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Evolution of COVID-19-related olfactory disorders: A systematic review and meta-analysis covid -19相关嗅觉障碍的演变:系统综述和荟萃分析
Pub Date : 2022-10-01 DOI: 10.4103/ijmh.ijmh_42_22
F. Orji, J. Akpeh, Nekwu E. Okolugbo, E. Chime
Recently acquired olfactory dysfunction (OD) has emerged as one of the hallmark manifestations of the novel coronavirus disease (COVID-19), but the evolution of its spontaneous recovery has remained inconclusive, with reports of persistence of OD beyond 6 months of onset. We undertook this systematic review and meta-analysis with a view of generating a pooled recovery rate of COVID-19-associated ODs and attempt to examine the predictors of olfactory recovery. A systematic search of Scopus, Google Scholar, and PubMed databases, comprising all longitudinal studies reporting the trajectory of COVID-19-related OD, was carried out. The pooled recovery rate was estimated with random-effects model, and the potential heterogeneity of the subgroup sources was analyzed using a meta-regression test. After the Preferred Reporting Items for Systematic Reviews and Meta-Analysis selection process, 28 studies from 16 countries were included, with a total of 5,175 OD patients, among 11,948 COVID-19 cases. The estimated global pooled recovery rate of OD was 82.7% (95% confidence interval, 77.46–88.04%), with a pooled median duration of OD of 11.6 days. Only 2 out of 28 studies had recovery data beyond a period of 2 months. But no significant difference was found in the recovery rate regarding the length of follow-up (P = 0.840). Studies that conducted objective olfactory assessments showed a significantly higher recovery rate than those with subjective assessments (P = 0.001). Although 10 studies (36%) reported >90% recovery, 9 studies (32%) documented persistence of OD in >25% of their patients. Five out of six studies showed that hyposnia tended to show complete recovery than anosmia. Age, co-morbidities, and intranasal treatments had no effects. Test of homogeneity between subgroups using Cochran’s Q test was not significant (Q = 0.69, P = 0.40). Our meta-analysis revealed high rates of early- and medium-term recovery of COVID-19-related OD. However, it also showed disturbing rates of persistence of OD. Anosmia tended to be predictive of residual OD than hyposmia. Age, comorbidities, intranasal corticosteroid, and decongestants had no effects on OD recovery.
最近获得性嗅觉功能障碍(OD)已成为新型冠状病毒病(COVID-19)的标志性表现之一,但其自发恢复的演变仍不确定,有报道称OD持续超过6个月发病。我们进行了这项系统综述和荟萃分析,以期得出与covid -19相关的ODs的综合回收率,并试图检查嗅觉恢复的预测因素。系统检索了Scopus、Google Scholar和PubMed数据库,包括报告covid -19相关OD轨迹的所有纵向研究。采用随机效应模型估计合并回收率,并采用meta回归检验分析亚组源的潜在异质性。在系统评价和荟萃分析的首选报告项目选择过程之后,来自16个国家的28项研究被纳入,在11948例COVID-19病例中,共有5175例吸毒过量患者。估计OD的总体合并回收率为82.7%(95%置信区间为77.46 ~ 88.04%),合并中位OD持续时间为11.6 d。28项研究中只有2项有超过2个月的恢复数据。两组患者的康复率随随访时间的延长无显著差异(P = 0.840)。进行客观嗅觉评估的研究显示,回收率明显高于主观评估(P = 0.001)。虽然10项研究(36%)报告了>90%的恢复,但9项研究(32%)记录了>25%的患者持续服用过量。六分之五的研究表明,睡眠不足比嗅觉缺失更容易完全恢复。年龄、合并症和鼻内治疗没有影响。Cochran’s Q检验各组间同质性差异无统计学意义(Q = 0.69, P = 0.40)。我们的荟萃分析显示,covid -19相关OD的早期和中期恢复率很高。然而,它也显示了令人不安的吸毒过量持续率。嗅觉缺失倾向于预测残留的OD而不是低氧。年龄、合并症、鼻内皮质类固醇和减充血剂对OD恢复没有影响。
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引用次数: 0
Prevalence, Pattern and Sociodemographic Correlates of Psychosocial Disorders in Obese Adolescents in Enugu, Nigeria 尼日利亚埃努古肥胖青少年心理社会障碍的患病率、模式和社会人口学相关性
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_40_21
Okechukwu Ozoalor, A. Ikefuna, A. Aronu, N. Ojinnaka
Background: Adolescent obesity is a serious public health issue. Inconsistent findings on its association with mental health problems are reported. Objective: This study aimed to determine the prevalence, pattern, and sociodemographic correlates of psychosocial disorders among obese adolescents in Enugu metropolis, Nigeria. Materials and Methods: A cross-sectional study was conducted over a 5-month period in 16 secondary schools in Enugu, Nigeria. A multi-staged systematic sampling technique was used to select participating schools. A total of 4364 adolescents aged 10–19 years from these schools were screened for obesity by measuring their height and weight, and calculating their body mass indices (BMIs), which were plotted on the Centers for Disease Control and Prevention BMI percentile chart. Seventy-four obese students were identified, and from their respective class registers, systematic sampling scheme was applied in selection of equal number of apparently healthy normal BMI (5th–84th percentile) controls matched for age and sex. The youth version of the Pediatric Symptom Checklist was used to screen for psychosocial disorder in the study participants. Results: The prevalence of psychosocial disorder was 17.6% and 12.2% among the obese and control adolescents, respectively (P = 0.02). Attention and externalizing problems were the highest among the obese adolescents, whereas psychosocial disorders were more in females than males (28.1% vs 9.5%; χ2 = 4.34, P = 0.04). Conclusion: Obese adolescents have a higher prevalence of psychosocial disorder compared to controls, with attention and externalizing problems being most common, and this was influenced by gender. Periodic assessment of the mental health of obese adolescents is advocated.
背景:青少年肥胖是一个严重的公共卫生问题。关于其与精神健康问题的关系,报告的结果不一致。目的:本研究旨在确定尼日利亚埃努古大都市区肥胖青少年中心理社会障碍的患病率、模式和社会人口学相关因素。材料和方法:在尼日利亚埃努古的16所中学进行了为期5个月的横断面研究。采用多阶段系统抽样技术选择参与学校。共有4364名来自这些学校的10-19岁的青少年通过测量他们的身高和体重,并计算他们的身体质量指数(BMI)来筛查肥胖,这些指数被绘制在疾病控制和预防中心的BMI百分位数图表上。从74名肥胖学生的班级登记簿中,采用系统抽样的方法,选择年龄、性别相匹配的表面健康正常BMI(第5 ~ 84百分位)对照者。青少年版儿科症状检查表用于筛选研究参与者的心理社会障碍。结果:肥胖青少年和正常青少年的心理社会障碍患病率分别为17.6%和12.2% (P = 0.02)。注意和外化问题在肥胖青少年中最高,而心理社会障碍在女性中多于男性(28.1%比9.5%;χ2 = 4.34, p = 0.04)。结论:与对照组相比,肥胖青少年的社会心理障碍患病率更高,其中注意力和外化问题最为常见,且受性别影响。提倡对肥胖青少年的心理健康进行定期评估。
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引用次数: 0
Predictors of knowledge of cervical cancer screening among pregnant women attending antenatal clinic in Enugu, Nigeria 尼日利亚埃努古产前诊所孕妇宫颈癌筛查知识的预测因素
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_12_22
Chidiebere J. Otti, E. Izuka, C. Obiora-Izuka, Okechukwu Ifebi, L. Ikeako, U. Nwagha
Background: One per cent of women diagnosed with cervical cancer are pregnant or postpartum at the time of diagnosis. Therefore, awareness during pregnancy is of utmost significance. Objective: To determine predictors of knowledge of cervical cancer screening among pregnant women who attended antenatal clinics in Enugu, Nigeria. Materials and Methods: It was a descriptive cross-sectional study of 419 pregnant women who attended antenatal care at the University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu (139) and the Mother of Christ Specialist Hospital, Enugu (280). A multistage random sampling method was used to select the study centres and the participants. The questionnaires were administered by the interviewers and the data collected included sociodemographic characteristics, knowledge, and practice of cervical cancer screening. Data were analyzed using SPSS version 23. Results: The mean age of the participants was 28.86 ± 5.69, Christians (92.7%), and married (82.5%). Most of the respondents (82.3%) heard about cervical cancer screening methods through their gynecologists and of the 198 respondents who have heard about cervical cancer screening, 151 (76.3%) knew about Pap smear. One hundred thirty-eight (69.7%) of the participants believe that screening for premalignant lesions of the cervix can be performed during pregnancy. Only 37.9% of the participants had ever done Pap’s smear in the past 3 years. Respondents with higher social status (Civil/Public servants) were 10 times more likely to know about cervical cancer screening than those with lower social status (Trader/farmer/artisan) (P = 0.027, OR = 9.957, 95% CI = 1.301 – 76.191). Conclusion: Higher social status is more predictive of knowledge of cervical cancer screening amongst pregnant women attending antenatal clinics. Gynaecologist disseminate the information on cervical cancer screening more and Pap’s smear remain the main screening modality known to pregnant women. Efforts should be made by other health workers and the media to disseminate appropriate information on screening modalities for the prevention of cervical cancer
背景:诊断为宫颈癌的妇女中有1%在诊断时怀孕或产后。因此,怀孕期间的意识是至关重要的。目的:确定在尼日利亚埃努古参加产前诊所的孕妇中宫颈癌筛查知识的预测因素。材料和方法:这是一项描述性横断面研究,对在埃努古伊图库-奥扎拉尼日利亚大学教学医院(139人)和埃努古基督之母专科医院(280人)接受产前护理的419名孕妇进行了研究。采用多阶段随机抽样的方法选择研究中心和研究对象。问卷由采访者填写,收集的数据包括社会人口学特征、宫颈癌筛查的知识和实践。数据分析采用SPSS version 23。结果:参与者平均年龄28.86±5.69岁,基督徒占92.7%,已婚占82.5%。大部分受访者(82.3%)曾透过妇科医生了解子宫颈癌筛查方法,而在198名曾听说子宫颈癌筛查的受访者中,151名(76.3%)曾了解子宫颈抹片检查。138(69.7%)的参与者认为宫颈癌前病变的筛查可以在怀孕期间进行。只有37.9%的参与者在过去3年内曾做过子宫颈抹片检查。社会地位较高的被调查者(公务员/公务员)对宫颈癌筛查的了解程度是社会地位较低的被调查者(商人/农民/工匠)的10倍(P = 0.027, OR = 9.957, 95% CI = 1.301 ~ 76.191)。结论:较高的社会地位对到产前诊所就诊的孕妇对宫颈癌筛查的了解程度有较高的预测作用。妇科医生更多地宣传子宫颈癌检查的资料,而子宫颈抹片检查仍然是孕妇所知的主要检查方式。其他保健工作者和媒体应努力传播关于预防宫颈癌的筛查方式的适当信息
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引用次数: 0
Evaluation of prostate-specific antigen testing: An empirical survey of laboratories in Nigerian tertiary care centers 评估前列腺特异性抗原检测:在尼日利亚三级护理中心实验室的实证调查
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_8_22
I. Meka, C. Okwor, Ekene Arum, Michael I. Ogamba, B. Omotowo, O. Kanu
Background: Prostate-specific antigen (PSA) testing has been recommended for prostate cancer screening by the World Health Organization. The combined use of total and free PSA and digital rectal examination is said to improve the sensitivity and specificity of total PSA and also to reduce the need for 20% of unnecessary biopsies. Tertiary hospital laboratories ought to be appropriately equipped to offer these tests for improved patient outcomes. Objective: The objective was to determine the proportion of Nigerian tertiary care laboratories that offer quantitative total and free PSA testing. Materials and Methods: A cross-sectional survey was carried out in functional government-owned tertiary hospitals in all the geopolitical zones of Nigeria. Respondents were drawn from the Laboratory section of each hospital. Data were collected using semi-structured self-administered questionnaires and analyzed using SPSS version 22. Results: The study included a total of 34 tertiary care laboratories. The mean (SD) age of respondents was 43.71 (5.2) years. Of the surveyed hospitals, 27 (79.41%) had facilities for PSA testing, whereas 7 (20.59%) had no functional PSA testing facility. Of those with a functional testing facility, 27 (100%) had facilities for total PSA whereas 12 (44.44%) had facilities for free PSA. Three facilities [3 (42.85%)] out of the seven facilities with no functional testing facilities cited equipment breakdown as the reason. Conclusion: Availability of PSA testing facilities was not adequate in tertiary care laboratories in Nigeria, with free PSA facilities being less than total PSA facilities. More support is needed in making these important testing facilities more readily available in Nigerian tertiary healthcare laboratories.
背景:前列腺特异性抗原(PSA)检测已被世界卫生组织推荐用于前列腺癌筛查。总PSA和游离PSA与直肠指检的联合使用据说可以提高总PSA的敏感性和特异性,并减少20%不必要的活检。三级医院的实验室应该配备适当的设备,以提供这些检测,以改善患者的预后。目的:目的是确定尼日利亚三级保健实验室提供定量总和免费PSA检测的比例。材料和方法:在尼日利亚所有地缘政治地区的功能性政府所有三级医院进行了横断面调查。受访者来自每家医院的化验科。采用半结构化自填问卷收集数据,并使用SPSS 22进行分析。结果:本研究共纳入34家三级医疗实验室。受访者的平均(SD)年龄为43.71(5.2)岁。27家医院(79.41%)具备PSA检测设备,7家医院(20.59%)不具备PSA功能检测设备。在拥有功能检测设施的机构中,27家(100%)拥有进行总PSA检测的设施,而12家(44.44%)拥有免费PSA检测的设施。在7个没有功能测试设施的设施中,有3个设施[3个(42.85%)]将设备故障作为原因。结论:尼日利亚三级保健实验室PSA检测设施的可用性不足,免费PSA设施少于总PSA设施。需要更多的支持,使尼日利亚三级保健实验室更容易获得这些重要的检测设施。
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引用次数: 1
A comparative study of skin to epidural distance at lumbar region using median and paramedian techniques 腰段皮肤到硬膜外距离的中位和旁位技术对比研究
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_23_22
Josepha Achi, A. Amucheazi, Virginus Ajuzieogu, T. Onyeka
Background: The median and the paramedian approaches are used to access the epidural space. Median approach is commonly used but can be technically difficult in certain patients. The paramedian approach is the alternative. Success rate during the blind procedure is determined by the skin to epidural distance (SED). SED in turn is affected by patients’ anthropometric characteristics. Prediction of the SED serves to determine the depth of needle advancement in order to improve the success rate. Objectives: The study compared the SED using median vs. paramedian approaches, the time required to access the epidural space, place the catheter, and investigate anthropometric factors which may have influenced this distance among the participants. Materials and Methods: The study was a blinded randomized controlled study. Following ethical approval and informed consent, 60 women scheduled for elective gynecological procedures were allocated to one of the two groups: Group M (median) (30) and Group PM (paramedian) (30). Results: The SED was longer using the PM approach. The mean time it took to gain access was shorter in the PM group. The mean SED increased as the body mass index increased in both groups (P < 0.0001). There was a significant association of anthropometric measurements with the SED using both approaches. Conclusion: The study showed that the SED was longer in the PM group. Also as the patient’s anthropometric measurements increased, so did the SED.
背景:中位入路和旁位入路用于进入硬膜外腔。中位入路是常用的,但在某些患者中可能存在技术上的困难。辅助人员方法是另一种选择。盲手术的成功率取决于皮肤到硬膜外的距离(SED)。SED反过来又受到患者人体测量特征的影响。SED的预测有助于确定针的推进深度,以提高成功率。目的:本研究比较了采用中位入路与旁位入路的SED,进入硬膜外空间、放置导管所需的时间,并调查了可能影响参与者距离的人体测量因素。材料与方法:本研究为盲法随机对照研究。在伦理批准和知情同意后,60名计划进行选择性妇科手术的妇女被分配到两组中的一组:M组(中位数)(30)和PM组(辅助人员)(30)。结果:使用PM方法,SED更长。PM组获得访问权限所需的平均时间更短。两组患者的平均SED随体重指数的增加而增加(P < 0.0001)。使用这两种方法,人体测量值与SED有显著的关联。结论:研究表明PM组的SED时间更长。此外,随着患者人体测量值的增加,SED也随之增加。
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引用次数: 0
Willingness to Pay (WTP) for Community-based Health Insurance Scheme (CBHIS) in a Nigerian State 尼日利亚某州社区健康保险计划的支付意愿(WTP)
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_42_21
C. Idoko, Chuka Obienu
Background: Since the turn of the millennium, efforts across the world have been aimed at promoting good living and reducing poverty. This has resulted in countries taking necessary steps to ensure increased access to affordable health care by promoting Universal Health Coverage. Nigeria is not an exemption especially as private health spending has its own substantial impoverishing effects on households. Objective: The objective of this study was to study willingness to pay (WTP) for Community-based Health Insurance Scheme in a Nigerian State. Materials and Methods: The study sample was purposively selected to cover the three senatorial zones of Enugu State, Nigeria. A questionnaire was used to collect data from the respondents that were randomly selected. Focus group discussions were held to collect qualitative data. Key variables which included WTP for in- and outpatient care for the different stated amount of of money in naira and dollar: ₦400 ($1.0), ₦500 ($1.25), ₦1000 ($2.5) or more) were compared across socio-economic status (SES) groups using “asset holding and level of WTP” with the groups classified into SES quartiles. Results: Most respondents were neither WTP a minimum of ₦400 ($1.0) nor a maximum of ₦1000 ($2.5) for inpatient or outpatient care. The overall maximum amount to pay by the groups was ₦500 ($1.25), whereas the minimum amount across the communities was ₦50 ($0.125). Conclusion: There was a ceiling of maximum/minimum willing amounts to pay across the different socio-economic strata and these ceilings were observed to be low.
背景:自世纪之交以来,全世界都在努力促进美好生活和减少贫困。这促使各国采取必要步骤,通过促进全民健康覆盖,确保更多的人获得负担得起的卫生保健。尼日利亚也不能幸免,特别是因为私人保健支出本身对家庭造成了严重的贫困影响。目的:本研究的目的是研究尼日利亚州社区医疗保险计划的支付意愿(WTP)。材料与方法:有目的地选择尼日利亚埃努古州的三个参议院区作为研究样本。采用问卷调查的方式从随机选择的受访者中收集数据。举行焦点小组讨论以收集定性数据。使用“资产持有和WTP水平”将各社会经济地位(SES)群体的主要变量(包括以奈拉和美元表示的不同金额的住院和门诊护理WTP:奈拉400(1.0美元)、奈拉500(1.25美元)、奈拉1000(2.5美元)或更多)与按社会经济地位四分位数划分的群体进行比较。结果:大多数应答者既没有最低奈拉400(1.0美元)的贷款,也没有最高奈拉1000(2.5美元)的住院或门诊贷款。各团体支付的总最高款额为500奈拉(1.25美元),而各社区的最低款额为50奈拉(0.125美元)。结论:在不同的社会经济阶层中,有一个最高/最低愿意支付金额的上限,而这些上限被观察到很低。
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引用次数: 0
Pancreatic Calcification among Children with Childhood Diabetes in Abakaliki, Nigeria: Could This Be Fibrocalculous Pancreatic Diabetes? 尼日利亚Abakaliki儿童糖尿病患者胰腺钙化:这可能是纤维结石性胰腺糖尿病吗?
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_36_21
M. Ibekwe, C. Ogugua, U. Chikani, R. Ibekwe, E. Onwe, M. Orji
Introduction: Tropical calcific pancreatitis is known to be associated with malnutrition and insulin-requiring diabetes mellitus. Recent studies suggest that genetic and environmental factors play a role in its etiopathogenesis. Objective: The objectives of this was were to study the prevalence, profile, and outcome of children managed for type 1 diabetes mellitus with pancreatic calcification. Materials and Methods: This was a cross-sectional study of children managed for type 1 diabetes mellitus in the pediatric endocrine unit of Federal Teaching Hospital Abakaliki, Nigeria. All patients who consented underwent ultrasonography of the pancreas. We undertook a case note review to identify factors that may be associated with pancreatic calcification. Results: Thirty-seven children were diagnosed with diabetes mellitus. The mean age was 12.3 years (5–17 years), 21 males and 16 females. Twenty of 37 (54.1%) patients were screened for pancreatic calcifications using abdominal ultrasound. Seventeen of 37 were not studied as nine of them (24.3%) died, six lost to follow-up, and two declined to participate. The mean duration of diabetes mellitus was 2.7 years (3 months–8 years). All patients were managed with a premixed twice-daily insulin regimen. Pancreatic calcification was seen in seven out of the 20 (35%) and was commoner among males and older children. The average glycosylated hemoglobin (Hba1c) was 13 and 11, and average height/weight standard deviation score was –1.9/–1.9 and –1.03/–1.02 in those with calcification and those without, respectively. Conclusion: Tropical calcific pancreatitis is common among children diagnosed with diabetes mellitus in Abakaliki, Nigeria and is associated with morbidity. Routine pancreatic ultrasound of patients with type 1 diabetes mellitus may be necessary.
热带钙化性胰腺炎已知与营养不良和需要胰岛素的糖尿病有关。近年来的研究表明,遗传和环境因素在其发病机制中起作用。目的:本研究的目的是研究儿童1型糖尿病合并胰腺钙化的患病率、概况和结局。材料和方法:这是一项针对尼日利亚Abakaliki联邦教学医院儿科内分泌科治疗1型糖尿病儿童的横断面研究。所有同意的患者都接受了胰腺超声检查。我们进行了一项病例回顾,以确定可能与胰腺钙化相关的因素。结果:37例患儿被诊断为糖尿病。平均年龄12.3岁(5 ~ 17岁),男21例,女16例。37例患者中有20例(54.1%)采用腹部超声检查胰腺钙化。37人中有17人未被研究,其中9人(24.3%)死亡,6人失去随访,2人拒绝参与。糖尿病的平均病程为2.7年(3个月~ 8年)。所有患者均采用每日两次的胰岛素预混方案。20例患者中有7例(35%)出现胰腺钙化,在男性和年龄较大的儿童中更为常见。钙化组和非钙化组的平均糖化血红蛋白(Hba1c)分别为13和11,平均身高/体重标准差分别为-1.9 / -1.9和-1.03 / -1.02。结论:热带钙化性胰腺炎在尼日利亚Abakaliki诊断为糖尿病的儿童中很常见,并与发病率相关。1型糖尿病患者的常规胰腺超声检查可能是必要的。
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引用次数: 0
Predictors of Dietary Diversity among HIV Clients in a Low-resource Tertiary Health Facility in Southeast Nigeria: A Cross-sectional Analytical Study 尼日利亚东南部资源匮乏的三级医疗机构中艾滋病患者饮食多样性的预测因素:一项横断面分析研究
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_39_21
Ifeyinwa L Ezenwosu, N. Ugwunna, M. Ajuba, Osita Ezenwosu, Emmanuel Otache, Ijeoma Ejike
Background: In a resource-limited setting where nutrient availability is a challenge, it may be necessary to determine factors that affect dietary diversity in people living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) as addressing them could lead to better access to diversified diets in this group. Objective: The objective of this study was to determine the factors that influence dietary diversity among HIV clients attending the HIV clinic in a low-resource tertiary health facility. Materials and Methods: An institutional-based cross-sectional study was conducted among HIV clients receiving anti-retroviral therapy in Enugu state, Nigeria. A systematic random sampling technique was employed in selecting the study participants. Bivariate analysis was done using the chi-square test which was further subjected to multivariate logistic regression analyses to determine predictors of dietary diversity. Results: In this study, respondents who earned a family monthly income of 72.5 US dollars and below were 2.6 times less likely to have high dietary diversity (AOR = 0.378, CI = 0.180–0.792) compared to those who earned above 145 dollars. Also, HIV clients on cotrimoxazole prophylaxis were 2.3 times more likely to have high dietary diversity (AOR = 2.304, CI = 1.155–4.598) compared to those who were not on the prophylaxis. Conclusions: High family monthly income and being on cotrimoxazole prophylaxis were predictors of high dietary diversity in People living with HIV/AIDS. Therefore, there is a need to improve the income of PLWHA as well as ensure the ready availability of cotrimoxazole to reduce the rate of opportunistic infections thus leading to better consumption of diversified diets.
背景:在资源有限的环境中,营养物质的供应是一个挑战,可能有必要确定影响人类免疫缺陷病毒/获得性免疫缺陷综合症(HIV/艾滋病)患者饮食多样性的因素,因为解决这些因素可能会导致这一群体更好地获得多样化的饮食。目的:本研究的目的是确定影响在低资源三级卫生机构艾滋病门诊就诊的艾滋病患者饮食多样性的因素。材料和方法:在尼日利亚埃努古州接受抗逆转录病毒治疗的艾滋病毒患者中进行了一项基于机构的横断面研究。采用系统随机抽样技术选择研究对象。采用卡方检验进行双变量分析,并进一步进行多变量logistic回归分析,以确定饮食多样性的预测因素。结果:在本研究中,家庭月收入为72.5美元及以下的受访者与家庭月收入为145美元以上的受访者相比,饮食多样性高的可能性低2.6倍(AOR = 0.378, CI = 0.180-0.792)。此外,接受复方新诺明预防的HIV患者饮食多样性高的可能性是未接受预防的患者的2.3倍(AOR = 2.304, CI = 1.155-4.598)。结论:家庭月收入高和复方新诺明预防是HIV/AIDS患者饮食多样性高的预测因素。因此,有必要提高艾滋病感染者的收入,并确保复方新诺明的可得性,以减少机会性感染率,从而使人们更好地消费多样化的饮食。
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引用次数: 0
Prevalence of Controlled Blood Pressure among Hypertensive Patients and Determinants of Hypertensive Complications in a Nigerian Population 尼日利亚人群中高血压患者控制血压的患病率和高血压并发症的决定因素
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_3_22
C. Kassy, C. Okeke, A. Ndu, A. Umeobieri
Background: The impact of uncontrolled hypertension results in undesirable cardiovascular events. Hence, there is a need to emphasize on adequate control of blood pressure. Objectives: The objectives of this study were to determine the prevalence and determinants of controlled blood pressure and the complications of hypertension in a tertiary hospital in Nigeria. Materials and Methods: This was a retrospective study of 257 patients of Cardiology Unit of University of Nigeria Teaching Hospital diagnosed with hypertension from 2014 to 2018. A proforma-designed questionnaire was used to retrieve responses from the patients’ medical records. Data were entered and analyzed using Statistical Package for Social Sciences version 20. The level of significance was set at 0.05. Results: The prevalence of controlled blood pressure was 35.8% with mean blood pressure of 112.39/72.72 mmHg. Adherence to drug therapy was found to be associated with controlled blood pressure (χ2 = 8.370, P = 0.005). Two-thirds of patients diagnosed with hypertension developed complications of which hypertensive heart disease, stroke, and chronic kidney diseases were the commonest. Age (χ2 = 9.629, P = 0.008) and the initial presenting diagnosis (χ2 = 7.662, P = 0.004) were factors associated with the development of complications. Conclusion: Adequate blood pressure control is still a challenge among hypertensive patients in the study population. A comprehensive program is advocated for the control of blood pressure that will accommodate drug adherence in addition to education, and socio-behavioral change modifications.
背景:不受控制的高血压会导致不良的心血管事件。因此,有必要强调适当控制血压。目的:本研究的目的是确定尼日利亚一家三级医院控制血压和高血压并发症的患病率和决定因素。材料与方法:回顾性研究2014 - 2018年尼日利亚大学教学医院心内科诊断为高血压的257例患者。采用形式设计的问卷从患者的医疗记录中检索答案。数据输入和分析使用统计软件包的社会科学版本20。显著性水平设为0.05。结果:血压控制率为35.8%,平均血压为112.39/72.72 mmHg。药物治疗依从性与血压控制相关(χ2 = 8.370, P = 0.005)。三分之二被诊断为高血压的患者出现并发症,其中高血压心脏病、中风和慢性肾病是最常见的。年龄(χ2 = 9.629, P = 0.008)和初诊(χ2 = 7.662, P = 0.004)是并发症发生的相关因素。结论:适当的血压控制仍然是研究人群中高血压患者面临的挑战。一项全面的血压控制方案,除了教育和社会行为改变之外,还将适应药物依从性。
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引用次数: 0
Health risk behavior of adolescents with sickle cell disease in Nigeria 尼日利亚镰状细胞病青少年的健康风险行为
Pub Date : 2022-07-01 DOI: 10.4103/ijmh.ijmh_9_22
P. Ajike, K. Adediran, T. Kotila, M. Dairo
Background: The advances in medical practice have increased the average life expectancy of people living with sickle cell disease (SCD) to 54 years. The high prevalence rates of SCD in Nigeria therefore highlights the need for research that will support overall disease management. Objective: To determine the health risk behavior (HRB) of adolescents with sickle cell disease in Nigeria. Materials and methods: In a cross-sectional descriptive survey using purposive sampling method, 122 adolescents with SCD attending sickle cell clubs in Ogun State, Nigeria were selected for the study. A 58-item questionnaire adapted from the Youth Risk Behavior Survey (YRBS) instrument developed by Centre for Disease Control and Prevention (CDC) was used to collect data from the adolescents. Results: The mean age of the respondents was 15.7 ± 2.3 years, there were more females (58.2%) than males (41.2%). Majority were from a monogamous family setting and average to large family size (≥3siblings) (63% and 76% respectively) and only 6% of the parents had no formal education. The mean ages at first sexual intercourse, cigarette smoking and alcohol use were 16 ± 5.7, 15.7 ± 0.7, and 14.9 ± 1.9 years respectively. One-fifth (21.3%) have had sex and half (50%) of them have had sex by the age of 17. Over one-tenth (13.9%) had smoked cigarette while 14.8% had taken alcohol. Adolescents from monogamous family background were more likely to be involved in substance abuse (χ2: 4.99; P=0.008) and exposed to sexual activities (χ2: 10.9; P=0.004) than those from polygamous or single parent family. Conclusion: It was concluded that adolescents with SCD are involved in HRB and may be dependent on family characteristics. It is recommended that regular health care of chronically ill adolescents should include screening and counselling for HRBs.
背景:医学实践的进步使镰状细胞病(SCD)患者的平均预期寿命增加到54岁。因此,尼日利亚SCD的高流行率突出表明需要进行研究,以支持全面的疾病管理。目的:了解尼日利亚青少年镰状细胞病的健康危险行为(HRB)。材料和方法:采用有目的抽样方法进行横断面描述性调查,选取尼日利亚奥贡州参加镰状细胞俱乐部的122名SCD青少年进行研究。采用美国疾病控制与预防中心(CDC)开发的青少年危险行为调查(YRBS)工具的58项调查问卷收集青少年数据。结果:受访患者平均年龄为15.7±2.3岁,女性(58.2%)多于男性(41.2%)。大多数来自一夫一妻制家庭环境和平均到大家庭(≥3个兄弟姐妹)(分别为63%和76%),只有6%的父母没有接受过正规教育。初次性行为、吸烟和饮酒的平均年龄分别为16±5.7岁、15.7±0.7岁和14.9±1.9岁。五分之一(21.3%)的人有过性行为,其中一半(50%)的人在17岁之前有过性行为。超过十分之一(13.9%)的人吸烟,14.8%的人饮酒。来自一夫一妻制家庭背景的青少年更容易发生药物滥用(χ2: 4.99;P=0.008)和暴露于性活动(χ2: 10.9;P=0.004),高于单亲家庭和一夫多妻家庭。结论:青少年SCD与HRB有关,可能与家庭特征有关。建议对患有慢性疾病的青少年的定期保健应包括对乙肝的筛查和咨询。
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引用次数: 0
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International Journal of Medicine and Health Development
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