeding the instantaneous critical one. This indicates the possibility of long-term safe operation of such structures with a load less than instant critical one.
介绍。分析板壳在蠕变条件下的稳定性是由具有老化特性的材料制成的结构元件在长期载荷作用下的关键任务,因为稳定性的丧失可能在材料强度资源耗尽之前突然发生。目前,屈曲板问题中几何非线性和蠕变的联合考虑问题研究较少,现有的软件系统不提供这样的计算。本工作的目的是开发一种计算具有初始挠度的矩形板的稳定性的算法,考虑几何非线性和蠕变在中间平面上的荷载。材料与方法。在求解方程时,以柔性弹性板理论的几何方程和静力方程为基础。根据总应变等于弹性应变和蠕变变形之和的假设,推导出了物理方程。最后,将该问题简化为两个微分方程组,其中所需函数为应力和挠度函数。利用有限差分法结合逐次逼近法和欧拉法对所得方程组进行了数值求解。与弹性理论的平面问题一样,采用框架类比作为应力函数的边界条件。结果。本文给出了受均布荷载单向压缩的平板问题的求解方法。研究了不同加载速率和初始挠度下的位移增长特性。已经确定,当垂直位移达到与板厚相当的值时,即使在大于长期临界载荷的情况下,其增长率也开始衰减。讨论与结论。利用该算法进行稳定性分析的结果表明,在所考虑的边界条件下,板挠度的增长是有限的,在不超过瞬时临界荷载值的任何荷载值下都没有观察到稳定性损失。这表明这种结构在荷载小于瞬间临界荷载的情况下长期安全运行的可能性。
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引用次数: 0
Implementation of Basic Operations for Sparse Matrices when Solving a Generalized Eigenvalue Problem in the ACELAN-COMPOS Complex 求解ACELAN-COMPOS复合体中广义特征值问题时稀疏矩阵基本运算的实现
Pub Date : 2023-07-14 DOI: 10.23947/2687-1653-2023-23-2-121-129
П.А. Оганесян, О.О. Штейн, P. Oganesyan, Olga Shtein
Introduction. The widespread use of piezoelectric materials in various industries stimulates the study of their physical characteristics and determines the urgency of such research. In this case, modal analysis makes it possible to determine the operating frequency and the coefficient of electromechanical coupling of piezoelectric elements of various devices. These indicators are of serious theoretical and applied interest. The study was aimed at the development of numerical methods for solving the problem of determining resonance frequencies in a system of elastic bodies. To achieve this goal, we needed new approaches to the discretization of the problem based on the finite element method and the execution of the software implementation of the selected method in C# on the .net platform. Current solutions were created in the context of the ACELAN-COMPOS class library. The known methods of solving the generalized eigenvalue problem based on matrix inversion are not applicable to large-dimensional matrices. To overcome this limitation, the presented scientific work implemented the logic of constructing mass matrices and created software interfaces for exchanging data on eigenvalue problems with pre- and postprocessing modules.Materials and Methods. A platform was used to implement numerical methods .net and the C# programming language. Validation of the research results was carried out through comparing the values found with solutions obtained in well-known SAE packages (computer-aided engineering). The created routines were evaluated in terms of performance and applicability for large-scale tasks. Numerical experiments were carried out to validate new algorithms in small-dimensional problems that were solved by known methods in MATLAB. Next, the approach was tested on tasks with a large number of unknowns and taking into account the parallelization of individual operations. To avoid finding the inverse matrix, a modified Lanczos method was programmatically implemented. We examined the formats for storing matrices in RAM: triplets, CSR, СSC, Skyline. To solve a system of linear algebraic equations (SLAE), an iterative symmetric LQ method adapted to these storage formats was used.Results. New calculation modules integrated into the class library of the ACELAN-COMPOS complex were developed. Calculations were carried out to determine the applicability of various formats for storing sparse matrices in RAM and various methods for implementing operations with sparse matrices. The structure of stiffness matrices constructed for the same task, but with different renumbering of nodes of a finite element grid, was graphically visualized. In relation to the problem of the theory of electroelasticity, data on the time required to perform basic operations with stiffness matrices in various storage formats were summarized and presented in the form of a table. It has been established that the renumbering of grid nodes gives a significant increase in performance e
介绍。压电材料在各行各业的广泛应用,激发了对其物理特性的研究,决定了这类研究的紧迫性。在这种情况下,模态分析可以确定各种器件的压电元件的工作频率和机电耦合系数。这些指标具有重要的理论和应用价值。本研究的目的是发展数值方法来解决弹性体系统中共振频率的确定问题。为了实现这一目标,我们需要基于有限元方法的问题离散化的新方法,并在。net平台上用c#执行所选方法的软件实现。当前的解决方案是在ACELAN-COMPOS类库的上下文中创建的。已知的基于矩阵反演的广义特征值问题的求解方法不适用于大维矩阵。为了克服这一限制,提出的科学工作实现了构造质量矩阵的逻辑,并创建了用于与预处理和后处理模块交换特征值问题数据的软件接口。材料与方法。采用。net平台和c#编程语言实现数值方法。通过将研究结果与知名SAE软件包(计算机辅助工程)中得到的解进行比较,验证了研究结果。所创建的例程在性能和大规模任务的适用性方面进行了评估。通过数值实验验证了新算法对MATLAB中已知方法求解的小维问题的有效性。接下来,该方法在具有大量未知数的任务上进行了测试,并考虑了单个操作的并行化。为了避免求逆矩阵,通过编程实现了一种改进的Lanczos方法。我们研究了在RAM中存储矩阵的格式:triplets, CSR, СSC, Skyline。为了求解线性代数方程组(SLAE),采用了一种适用于这些存储格式的迭代对称LQ方法。开发了集成到ACELAN-COMPOS复合体类库中的新的计算模块。通过计算确定了在RAM中存储稀疏矩阵的各种格式的适用性以及使用稀疏矩阵实现操作的各种方法。以图形化的方式可视化了为同一任务构造的刚度矩阵结构,但在有限元网格中节点编号不同。针对电弹性理论的问题,对不同存储格式的刚度矩阵进行基本运算所需时间的数据进行了总结,并以表格的形式提出。已经证明,即使不改变内存中矩阵的内部结构,网格节点的重新编号也能显著提高性能。考虑到研究的目标,已知矩阵存储格式的优点和缺点被命名。因此,当矩阵乘以向量时,CSR是最优的,当矩阵逆时,SKS是最优的。在未知量为103阶的问题中,求解广义特征值问题的迭代方法在速度上获胜。对Lanczos方法的软件实现性能进行了评价。测量了所有操作对总解决时间的贡献。结果表明,求解SLAE的运算时间占算法总时间的95%以上。采用对称LQ法求解SLAE时,矩阵与向量相乘的计算量最大。为了提高算法的性能,采用了共享内存并行化的方法。当使用8个线程时,性能提高了40-50%。讨论与结论。作为科学工作的一部分获得的软件模块在ACELAN-COMPOS包中实现。估计了它们在拟正则有限元网格模型问题上的性能。结合求解电弹性体广义特征值问题得到的刚度矩阵和质量矩阵的结构特点,确定了优选的处理方法。
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International Journal of Advanced Engineering Research and Science
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