Pub Date : 2011-01-01DOI: 10.1504/IJFSNPH.2011.044559
Ajab Khan, S. Malik, Abid A Khan, Ashfaq Ahmad, Roshan Ali
The present study aimed to evaluate the effects of tobacco on different biochemical and physical parameters in type 2 diabetic subjects from Dera Ismail Khan, NWFP, Pakistan. A total of 100 chronic type 2 diabetic patients of different age and sex with no tobacco addiction and with tobacco addiction were requested to volunteer their complete biodata on a given Performa. Blood biochemical parameters were determined using Automatic Chemistry Analyzer. Mean fasting glucose level of smoking, snuff, and both addicted diabetic group was non-significantly higher with p -value > 0.05 as compared to control group. Similarly glycosylated hemoglobin level of smoking, snuff addicted diabetic group was also non-significantly higher but that of both addicted group was non-significantly lower with p -value > 0.05. Similarly the cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol levels of smoking, snuff and both addicted diabetic groups were non-significantly changed as compared to diabetic control group with p -value > 0.05 respectively. It is concluded that there is no additional adverse effect of tobacco on the biochemistry of diabetic patients.
{"title":"Effects of tobacco (smoking and snuffing) in type 2 diabetic patients","authors":"Ajab Khan, S. Malik, Abid A Khan, Ashfaq Ahmad, Roshan Ali","doi":"10.1504/IJFSNPH.2011.044559","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2011.044559","url":null,"abstract":"The present study aimed to evaluate the effects of tobacco on different biochemical and physical parameters in type 2 diabetic subjects from Dera Ismail Khan, NWFP, Pakistan. A total of 100 chronic type 2 diabetic patients of different age and sex with no tobacco addiction and with tobacco addiction were requested to volunteer their complete biodata on a given Performa. Blood biochemical parameters were determined using Automatic Chemistry Analyzer. Mean fasting glucose level of smoking, snuff, and both addicted diabetic group was non-significantly higher with p -value > 0.05 as compared to control group. Similarly glycosylated hemoglobin level of smoking, snuff addicted diabetic group was also non-significantly higher but that of both addicted group was non-significantly lower with p -value > 0.05. Similarly the cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol levels of smoking, snuff and both addicted diabetic groups were non-significantly changed as compared to diabetic control group with p -value > 0.05 respectively. It is concluded that there is no additional adverse effect of tobacco on the biochemistry of diabetic patients.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"38 1","pages":"196"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75793222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-01-01DOI: 10.1504/IJFSNPH.2011.044624
D. L. Harris, A. Mahapatra, B. L. Jones, G. Kannan
Experiments were conducted using low-voltage alternating current (AC) to inactivate surface adherent Escherichia coli O157:H7 on beef samples. Beef samples (25 × 25 × 25 mm) were inoculated with E. coli and placed in sodium chloride solution which served as an electrolyte. Electrical current (AC) was applied to the beef samples. Frequencies of 1, 10, and 100 kHz and current intensities of 300 mA (15 mA/cm 2 ), 600 mA (30 mA/cm 2 ), and 900 mA (45 mA/cm 2 ) at treatment durations of 2, 8, and 16 min were investigated. A 2.15 log 10 reduction was achieved using a 16 min treatment time with 900 mA (45 mA/cm 2 ) current intensity and 1 kHz frequency.
采用低压交流电(AC)灭活牛肉样品表面粘附的大肠杆菌O157:H7。用大肠杆菌接种牛肉样品(25 × 25 × 25 mm)，置于氯化钠溶液中作为电解质。对牛肉样品施加电流(AC)。研究了1、10和100 kHz的频率和300 mA (15 mA/cm 2)、600 mA (30 mA/cm 2)和900 mA (45 mA/cm 2)的电流强度，处理时间分别为2,8和16 min。在900 mA (45 mA/ cm2)电流强度和1 kHz频率下，使用16分钟的处理时间，实现了2.15 log 10的降低。
{"title":"Efficacy of low-voltage AC for inactivating surface adherent Escherichia coli O157:H7 on beef","authors":"D. L. Harris, A. Mahapatra, B. L. Jones, G. Kannan","doi":"10.1504/IJFSNPH.2011.044624","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2011.044624","url":null,"abstract":"Experiments were conducted using low-voltage alternating current (AC) to inactivate surface adherent Escherichia coli O157:H7 on beef samples. Beef samples (25 × 25 × 25 mm) were inoculated with E. coli and placed in sodium chloride solution which served as an electrolyte. Electrical current (AC) was applied to the beef samples. Frequencies of 1, 10, and 100 kHz and current intensities of 300 mA (15 mA/cm 2 ), 600 mA (30 mA/cm 2 ), and 900 mA (45 mA/cm 2 ) at treatment durations of 2, 8, and 16 min were investigated. A 2.15 log 10 reduction was achieved using a 16 min treatment time with 900 mA (45 mA/cm 2 ) current intensity and 1 kHz frequency.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"25 1","pages":"214"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88738784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-05DOI: 10.1504/IJFSNPH.2010.032031
R. A. Hai, H. Raghi, Madiha Said Abd El Razik, N. Kamal
Obesity is associated with higher prevalence of type2 diabetes and hypertension. Objectives were determining prevalence of obesity, type2 diabetes and hypertension in a rural village. This cross sectional study included 1,000 male and female ≥ 20 years. Blood pressure, anthropometry, fasting and 2 hr post-prandial glucose were determined. Results showed 29.7% overweight and 45.6% obese. Visceral obesity, by waist circumference (WC), was 24.4% in males and 69.2% in females. Prevalence of pre-diabetes and diabetes was 5.7% and 9.6%, respectively, while hypertension was 32.1%. BMIcut-off diabetes predictors were 27.5-29.8 Kg/m² while hypertension predictors were 26.05–28.6 Kg/m². WCcut-off diabetes predictors were 93.5 cm in males and 97.5 cm for females, while for hypertension were 90.5 and 94.5 cm similarly. Logistic regression showed WC, age and family history of diabetes increasing risk of comorbidities. To conclude, obesity is associated with increased prevalence of type2 diabetes and hypertension thus we recommend introducing simple anthropometry for early detection of obesity and its' comorbidities.
{"title":"The role of anthropometric indices in predicting comorbidities of obesity in a rural Egyptian population","authors":"R. A. Hai, H. Raghi, Madiha Said Abd El Razik, N. Kamal","doi":"10.1504/IJFSNPH.2010.032031","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2010.032031","url":null,"abstract":"Obesity is associated with higher prevalence of type2 diabetes and hypertension. Objectives were determining prevalence of obesity, type2 diabetes and hypertension in a rural village. This cross sectional study included 1,000 male and female ≥ 20 years. Blood pressure, anthropometry, fasting and 2 hr post-prandial glucose were determined. Results showed 29.7% overweight and 45.6% obese. Visceral obesity, by waist circumference (WC), was 24.4% in males and 69.2% in females. Prevalence of pre-diabetes and diabetes was 5.7% and 9.6%, respectively, while hypertension was 32.1%. BMIcut-off diabetes predictors were 27.5-29.8 Kg/m² while hypertension predictors were 26.05–28.6 Kg/m². WCcut-off diabetes predictors were 93.5 cm in males and 97.5 cm for females, while for hypertension were 90.5 and 94.5 cm similarly. Logistic regression showed WC, age and family history of diabetes increasing risk of comorbidities. To conclude, obesity is associated with increased prevalence of type2 diabetes and hypertension thus we recommend introducing simple anthropometry for early detection of obesity and its' comorbidities.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"50 1","pages":"16-26"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86736709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-05DOI: 10.1504/IJFSNPH.2010.032033
R. Lokhande, P. Singare, Mahadeo L. Andhale, R. Acharya, A. Nair, A. Reddy
Specific parts (fruits and seeds) of different medicinal plants often used in Indian Ayurvedic system were analysed for 18 elements (K, Mn, Na, Fe, Zn, Cu, Co, Br, Sm, Cl, La, Al, Cr, Ca Cd, Ni, Pb and Hg) by employing instrumental neutron activation analysis (INAA) and atomic absorption spectroscopy (AAS) techniques. The samples were irradiated with thermal neutrons in a nuclear reactor and the induced activities were counted by γ-ray spectrometry using efficiency calibrated high-resolution high purity germanium (HPGe) detector. Most of the medicinal plants were found to be rich in one or more of the elements under study. The elemental concentration in different part of medicinal plants and their biological effects on human being are discussed. It is expected that the experimental data on the elemental concentrations will be helpful in the synthesis of new Ayurvedic drugs for the control and cure of various diseases.
{"title":"Determination of macro, micro nutrient and trace element concentrations in Indian medicinal plants using instrumental neutron activation analysis and atomic absorption spectroscopy techniques","authors":"R. Lokhande, P. Singare, Mahadeo L. Andhale, R. Acharya, A. Nair, A. Reddy","doi":"10.1504/IJFSNPH.2010.032033","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2010.032033","url":null,"abstract":"Specific parts (fruits and seeds) of different medicinal plants often used in Indian Ayurvedic system were analysed for 18 elements (K, Mn, Na, Fe, Zn, Cu, Co, Br, Sm, Cl, La, Al, Cr, Ca Cd, Ni, Pb and Hg) by employing instrumental neutron activation analysis (INAA) and atomic absorption spectroscopy (AAS) techniques. The samples were irradiated with thermal neutrons in a nuclear reactor and the induced activities were counted by γ-ray spectrometry using efficiency calibrated high-resolution high purity germanium (HPGe) detector. Most of the medicinal plants were found to be rich in one or more of the elements under study. The elemental concentration in different part of medicinal plants and their biological effects on human being are discussed. It is expected that the experimental data on the elemental concentrations will be helpful in the synthesis of new Ayurvedic drugs for the control and cure of various diseases.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"01 1","pages":"33-44"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80136526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-05DOI: 10.1504/IJFSNPH.2010.032034
C. Macharia-Mutie, I. Brouwer, A. Mwangi, F. Kok
A cross-sectional study was carried out among 280 children (12-23 months), Mwingi district, Kenya. Complementary foods were introduced at age 2.5 ± 1.7 months and the mean duration of breastfeeding was 10.5 ± 4.1 months. An unfortified maize porridge was the main complementary food. At least 60% of the children in all the dietary diversity terciles consumed starchy staples and oils in the preceding 24 hr. The mean dietary diversity score was 4.9 ± 1.3 and 4.3 ± 1.0 out of a possible score of 14 and 8 as suggested by FAO, respectively. Dietary diversity was limited in animal products. Deficits in dietary energy, iron and zinc were found due to early introduction of complementary foods and low consumption of food rich in iron. Establishing local solutions to increase dietary diversity and promote use of foods rich in iron and proteins to improve available complementary diets are needed.
{"title":"Complementary feeding practices and dietary intake among children 12-23 months in Mwingi district, Kenya","authors":"C. Macharia-Mutie, I. Brouwer, A. Mwangi, F. Kok","doi":"10.1504/IJFSNPH.2010.032034","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2010.032034","url":null,"abstract":"A cross-sectional study was carried out among 280 children (12-23 months), Mwingi district, Kenya. Complementary foods were introduced at age 2.5 ± 1.7 months and the mean duration of breastfeeding was 10.5 ± 4.1 months. An unfortified maize porridge was the main complementary food. At least 60% of the children in all the dietary diversity terciles consumed starchy staples and oils in the preceding 24 hr. The mean dietary diversity score was 4.9 ± 1.3 and 4.3 ± 1.0 out of a possible score of 14 and 8 as suggested by FAO, respectively. Dietary diversity was limited in animal products. Deficits in dietary energy, iron and zinc were found due to early introduction of complementary foods and low consumption of food rich in iron. Establishing local solutions to increase dietary diversity and promote use of foods rich in iron and proteins to improve available complementary diets are needed.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"94 2 1","pages":"45-56"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87667260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-05DOI: 10.1504/IJFSNPH.2010.032036
N. Nnam, U. Udofia
The study determined the effect of daily consumption of periwinkle on the iron status of pregnant women. One hundred and twenty pregnant women in their second trimester who were anaemic were selected from the antenatal clinic of the Bishop Shanahan Hospital, Nsukka, Nigeria. The women were randomly assigned to two groups – test group (TG) n = 60 and control group (CG) n = 60. Women in the TG consumed 50 g of periwinkle daily for six weeks with their normal diet while those in the CG consumed only the normal diet. Haemoglobin (Hb) and serum ferritin (SF) levels of the women were taken at baseline and at the end of the study. The mean Hb and SF concentrations of the pregnant women increased from 10.87 to 12.24 g dl−1 and 11.21 to 19.67 μg l−1, respectively in the TG at the end of the study. There were no significant changes in the mean Hb (10.41 vs. 10.46 g dl−1) and SF (11.34 vs. 11.36 μg l−1) concentrations of the women in the CG.
该研究确定了每天食用长春花对孕妇铁含量的影响。从尼日利亚恩苏卡主教沙纳汉医院产前诊所挑选了120名妊娠中期贫血的孕妇。女性随机分为两组，实验组(TG) n = 60，对照组(CG) n = 60。在六周的时间里，TG组的女性在正常饮食的情况下每天食用50克长春花，而CG组的女性只食用正常饮食。在基线和研究结束时，测量妇女的血红蛋白(Hb)和血清铁蛋白(SF)水平。研究结束时，孕妇TG中Hb和SF的平均浓度分别从10.87增加到12.24 g dl - 1和11.21增加到19.67 g dl - 1。在CG中，女性的平均Hb (10.41 vs. 10.46 g dl−1)和SF (11.34 vs. 11.36 g dl−1)浓度没有显著变化。
{"title":"Food-based strategy to improve iron status of pregnant women in Nigeria.","authors":"N. Nnam, U. Udofia","doi":"10.1504/IJFSNPH.2010.032036","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2010.032036","url":null,"abstract":"The study determined the effect of daily consumption of periwinkle on the iron status of pregnant women. One hundred and twenty pregnant women in their second trimester who were anaemic were selected from the antenatal clinic of the Bishop Shanahan Hospital, Nsukka, Nigeria. The women were randomly assigned to two groups – test group (TG) n = 60 and control group (CG) n = 60. Women in the TG consumed 50 g of periwinkle daily for six weeks with their normal diet while those in the CG consumed only the normal diet. Haemoglobin (Hb) and serum ferritin (SF) levels of the women were taken at baseline and at the end of the study. The mean Hb and SF concentrations of the pregnant women increased from 10.87 to 12.24 g dl−1 and 11.21 to 19.67 μg l−1, respectively in the TG at the end of the study. There were no significant changes in the mean Hb (10.41 vs. 10.46 g dl−1) and SF (11.34 vs. 11.36 μg l−1) concentrations of the women in the CG.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"81 1","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88966553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-05DOI: 10.1504/IJFSNPH.2010.032032
S. Gillani, Azhar S. Sulaiman, Forouzan Bayat Nejad
Patient care is a concerning issue representing the nosocomial infection transmission especially hospital-acquired pneumonia (HAP). This study aims to identify the percentage statistics of HAP among the hospitalised patients of general ward. Also, among the objectives is to investigate the etiological pattern with the prescribed antibiotics in the concomitant treatment. A two-year retrospective cohort analysis was made from January 2007 to December 2008 in General Hospital Pulau Pinang, Malaysia. Results identified the increase rate of HAP and secondary increase rate of mortality with diagnosed pathogen. More profound analysis showed the inappropriate use of antibiotics that can be the possible cause of HAP and lead to future increase in resistance pattern in pathogens. Conclusion has been made on the recommendation of the clinical evidence-based treatment as to reduce the risk of other morbidities in a clause to reduce the spread of nosocomial infections.
{"title":"Inpatient care and microbial surveillance during year 2007-2008; retrospective evaluation of hospital-acquired pneumonia (HAP) in General Hospital Pulau Pinang, Malaysia","authors":"S. Gillani, Azhar S. Sulaiman, Forouzan Bayat Nejad","doi":"10.1504/IJFSNPH.2010.032032","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2010.032032","url":null,"abstract":"Patient care is a concerning issue representing the nosocomial infection transmission especially hospital-acquired pneumonia (HAP). This study aims to identify the percentage statistics of HAP among the hospitalised patients of general ward. Also, among the objectives is to investigate the etiological pattern with the prescribed antibiotics in the concomitant treatment. A two-year retrospective cohort analysis was made from January 2007 to December 2008 in General Hospital Pulau Pinang, Malaysia. Results identified the increase rate of HAP and secondary increase rate of mortality with diagnosed pathogen. More profound analysis showed the inappropriate use of antibiotics that can be the possible cause of HAP and lead to future increase in resistance pattern in pathogens. Conclusion has been made on the recommendation of the clinical evidence-based treatment as to reduce the risk of other morbidities in a clause to reduce the spread of nosocomial infections.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"13 1","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82547153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-05DOI: 10.1504/IJFSNPH.2010.032035
A. ElBaky, Tarek Mohamad Farid El Shaer, A. Elwan, Hanaa Rasmy
Passive cigarette smoking and obesity during pregnancy are risk factors for adverse outcome in infant. Elevated umbilical cord neonatal nucleated red blood cells (NRBCs) have been suggested as a marker of intrauterine foetal hypoxia. Aim to demonstrate whether maternal risk factors during pregnancy are capable of elevating circulating NRBCs measured at birth. We compared the count of NRBCs in the cord blood in three groups. Group I neonates born to obese mothers, group I) neonates born to mothers exposed to tobacco smoke during pregnancy and control group III. The results reveal that maternal body mass index and infant birth weight were significantly higher in group I (p = < 0.001 and 0.037, respectively). The absolute NRBC count was higher in groups I and II compared to control group (p = 0.02 and 0.01, respectively). In conclusion, the neonates of obese mothers and passive maternal smoking have increased NRBCs at birth.
{"title":"Effect of maternal obesity and passive smoking on neonatal nucleated red blood cells","authors":"A. ElBaky, Tarek Mohamad Farid El Shaer, A. Elwan, Hanaa Rasmy","doi":"10.1504/IJFSNPH.2010.032035","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2010.032035","url":null,"abstract":"Passive cigarette smoking and obesity during pregnancy are risk factors for adverse outcome in infant. Elevated umbilical cord neonatal nucleated red blood cells (NRBCs) have been suggested as a marker of intrauterine foetal hypoxia. Aim to demonstrate whether maternal risk factors during pregnancy are capable of elevating circulating NRBCs measured at birth. We compared the count of NRBCs in the cord blood in three groups. Group I neonates born to obese mothers, group I) neonates born to mothers exposed to tobacco smoke during pregnancy and control group III. The results reveal that maternal body mass index and infant birth weight were significantly higher in group I (p = < 0.001 and 0.037, respectively). The absolute NRBC count was higher in groups I and II compared to control group (p = 0.02 and 0.01, respectively). In conclusion, the neonates of obese mothers and passive maternal smoking have increased NRBCs at birth.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"8 1","pages":"57-63"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82831739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-05DOI: 10.1504/IJFSNPH.2010.032030
N. Amr, Salwa Elbatrawy, S. Atef, Rasha F. Darwish, Adham Hegazy
Leptin plays a role in foetal growth. Osteocalcin, a bone specific protein, reflects bone formation rate. This study aims to investigate the effect of leptin and osteocalcin on physical growth of newborns. About 40 full-term and 41 preterm healthy babies were included. Umbilical cord samples were analysed for leptin and osteocalcin. Anthropometric measurements were taken on newborns. Leptin was significantly higher in full terms compared to preterms with no significant difference in osteocalcin. A significant positive correlation existed between leptin and anthropometric measurements in both groups. Osteocalcin was positively correlated in full terms and negatively correlated in preterms with most measurements. A positive correlation between leptin and osteocalcin was found in full terms only. The study documented the association of leptin and osteocalcin with physical growth of full-term babies. This was true regarding leptin in preterms, but not osteocalcin which could be explained by excess bone turnover in preterms.
{"title":"The relation between leptin and osteocalcin and various anthropometric measures in preterm and full-term babies.","authors":"N. Amr, Salwa Elbatrawy, S. Atef, Rasha F. Darwish, Adham Hegazy","doi":"10.1504/IJFSNPH.2010.032030","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2010.032030","url":null,"abstract":"Leptin plays a role in foetal growth. Osteocalcin, a bone specific protein, reflects bone formation rate. This study aims to investigate the effect of leptin and osteocalcin on physical growth of newborns. About 40 full-term and 41 preterm healthy babies were included. Umbilical cord samples were analysed for leptin and osteocalcin. Anthropometric measurements were taken on newborns. Leptin was significantly higher in full terms compared to preterms with no significant difference in osteocalcin. A significant positive correlation existed between leptin and anthropometric measurements in both groups. Osteocalcin was positively correlated in full terms and negatively correlated in preterms with most measurements. A positive correlation between leptin and osteocalcin was found in full terms only. The study documented the association of leptin and osteocalcin with physical growth of full-term babies. This was true regarding leptin in preterms, but not osteocalcin which could be explained by excess bone turnover in preterms.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"145 1","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"2010-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86218322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-11-19DOI: 10.1504/IJFSNPH.2009.029277
Yusr M. I. Kazem, M. Hussein, Soraya Taher El-Damhogy, A. S. A. Elazeem
Several studies suggested that elevated plasma total homocysteine (tHcy) concentrations are associated with cognitive impairment and dementia. High plasma homocysteine concentrations can be largely attributed to inadequate status of folic acid and vitamin B12. On the other hand, data from several studies indicate that plasma homocysteine increases with age, independent of vitamin status. We investigated the relation between plasma tHcy, vitamin B12 and folic acid levels and cognitive functions in an elderly Egyptian group. We also studied the effect of vitamin B12 and folic acid supplementation on plasma tHcy and cognitive functions. About 56 subjects (30 males and 26 females) similar in socio-economic class (upper-middle), with an age range of 60-70 years completed the study course. All were healthy working professionals. Clinical, nutritional and anthropometric evaluations were performed. Cognitive function evaluation using the Kendrick Battery for detecting dementia was applied. Biochemical analysis for blood homocysteine, vitamin B12 and folic acid was performed. All evaluations were performed at the beginning of the study and after four months of supplementation with biscuits rich in vitamin B12 and folic acid. The results of the study show that there is a significant correlation between plasma tHcy and cognitive functions, both object learning test (OLT) (short-term memory) and digit copying test (DCT) (attention focus) both before p (<0.01) and after p (<0.01) vitamin supplementation and also between vitamin B12 and cognitive functions before and after supplementation p (<0.05). Significant decrease in plasma tHcy and increase in vitamin B12 and folic acid level is recorded after supplementation p (<0.01). There is a significant improvement in cognitive functions, both OLT and DCT after vitamin supplementation p (<0.05). In conclusion, elevated plasma tHcy level and low vitamin B12 levels are positively correlated to impairment in cognitive functions. Vitamin B12 and folic acid supplementation decreased plasma tHcy level and improved cognitive functions. We recommend vitamin B12 and folic acid supplementation for elderly.
{"title":"Homocysteine, vitamin B12 and folic acid plasma levels in relation to cognitive functions in an Egyptian elderly group","authors":"Yusr M. I. Kazem, M. Hussein, Soraya Taher El-Damhogy, A. S. A. Elazeem","doi":"10.1504/IJFSNPH.2009.029277","DOIUrl":"https://doi.org/10.1504/IJFSNPH.2009.029277","url":null,"abstract":"Several studies suggested that elevated plasma total homocysteine (tHcy) concentrations are associated with cognitive impairment and dementia. High plasma homocysteine concentrations can be largely attributed to inadequate status of folic acid and vitamin B12. On the other hand, data from several studies indicate that plasma homocysteine increases with age, independent of vitamin status. We investigated the relation between plasma tHcy, vitamin B12 and folic acid levels and cognitive functions in an elderly Egyptian group. We also studied the effect of vitamin B12 and folic acid supplementation on plasma tHcy and cognitive functions. About 56 subjects (30 males and 26 females) similar in socio-economic class (upper-middle), with an age range of 60-70 years completed the study course. All were healthy working professionals. Clinical, nutritional and anthropometric evaluations were performed. Cognitive function evaluation using the Kendrick Battery for detecting dementia was applied. Biochemical analysis for blood homocysteine, vitamin B12 and folic acid was performed. All evaluations were performed at the beginning of the study and after four months of supplementation with biscuits rich in vitamin B12 and folic acid. The results of the study show that there is a significant correlation between plasma tHcy and cognitive functions, both object learning test (OLT) (short-term memory) and digit copying test (DCT) (attention focus) both before p (<0.01) and after p (<0.01) vitamin supplementation and also between vitamin B12 and cognitive functions before and after supplementation p (<0.05). Significant decrease in plasma tHcy and increase in vitamin B12 and folic acid level is recorded after supplementation p (<0.01). There is a significant improvement in cognitive functions, both OLT and DCT after vitamin supplementation p (<0.05). In conclusion, elevated plasma tHcy level and low vitamin B12 levels are positively correlated to impairment in cognitive functions. Vitamin B12 and folic acid supplementation decreased plasma tHcy level and improved cognitive functions. We recommend vitamin B12 and folic acid supplementation for elderly.","PeriodicalId":14113,"journal":{"name":"International Journal of Food Safety, Nutrition and Public Health","volume":"1 1","pages":"111-124"},"PeriodicalIF":0.0,"publicationDate":"2009-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84398890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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