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Multi-omics integration and interactomics reveals molecular networks and regulators of the beneficial effect of yoga and exercise 多组学整合和相互作用揭示了瑜伽和锻炼有益效果的分子网络和调节因子
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_146_21
Manoj Khokhar, S. Tomo, A. Gadwal, P. Purohit
Background: Yoga is a multifaceted spiritual tool that helps in maintaining health, peace of mind, and positive thoughts. In the context of asana, yoga is similar to physical exercise. This study aims to construct a molecular network to find hub genes that play important roles in physical exercise and yoga. Methodology: We combined differentially expressed genes (DEGs) in yoga and exercise using computational bioinformatics from publicly available gene expression omnibus (GEO) datasets and identified the codifferentially expressed mRNAs with GEO2R. The co-DEGs were divided into four different groups and each group was subjected to protein–protein interaction (PPI) network, pathways analysis, and gene ontology. Results: Our study identified immunological modulation as a dominant target of differential expression in yoga and exercise. Yoga predominantly modulated genes affecting the Th1 and NK cells, whereas Cytokines, Macrophage activation, and oxidative stress were affected by exercise. We also observed that while yoga regulated genes for two main physiological functions of the body, namely Circadian Rhythm (BHLHE40) and immunity (LBP, T-box transcription factor 21, CEACAM1), exercise-regulated genes involved in apoptosis (BAG3, protein kinase C alpha), angiogenesis, and cellular adhesion (EPH receptor A1). Conclusion: The dissimilarity in the genetic expression patterns in Yoga and exercise highlights the discrete effect of each in biological systems. The integration and convergences of multi-omics signals can provide deeper and comprehensive insights into the various biological mechanisms through which yoga and exercise exert their beneficial effects and opens up potential newer research areas.
背景:瑜伽是一种多方面的精神工具,有助于保持健康、心灵平静和积极的想法。在体式的背景下,瑜伽类似于体育锻炼。这项研究旨在构建一个分子网络,寻找在体育锻炼和瑜伽中发挥重要作用的枢纽基因。方法:我们使用来自公开基因表达综合(GEO)数据集的计算生物信息学,将瑜伽和锻炼中的差异表达基因(DEGs)结合起来,并用GEO2R鉴定了共差异表达的mRNA。共DEG被分为四组,每组接受蛋白质-蛋白质相互作用(PPI)网络、通路分析和基因本体论。结果:我们的研究确定免疫调节是瑜伽和运动中差异表达的主要靶点。瑜伽主要调节影响Th1和NK细胞的基因,而细胞因子、巨噬细胞激活和氧化应激受运动影响。我们还观察到,虽然瑜伽调节身体两种主要生理功能的基因,即昼夜节律(BHLHE40)和免疫(LBP,T-box转录因子21,CEACAM1),但运动调节参与细胞凋亡(BAG3,蛋白激酶Cα)、血管生成和细胞粘附(EPH受体A1)的基因。结论:瑜伽和运动中基因表达模式的差异凸显了两者在生物系统中的离散效应。多组学信号的整合和汇聚可以对瑜伽和锻炼发挥有益作用的各种生物学机制提供更深入和全面的见解,并开辟潜在的新研究领域。
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引用次数: 1
Effective Stress Management through Meditation: An Electroencephalograph-Based Study 通过冥想有效的压力管理:一项基于脑电图的研究
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_171_21
Ronnie Daniel, Greeshma Sharma, Sushil Chandra
Introduction: Stress among college students is a common health problem that is directly correlated with poor cognitive health. For instance, cognitive mechanisms required for sustenance can be affected due to stress caused by daily mundane events, not necessarily by chronic events. Thus, it becomes essential to manage stress effectively especially for college students. Meditation is one of the useful techniques that facilitates cognitive flexibility and has consequences at the molecular and endocrinal level to treat stress. Objectives: The present study attempts to understand the effect of meditation on the brain waves when participants face stressful events. Methods: A randomized controlled pre-post experimental design was used. Total 18 subjects were randomly assigned to control group and experimental group. Subsequently, Electroencephalograph (EEG) data were recorded during the determination test (DT) before and after the meditation. The Control group underwent relaxation music while the experimental group practiced Sudarshan Kriya Yoga (SKY) (a type of meditation). Non-linear EEG signal processing algorithm was applied to capture dynamics and complexity in brain waves. Results: Results indicated that the efficacy of meditation was reflected with the improved information processing in the brain. Improved performance and reduced errors were reported in DT Scores in the experimental group. Increased complexity of beta band was observed for non-linear features, signifying efficient utilization of cognitive resources while performing the task. Conclusion: Findings implicated the usefulness of the meditation process for effective stress management.
引言:大学生压力是一个常见的健康问题,与认知健康状况不佳直接相关。例如,维持生计所需的认知机制可能会受到日常平凡事件引起的压力的影响,而不一定是慢性事件。因此,有效地管理压力变得至关重要,尤其是对大学生来说。冥想是一种有用的技术,有助于提高认知灵活性,并在分子和内分泌水平上对治疗压力产生影响。目的:本研究试图了解当参与者面临压力事件时,冥想对脑电波的影响。方法:采用随机对照的实验前后设计。将18名受试者随机分为对照组和实验组。随后,在冥想前后的测定测试(DT)期间记录脑电图(EEG)数据。对照组接受放松音乐,实验组练习Sudarshan Kriya瑜伽(一种冥想)。将非线性脑电信号处理算法应用于脑电波的动力学和复杂性捕获。结果:研究结果表明,冥想的效果与大脑信息处理的改善有关。据报道,实验组的DT评分提高了表现,减少了错误。观察到非线性特征的β带复杂性增加,这意味着在执行任务时有效利用了认知资源。结论:研究结果表明冥想过程对有效的压力管理是有用的。
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引用次数: 2
East Meets West in Therapeutic Approaches to the Management of Chronic Pain 东西方在慢性疼痛管理的治疗方法中相遇
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_104_21
E. Hapidou, Ting Huang
Yoga as a holistic principle, not only practice of asanas or poses, integrates all aspects of the self, with biological, mental, intellectual, and spiritual elements. Yoga encompasses the biopsychosocial medical perspective, which regards pain as a dynamic interaction between physiological, psychological, and social factors. The purpose of this perspective article is to compare and contrast psychological practices such as mindfulness meditation, relaxation response (RR), and cognitive behavioral therapy (CBT) with Yoga in their management of chronic pain. The use of these practices is explored through history, literature, and research studies. Results from scientific studies on Yoga show changes in health-related pain outcomes for patients with chronic pain. The key aspects of Yoga, notably relaxation, positive thinking, and mindfulness, are discussed in relation to mindfulness meditation, RR, and CBT.
瑜伽作为一种整体原则,不仅仅是体式或姿势的练习,它整合了自我的各个方面,包括生物、心理、智力和精神元素。瑜伽包含了生物心理社会医学的观点,它认为疼痛是生理、心理和社会因素之间的动态相互作用。这篇透视文章的目的是比较和对比心理学练习,如正念冥想、放松反应(RR)和认知行为疗法(CBT)与瑜伽在治疗慢性疼痛方面的效果。这些实践的使用是通过历史、文学和研究来探索的。关于瑜伽的科学研究结果显示,慢性疼痛患者的健康相关疼痛结果发生了变化。瑜伽的关键方面,特别是放松,积极思考和正念,讨论了正念冥想,RR和CBT的关系。
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引用次数: 1
Integrative Medicine Enhances Motor and Sensory Recovery in Guillain–Barre Syndrome – A Case Study 结合医学促进格林-巴利综合征的运动和感觉恢复-一个案例研究
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_186_21
Akhila Soman, Umesh Chikkanna, K. Ramakrishna, Hemant Bhargav, S. Venkataram, Nishitha Jasti, Shubham Sharma, Velayutham Ganapathy, S. Varambally
Guillain–Barre syndrome (GBS) is a heterogenous group of immune-mediated conditions affecting peripheral nerves. About 40% of patients treated with standard dosage of plasma exchange or intravenous immunoglobulins do not improve in the first 4 weeks following treatment. Add-on treatment from traditional medical approaches such as Yoga therapy and Ayurveda are increasingly being sought for rehabilitation of patients with chronic neurological disorders. The current case study reports the clinical utility of adjunct Yoga and Ayurveda treatment in the treatment of residual symptoms of GBS.
格林-巴利综合征(GBS)是一组影响外周神经的免疫介导的异质性疾病。约40%接受标准剂量血浆置换或静脉注射免疫球蛋白治疗的患者在治疗后的前4周内没有改善。瑜伽疗法和阿育吠陀等传统医学方法的附加治疗越来越多地被用于慢性神经系统疾病患者的康复。目前的病例研究报告了辅助瑜伽和阿育吠陀治疗GBS残余症状的临床效用。
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引用次数: 0
Stretch for Health 健康伸展
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_30_22
T. Srinivasan
Yoga asana practices involve stretching and maintaining a final posture. Maintaining final posture consists of isometric contraction of muscles wherein the muscles work as they carry weight of the body. Thus, stretching and isometrics are inherent in these practices. Irrespective of steadiness or wandering mind of a practitioner, the above components come to play on the neuromuscular system. We know the benefits of the above functions in reasonable details; stretching improves muscle control and isometrics could strengthen the muscles involved.
瑜伽体式练习包括伸展和保持最后的姿势。保持最终姿势包括肌肉的等长收缩,其中肌肉在承受身体重量时发挥作用。因此,拉伸和等距是这些实践中固有的。无论从业者是否稳定或走神,上述成分都会在神经肌肉系统中发挥作用。我们详细了解上述功能的好处;拉伸可以改善肌肉控制,而等长可以增强相关肌肉。
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引用次数: 0
Perceptions about the Benefits and Negative Outcomes of Yoga Practice by Yoga-Naïve Persons: A Cross-sectional Survey 瑜伽天真者对瑜伽练习益处和负面结果的认知:一项横断面调查
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_188_21
S. Sharma, Savita Agnihotri, Niranjan Kala, S. Telles
Background and Objective: Understanding the way nonexercisers view the benefits and barriers to physical exercise helps promote physical exercise. This study reports perceived benefits and negative outcomes of yoga perceived by yoga-naïve persons. Methods: The 2550 yoga-naïve respondents of both sexes (m:f = 2162:388; group mean age ± SD 23.5 ± 12.6 years) participated in a convenience sampling in-person survey conducted to determine the perceived benefits and negative outcomes of yoga. Results: Among 2550 respondents, 97.4% believed yoga practice had benefits. The three most common perceived benefits of yoga were improvement in (i) physical health (39.8%), (ii) cognitive functions (32.8%), and (iii) mental health (20.4%). Among the respondents, 1.4% believed that yoga had negative outcomes. The three most common perceived negative outcomes were (i) apprehension that wrong methods may be harmful (0.24%), (ii) apprehension that excessive practice may harm (0.24%), and (iii) laziness (0.12%). Conclusion: The most common perceived benefit of yoga practice was “improvement in physical health,” with “apprehension that wrong or excessive practice could be harmful” as the most common perceived negative outcomes of yoga.
背景和目的:了解非运动者看待体育锻炼益处和障碍的方式有助于促进体育锻炼。这项研究报告了瑜伽天真者对瑜伽的益处和负面影响。方法:2550名瑜伽天真的男女受访者(m:f=2162:388;组平均年龄±SD 23.5±12.6岁)参加了一项方便抽样的面对面调查,以确定瑜伽的感知益处和负面结果。结果:在2550名受访者中,97.4%的人认为瑜伽练习有好处。瑜伽最常见的三个好处是改善(i)身体健康(39.8%)、(ii)认知功能(32.8%)和(iii)心理健康(20.4%)。在受访者中,1.4%的人认为瑜伽有负面影响。三种最常见的负面结果是:(i)担心错误的方法可能有害(0.24%),以及(iii)懒惰(0.12%)。结论:瑜伽练习最常见的益处是“改善身体健康”,而“担心错误或过度练习可能有害”是瑜伽最常见的负面结果。
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引用次数: 0
Effect of Yoga Lifestyle in Patients with Heart Failure: A Randomized Control Trial 瑜伽生活方式对心力衰竭患者的影响:一项随机对照试验
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_183_21
AshishKumar Jain, CManchanda Subhash, SVivek Bhola, Madan Kushal, Mehta Ashwini, SSawhney Jitendrapal
Background: In spite of significant advances in the management of heart failure (HF), morbidity and mortality remain high. Therefore, there is a need for additional strategies. We did a randomized clinical trial to study effect of yoga in patients with HF in terms of quality of life (QOL), left ventricle ejection fraction (LVEF), C-reactive protein (CRP), and NTproBNP. Materials and Methods: 60 patients with stable HF New York Heart Association Class II with LVEF 30%–40% were randomized into control group (CG) and yoga group (YG). CG received the guideline-based therapy and YG in addition practiced the yoga, one hour daily for 3 months. All patients were assessed for QOL, CRP, NTProBNP, and LVEF at baseline and after 3 months. Results: A significant difference was observed in all four parameters in the YG as compared to the CG (P < 0.01) after 12 weeks. QOL as assessed by Minnesota living with heart failure questionnaire score improved significantly in YG as compared to CG (10 V/s 14, P < 0.001). There was a significant improvement within YG in terms of LVEF (33.4–36.8, P = 0.001), and the percentage change in LVEF was significant between the groups (10% V/s 5%, P = 0.001). NTproBNP also significantly reduced by 69.8% from 755 to 220 Pmol/l in YG as compared to 39.3% in CG (679-406 Pmol/l). CRP decreased by 49.3% (5.36-2.73 mg/L) in YG and 35.8% (5.39-3.45 mg/L) in CG. Conclusion: The result of this pilot study suggests that addition of yoga to guideline-based therapy for HF patients significantly improves QOL, LVEF, and NTProBNP and reduces CRP level. Larger studies are needed to confirm these findings.
背景:尽管心力衰竭(HF)的治疗取得了重大进展,但发病率和死亡率仍然很高。因此,需要额外的策略。我们进行了一项随机临床试验,研究瑜伽对HF患者生活质量(QOL)、左心室射血分数(LVEF)、c反应蛋白(CRP)和NTproBNP的影响。材料与方法:60例LVEF 30% ~ 40%的纽约心脏协会II级稳定HF患者随机分为对照组(CG)和瑜伽组(YG)。CG接受基于指南的治疗,YG在此基础上练习瑜伽,每天一小时,持续3个月。在基线和3个月后评估所有患者的生活质量、CRP、NTProBNP和LVEF。结果:12周后YG 4项指标与CG比较,差异均有统计学意义(P < 0.01)。通过明尼苏达心力衰竭生活问卷评分评估的生活质量,YG组与CG组相比有显著改善(10 V/s 14, P < 0.001)。在YG内,LVEF有显著改善(33.4-36.8,P = 0.001), LVEF的百分比变化在两组之间有显著性差异(10% V/ 5%, P = 0.001)。与对照组的39.3% (679-406 Pmol/l)相比,YG组的NTproBNP也显著降低了69.8%,从755 Pmol/l降至220 Pmol/l。YG组CRP下降49.3% (5.36 ~ 2.73 mg/L), CG组CRP下降35.8% (5.39 ~ 3.45 mg/L)。结论:本初步研究结果表明,在指导治疗的基础上加入瑜伽可显著改善心衰患者的生活质量、LVEF和NTProBNP,并降低CRP水平。需要更大规模的研究来证实这些发现。
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引用次数: 1
Role of Yoga as an Adjunct in the Management of Migraine Headache-Current Status and Future Indications 瑜伽在偏头痛治疗中的辅助作用——现状和未来适应症
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_173_21
D. Nayar, M. Mahapatro, P. Nayar
Migraine headache is a painful, disabling condition afflicting 7% of the population. The long-term effort of coping with a chronic headache disorder predisposes the individual to other psychiatric illnesses, ischemic cerebrovascular disease as well as medicine overuse headache. The use of nonpharmacological methods to reduce the stress and pain associated with headache can improve the overall quality of life and reduce the burden of the disease. To examine the utility of yoga as an adjunct to pharmacological treatment of migraine headache. The review article is based on the secondary literature collected through the Google Scholar database between the years 2010 and 2020. Several themes were identified regarding the burden of migraine/headache and the need for the integration of yoga into the existing healthcare system. Despite the limitations and the need for greater scientific rigor, there have been consistent reports of the beneficial effects of yoga in the reduction of stress, anxiety, depression, and an enhanced quality of life, as well as better pain management in chronic diseases. Studies on the role of yoga in the treatment of migraine have been few in number. They have consistently shown that yoga can be a valuable adjunct to the existing pharmacological interventions in the management of migraine headache. In recent years, the Indian government has made enormous strides in establishing yoga outreach programs throughout the country. The need of the hour is to integrate evidence-based yoga with the wellness centers and noncommunicable diseases treatment plan. It can help to reduce the burden on the existing health care resources.
偏头痛是一种痛苦的致残性疾病,困扰着7%的人口。长期努力应对慢性头痛障碍会使患者容易患上其他精神疾病、缺血性脑血管疾病以及药物过度使用头痛。使用非药物方法来减轻与头痛相关的压力和疼痛,可以提高整体生活质量,减轻疾病负担。研究瑜伽作为偏头痛药物治疗的辅助药物的效用。这篇综述文章基于2010年至2020年间通过谷歌学者数据库收集的二次文献。确定了几个主题,涉及偏头痛/头痛的负担以及将瑜伽纳入现有医疗系统的必要性。尽管存在局限性,需要更严格的科学研究,但有一致的报告表明,瑜伽在减轻压力、焦虑、抑郁、提高生活质量以及更好地管理慢性病疼痛方面具有有益效果。关于瑜伽在治疗偏头痛中的作用的研究数量很少。他们一直表明,瑜伽可以作为治疗偏头痛的现有药物干预的一种有价值的辅助手段。近年来,印度政府在全国范围内建立瑜伽外展项目方面取得了巨大进展。现在的需要是将循证瑜伽与健康中心和非传染性疾病治疗计划相结合。它可以帮助减轻现有医疗资源的负担。
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引用次数: 2
Immediate Effects of OM Chanting on Heart Rate Variability Measures Compared Between Experienced and Inexperienced Yoga Practitioners OM吟唱对有经验和无经验瑜伽练习者心率变异性测量的直接影响
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_141_21
G. Inbaraj, Raghvendra Rao, A. Ram, Sapna K. Bayari, Spoorthi Belur, P. Prathyusha, T. N. Sathyaprabha, K. Udupa
Background: Chanting “OM” is a form of meditation that has numerous health benefits. However, the neurophysiological mechanisms underpinning its effect are surprisingly scarce. The present study aimed to investigate the effect of OM chanting on autonomic modulation, using heart rate variability (HRV), on experienced yoga practitioners and yoga naïve persons. Methods: This prospective study included 19 yoga practitioners (9 females and 10 males; group mean age ± standard deviation [SD]; 25.9 ± 3.2 years) and 17 yoga naïve persons (8 females and 9 males; group mean age ± SD; 24.8 ± 3.6 years) of both sexes and similar age range. Both the groups were assessed for HRV indices (time and frequency domain measures) before and after loud OM chanting for 5 min. Results: Baseline comparison using Mann–Whitney U test between groups showed yoga practitioners had significantly increased high frequency (HF) power (P < 0.029) than nonyoga practitioners, signifying a state of tranquility before the chanting of OM. After 5 min of loud chanting of OM, a comparison between groups assessed using Wilcoxon Signed Ranks test revealed: HF Power, a component of the parasympathetic nervous system, was further amplified with a significantly increase (P < 0.001) in the yoga practitioners group compared to nonyoga practitioners. Furthermore, this increase in HF power was positively correlated with the years of experience in yoga. Conclusion: The present study showed that a brief chanting of OM (5 min) might enhance parasympathetic nervous system activity, promote relaxation, and provide calmness. Further, this experience may be achieved effectively in individuals experienced in yoga than nonyoga practitioners.
背景:吟唱“OM”是一种冥想形式,对健康有很多好处。然而,支撑其作用的神经生理学机制却出奇地稀少。本研究旨在利用心率变异性(HRV)研究OM吟唱对有经验的瑜伽练习者和瑜伽天真者自主调节的影响。方法:这项前瞻性研究包括19名瑜伽练习者(9名女性和10名男性;组平均年龄±标准差[SD];25.9±3.2岁)和17名瑜伽天真者(8名女性和9名男性;群平均年龄±SD;24.8±3.6岁),他们的性别和年龄范围相似。在大声唱OM 5分钟前后,对两组的HRV指数(时域和频域测量)进行了评估。结果:使用Mann–Whitney U检验对两组进行的基线比较显示,瑜伽练习者的高频(HF)功率比非瑜伽练习者显著增加(P<0.029),这表明在唱OM之前处于平静状态。大声呼喊OM 5分钟后,使用Wilcoxon Signed Ranks测试评估的各组之间的比较显示:与非瑜伽练习者相比,瑜伽练习者组的副交感神经系统组成部分HF功率进一步放大,显著增加(P<0.001)。此外,高频功率的增加与多年的瑜伽经验呈正相关。结论:短诵OM(5分钟)可增强副交感神经系统的活动,促进放松,提供平静。此外,与非瑜伽练习者相比,有瑜伽经验的人可以有效地获得这种体验。
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引用次数: 7
Cerebrovascular Dynamics Associated with Yoga Breathing and Breath Awareness 与瑜伽呼吸和呼吸意识相关的脑血管动力学
IF 1.6 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_179_21
Ankur Kumar, Niranjan Kala, S. Telles
Aims: Breath frequency can alter cerebral blood flow. The study aimed to determine bilateral middle cerebral arterial hemodynamics in high-frequency yoga breathing (HFYB) and slow frequency alternate nostril yoga breathing (ANYB) using transcranial Doppler sonography. Methods: Healthy male volunteers were assessed in two separate trials before, during, and after HFYB (2.0 Hz for 1 min, n = 16) and ANYB (12 breaths per minute for 5 min, n = 22). HFYB and ANYB were separately compared to breath awareness (BAW) and to control sessions. Statistical Analysis: The data were analyzed using repeated-measures ANOVA with Bonferroni adjusted post hoc tests. Results: During HFYB there was a decrease in end-diastolic velocity (EDV) and mean flow velocity (MFV) (P < 0.01 for left and P < 0.05 for right middle cerebral arteries; MCA) with an increase in pulsatility index (PI) for the right MCA (P < 0.05). During ANYB, there was a bilateral decrease in peak systolic velocity (P < 0.05 for left and P < 0.01 for right MCA), EDV (P < 0.01) and MFV (P < 0.01 for left and P < 0.001 for right MCA) and an increase in PI (P < 0.01). During BAW of the two sessions there was a decrease in lateralized flow and end-diastolic velocities (P < 0.05) and an increase in PI (P < 0.05). Conclusions: Changes in peak flow velocities and pulsatility indices during and after HFYB, ANYB, and BAW suggest decreased cerebrovascular blood flow and increased flow resistance based on different mechanisms.
目的:呼吸频率可以改变脑血流量。本研究旨在使用经颅多普勒超声测定高频瑜伽呼吸(HFYB)和慢速交替鼻孔瑜伽呼吸(ANIB)中双侧大脑中动脉的血流动力学。方法:在HFYB(2.0Hz,持续1分钟,n=16)和ANYB(每分钟12次呼吸,持续5分钟,n=22)之前、期间和之后,对健康男性志愿者进行两项单独的试验评估。HFYB和ANYB分别与呼吸意识(BAW)和对照组进行比较。统计分析:使用重复测量方差分析和Bonferroni调整后的事后检验对数据进行分析。结果:在HFYB期间,左大脑中动脉舒张末期流速(EDV)和平均流速(MFV)降低(P<0.01,右大脑中动脉;MCA),右MCA搏动指数(PI)升高(P<0.05),EDV(P<0.01)和MFV(左MCA<0.01,右MCA<0.001)和PI升高(P<0.05),BAW提示脑血管血流量减少,血流阻力增加。
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引用次数: 0
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International Journal of Yoga
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