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Climate-Induced Heat and the Mental Health of Older Adults: An Overlooked Challenge 气候诱发的高温和老年人的心理健康:一个被忽视的挑战
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-12 DOI: 10.1002/gps.70157
John Jamir Benzon R. Aruta
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引用次数: 0
Rapid Review of Interventions Designed to Enhance Personalised Care for People With Dementia When There Are Concerns About Reduced Awareness of Difficulties 当人们担心对困难的认识降低时,旨在加强对痴呆症患者个性化护理的干预措施的快速回顾
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-08 DOI: 10.1002/gps.70153
Catherine M. Alexander, Hannah Earle, Anthony Martyr, Linda Clare

Objectives

Awareness of difficulties varies in people with dementia. Low awareness, also termed anosognosia, has been implicated in carer stress and safety concerns, and can be a barrier to effective clinical communication. Little is known about how to manage situations arising from low awareness. This review looked for evidence of existing interventions to enhance care in situations regarding low awareness, and considered their utility, feasibility and acceptability when delivering personalised care.

Methods

We used systematic review methodology, adapted for a rapid timeline, searching five databases and grey literature sources. The review built on an earlier scoping review about measuring awareness in dementia. The protocol was registered on PROSPERO (CRD42024626367). Interventions were included if targeted at people with any dementia type in any setting, or dyads or informal carers, or clinicians. Interventions of any type were eligible where awareness had been measured and addressed, and quantitative outcome data were available. Risk of bias of included articles was assessed. The review is reported as a narrative synthesis.

Results

From the database search, 6042 articles were screened, with additional findings from grey literature. Seven articles were included, describing heterogenous interventions. Two interventions aimed to enhance awareness as the primary goal. No intervention was aimed at informal carers or clinicians, and none addressed specific everyday concerns arising from low awareness. Five non-pharmacological interventions used methods involving music, a garden, a cognitive programme, interview-based psychosocial approaches or staff training. These appeared generally acceptable to care recipients, with some feasibility of use, but with limited efficacy. Intervention goals regarding awareness were poorly defined. Outcomes on awareness were mixed in comparison with control groups, with slowing of decline at best. Some improvement in mood, quality of life and coping was observed. Two drug interventions showed a reduction in neuropsychiatric symptoms but limited utility regarding awareness. Available public guidance about awareness issues is relevant but lacks a clear evidence-base.

Conclusions

The review identified evidence gaps for suitable interventions for managing low awareness in dementia. Existing interventions have limited efficacy and application regarding awareness. There is scope for fu

痴呆症患者对困难的认识各不相同。低意识,也被称为病感失认症,与护理人员压力和安全问题有关,并可能成为有效临床沟通的障碍。人们对如何管理由于意识不足而产生的情况知之甚少。本综述寻找现有干预措施的证据,以提高在低意识情况下的护理,并考虑其效用,可行性和可接受性提供个性化护理。方法采用系统综述方法,对5个数据库和灰色文献资源进行检索。该综述建立在早期关于测量痴呆症意识的范围综述的基础上。该协议在PROSPERO上注册(CRD42024626367)。干预措施包括针对任何环境中任何类型的痴呆症患者、双性恋者、非正式护理人员或临床医生。任何类型的干预措施都是合格的,只要已经测量和处理了意识,并且可以获得定量的结果数据。评估纳入文章的偏倚风险。这篇综述是作为一篇叙述性综合报道。结果从数据库检索中,筛选了6042篇文章,另外的发现来自灰色文献。纳入了7篇描述异质性干预措施的文章。两项干预措施的主要目标是提高认识。没有针对非正式护理人员或临床医生的干预措施,也没有针对由低意识引起的具体日常问题。五种非药物干预方法涉及音乐、花园、认知项目、基于访谈的社会心理方法或工作人员培训。这些似乎普遍接受的护理对象,有一定的可行性使用,但效力有限。关于意识的干预目标定义不清。与对照组相比,意识的结果好坏参半,最多只能减缓下降。观察到情绪、生活质量和应对能力有所改善。两种药物干预显示神经精神症状减轻,但对意识的效用有限。现有的关于意识问题的公共指导是相关的,但缺乏明确的证据基础。结论:本综述确定了管理痴呆低意识的适当干预措施的证据差距。现有的干预措施在提高意识方面的效果和应用有限。在这一领域有进一步干预发展的余地。
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引用次数: 0
Analysis of Professionals' Perceptions of Suicide in Older Adults Living in Care Homes 专业人士对安老院长者自杀认知之分析
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-05 DOI: 10.1002/gps.70152
Rita Redondo, Carolina Pinazo-Clapés, Irene Checa, Sacramento Pinazo-Hernandis, Alicia Sales

Introduction

Suicide among older adults living in care homes is a major public health challenge. This study analyses the perceptions and attitudes of professionals working in care homes towards suicidal ideation and suicide attempts in this population.

Method

A total of 338 nursing home professionals from Spain participated in the study. A vignette-based methodology was used, in which cases of suicidal ideation or suicide attempts were described, varying the gender of the actor. Responses to a questionnaire assessed perceived frequency, attention-seeking behaviour, ageism, experienced anxiety, perceived risk and likelihood of future suicide.

Results

Professionals perceived suicidal ideation to be more common and normative in older adults, particularly women. However, they attributed a higher risk and likelihood of suicide to cases involving suicide attempts, which also elicited more anxiety. No significant differences were found in the perception of these situations as ‘attention-seeking behaviour'.

Discussion

Acceptance of suicidal ideation as normal behaviour of suicidal ideation in older adults may reduce the perceived urgency to intervene, highlighting the need for specialised training to help identify risk signals and act promptly. This study highlights the importance of addressing age and gender bias in suicide prevention in care homes and advocates the development of evidence-based strategies.

生活在护理院的老年人自杀是一项重大的公共卫生挑战。本研究分析了在护理院工作的专业人员对这一人群的自杀意念和自杀企图的看法和态度。方法对来自西班牙的338名养老院专业人员进行调查。研究采用了一种基于小插曲的方法,其中描述了自杀意念或自杀企图的案例,并改变了行为者的性别。对问卷的回答评估了感知频率、寻求关注行为、年龄歧视、经历焦虑、感知风险和未来自杀的可能性。结果专业人员认为自杀意念在老年人中更为常见和规范,尤其是女性。然而,他们将更高的自杀风险和可能性归因于涉及自杀企图的案件,这也会引发更多的焦虑。在对这些情况的“寻求注意行为”的感知上,没有发现显著的差异。接受自杀意念作为老年人自杀意念的正常行为可能会降低干预的紧迫性,强调需要进行专门培训,以帮助识别风险信号并迅速采取行动。本研究强调了在养老院预防自杀中解决年龄和性别偏见的重要性,并倡导制定循证策略。
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引用次数: 0
Pareidolic Illusions and Associated Lower Regional Gray Matter Volumes in Community-Dwelling Older Adults Without Dementia: The Arakawa 65+ Study 在社区居住的无痴呆老年人中,幻想幻觉和相关的低区域灰质体积:Arakawa 65+研究
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-03 DOI: 10.1002/gps.70151
Hana Nishida, Shogyoku Bun, Ryo Shikimoto, Hisashi Kida, Kouta Suzuki, Akihiro Takamiya, Jinichi Hirano, Hidehito Niimura, Hiroyuki Uchida, Masaru Mimura

Objectives

Pareidolic illusions involve perceiving meaningful objects in ambiguous or visually complex stimuli. Although seen in dementia, their presence and associated neuroanatomical basis in older adults without dementia remain unclear. Investigating these illusions in this population may reveal early neurodegenerative changes preceding overt dementia. Such insights could support the use of pareidolic illusions as potential early markers for diagnosis and intervention. This study therefore aimed to examine the prevalence and associated neuroanatomical characteristics of pareidolic illusions in community-dwelling older adults without dementia, as assessed by the Noise Pareidolia Test (NPT).

Methods

We investigated the prevalence of pareidolic illusions in older adults aged 65–84 residing in Tokyo, Japan with suspected cognitive decline but without dementia. Participants were classified as cognitively normal or having mild cognitive impairment (MCI) based on standard criteria. Participants underwent NPT, and those who exhibited one or more pareidolic illusions were classified as pareidolia-positive. Additionally, a whole-brain voxel-based morphometry (VBM) of structural magnetic resonance imaging data was performed to assess gray matter volume differences associated with pareidolic illusions.

Results

Pareidolic illusions were present in 35.1% (155/441) of participants. These individuals were significantly older, had shorter years of education, and more likely to be diagnosed with MCI. VBM revealed significantly lower gray matter volume in bilateral temporal clusters—areas associated with face-related visuoperceptual processing—among pareidolia-positive individuals.

Conclusions

Pareidolic illusions were relatively common in community-dwelling older adults without dementia. These illusions may be an early marker of neurodegenerative changes affecting visuoperceptual pathways, and may be detectable using NPT.

空想幻觉包括在模糊或视觉复杂的刺激下感知有意义的物体。尽管在痴呆中也有发现,但它们在无痴呆老年人中的存在及其相关的神经解剖学基础尚不清楚。在这一人群中研究这些幻觉可能会揭示明显痴呆之前的早期神经退行性改变。这些见解可以支持将空想幻觉作为诊断和干预的潜在早期标记。因此,本研究旨在通过噪音空想性视差测试(NPT)来评估社区居住的无痴呆老年人空想性视错觉的患病率和相关的神经解剖学特征。方法我们调查了居住在日本东京的年龄在65-84岁的老年人中,怀疑认知能力下降但没有痴呆的幻想幻觉的患病率。参与者根据标准标准分为认知正常或轻度认知障碍(MCI)。参与者接受了NPT检查,那些表现出一个或多个空想幻觉的人被归类为空想阳性。此外,对结构磁共振成像数据进行基于体素的全脑形态测量(VBM),以评估与空想幻觉相关的灰质体积差异。结果35.1%(155/441)的被试存在幻想幻觉。这些人明显年龄较大,受教育年限较短,更有可能被诊断为轻度认知障碍。VBM显示,在空想阳性个体中,双侧颞叶簇(与面部相关的视觉知觉加工相关的区域)的灰质体积显著降低。结论空想幻觉在社区居住的无痴呆老年人中较为常见。这些幻觉可能是影响视知觉通路的神经退行性变化的早期标志,可以用NPT检测到。
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引用次数: 0
Neural Basis of Anxiety in Dementia With Lewy Bodies 路易体痴呆患者焦虑的神经基础
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-03 DOI: 10.1002/gps.70150
Naohiro Kimura, Yoshihiro Chadani, Ryo Kawai, Ryoko Fujito, Hideki Kanemoto, Ryuichi Takahashi, Tetsuo Kashibayashi, Shunichiro Shinagawa, Kenji Tagai, Kazunari Ishii, Manabu Ikeda, Hiroaki Kazui

Objective

The association between core clinical features and anxiety and the neural basis of anxiety in patients with dementia with Lewy bodies (DLB) are unknown. Therefore, this study examined the core clinical features associated with anxiety in DLB and identified the brain regions associated with anxiety using statistical imaging analysis.

Methods

This study was conducted using a part of the data from “The Japan multicenter study: Behavioral and psychological symptoms Integrated Research in Dementia-Retrospective Neuroimaging part”. Overall, 40 patients with probable DLB whose clinical dementia rating score was either 0.5 or 1 were included in this study. Anxiety was evaluated using the Neuropsychiatric Inventory (NPI). The incidence of each of the 4 core features was compared between patients with and without anxiety, and the brain regions associated with anxiety were examined using single-photon emission computed tomography data.

Results

Patients with DLB with anxiety had a significantly higher percentage of fluctuating cognition than those without anxiety. The NPI anxiety score was significantly negatively correlated with regional cerebral blood flow in the right supramarginal gyrus in patients with DLB.

Conclusion

Anxiety in DLB is associated with fluctuating cognition. It is also likely that the brain regions associated with anxiety in DLB are potentially influenced by the neurofunctional characteristics of DLB, in which the parietal lobes are more likely to be impaired.

目的探讨路易体痴呆患者核心临床特征与焦虑的关系及焦虑的神经基础。因此,本研究考察了DLB患者与焦虑相关的核心临床特征,并利用统计成像分析确定了与焦虑相关的大脑区域。方法本研究采用“日本多中心研究:痴呆行为与心理症状综合研究-回顾性神经影像学部分”的部分数据进行。总的来说,40名临床痴呆评分为0.5或1分的可能患有DLB的患者被纳入本研究。使用神经精神量表(NPI)评估焦虑。比较焦虑患者和非焦虑患者4个核心特征的发生率,并使用单光子发射计算机断层扫描数据检查与焦虑相关的大脑区域。结果伴焦虑的DLB患者认知波动百分比明显高于无焦虑的DLB患者。DLB患者NPI焦虑评分与右侧边缘上回区域脑血流量呈显著负相关。结论DLB患者焦虑与认知波动有关。DLB患者与焦虑相关的大脑区域也可能受到DLB神经功能特征的潜在影响,其中顶叶更容易受损。
{"title":"Neural Basis of Anxiety in Dementia With Lewy Bodies","authors":"Naohiro Kimura,&nbsp;Yoshihiro Chadani,&nbsp;Ryo Kawai,&nbsp;Ryoko Fujito,&nbsp;Hideki Kanemoto,&nbsp;Ryuichi Takahashi,&nbsp;Tetsuo Kashibayashi,&nbsp;Shunichiro Shinagawa,&nbsp;Kenji Tagai,&nbsp;Kazunari Ishii,&nbsp;Manabu Ikeda,&nbsp;Hiroaki Kazui","doi":"10.1002/gps.70150","DOIUrl":"https://doi.org/10.1002/gps.70150","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The association between core clinical features and anxiety and the neural basis of anxiety in patients with dementia with Lewy bodies (DLB) are unknown. Therefore, this study examined the core clinical features associated with anxiety in DLB and identified the brain regions associated with anxiety using statistical imaging analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study was conducted using a part of the data from “The Japan multicenter study: Behavioral and psychological symptoms Integrated Research in Dementia-Retrospective Neuroimaging part”. Overall, 40 patients with probable DLB whose clinical dementia rating score was either 0.5 or 1 were included in this study. Anxiety was evaluated using the Neuropsychiatric Inventory (NPI). The incidence of each of the 4 core features was compared between patients with and without anxiety, and the brain regions associated with anxiety were examined using single-photon emission computed tomography data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patients with DLB with anxiety had a significantly higher percentage of fluctuating cognition than those without anxiety. The NPI anxiety score was significantly negatively correlated with regional cerebral blood flow in the right supramarginal gyrus in patients with DLB.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Anxiety in DLB is associated with fluctuating cognition. It is also likely that the brain regions associated with anxiety in DLB are potentially influenced by the neurofunctional characteristics of DLB, in which the parietal lobes are more likely to be impaired.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gps.70150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144934746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Most Patients Attending a Geriatrician-Led Memory Clinic are Not Eligible for Alzheimer's Disease-Modifying Drugs 大多数参加老年医生主导的记忆诊所的患者没有资格使用阿尔茨海默病治疗药物
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-02 DOI: 10.1002/gps.70149
Brendan Flanagan, Jayne Lynch, Sahil Kakar, Bernadette McGuinness, Katherine Patterson, A. Peter Passmore, Emma Louise Cunningham
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引用次数: 0
Associations Between Sleep Duration Trajectories and Depressive Symptoms Among Middle-Aged and Older Adults: Findings From a Nationally Representative Survey 中老年人睡眠持续时间轨迹与抑郁症状之间的关系:一项全国代表性调查的结果
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-02 DOI: 10.1002/gps.70154
Tingyi Jia, Changgui Kou, Yanchi Zhang, Zhouyang Sun, Qianlu Ding, Yuan Feng, Xinru Guo, Songyu Wu, Qianyi Wang, Qianlong Huang, Xiaopeng Sun, Wei Han, Wei Bai

Objectives

The relationship between sleep duration and depressive symptoms remains controversial in middle-aged and older adults. The aim of this study is to investigate the relationship of sleep duration trajectories with depressive symptoms and conduct further exploration through network analysis.

Methods

Based on the five waves of data on 8681 middle-aged and older adults from 2011 to 2020 in the China Health and Retirement Longitudinal Study database, group-based trajectory modeling was employed to depict their sleep trajectories. Binary logistic regression and network analysis were conducted to assess the relationship between sleep trajectories and depressive symptoms. Subgroup analysis was performed based on age (< 60, ≥ 60 years).

Results

The study identified three nighttime sleep duration trajectories, three daytime nap duration trajectories, and nine combined trajectories. People with initially low or moderate then decreasing nighttime sleep duration trajectory were more likely to have depressive symptoms compared with those with persistently recommended trajectory. And people with the combination of initially low then decreasing nighttime sleep and initially moderate or low then increasing daytime nap duration trajectories and the combination of initially moderate then decreasing nighttime sleep and initially high then increasing daytime nap duration trajectories were prone to have depressive symptoms compared with the combination of persistently recommended nighttime sleep and initially moderate then increasing daytime nap duration trajectories. The association between sleep trajectories and depressive symptoms may be modified by age groups (< 60 vs. ≥ 60 years). In network analyses, “felt depressed” was the most central item, and there were structural differences across different sleep duration trajectory networks.

Conclusions

Taking naps could offset the risk of depressive symptoms for people who lacked sleep at night. Developing different intervention strategies based on different sleep trajectories might help alleviate the onset of depressive symptoms.

目的在中老年人群中,睡眠时间与抑郁症状之间的关系仍存在争议。本研究旨在探讨睡眠持续时间轨迹与抑郁症状的关系,并通过网络分析进行进一步探索。方法基于2011 - 2020年中国健康与退休纵向研究数据库中8681名中老年人的5波数据,采用基于群体的轨迹建模方法对其睡眠轨迹进行刻画。采用二元逻辑回归和网络分析来评估睡眠轨迹与抑郁症状之间的关系。根据年龄(60岁,≥60岁)进行亚组分析。研究确定了三种夜间睡眠持续时间轨迹,三种白天小睡持续时间轨迹和九种组合轨迹。与那些持续推荐的睡眠轨迹相比,最初睡眠时间较低或中等然后逐渐减少的人更有可能出现抑郁症状。与坚持推荐夜间睡眠和最初适度然后白天小睡时间增加的轨迹相结合的人最初夜间睡眠时间少然后减少最初夜间睡眠时间多然后白天小睡时间增加的轨迹相结合的人更容易出现抑郁症状与坚持推荐夜间睡眠和最初适度然后白天小睡时间增加的轨迹相比较。睡眠轨迹与抑郁症状之间的关联可能因年龄组而改变(60岁vs.≥60岁)。在网络分析中,“感到抑郁”是最核心的项目,并且在不同的睡眠持续时间轨迹网络中存在结构差异。结论:小睡可以抵消夜间睡眠不足的人出现抑郁症状的风险。根据不同的睡眠轨迹制定不同的干预策略可能有助于减轻抑郁症状的发作。
{"title":"Associations Between Sleep Duration Trajectories and Depressive Symptoms Among Middle-Aged and Older Adults: Findings From a Nationally Representative Survey","authors":"Tingyi Jia,&nbsp;Changgui Kou,&nbsp;Yanchi Zhang,&nbsp;Zhouyang Sun,&nbsp;Qianlu Ding,&nbsp;Yuan Feng,&nbsp;Xinru Guo,&nbsp;Songyu Wu,&nbsp;Qianyi Wang,&nbsp;Qianlong Huang,&nbsp;Xiaopeng Sun,&nbsp;Wei Han,&nbsp;Wei Bai","doi":"10.1002/gps.70154","DOIUrl":"https://doi.org/10.1002/gps.70154","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The relationship between sleep duration and depressive symptoms remains controversial in middle-aged and older adults. The aim of this study is to investigate the relationship of sleep duration trajectories with depressive symptoms and conduct further exploration through network analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Based on the five waves of data on 8681 middle-aged and older adults from 2011 to 2020 in the China Health and Retirement Longitudinal Study database, group-based trajectory modeling was employed to depict their sleep trajectories. Binary logistic regression and network analysis were conducted to assess the relationship between sleep trajectories and depressive symptoms. Subgroup analysis was performed based on age (&lt; 60, ≥ 60 years).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study identified three nighttime sleep duration trajectories, three daytime nap duration trajectories, and nine combined trajectories. People with initially low or moderate then decreasing nighttime sleep duration trajectory were more likely to have depressive symptoms compared with those with persistently recommended trajectory. And people with the combination of initially low then decreasing nighttime sleep and initially moderate or low then increasing daytime nap duration trajectories and the combination of initially moderate then decreasing nighttime sleep and initially high then increasing daytime nap duration trajectories were prone to have depressive symptoms compared with the combination of persistently recommended nighttime sleep and initially moderate then increasing daytime nap duration trajectories. The association between sleep trajectories and depressive symptoms may be modified by age groups (&lt; 60 vs. ≥ 60 years). In network analyses, “felt depressed” was the most central item, and there were structural differences across different sleep duration trajectory networks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Taking naps could offset the risk of depressive symptoms for people who lacked sleep at night. Developing different intervention strategies based on different sleep trajectories might help alleviate the onset of depressive symptoms.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14060,"journal":{"name":"International Journal of Geriatric Psychiatry","volume":"40 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ten-Year Cognitive Trajectories and Determinants in Chinese Older Adults Without Formal Schooling: Chinese Longitudinal Healthy Longevity Survey 2008–2018 中国未接受正规教育老年人10年认知轨迹及其影响因素:2008-2018年中国健康长寿纵向调查
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-08-29 DOI: 10.1002/gps.70135
Lihui Tu, Xiaozhen Lv, Qinge Zhang

Objectives

Lack of formal schooling remains prevalent among older adults in China, particularly in rural areas. This study investigates the cognitive function trajectory and influencing factors in older adults without formal schooling from the Chinese Longitudinal Healthy Longevity Survey (CLHLS).

Methods

The study included 2159 individuals without formal schooling (NFS) and 2234 individuals with formal schooling (FS), all cognitively healthy and aged over 60 at the first observation from the 2008 - 2018 CLHLS cohort. Cognitive function was measured using the Chinese version of the Mini-Mental State Examination (MMSE). Group-based trajectory modeling was used to identify potential heterogeneity of longitudinal changes over the 10 years. Logistic regression was used to investigate associations between baseline characteristics (age, sex, marital status, functional abilities, leisure activity, and health status and behaviors) and trajectory classes.

Results

NFS individuals were generally older (80 vs. 75.3 years), more likely to be female (72.2% vs. 29.9%), unmarried (43.1% vs. 68.2%), and underweight (27.3% vs. 17.8%). They also had higher prevalence of hearing impairment (40.1% vs. 30.5%), functional limitations (39.6% vs. 19.2%), and extreme sleep length, while lower baseline cognitive function (MMSE score: 26.5 vs. 28.2). Additionally, they were less likely to engage in exercise, leisure activities, or alcohol consumption. Three trajectories (labeled stable, slow decline, and rapid decline) were identified according to the changes in MMSE scores for both groups. For the NFS group, both the slow and rapid decline groups accounted for a larger proportion (15.0% and 12.3%, respectively) than the FS decline groups (6.5% and 5.3%, respectively), and the NFS individuals had a lower baseline MMSE score with a faster decline. In the multivariable logistic regression analyses, older age, hearing impairment, poorer functional abilities, and lower baseline MMSE scores were significantly associated with cognitive decline in both groups compared to the stable group. For the NFS individuals, female sex was a risk factor for slow decline, while marital status was associated with rapid decline.

Conclusions

These findings underscore the importance of considering formal schooling status in cognitive aging research. They also emphasize the need to address educational disparities and promote social and economic well-being, particularly for vulnerable populations, to mitigate the risk of cognitive decline and

在中国,特别是在农村地区,老年人缺乏正规教育的现象仍然普遍存在。本研究通过中国健康寿命纵向调查(CLHLS)对未接受正规教育的老年人的认知功能轨迹及其影响因素进行了研究。方法纳入2008 - 2018年CLHLS队列中首次观察时认知健康且年龄在60岁以上的2159名未受过正规教育的个体(NFS)和2234名受过正规教育的个体(FS)。认知功能采用中文版的简易精神状态测验(MMSE)进行测量。使用基于组的轨迹模型来识别10年来纵向变化的潜在异质性。采用Logistic回归调查基线特征(年龄、性别、婚姻状况、功能能力、休闲活动、健康状况和行为)与轨迹类别之间的关系。结果NFS患者普遍年龄较大(80岁vs. 75.3岁),女性居多(72.2% vs. 29.9%),未婚(43.1% vs. 68.2%),体重过轻(27.3% vs. 17.8%)。他们也有更高的听力障碍患病率(40.1%对30.5%),功能限制(39.6%对19.2%)和极端睡眠时间,而较低的基线认知功能(MMSE评分:26.5对28.2)。此外,他们不太可能从事运动、休闲活动或饮酒。根据两组MMSE评分的变化,确定了三种轨迹(标记为稳定、缓慢下降和快速下降)。对于NFS组,缓慢和快速下降组所占的比例(分别为15.0%和12.3%)都大于FS下降组(分别为6.5%和5.3%),并且NFS个体的基线MMSE评分较低,下降速度较快。在多变量logistic回归分析中,与稳定组相比,年龄较大、听力障碍、较差的功能能力和较低的基线MMSE评分与两组的认知能力下降显著相关。对于NFS个体,女性性别是缓慢下降的危险因素,而婚姻状况与快速下降有关。结论这些发现强调了在认知衰老研究中考虑正规教育的重要性。他们还强调需要解决教育差距问题,促进社会和经济福祉,特别是弱势群体的福祉,以减轻认知能力下降和痴呆症的风险。
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引用次数: 0
Barthel Index Score at Admission to Predict 1-Month and 1-Year Prognosis in Inpatients Aged ≥ 75 Years With Multimorbidity 入院时Barthel指数评分预测≥75岁多病住院患者1个月和1年预后
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-08-28 DOI: 10.1002/gps.70147
Xin Chen, Chen-lu Zhang, Hua Jiang

Objective

To investigate the Barthel Index (BI) score in predicting the 1-month and 1-year prognosis after discharge.

Methods

This was a retrospective observational single-center study. We retrospectively enrolled consecutive inpatients aged ≥ 75 years from a large public hospital. Information of the basic demographic variables, BI score, disease burden, length of hospital stay, medical cost and outcomes of patients were collected. Then we analyzed the association between BI score and clinical outcomes.

Results

A total of 242 subjects were included in this study. The median of BI score was 40 (5, 70). There were 48.76% and 82.23% patients with poor prognosis within 1 month and 1 year after discharge. BI remained an independent predictor of poor outcome within 1 month (P < 0.001) and 1 year (P = 0.027) after adjusting other factors. BI score was negatively correlated with poor outcomes. The calibration of 1-year outcomes was better than that of 1-month outcomes. The ROC analysis showed the AUC of the BI in predicting 1-month and 1-year outcomes were 0.860(P < 0.001) and 0.674(P < 0.001) respectively. The cutoff values for BI to predict 1-month and 1-year outcomes were 42.5 and 52.5.

Conclusions

The BI score at admission was an useful predictor of outcomes within 1 month and 1 year after discharge for very elderly multimorbidity inpatients.

目的探讨Barthel指数(BI)评分对患者出院后1个月及1年预后的预测价值。方法回顾性观察性单中心研究。我们回顾性地纳入了一家大型公立医院年龄≥75岁的连续住院患者。收集患者基本人口学变量、BI评分、疾病负担、住院时间、医疗费用和转归等信息。然后我们分析了BI评分与临床结果之间的关系。结果本研究共纳入242名受试者。BI评分中位数为40(5,70)。出院后1个月和1年内预后不良的患者分别为48.76%和82.23%。在调整其他因素后,BI仍然是1个月内(P < 0.001)和1年内(P = 0.027)不良预后的独立预测因子。BI评分与预后不良呈负相关。1年预后的校正优于1个月预后的校正。ROC分析显示BI预测1个月和1年预后的AUC分别为0.860(P < 0.001)和0.674(P < 0.001)。BI预测1个月和1年预后的临界值分别为42.5和52.5。结论入院时的BI评分是预测高龄多病住院患者出院后1个月和1年预后的有效指标。
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引用次数: 0
Correction to “Accuracy of the Short-Form Montreal Cognitive Assessment: Systematic Review and Validation” 对“短格式蒙特利尔认知评估的准确性:系统回顾和验证”的更正
IF 2.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Pub Date : 2025-08-25 DOI: 10.1002/gps.70146

J. A. McDicken, E. Elliott, G. Blayney, S. Makin, M. Ali, A. J. Larner, T. J. Quinn, VISTA-Cognition Collaborators. “Accuracy of the Short-Form Montreal Cognitive Assessment: Systematic Review and Validation,” International Journal of Geriatric Psychiatry 34, no. 10 (October 2019): 1515–1525, https://doi.org/10.1002/gps.5162.

There are no changes required to the conclusions. We apologize for this error.

Updated Figure 2

J. A. McDicken, E. Elliott, G. Blayney, S. Makin, M. Ali, A. J. Larner, T. J. Quinn, vista -认知合作者。“短格式蒙特利尔认知评估的准确性:系统回顾和验证”,《国际老年精神病学杂志》34期,第2期。10(2019年10月):1515-1525,https://doi.org/10.1002/gps.5162.There结论无需更改。我们为这个错误道歉。更新后的图2
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引用次数: 0
期刊
International Journal of Geriatric Psychiatry
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