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Efficacy of Butanolic Fraction of Cocos Nucifera's Root Aqueous Extract on Induced Anemia Treatment 椰子根水提物丁醇醇部分对诱导性贫血的治疗作用
Pub Date : 2021-11-18 DOI: 10.5539/ijb.v13n2p49
Tchogou Ap, S. M, A. F., Lokonon Je, Medoatinsa Se, Agbangnan Dossa CP, Loko F, A. A., S. A
Cocos nucifera was a coastal plant whose roots were used in pharmacopoeia to treat anemia in Benin. The aqueous extract from its roots stimulated the synthesis of hemoglobin. The aim of this work was to test in vivo the efficacy of the butanolic fraction of the extract in the treatment of anemia. Methods: Wistar rats were anemic with phenylhydrazine for two days. From D2 to D15, some were treated by gavage with the butanolic fraction of the aqueous extract of Cocos nucifera roots at the dose of 40 mg or 60 mg / kg of body weight / day, others were treated with vitafer (an anti-anemic drug) or with distilled water. The rats blood were collected on days D0, D2, D7, D10 and D15 for the complete blood count and the osmotic resistance of the red blood cells. Results: On D2, phenylhydrazine significantly lowered the hemoglobin level and the number of red blood cells, which were respectively corrected on D10 and D15 by the fraction of extract with release of hypochromic macrocytes. However, the effect was slower than that of the crude extract, was not specific to erythropoiesis because it also stimulated thrombopoiesis and was not dose-dependent. Conclusion: The butanolic fraction of the aqueous extract of Cocos nucifera roots corrected anemia by stimulation of hematopoiesis. The observed biological activity would probably be linked to anthocyanins which are mainly isolated by butanol. These results contribute to a better knowledge of bioactive compounds of our antianemic plants.
椰子树是一种沿海植物,其根在贝宁药典中用于治疗贫血。其根部的水提取物刺激了血红蛋白的合成。这项工作的目的是在体内测试提取物的丁醇部分在治疗贫血的功效。方法:用苯肼致Wistar大鼠贫血2 d。从D2到D15,一部分小鼠以40 mg或60 mg / kg体重/天的剂量灌胃椰子根水提物丁醇组分,另一部分小鼠以维生素(一种抗贫血药物)或蒸馏水处理。于D0、D2、D7、D10、D15 d采集大鼠血液,测定全血细胞计数和红细胞渗透阻力。结果:在D2时,苯肼显著降低血红蛋白水平和红细胞数量,在D10和D15时,分别用低色巨细胞释放提取物的组分加以纠正。然而,效果比粗提物慢,对红细胞生成没有特异性,因为它也刺激了血小板生成,并且不具有剂量依赖性。结论:椰子根水提物丁醇组分具有促进造血的作用。所观察到的生物活性可能与主要由丁醇分离的花青素有关。这些结果有助于更好地了解我们的抗贫血植物的生物活性化合物。
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引用次数: 0
Soil Infiltration Management on Perspective of Sustainable Development Goals (SDGs) 可持续发展目标视角下的土壤入渗管理
Pub Date : 2021-06-04 DOI: 10.46300/91011.2021.15.25
H. Susanto, E. Sukoharsono, Bambang Hendroyono, A. Leksono
UB Forest is a Forest Area with Special Purpose (KHDTK) located on the slopes of Mount Arjuno. Before being managed by the University of Brawijaya, there was a change in land cover from natural forest to pine and mahogany production forest. This change was a result of the PHBM (Collaborative Forest Management) contract agreement between Perhutani and the community to carry out agricultural management. The input of organic matter with different quality and quantity will affect the organic matter content and in turn will affect the physical properties of the soil such as bulk density, density and soil porosity. Soil porosity is a physical property of soil that affects soil infiltration. The objective of this study is to identify and analyze the management of Forest Areas and to build a green economy model in the management of KHDTK University of Brawijaya Forest in the Perspective of Sustainable Development Goals (SDGs) in Malang Regency. The method used in this research is qualitative research. Implementation of green economy model in the management of KHDTK University of Brawijaya Forest in the concept of forestry sector contribution related to climate change; the concept of sustainable forest resource management; and the concept of environmental service providers. The results of the infiltration measurement using the single ring infiltrometer method can better describe the infiltration that occurs in the soil. The highest soil infiltration is in protected areas with a soil infiltration rate of 131.33 cm/hour (single ring infiltrometer). Meanwhile, the lowest infiltration was found in the pine production forest plot overlaid with seasonal crops with a soil infiltration rate of 12 cm/hour (single ring infiltrometer).
UB森林是一个特殊用途林区(KHDTK),位于阿尔朱诺山的斜坡上。在由布拉维贾亚大学管理之前,土地覆盖从天然林转变为松木和红木生产林。这一变化是Perhutani与社区之间签订PHBM(合作森林管理)合同协议的结果,该协议旨在开展农业管理。不同质量和数量的有机质的输入会影响有机质含量,进而影响土壤的容重、密度和土壤孔隙度等物理性质。土壤孔隙度是影响土壤入渗的土壤物理性质。本研究的目的是识别和分析森林区域的管理,并在可持续发展目标(SDGs)的视角下建立一个绿色经济模式,以管理玛琅县的KHDTK大学布拉维贾亚森林。本研究采用的方法是定性研究。基于林业部门对气候变化贡献的理念,在布拉维贾亚KHDTK大学森林管理中实施绿色经济模式可持续森林资源管理理念;以及环境服务提供者的概念。单环入渗仪入渗测量结果能较好地描述土壤中发生的入渗情况。土壤入渗速率以保护区最高,为131.33 cm/h(单环入渗计)。覆盖季作物的松林样地入渗率最低,土壤入渗速率为12 cm/h(单环入渗计)。
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引用次数: 1
Predictive Analytics on Academic Performance in Higher Education Institution during COVID-19 using Regression Model 基于回归模型的新型冠状病毒肺炎期间高校学习成绩预测分析
Pub Date : 2021-05-25 DOI: 10.46300/91011.2021.15.21
M. Zulfikri, S. M. Shaharudin, N. A. Rajak, M. S. Ibrahim
- The coronavirus disease 2019 (COVID-19) outbreak in December 2019 had affected the way of living for people around the world including students in educational institutions. These students had to prepare for the continuity of their study mentally and physically by adapting to the online teaching and learning approach, which can significantly impact their academic performance. Hence, this study examines the students’ academic performance on the online teaching and learning approach, thus predicting their academic performance for the upcoming semester. This study enables various actions to be taken in improving and maintaining the student’s performance in their study activities. The study was conducted on undergraduate students from the Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris. This paper presents the prediction of the student’s academic performance with a linear regression model. Evidently, the result shows that the student’s academic performance continually improves while adapting to the online teaching and learning approach. It also shows that there were few respondents affected while adapting to this new norm approach. Hence, the future development of the regression model can be improved by having a more comprehensive range of Malaysian universities’ data. © 2021 North Atlantic University Union NAUN. All rights reserved.
——2019年12月爆发的2019冠状病毒病(COVID-19)影响了包括教育机构学生在内的世界各地人们的生活方式。这些学生必须通过适应在线教学和学习方法,为学习的连续性做好心理和身体上的准备,这对他们的学习成绩会产生重大影响。因此,本研究考察了学生在网络教学方式下的学习成绩,从而预测他们在即将到来的学期的学习成绩。这项研究可以采取各种措施来提高和保持学生在学习活动中的表现。这项研究是在Pendidikan Sultan Idris大学科学与数学学院的本科生中进行的。本文提出了用线性回归模型预测学生学业成绩的方法。结果表明,在适应网络教学方式的过程中,学生的学习成绩不断提高。它还表明,在适应这种新规范方法的过程中,很少有受访者受到影响。因此,通过拥有更全面的马来西亚大学数据,可以改善回归模型的未来发展。©2021北大西洋大学联盟。版权所有。
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引用次数: 4
Sustainable Natural Resources and Environmental Management Systems: Approach of Green Leadership Model 可持续的自然资源和环境管理系统:绿色领导模式的方法
Pub Date : 2021-05-17 DOI: 10.46300/91011.2021.15.18
Normalin Normalin, M. Hatta, Hafizianoor Hafizianoor, H. Hamdani
The research method is qualitative with a theory research action combination with phenomenological approach. The research design using multi-site involving six locus in South Kalimantan, Indonesia. Data collection techniques used were content analysis, participatory observation and depth interviews. The analysis used in answering this research is a combination of various analytical methods to answer each of the objectives namely miles & Huberman analysis, BAPenas MAPP Analysis, Siagian Leadership Role Analysis and Webbed Spider Model Analysis as the ultimate in formulating green leadership models in the management of natural resources and sustainable environment. This study aims to observe, study and find events related to the focus of research to get the formulation of a model of green leadership in the management of natural resources and the sustainable environment that appears naturally. The results of this research found that the Green Leadership Model’s has the criteria : has an understanding of environmental issues, response to policies, community accessibility, institutional support, commitment to environmental sustainability, has innovation that is pro to the environment and an optimal role for leaders in the management of natural resources and sustainable environment. These included the following; in the past experience, sustainable management of natural resources and the environment around the Meratus mountains is strongly influenced by the leadership role both formally and informally. Sustainability of natural resource management and sustainable environment is strongly influenced by leadership who: has awareness and love for the environment, provide motivation through direct implementation to the community through policies that are implemented in maintaining environmental sustainability, provide broad access for the community to participate in the management of natural resources and the environment which experiences a lot of quality degradation ; firm and able to refuse in responding to the demands of the business world which focus on increasing profits alone to exploit natural resources and the environment; and has criteria as an environmentally friendly leadership model in accordance with the criteria needed as an ideal description of leadership. Green leadership models in the management of natural resources and the environment come from formal and informal leadership. The formal green leadership comes from the Regional / Institution / Institution of government, while the informal green leadership comes from the customary leadership that carries out customary rules that do not conflict with government regulations in the management of natural resources and the sustainable environment.
研究方法是定性的、理论研究与现象学研究相结合的研究方法。研究设计采用多地点,涉及印度尼西亚南加里曼丹的六个地点。使用的数据收集技术为内容分析、参与式观察和深度访谈。在回答本研究中使用的分析是各种分析方法的组合,以回答每个目标,即miles & Huberman分析,BAPenas MAPP分析,Siagian领导角色分析和Webbed Spider模型分析,作为制定自然资源和可持续环境管理中的绿色领导模型的最终目标。本研究旨在观察、研究和发现与研究重点相关的事件,从而得出自然资源和自然出现的可持续环境管理中的绿色领导模式。研究结果发现,绿色领导模式具有以下标准:对环境问题的理解、对政策的响应、社区可及性、机构支持、对环境可持续性的承诺、对环境有利的创新以及领导者在自然资源和可持续环境管理中的最佳角色。这些包括:根据过去的经验,Meratus山脉周围自然资源和环境的可持续管理受到正式和非正式领导作用的强烈影响。自然资源管理和可持续环境的可持续性受到领导层的强烈影响,他们对环境有认识和热爱,通过直接实施社区提供动力,通过实施政策来保持环境的可持续性,为社区提供广泛的机会参与自然资源和环境的管理经历了很多质量下降;坚定并能够拒绝商业世界的要求,这些要求只关注增加利润,开发自然资源和环境;并有一个标准,作为一个环保的领导模式,按照标准需要作为一个理想的领导描述。自然资源和环境管理中的绿色领导模式来源于正式领导和非正式领导。正式的绿色领导来自于政府的区域/机构/机构,而非正式的绿色领导来自于在自然资源和可持续环境的管理中执行与政府法规不冲突的习惯规则的习惯领导。
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引用次数: 2
Composition And Diversity Of Plant Species In The Two Types Of Land Cover Of Natural Laboratory Of Hampangen Educational Forest 汉普根教育林自然实验室两种土地覆盖类型中植物物种组成及多样性
Pub Date : 2021-05-14 DOI: 10.46300/91011.2021.15.16
Sosilawaty Sosilawaty, B. Hastari, Ricardo Siregar
Forests are natural resources that contribute to sustaining life support systems. The purpose of this study was to determine the composition and diversity of plant species in the Hampangen Educational Forest Nature Laboratory with the object of research on plant species diversity at growth rates of seedlings, poles, saplings, and trees in the observation plots of secondary swamp forest and swamp scrub. The research was conducted using a combination technique of paths and checkered lines in each of the 30 measurement plots in the two types of observation land. The results showed 52 types of plants found in all types of research land—a total of 42 species in secondary swamp forest and 26 species in scrublands. The types of plants that occupy the highest IVI at all growth levels are Akasia, Jambu-jambu, and Meranti. The Diversity Index of plant species in the study area on both land types was classified as moderate, namely in the range 1,871 - 2,968. The evenness index value (E) of plants in the land cover type of secondary swamp forest and swamp scrub was classified as high in the range of 0.753 - 0.849. The Species Richness Index (R) value of the secondary swamp forest land cover type is classified as high, whereas the swamp scrub land cover type is classified as low, while the average species similarity index in the two land cover types is low.
森林是有助于维持生命支持系统的自然资源。本研究的目的是确定汉普根教育森林自然实验室的植物物种组成和多样性,研究次生沼泽林和沼泽灌丛观测样地幼苗、杆、树苗和乔木生长速率下的植物物种多样性。在两类观测地的30个测量样地中,采用路径与方格线相结合的方法进行研究。结果表明,在所有类型的研究土地上发现了52种植物,其中次生沼泽林有42种,灌丛有26种。在所有生长水平上占据最高IVI的植物类型是Akasia, Jambu-jambu和Meranti。研究区两种土地类型的植物物种多样性指数均为中等,介于1871 ~ 2968之间。次生沼泽林和沼泽灌丛土地覆被类型植物的均匀度指数(E)在0.753 ~ 0.849之间,属于高水平。次级沼泽森林土地覆盖类型的物种丰富度指数(R)值较高,沼泽灌丛土地覆盖类型的物种丰富度指数(R)值较低,而两种土地覆盖类型的平均物种相似度指数较低。
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引用次数: 0
Enhancing Quality of Experience in Malay Language Dyslexia Screening Test 提高马来语阅读障碍筛选测试经验的质素
Pub Date : 2021-05-13 DOI: 10.46300/91011.2021.15.13
Muhammad Hanif Jofri, Mohd. Norasri Ismail, M. F. M. Fudzee
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引用次数: 0
Forest and Land Fire Prevention and Management: Damage Environmental of Central Kalimantan, Indonesia 森林与土地防火与管理:印尼加里曼丹中部的环境损害
Pub Date : 2021-04-22 DOI: 10.46300/91011.2021.15.11
Muhamad Wahyudie, Ferdinan, Salampak, N. Yulianti
The purpose of this study is to analyze policies on the prevention and handling of forest and land fires in Central Kalimantan Province and analyze the factors that influence the prevention and handling of forest and land fires in Central Kalimantan Province. The study used qualitative research methods, with research informants consisting of the Governor, the Head of the Forest Service, the Head of the Environmental Service, Community Leaders, and the people of Central Kalimantan Province. The data collection technique is done by observation, interview, and documentation study. At the same time, the data analysis used is an interactive model analysis consisting of data condensation, data display, and drawing conclusions/verification. The results showed that in accordance with Regional Regulation No. 5 of 2003 and Governor's Regulation No. 24 of 2017, the policy of preventing and handling forest and land fires in Central Kalimantan Province was carried out in two stages, namely the prevention policy and the policy of handling forest and land fires. However, in its implementation, it prioritizes the policy to extinguish forest and land fires because it has more economic, social, educational, and health impacts. Efforts to prevent and handle forest and land fires in Central Kalimantan Province are constrained by inadequate human resources, limited budget, and lack of facilities and infrastructure. KeywordsPolicy Analysis, Prevention, Handling, Fire, Environmental Forest and Land
本研究的目的是分析加里曼丹省中部森林和土地火灾的预防和处理政策,分析影响加里曼丹省中部森林和土地火灾的预防和处理的因素。该研究采用定性研究方法,研究人员包括省长、林务局局长、环境局局长、社区领袖和中加里曼丹省人民。数据收集技术采用观察法、访谈法和文献研究法。同时,使用的数据分析是由数据浓缩、数据显示、得出结论/验证组成的交互式模型分析。结果表明,根据2003年第5号区令和2017年第24号省长令,加里曼丹省中部森林和土地火灾防治政策分预防政策和处理森林和土地火灾政策两个阶段实施。然而,在实施中,它优先考虑扑灭森林和土地火灾的政策,因为它具有更大的经济、社会、教育和健康影响。加里曼丹省中部预防和处理森林和土地火灾的努力受到人力资源不足、预算有限以及缺乏设施和基础设施的制约。关键词:政策分析;预防;处理
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引用次数: 0
Efficacy of Butanolic Fraction of Cocos Nucifera's Root Aqueous Extract on Induced Anemia Treatment 椰子根水提物丁醇醇部分对诱导性贫血的治疗作用
Pub Date : 2021-04-07 DOI: 10.5539/IJB.V13N1P8
Ap Tchogou, M. Sènou, F. Agbogba, J. Lokonon, S. E. Medoatinsa, C. P. A. Dossa, F. Loko, A. Agbonon, A. Sezan
Cocos nucifera was a coastal plant whose roots were used in pharmacopoeia to treat anemia in Benin. The aqueous extract from its roots stimulated the synthesis of hemoglobin. The aim of this work was to test in vivo the efficacy of the butanolic fraction of the extract in the treatment of anemia. Methods: Wistar rats were anemic with phenylhydrazine for two days. From D2 to D15, some were treated by gavage with the butanolic fraction of the aqueous extract of Cocos nucifera roots at the dose of 40 mg or 60 mg/kg of body weight/day, others were treated with vitafer (an anti-anemic drug) or with distilled water. The rats blood were collected on days D0, D2, D7, D10 and D15 for the complete blood count and the osmotic resistance of the red blood cells. Results: On D2, phenylhydrazine significantly lowered the hemoglobin level and the number of red blood cells, which were respectively corrected on D10 and D15 by the fraction of extract with release of hypochromic macrocytes. However, the effect was slower than that of the crude extract, was not specific to erythropoiesis because it also stimulated thrombopoiesis and was not dose-dependent. Conclusion: The butanolic fraction of the aqueous extract of Cocos nucifera roots corrected anemia by stimulation of hematopoiesis. The observed biological activity would probably be linked to anthocyanins which are mainly isolated by butanol. These results contribute to a better knowledge of bioactive compounds of our antianemic plants.
椰子树是一种沿海植物,其根在贝宁药典中用于治疗贫血。其根部的水提取物刺激了血红蛋白的合成。这项工作的目的是在体内测试提取物的丁醇部分在治疗贫血的功效。方法:用苯肼致Wistar大鼠贫血2 d。从D2到D15,一部分小鼠以40 mg或60 mg/kg体重/天的剂量灌胃椰子根水提物丁醇组分,另一部分小鼠以维生素(一种抗贫血药物)或蒸馏水处理。于D0、D2、D7、D10、D15 d采集大鼠血液,测定全血细胞计数和红细胞渗透阻力。结果:在D2时,苯肼显著降低血红蛋白水平和红细胞数量,在D10和D15时,分别用低色巨细胞释放提取物的组分加以纠正。然而,效果比粗提物慢,对红细胞生成没有特异性,因为它也刺激了血小板生成,并且不具有剂量依赖性。结论:椰子根水提物丁醇组分具有促进造血的作用。所观察到的生物活性可能与主要由丁醇分离的花青素有关。这些结果有助于更好地了解我们的抗贫血植物的生物活性化合物。
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引用次数: 2
Fetal Heart Rate Extraction using NLMS Algorithm 利用NLMS算法提取胎儿心率
Pub Date : 2021-04-07 DOI: 10.46300/91011.2021.15.8
K. Ricky, M. Arjuna, S. Aminifar
This project develops a fetal heart rate (FHR) extraction application to analyze the fetus activity in the mother uterus. Several methods are available that can be used to detect FHR such as using the fetal electrocardiogram (FECG) that generated by fetus’ heart. Extracting FECG signals is considered a major challenge while the fetus is inside the mother uterus. Normalized Least Mean Square (NLMS) algorithm is one of adaptive filters that is chosen as adaptive filter to get FECG. Pan Tompkins algorithm is used for tracking R-peaks of heartbeat pulses of FECG signal. After detecting the RR interval a formula is used to calculate the bpm (heartbeat per minute) of FECG. Abdominal and direct FECG (ADFECG) database will be used to evaluate the implemented techniques as it has reference signal. At the end of research, calculated FHR is varied from 125.4 bpm to 130.3 bpm. When comparison is done between abdominal ECG (AECG) and direct FECG (DFECG), the error of FHR is 0.1%. The accuracy of R-peaks extraction is 100% where all R-peaks are detected by implemented techniques. MATLAB is used for signal simulations. This system will have ability to interpret the non-invasive FECG (NIFECG) database and compute its FHR. Keywords—NLMS Algorithm, Pan Tompkins Algorithm and Fetal Heart Rate Extraction.
本项目开发胎儿心率(FHR)提取应用程序来分析胎儿在母体子宫的活动。有几种方法可用于检测FHR,如使用胎儿心脏产生的胎儿心电图(FECG)。胎儿在母体子宫内时,提取FECG信号被认为是一个重大挑战。归一化最小均方(NLMS)算法是一种自适应滤波算法,被用来作为自适应滤波来获得FECG。采用Pan Tompkins算法对FECG信号的心跳脉冲r峰进行跟踪。检测到RR间隔后,用公式计算feg的bpm(心跳/分钟)。腹部和直接FECG (ADFECG)数据库将用于评估实施的技术,因为它有参考信号。在研究结束时,计算的FHR在125.4 bpm到130.3 bpm之间变化。腹部心电图(AECG)与直接心电图(DFECG)比较,FHR误差为0.1%。r -峰提取的准确性为100%,其中所有r -峰都被实现的技术检测到。使用MATLAB进行信号仿真。该系统将能够解释无创FECG (NIFECG)数据库并计算其FHR。关键词:nlms算法,Pan Tompkins算法,胎儿心率提取
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引用次数: 1
Cloning and Sequence Analysis of 5S Ribosomal RNA Gene(s) and Associated Intergenic Spacer Regions in Carica Species 加勒比种5S核糖体RNA基因及相关基因间隔区的克隆与序列分析
Pub Date : 2021-03-30 DOI: 10.5539/IJB.V13N1P1
Mahipal Singh, P. Yadav, A. Yadav
The 5S ribosomal RNA gene(s) and their associated intergenic spacer regions were amplified from Carica papaya and Carica quercifolia by polymerase chain reaction. Both Carica species exhibited differently sized amplification products. Sequence analysis of these PCR products revealed that the 5S rRNA genes are arranged as tandem repeats in these regions. Sequence data revealed that the 5S rRNA gene from Carica quercifolia was 119 bp in length. Sequence variation was observed in various 5S rRNA gene copies cloned from Carica quercifolia. Only truncated 5S rRNA gene but with its full spacer region was recovered from Carica papaya. Interestingly, intergenic spacer sequence cloned from Carica papaya contained two specific domains, a 30bp “CT” rich domain exhibiting 95-100% homology to several human chromosomes and a domain matching with mitrocomin precursor, a photoprotein from Mitrocoma cellularia. The role of 5S rRNA gene and their spacer regions in discerning the germplasm and in adaptation of the species is discussed.
采用聚合酶链反应从番木瓜和槲皮中扩增出5S核糖体RNA基因及其相关基因间隔区。两种Carica扩增产物大小不同。PCR产物序列分析表明,5S rRNA基因在这些区域呈串联重复序列排列。序列数据显示,槲皮5S rRNA基因长度为119 bp。从槲皮中克隆的多个5S rRNA基因拷贝序列存在差异。在番木瓜中只发现了截断的5S rRNA基因,但有完整的间隔区。有趣的是,从番木瓜中克隆的基因间间隔序列包含两个特定的结构域,一个是30bp的“CT”丰富结构域,与几种人类染色体具有95-100%的同源性,另一个是与mitrocomin前体匹配的结构域,mitrocomin前体是一种来自Mitrocoma cellularia的光蛋白。讨论了5S rRNA基因及其间隔区在种质识别和物种适应中的作用。
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引用次数: 0
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International Journal of Biology
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