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Hypertension best treatment options 2023 高血压最佳治疗方案2023
Pub Date : 2023-07-05 DOI: 10.18203/2349-3933.ijam20232142
Guillermo Avalos Gonzalez, G. Garcia Santiago, J. M. Huerta Velázquez, J. M. Zepeda Torres, Alexa Jimenez Curriel
Systemic arterial hypertension is main cause of cerebrovascular events and coronary disease. Therefore, treatment and control of this disease is of great importance in public health. Arterial hypertension is a common disease that is defined as the persistent elevation of blood pressure more than 130/80 mm HG by the American college of cardiology (ACC)/American heart association (AHA), and by 8th joint national committee (JNC 8) criteria specify≥140/90 mmHg. The treatment of hypertension is based on non-pharmacological strategies and pharmacological. The best treatment for arterial hypertension is the combination of non-pharmacological strategies and pharmacological. We think that the most important step in a plan for primary care providers should be non-pharmacological strategies, principally the change of the diet of the patient, and encouraging them to lose weight and do physical activity daily. In the case of pharmacological strategies, as we saw in different studies and guidelines, all support the use of a combination of different medications. Because this way patients had better responses to treatment and decreased the rate of complications.
全身性动脉高压是脑血管事件和冠状动脉疾病的主要原因。因此,治疗和控制这种疾病对公共卫生具有重要意义。动脉高血压是一种常见疾病,美国心脏病学会(ACC)/美国心脏协会(AHA)将其定义为血压持续升高超过130/80 mmHg,而第8届全国联合委员会(JNC 8)的标准规定血压≥140/90 mmHg。高血压的治疗是基于非药物策略和药物。治疗高血压的最佳方法是药物治疗和非药物治疗相结合。我们认为初级保健提供者计划中最重要的一步应该是非药物策略,主要是改变患者的饮食,并鼓励他们减肥和每天进行体育锻炼。就药理学策略而言,正如我们在不同的研究和指南中看到的,所有的研究和指南都支持使用不同药物的组合。因为这样患者对治疗有更好的反应,减少了并发症的发生率。
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引用次数: 0
Hip fracture treatment and complications after surgery 髋部骨折的治疗及术后并发症
Pub Date : 2023-07-05 DOI: 10.18203/2349-3933.ijam20232143
G. Garcia Santiago, Esteban Torres Magaña, Ana Sofia Ponce Galvez, Aran Alejandro Rodriguez Ceja, Guillermo Avalos Gonzalez
Falls are one of the most important geriatric syndromes due to their high frequency, often without fatal consequences, but they do tend to affect the person's health and quality of life. The purpose of this review is to mention to most used options of treatment and the most common complication that occurred after the treatment. Whether physical or psychological complications. The average age is 82 years in women and 79 years in men; the largest number of causes occur during the day and at home, which is why more than 40% of the population has suffered a previous fracture. Most fractures are the result of trips or falls, but there are 5% who do not report previous traumatic episodes. The most common types of fracture according to the AO/OTA classification correspond to type 31-A1 and 31-A2 which are considered stable, likewise it is mentioned that the scope of treatment commonly used is intramedullary nailing and sliding screw plate, being the second one the preferred one. The risk factors associated with this complication were age, sex, and ASA score. In another way, the surgical complications included hematoma/healing, mechanical disorder, complications, infections, Necrosis, pseudoarthrosis, and malposition Healing and had the same risk factors associated plus the time it took to perform the surgery. 
跌倒是最重要的老年综合征之一,因为它的频率很高,通常没有致命的后果,但它们确实往往会影响人的健康和生活质量。本综述的目的是提及最常用的治疗方案和治疗后最常见的并发症。无论是生理上还是心理上的并发症。女性的平均年龄为82岁,男性为79岁;最多的原因发生在白天和家里,这就是为什么超过40%的人以前都经历过骨折。大多数骨折是绊倒或跌倒造成的,但也有5%的人没有外伤史。根据AO/OTA分类,最常见的骨折类型为31-A1型和31-A2型,被认为是稳定型,同样提到常用的治疗范围是髓内钉和滑动螺钉板,是首选的第二种。与该并发症相关的危险因素有年龄、性别和ASA评分。另一方面,手术并发症包括血肿/愈合、机械紊乱、并发症、感染、坏死、假关节和错位愈合,并且与进行手术所需的时间有相同的风险因素。
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引用次数: 0
Breast ultrasound diagnostic performance and outcomes for mass lesions in Dharma Yadnya general hospital in 2018-2023 2018-2023年达摩雅德亚总医院乳腺超声诊断肿块性病变的表现及结果
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231867
I. Dana, I. N. T. Atmaja
Background: The latest report by the world health organization and international agency for research on cancer told that the incidence and mortality of breast cancer is the most among female cancer patients.Methods: This is descriptive study which uses medical record of 50 samples patients in Dharma Yadnya general hospital. This study include patients  at least 25 years old who presented to the Dharma Yadnya general hospital between January 2019 to March 2023 which get breast ultrasound examination and pathology examination, benign or malignant mass.Results: In ultrasound findings, there are 43 (86%) people with benign cancer, 7 (14%) people with malignant cancer, 43 (86%) people with hipoechoic density and solid lession, 7 (14%) people with isoechoic density and cystic lession, 43 (86%) people with regular margin, 7 (14%) people with irregular margin, 43 (86%) people without lymph nodes axillary, 7 (14%) people with lymph nodes axillary, and by Doppler there are 43 (86%) people without neovascularitation inside lession and 7 (14%) people with neovascularitation inside lession. There are statistically significant relationship (p<0.05) between diagnosis (benign and malignant) with age of patients, density, margin, existence of lymph nodes axillary, and neovascularitation inside the lession by doppler.Conclusions: Breast sonography is the modality of choice for further investigation of palpable breast findings that are not clearly benign and mammographic screen-detected abnormalities.
背景:世界卫生组织和国际癌症研究机构的最新报告表明,乳腺癌的发病率和死亡率是女性癌症患者中最高的。方法:采用描述性研究方法,对达摩雅德雅总医院50例患者的病历资料进行分析。本研究包括2019年1月至2023年3月期间在达摩亚德亚综合医院就诊的至少25岁的患者,他们接受了乳房超声检查和病理检查,良性或恶性肿块。结果:在超声检查中,良性肿瘤43例(86%),恶性肿瘤7例(14%),回声密度及实性病变43例(86%),等回声密度及囊性病变7例(14%),边缘规则43例(86%),边缘不规则7例(14%),无腋窝淋巴结43例(86%),腋窝淋巴结7例(14%),腋窝淋巴结7例(14%)。多普勒检查无血管内病变43例(86%),有血管内病变7例(14%)。多普勒检查与患者年龄、密度、切缘、腋窝有无淋巴结、病变内有无新生血管等因素的良恶性诊断有统计学意义(p<0.05)。结论:乳腺超声检查是进一步调查可触及的乳腺发现的不明显的良性和乳房x线检查发现的异常的首选方式。
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引用次数: 0
Assessment of depression, anxiety and stress among patients with type II diabetes mellitus attending a tertiary care centre 三级医疗中心II型糖尿病患者抑郁、焦虑和压力的评估
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231871
K. Hazarika, M. Ali, Saurabh Agarwal, S. Verma, Vipul Singh
Background: India is home to 17% diabetic (~80 million) population of world and is expected to increase to 135 million by 2045. Chronic illnesses association with psychiatric morbidity. Positive relationship exists between diabetes and psychiatric disorders and have definite negative impact on self-care practices, worsening physical and mental health, diminishing quality of life (QoL) and poor resulting in greater economic burden both to family and society.Method: A cross-sectional study was conducted in a diabetes clinic of a tertiary care facility in North India. Hindi version of DASS 21 was used to ascertain the psychological health of patients which determine the presence of depression, anxiety and stress. Data were analysed using SPSS 20.0Results: We found a high prevalence of depression (49.7%), anxiety (69.7%) and stress (68.3%) among patients belonging to lower socioeconomic status, rural residence and lower literacy rates/illiteracy. The prevalence of depression was higher among females.Conclusions: There is a high prevalence of psychiatric morbidity among the North Indian diabetic population which shows some variability with changing demographic profile.
背景:印度是世界糖尿病人口的17%(约8000万)的家园,预计到2045年将增加到1.35亿。慢性疾病与精神疾病的关系。糖尿病与精神疾病之间存在正相关关系,并对生活自理、身心健康状况恶化、生活质量下降、生活质量差等方面产生负面影响,给家庭和社会带来更大的经济负担。方法:横断面研究是在印度北部三级保健设施的糖尿病诊所进行的。使用印地语版的DASS 21来确定患者的心理健康状况,从而确定是否存在抑郁、焦虑和压力。结果:社会经济地位较低、居住在农村、识字率/文盲率较低的患者中抑郁(49.7%)、焦虑(69.7%)和压力(68.3%)的患病率较高。抑郁症的患病率在女性中较高。结论:在北印度糖尿病人群中,精神疾病发病率较高,但随人口结构的变化而变化。
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引用次数: 0
A rare complication of a relatively common disease: periodic paralysis caused by thyrotoxicosis 一种相对常见的疾病的罕见并发症:甲状腺毒症引起的周期性麻痹
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231880
A. Chanda, Mainak Mandal, S. Sarkar, Nirmalya Roy
Thyrotoxic periodic paralysis is a sporadic form of hypo-kalemic periodic paralysis and it is most commonly presents as sudden onset weakness in the proximal muscles. It is a disorder most commonly seen in Asian men which is characterised by abrupt onset of hypo-kalemia and paralysis and it is primarily affects lower extremities and is secondary to thyrotoxicosis. It is due to an intracellular shift of potassium induced by thyroid hormone sensitisation of Na/K ATPase rather than depletion of total potassium. The absence of a family history, male predilection and, presentation in second to fourth decade of life and signs of thyrotoxicosis and sinus tachycardia help in the diagnosis of the disorder. The age of onset is later and corresponded with age of incidence of thyrotoxicosis. It is very essential to diagnose TPP early and treat appropriately.
甲状腺毒性周期性麻痹是一种散发形式的低钾血症性周期性麻痹,最常见的表现是近端肌肉突然无力。这是一种最常见于亚洲男性的疾病,其特征是突然发作的低钾血症和瘫痪,主要影响下肢,继发于甲状腺毒症。这是由于甲状腺激素致敏Na/K atp酶引起的细胞内钾转移,而不是总钾的消耗。家族史的缺失,男性的偏好,在生命的第二到第四十年的表现和甲状腺毒症和窦性心动过速的迹象有助于疾病的诊断。发病年龄较晚,与甲状腺毒症发病年龄相对应。早期诊断和适当治疗是至关重要的。
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引用次数: 0
Accuracy of leukocyte esterase reagent strip test and platelet indices for early diagnosis of ascitic fluid infection in liver cirrhosis 白细胞酯酶试剂试纸及血小板指标对肝硬化腹水感染早期诊断的准确性
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231868
R. Dutta, M. M. Rahman, Rezaul I. Patwary, Iftekhar Imam, H. I. Ahmad, S. D. Choudhury, I. Datta, T. Bhuiyan
Background: Spontaneous bacterial peritonitis (SBP) is one of the serious complexities in patients with cirrhosis and ascites. 30-50% of death may occur if it not treated properly. The leucocyte esterase reagent (LER) strip test is a special apparatus for prior detection of neutrophils in the ascetic fluid. The aim of the study was to investigate the diagnostic accuracy of the LER strip test and platelet indices in the early detection of SBP in cirrhotic patients.Methods: This cross-sectional study was carried out in the department of gastrointestinal hepatobiliary and pancreatic disorders (GHPD), BIRDEM, Dhaka, Bangladesh, from January 2018 to October 2019. A total of 110 indoor patients of liver cirrhosis with ascites were enrolled after fulfilment of the inclusion and exclusion criteria with adequate history taking and clinical examination.Results: Out of 110 cases, 68 were male and 42 were female, and among them 23 (20.9%) patients had SBP. LER strip test at grade 4 set as a cut-off value which showed sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy was 91.3%, 90.8%, 70%, 97.5%, and 90% respectively. Mean platelet volume (MPV) and platelet distribution width (PDW) were done by complete blood count, where the MPV cut-off value set as 12.5 fl showed sensitivity, specificity, PPV, NPV, and accuracy were 82.6%, 90.8%, 66%, 96.25%, and 88.18% respectively. PDW cut-off value set on 18.10% revealed sensitivity, specificity, PPV, NPV, accuracy was 82.6%, 83.9%, 50%, 95.71% and 79% respectively. ROC curve was plotted to set the cut-off value by examining sensitivity and specificity. Results were considered statistically significant at p<0.05.Conclusions: This study was undertaken to detect LER strip tests that showed significant results in bedside diagnosis of SBP. Apart from this, a significant increase in MPV and PDW was observed in SBP. So, LER strip tests and platelet indices measurement can be economical and reliable appliances for early diagnosis of SBP.
背景:自发性细菌性腹膜炎(SBP)是肝硬化和腹水患者的严重并发症之一。如果治疗不当,可能会造成30-50%的死亡。白细胞酯酶试剂(LER)试纸是一种特殊的仪器预先检测中性粒细胞在禁欲液。本研究的目的是探讨LER试纸和血小板指标在肝硬化患者早期发现收缩压中的诊断准确性。方法:本横断面研究于2018年1月至2019年10月在孟加拉国达卡BIRDEM胃肠肝胆胰疾病科(GHPD)进行。本研究共纳入110例室内肝硬化腹水患者,均符合纳入和排除标准,并有充分的病史和临床检查。结果:110例患者中,男性68例,女性42例,其中有收缩压23例(20.9%)。以4级LER试纸为临界值,敏感性91.3%,特异性90.8%,阳性预测值(PPV) 70%,阴性预测值(NPV) 97.5%,准确率90%。平均血小板体积(MPV)和血小板分布宽度(PDW)由全血细胞计数测定,其中MPV截断值设为12.5 fl,敏感性为82.6%,特异性为90.8%,66%,96.25%,准确性为88.18%。PDW截断值为18.10%时,敏感性为82.6%,特异性为83.9%,PPV为50%,NPV为95.71%,准确率为79%。绘制ROC曲线,通过检测敏感性和特异性设定截止值。p<0.05认为结果有统计学意义。结论:本研究旨在检测在收缩压床边诊断中显示显著结果的LER条试验。除此之外,在收缩压中观察到MPV和PDW的显著增加。因此,LER试纸和血小板指标检测是早期诊断收缩压经济可靠的手段。
{"title":"Accuracy of leukocyte esterase reagent strip test and platelet indices for early diagnosis of ascitic fluid infection in liver cirrhosis","authors":"R. Dutta, M. M. Rahman, Rezaul I. Patwary, Iftekhar Imam, H. I. Ahmad, S. D. Choudhury, I. Datta, T. Bhuiyan","doi":"10.18203/2349-3933.ijam20231868","DOIUrl":"https://doi.org/10.18203/2349-3933.ijam20231868","url":null,"abstract":"Background: Spontaneous bacterial peritonitis (SBP) is one of the serious complexities in patients with cirrhosis and ascites. 30-50% of death may occur if it not treated properly. The leucocyte esterase reagent (LER) strip test is a special apparatus for prior detection of neutrophils in the ascetic fluid. The aim of the study was to investigate the diagnostic accuracy of the LER strip test and platelet indices in the early detection of SBP in cirrhotic patients.\u0000Methods: This cross-sectional study was carried out in the department of gastrointestinal hepatobiliary and pancreatic disorders (GHPD), BIRDEM, Dhaka, Bangladesh, from January 2018 to October 2019. A total of 110 indoor patients of liver cirrhosis with ascites were enrolled after fulfilment of the inclusion and exclusion criteria with adequate history taking and clinical examination.\u0000Results: Out of 110 cases, 68 were male and 42 were female, and among them 23 (20.9%) patients had SBP. LER strip test at grade 4 set as a cut-off value which showed sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy was 91.3%, 90.8%, 70%, 97.5%, and 90% respectively. Mean platelet volume (MPV) and platelet distribution width (PDW) were done by complete blood count, where the MPV cut-off value set as 12.5 fl showed sensitivity, specificity, PPV, NPV, and accuracy were 82.6%, 90.8%, 66%, 96.25%, and 88.18% respectively. PDW cut-off value set on 18.10% revealed sensitivity, specificity, PPV, NPV, accuracy was 82.6%, 83.9%, 50%, 95.71% and 79% respectively. ROC curve was plotted to set the cut-off value by examining sensitivity and specificity. Results were considered statistically significant at p<0.05.\u0000Conclusions: This study was undertaken to detect LER strip tests that showed significant results in bedside diagnosis of SBP. Apart from this, a significant increase in MPV and PDW was observed in SBP. So, LER strip tests and platelet indices measurement can be economical and reliable appliances for early diagnosis of SBP.","PeriodicalId":13827,"journal":{"name":"International Journal of Advances in Medicine","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81719849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal mortality and morbidity amongst antenatal patients with and without COVID-19 infection 感染和未感染COVID-19的产前患者的孕产妇死亡率和发病率
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231873
S. Kharakwal, Anshul Sharma, Prerana Mishra
Background: The aim of our study is to compare the maternal mortality between those who are infected with COVID-19 infection and those who are not. Our study was done at Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, which included 2 groups: group 1- pregnant women with COVID-19 infection, and group 2- pregnant women without COVID-19 infection.Methods: Our study is prospective and comparative study, done over 250 antenatal patients admitted at our centre, with COVID-19 infection status confirmed either by rapid antigen testing, or by reverse transcription polymerase chain reaction (RT-PCR)/TruNaat testing who had signs and symptoms of COVID-19 infection along with those who needed obstetric intervention or had a high-risk pregnancy status.Results: Preterm labor accounted for the maternal complication with a majority in COVID-19 infected maternal group. Maternal mortality did not increase amongst patients affected with COVID-19 infection within our study duration.Conclusions: Maternal mortality thus did not seem to be affected much by the COVID-19 pandemic probably due to the low infectivity and fatality of third wave was low. 
背景:本研究的目的是比较感染COVID-19和未感染COVID-19的孕产妇死亡率。我们的研究在北方邦Jhansi的Maharani Laxmi Bai医学院进行,包括2组:1组-感染COVID-19的孕妇,2组-未感染COVID-19的孕妇。方法:我们的研究是一项前瞻性和比较研究,对250多名在我们中心入院的产前患者进行了研究,这些患者通过快速抗原检测或逆转录聚合酶链反应(RT-PCR)/TruNaat检测确认了COVID-19感染状态,这些患者有COVID-19感染的体征和症状,以及需要产科干预或高危妊娠状态的患者。结果:新型冠状病毒感染产妇组以早产为主。在我们的研究期间,受COVID-19感染的患者的孕产妇死亡率没有增加。结论:本次疫情对孕产妇死亡率影响不大,可能是由于第三波疫情的低传染性和低致死率所致。
{"title":"Maternal mortality and morbidity amongst antenatal patients with and without COVID-19 infection","authors":"S. Kharakwal, Anshul Sharma, Prerana Mishra","doi":"10.18203/2349-3933.ijam20231873","DOIUrl":"https://doi.org/10.18203/2349-3933.ijam20231873","url":null,"abstract":"Background: The aim of our study is to compare the maternal mortality between those who are infected with COVID-19 infection and those who are not. Our study was done at Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, which included 2 groups: group 1- pregnant women with COVID-19 infection, and group 2- pregnant women without COVID-19 infection.\u0000Methods: Our study is prospective and comparative study, done over 250 antenatal patients admitted at our centre, with COVID-19 infection status confirmed either by rapid antigen testing, or by reverse transcription polymerase chain reaction (RT-PCR)/TruNaat testing who had signs and symptoms of COVID-19 infection along with those who needed obstetric intervention or had a high-risk pregnancy status.\u0000Results: Preterm labor accounted for the maternal complication with a majority in COVID-19 infected maternal group. Maternal mortality did not increase amongst patients affected with COVID-19 infection within our study duration.\u0000Conclusions: Maternal mortality thus did not seem to be affected much by the COVID-19 pandemic probably due to the low infectivity and fatality of third wave was low.\u0000 ","PeriodicalId":13827,"journal":{"name":"International Journal of Advances in Medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79559125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of serum ferritin in patients with acute ischemic stroke in tertiary care hospital 三级医院急性缺血性脑卒中患者血清铁蛋白的相关性研究
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231870
Umashankar Ranjan, Kanmani Panneerselvam
Background: Stroke is a major cause of mortality and morbidity globally. Identifying prognostic markers and mortality predictors is essential for successful intervention and treatment of ischemic stroke. The study aims to examine the role of serum ferritin as a prognostic indicator for stroke severity in conjunction with national institute of health stroke scale (NIHSS) and MRS stroke scales. Furthermore, the association of serum ferritin and several associated risk factors for stroke was also studied.Methods: This study conducted was cross-sectional. 143 patients with acute ischemic stroke who attended the general medicine OPD within 24 hours of admission after the onset of stroke were taken into consideration. Only those patients who matched the inclusion and exclusion criteria were taken for analysis. Acute ischemic stroke patients were admitted with verbal consent, medical background, routine blood, neurological examination, and CT scan, NIHSS scoring, treatment protocols, anti-edema measures, and modified Rankin scale for functional recovery after four weeks.Results: In the present study, 80% were males, and 20% were females. Most study participants were 51-60 years (38%). The mean age is 58.87 years, and the standard deviation is 11.41. About 35% were smokers, 38% were alcoholics, 56% were diabetic, 68% were hypertensives, and 35% had lipid disorders. There is a statistically significant correlation between serum ferritin and the severity of stroke based on the NIHSS scale and the Modified Rankin scale.Conclusions: The study demonstrates the use of serum ferritin as an indicative marker for prognosis patients having an acute ischemic stroke. However, monitoring during follow-up did not show any benefit. The current study glorifies the simplistic use of a serum marker.
背景:中风是全球死亡和发病的主要原因。确定预后标志物和死亡率预测因子对于成功干预和治疗缺血性卒中至关重要。本研究旨在结合美国国立卫生研究院卒中量表(NIHSS)和MRS卒中量表,检验血清铁蛋白作为卒中严重程度的预后指标的作用。此外,还研究了血清铁蛋白与中风相关危险因素的关系。方法:本研究采用横断面法。143例急性缺血性脑卒中患者在卒中发病后24小时内到普通内科门诊就诊。只选取符合纳入和排除标准的患者进行分析。急性缺血性脑卒中患者入院时需口头同意、医学背景、血常规、神经系统检查、CT扫描、NIHSS评分、治疗方案、抗水肿措施、4周后功能恢复的改良Rankin量表。结果:本研究中男性占80%,女性占20%。大多数研究参与者年龄在51-60岁之间(38%)。平均年龄58.87岁,标准差为11.41。约35%为吸烟者,38%为酗酒者,56%为糖尿病患者,68%为高血压患者,35%为脂质紊乱患者。根据NIHSS量表和修正Rankin量表,血清铁蛋白与脑卒中严重程度的相关性有统计学意义。结论:该研究表明血清铁蛋白可作为急性缺血性脑卒中患者预后的指示性指标。然而,随访期间的监测并未显示出任何益处。目前的研究美化了简单使用血清标记物。
{"title":"Association of serum ferritin in patients with acute ischemic stroke in tertiary care hospital","authors":"Umashankar Ranjan, Kanmani Panneerselvam","doi":"10.18203/2349-3933.ijam20231870","DOIUrl":"https://doi.org/10.18203/2349-3933.ijam20231870","url":null,"abstract":"Background: Stroke is a major cause of mortality and morbidity globally. Identifying prognostic markers and mortality predictors is essential for successful intervention and treatment of ischemic stroke. The study aims to examine the role of serum ferritin as a prognostic indicator for stroke severity in conjunction with national institute of health stroke scale (NIHSS) and MRS stroke scales. Furthermore, the association of serum ferritin and several associated risk factors for stroke was also studied.\u0000Methods: This study conducted was cross-sectional. 143 patients with acute ischemic stroke who attended the general medicine OPD within 24 hours of admission after the onset of stroke were taken into consideration. Only those patients who matched the inclusion and exclusion criteria were taken for analysis. Acute ischemic stroke patients were admitted with verbal consent, medical background, routine blood, neurological examination, and CT scan, NIHSS scoring, treatment protocols, anti-edema measures, and modified Rankin scale for functional recovery after four weeks.\u0000Results: In the present study, 80% were males, and 20% were females. Most study participants were 51-60 years (38%). The mean age is 58.87 years, and the standard deviation is 11.41. About 35% were smokers, 38% were alcoholics, 56% were diabetic, 68% were hypertensives, and 35% had lipid disorders. There is a statistically significant correlation between serum ferritin and the severity of stroke based on the NIHSS scale and the Modified Rankin scale.\u0000Conclusions: The study demonstrates the use of serum ferritin as an indicative marker for prognosis patients having an acute ischemic stroke. However, monitoring during follow-up did not show any benefit. The current study glorifies the simplistic use of a serum marker.","PeriodicalId":13827,"journal":{"name":"International Journal of Advances in Medicine","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76665518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of placental laterality with pre-eclampsia 胎盘侧位与先兆子痫的关系
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231874
Fiza Amin, R. Ara, T. Tali
Background: The aim of this study was to observe association between placental laterality and pre-eclampsia in pregnant women.Methods: In this retrospective study, hospital records of 300 pregnant patients who were admitted in our hospital with mild or severe pre-eclampsia between January 2019 to February 2021 were analysed.Results: Ultrasonography performed on these pregnant women between 18 and 24 weeks revealed that 177 (59%) had a lateral placenta and 123 (41%), a central placenta, indicating that pre-eclampsia occurred more frequently in patients with a lateral placental position. Also, pre-eclampsia occurred more frequently in primigravida (first-time moms) than in multigravida (second or subsequent pregnancies), with 132 (44%) primigravida, 106 (35%) second gravida and 62 (21%) multigravidas.Conclusions: This study revealed that the majority of pre-eclampsia patients had placentas that were positioned laterally, indicating a correlation between the two.
背景:本研究的目的是观察孕妇胎盘偏侧与先兆子痫之间的关系。方法:回顾性分析2019年1月至2021年2月我院收治的300例轻、重度先兆子痫孕妇的住院记录。结果:18 ~ 24周的孕妇超声检查显示,177例(59%)为外侧胎盘,123例(41%)为中心胎盘,提示胎盘外侧位置的患者更容易发生先兆子痫。此外,先兆子痫在初产妇(第一次怀孕)中比在多次妊娠(第二次或以后怀孕)中发生的频率更高,初产妇132例(44%),二次妊娠106例(35%),多次妊娠62例(21%)。结论:本研究显示,大多数先兆子痫患者的胎盘位于外侧,表明两者之间存在相关性。
{"title":"Association of placental laterality with pre-eclampsia","authors":"Fiza Amin, R. Ara, T. Tali","doi":"10.18203/2349-3933.ijam20231874","DOIUrl":"https://doi.org/10.18203/2349-3933.ijam20231874","url":null,"abstract":"Background: The aim of this study was to observe association between placental laterality and pre-eclampsia in pregnant women.\u0000Methods: In this retrospective study, hospital records of 300 pregnant patients who were admitted in our hospital with mild or severe pre-eclampsia between January 2019 to February 2021 were analysed.\u0000Results: Ultrasonography performed on these pregnant women between 18 and 24 weeks revealed that 177 (59%) had a lateral placenta and 123 (41%), a central placenta, indicating that pre-eclampsia occurred more frequently in patients with a lateral placental position. Also, pre-eclampsia occurred more frequently in primigravida (first-time moms) than in multigravida (second or subsequent pregnancies), with 132 (44%) primigravida, 106 (35%) second gravida and 62 (21%) multigravidas.\u0000Conclusions: This study revealed that the majority of pre-eclampsia patients had placentas that were positioned laterally, indicating a correlation between the two.","PeriodicalId":13827,"journal":{"name":"International Journal of Advances in Medicine","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83134043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of anemia in non-luminal solid tumors 非腔内实体瘤贫血的研究
Pub Date : 2023-06-27 DOI: 10.18203/2349-3933.ijam20231878
Nupoor Dandavate, Nitin Gadkari, A. Rajbhoj, M. Patil, Naineesh Gaikwad, Ashwini Bankar
Background: Anemia is particularly prevalent in India due to widespread malnutrition. Cancer related anemia affects about three-fourths of cancer patients, causing symptoms like fatigue, appetite loss, and difficulty concentrating, and can worsen cancer prognosis, lengthen treatment, and reduce survival rates. Anemia is a significant cause of tumor hypoxia, which exacerbates the side effects of radiotherapy and chemotherapy, and affects energy levels and emotional distress.Methods: The present cross-sectional study aims to assess the prevalence and types of anemia in patients with newly diagnosed non-luminal solid tumors. The study sample included all patients meeting the inclusion criteria, with a sample size of 100. Clinical evaluation and investigations were carried out to determine the presence and severity of anemia. Data was compiled and analyzed.Results: Of the 100 patients enrolled, 68% had evidence of anemia, and the majority of them were in the age group of 51-60 years. Anemia’s association with body mass index (BMI) was noted and was more common in underweight and normal-weight patients. The commonest malignancies in the study were head and neck cancers, breast cancers and female genital cancers, and the incidence of anemia in these malignancies was higher than in other tumors. When sub-classified a higher prevalence in gynecological tumors was noted. The majority of anemic patients had mild anemia, with microcytic hypochromic anemia being the most common type.Conclusions: The study provides valuable information on the incidence and severity of anemia in patients with non-luminal solid tumors, which can help clinicians in their treatment planning and management.
背景:由于普遍的营养不良,贫血在印度尤为普遍。癌症相关性贫血影响了大约四分之三的癌症患者,导致疲劳、食欲不振和注意力难以集中等症状,并可能恶化癌症预后,延长治疗时间,降低生存率。贫血是肿瘤缺氧的重要原因,它加剧了放疗和化疗的副作用,并影响能量水平和情绪困扰。方法:本横断面研究旨在评估新诊断的非腔内实体瘤患者贫血的患病率和类型。研究样本包括所有符合纳入标准的患者,样本量为100例。进行临床评估和调查,以确定贫血的存在和严重程度。对数据进行了汇编和分析。结果:在纳入的100例患者中,68%的患者有贫血的证据,大多数患者年龄在51-60岁之间。贫血与身体质量指数(BMI)相关,在体重不足和体重正常的患者中更为常见。研究中最常见的恶性肿瘤是头颈癌、乳腺癌和女性生殖器癌,这些恶性肿瘤中贫血的发生率高于其他肿瘤。当细分时,注意到妇科肿瘤的患病率较高。大多数贫血患者为轻度贫血,以小细胞性低色素贫血为最常见的类型。结论:本研究为非腔内实体瘤患者贫血的发生率和严重程度提供了有价值的信息,可帮助临床医生制定治疗计划和管理。
{"title":"Study of anemia in non-luminal solid tumors","authors":"Nupoor Dandavate, Nitin Gadkari, A. Rajbhoj, M. Patil, Naineesh Gaikwad, Ashwini Bankar","doi":"10.18203/2349-3933.ijam20231878","DOIUrl":"https://doi.org/10.18203/2349-3933.ijam20231878","url":null,"abstract":"Background: Anemia is particularly prevalent in India due to widespread malnutrition. Cancer related anemia affects about three-fourths of cancer patients, causing symptoms like fatigue, appetite loss, and difficulty concentrating, and can worsen cancer prognosis, lengthen treatment, and reduce survival rates. Anemia is a significant cause of tumor hypoxia, which exacerbates the side effects of radiotherapy and chemotherapy, and affects energy levels and emotional distress.\u0000Methods: The present cross-sectional study aims to assess the prevalence and types of anemia in patients with newly diagnosed non-luminal solid tumors. The study sample included all patients meeting the inclusion criteria, with a sample size of 100. Clinical evaluation and investigations were carried out to determine the presence and severity of anemia. Data was compiled and analyzed.\u0000Results: Of the 100 patients enrolled, 68% had evidence of anemia, and the majority of them were in the age group of 51-60 years. Anemia’s association with body mass index (BMI) was noted and was more common in underweight and normal-weight patients. The commonest malignancies in the study were head and neck cancers, breast cancers and female genital cancers, and the incidence of anemia in these malignancies was higher than in other tumors. When sub-classified a higher prevalence in gynecological tumors was noted. The majority of anemic patients had mild anemia, with microcytic hypochromic anemia being the most common type.\u0000Conclusions: The study provides valuable information on the incidence and severity of anemia in patients with non-luminal solid tumors, which can help clinicians in their treatment planning and management.","PeriodicalId":13827,"journal":{"name":"International Journal of Advances in Medicine","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88105390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Advances in Medicine
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