: This study was aimed at investigating effect of seasonal variation on yield and chemical composition of leaf essential oil of Aframomum Latifolium over a period of twelve months. Fresh leaves of this plant were subjected to hydrodistillation every month for a period of twelve months using an all glass Clevenger apparatus. The volatile oil obtained each month was analyzed by means of gas chromatography/mass spectrometry (GC/MS). The percentage oil yield ranged between 0.03 – 0.15 % v/w for the twelve treatments. Twenty compounds were identified in the volatile leaf oil obtained over a period of twelve months and oxygenated monoterpene was the most dominant constituent. Cajeputol, an oxygenated monoterpene has the highest percentage in the twelve treatments (39.40 – 45.61%). The effect of seasonal variation was established in the yield of the volatile oil in this study as the maximum yield (0.11%) (v/w) was recorded in November. There is a sudden disappearance of limonene in august and September and a rise in the level of cajeputol between august and November. The volatile oils obtained were rich in cajeputol (45.61%) and α-pinene (20.97%) and these compounds had been documented to be a cough suppressant, anti-inflammatory and anti-microbial agents.
{"title":"Effect of Seasonal Variation on the Chemical Composition of Leaf Essential Oil of <i>Aframomum Latifolium </i>(K. Schum) Obtained from Southwest Nigeria","authors":"Ogunmola Oluranti Olagoke, Amusat Mumini Adekunle, Azeez Eniola Morufat, Adedosu Taofik Adewale","doi":"10.11648/j.ijpc.20230901.12","DOIUrl":"https://doi.org/10.11648/j.ijpc.20230901.12","url":null,"abstract":": This study was aimed at investigating effect of seasonal variation on yield and chemical composition of leaf essential oil of Aframomum Latifolium over a period of twelve months. Fresh leaves of this plant were subjected to hydrodistillation every month for a period of twelve months using an all glass Clevenger apparatus. The volatile oil obtained each month was analyzed by means of gas chromatography/mass spectrometry (GC/MS). The percentage oil yield ranged between 0.03 – 0.15 % v/w for the twelve treatments. Twenty compounds were identified in the volatile leaf oil obtained over a period of twelve months and oxygenated monoterpene was the most dominant constituent. Cajeputol, an oxygenated monoterpene has the highest percentage in the twelve treatments (39.40 – 45.61%). The effect of seasonal variation was established in the yield of the volatile oil in this study as the maximum yield (0.11%) (v/w) was recorded in November. There is a sudden disappearance of limonene in august and September and a rise in the level of cajeputol between august and November. The volatile oils obtained were rich in cajeputol (45.61%) and α-pinene (20.97%) and these compounds had been documented to be a cough suppressant, anti-inflammatory and anti-microbial agents.","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85020955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-27DOI: 10.11648/j.ijpc.20230901.11
Abdullah J. Alamami, Samar Ben Zaed, Esra El Naili, Areej Daboub, Naema Elremali, Fatma A. Elshibani, Salim Skaik
{"title":"Determination of Antioxidant Capacity and HPLC Analysis of Gallic Acid Plus Rutin in Some Lamiaceae Plants Growing in the East of Libya","authors":"Abdullah J. Alamami, Samar Ben Zaed, Esra El Naili, Areej Daboub, Naema Elremali, Fatma A. Elshibani, Salim Skaik","doi":"10.11648/j.ijpc.20230901.11","DOIUrl":"https://doi.org/10.11648/j.ijpc.20230901.11","url":null,"abstract":"","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"87 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88422734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-31DOI: 10.11648/j.ijpc.20220806.12
Claude Berenger Ngantchouko Ngalemo, Gisele Laurel Tchiengang Tchoua, Francois Nicaise Bony, Blondin Gatien Tsawo, Patrick Yamen Mbopi, Stephane Kevin Ndengue Langoul, Jean Michel Tekam, Pierre Rene Fotsing Kwetche
{"title":"Polyphenolic and Flavonoids Contents and Antibacterial Activity of Hydro-Ethanolic and Aqueous Extract of Fresh Leaves of Gardenia Aqualla Staph and Hutch (Rubiaceae)","authors":"Claude Berenger Ngantchouko Ngalemo, Gisele Laurel Tchiengang Tchoua, Francois Nicaise Bony, Blondin Gatien Tsawo, Patrick Yamen Mbopi, Stephane Kevin Ndengue Langoul, Jean Michel Tekam, Pierre Rene Fotsing Kwetche","doi":"10.11648/j.ijpc.20220806.12","DOIUrl":"https://doi.org/10.11648/j.ijpc.20220806.12","url":null,"abstract":"","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89736050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-13DOI: 10.11648/j.ijpc.20220806.11
Mohammadreza Gholibeikian, Nastaran Gholami Samali, A. Arvaneh
{"title":"The Cytotoxicity of Analogues Carnosine Dipeptide on Human Glioblastoma Multiforme","authors":"Mohammadreza Gholibeikian, Nastaran Gholami Samali, A. Arvaneh","doi":"10.11648/j.ijpc.20220806.11","DOIUrl":"https://doi.org/10.11648/j.ijpc.20220806.11","url":null,"abstract":"","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78824948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.11648/j.ijpc.20220801.13
Tadesse Bekeshe Rundessa, Birhanu Jelkeba Negeri, Usmael Mohammed Hasan
{"title":"Competency and Attitude of Pharmacists in the Management of Common Ailments Among Community Pharmacy in Adama Town, Adama, Ethiopia, 2021","authors":"Tadesse Bekeshe Rundessa, Birhanu Jelkeba Negeri, Usmael Mohammed Hasan","doi":"10.11648/j.ijpc.20220801.13","DOIUrl":"https://doi.org/10.11648/j.ijpc.20220801.13","url":null,"abstract":"","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89195866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.11648/j.ijpc.20220801.12
Wang Qingliang, Bao Yinping, Bao Sudun, Bao Gaowa, Bao Dugeer, Bao Alatengqimuge, Lian Hanqing, Song Fushun, Zhang Wen, Zhang Tianji, Bao Xilinqiqige, Bao Tegexibaiyin, B. Siqin, Bao Wuhanqimuge
{"title":"The Neuroprotective Effect of the Extract of Traditional Mongolian Medicine Eerdun Wurile in PC12 Cells","authors":"Wang Qingliang, Bao Yinping, Bao Sudun, Bao Gaowa, Bao Dugeer, Bao Alatengqimuge, Lian Hanqing, Song Fushun, Zhang Wen, Zhang Tianji, Bao Xilinqiqige, Bao Tegexibaiyin, B. Siqin, Bao Wuhanqimuge","doi":"10.11648/j.ijpc.20220801.12","DOIUrl":"https://doi.org/10.11648/j.ijpc.20220801.12","url":null,"abstract":"","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78390705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.11648/j.ijpc.20220802.12
Awofisayo Oladoja Abosede, Ologunagba Modupe Oluyemisi, Eseyin Olorunfemi Abraham
{"title":"Effect of the Impact of the Lockdown on Various Sectors in the COVID-19 Era","authors":"Awofisayo Oladoja Abosede, Ologunagba Modupe Oluyemisi, Eseyin Olorunfemi Abraham","doi":"10.11648/j.ijpc.20220802.12","DOIUrl":"https://doi.org/10.11648/j.ijpc.20220802.12","url":null,"abstract":"","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87932943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.11648/j.ijpc.20220801.11
Aminata Pagnimdebsom Nacoulma, M. Compaoré, S. Bakasso, Naamwin-So-Bawfu Romaric Meda, M. Kiendrebeogo
{"title":"Anti-proliferative Effect of Nine Resins from Medicinal Plants of Burkina Faso","authors":"Aminata Pagnimdebsom Nacoulma, M. Compaoré, S. Bakasso, Naamwin-So-Bawfu Romaric Meda, M. Kiendrebeogo","doi":"10.11648/j.ijpc.20220801.11","DOIUrl":"https://doi.org/10.11648/j.ijpc.20220801.11","url":null,"abstract":"","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83509629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-13DOI: 10.11648/J.IJPC.20210705.11
Gabisa Gidisa, Zenebe Wubshet, Negasa Dechasa
Coffee has for centuries played an important role in the Ethiopian economy and represents the main cash crop cultivated by small-scale farmers for social, economic, political and ecological sustainability. The estimated coffee production area in Ethiopia is 561,761 ha. In Ethiopia, coffee berry disease (CBD), coffee wilt disease (CWD) and coffee leaf rust (CLR) are foremost factors in reducing the quantity and quality of coffee in the country. developing disease resistant landrace coffee varieties and boost the yield with their intrinsic cup quality, a multidisciplinary research program has been designed and implemented at Jimma agricultural research center. To meet this objectives, local land race development program of Tepi 88 coffee collections were started in 2015 and 108 coffee accessions were collected and planted in 2016 at Tepi and Gera research sub centre by Jimma Agricultural Research Center. so, 88 coffee accessions were evaluated for their resistance using visual assessment, attached berry test to CBD, visual to scores CLR and laboratory inoculation test to CWD. There were significant differences among the Tepi coffee collections tested for resistance to coffee berry disease. The range was from 0% (T-83/2011) – 98% (T-63/2011) most of Tepi coffee accessions show susceptable reaction for CBD but most of the accessions show resistance reaction at Gera. Coffee collections were also evaluated for their resistance to coffee leaf rust under field condition at Tepi research center. Highly significant difference among coffee cultivars in percent coffee leaf rust severity was observed (Table 1). Coffee leaf rust disease percent severity varied between 0.17% (T-41/2011) – 21.7% (T-11/2011). There existed highly significant difference among cultivars both in percent wilt seedlings death and incubation period). Disease severity and incubation period on Tepi coffee collections varied between 9.33% (T-06/2011) –97.3% (T-21/2011) and 132 -10 days respectively. Based on over all detailed analysis of field evaluation and greenhouse test investigation for major diseases, and their Yield potentials, Nine Tepi coffee accessions were promoted to Variety verification.
{"title":"Evaluation of Tepi and Its Surrounding Coffee Collections Against Major Coffee Diseases at Gera and Tepi","authors":"Gabisa Gidisa, Zenebe Wubshet, Negasa Dechasa","doi":"10.11648/J.IJPC.20210705.11","DOIUrl":"https://doi.org/10.11648/J.IJPC.20210705.11","url":null,"abstract":"Coffee has for centuries played an important role in the Ethiopian economy and represents the main cash crop cultivated by small-scale farmers for social, economic, political and ecological sustainability. The estimated coffee production area in Ethiopia is 561,761 ha. In Ethiopia, coffee berry disease (CBD), coffee wilt disease (CWD) and coffee leaf rust (CLR) are foremost factors in reducing the quantity and quality of coffee in the country. developing disease resistant landrace coffee varieties and boost the yield with their intrinsic cup quality, a multidisciplinary research program has been designed and implemented at Jimma agricultural research center. To meet this objectives, local land race development program of Tepi 88 coffee collections were started in 2015 and 108 coffee accessions were collected and planted in 2016 at Tepi and Gera research sub centre by Jimma Agricultural Research Center. so, 88 coffee accessions were evaluated for their resistance using visual assessment, attached berry test to CBD, visual to scores CLR and laboratory inoculation test to CWD. There were significant differences among the Tepi coffee collections tested for resistance to coffee berry disease. The range was from 0% (T-83/2011) – 98% (T-63/2011) most of Tepi coffee accessions show susceptable reaction for CBD but most of the accessions show resistance reaction at Gera. Coffee collections were also evaluated for their resistance to coffee leaf rust under field condition at Tepi research center. Highly significant difference among coffee cultivars in percent coffee leaf rust severity was observed (Table 1). Coffee leaf rust disease percent severity varied between 0.17% (T-41/2011) – 21.7% (T-11/2011). There existed highly significant difference among cultivars both in percent wilt seedlings death and incubation period). Disease severity and incubation period on Tepi coffee collections varied between 9.33% (T-06/2011) –97.3% (T-21/2011) and 132 -10 days respectively. Based on over all detailed analysis of field evaluation and greenhouse test investigation for major diseases, and their Yield potentials, Nine Tepi coffee accessions were promoted to Variety verification.","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87601625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-15DOI: 10.11648/J.IJPC.20210703.12
Hong-Guang Zhu, Shaoting Li, Man-Yi Wang, D. Wan, Beibei Liu, Zhang Shaopeng, Xulong Ran
Is a commonly used Chinese medicinal herb and is derived from the dried stems of Mahonia bealei (Fort) Carr and Mahonia fortunei (Lindl.) Fedde, as recorded in Chinese Pharmacopoeia (2020). The dried stem of Mahonia confusa Sprague can also be used as a substitute material of Mahoniae caulis in Tujia Nationality residence areas. Alkaloids are thought to be the bioactive chemical constituents in Mahoniae caulis. In this article, a high-performance liquid chromatography method was established for rapid quantitative determination of columbamine, jateorhizine, palmatine and berberine in the three Mahonia plant materials to evaluate and compare their quality. This work provides information for exploration and utilization of potential medicinal resources. In the developed method, a Diamonsil ODS C18 column (5μm, 250mm × 4.6 mm) was used at 30°C. The mobile phase consisted of solution A (acetonitrile) and solution B (50 mm potassium phosphate buffer, pH3.0) with gradient elution at a flow rate of 1.0 mL/min. The detection wavelength was 348 nm. The calibration curves for columbamine, jateorhizine, palmatine and berberine were linear over the range of 0.25–10, 1.50–20, 0.50–10 and 2.5–25 μg/mL, with relative standard deviations of 3.74%, 1.85%, 2.21%, and 1.83%, respectively. Results confirmed the accuracy and repeatability of the method as well as its feasibility for quality control of medicinal materials. The determination results showed that the dried stems of M. bealei and M. fortunei exhibited better quality than those of M. confusa. Nevertheless, the dried stem of M. confusa possessed certain quantities of efficient components.
{"title":"Simultaneous Determination of Four Bioactive Alkaloid Components in the Stems of Three Mahonia Plant Species by HPLC","authors":"Hong-Guang Zhu, Shaoting Li, Man-Yi Wang, D. Wan, Beibei Liu, Zhang Shaopeng, Xulong Ran","doi":"10.11648/J.IJPC.20210703.12","DOIUrl":"https://doi.org/10.11648/J.IJPC.20210703.12","url":null,"abstract":"Is a commonly used Chinese medicinal herb and is derived from the dried stems of Mahonia bealei (Fort) Carr and Mahonia fortunei (Lindl.) Fedde, as recorded in Chinese Pharmacopoeia (2020). The dried stem of Mahonia confusa Sprague can also be used as a substitute material of Mahoniae caulis in Tujia Nationality residence areas. Alkaloids are thought to be the bioactive chemical constituents in Mahoniae caulis. In this article, a high-performance liquid chromatography method was established for rapid quantitative determination of columbamine, jateorhizine, palmatine and berberine in the three Mahonia plant materials to evaluate and compare their quality. This work provides information for exploration and utilization of potential medicinal resources. In the developed method, a Diamonsil ODS C18 column (5μm, 250mm × 4.6 mm) was used at 30°C. The mobile phase consisted of solution A (acetonitrile) and solution B (50 mm potassium phosphate buffer, pH3.0) with gradient elution at a flow rate of 1.0 mL/min. The detection wavelength was 348 nm. The calibration curves for columbamine, jateorhizine, palmatine and berberine were linear over the range of 0.25–10, 1.50–20, 0.50–10 and 2.5–25 μg/mL, with relative standard deviations of 3.74%, 1.85%, 2.21%, and 1.83%, respectively. Results confirmed the accuracy and repeatability of the method as well as its feasibility for quality control of medicinal materials. The determination results showed that the dried stems of M. bealei and M. fortunei exhibited better quality than those of M. confusa. Nevertheless, the dried stem of M. confusa possessed certain quantities of efficient components.","PeriodicalId":14230,"journal":{"name":"International Journal of Pharmacy and Chemistry","volume":"2017 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76358716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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