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Comparison of General Anesthesia With Spinal Anesthesia on the Quality of Recovery of Patients With Selective Abdominal Hysterectomy in Patients Vising the Largest Women’s Disease Hospital in Northwestern Iran 全麻与脊髓麻醉对伊朗西北部最大的妇女疾病医院选择性腹部子宫切除术患者康复质量的比较
IF 0.7 Q3 Medicine Pub Date : 2020-09-10 DOI: 10.15296/ijwhr.2022.06
M. Mortazavi, M. Parish, A. Dorosti, H. Mohammadipour Anvari
Objectives: The quality of recovery can affect the results of abdominal hysterectomy although this effect is unknown in different methods of anesthesia. Therefore, the present study was conducted to compare general anesthesia (GA) and spinal anesthesia (SA) methods on the quality of the recovery of patients with selective abdominal hysterectomy in patients visiting the largest women’s disease hospital in Northwestern Iran. Materials and Methods: This cross-sectional descriptive study was conducted with the participation of 350 patients with abdominal hysterectomy, who were selected by convenience sampling in Al-Zahra hospital, Tabriz, Iran in 2019. Demographic data, visual pain scale, hemodynamic status, and Aldrete-Kroulik index were recorded for each patient. Data were analyzed using Mann-Whitney, t-test, multivariate regression, and Kolmogorov-Simonov tests in SPSS 20, and P<0.05 was considered statistically significant. Results: In the hemodynamic status, it was found that the SA group was more stable than the GA group but this difference was not significant (P>0.05). Regarding the need for pethidine, the results revealed that the mean (± standard deviation) of the GA group was significantly higher (35.14 ± 10.14) than that of the SA group (20.15 ± 05.25, P=0.039) while there were no significant differences between the two groups in the use of the antiemetic drug (P=0.203). Finally, the evaluations of the quality of recovery showed that the mean±) SD) of the quality of recovery in SA patients was significantly higher compared to GA patients (P=0.015). Conclusions: In general, the quality of recovery was higher in the SA compared to the GA regarding abdominal hysterectomy.
目的:恢复质量会影响腹式子宫切除术的效果,但不同麻醉方式对恢复质量的影响尚不清楚。因此,本研究比较了全身麻醉(GA)和脊髓麻醉(SA)两种麻醉方式对伊朗西北部最大的妇女疾病医院选择性腹式子宫切除术患者康复质量的影响。材料与方法:本横断面描述性研究选取2019年在伊朗大不里兹Al-Zahra医院进行的350例腹性子宫切除术患者。记录每位患者的人口学数据、视觉疼痛量表、血流动力学状态和Aldrete-Kroulik指数。数据分析采用SPSS 20的Mann-Whitney检验、t检验、多元回归和Kolmogorov-Simonov检验,P0.05)。在哌替啶需用方面,GA组的平均值(±标准差)(35.14±10.14)显著高于SA组(20.15±05.25,P=0.039),而两组止吐药物的使用差异无统计学意义(P=0.203)。最后,对恢复质量的评价显示,SA患者的恢复质量的平均值(±)SD)明显高于GA患者(P=0.015)。结论:总的来说,在腹部子宫切除术中,SA组的恢复质量高于GA组。
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引用次数: 3
Migration of Neglected Vaginal Pessaries: A Case Report 被忽视的阴道托部移位一例报告
IF 0.7 Q3 Medicine Pub Date : 2020-08-15 DOI: 10.15296/ijwhr.2021.42
Hyun A Bae, Jeong In Choi, Soo-Ho Chung, J. Sang
Introduction: Vaginal pessaries are commonly used to manage pelvic organ prolapse. Pessaries are usually tolerated although some severe complications can occur in cases of negligence, including vesicovaginal and rectovaginal fistulas. Case Presentation: This is a report of two cases of a neglected vaginal pessary and migration into the rectovaginal space to form a vaginal orifice. Based on examinations, no vaginal pessaries in both cases migrated into the rectum. These pessaries were removed by cutting and rotating movements. Finally, the two patients were discharged after surgery without any complications. Conclusions: Neglected pessaries can lead to serious complications. Thus, patient education, local estrogen treatment, and careful follow-ups are important to prevent such complications.
简介:阴道托通常用于治疗盆腔器官脱垂。子宫托通常是可以忍受的,尽管一些严重的并发症可能发生在疏忽的情况下,包括膀胱阴道瘘和直肠阴道瘘。病例介绍:这是一个报告的两个病例被忽视的阴道子宫托和迁移到直肠阴道空间形成一个阴道口。根据检查,两例患者均无阴道托移位至直肠。这些托托通过切割和旋转运动被移除。两例患者均于术后出院,无任何并发症。结论:忽视子宫托可导致严重并发症。因此,患者教育、局部雌激素治疗和仔细的随访对预防此类并发症很重要。
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引用次数: 1
Social Capital and Related Factors in Women With Gestational Diabetes Mellitus in the North of Iran 伊朗北部妇女妊娠期糖尿病的社会资本及其相关因素
IF 0.7 Q3 Medicine Pub Date : 2020-07-08 DOI: 10.15296/ijwhr.2022.05
J. Ganji, Elham Yousefi Abdolmaleki, M. Afzali, Sedigheh Hasani Moghadam
Objectives: Gestational diabetes mellitus (GDM) is one of the most important medical conditions in high-risk pregnancies. Social capital is one of the essential factors affecting the prevention and control of diabetes and the blood glucose level. The purpose of this study was to investigate the level of social capital and its related factors in GDM in the north of Iran. Materials and Methods: This cross-sectional study was conducted on 212 GDM women who referred to diabetes centers at Razi hospital in Ghaemshahr and Imam Khomeini hospital in Sari in 2019. The women were selected through the convenience sampling method. The data collection tools included Medical-Demographics Information Form and Onyx-Bullen’s Social Capital Questionnaire. Finally, data were analyzed by SPSS (version 25) using descriptive and inferential statistics (multiple regression analysis). Results: The results of this study showed that the mean (standard deviation, SD) of age for GDM women was 29.28 (±5.75). The majority of women (58%) had an academic education. The mean (SD) of social capital was 96.46 (±21.17). Based on the results, a positive and significant correlation was observed between spouse’s education (lower than high school, P=0.001 and academic education, P=0.001), wife’s occupation (employee, P=0.015), spouse’s occupation (employee, P=0.027), and fasting blood sugar (FBS) (P=0.048), as well as a significant negative correlation with 2-hour FBS (P=0.048), 1-hour postprandial glucose level (P=0.001), economic status (dissatisfied, P=0.42), overweight (P=0.009), and obesity (P=0.020). Conclusions: The social capital of GDM women is influenced by various socio-economic factors. According to the findings of this study, women who are economically disadvantaged, overweight, obese, and at high blood sugar levels are at greater risk of rejecting treatment due to low social capital, resulting in poor blood sugar control. Therefore, interventions related to promoting social capital in these groups should be pursued more vigorously, and strengthening of social capital and its influencing factors should be considered as one of the main approaches of health promotion.
目的:妊娠期糖尿病(GDM)是高危妊娠的重要疾病之一。社会资本是影响糖尿病防治和血糖水平的重要因素之一。本研究旨在探讨伊朗北部地区GDM的社会资本水平及其相关因素。材料和方法:这项横断面研究是在2019年对转介到Ghaemshahr Razi医院和Sari伊玛目霍梅尼医院糖尿病中心的212名GDM女性进行的。妇女采用方便抽样法进行选择。数据收集工具包括《医学人口统计信息表》和《Onyx-Bullen社会资本问卷》。最后,使用SPSS (version 25)进行描述性统计和推理统计(多元回归分析)。结果:本研究结果显示,GDM女性年龄的平均值(标准差,SD)为29.28(±5.75)。大多数妇女(58%)接受过学术教育。社会资本均值(SD)为96.46(±21.17)。结果显示,配偶学历(高中以下,P=0.001)、职业(职工,P=0.015)、职业(职工,P=0.027)与空腹血糖(FBS)呈显著正相关(P=0.048),与2小时空腹血糖(P=0.048)、餐后1小时血糖(P=0.001)、经济状况(不满意,P=0.42)、超重(P=0.009)、肥胖(P=0.020)呈显著负相关(P=0.020)。结论:GDM妇女的社会资本受多种社会经济因素的影响。根据本研究的发现,经济条件差、超重、肥胖、高血糖的女性由于社会资本低而拒绝治疗的风险更大,从而导致血糖控制不佳。因此,应更加积极地开展促进这些群体社会资本的相关干预措施,并将加强社会资本及其影响因素作为促进健康的主要途径之一。
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引用次数: 0
Assessment of Strategies for the Reduction of Cesarean Section Rate in Iranian and Foreign Studies: A Narrative Review 伊朗和国外研究降低剖宫产率的策略评估:叙述性回顾
IF 0.7 Q3 Medicine Pub Date : 2020-06-06 DOI: 10.15296/ijwhr.2021.45
Sedigheh Hasani Moghadam, F. Alijani, Nastaran Bagherian Afrakoti, M. Bazargan, J. Ganji
Objectives: This study was conducted aiming at exploring strategies for reducing cesarean section (C-section) in Iranian and foreign studies. Materials and Methods: The present study was carried out using a matrix approach and searching keywords including "Cesarean", "Effective Intervention", and "Cesarean Section Reduction Strategy" to find studies (2000-2019) in databases such as PubMed, SID, Science Direct, Google Scholar, and WHO. Results: CS reduction strategies were classified into 3 categories of psychological, clinical, and structural-policy interventions. The first category supports women throughout labor and childbirth by the midwife, doula, coping skills with fear and pain of labor, changes in the attitudes of service providers and pregnant women. Clinical interventions include vaginal birth after CS, vaginal breech delivery, external cephalic version (ECV) for breech presentation, encouragement of service providers into intermittent auscultation for the fetal heart rate instead of continuous electronic fetal monitoring (EFM), and training of service providers, pregnant woman, and her family. The last category encompassed managing insurance and financial services, receiving one-to-one care and midwifery care throughout active labor, and updating policy of labor induction in post-term pregnancy, as well as women’s admission policy with cervical dilatation of more than 4 cm with regular uterine contractions, active team care in labor, and auditing and feedback. Conclusions: It seems that multi-dimensional interventions are required to reduce the CS rate. Concerning some of the strategies (e.g., ECV), it is suggested that further research should be performed by addressing the limitations and drawbacks of previous studies before applying clinical procedures due to contradictory results.
目的:本研究旨在探讨伊朗和国外研究中减少剖宫产的策略。材料与方法:本研究采用矩阵法,在PubMed、SID、Science Direct、Google Scholar、WHO等数据库中检索“剖宫产”、“有效干预”、“剖宫产减少策略”等关键词,查找2000-2019年的相关研究。结果:CS减少策略分为心理、临床和结构政策干预3类。第一类通过助产士、助产师、应对恐惧和分娩痛苦的技能、服务提供者和孕妇态度的改变,在分娩和分娩过程中为妇女提供支持。临床干预措施包括CS后阴道分娩、阴道臀位分娩、臀位外型(ECV)、鼓励服务提供者间歇听诊胎儿心率而不是连续胎儿电子监测(EFM),以及对服务提供者、孕妇及其家人的培训。最后一类包括管理保险和金融服务,在产程中接受一对一护理和助产护理,更新足月后引产政策,宫颈扩张大于4cm且子宫收缩规律的妇女入院政策,产程中积极的团队护理,审计和反馈。结论:似乎需要多维干预来降低CS率。对于一些策略(如ECV),建议在应用临床程序之前,应进一步研究解决先前研究的局限性和缺点,因为结果相互矛盾。
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引用次数: 1
Effect of Cognitive-Behavioral Therapy Focused on Self-esteem on Fear of Childbirth: A Counseling Approach in Prenatal Care and a Randomized Clinical Trial 以自尊为中心的认知行为疗法对分娩恐惧的影响:产前护理的咨询方法和随机临床试验
IF 0.7 Q3 Medicine Pub Date : 2020-05-17 DOI: 10.15296/ijwhr.2022.07
Maryam Poorjandaghi, K. Vakilian, M. Khorsandi, Mansour Abdi
Objectives: This study aimed to evaluate the effect of cognitive-behavioral therapy focused on self-esteem (CBT-S) on fear of childbirth in nulliparous women. Materials and Methods: In this randomized clinical trial, 24 nulliparous women willing to cesarean section delivery referred to Milad hospital, Tehran, Iran, between July to August 2015 were enrolled with a convenient sampling method. Participants were assigned into two CBT-S and control groups (24 in each group) using randomized blocks of 4. Seven sessions were performed for the CBT-S group, but the control group received routine prenatal classes. FOC was assessed using Harman’s childbirth attitudes questionnaire. The Rosenberg self-esteem scale was used to assess self-esteem at the beginning of the study. Two weeks after the intervention, both groups filled out the FOC and self-esteem questionnaire. Results: The mean score of fear at the end of the study in the CBT-S and control group was significantly different (P=0.001). Also, self-esteem scores increased after intervention in the CBT-S counseling group (4.77 ± 4.07vs -1.79 ± 2.26; P=0.001). Conclusions: This study confirms the importance of the CBT-S approach focusing on self-esteem in reducing FOC.
目的:本研究旨在评价自尊认知行为疗法(CBT-S)对产妇分娩恐惧的影响。材料与方法:采用方便抽样法,选取2015年7 - 8月在伊朗德黑兰Milad医院就诊的24例愿意剖宫产的未产妇女为随机临床试验对象。参与者被随机分为两个CBT-S组和对照组(每组24人),每组4人。CBT-S组进行了七个疗程,但对照组接受常规的产前课程。采用哈曼分娩态度问卷对FOC进行评估。在研究开始时使用罗森博格自尊量表来评估自尊。干预两周后,两组都填写了FOC和自尊问卷。结果:研究结束时,CBT-S组与对照组的恐惧平均得分差异有统计学意义(P=0.001)。干预后,CBT-S咨询组自尊得分明显提高(4.77±4.07vs -1.79±2.26;P = 0.001)。结论:本研究证实了以自尊为中心的CBT-S方法在减少FOC中的重要性。
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引用次数: 0
The Association of Hair Coloring During Pregnancy With Pregnancy and Neonatal Outcomes: A Cross-sectional Study 怀孕期间染发与妊娠和新生儿结局的关系:一项横断面研究
IF 0.7 Q3 Medicine Pub Date : 2020-05-08 DOI: 10.21203/rs.3.rs-24851/v1
M. K. Shishavan, M. Sayyah-Melli, Mohammad Reza Rashid, P. M. Gharabaghi, M. Ghojazadeh, V. Rahmani, Zohreh Tahmasebi
Background: Hair colorant use has spread globally and rapidly in recent years. Concerns have arisen about the safety of hair dyes usage during pregnancy. The primary goal of this study was to examine the association between hair coloring during pregnancy, intrapartum, and neonatal outcomes.Methods: This explorative cross-sectional study was carried out at Talegani Teaching Hospital of Tabriz University of Medical Sciences from Jan 2017 to Dec 2019. Three trained midwives inquired mothers about the hair coloring history on the admission to the labor room and recorded intrapartum, and neonatal outcomes. Chi-Square test of independence with post hoc tests and Logistic regression analysis were used for data analysis. Odds Ratios with a 95% confidence interval and contributing effect sizes were reported. The significance level was set at α ≤ 0.05Results: We studied 2040 women aged 14 to 48 years. Most of the participants (75.24%) dyed their hair during pregnancy, and the majority (62.67%) colored their hair in the third trimester. There was no statistically significant association between hair coloring and neonate 1-minute (p=0.23) and 5-minute Apgar score (p=0.99). The logistic regression model did not confirm a rise in overall neonatal complications (NC) associated with hair coloring at any time during the pregnancy (OR:0.027 p<0.001). Higher rates of Low birth weight (LBW) were seen among those dyed their hair in the preconception period and third trimester compared to the woman who colored their hair in the first and second trimester (p<0.001).Conclusions: We observed associations between hair coloring and LBW, but there were no increased odds for NC. The evidence for recommending hair dye safety during pregnancy is still limited. Perinatal health professionals should advise their patients on possible adverse outcomes and inform them about the uncertainties about hair dyes.
背景:染发剂的使用近年来在全球范围内迅速蔓延。人们开始担心怀孕期间使用染发剂的安全性。本研究的主要目的是研究孕期染发、分娩期染发和新生儿结局之间的关系。方法:本探索性横断面研究于2017年1月- 2019年12月在大不里士医科大学Talegani教学医院进行。三名训练有素的助产士在产妇进入产房时询问其染发史,并记录分娩时和新生儿结局。数据分析采用卡方独立性检验、事后检验和Logistic回归分析。报告了具有95%置信区间的优势比和贡献效应大小。结果:我们研究了2040名年龄在14 ~ 48岁之间的女性。大多数参与者(75.24%)在怀孕期间染发,大多数(62.67%)在妊娠晚期染发。染发与新生儿1分钟(p=0.23)和5分钟Apgar评分(p=0.99)无统计学意义。logistic回归模型未证实妊娠期间任何时间染发相关的新生儿并发症(NC)发生率升高(OR:0.027 p<0.001)。在孕前和妊娠晚期染发的妇女中,低出生体重(LBW)的发生率高于在妊娠早期和中期染发的妇女(p<0.001)。结论:我们观察到染发与LBW之间的关联,但NC的几率没有增加。建议怀孕期间染发剂安全的证据仍然有限。围产期保健专业人员应告知患者可能出现的不良后果,并告知患者染发剂的不确定性。
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引用次数: 0
Effects of Syzygium aromaticum (Clove) Extract on Male Fertility Factors and Oxidative Stress After Torsion/ Detorsion in Adult Male Rats Using Intrauterine Insemination Method 丁香提取物对宫内人工授精成年雄性大鼠扭转/扭转后雄性生殖因子及氧化应激的影响
IF 0.7 Q3 Medicine Pub Date : 2020-03-17 DOI: 10.15296/ijwhr.2022.24
M. Halimi, Tala Pourlak, H. Kalarestaghi, Bita Barghi, M. Moghimian, H. Niazkar, M. Shokoohi
Objectives: The current study was conducted on adult male models to assess the impact of the Syzygium aromaticum (clove) extract on male fertility factors and oxidative stress after torsion/detorsion using the intrauterine insemination (IUI) method. Materials and Methods: This experimental study was performed on 56 adult male Wistar rats including 28 males and 28 females. The male subjects were randomly assigned to four groups of sham (G1), 4 hours of testicular torsion following a surgical torsion/detorsion (TD/G2), TD treated with the clove extract (4 mg/kg, orally/G3) 30 minutes before detorsion, and healthy subjects treated with the clove extract (4 mg/kg/G4). The levels of blood testosterone and some oxidative stress indices were investigated in the testis tissue. In addition, some sperm parameters were evaluated, including the concentration, motility, and morphology of the sperm. Finally, the fertilization potential of adult female rats was assessed through the IUI method. Results: The histological evaluation revealed considerable adverse changes in the G2 in comparison with the sham group. The serum levels of testosterone, and glutathione peroxidase, and superoxide dismutase meaningfully reduced in the testis of rats in the G2. In addition, the malondialdehyde level was significantly higher during the ischemia although all the mentioned changes improved in the treated groups. Nonetheless, the sperm quality and fertility power considerably reduced in the G2 compared to the sham group. Conclusions: The results of the current experimental study demonstrated that the testicular torsion/detorsion has an adverse impact on the testis function and decreases the fertilization potential, and finally, treatment with the clove extract can improve these adverse changes.
目的:本研究采用人工授精(IUI)方法,对成年雄性模型评价丁香提取物对扭转/扭转后雄性生育因子及氧化应激的影响。材料与方法:以56只成年雄性Wistar大鼠为实验对象,其中雄性28只,雌性28只。将男性受试者随机分为4组:假组(G1)、手术扭转/扭转后4小时睾丸扭转组(TD/G2)、扭转前30分钟给予丁香提取物(4mg /kg,口服/G3)、健康组给予丁香提取物(4mg /kg/G4)。测定大鼠睾丸组织血睾酮水平及氧化应激指标。此外,还评估了精子的一些参数,包括精子的浓度、活力和形态。最后,采用人工授精法评价成年雌性大鼠的受精潜力。结果:与假手术组比较,组织学检查显示G2有明显的不良变化。实验组大鼠睾丸中血清睾酮、谷胱甘肽过氧化物酶和超氧化物歧化酶水平显著降低。此外,在缺血期间,丙二醛水平显著升高,尽管治疗组的上述变化均有所改善。尽管如此,与假药组相比,G2组的精子质量和生育能力明显下降。结论:本实验研究结果表明,睾丸扭转/扭曲对睾丸功能有不良影响,降低了受精潜力,丁香提取物可以改善这些不良变化。
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引用次数: 1
Effects of Psycho-education Interventions on Perceived Childbirth Fear and Anxiety by Pregnant Women: A Systematic Review and Meta-analysis 心理教育干预对孕妇分娩恐惧和焦虑的影响:系统回顾和荟萃分析
IF 0.7 Q3 Medicine Pub Date : 2020-01-02 DOI: 10.15296/ijwhr.2021.44
Masomeh Adeli Gargari, Khalil Esmailpour, M. Mirghafourvand, Roghaiyeh Nourizadeh, E. Mehrabi
Objectives: Phobia of natural childbirth is one of the most important and influencing factors leading women to request cesarean sections. The present study aimed to prepare a systematic review and meta-analysis to investigate the type of interventions related to fear of childbirth (FOC). Materials and Methods: The data collection was based on an extensive search of articles related to clinical trials (1990-2019) posted on Google Scholar, Cochran, SID, Magiran, Web of Science, Scopus, and PubMed electronic databases. In general, 109 abstracts were selected after eliminating similar publications. As a result of the qualitative evaluations of these articles, 11 studies were kept for investigation. Results: The studies were categorized into three groups including prenatal education with childbirth counseling, yoga courses, and psychoeducational-based interventions. Based on the meta-analysis, psychoeducational interventions have a significant effect on childbirth fears and anxiety in comparison with the control group (mean difference: 0.85, 95% CI: -1.20–0.45, P < 0.0001, I2 = 82%). Conclusions: Psychologically-based interventions, can creatively play an essential role in reducing the FOC during pregnancy and even childbirth. It can also create a pleasant and traumatic-free experience which is essential for encouraging women to have a natural childbirth.
目的:自然分娩恐惧症是导致产妇选择剖宫产的重要因素和影响因素之一。本研究旨在进行系统回顾和荟萃分析,以调查与分娩恐惧(FOC)相关的干预类型。材料和方法:数据收集基于对Google Scholar、Cochran、SID、Magiran、Web of Science、Scopus和PubMed电子数据库上发表的临床试验相关文章(1990-2019)的广泛搜索。在排除类似出版物后,总共选择了109篇摘要。作为对这些文章进行定性评价的结果,11项研究被保留以供调查。结果:研究分为三组,包括产前教育与分娩咨询、瑜伽课程和基于心理教育的干预。荟萃分析显示,心理教育干预对分娩恐惧和焦虑的影响显著高于对照组(平均差异:0.85,95% CI: -1.20-0.45, P < 0.0001, I2 = 82%)。结论:以心理为基础的干预,可以创造性地在减少妊娠期甚至分娩期间的FOC中发挥重要作用。它还可以创造一种愉快和无创伤的体验,这对于鼓励妇女自然分娩是必不可少的。
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引用次数: 0
Comparison of Menstrual Effluent Vascular Endothelial Growth Factor Immunocytochemistry Expression Between Endometriosis and Non-Endometriosis Patients 子宫内膜异位症与非子宫内膜异位症患者月经流出液血管内皮生长因子免疫细胞化学表达的比较
IF 0.7 Q3 Medicine Pub Date : 2020-01-01 DOI: 10.15296/ijwhr.2021.34
Ruswana Anwar, S. Sunardi, Siti Salima, S. Irianti, B. Purwara, T. Djuwantono, W. Permadi, T. H. Madjid
Objectives: This study aimed to measure the vascular endothelial growth factor (VEGF) expression in menstrual effluent from patients with endometriosis compared to non-endometriosis through immunocytochemical methods. We also measured the degree of pain level, endometrioma cyst size, and infertility status whether it is affected by VEGF expression. Materials and Methods: The present case-control study was conducted in Hasan Sadikin General Hospital, Bandung. Thirty productive-age women diagnosed with endometrioma and 30 productive-age women without endometriosis as the control group were included in this study. Menstrual effluent was taken from the posterior fornix on the second day of menstruation and stained using immunocytochemistry staining for VEGF. Results: The results demonstrated a significant difference between the two study groups in terms of VEGF intensity and histoscore although no difference was found in VEGF distributions between the study groups. The subjects in the endometriosis group had significantly higher VEGF intensity and significantly higher VEGF histoscore compared to the control group. Women with VEGF histoscore more than 6 has 9.33 times risk of developing endometriosis compared to those with lower histoscore. There were no significant correlations between VEGF and pain scale, infertility, and the cyst size. Finally, the cyst size was proportionally related to pain. Conclusions: VEGF distribution and expression in endometriosis women were significantly higher than VEGF levels in non-endometriosis women. Women with menstrual effluent containing higher VEGF levels had more chances of developing endometriosis compared to those with lower VEGF levels. Eventually, larger endometrioma size was proportionally related to higher pain levels in subjects with endometrioma.
目的:本研究旨在通过免疫细胞化学方法比较子宫内膜异位症患者月经流出液中血管内皮生长因子(VEGF)的表达。我们还测量了疼痛程度、子宫内膜瘤囊肿大小和不孕状况是否受VEGF表达的影响。材料与方法:本病例对照研究在万隆市Hasan Sadikin总医院进行。本研究包括30名诊断为子宫内膜异位症的育龄妇女和30名未诊断为子宫内膜异位症的育龄妇女作为对照组。月经第2天取月经后穹窿流出液,免疫细胞化学染色VEGF。结果:结果显示两个研究组在VEGF强度和组织评分方面存在显著差异,但VEGF分布在两个研究组之间没有差异。与对照组相比,子宫内膜异位症组受试者的VEGF强度和VEGF组织评分均显著升高。VEGF组织评分大于6的女性发生子宫内膜异位症的风险是组织评分较低的女性的9.33倍。VEGF与疼痛程度、不孕症、囊肿大小无显著相关性。最后,囊肿大小与疼痛成比例相关。结论:VEGF在子宫内膜异位症患者中的分布和表达明显高于非子宫内膜异位症患者。与VEGF水平较低的女性相比,月经流出物中VEGF水平较高的女性患子宫内膜异位症的几率更高。最终,较大的子宫内膜异位瘤大小与子宫内膜异位瘤患者较高的疼痛程度成比例相关。
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引用次数: 0
Obstetric Risk and Outcomes of Teenage Pregnancy in a University Teaching Hospital, North-Central, Nigeria 尼日利亚中北部一所大学教学医院少女怀孕的产科风险和结果
IF 0.7 Q3 Medicine Pub Date : 2020-01-01 DOI: 10.15296/ijwhr.2021.33
B. Utoo, Unazi Elias Ubah, P. Eka
Objectives: Teenage pregnancy has generated much interest in Obstetrics practice due to increasing risk to the baby and the mother. In this regard, this study was done to ascertain its incidence, obstetric risk, and outcomes. Materials and Methods: This study reviewed the obstetric data sheets of all teenage pregnancies managed between January 2013 and December 2017 at the Benue State University Teaching Hospital, Makurdi, North -Central, Nigeria. Results: Teenage deliveries included 43 cases constituting 2.06% of the total 2084 deliveries within the period. The mean age (SD) was 17.88 (±1.77) years. The commonest antenatal complications were malaria (39.5%), anaemia (37.2%), and hypertension in pregnancy (20.9%). The augmentation of labour was done for 16 parturient mothers (37.2%) and 16.3% had the induction of labour. The caesarean section rate was 16.3% and it was mostly related to obstructed labour (47.1%). In addition, episiotomy was done in 11.6% of parturient mothers and 46.5% had perineal tear. There were 37 live births out of which, 6 cases were neonatal admissions and 6 other cases were perinatal deaths. Finally, the perinatal mortality rate among the teenage deliveries was 139.5 per 1000. Conclusions: The incidence of teenage births was 2.06% with associated obstetric risks and adverse pregnancy outcomes necessitating improved obstetric care during pregnancy and delivery.
目的:由于对婴儿和母亲的风险增加,少女怀孕已经在产科实践中产生了很大的兴趣。在这方面,本研究是为了确定其发生率、产科风险和结局。材料和方法:本研究回顾了2013年1月至2017年12月在尼日利亚中北部马库尔迪贝努埃州立大学教学医院管理的所有少女怀孕的产科数据表。结果:青少年分娩43例,占同期分娩总数2084例的2.06%。平均年龄(SD)为17.88(±1.77)岁。最常见的产前并发症是疟疾(39.5%)、贫血(37.2%)和妊娠期高血压(20.9%)。16名产妇(37.2%)进行了助产,16.3%的产妇进行了引产。剖宫产率为16.3%,主要与难产有关(47.1%)。11.6%的产妇行会阴切开术,46.5%的产妇有会阴撕裂。有37例活产,其中6例是新生儿入院,另外6例是围产期死亡。最后,青少年分娩的围产期死亡率为139.5‰。结论:青少年分娩发生率为2.06%,伴有相关的产科风险和不良妊娠结局,需要改善妊娠和分娩期间的产科护理。
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International Journal of Women's Health and Reproduction Sciences
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