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2015 19th National Biomedical Engineering Meeting (BIYOMUT)最新文献

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Feature extraction for EEG based emotion prediction applications through chaotic analysis 基于混沌分析的EEG情感预测特征提取
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369444
Suayip Acar, Hamdi Melih Saraoglu, Saime Akdemir Akar
Electroencephalogram (EEG)-based emotion recognition is a rapidly growing field. This paper presents a research study on identifying the changes caused by human emotions in brain signals through EEG records and further examines the availability of chaotic analysis for emotion prediction applications. We designed an efficient presentation including 30 pictures from International Affective Picture System (IAPS) which could stimulate the emotions of happiness, sadness and fear. A group of 20 persons consisting of 12 males and 8 females took place in our research study as subjects voluntarily. In order to acquire the EEG signals under picture induction environment, a total of 30 pictures that might reveal the feelings of happiness, sadness and fear were shown to the volunteer subjects that participated in the study voluntarily. Data acquired from EEG records were analyzed by using chaotic analysis through MATLAB program and two different attributes consisting of "Largest Lyapunov Exponent (LLE)" and "Correlation Dimension" were obtained. The mean values of each attribute that obtained through chaotic analysis were compared by using independent t-test and dependent t-test in SPSS program with 95% confidence interval and a P value of p<;0.05. The independent samples t-test was used to compare the mean values of each attribute relevant to two unrelated groups (Females-Males) and Dependent samples t-test was used to test whether the mean values of two related observations (two observations for per subject) significantly differs from the hypothesized value. Our study shows that chaotic analysis promises hope for future studies.
基于脑电图(EEG)的情绪识别是一个快速发展的领域。本文介绍了一项通过脑电图记录识别人类情绪引起的大脑信号变化的研究,并进一步探讨了混沌分析在情绪预测应用中的可用性。我们设计了一个高效的演示,包括30张来自国际情感图片系统(IAPS)的图片,这些图片可以激发快乐、悲伤和恐惧的情绪。一组由12名男性和8名女性组成的20人自愿参加了我们的研究。为了获取图片诱导环境下的脑电图信号,我们向自愿参与研究的志愿者展示了30张可能反映快乐、悲伤和恐惧情绪的图片。利用MATLAB程序对脑电记录数据进行混沌分析,得到“最大李雅普诺夫指数”和“相关维数”两个不同属性。通过混沌分析得到各属性的均值,采用SPSS程序中的独立t检验和相关t检验进行比较,置信区间为95%,P值为P <;0.05。使用独立样本t检验比较与两个不相关组(female - male)相关的各属性的平均值,使用依赖样本t检验检验两个相关观察值(每个受试者两个观察值)的平均值是否与假设值有显著差异。我们的研究表明,混沌分析为未来的研究带来了希望。
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引用次数: 4
Development, 3D printing and characterization of calcium sulfate based scaffolds for bone tissue engineering 骨组织工程用硫酸钙基支架的开发、3D打印及表征
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369434
B. Aldemir, Serkan Dikici, O. Karaman, H. Oflaz
Clinic applications of bone tissue (BT) transplantation are used widely for treatment of large bone defects. In BT field, development of biomimetic bone tissue scaffolds which have appropriate chemical and mechanical properties for clinic applications is needed. Biomimetic bone tissue scaffolds should be used for bone grafts which are developed with tissue engineering approach to mimic extracellular matrix. Since bone have high percentage of hydroxyapatite, ceramic biomaterials have grand potential to be used as inorganic tissue scaffold. Literature shows that ceramic based scaffolds such as calcium sulphate, β-tricalcium phosphate and hydroxyapatite support cell attachment, can be resorbed by osteoclasts and also degradation rate of the ceramics are in accordance with bone regeneration rate. The most critical step is production of defect matching scaffold in on custom artificial bone applications. Therefore, powder based three dimensional (3D) printing become prominent because of the numerous advantages such as design independency and high controllability of inner and outer structure. Scaffolds were designed by using CAD programs and printed with CaSO4M.5H2O (calcium sulphate hemihydrate) powders by using 3D printing technology. Then mechanical and biological properties of the scaffolds were tested to investigate the usage potential of CaSO4.0.5H2O based 3D printed scaffolds in tissue engineering. Cytotoxicity results showed that 3D printed scaffolds provided a suitable environment for cell culture. As a result, usage of 3D printing technology in production of controllable scaffold production for artificial tissue development has an important potential.
骨组织移植在临床上广泛应用于大型骨缺损的治疗。在BT领域,需要开发具有合适的化学和力学性能的仿生骨组织支架用于临床应用。仿生骨组织支架是利用组织工程方法开发的模拟细胞外基质的骨移植材料。由于骨中羟基磷灰石含量高,陶瓷生物材料作为无机组织支架具有很大的应用潜力。文献表明,硫酸钙、β-磷酸三钙、羟基磷灰石等支持细胞附着的陶瓷基支架可被破骨细胞吸收,且陶瓷的降解速率与骨再生速率一致。在定制人工骨应用中,最关键的一步是缺陷匹配支架的制作。因此,基于粉末的三维打印以其设计独立性和内外结构的高度可控性等诸多优点而变得突出。采用CAD程序设计支架,用CaSO4M打印。5H2O(半水合硫酸钙)粉末采用3D打印技术。然后测试支架的力学性能和生物学性能,探讨CaSO4.0.5H2O基3D打印支架在组织工程中的应用潜力。细胞毒性实验结果表明,3D打印支架为细胞培养提供了良好的环境。因此,将3D打印技术应用于人工组织发育的可控支架生产具有重要的潜力。
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引用次数: 2
The nonconformities of the consumables in sterilization processes and corrective-preventive activities 灭菌过程和纠正预防活动中耗材的不符合项
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369467
M. Sezdi, Nesrin Durmus
Each step in the sterilization process affects the sterilization quality. The shelf life of the sterilized material is directly related with this process. In this paper, a literature study investigating the non-conformities that affect the shelf life of the sterilization unit was presented. Specifically, non-conformities of the consumables used in the sterilization process were examined, corrective and preventive activities were planned.
灭菌过程中的每一步都影响灭菌质量。灭菌物料的保质期与这一工艺直接相关。在本文中,一项文献研究调查了影响灭菌装置的保质期的不符合项。具体来说,对灭菌过程中使用的耗材的不符合项进行了检查,并计划了纠正和预防活动。
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引用次数: 0
Efficient cartilage segmentation in high-field knee MR images with voxel-classification-driven region-growing algorithm 基于体素分类驱动区域生长算法的高场膝关节MR图像软骨分割
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369447
Ceyda Nur Ozturk, S. Albayrak
This paper presents a voxel-classification-driven region-growing algorithm for automatically segmenting the whole femoral, tibial, and patellar cartilage tissues in high-field magnetic resonance (MR) images of the knee joint by taking into consideration systems with limited resources in particular. An abundance of background voxels and high dimensionality of the voxel samples were alleviated via various subsampling techniques and selecting fewer significant features, respectively. Experiments were conducted on 33 MR images obtained from the Osteoarthritis Initiative (OAI) database in three-dimensional (3-D) double echo in the steady state standard (DESS). After processing 10 MR images for training, four training models were generated by Gaussian, uniform, cartilage vicinity correlated (CVC) sparse, and CVC dense subsampling techniques. Then, their effect on the final segmentation accuracies of the cartilaginous compartments of interest on the remaining 23 test MR images was investigated. As a result, the training models of the CVC sparse subsampling technique, which reduced background voxels in weak proportion to their distances to the border cartilage voxels, produced the highest segmentation accuracies on average for all compartments.
本文提出了一种体素分类驱动的区域生长算法,用于自动分割膝关节高场磁共振(MR)图像中的整个股骨、胫骨和髌骨软骨组织,特别是考虑到资源有限的系统。通过不同的子采样技术和选择较少的重要特征,分别缓解了背景体素的丰富性和体素样本的高维性。实验采用稳态标准(DESS)下三维(3-D)双回波的33张来自Osteoarthritis Initiative (OAI)数据库的MR图像。在对10张MR图像进行训练处理后,分别采用高斯、均匀、软骨邻近相关(CVC)稀疏和CVC密集子采样技术生成4种训练模型。然后,研究了它们对剩余23张测试MR图像中感兴趣的软骨隔室的最终分割精度的影响。因此,CVC稀疏子采样技术的训练模型(将背景体素与边界软骨体素的距离按弱比例减少)对所有隔室产生了平均最高的分割精度。
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引用次数: 0
Hand rehabilitation and prosthesis training interface 手部康复与假肢训练界面
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369433
M. E. Sayilgan, E. Kaplanoglu, A. Atasoy, S. Kuchimov, M. Ozkan
In this study, an interface is developed for the EMG reading glove for physical therapy patients. The purpose of the study is to make physiotherapy available anywhere with computer without the need to go to a therapy center. Physical therapist selects the exercises that fit to the user and sends the exercises to the exercise page of the program. User does the exercises using the wearable hand rehabilitation system. Program follows the user's movements, calculate success and generate a report. This program is developed on Visual Studio 2012 and is a continuous project of the "EMG Hand Rehabilitation and Support System". This process consists four phase, first is to make the exercise plan for the user, second is to demonstrate the exercises to the user, third are the readings of the user's hand movements, forth and the last phase is the animation and control.
本研究开发了一种用于物理治疗患者的肌电读数手套接口。这项研究的目的是使物理治疗在任何地方都可以使用电脑,而不需要去治疗中心。物理治疗师选择适合用户的练习,并将练习发送到程序的练习页面。用户使用可穿戴的手部康复系统进行练习。程序跟踪用户的动作,计算成功并生成报告。本程序是在Visual Studio 2012上开发的,是“肌电手康复支持系统”的连续项目。这个过程包括四个阶段,第一阶段是为用户制定锻炼计划,第二阶段是向用户演示练习,第三阶段是读取用户的手部动作,第四阶段是动画和控制。
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引用次数: 2
Quadrature mirror filter bank design using differential evolution algorithm 正交镜滤波器组设计采用差分进化算法
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369446
T. Koza, N. Karaboga
Filter banks are used like as sub band applications and sub band coding in the signal processing. Quadrature Mirror Filter (QMF) is a base filter bank for these applications. In this work, QMF bank designed for specific signal. QMF prototype filter parameters are designed with Differential Evolution Algorithm.
滤波器组在信号处理中用作子带应用和子带编码。正交镜滤波器(QMF)是这些应用的基础滤波器组。在本工作中,针对特定的信号设计了QMF组。采用差分进化算法设计了QMF原型滤波器参数。
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引用次数: 0
Detarmination of patellar T EMG response with the Deep Tendon Reflex grading and tapping force 用深腱反射分级和叩击力测定髌骨T肌电反应
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369465
S. Uslu, Tunca Nuzket, Y. Albayrak, H. Uysal
In the study, Patellar T Reflex has been evaluated with tapping force measurement and Deep Tendon Reflex grading. Tapping force is measured with an electronic tendon hammer which is designed by us also can be used as a trigger system for determination of patellar T response. System was tested in Akdeniz University Medicine Faculty Neurology Department EMG Laboratory. In the study at least ten trace were obtained from 10 subjects and a total of 100 traces evaluations were performed. The experiment group consisted of people with no neurological disorders. The expected impact of the study is presenting the relationship between tendon reflexes that trigged with applied force to the tendon, deep tendon reflex grading and EMG response as quantitative rating. This led to further understanding of the important role that the reflex behavior in the neurological examination. Also, other departments that can use that study explained at results section.
在研究中,髌骨T反射用叩击力测量和深肌腱反射分级来评估。用自行设计的电子腱锤测量叩击力,也可作为触发系统测定髌骨T反应。系统在Akdeniz大学医学院神经内科肌电实验室进行了测试。在研究中,从10名受试者中获得至少10个痕迹,并进行了总共100个痕迹评估。实验组由没有神经系统疾病的人组成。该研究的预期影响是将肌腱受力触发的肌腱反射、深肌腱反射分级和肌电反应之间的关系作为定量评级。这使人们进一步认识到反射行为在神经学检查中的重要作用。其他可以使用该研究的部门也会在结果部分解释。
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引用次数: 2
Wireless bioacoustic sensor system for automatic detection of bowel sounds 用于自动检测肠道声音的无线生物声学传感器系统
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369458
Erdinc Turk, A. Oztas, U. Ulusar, M. Canpolat, Seyfettin Kazanir, M. Yaprak, G. Ogunc, V. Doğru, Orhan Can Canagir
Due to anesthesia loss of gastrointestinal motility is a common situation for patients who underwent abdominal surgery. The aim of this study is to present the bioacoustic sensor system developed for real time detection of recovery of gastrointestinal tract motility by observing bowel sounds and for bowel sound signal analysis. Different than other studies, in this study, in order to be able to attenuate environmental noise, bowel sounds were observed using two microphones. Bowel sounds were observed between 100 Hz and 1 kHz with maximum amplitude of 20mV. The signal was amplified 121 times and final signal amplitude was between 0-2, 4V. Similarly, environmental noise observed by the second microphone was amplified. Both of the signals were digitized using 12 bit analog digital converter of the ZigBee module (JN5139-Z01) and were transferred with wireless connection. With the developed software, spectral and temporal properties were obtained and presented in real-time. Finally, a stethoscope shaped box was designed for easy use of the sensor system.
由于麻醉导致胃肠运动障碍是腹部手术患者的常见情况。本研究的目的是介绍通过观察肠道声音来实时检测胃肠道运动恢复并进行肠道声音信号分析的生物声学传感器系统。与其他研究不同的是,在本研究中,为了能够减弱环境噪声,使用两个麦克风观察肠道声音。肠音在100hz和1khz之间,最大振幅为20mV。信号放大121倍,最终信号幅值在0 ~ 2.4 v之间。同样,第二个麦克风观察到的环境噪声被放大。两个信号均采用ZigBee模块(JN5139-Z01)的12位模数转换器进行数字化处理,并通过无线连接进行传输。利用开发的软件,实时获取并显示了光谱和时间特性。最后,为了便于传感器系统的使用,设计了一个听诊器形状的盒子。
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引用次数: 8
Task related modulation of group independent components of Alzheimer's disease and mild cognitive impairment patients 阿尔茨海默病和轻度认知障碍患者组独立成分的任务相关调节
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369441
Duygu Sahin, Adil Deniz Duru, A. Bayram, B. Bilgiç, T. Demiralp, A. Ademoglu
In our era, while the life span is expanding, neurodegenerative diseases, such as Alzheimer's disease (AD), pose a great threat upon the quality of life. Currently, one of the urgent goals of neuroscientists is to detect AD in its early stages. Since recent treatments and prevention techniques aim at early and presymptomatic stages, studies carried out to present possible biomarkers are of importance. Therefore, in this study, the objective is to check the suitability of the method to the find a distinctive agent for distinguishing AD and mild cognitive impairment (MCI) patients from controls via fMRI data analysis. In order to achieve that, functional connectivity networks are obtained from an optimized auditory oddball task fMRI data via a group ICA approach using temporal concatenation of the subject data. In this analysis, the initial component number is chosen as thirty and eight different network groups are determined from the spatial classification of the components. In this study, for three components (Attentional Network, Sensory-motor Network, Auditory Network), MCI group independent components (ICs) showed stronger modulation for target sounds when compared to standart sounds. Moreover, when compared to AD group, MCI group showed stronger modulation for standart sounds in their Attentional Network component.
在人类寿命不断延长的今天,阿尔茨海默病(AD)等神经退行性疾病严重威胁着人们的生活质量。目前,神经科学家的迫切目标之一是在早期发现阿尔茨海默病。由于最近的治疗和预防技术针对早期和症状前阶段,因此开展研究以提出可能的生物标志物非常重要。因此,在本研究中,目的是通过fMRI数据分析来检查该方法的适用性,以找到一种独特的药物来区分AD和轻度认知障碍(MCI)患者与对照组。为了实现这一目标,通过使用受试者数据的时间串联的组ICA方法,从优化的听觉古怪任务fMRI数据中获得功能连接网络。在本分析中,选取了初始成分数,并根据成分的空间分类确定了38个不同的网络组。在本研究中,对于三个组成部分(注意网络、感觉运动网络、听觉网络),MCI组独立组成部分(ic)对目标声音的调制强于标准声音。此外,与AD组相比,MCI组在其注意网络成分中对标准声音表现出更强的调制。
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引用次数: 0
Investigation of temperature dependent optical activity of α - Glucose α -葡萄糖温度依赖性旋光活性的研究
Pub Date : 2015-11-01 DOI: 10.1109/BIYOMUT.2015.7369460
F. Rahimov, Satlyk Gylyjov, Yusuf Efteli, Y. Ozturk, M. Engin
Glucose is one of the fundamental molecules used by organisms as the energy resource. Blood glucose level track and analysis are of special importance. Recently, most used methods are invasive and painful. For that reason, the development of non-invasive methods will provide many advantages. It has been known that polarisation angle of the light rotates when it pass throught the glucose solution. The optical methods for measure blood glucose level are getting development. In respect to this, it is important to determine optical properties of glucose. In this study, the polarisation rotation angle changes observed in various medium temperatures for in-vitro glucose solution to help blood sugar measurement on diabetes mellitus.
葡萄糖是生物体作为能量来源的基本分子之一。血糖水平的跟踪和分析具有特殊的重要性。目前,大多数使用的方法是侵入性的和痛苦的。因此,非侵入性方法的发展将提供许多优势。我们知道,当光穿过葡萄糖溶液时,其偏振角会发生旋转。光学测量血糖水平的方法正在不断发展。在这方面,确定葡萄糖的光学性质是很重要的。本研究通过观察葡萄糖体外溶液在不同介质温度下的极化旋转角度变化,帮助糖尿病患者测量血糖。
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引用次数: 0
期刊
2015 19th National Biomedical Engineering Meeting (BIYOMUT)
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