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Antiallergic potential of a pseudo-stem powder of Musa paradisiaca L. (banana) 香蕉假茎粉的抗过敏作用
Pub Date : 2019-09-20 DOI: 10.15171/ijpni.2019.05
M. Mesa, Abel D. González, L. A. D. L. Luz
Introduction: The use of Musa paradisiaca L. (banana) pseudo-stem powder and juice for the treatment of cold and asthma is part of Cuban traditional medicine. There is not information about the influence of banana stem products on allergic reactions. Therefore, this work was aimed to assess the antiallergic potential of a banana pseudo-stem powder (BPSP) by the use of an experimental model with mice. Methods: Banana stems were collected at Marianao Municipality in Havana. The plant material was ground and filtered and the resulting powder was suspended with acacia 10 mg/mL for experiments. Acute oral toxicity was determined in both sex rats. Female BALB/c mice were sensitized against ovalbumin. Single doses of the powder (60 mg/kg b.w.) or ketotifen (3 mg/kg b.w.) were administered 1 hour before the induction systemic anaphylaxis by i.v. injection of ovalbumin. Moreover, the test product, (0,6; 2; 6 and 20 mg/kg b.w. x day) was given to mice during the immunization period, followed by the induction of systemic anaphylaxis or the measurement of passive cutaneous anaphylaxis titers of mice antisera in rats. Results: There were neither deaths nor any sign of toxicity among the rats treated with banana powder. Unlike ketotifen, a single oral dose of this product was unable to inhibit systemic anaphylaxis in mice. However, a daily oral treatment produced the significant reduction of active and passive anaphylaxis. Conclusion: This work has given the first experimental evidence that a pseudo-stem powder of M. paradisiaca grown in Cuba has an antiallergic potential.
简介:使用芭蕉假茎粉和汁治疗感冒和哮喘是古巴传统医学的一部分。没有关于香蕉茎制品对过敏反应影响的信息。因此,本工作旨在通过小鼠实验模型来评估香蕉假茎粉(BPSP)的抗过敏潜力。方法:在哈瓦那马里亚瑙市采集香蕉茎。将植物材料研磨过滤,得到的粉末用10 mg/mL的金合欢悬浮进行实验。测定了两种性别大鼠的急性口服毒性。雌性BALB/c小鼠对卵清蛋白敏感。在诱导全身过敏反应前1小时静脉注射卵清蛋白,给药单剂量(60 mg/kg体重)或酮替芬(3 mg/kg体重)。并且,测试产品,(0,6;2;在小鼠免疫期间分别给予6和20 mg/kg体重x天),然后诱导全身过敏反应或测定大鼠小鼠抗血清被动皮肤过敏反应滴度。结果:用香蕉粉处理的大鼠没有死亡,也没有任何毒性迹象。与酮替芬不同,单次口服本品不能抑制小鼠的全身过敏反应。然而,每日口服治疗可显著减少主动和被动过敏反应。结论:本研究首次从实验上证实了一种产自古巴的天堂曲假茎粉具有抗过敏作用。
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引用次数: 4
Application of design of experiments in the development of cosmetic formulation based on natural ingredients 实验设计在基于天然成分的化妆品配方开发中的应用
Pub Date : 2019-09-05 DOI: 10.15171/ijpni.2019.04
Gabriela Maria D'Angelo Costa, G. Alves, P. M. Campos
Development of cosmetic formulations based on natural ingredients presents a challenge in order to instability and sensory limitations of raw ingredients. Organogel which is a cold emulsifier and offers refined sensory properties, physical-chemical characteristics and stability could be solved this limitation. The aim of this study is to develop cosmetic formulations by cold process containing natural ingredients and assess through design of experiment (DOE) the influencing factors on the physical-mechanical and sensory properties of these formulations. Physico-mechanical and sensory properties of cosmetic formulations containing natural ingredients obtained by cold process were evaluated. The DOE was performed for the texture analyses. In addition, the influence of natural actives substances in the developed formulations was assessed. The different concentrations of polymers, organogel and active substances influenced the texture profile of the formulations, being the concentration of organogel the most influential factor. The formulation containing sunflower oil, a polymer from a natural source and the highest concentration of organogel influenced the firmness, consistency, cohesiveness and viscosity. The work of shear decreased in the formulation added of the polymer and increased when the formulation was supplemented with active substances. The sensory analysis showed that the formulation based on 5% of organogel, sunflower oil and polymer it was preference for the selected formulation. In conclusion, the application of DOE for the rational development of cosmetic formulations based on natural ingredients led to formulations with physico-mechanical and sensory properties suitable for the application on the skin.
由于原料的不稳定性和感官限制,基于天然成分的化妆品配方的开发提出了挑战。有机凝胶是一种冷乳化剂,具有精细的感官性能、物理化学特性和稳定性,可以解决这一问题。本研究的目的是开发含天然成分的冷加工化妆品配方,并通过实验设计(DOE)评估影响这些配方物理力学性能和感官性能的因素。对冷法制备的天然成分化妆品配方进行了物理力学性能和感官性能评价。用DOE进行了织构分析。此外,还对所研制的制剂中天然活性物质的影响进行了评估。不同浓度的聚合物、有机凝胶和活性物质对配方的织构有影响,其中有机凝胶的浓度对配方的织构影响最大。配方中含有葵花籽油、天然聚合物和最高浓度的有机凝胶,影响了硬度、稠度、黏性和粘度。添加聚合物时,剪切功减小,添加活性物质时,剪切功增大。感官分析表明,以有机凝胶、葵花籽油和聚合物为基础的5%有机凝胶为优选配方。综上所述,利用DOE来合理开发基于天然成分的化妆品配方,可以使配方具有适合皮肤使用的物理力学和感官性能。
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引用次数: 10
Medicinal plant diversity in Aravallis 阿拉瓦利属药用植物多样性
Pub Date : 2019-08-25 DOI: 10.15171/ijpni.2019.03
Satish K. Sharma
Aravallis ranges are one of the very important features of western part of India which runs from Gujarat to Delhi. It traverses in four states viz., Gujarat, Rajasthan, Haryana and Delhi. Maximum part of Aravallis is confined to Rajasthan. As many as 13 wildlife sanctuaries are confined to Aravallis; 10 in Rajasthan, 2 in Gujarat and 1 in Delhi. As many as 3 protected areas are confined to confluence of Aravallis and Vindhyas, all are in Rajasthan. Forest Department, Rajasthan and Foundation for Revitalization of Local Health Traditions, Bangalore jointly has listed 39 species in the "red list of medicinal plants" from Rajasthan state. Most of these listed medicinal plants are present in 16 protected areas. Out of these 16 protected areas, 6 are rich in medicinal plants. Phulwari, Sitamata, Kumbhalgarh, Mt. Abu. Balaram Ambaji and Jassore sanctuaries having 22, 18, 14, 12, 11 and 10 species respectively. The study revels, that southern part of Aravallis is more rich than northern and central Aravallis. The "nals" of southern part of Aravallis are especially rich in medicinal plant diversity
Aravallis山脉是从古吉拉特邦延伸到德里的印度西部的重要特征之一。它穿过四个邦,即古吉拉特邦、拉贾斯坦邦、哈里亚纳邦和德里。Aravallis的大部分被限制在拉贾斯坦邦。阿拉瓦利斯有多达13个野生动物保护区;拉贾斯坦邦10人,古吉拉特邦2人,德里1人。多达3个保护区被限制在Aravallis和Vindhyas的交汇处,都在拉贾斯坦邦。拉贾斯坦邦森林部和班加罗尔当地健康传统振兴基金会共同将拉贾斯坦邦的39种药用植物列入“红色名录”。这些被列入名单的药用植物大多分布在16个保护区。在这16个保护区中,有6个有丰富的药用植物。普瓦里,西塔玛塔,昆巴加尔,阿布山。Balaram Ambaji和Jassore保护区分别有22、18、14、12、11和10种。研究表明,阿拉瓦利斯的南部比北部和中部更富有。阿拉瓦利斯南部的“nals”药用植物多样性尤其丰富
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引用次数: 1
Edible seeds, leaves and flowers as Maya Super Foods: Function and composition 作为玛雅超级食物的可食用种子、叶子和花:功能和成分
Pub Date : 2019-08-20 DOI: 10.15171/ijpni.2019.02
A. Cáceres, S. M. Cruz
Mesoamerica is a megadiverse region where one of the Vavilov center has developed; Guatemala is part of this region, and the heart of the Mayan world. The biodiversity include the traditional utilization of food (grains, fruits, herbs, flowers and rhizomes), flavors, aromas, condiments, dyes and colorants, medicinal and ritual plants, as well as other products from nature. At least 76 vegetal species were developed as food. In this paper it will be presented the information on seeds and grains (Amaranthus cruentus, Brosimum alicastrum, Crescentia alata, Cucurbita pepo, Phaseolus vulgaris, Salvia hispanica, Theobroma cacao, Zea mays), herbs (Amaranthus hybridus, Cnidoscolus aconitifolius, Crotalaria longirostrata, Dysphania ambrosioides, Lycianthes synanthera, Solanum americanum, S. nigrescens, S. wendlandii), and flowers (Cucurbita pepo, Chamedoroea tepejilote, Fernaldia pandurata, Erythrina berteroana, Gliricidia sepium, Yucca elephantipes,) traditionally used as food. Other foods include fruits, rhizomes, tubers and condiments. The functional properties and nutritive composition are described for 22 native seeds, leaves and flowers. In comparison with recognized international herbs, it is demonstrated that some native Mesoamerican herbs have an important nutritious and functional composition. A rich traditional culinary heritage is the way that these foods are consumed. The use of traditional dishes and innovative fusions with Maya Super Foods is recommended for economy improvement of the region as well as health and beauty.
中美洲是一个生物多样性非常丰富的地区,瓦维洛夫中心已经发展起来;危地马拉是这个地区的一部分,也是玛雅世界的中心。生物多样性包括对食物(谷物、水果、草药、花卉和根茎)、香料、香气、调味品、染料和着色剂、药用和仪式用植物以及其他自然产品的传统利用。至少有76种植物被开发为食物。本文将介绍其种子和籽粒(苋菜、凤梨、月牙、葫芦、菜花、鼠尾草、可可、玉米)、草本植物(苋菜、刺毛草、长叶草、凤梨草、山楂草)、花(葫芦、芫荽、龙葵、黑草、文兰草)、花(芫荽、芫荽、黄花菜、黄花菜、黄花菜)、丝兰,象丝兰,传统上用作食物。其他食物包括水果、根茎、块茎和调味品。描述了22种本地种子、叶和花的功能特性和营养成分。与国际上公认的草本植物相比,表明一些中美洲本土草本植物具有重要的营养和功能成分。这些食物的食用方式是一种丰富的传统烹饪遗产。使用传统菜肴和玛雅超级食品的创新融合被推荐用于该地区的经济改善以及健康和美容。
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引用次数: 4
Nagoya Protocol of CBD, Mechanism to Facilitate International Collaborative Development of Plant-Based Products: India a Case Study 生物多样性公约名古屋议定书,促进植物性产品国际合作开发机制:印度案例研究
Pub Date : 2019-08-15 DOI: 10.15171/ijpni.2019.01
Anurudh K. Singh
Man’s search among natural resources for food and other material needed for living, including health, personal care, wellness, and livelihood support have been predominantly plant based. For a long time, biodiversity and genetic resources were considered part of the heritage of mankind and were available without restriction for scientific research and commercial use. Plant diversity predominantly occurred in old world countries with significant associated traditional knowledge about their potential value. However, they were predominantly exploited by the technologically rich countries, earning major commercial benefits under the auspices of intellectual property rights (IPR). This realization led to division of the world into biodiversity rich and technologically rich countries and global discontentment on unfair sharing of benefits accrued from their commercialization. It led to development of Convention on Biological Diversity (CBD), providing nations the sovereign ownership over biological resources found in their territory, controlling access, ensuring community rights, IPR and right for fair and equitable benefit sharing arising from commercialization. In pursuance, it led to development International Treaty on Plant Genetic Resources for Food and Agriculture under FAO in 2001, to regulate access and benefit sharing of genetic resources of major agricultural crops. It was followed by the Nagoya Protocol, another Access and Benefit System (ABS) system in 2010, covering all biological resources to ensure fair and equitable benefits arising from their commercialization. The present article discusses, how fair and transparent provisions Nagoya Protocol can facilitate greater international cooperation in development and use of plant-based phytonutraceutics, phytotherapeutics and phytocosmetics.
人类从自然资源中寻找食物和其他生活所需的物质,包括健康、个人护理、健康和生计支持,主要是基于植物。长期以来,生物多样性和遗传资源被认为是人类遗产的一部分,可以不受限制地用于科学研究和商业用途。植物多样性主要发生在旧大陆国家,这些国家对其潜在价值有着重要的相关传统知识。然而,它们主要被技术发达的国家利用,在知识产权(IPR)的支持下获得重大商业利益。这种认识导致世界分裂为生物多样性丰富的国家和技术丰富的国家,以及全球对不公平分享其商业化所产生的利益的不满。它促成了《生物多样性公约》(CBD)的发展,规定各国对其领土上发现的生物资源拥有主权所有权,控制获取,确保社区权利、知识产权和公平公平地分享商业化产生的利益的权利。在此基础上,粮农组织于2001年制定了《粮食和农业植物遗传资源国际条约》,规范主要农作物遗传资源的获取和惠益分享。紧随其后的是2010年的《名古屋议定书》,这是另一个获取和惠益制度(ABS)系统,涵盖所有生物资源,以确保其商业化产生的公平和公平的惠益。本文讨论了公平和透明的《名古屋议定书》条款如何促进基于植物的植物营养制剂、植物疗法和植物化妆品的开发和使用方面的更大国际合作。
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引用次数: 0
Application of Calahuala (Phlebodium spp) fern complex for the formulation of diverse medicinal and cosmetic products Calahuala (Phlebodium spp)蕨类植物复合物在各种医药和化妆品配方中的应用
Pub Date : 2018-12-29 DOI: 10.15171/IJPNI.2018.11
A. Cáceres, S. M. Cruz
Extracts of the tropical fern Phlebodium complex of Polypodiaceae family, appear to possess beneficial properties for the skin, attributed to the presence of numerous compounds within the extract that have antioxidant and photoprotective properties. Orally administered Phlebodium complex may provide protection against the detrimental photoaging effects of sunlight, can help reduce the frequency and severity of polymorphous light eruption, and is beneficial for the prevention and potential treatment of several aesthetically relevant conditions. The purpose of this review is to describe beneficial role of Phlebodium complex as an adjunct treatment for vitiligo, melasma, and post-inflammatory hyper-pigmentation. Various extracts applied topically or taken orally have shown several beneficial antioxidant, photo-protectant, anti-mutagenic, and immunoregulatory effects. Modern studies have evaluated the efficacy of Phlebodium extracts as a photoprotective agent and for use in several photo-aggravated dermatologic disorders such as polymorphous light eruption, photodermatoses, vitiligo, melasma, psoriasis, atopic dermatitis, and more recently, in minimizing infections in high-performance athletes. It is these multiple mechanisms of action, in combination with a favorable side effect profile, which make Phlebodium complex a promising adjunctive treatment for several dermatologic disorders. Aerial part has proved to exert antioxidant, photo-protective and immunomodulatory activities; extract of fronds is a natural mixture of phytochemicals endowed with powerful antioxidant properties as flavonoids compared to rhizome. Phlebodium fern extract of fronds and rhizome blocked the deleterious effect of UV irradiation in vitro and in vivo as a natural photoprotectant and potential adjuvant to phototherapy of various skin diseases.
水蛭科热带蕨类植物Phlebodium复合体的提取物似乎对皮肤有益,这是由于其提取物中含有许多具有抗氧化和光保护特性的化合物。口服复合静脉注射液可以防止阳光的有害光老化效应,可以帮助减少多形光爆发的频率和严重程度,并且有利于预防和潜在治疗几种与美学相关的疾病。本综述的目的是描述复合体作为白癜风、黄褐斑和炎症后色素沉着的辅助治疗的有益作用。各种局部或口服提取物显示出几种有益的抗氧化、光保护剂、抗诱变和免疫调节作用。现代研究已经评估了白蛉提取物作为光保护剂的功效,并用于几种光加重的皮肤病,如多形性光疹、光性皮肤病、白癜风、黄褐斑、牛皮癣、特应性皮炎,以及最近在减少高性能运动员感染方面的效果。正是这些多种作用机制,再加上良好的副作用,使得铂复合体成为几种皮肤病的有希望的辅助治疗方法。空中部分已被证明具有抗氧化、光保护和免疫调节活性;与根茎相比,叶子提取物是一种天然的植物化学物质混合物,具有强大的抗氧化特性。蕨叶和根茎提取物是一种天然的光保护剂和光疗各种皮肤病的潜在辅助剂,在体外和体内阻断了紫外线照射的有害作用。
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引用次数: 2
Preliminary stability study of dry and glycolic extract of Ginkgo biloba L. incorporated in phytocosmetic formulations 银杏干提取物和乙醇酸提取物在植物美容制剂中的稳定性初步研究
Pub Date : 2018-12-29 DOI: 10.15171/ijpni.2018.08
Lóide Basílio Oton, Marcia G. de Azevedo, J. Falcão
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引用次数: 0
Development and efficacy evaluation of hair care formulations containing vegetable oils and silicone 含有植物油和硅胶的护发配方的开发和功效评价
Pub Date : 2018-12-29 DOI: 10.15171/ijpni.2018.09
M. G. A. Leite, P. M. Maia Campos
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引用次数: 4
Evaluation of phytochemical variations in medicinal plants of Rajasthan 拉贾斯坦邦药用植物化学变异的评价
Pub Date : 2018-12-29 DOI: 10.15171/ijpni.2018.12
P. K. Kasera, A. Soni, Kavita Daiya, A. Sagar
The present study deals with evaluation of phytochemical variations in terms of primary and secondary metabolites in 4 important medicinal plants, viz. Arisaema tortuosum (Whipcord lilly), Corbichonia decumbens (Stone plant), Dipcadi erythraeum (Piazi) and Withania coagulans (Paneer bandth) of the Rajasthan. The primary metabolites such as leaf pigments (Chl. a, Chl. b, total chlorophylls and carotenoids), proline, osmotic potential, total sugars, crude protein, phosphorus and secondary ones like total alkaloids and phenols were estimated during different growth stages/months/seasons in selected plants. Results revealed that in D. erythraeum, except osmotic potential and total sugars, all parameters were showed significant variations. The peak concentrations of total alkaloids and phenols in A. tortuosum were observed during August and October, respectively. In C. decumbens, maximum values of total chlorophylls were recorded during vegetative whereas total sugars and phosphorus in fruiting stage. The maximum values of total chlorophylls in W. coagulans were observed during winter followed by summer and minimum in rainy season. Phosphorus content was reported to be maximum during rainy season.
本文研究了拉贾斯坦邦4种重要药用植物Arisaema tortuosum (Whipcord lilly)、Corbichonia decumbens (Stone plant)、Dipcadi erythraeum (Piazi)和Withania coagulans (Paneer bandth)初级和次级代谢产物的植物化学变化。主要代谢物如叶片色素(Chl。的背影。测定了所选植物在不同生长阶段/月份/季节的总叶绿素和类胡萝卜素B、脯氨酸、渗透势、总糖、粗蛋白质、磷和总生物碱和酚类物质等次生物质含量。结果表明,除渗透势和总糖外,各参数均有显著差异。总生物碱和酚类物质的含量高峰分别出现在8月和10月。总叶绿素在营养期最高,总糖和总磷在结实期最高。凝固剂总叶绿素在冬季最高,夏季次之,在雨季最低。据报道,磷含量在雨季最高。
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引用次数: 2
Effectiveness of Camellia sinensis (L.) Kuntze for treatment of Acne vulgaris stages 0, I and II 山茶的药效研究昆滋治疗寻常性痤疮0、I、II期
Pub Date : 2018-12-29 DOI: 10.15171/ijpni.2018.10
Maria de los Angeles Salcedo Rios, Laurentino Salcedo Aguirre, Carlos Laforcada Ríos
Several studies with Camellia sinensis (L.) Kuntze (syn. Thea sinensis L.) suggest that topical application may be potentially effective for acne, however this effectiveness has not always been demonstrated. The objective of this study was to demonstrate the efficacy of C. sinensis leaves extract for the treatment of acne. A double-blind, randomized, controlled clinical trial was carried out including 60 patients between 18 and 25 years old diagnosed with grade O, I and II acne in whom the clinical evaluation, measurement of sebaceous secretion and hydration were performed, in addition to photographic records. The intervention time was 3 weeks and the follow-up was 3 additional weeks. Patients were selected according to inclusion criteria and divided into two groups by simple randomization. The intervention group received the glycolic extract of C. sinensis as treatment and the control group received a preparation with the same organoleptic characteristics. Both groups used the preparation topically for three weeks. The evaluations and measurements of the study variables were carried out weekly. The application of glycolic extract of C. sinensis showed an adequate control of the sebaceous secretion (P = 0.001) without producing dry skin. The hydration levels were higher in the intervention group in relation to the control group (P = 0.18). It was also observed that the color of the skin is uniform. No side effects were observed. This study demonstrates that the glycolic extract of C. sinensis is effective in the treatment of acne O, I and II.
{"title":"Effectiveness of Camellia sinensis (L.) Kuntze for treatment of Acne vulgaris stages 0, I and II","authors":"Maria de los Angeles Salcedo Rios, Laurentino Salcedo Aguirre, Carlos Laforcada Ríos","doi":"10.15171/ijpni.2018.10","DOIUrl":"https://doi.org/10.15171/ijpni.2018.10","url":null,"abstract":"Several studies with Camellia sinensis (L.) Kuntze (syn. Thea sinensis L.) suggest that topical application may be potentially effective for acne, however this effectiveness has not always been demonstrated. The objective of this study was to demonstrate the efficacy of C. sinensis leaves extract for the treatment of acne. A double-blind, randomized, controlled clinical trial was carried out including 60 patients between 18 and 25 years old diagnosed with grade O, I and II acne in whom the clinical evaluation, measurement of sebaceous secretion and hydration were performed, in addition to photographic records. The intervention time was 3 weeks and the follow-up was 3 additional weeks. Patients were selected according to inclusion criteria and divided into two groups by simple randomization. The intervention group received the glycolic extract of C. sinensis as treatment and the control group received a preparation with the same organoleptic characteristics. Both groups used the preparation topically for three weeks. The evaluations and measurements of the study variables were carried out weekly. The application of glycolic extract of C. sinensis showed an adequate control of the sebaceous secretion (P = 0.001) without producing dry skin. The hydration levels were higher in the intervention group in relation to the control group (P = 0.18). It was also observed that the color of the skin is uniform. No side effects were observed. This study demonstrates that the glycolic extract of C. sinensis is effective in the treatment of acne O, I and II.","PeriodicalId":14291,"journal":{"name":"International Journal of Phytocosmetics and Natural Ingredients","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80709811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Phytocosmetics and Natural Ingredients
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