Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.002
G. Sai Teja, D. Archana, B. Srinu, SK. Abbas Ali, S. Siva Narayana Reddy, SK. Parvez, P. Srinivasa Babu, P. Ravi Sankar
Analytical method validation is a crucial process that provides documented evidence of the suitability, accuracy, specificity
{"title":"A Comprehensive Guide for Analytical Method Validation","authors":"G. Sai Teja, D. Archana, B. Srinu, SK. Abbas Ali, S. Siva Narayana Reddy, SK. Parvez, P. Srinivasa Babu, P. Ravi Sankar","doi":"10.47583/ijpsrr.2023.v82i02.002","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.002","url":null,"abstract":"Analytical method validation is a crucial process that provides documented evidence of the suitability, accuracy, specificity","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.004
Karra Geetha, Sara Akshitha, T. Rama Rao
{"title":"A Review on Colon Drug Delivery Systems","authors":"Karra Geetha, Sara Akshitha, T. Rama Rao","doi":"10.47583/ijpsrr.2023.v82i02.004","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.004","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.009
Pranali P. Holey, Pranali R. Gajbhiye, Anil P. Dewani, Nitin B. Kohale, Nikita P. Aware
Conjunctivitis is characterized by inflammation and swelling of the conjunctival tissue, accompanied by engorgement of the blood vessels, ocular discharge, and pain. There are numerous medicinal plants available in the world to prevent or cure diseases. An ophthalmic problem affects most of the population. Some of these can be treated with antibiotics and steroids but the prolonged use of these drugs has side effects. Many traditional herbal eye drops prepared from many medicinal plants combination, could cure ophthalmic disorders. This review briefly explains the comparative study of herbal drugs and pharmaceutical drugs used in treatment of conjunctivitis. At the present time the pharmaceutical treatment is most popular in market. The reason for its popularity is that in the present world of today the life has become so fast and tedious that only the pharmaceutical treatment suits to the public. The reason being prompt in action highly available easy to take continuous development.
{"title":"Current Updated Review on Prevention and Management of Conjunctivitis: A Comparative Study of Herbal and Pharmaceutical Management","authors":"Pranali P. Holey, Pranali R. Gajbhiye, Anil P. Dewani, Nitin B. Kohale, Nikita P. Aware","doi":"10.47583/ijpsrr.2023.v82i02.009","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.009","url":null,"abstract":"Conjunctivitis is characterized by inflammation and swelling of the conjunctival tissue, accompanied by engorgement of the blood vessels, ocular discharge, and pain. There are numerous medicinal plants available in the world to prevent or cure diseases. An ophthalmic problem affects most of the population. Some of these can be treated with antibiotics and steroids but the prolonged use of these drugs has side effects. Many traditional herbal eye drops prepared from many medicinal plants combination, could cure ophthalmic disorders. This review briefly explains the comparative study of herbal drugs and pharmaceutical drugs used in treatment of conjunctivitis. At the present time the pharmaceutical treatment is most popular in market. The reason for its popularity is that in the present world of today the life has become so fast and tedious that only the pharmaceutical treatment suits to the public. The reason being prompt in action highly available easy to take continuous development.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.024
Muthukumar M, Prabhu R, Rajeev T, Arunpandiyan J, Thaila R, Jayalakshmi B, Senthilraja M
{"title":"Formulation Development of Antimicrobial Nail Lacquer by Transungual Delivery System for the Treatment of Paronychia","authors":"Muthukumar M, Prabhu R, Rajeev T, Arunpandiyan J, Thaila R, Jayalakshmi B, Senthilraja M","doi":"10.47583/ijpsrr.2023.v82i02.024","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.024","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.006
Shubham N. Gharat, Yogeshwary M. Bhongade, Anand D. Sawkare
Fast-dissolving films are developed to overcome difficulty with swallowing which encountered not only in pediatric or geriatric populations but also in the case of handicapped, mentally retarded or bedridden patients. The present study was aimed to formulate fast dissolving film to enhance bioavailability and to avoid first pass effect. The key is to develop successful fast dissolving film by solvent casting method and select right compatible excipients using FTIR and DSC study. The present study describes formulation, optimization and evaluation of fast dissolving film of rizatriptan benzoate in which physical and mechanical parameter such as appearance, thickness, folding endurance, surface pH, disintegration time, in-vitro drug release was evaluated. The formulation was optimized by Box-Behnken design using Design Expert software. The effect of film-forming polymer composition and plasticizer concentration on disintegration time and in-vitro drug release behavior were investigated. The F8 batch was an optimized formulation with less disintegration time of 09 seconds and high in-vitro drug release of 99.58%
{"title":"Formulation and Optimization of Fast Dissolving Film Containing Rizatriptan Benzoate","authors":"Shubham N. Gharat, Yogeshwary M. Bhongade, Anand D. Sawkare","doi":"10.47583/ijpsrr.2023.v82i02.006","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.006","url":null,"abstract":"Fast-dissolving films are developed to overcome difficulty with swallowing which encountered not only in pediatric or geriatric populations but also in the case of handicapped, mentally retarded or bedridden patients. The present study was aimed to formulate fast dissolving film to enhance bioavailability and to avoid first pass effect. The key is to develop successful fast dissolving film by solvent casting method and select right compatible excipients using FTIR and DSC study. The present study describes formulation, optimization and evaluation of fast dissolving film of rizatriptan benzoate in which physical and mechanical parameter such as appearance, thickness, folding endurance, surface pH, disintegration time, in-vitro drug release was evaluated. The formulation was optimized by Box-Behnken design using Design Expert software. The effect of film-forming polymer composition and plasticizer concentration on disintegration time and in-vitro drug release behavior were investigated. The F8 batch was an optimized formulation with less disintegration time of 09 seconds and high in-vitro drug release of 99.58%","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.022
Alifia Hasna Hamidah, Maitsa Nur Maghfira, Ami Tjitraresmi
UV rays not only create unpleasant skin disorders including redness, rough skin, wrinkles, and pigmentation, but they are also responsible for the development of skin malignancies, therefore we need to protect our skin against exposure to UV rays. Carotenoids are metabolites commonly found in plants, often acting as pigments that give yellow to red colors. Carotenoids are predicted to have activity against UV radiation, which can pose risks to the skin, such as sunburn. This systematic literature review was carried out to explore the effects of carotenoids and plants containing carotenoids in protecting skin against UV rays exposures, and to investigate other plants containing carotenoids that were expected to have a potential as a natural UV filter and sunburn prevention. Carotenoids and some plants containing carotenoids are proven as anti-UV and sunburn prevention agents, but further re-examination needs to be done to produce anti-UV preparations with natural active ingredients that are guaranteed for their safety and effective use.
{"title":"The Potency of Natural Carotenoids as a UV-Skin Protection and Sunburn Prevention: Review","authors":"Alifia Hasna Hamidah, Maitsa Nur Maghfira, Ami Tjitraresmi","doi":"10.47583/ijpsrr.2023.v82i02.022","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.022","url":null,"abstract":"UV rays not only create unpleasant skin disorders including redness, rough skin, wrinkles, and pigmentation, but they are also responsible for the development of skin malignancies, therefore we need to protect our skin against exposure to UV rays. Carotenoids are metabolites commonly found in plants, often acting as pigments that give yellow to red colors. Carotenoids are predicted to have activity against UV radiation, which can pose risks to the skin, such as sunburn. This systematic literature review was carried out to explore the effects of carotenoids and plants containing carotenoids in protecting skin against UV rays exposures, and to investigate other plants containing carotenoids that were expected to have a potential as a natural UV filter and sunburn prevention. Carotenoids and some plants containing carotenoids are proven as anti-UV and sunburn prevention agents, but further re-examination needs to be done to produce anti-UV preparations with natural active ingredients that are guaranteed for their safety and effective use.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Systemic and topical nasal decongestants are often used in otorhinolaryngology and general practice to treat acute rhinosinusitis and as an adjuvant in some types of chronic rhinosinusitis. These treatments can occasionally be purchased over-the-counter and can be the target of misuse, which is challenging to prevent. These medicines are particularly effective at quickly reducing nasal congestion. Herbal extract and isolated plant components play a significant role in preparing a traditional Ayurvedic balm to treat nasal congestion and allergic rhinitis. We focus on the modern science of ayurvedic treatment to respiratory therapy. The innovation was Cow Ghee base balm with herbal phytochemicals to prevent respiratory conditions as mentioned earlier. The herbal products are safe for children's use. The medicinal plant plays an important role in the treatment of the common cold, nasal congestion, and chronic conditions like allergic rhinitis. The essential oils are used for the preparation of herbal product-based Ayurvedic balm an invention to replace the petroleum jelly-based treatment.
{"title":"Ghee-Based Balm: A Novel and Innovative Herbal Therapy for Patients with Common Cold, Nasal Congestion, and Allergic Rhinitis","authors":"Sourav Pattanayak, Sagar Sheel, Vikash Kumar, Vinutha Bhat","doi":"10.47583/ijpsrr.2023.v82i02.016","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.016","url":null,"abstract":"Systemic and topical nasal decongestants are often used in otorhinolaryngology and general practice to treat acute rhinosinusitis and as an adjuvant in some types of chronic rhinosinusitis. These treatments can occasionally be purchased over-the-counter and can be the target of misuse, which is challenging to prevent. These medicines are particularly effective at quickly reducing nasal congestion. Herbal extract and isolated plant components play a significant role in preparing a traditional Ayurvedic balm to treat nasal congestion and allergic rhinitis. We focus on the modern science of ayurvedic treatment to respiratory therapy. The innovation was Cow Ghee base balm with herbal phytochemicals to prevent respiratory conditions as mentioned earlier. The herbal products are safe for children's use. The medicinal plant plays an important role in the treatment of the common cold, nasal congestion, and chronic conditions like allergic rhinitis. The essential oils are used for the preparation of herbal product-based Ayurvedic balm an invention to replace the petroleum jelly-based treatment.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"28 21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The objective of the present study was to investigate the Psychopharmacological Activity of the ethanolic and methanolic extract of leaves of Swertia chirayita Roxb. ex Flem. in mice as a part of psychopharmacological screening of this plant, using different in vivo experimental models. The effects of the plant extract ethanolic and methanolic (250 mg/kg and 500 mg/kg respectively) on the central nervous system (CNS) was evaluated by forced swim test, plus maze method, Hole board test and spontaneous motor activity. The results revealed that the ethanolic extract of Swertia chirayita Roxb. ex Flem plant has showed better results as compared to methanolic extract. In the test studied for the Psychopharmacological Activity of ethanolic and methanolic extract of Swertia chirayita Roxb. ex Flem plant, using forced swim test, plus maze method, Hole board test and spontaneous motor activity it was revealed that the ethanolic extract at doses 250 mg/kg and 500mg/kg showed significantly (p<0.05). The overall results suggest that the ethanolic extract of Swertia chirayita Roxb. ex Flem plant contains flavonoids which may possess significant psychopharmacological activity.
{"title":"Psychopharmacological Activity of Chirata","authors":"Sarwar Imam, Vijay Bahadur, Dolly Shukla, Pooja Jaiswal","doi":"10.47583/ijpsrr.2023.v82i02.007","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.007","url":null,"abstract":"The objective of the present study was to investigate the Psychopharmacological Activity of the ethanolic and methanolic extract of leaves of Swertia chirayita Roxb. ex Flem. in mice as a part of psychopharmacological screening of this plant, using different in vivo experimental models. The effects of the plant extract ethanolic and methanolic (250 mg/kg and 500 mg/kg respectively) on the central nervous system (CNS) was evaluated by forced swim test, plus maze method, Hole board test and spontaneous motor activity. The results revealed that the ethanolic extract of Swertia chirayita Roxb. ex Flem plant has showed better results as compared to methanolic extract. In the test studied for the Psychopharmacological Activity of ethanolic and methanolic extract of Swertia chirayita Roxb. ex Flem plant, using forced swim test, plus maze method, Hole board test and spontaneous motor activity it was revealed that the ethanolic extract at doses 250 mg/kg and 500mg/kg showed significantly (p<0.05). The overall results suggest that the ethanolic extract of Swertia chirayita Roxb. ex Flem plant contains flavonoids which may possess significant psychopharmacological activity.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview: The Challenges Involved with Tuberculosis (TB) Treatment based on Nanotechnology and its Impact on Quality of Life","authors":"Yash Srivastav, Akhandnath Prajapati, Madhaw Kumar","doi":"10.47583/ijpsrr.2023.v82i02.012","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.012","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.018
Haseera. N, Baskaran. K, Shalet Varghese, Nirmala Devi. N, Arifa P.P, Rathi MA
{"title":"Antimicrobial Effects of Five Essential Oils Plant on Multidrug Resistant Bacteria Responsible for Urinary Infections","authors":"Haseera. N, Baskaran. K, Shalet Varghese, Nirmala Devi. N, Arifa P.P, Rathi MA","doi":"10.47583/ijpsrr.2023.v82i02.018","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.018","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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