Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233600
Prashanth M. R., Pavithra Shree B. E., Namratha K. B.
Background: Accurate temperature assessment is essential in neonatal care as minor temperature changes can have a significant impact on the health and well-being of newborns. The purpose of this study was to compare the performance of three different types of thermometers, including non-contact infrared, digital, and mercury thermometers, for temperature assessment in newborns. Methods: This was a prospective, comparative study conducted between April 2022 and August 2022 in Cheluvamba hospital, Mysuru. A total of 400 healthy newborns were included in the study. Temperature readings were taken from the mid-forehead non-contact infrared thermometer and axilla using digital and mercury thermometers, while maintaining aseptic precautions. Parental oral consent was obtained for participation. Results: The mean temperature recorded with the digital thermometer in the axilla was statistically higher than that recorded with the mercury thermometer. The non-contact infrared thermometer showed a strong positive correlation with the mercury thermometer for the axilla region. Conclusions: The digital thermometer is a useful device for easy and valid measurement of skin temperature in newborns, especially when applied to the axilla. The findings suggest that the use of digital thermometers for axillary temperature measurement in neonates is supported by previous studies, which have reported their accuracy and reliability in comparison to mercury thermometers. The non-contact infrared thermometer may have limitations and its accuracy may vary depending on the site of measurement. The use of digital thermometers for neonatal temperature measurement may be more convenient, less hazardous, and equally reliable compared to traditional mercury thermometers.
{"title":"Temperature assessment in newborn: a better method","authors":"Prashanth M. R., Pavithra Shree B. E., Namratha K. B.","doi":"10.18203/2349-3291.ijcp20233600","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233600","url":null,"abstract":"Background: Accurate temperature assessment is essential in neonatal care as minor temperature changes can have a significant impact on the health and well-being of newborns. The purpose of this study was to compare the performance of three different types of thermometers, including non-contact infrared, digital, and mercury thermometers, for temperature assessment in newborns. Methods: This was a prospective, comparative study conducted between April 2022 and August 2022 in Cheluvamba hospital, Mysuru. A total of 400 healthy newborns were included in the study. Temperature readings were taken from the mid-forehead non-contact infrared thermometer and axilla using digital and mercury thermometers, while maintaining aseptic precautions. Parental oral consent was obtained for participation. Results: The mean temperature recorded with the digital thermometer in the axilla was statistically higher than that recorded with the mercury thermometer. The non-contact infrared thermometer showed a strong positive correlation with the mercury thermometer for the axilla region. Conclusions: The digital thermometer is a useful device for easy and valid measurement of skin temperature in newborns, especially when applied to the axilla. The findings suggest that the use of digital thermometers for axillary temperature measurement in neonates is supported by previous studies, which have reported their accuracy and reliability in comparison to mercury thermometers. The non-contact infrared thermometer may have limitations and its accuracy may vary depending on the site of measurement. The use of digital thermometers for neonatal temperature measurement may be more convenient, less hazardous, and equally reliable compared to traditional mercury thermometers.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139229057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233596
M. Z. Hossain, M. N. Ali, Amar Kumar Saha, S. Shahid, Shantona Rani Paul
Background: Pediatric blunt abdominal trauma with organ injuries is a critical issue in Bangladesh, lacking sufficient research. This study focuses on managing such cases in a tertiary hospital. Objectives were to assess clinical characteristics, injury patterns, and outcomes of pediatric patients with blunt abdominal trauma and organ injuries. It aims to identify causes, associated injuries, and hospital stay durations. Methods: A prospective study of 142 pediatric patients aged 1-12 was conducted at Rajshahi medical college hospital study period January 2020 to December 2021. In addition, this study aimed to identify and grade solid organ injuries according to the American association for the surgery of trauma organ injury scale. Results: Prevalence of hepatic injuries (76.8%), solid organ injuries (90.1%), road traffic accidents (71.8%), falls from height (25.4%). Most received conservative treatment, had short hospital stays, and a 7% mortality rate. Gender had no significant impact on organ injuries (p>0.001). Among the causes, 84.5% had hepatic injuries, 15.5% had spleen injuries due to road traffic accidents, and 58.3% had injuries from falls from height, with a highly significant cause-organ injury relationship (p<0.001). Conclusions: pediatric blunt abdominal injuries in Bangladesh affect various organs, primarily in males and school-aged children, primarily due to road accidents. Timely surgical intervention and preventive measures are crucial for improved outcomes.
{"title":"Paediatric blunt abdominal trauma with organ injury: a comprehensive analysis of cases at a tertiary hospital in Bangladesh","authors":"M. Z. Hossain, M. N. Ali, Amar Kumar Saha, S. Shahid, Shantona Rani Paul","doi":"10.18203/2349-3291.ijcp20233596","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233596","url":null,"abstract":"Background: Pediatric blunt abdominal trauma with organ injuries is a critical issue in Bangladesh, lacking sufficient research. This study focuses on managing such cases in a tertiary hospital. Objectives were to assess clinical characteristics, injury patterns, and outcomes of pediatric patients with blunt abdominal trauma and organ injuries. It aims to identify causes, associated injuries, and hospital stay durations. Methods: A prospective study of 142 pediatric patients aged 1-12 was conducted at Rajshahi medical college hospital study period January 2020 to December 2021. In addition, this study aimed to identify and grade solid organ injuries according to the American association for the surgery of trauma organ injury scale. Results: Prevalence of hepatic injuries (76.8%), solid organ injuries (90.1%), road traffic accidents (71.8%), falls from height (25.4%). Most received conservative treatment, had short hospital stays, and a 7% mortality rate. Gender had no significant impact on organ injuries (p>0.001). Among the causes, 84.5% had hepatic injuries, 15.5% had spleen injuries due to road traffic accidents, and 58.3% had injuries from falls from height, with a highly significant cause-organ injury relationship (p<0.001). Conclusions: pediatric blunt abdominal injuries in Bangladesh affect various organs, primarily in males and school-aged children, primarily due to road accidents. Timely surgical intervention and preventive measures are crucial for improved outcomes.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: This study was designed to analyze and evaluate the potential pathogenic genomic imbalance in children with unexplained intellectual disability (ID) and/or developmental delay (DD) and its association with phenotypes, and to investigate the value of array-based comparative genomic hybridization (array-CGH). Methods: A total of 72 Children with ID/DD were evaluated by array-CGH for detection of genomic copy number variations (CNVs). Results: The results of the array-CGH revealed that 10(14%) of the 72 patients had pathogenic CNVs, in that six cases had pathogenic CNV in a single chromosome, 2 cases had multiple microdeletions and 2 cases had combined microdeletion and microduplication, 2 cases had pathogenic CNVs in chromosome 1p36 and Xq28 region. One case had variation of unknown significance in chromosome region 15q11.2. Large bands of copy neutral loss of heterozygosity were detected in 2 cases comprising more than 10% of genome. Conclusions: Array-CGH being a high-throughput and rapid tool, allows for the etiological diagnosis in some of the children with unexplained ID/DD.
{"title":"Application of array comparative genomic hybridization in clinical diagnostics of intellectual disability/developmental delay in children","authors":"Komal Uppal, Lakshay Rana, S. Polipalli, Somesh Kumar, Ankur Jindal, Seema Kapoor","doi":"10.18203/2349-3291.ijcp20233608","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233608","url":null,"abstract":"Background: This study was designed to analyze and evaluate the potential pathogenic genomic imbalance in children with unexplained intellectual disability (ID) and/or developmental delay (DD) and its association with phenotypes, and to investigate the value of array-based comparative genomic hybridization (array-CGH). Methods: A total of 72 Children with ID/DD were evaluated by array-CGH for detection of genomic copy number variations (CNVs). Results: The results of the array-CGH revealed that 10(14%) of the 72 patients had pathogenic CNVs, in that six cases had pathogenic CNV in a single chromosome, 2 cases had multiple microdeletions and 2 cases had combined microdeletion and microduplication, 2 cases had pathogenic CNVs in chromosome 1p36 and Xq28 region. One case had variation of unknown significance in chromosome region 15q11.2. Large bands of copy neutral loss of heterozygosity were detected in 2 cases comprising more than 10% of genome. Conclusions: Array-CGH being a high-throughput and rapid tool, allows for the etiological diagnosis in some of the children with unexplained ID/DD.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233601
Bhaswati Ghoshal, Akhila Andra
Background: SARS-COV-2 manifestations in neonates acquired in the later part of neonatal life, were compared over 2 peaks over April-May 2021 (2nd wave) and (December 2021 to January 2022) (3rd wave). Setting: Study was done in Calcutta National Medical College, a tertiary care center of eastern India. Methods: Cross sectional study was done among the admitted neonatal cases in COVID designated NICU. Neonates acquired the COVID-19 infection after birth. All mothers were tested negative during delivery. Results: 40 neonates were admitted in April-May 2021 in COVID designated NICU and 42 neonates were admitted in December to January 2022. 66.6% mothers were COVID-19 RTPCR positive in December-January 2022 cases than 49.3% mothers in April-May 2021. These mothers were tested as COVID-19 negative at the time of delivery. None of the mothers were vaccinated in 2021 cases. Only 13.3% mothers received two doses of COVID-19 vaccination in December-January 2022 cases. Initial complaints were lethargic, not arousable (22.7%) and poor respiratory effort (27.5%) in December-January 22 cases. Respiratory (rapid breathing 40%) and gastrointestinal symptoms (diarrhoea 25.3%) were more predominant in neonates who were admitted in April-May 2021 than neonates who presented on January 2022. Hospital stay was significantly less in neonates in December-January 2022 (p=0.005). Genome sequencing revealed Omicron BA-2 in January 2022. Conclusions: Clinical presentations differ in neonates in April-May 2021 and December-January 2022 probably due to difference in the nature of the virus.
{"title":"Comparison of clinical presentation and outcome of neonatal SARS-COV2 during second wave from April-May 2021 and third wave from December 2021 to January 2022 in a tertiary care hospital in Eastern India","authors":"Bhaswati Ghoshal, Akhila Andra","doi":"10.18203/2349-3291.ijcp20233601","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233601","url":null,"abstract":"Background: SARS-COV-2 manifestations in neonates acquired in the later part of neonatal life, were compared over 2 peaks over April-May 2021 (2nd wave) and (December 2021 to January 2022) (3rd wave). Setting: Study was done in Calcutta National Medical College, a tertiary care center of eastern India. Methods: Cross sectional study was done among the admitted neonatal cases in COVID designated NICU. Neonates acquired the COVID-19 infection after birth. All mothers were tested negative during delivery. Results: 40 neonates were admitted in April-May 2021 in COVID designated NICU and 42 neonates were admitted in December to January 2022. 66.6% mothers were COVID-19 RTPCR positive in December-January 2022 cases than 49.3% mothers in April-May 2021. These mothers were tested as COVID-19 negative at the time of delivery. None of the mothers were vaccinated in 2021 cases. Only 13.3% mothers received two doses of COVID-19 vaccination in December-January 2022 cases. Initial complaints were lethargic, not arousable (22.7%) and poor respiratory effort (27.5%) in December-January 22 cases. Respiratory (rapid breathing 40%) and gastrointestinal symptoms (diarrhoea 25.3%) were more predominant in neonates who were admitted in April-May 2021 than neonates who presented on January 2022. Hospital stay was significantly less in neonates in December-January 2022 (p=0.005). Genome sequencing revealed Omicron BA-2 in January 2022. Conclusions: Clinical presentations differ in neonates in April-May 2021 and December-January 2022 probably due to difference in the nature of the virus.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139231763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233597
Shweta K. Shah, Anand K. Jha, Satish Sharma, Sanjay Gupta
Background: Neonatal hyperbilirubinemia (NH) is the most common abnormality seen during the neonatal period. It affects nearly 60% of term and 80% of preterm neonates during the first week of life. Early discharge of healthy term and late preterm newborns after normal vaginal delivery is a common practice however there are reports of bilirubin induced brain damage (kernicterus) occurring in these infants. Therefore, to ascertain whether cord albumin can be used as a reliable indicator for predicting neonatal hyperbilirubinemia. Methods: A tertiary care hospital-based cross-sectional study was conducted in 142 healthy late preterm and term newborns of either gender with icterus appearing only after 24 hour of life with no other illness using a non-probability sampling method. Data analysis was done using statistical package for the social sciences (SPSS) version 16. Chi-square was used to determine the association between cord albumin and hyperbilirubinemia. Results: There is a significant negative correlation between cord albumin and serum bilirubin at 72-96 hours of life (p=0.001). A total of 142 healthy late preterm and term neonates included. The study group based on Cord serum albumin (CSA) levels ≤2.8 g/dl, 2.9-3.3 g/dl, and ≥3.4 g/dl shows 77.27%, 22.7% and none respectively developed NH requiring phototherapy. According to receiver operating curve (ROC) analysis, the cutoff point of 2.75 g/dl provides the best sensitivity and specificity result. Conclusions: Cord serum albumin level ≥3.4 g/dl are probably safe for early discharge whereas cord serum albumin level <3.4 g/dl will need a close follow-up to check for the development of jaundice.
{"title":"Association of neonatal hyperbilirubinemia with cord albumin among term appropriate for gestational age neonates","authors":"Shweta K. Shah, Anand K. Jha, Satish Sharma, Sanjay Gupta","doi":"10.18203/2349-3291.ijcp20233597","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233597","url":null,"abstract":"Background: Neonatal hyperbilirubinemia (NH) is the most common abnormality seen during the neonatal period. It affects nearly 60% of term and 80% of preterm neonates during the first week of life. Early discharge of healthy term and late preterm newborns after normal vaginal delivery is a common practice however there are reports of bilirubin induced brain damage (kernicterus) occurring in these infants. Therefore, to ascertain whether cord albumin can be used as a reliable indicator for predicting neonatal hyperbilirubinemia. Methods: A tertiary care hospital-based cross-sectional study was conducted in 142 healthy late preterm and term newborns of either gender with icterus appearing only after 24 hour of life with no other illness using a non-probability sampling method. Data analysis was done using statistical package for the social sciences (SPSS) version 16. Chi-square was used to determine the association between cord albumin and hyperbilirubinemia. Results: There is a significant negative correlation between cord albumin and serum bilirubin at 72-96 hours of life (p=0.001). A total of 142 healthy late preterm and term neonates included. The study group based on Cord serum albumin (CSA) levels ≤2.8 g/dl, 2.9-3.3 g/dl, and ≥3.4 g/dl shows 77.27%, 22.7% and none respectively developed NH requiring phototherapy. According to receiver operating curve (ROC) analysis, the cutoff point of 2.75 g/dl provides the best sensitivity and specificity result. Conclusions: Cord serum albumin level ≥3.4 g/dl are probably safe for early discharge whereas cord serum albumin level <3.4 g/dl will need a close follow-up to check for the development of jaundice.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233602
Sonal S. Joshi, Seemi A. Retharekar
Background: Incidence of pulmonary diseases in urban children is on the rise. Peak expiratory flow rate, a component of pulmonary function tests, is a useful measure for initial pulmonary assessment. It is easily implementable on large population due to its simplicity. Studies presenting such data for Indian children are severely lacking, as PEFR is anthropometric, population and region specific. The present study aimed to establish an equation for predicting PEFR in urban children in Pune city in western Maharashtra, India. Methods: The cross-sectional study was done in Pune, Maharashtra, India. Children from different schools were selected by cluster sampling. The number of participants screened was 2100 of which 1760 were selected. Best of three readings of PEFR was recorded for each child using an EU Scale Peak Flow meter (Breath-O meter, Cipla). Anthropometric data like height, weight, chest expansion, waist/hip ratio were measured and BMI was calculated along with PEFR of each child. Results: Out of the 1760 children included in the study 933 (53%) were boys and 827 (47%) were girls. The stepwise regression analyses were carried out using age, height, weight and waist/hip ratio as predictor variables. Conclusions: Final regression equation was derived using height. Approximately 80% of the data was used for prediction of regression equation and remaining 20% data was used as a control group to validate the derived equation. The regression equation formulated shall offer a predicted PEFR value as guideline for healthcare workers in Pune city, Maharashtra, India.
{"title":"Regression equations for peak expiratory flow rate in children aged 5-10 years of Western Maharashtra, India: a cross-sectional study","authors":"Sonal S. Joshi, Seemi A. Retharekar","doi":"10.18203/2349-3291.ijcp20233602","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233602","url":null,"abstract":"Background: Incidence of pulmonary diseases in urban children is on the rise. Peak expiratory flow rate, a component of pulmonary function tests, is a useful measure for initial pulmonary assessment. It is easily implementable on large population due to its simplicity. Studies presenting such data for Indian children are severely lacking, as PEFR is anthropometric, population and region specific. The present study aimed to establish an equation for predicting PEFR in urban children in Pune city in western Maharashtra, India. Methods: The cross-sectional study was done in Pune, Maharashtra, India. Children from different schools were selected by cluster sampling. The number of participants screened was 2100 of which 1760 were selected. Best of three readings of PEFR was recorded for each child using an EU Scale Peak Flow meter (Breath-O meter, Cipla). Anthropometric data like height, weight, chest expansion, waist/hip ratio were measured and BMI was calculated along with PEFR of each child. Results: Out of the 1760 children included in the study 933 (53%) were boys and 827 (47%) were girls. The stepwise regression analyses were carried out using age, height, weight and waist/hip ratio as predictor variables. Conclusions: Final regression equation was derived using height. Approximately 80% of the data was used for prediction of regression equation and remaining 20% data was used as a control group to validate the derived equation. The regression equation formulated shall offer a predicted PEFR value as guideline for healthcare workers in Pune city, Maharashtra, India.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"230 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233599
Sravanthi Kosuri, Satheesh C.
Background: The aim was to develop age- and sex-specific waist circumference percentiles for school children aged 5 to 17 years in Chennai. Methods: This was a cross-sectional study done among school children in Chennai. A total of 1124 children aged 5 to 17 years were included in the study, of which 540 were female and 584 were male. Anthropometric details, weight, height, waist circumference (WC), and body mass index (BMI) were measured. The percentiles for waist circumference according to age and gender was done using SPSS 28.0. Khadilkar et al suggested a cutoff of 70th centile screening for central obesity and risk for metabolic syndrome; similarly, we plotted 70th WC percentiles. Results: Age- and sex-specific WC percentiles (5th, 10th, 15th, 25th, 50th, 75th, 85th, 90th, 95th) were provided. Our study revealed a higher prevalence of overweight or obesity (40.6%) in children (overweight: 21.08%, obesity: 19.50%) when compared to other school studies. BMI in children with WC >70th percentile revealed 87% of them were overweight or obese. A strong and significant statistical correlation was observed between waist circumference and overweight or obesity (p<0.001). Conclusions: Age- and sex-specific reference curve percentiles for waist circumference and cut-off values greater than the 70th percentile for schoolchildren were provided. We strongly recommend utilising waist circumference as an anthropometrical tool to quantify central obesity in schoolchildren.
{"title":"Age and sex-specific waist circumference percentiles among school children in Chennai","authors":"Sravanthi Kosuri, Satheesh C.","doi":"10.18203/2349-3291.ijcp20233599","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233599","url":null,"abstract":"Background: The aim was to develop age- and sex-specific waist circumference percentiles for school children aged 5 to 17 years in Chennai. Methods: This was a cross-sectional study done among school children in Chennai. A total of 1124 children aged 5 to 17 years were included in the study, of which 540 were female and 584 were male. Anthropometric details, weight, height, waist circumference (WC), and body mass index (BMI) were measured. The percentiles for waist circumference according to age and gender was done using SPSS 28.0. Khadilkar et al suggested a cutoff of 70th centile screening for central obesity and risk for metabolic syndrome; similarly, we plotted 70th WC percentiles. Results: Age- and sex-specific WC percentiles (5th, 10th, 15th, 25th, 50th, 75th, 85th, 90th, 95th) were provided. Our study revealed a higher prevalence of overweight or obesity (40.6%) in children (overweight: 21.08%, obesity: 19.50%) when compared to other school studies. BMI in children with WC >70th percentile revealed 87% of them were overweight or obese. A strong and significant statistical correlation was observed between waist circumference and overweight or obesity (p<0.001). Conclusions: Age- and sex-specific reference curve percentiles for waist circumference and cut-off values greater than the 70th percentile for schoolchildren were provided. We strongly recommend utilising waist circumference as an anthropometrical tool to quantify central obesity in schoolchildren.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233603
Sushrutha K. P., Hamsa M., Lingaraju N., Sampath Kumar C.
Background: Neonatal sepsis is responsible for approximately 15% of all neonatal deaths in the world. Despite of availability in advanced medical healthcare facilities for mother and neonates, incidence of mortality secondary to sepsis especially in developing countries like India is more common. Metabolic acidosis is the most common form of acid base imbalance in neonatal sepsis which can be analyzed with increased levels of base excess. Hence early diagnosis of neonatal sepsis can be done by determining base excess. Methods: This is a prospective observational study conducted in NICU at Cheluvamba Hospital, Mysore. 73 term neonates with suspected sepsis were enrolled in the study who were on regular follow-up and treatment till death/discharged from NICU. Base excess value is obtained from the arterial blood gas analysis from each subject and it was compared with survivor and non-survivor group along with other study parameter Results: Out of 73 subjects, incidence of non survivors group with severe increase in base excess is 75%. To predict the mortality, we compared it with standard base excess which showed the prediction of more than 60%, with significant AOC (0.827) of very near to one in ROC curve, with statistically significant (p<0.001) sensitivity of 92.59%, specificity of 63.04%, positive predictive value of 59.5%, negative predictive value of 93.5%. Conclusions: In present study we have proved that base excess is an important parameter for the early diagnosis and for early intervention in neonatal sepsis.
{"title":"Base excess as a predictor of neonatal mortality in neonatal sepsis","authors":"Sushrutha K. P., Hamsa M., Lingaraju N., Sampath Kumar C.","doi":"10.18203/2349-3291.ijcp20233603","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233603","url":null,"abstract":"Background: Neonatal sepsis is responsible for approximately 15% of all neonatal deaths in the world. Despite of availability in advanced medical healthcare facilities for mother and neonates, incidence of mortality secondary to sepsis especially in developing countries like India is more common. Metabolic acidosis is the most common form of acid base imbalance in neonatal sepsis which can be analyzed with increased levels of base excess. Hence early diagnosis of neonatal sepsis can be done by determining base excess. Methods: This is a prospective observational study conducted in NICU at Cheluvamba Hospital, Mysore. 73 term neonates with suspected sepsis were enrolled in the study who were on regular follow-up and treatment till death/discharged from NICU. Base excess value is obtained from the arterial blood gas analysis from each subject and it was compared with survivor and non-survivor group along with other study parameter Results: Out of 73 subjects, incidence of non survivors group with severe increase in base excess is 75%. To predict the mortality, we compared it with standard base excess which showed the prediction of more than 60%, with significant AOC (0.827) of very near to one in ROC curve, with statistically significant (p<0.001) sensitivity of 92.59%, specificity of 63.04%, positive predictive value of 59.5%, negative predictive value of 93.5%. Conclusions: In present study we have proved that base excess is an important parameter for the early diagnosis and for early intervention in neonatal sepsis.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139231263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233615
Deepa Shetty, Kira Pariath, Paras Patel, Sanjay Vansh
Urbach-Wiethe disease also known as lipoid proteinosis (LP) is a rare autosomal recessive Geno dermatosis.1 It is characterized by the deposition of an amorphous hyaline material in the skin, mucosa and viscera and is also known as cutaneous-mucosal hyalinosis.2,3 Parental consanguinities is identified in approximately 20% of Urbach-Wiethe disease cases. The classic manifestation due to laryngeal infiltration is a hoarse cry with its onset in infancy. Skin and mucous membrane changes become clinically apparent important consequences.4 Rarely, the central nervous system and respiratory tract may be involved resulting in seizures and airway obstruction, respectively. The lifespan is generally normal. We report a case of Urbach-Wiethe disease in a 6-year-old boy with hoarseness of voice who was started on oral acitretin therapy following his diagnosis. Oral acitretin can prove useful in cases of lipoid proteinosis who present with hoarseness of voice or vocal cord palsy. The mutations in the gene encoding extracellular matrix protein 1 (ECM1) have been linked to lipoid proteinosis. Even though no effective treatment is known, acitretin has proved to reverse hoarseness of voice in few reported cases and was started in our case as it was his chief presenting complaint.
{"title":"Urbach-Wiethe disease: a rare pediatric case report","authors":"Deepa Shetty, Kira Pariath, Paras Patel, Sanjay Vansh","doi":"10.18203/2349-3291.ijcp20233615","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233615","url":null,"abstract":"Urbach-Wiethe disease also known as lipoid proteinosis (LP) is a rare autosomal recessive Geno dermatosis.1 It is characterized by the deposition of an amorphous hyaline material in the skin, mucosa and viscera and is also known as cutaneous-mucosal hyalinosis.2,3 Parental consanguinities is identified in approximately 20% of Urbach-Wiethe disease cases. The classic manifestation due to laryngeal infiltration is a hoarse cry with its onset in infancy. Skin and mucous membrane changes become clinically apparent important consequences.4 Rarely, the central nervous system and respiratory tract may be involved resulting in seizures and airway obstruction, respectively. The lifespan is generally normal. We report a case of Urbach-Wiethe disease in a 6-year-old boy with hoarseness of voice who was started on oral acitretin therapy following his diagnosis. Oral acitretin can prove useful in cases of lipoid proteinosis who present with hoarseness of voice or vocal cord palsy. The mutations in the gene encoding extracellular matrix protein 1 (ECM1) have been linked to lipoid proteinosis. Even though no effective treatment is known, acitretin has proved to reverse hoarseness of voice in few reported cases and was started in our case as it was his chief presenting complaint.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139234482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.18203/2349-3291.ijcp20233595
M. A. Sultana, M. J. Chowdhury, A. F. M. Farhad, Mohammad Ahad Adnan, Wahida Khanam, M. A. Akter
Background: Nutritional status in children with chronic disease like cerebral palsy is crucial in growth and development. This study was conducted with the aim of assessing nutritional status of children with CP by using anthropometric indices and few associated factors. Methods: This cross-sectional study was conducted in ICMH, Dhaka from July 2020 to June 2021. A total of 30 children underwent proper history taking and thorough anthropometric examinations. Twenty-four hours dietary recall method was used for estimating approximate calorie intake. Results: Out of 30 children two thirds age was under 60 months and mean±SD age was 59.2±33.1 months. 60.0% children were male and majority (86.7%) of children were found calorie intake ≤50 percent of adequate calorie intake. Most (83.3%) of studied children presented with spastic quadriplegia, in according to age, 2 group were created (<60 months & ≥60 months). In children under 5 years age, 75.0% were severely wasted, 35.0% were severely stunted, 85.0% were severely underweight and 75.0% were severely malnourished. In ≥5 years, 60.0% were severely stunted and 90.0% were underweight or thin. Wasting andunderweight had significant association with swallowing difficulty and inadequate calorie intake in under 5 years age group and stunting had significant association with those factors in ≥5 years age group. Conclusions: This study shows that undernutrition affects a large number of children with CP in a selected tertiary care hospital. Risk of severe undernutrition increases with swallowing difficulty.
{"title":"Nutritional status of children with cerebral palsy in a selected tertiary care hospital","authors":"M. A. Sultana, M. J. Chowdhury, A. F. M. Farhad, Mohammad Ahad Adnan, Wahida Khanam, M. A. Akter","doi":"10.18203/2349-3291.ijcp20233595","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20233595","url":null,"abstract":"Background: Nutritional status in children with chronic disease like cerebral palsy is crucial in growth and development. This study was conducted with the aim of assessing nutritional status of children with CP by using anthropometric indices and few associated factors. Methods: This cross-sectional study was conducted in ICMH, Dhaka from July 2020 to June 2021. A total of 30 children underwent proper history taking and thorough anthropometric examinations. Twenty-four hours dietary recall method was used for estimating approximate calorie intake. Results: Out of 30 children two thirds age was under 60 months and mean±SD age was 59.2±33.1 months. 60.0% children were male and majority (86.7%) of children were found calorie intake ≤50 percent of adequate calorie intake. Most (83.3%) of studied children presented with spastic quadriplegia, in according to age, 2 group were created (<60 months & ≥60 months). In children under 5 years age, 75.0% were severely wasted, 35.0% were severely stunted, 85.0% were severely underweight and 75.0% were severely malnourished. In ≥5 years, 60.0% were severely stunted and 90.0% were underweight or thin. Wasting andunderweight had significant association with swallowing difficulty and inadequate calorie intake in under 5 years age group and stunting had significant association with those factors in ≥5 years age group. Conclusions: This study shows that undernutrition affects a large number of children with CP in a selected tertiary care hospital. Risk of severe undernutrition increases with swallowing difficulty.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139233773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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