Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.025
A Meena, M. Sasikumar, G. Selvamurugan, P. Senthamizhan, K. Senthamizhselvan, S.Shafeena Begum
{"title":"Review About Pharmacovigilance of Vaccine","authors":"A Meena, M. Sasikumar, G. Selvamurugan, P. Senthamizhan, K. Senthamizhselvan, S.Shafeena Begum","doi":"10.47583/ijpsrr.2023.v82i02.025","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.025","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.47583/ijpsrr.2023.v82i02.020
Dr. Gita Bipin Chandra, Dr. Bindey Kumar, Dr. Swarnika Singh
{"title":"Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and Chronic Kidney Disease: A Randomised Controlled Trial","authors":"Dr. Gita Bipin Chandra, Dr. Bindey Kumar, Dr. Swarnika Singh","doi":"10.47583/ijpsrr.2023.v82i02.020","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i02.020","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136204869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.47583/ijpsrr.2023.v82i01.011
Ayoob Mansoor Akkaparambil, Shehin V Shanavas, Rismi Shirin
Pemphigus vulgaris (PV) is a rare autoimmune disease that is characterized by painful blistering and erosion of the skin and mucous membrane. In the case in hand, a female patient of 44 years was presented with complaints of painful vesicles all over the body with erosions, with no history of fever, headache, or cough. The patient had previously been treated for the lesions over the body, considering them to be chicken pox. The patient was admitted to our hospital without any relief. A skin biopsy was done, a specimen was sent for direct immunofluorescence, and the reports were consistent with pemphigus vulgaris. Blood investigation reports revealed the presence of neutrophilic leucocytosis, elevated CRP, hyponatremia, and hypoalbuminemia. The treatment started with IV Dexamethasone (8mg q 8 hours) along with analgesics, IV fluids, and saline soakings. Secondary infections were managed with antibiotics, antibacterial creams, and other supportive medicines. The patient was provided with sodium supplementation and was advised to eat a protein-rich diet. During the hospital stay, the patient developed foul-smelling discharge from vesicles, and antibiotic treatment was escalated, suspecting pseudomonal infections. Antibiotic ear drops were added to the regimen for painful lesions in the ear and mouth. Artificial tears were added for painful eye lesions. The patient was discharged symptomatically better with sterile blood and pus cultures, healthy skin, and a tapered steroid dose. It is important to consider the nutritional requirements of the patient. Due to the painful nature of oral lesions, PV can result in an impaired nutritional status.
{"title":"A Case on Pemphigus Vulgaris with Superadded Infection, Hypoalbuminemia and Hyponatremia","authors":"Ayoob Mansoor Akkaparambil, Shehin V Shanavas, Rismi Shirin","doi":"10.47583/ijpsrr.2023.v82i01.011","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.011","url":null,"abstract":"Pemphigus vulgaris (PV) is a rare autoimmune disease that is characterized by painful blistering and erosion of the skin and mucous membrane. In the case in hand, a female patient of 44 years was presented with complaints of painful vesicles all over the body with erosions, with no history of fever, headache, or cough. The patient had previously been treated for the lesions over the body, considering them to be chicken pox. The patient was admitted to our hospital without any relief. A skin biopsy was done, a specimen was sent for direct immunofluorescence, and the reports were consistent with pemphigus vulgaris. Blood investigation reports revealed the presence of neutrophilic leucocytosis, elevated CRP, hyponatremia, and hypoalbuminemia. The treatment started with IV Dexamethasone (8mg q 8 hours) along with analgesics, IV fluids, and saline soakings. Secondary infections were managed with antibiotics, antibacterial creams, and other supportive medicines. The patient was provided with sodium supplementation and was advised to eat a protein-rich diet. During the hospital stay, the patient developed foul-smelling discharge from vesicles, and antibiotic treatment was escalated, suspecting pseudomonal infections. Antibiotic ear drops were added to the regimen for painful lesions in the ear and mouth. Artificial tears were added for painful eye lesions. The patient was discharged symptomatically better with sterile blood and pus cultures, healthy skin, and a tapered steroid dose. It is important to consider the nutritional requirements of the patient. Due to the painful nature of oral lesions, PV can result in an impaired nutritional status.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review on Application of Antibacterial Peptides in Food Preservation","authors":"Rajkumar Mondal, Tamalika Chakraborty, Sutripto Ghosh","doi":"10.47583/ijpsrr.2023.v82i01.014","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.014","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In-vitro Anti-inflammatory Activity of Mimosa pudica Against Inhibition of Protein Denaturation and Heat induced Haemolysis Methods","authors":"Rishov Singha, Lakshmi Kanta Kanthal, Suman Pattanayak, Mouli Maiti, Tirthankar Bhuniya, Prithwiraj Maity","doi":"10.47583/ijpsrr.2023.v82i01.008","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.008","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.47583/ijpsrr.2023.v82i01.010
Dr. Kush Nimron, Dr. Sahad P, Dr. Anusha HR, Dr Deepashree S
{"title":"A Review Article of Ceftriaxone + Sulbactam + EDTA Treatment in Multi-Drug Resistance Organism","authors":"Dr. Kush Nimron, Dr. Sahad P, Dr. Anusha HR, Dr Deepashree S","doi":"10.47583/ijpsrr.2023.v82i01.010","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.010","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.47583/ijpsrr.2023.v82i01.013
M Sakthivel, A Swetha, S Thangamaniarasan, S Velmathi, R Vengatesh
{"title":"Review About Transdermal Drug Delivery System","authors":"M Sakthivel, A Swetha, S Thangamaniarasan, S Velmathi, R Vengatesh","doi":"10.47583/ijpsrr.2023.v82i01.013","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.013","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comprehensive Review on Structure Elucidation of General Anaesthetics and Opioid Analgesics as an Element of Modern Pharmaceutical Sciences","authors":"Ananya Das, Abir Sadhukhan, Soumallya Chakraborty, Somenath Bhattacharya, Amitava Roy, Arin Bhattacharjee","doi":"10.47583/ijpsrr.2023.v82i01.016","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.016","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Teratogenesis is derived from Greek word “Terato” which means monster. Teratogenesis results in the development of morphologically abnormal individuals. These may include conditions like intellectual disabilities that don't have any visible structural deformities. This defect is mainly produced by terat ogens which is genesis of physical and functional defect in human’s embryo and fetus. Teratogens have a variety of effects on embryos, including physical deformities, issues with the child's behavioral or emotional development, and a decreased IQ in the child. Teratogens can also have an impact on pregnancies. Physical agents, metabolic circumstances, infections, and finally, medications and chemicals, are the four groups into which teratogens are divided. A few examples of teratogens are prescription medications like thalidomide, environmental poisons like cadmium, and environmental pollutants like pesticides and endocrine disruptors. Viruses, such as the rubella and Zika viruses, physical constriction of the uterus, and a poor diet are additional causes of teratogenesis. This review will examine the drug's history, the scope and kind of the harm it caused, as well as the drug's mechanisms of action, including recent molecular developments and fresh research.
{"title":"A Review on Teratogenesis: Current Perspective","authors":"Renu Sharma, Disha Kesharwani, Sandhya Mishra, Maneesha Kumari","doi":"10.47583/ijpsrr.2023.v82i01.017","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.017","url":null,"abstract":"Teratogenesis is derived from Greek word “Terato” which means monster. Teratogenesis results in the development of morphologically abnormal individuals. These may include conditions like intellectual disabilities that don't have any visible structural deformities. This defect is mainly produced by terat ogens which is genesis of physical and functional defect in human’s embryo and fetus. Teratogens have a variety of effects on embryos, including physical deformities, issues with the child's behavioral or emotional development, and a decreased IQ in the child. Teratogens can also have an impact on pregnancies. Physical agents, metabolic circumstances, infections, and finally, medications and chemicals, are the four groups into which teratogens are divided. A few examples of teratogens are prescription medications like thalidomide, environmental poisons like cadmium, and environmental pollutants like pesticides and endocrine disruptors. Viruses, such as the rubella and Zika viruses, physical constriction of the uterus, and a poor diet are additional causes of teratogenesis. This review will examine the drug's history, the scope and kind of the harm it caused, as well as the drug's mechanisms of action, including recent molecular developments and fresh research.","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comprehensive Review on Structure Elucidation of Local Anesthetic and its Adverse Effects","authors":"Abir Sadhukhan, Ananya Das, Sudip Mukherjee, Anirban Ghosh, Soumallya Chakraborty, Somenath Bhattacharya, Amitava Roy, Arin Bhattacharjee","doi":"10.47583/ijpsrr.2023.v82i01.003","DOIUrl":"https://doi.org/10.47583/ijpsrr.2023.v82i01.003","url":null,"abstract":"","PeriodicalId":14255,"journal":{"name":"International Journal of Pharmaceutical Sciences Review and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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