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A Case Report of Lumbosacral Lipomyelomeningocele with Tethered Cord Syndrome 腰骶部脂肪性脊膜膨出伴脊髓栓系综合征1例
Pub Date : 2022-12-20 DOI: 10.32553/ijmsdr.v6i12.961
Deepak Mewara, Rajveer Singh, Vartika Jain, Ajay Kumar, Abhishek Kr. Gupta
The objective is to describe a rare case of lumbosacral lipomyelomeningocele with Tethered Cord Syndrome. Tethered cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of spinal cord within the spinal column. A 7 years old girl child presented with lumbosacral swelling with non healing ulcer on foot and with weakness of lower limbs since childhood. MRI scan of lumbosacral spine suggest spinal dysraphism in L3-L5 vertebrae with lipomeningomyelocele from L2 to S2 levels with tethered low lying cord .The patient underwent  surgical procedure. The majority cases of tethered cord syndrome are related to spinal dysraphism.Children with spinal dysraphism, especially those with lipomyelomeningocele, who may be associated with TCS, which may be asymptomatic at an early stage, require intensive follow-up care and observation. Keyword: Spinal dysraphism, neurological disorder, TCS, lipomeningomyelocele.
目的是描述一个罕见的腰骶部脂肪性脊膜膨出伴脊髓栓系综合征的病例。脊髓栓系综合征是一种神经系统疾病,由组织附着物引起,限制脊髓在脊柱内的运动。一名7岁女童,自幼表现为腰骶部肿胀伴足部溃疡不愈合,下肢无力。腰骶椎MRI扫描提示L3-L5椎体脊柱异常,伴L2至S2水平的脂肪性脊髓膨出,伴低位脊髓栓系。脊髓栓系综合征的大多数病例与脊柱发育异常有关。脊柱发育异常的儿童,特别是那些可能与TCS相关的脂质脊髓脊膜膨出的儿童,在早期可能无症状,需要加强随访和观察。关键词:脊柱发育异常,神经系统疾病,TCS,脂肪现象脊髓膨出。
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引用次数: 0
Medical Student’s Perception of Diagnostic Surgical Pathology Course: Necessities, Difficulties and Solutions 医学生对外科病理诊断课程的认识:必要性、难点与对策
Pub Date : 2022-11-26 DOI: 10.32553/ijmsdr.v6i11.959
A. Agarwal, Syed Sajid Hussain Shah, A. Syed, A. M. Alrawaili, Ghadah Khalid H. Alanazi, M. K. AlZalbani
Background: Students’ perceptions and feedback have a significant impact on academic progress. The aim of this study was to determine the perceptions of medical students regarding the surgical pathology course taken by medical students at Northern Border University. Material and methods: In this cross-sectional study, a questionnaire was given to medical students taking this course. The questionnaire comprised several items on students’ attitudes toward surgical pathology. And a five-point Likert scale was used. Data were analysed using Statistical Package for the Social Science (SPSS) v 20 software. Results: One hundred and fifty three questionnaires received from the students were analysed.   Discussion and Conclusions: The answers to the questionnaire showed that ‘one size fits all’ approach cannot be employed for educating the students. A combination of different strategies and methods helped improve student satisfaction, particularly in regard with case presentation studies and practical’s. New strategies were adopted not just for improving academic performance but keeping in mind future clinical practice, enhancing students’ understanding and knowledge retention abilities. Key words: medical student’s, perception , diagnostic surgical pathology course: necessities, difficulties and solutions.
背景:学生的认知和反馈对学业进步有显著的影响。本研究的目的是了解医学生对北边境大学医学生所修的外科病理学课程的看法。材料与方法:本研究采用横断面调查法,对修习本课程的医学生进行问卷调查。问卷内容包括学生对外科病理的态度。采用李克特五点量表。使用SPSS v20软件对数据进行分析。结果:对收到的153份学生问卷进行了分析。讨论与结论:调查问卷的答案表明,“一刀切”的方法不能用于教育学生。不同策略和方法的结合有助于提高学生的满意度,特别是在案例展示研究和实践方面。采用新的策略不仅是为了提高学习成绩,也是为了考虑未来的临床实践,提高学生的理解和知识记忆能力。关键词:医学生;感知;外科病理诊断课程;
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引用次数: 0
A Study of Cyclin D1, E-cadherin, EGFR, HER- 2, Ki67, and p53 Tumor Marker Expressions in Neoplastic and Non -neoplastic Gall Bladder Lesions and their Clinico-pathological Correlation 肿瘤与非肿瘤性胆囊病变中Cyclin D1、E-cadherin、EGFR、HER- 2、Ki67、p53肿瘤标志物表达及其临床病理相关性的研究
Pub Date : 2022-11-26 DOI: 10.32553/ijmsdr.v6i11.958
A. Agarwal, R. Bansal, Mamta Gupta
Background: Worldwide gall bladder cancer (GBC) is known to be the commonest malignant tumour of the biliary tract. It is the most aggressive carcinoma of the biliary tract with short median survival from the time of diagnosis. The aggressive biologic behaviour of the carcinoma and non-availability of sensitive screening tests for early detection may be responsible for the poor prognosis associated with GBC. Material and Methods: Patients diagnosed with neoplastic and non-neoplastic gallbladder lesions in the Department of Pathology, Subharti Medical College in India were included in the study. Gall bladder biopsies findings and the clinic-pathological data were compiled and different immune-markers  diagnostic and therapeutic usefulness were studied . Results: 24 (24.0%) of the cases were in the age group of 51-60 Years.  In 38 (38.0%) of the cases the site of lesion was Fundus. 55 (55.0%) of cases had associated stones. 36 (36.0%) of them had P53: strong over expression, 40 (40.0%) of the them had ki67: strong over expression, 25 (25.0%) had EGFR: strong over expression whereas negative expression for  Her2/Neu was found in 61 (61.0%) of the cases. Cyclin D1: moderate over expression was found in 27 (27.0%) of them and moderate over expression of E-cadherin were found in  22 (23.2%) cases. Conclusions: Novel prognostic biomarkers could bring about the needed breakthrough in gall bladder cancer diagnosis and treatment. We conclude that the biomarkers studied by us  may help in the identification of cases who may benefit tremendously from adjuvant and targeted therapies. Key words: Cyclin D1, E-cadherin, EGFR, HER- 2, Ki67,  p53, tumour marker, neoplastic , non –neoplastic, Gall bladder lesions.
背景:在世界范围内,胆囊癌(GBC)是胆道最常见的恶性肿瘤。它是最具侵袭性的胆道癌,自诊断以来中位生存期较短。癌的侵袭性生物学行为和缺乏早期发现的敏感筛查试验可能是导致GBC预后不良的原因。材料和方法:纳入印度Subharti医学院病理科诊断为肿瘤和非肿瘤胆囊病变的患者。收集胆囊活检结果和临床病理资料,研究不同免疫标记物的诊断和治疗价值。结果:51 ~ 60岁年龄组24例(24.0%)。38例(38.0%)病变部位为眼底,55例(55.0%)合并结石。其中P53强过表达36例(36.0%),ki67强过表达40例(40.0%),EGFR强过表达25例(25.0%),Her2/Neu阴性61例(61.0%)。Cyclin D1:中度过表达27例(27.0%),E-cadherin中度过表达22例(23.2%)。结论:新的预后生物标志物有望为胆囊癌的诊断和治疗带来必要的突破。我们的结论是,我们研究的生物标志物可能有助于识别可能从辅助和靶向治疗中获益的病例。关键词:Cyclin D1, E-cadherin, EGFR, HER- 2, Ki67, p53,肿瘤标志物,肿瘤性,非肿瘤性,胆囊病变
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引用次数: 0
The Study of Predictive Factors in the Contribution and Progression of Coronary Artery Disease: A Hospital Based Cross Sectional Study 冠状动脉疾病贡献和进展的预测因素研究:基于医院的横断面研究
Pub Date : 2022-11-19 DOI: 10.32553/ijmsdr.v6i11.957
Anil Saini
Coronary Artery Disease is an insidious disease which can present clinically with sudden onset of Symptoms that necessitate hospitalization and life saving intervention. The spectrum of clinicopathological entities can range from Stable Angina, Untable Angina and Acute Coronary Syndrome. The last but not the  least entity is life threatening condition with significant Morbidity and Mortality unless timely treatment is given. There are many factors which can initiate and lead to development of the disease. The Aim of this study is to identify the Risk Factors in the causation of the coronary artery disease  and there by reinforce the Knowledge of Medical Fraternity about the conditions which can predict coronary artery disease, especially Acute Coronary Syndrome[Unstable Angina ,Myocardial Infarction]. Key Words: Variable, Study, Coronary Artery Disease, Prediction, Atherosclerosis.
冠状动脉疾病是一种隐匿性疾病,临床表现为突发性症状,需要住院治疗和采取挽救生命的干预措施。临床病理实体的范围可以从稳定型心绞痛,不稳定型心绞痛和急性冠脉综合征。最后但并非最不重要的实体是危及生命的条件具有显著的发病率和死亡率,除非及时给予治疗。有许多因素可以引发和导致疾病的发展。本研究的目的是确定导致冠状动脉疾病的危险因素,并通过加强医学兄弟对可预测冠状动脉疾病,特别是急性冠状动脉综合征[不稳定心绞痛,心肌梗死]的条件的认识。关键词:变量,研究,冠心病,预测,动脉粥样硬化
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引用次数: 0
MRI Imaging of Dumbbell Shaped Intra Dural Extramedullary Spinal Schwannoma 哑铃形硬膜内髓外脊髓神经鞘瘤的MRI表现
Pub Date : 2022-10-30 DOI: 10.14445/23939117/ijms-v9i5p102
Anju Dhiman, P. Chandna, D. S. Dhiman, M. Abdullah
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引用次数: 0
HRCT Imaging of Pulmonary Tuberculosis 肺结核的HRCT成像
Pub Date : 2022-10-30 DOI: 10.14445/23939117/ijms-v9i5p101
P. Chandna, A. Dhiman, D. S. Dhiman
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引用次数: 0
The Modified NICH (Nigam’s Inverted Curtain Hernioplasty) for Inguinal hernia – A foolproof Procedure for Recurrence 改良的niich (Nigam的倒置帷幕疝成形术)治疗腹股沟疝-复发的万无一失的程序
Pub Date : 2022-10-15 DOI: 10.32553/ijmsdr.v6i10.953
V. Nigam, Siddhartha Nigam
It is a procedure where NICH is modified with basic repair, 2 stitches approximating inguinal ligament with conjoint tendon. Hundred patients were operated between April 2012 to April 2022 by modified NICH technique. All were primary uncomplicated cases of inguinal hernia. Modified NICH procedure for inguinal hernia takes care of recurrence better than any other procedure for inguinal hernia. Though NICH is a good modification of tension - free Lichtenstein procedure for inguinal hernia but modified NICH further improves the results specialty the recurrence. Modified NICH hernioplasty gives added advantages of repairing posterior inguinal wall which directly influences the recurrence rate. In our series of 100 cases no post – operative recurrence was noted. Though the series described here is small so more cases and more time is required to further confirm the results. Key words: Hernioplasty, Inguinal hernia, Modified NICH, NICH, Recurrence.
这是一种对NICH进行基本修复的手术,用2针接近腹股沟韧带和联合肌腱。2012年4月至2022年4月,100例患者采用改良的NICH技术进行手术。所有病例均为原发性无并发症腹股沟疝。改良的NICH手术治疗腹股沟疝比任何其他手术治疗腹股沟疝的复发更好。虽然NICH是一种改良的无张力利希滕斯坦手术治疗腹股沟疝的好方法,但改良后的NICH进一步改善了治疗效果,特别是复发。改良疝修补术对修补腹股沟后壁有额外的优势,直接影响复发率。在我们的100例病例中,没有发现术后复发。虽然这里描述的系列很小,因此需要更多的病例和更多的时间来进一步确认结果。关键词:疝成形术,腹股沟疝,改良疝修补术,疝修补术,复发。
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引用次数: 0
Covid-19 Vaccination Drive Among Dental Students: A Sweet and A Sour Encounter 牙科学生的Covid-19疫苗接种活动:甜蜜和苦涩的相遇
Pub Date : 2022-09-22 DOI: 10.32553/ijmsdr.v6i9.951
Parul Sharma, Navneet Kour, Ametesh
Since 1918 flu pandemic, novel human corona virus diseases has been documented as the fifth pandemic resulting in catastrophic events not only in terms of deaths and increased number of cases but also hampered the workplaces. Dental practitioners, due to the concise area of work are in direct contact and consequently at a higher risk for transmitting or acquiring this diseases. In this COVID era, vaccine hesitancy remains a greater barrier to the population inoculation against this highly dreadful and infectious disease. With the rapid development of the vaccine globally, major concerns about it acceptance and safety still remains a question. Thus the main Aim of our article was to assess the acceptance and hesitancy rates regarding COVID-19 vaccination among dental student, exploring their experience and creating an awareness program for counseling of hesitant subjects. Material and Methodology: randomized 100 under and post graduate dental students of Himachal Pradesh were selected and divided into two groups G1 with 50 vaccinated and G2 with 50 non vaccinated students. A well structured, online multiple choice questionnaire was formulated and distributed among them for recording the response. The data obtained was collected, tabulated and analyzed using Chi square test for the experience of subjects regarding vaccine. Results: when compared around 76% of the vaccinated respondents agreed about the fact of making vaccination mandatory for all while 90% of the non-vaccinated respondents were still confused about the same. Conclusion:  the results of our study highlighted for the need and awareness about the safety and effectiveness to promote the uptake of COVID-19 vaccine. Though made obligatory, there are still a huge number of people who still raise a question regarding the efficacy of the vaccine.  Keywords: Acceptance, Covid-19, Dentist, Hesitancy, Vaccine, Virus.
自1918年流感大流行以来,新型人类冠状病毒病已被记录为第五次大流行,不仅在死亡和病例数量增加方面造成灾难性事件,而且妨碍了工作场所。牙科从业人员由于工作领域简明扼要,直接接触疾病,因此传播或获得这种疾病的风险较高。在这个COVID时代,疫苗犹豫仍然是人口接种这一高度可怕和传染性疾病的更大障碍。随着该疫苗在全球的快速发展,对其接受度和安全性的主要担忧仍然是一个问题。因此,我们文章的主要目的是评估牙科学生对COVID-19疫苗接种的接受率和犹豫率,探索他们的经历,并创建一个犹豫受试者的咨询意识计划。材料与方法:随机选择喜马偕尔邦牙科专业本科生和研究生100名,分为两组,G1组50名接种疫苗,G2组50名未接种疫苗。制定了一份结构良好的在线选择问卷,并分发给他们,以记录他们的反应。收集获得的数据,制作表格,并使用卡方检验对受试者关于疫苗的经验进行分析。结果:相比之下,约76%的接种疫苗的受访者同意强制所有人接种疫苗的事实,而90%的未接种疫苗的受访者仍然对此感到困惑。结论:我们的研究结果强调了促进COVID-19疫苗摄取的必要性和安全性和有效性意识。虽然是强制性的,但仍然有很多人对疫苗的有效性提出质疑。关键词:接受,Covid-19,牙医,犹豫,疫苗,病毒
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引用次数: 0
A Review on Helicobacter pylori Infection 幽门螺杆菌感染研究进展
Pub Date : 2022-09-17 DOI: 10.32553/ijmsdr.v6i9.950
M. Maity, Mamta Naagar
Helicobacter pylori (H. pylori) was first identified in 1982 by the Australian physicians Barry Marshall and Robin Warren. Helicobacter pylori is also known as Campylobacter pylori. It is a gram-negative, micro-aerophilic, spiral (helical) bacterium usually found in the stomach. H. pylori infection is one of the most common and chronic bacterial infection, affecting approximately half of the world's population. Peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma and gastric cancer all are linked to H. pylori. There are various diagnostic procedures to detect H. pylori infection and the choice of one approach over another is based on a number of considerations including accessibility, benefits and drawbacks of each method, cost, and the age of the patients. When H. pylori infection is diagnosed, doctor determines the therapy on the basis of patient's clinical status. Generally, eradication of H. pylori is recommended for treatment and prevention of the infection. In most of the cases H. pylori infections are cured with triple therapy. Moreover, quadruple therapies, sequential therapies and concomitant therapies have been developed as major alternative options to treat H. pylori infection. In this review pathophysiology, prevalence, transmission, clinical sign & symptoms, risk factors, and diagnostic techniques used to detect H. pylori infection as well as H. pylori eradication therapy regimens are discussed. Keywords: Diagnosis, Helicobacter pylori, Treatment, Hybrid therapy, Concomitant therapy, Sequential therapy
1982年,澳大利亚医生巴里·马歇尔和罗宾·沃伦首次发现了幽门螺杆菌。幽门螺杆菌也被称为幽门弯曲杆菌。它是一种革兰氏阴性、嗜气微的螺旋状细菌,通常在胃中发现。幽门螺杆菌感染是最常见的慢性细菌感染之一,影响着世界上大约一半的人口。消化性溃疡、胃溃疡、粘膜相关淋巴组织淋巴瘤和胃癌都与幽门螺杆菌有关。检测幽门螺杆菌感染有多种诊断方法,选择一种方法而不是另一种方法是基于许多考虑因素,包括可及性、每种方法的优缺点、成本和患者的年龄。当诊断为幽门螺旋杆菌感染时,医生根据患者的临床情况确定治疗方案。一般来说,根除幽门螺杆菌被推荐用于治疗和预防感染。在大多数情况下,幽门螺杆菌感染可以通过三联疗法治愈。此外,四联疗法、序贯疗法和伴随疗法已成为治疗幽门螺杆菌感染的主要替代方案。本文就幽门螺杆菌的病理生理、流行、传播、临床体征和症状、危险因素、检测幽门螺杆菌感染的诊断技术以及根除幽门螺杆菌的治疗方案进行了讨论。关键词:诊断,幽门螺杆菌,治疗,混合治疗,联合治疗,序贯治疗
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引用次数: 2
Comparison of Janda’s Muscle Energy Technique Vs Myofascial Release of Hamstrings on Back Range of Motion and Dysfunction in Adolescent girls with Nonspecific Low Back Pain 简达肌能量法与腘绳肌筋膜松解对青春期少女非特异性腰痛背部活动范围和功能障碍的影响比较
Pub Date : 2022-09-09 DOI: 10.32553/ijmsdr.v6i9.949
Anjali Choudhary, Jaspreet Kaur
Background: Nonspecific Low Back Pain among the adolescent  girls is due to underlying predisposing factors like postural errors, lack of physical exercise in which Hamstrings tightness is a key contributing factor. Methodology: The research was experimental in nature. The subjects was selected through purposive sampling. 60 female collegiate girls was selected and divided into 3 groups. Group A include 20 subjects was given conventional treatment as Hot Pack on Hamstrings Muscle over the posterior aspect of thigh of both the lower limbs for 10 minutes. Then Lumbar Mobility Exercises was performed by subject. Group B include 20 subjects was given conventional treatment as Hot Pack on Hamstrings Muscle over the posterior aspect of thigh of both the lower limbs for 10 minutes. Then Lumbar Mobility Exercises was performed by subject. Group C  include 20 subjects was given  conventional treatment as Hot Pack on Hamstrings Muscle over the posterior aspect of thigh of both the lower limbs for 10 minutes. Then Lumbar Mobility Exercises was performed by subject. Pretest and Post test data for both the groups will be evaluated for Back Pain using Visual Analogue Scale and Back Dysfunction using Oswestry Low Back Pain Disability Questionnaire respectively. Result: The data was analysed by using paired and unpaired t-test. There were Significant differences in pre and post scores of Group B (MET) and Group C (MFR) when paired t-test was applied. When these groups were compared using unpaired t-test, all showed significant differences. Group B (MET) demonstrated more improvement than Group C (MFR) and Group A (control). However, Group C (MFR) showed significant improvement than Group A (control). Conclusion: The study concluded that Muscle Energy Technique is better than Myofascial Release Technique in improving Back Range of Motion and Dysfunction among Adolescent Girls with Nonspecific Low Back Pain. There was a significant variation of values between the Muscle Energy Technique and Myofascial Release Keywords: janda’s muscle energy technique; myofascial release; hamstrings; adolescent girls; nonspecific low back pain
背景:青春期女孩的非特异性腰痛是由于潜在的易感因素,如姿势错误,缺乏体育锻炼,其中腘绳肌紧绷是一个关键因素。方法:本研究为实验性研究。采用有目的抽样的方法选择研究对象。选取60名女大学生,分为3组。A组20例患者给予双下肢大腿后侧腘绳肌热敷常规治疗10分钟。然后进行腰椎活动训练。B组20例,给予双下肢大腿后侧腘绳肌热敷常规治疗10分钟。然后进行腰椎活动训练。C组20例患者给予双下肢大腿后侧腘绳肌热敷常规治疗10分钟。然后进行腰椎活动训练。两组的测试前和测试后数据将分别使用视觉模拟量表和Oswestry腰痛残疾问卷评估背部疼痛和背部功能障碍。结果:采用配对和非配对t检验对数据进行分析。采用配对t检验,B组(MET)和C组(MFR)的前后评分差异有统计学意义。当这些组使用非配对t检验进行比较时,均显示出显著差异。B组(MET组)比C组(MFR组)和A组(对照组)改善更多。而C组(MFR)较A组(对照组)有明显改善。结论:肌能技术在改善青春期少女非特异性腰痛的背部活动度和功能障碍方面优于肌筋膜释放技术。肌能法与肌筋膜释放法的数值差异有统计学意义肌筋膜释放;腿筋;少女;非特异性腰痛
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引用次数: 0
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International Journal of Medical Science And Diagnosis Research
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