Pub Date : 2021-02-03DOI: 10.22038/IJN.2021.52933.1961
Mohamed Ashraf Eldondity, R. Arafa, S. Ameen, Neveen Tawfeek Abed
Background: Jaundice is a common problem in neonates. Patients undergoing phototherapy need close follow-up of their serum bilirubin levels to determine the treatment response.Objective: To compare between transcutaneous bilirubin measurements (TCB) from covered skin area during phototherapy and total serum bilirubin (TSB) levels.Study design: This prospective observational study included thirty full-term neonates with indirect hyperbilirubinemia requiring phototherapy. We covered a part of the skin (forehead and sternum) in each neonate by using BiliEclipse photo opaque patch and used this covered site to measure TCB during phototherapy to compare it with TSB. Both TSB and TCB estimation were performed from icteric newborns before, at 24 and 48 hours of exposure to phototherapy Results: There was no significant difference between TSB, forehead TCB and sternum TCB before phototherapy and no significant difference between TSB, covered forehead & sternum TCB at 24 hours and 48hours of starting phototherapy. There was highly significant positive correlation between TSB, covered forehead and sternum TCB during phototherapy. No significant difference in both covered forehead and sternum TCB according to different used TCB devices. Conclusion: Measurement of TCB from covered area of skin during phototherapy using transcutaneous bilirubinmeters is reliable method to assess TSB in full term neonates and could lead to a reduction in blood sampling and its complications.
{"title":"Covered Skin Bilirubin Measurement During Phototherapy In Comparison With Total Serum Bilirubin In Full Term Neonates","authors":"Mohamed Ashraf Eldondity, R. Arafa, S. Ameen, Neveen Tawfeek Abed","doi":"10.22038/IJN.2021.52933.1961","DOIUrl":"https://doi.org/10.22038/IJN.2021.52933.1961","url":null,"abstract":"Background: Jaundice is a common problem in neonates. Patients undergoing phototherapy need close follow-up of their serum bilirubin levels to determine the treatment response.Objective: To compare between transcutaneous bilirubin measurements (TCB) from covered skin area during phototherapy and total serum bilirubin (TSB) levels.Study design: This prospective observational study included thirty full-term neonates with indirect hyperbilirubinemia requiring phototherapy. We covered a part of the skin (forehead and sternum) in each neonate by using BiliEclipse photo opaque patch and used this covered site to measure TCB during phototherapy to compare it with TSB. Both TSB and TCB estimation were performed from icteric newborns before, at 24 and 48 hours of exposure to phototherapy Results: There was no significant difference between TSB, forehead TCB and sternum TCB before phototherapy and no significant difference between TSB, covered forehead & sternum TCB at 24 hours and 48hours of starting phototherapy. There was highly significant positive correlation between TSB, covered forehead and sternum TCB during phototherapy. No significant difference in both covered forehead and sternum TCB according to different used TCB devices. Conclusion: Measurement of TCB from covered area of skin during phototherapy using transcutaneous bilirubinmeters is reliable method to assess TSB in full term neonates and could lead to a reduction in blood sampling and its complications.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87239265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.22038/IJN.2021.51741.1941
T. Hamid, D. A. Latif, Ahmed H Bakeer, A. Ibrahim, Khaled Nasef
Background: Some of the neonatal intensive cares (NICUs) partially lack the standard protocols for controlling noise and light. The NICU’s healthy physical environment is crucial for continued normal development of preterm neonates. We aimed to examine the physiological changes (including heart rate, respiratory rate, blood pressure, temperature, and oxygen saturation) induced by noise and ordinary light which often exist in NICUs in a sample of preterm neonates admitted in the growing room due to their low-birth weights.Subjects and methods: This study included 100 preterm neonates, fifty neonates exposed to noise which is often induced in the high-risk NICU and fifty neonates exposed to cyclical light.Results: During noise exposure, neonates in the growing room showed significant increase in the heart rate, respiratory rate, systolic and diastolic blood pressure in addition to a significant decrease in oxygen saturation in the first and second days in the NICU. Moreover, neonates exposed to dim light showed significant decrease in the heart rate, respiratory rate, systolic and diastolic blood pressure in addition to a significant increase in oxygen saturation compared to those exposed to ordinary light in the first and second days. However, body temperature did not show any significant change with noise or light exposure either in the first day or in the second day. Conclusions: This study showed that the exposure to excessive light and noise was associated with significant changes of vital signs in preterm neonates. In addition, the study highlighted the inadequacy of the current conditions in a sample of Egyptian NICUs for ideal neonatal care. In order to create a favorable environment to help better growth and prevent prematurity complications, more attention to the care conditions of infants in the Egyptian NICUs is recommended.
{"title":"The Effect of Light and Noise on Physiological Parameters in a Sample of Preterm Neonates in the Neonatal Intensive Care of Cairo University Teaching Hospital","authors":"T. Hamid, D. A. Latif, Ahmed H Bakeer, A. Ibrahim, Khaled Nasef","doi":"10.22038/IJN.2021.51741.1941","DOIUrl":"https://doi.org/10.22038/IJN.2021.51741.1941","url":null,"abstract":"Background: Some of the neonatal intensive cares (NICUs) partially lack the standard protocols for controlling noise and light. The NICU’s healthy physical environment is crucial for continued normal development of preterm neonates. We aimed to examine the physiological changes (including heart rate, respiratory rate, blood pressure, temperature, and oxygen saturation) induced by noise and ordinary light which often exist in NICUs in a sample of preterm neonates admitted in the growing room due to their low-birth weights.Subjects and methods: This study included 100 preterm neonates, fifty neonates exposed to noise which is often induced in the high-risk NICU and fifty neonates exposed to cyclical light.Results: During noise exposure, neonates in the growing room showed significant increase in the heart rate, respiratory rate, systolic and diastolic blood pressure in addition to a significant decrease in oxygen saturation in the first and second days in the NICU. Moreover, neonates exposed to dim light showed significant decrease in the heart rate, respiratory rate, systolic and diastolic blood pressure in addition to a significant increase in oxygen saturation compared to those exposed to ordinary light in the first and second days. However, body temperature did not show any significant change with noise or light exposure either in the first day or in the second day. Conclusions: This study showed that the exposure to excessive light and noise was associated with significant changes of vital signs in preterm neonates. In addition, the study highlighted the inadequacy of the current conditions in a sample of Egyptian NICUs for ideal neonatal care. In order to create a favorable environment to help better growth and prevent prematurity complications, more attention to the care conditions of infants in the Egyptian NICUs is recommended.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84520757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-10DOI: 10.22038/IJN.2021.51558.1917
Natiqotul Fatkhiyah, Sri Rejeki, Dwi Atmoko
Background: Complication during pregnancy is one of the variables increasing the maternal death rate. To reduce or prevent maternal and perinatal morbidity and mortality, an Antenatal Care Visit (ANC) was implemented. ANC visit is the Pregnancy Monitoring which is not only intended to inspect the health of the mother in general including complications of pregnancy, but also to prepare for a well-born baby and a healthy mother. Therefore, adherence to ANC is important. In this case, the study aimed to determine the maternal determinant variables related to adherence to ANC.Method: This study was drawn into a cross-sectional study with an analytical approach. The number of research respondents was 30 pregnant women who are in the third trimester. The research design indicates the correlation between variables. A univariate data was used for the analysis with variables of mother’s age, parity, and pregnancy diagnosis. While the bivariate analysis was performed with Fisher’s exact test. The study was conducted in Slawi Primary Health Centre, Indonesia.Results: The results showed that pregnant women who regularly did ANC are 86.67%. According to maternal determinants, the results show that there is a correlation between ages and ANC because the p-value is 0.02, also the correlation between parity and ANC with p-value 0.04. However, there is no correlation between pregnancy diagnoses and ANC because the p-value is 0.08.Conclusion: There are correlations between age and parity to ANC, but no correlation between pregnancy diagnosis and ANC.
{"title":"Analysis of Variables Influencing the Antenatal Care Visit in Slawi Primary Health Center, Indonesia","authors":"Natiqotul Fatkhiyah, Sri Rejeki, Dwi Atmoko","doi":"10.22038/IJN.2021.51558.1917","DOIUrl":"https://doi.org/10.22038/IJN.2021.51558.1917","url":null,"abstract":"Background: Complication during pregnancy is one of the variables increasing the maternal death rate. To reduce or prevent maternal and perinatal morbidity and mortality, an Antenatal Care Visit (ANC) was implemented. ANC visit is the Pregnancy Monitoring which is not only intended to inspect the health of the mother in general including complications of pregnancy, but also to prepare for a well-born baby and a healthy mother. Therefore, adherence to ANC is important. In this case, the study aimed to determine the maternal determinant variables related to adherence to ANC.Method: This study was drawn into a cross-sectional study with an analytical approach. The number of research respondents was 30 pregnant women who are in the third trimester. The research design indicates the correlation between variables. A univariate data was used for the analysis with variables of mother’s age, parity, and pregnancy diagnosis. While the bivariate analysis was performed with Fisher’s exact test. The study was conducted in Slawi Primary Health Centre, Indonesia.Results: The results showed that pregnant women who regularly did ANC are 86.67%. According to maternal determinants, the results show that there is a correlation between ages and ANC because the p-value is 0.02, also the correlation between parity and ANC with p-value 0.04. However, there is no correlation between pregnancy diagnoses and ANC because the p-value is 0.08.Conclusion: There are correlations between age and parity to ANC, but no correlation between pregnancy diagnosis and ANC.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86700877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-10DOI: 10.22038/IJN.2021.45816.1764
Shiney Easo, N. A. Naqeeb, A. Tolba, A. John, Ayman A. Azab, Sarah Ata, Sonia D'souza, Daisy Josphine Lobo
Background: Extreme Low birth infants are vulnerable to a series of morbidities like LOS, CLD, IVH, NEC which result in prolonged hospitalization. The value of breastmilk in reducing the severity of these morbidities have been studied. The use of mothers’ own colostrum early after birth by oropharyngeal route in small frequent doses is suggested to have immunomodulatory effect through OLFAT and possible reduction in morbidities.Objective: The study is a single centre, double blinded randomized controlled trial to assess the effectiveness of oral therapy with colostrum or breast milk on clinical outcomes in preterm babies less than 33 weeks’ gestation. Methods: 48 babies were randomly assigned to receive 0.2 ml of own mother’s colostrum, breast milk; or sterile water by oropharyngeal route every 4 hours, until independent feeding at breast or bottle was achieved. Eligibility included inborn preterm babies less than 33 weeks and below 1500 grams. Exclusion criteria were congenital anomalies, congenital viral infection, out born babies, babies of single mothers with unknown partners (mothers were incarcerated based on the country’s laws and breast milk was unavailable), confirmed immunodeficiency disorder, inborn error of metabolism, parental refusal to participate, and preterm babies with overt bleeding.The clinical outcomes studied were NEC, Culture-proven LOS, IVH, ROP, CLD, Jaundice requiring phototherapy, mortality, age at discharge home and length of hospital stay. Results: OIT with colostrum or Breastmilk did not show a statistical improvement in the clinical outcomes between the two groups or length of hospital stay. Conclusion: Oral therapy with colostrum is an alternative method of providing mothers’ milk for neonates who are kept nil per oral that could allow mothers to engage in the infants’ care in the early critical period of their life.
{"title":"A Randomized Controlled Trial of Oral Immunotherapy Therapy with Colostrum or Breast milk and Clinical Outcomes among Preterm Babies.","authors":"Shiney Easo, N. A. Naqeeb, A. Tolba, A. John, Ayman A. Azab, Sarah Ata, Sonia D'souza, Daisy Josphine Lobo","doi":"10.22038/IJN.2021.45816.1764","DOIUrl":"https://doi.org/10.22038/IJN.2021.45816.1764","url":null,"abstract":"Background: Extreme Low birth infants are vulnerable to a series of morbidities like LOS, CLD, IVH, NEC which result in prolonged hospitalization. The value of breastmilk in reducing the severity of these morbidities have been studied. The use of mothers’ own colostrum early after birth by oropharyngeal route in small frequent doses is suggested to have immunomodulatory effect through OLFAT and possible reduction in morbidities.Objective: The study is a single centre, double blinded randomized controlled trial to assess the effectiveness of oral therapy with colostrum or breast milk on clinical outcomes in preterm babies less than 33 weeks’ gestation. Methods: 48 babies were randomly assigned to receive 0.2 ml of own mother’s colostrum, breast milk; or sterile water by oropharyngeal route every 4 hours, until independent feeding at breast or bottle was achieved. Eligibility included inborn preterm babies less than 33 weeks and below 1500 grams. Exclusion criteria were congenital anomalies, congenital viral infection, out born babies, babies of single mothers with unknown partners (mothers were incarcerated based on the country’s laws and breast milk was unavailable), confirmed immunodeficiency disorder, inborn error of metabolism, parental refusal to participate, and preterm babies with overt bleeding.The clinical outcomes studied were NEC, Culture-proven LOS, IVH, ROP, CLD, Jaundice requiring phototherapy, mortality, age at discharge home and length of hospital stay. Results: OIT with colostrum or Breastmilk did not show a statistical improvement in the clinical outcomes between the two groups or length of hospital stay. Conclusion: Oral therapy with colostrum is an alternative method of providing mothers’ milk for neonates who are kept nil per oral that could allow mothers to engage in the infants’ care in the early critical period of their life.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89800445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-10DOI: 10.22038/IJN.2021.52842.1948
S. Kalyanshettar, S. Charki
COVID-19 in neonates is an emerging challenge to pediatricians. Majority of the neonates with COVID-19 described so far are suspected to be due to postnatal transmission. Vertical transmission has been reported in 2 case cohort studies till date.32 weeks preemie born to primigravida mother with history of Preterm premature rupture of membranes (PPROM) was admitted in NICU with birth weight of 2 kg in view of respiratory distress. Neonate developed arterial thrombosis on first day of life and subsequent gangrene of right foot and tested positive for serology and rtPCR of SARS-CoV-2 with elevated inflammatory markers (CRP, D Dimer, Serum Ferritin, Lactate dehydrogenase). The mother was asymptomatic and hence was not tested for SARS-CoV-2 antenatally. After the confirmation in neonate, mother was also tested for SARS-CoV-2 and she tested positive by rtPCR as well as serology.This rare presentation calls for further research in transmission patterns either antenatally or vertical transmission. This report emphasizes the possibility of vertical transmission of COVID-19 in neonates from asymptomatic mother, with significant, early onset neonatal infection in the form of thrombosis.
{"title":"Arterial Thrombosis and Gangrene In A Neonate With COVID-19 - A Case Report.","authors":"S. Kalyanshettar, S. Charki","doi":"10.22038/IJN.2021.52842.1948","DOIUrl":"https://doi.org/10.22038/IJN.2021.52842.1948","url":null,"abstract":"COVID-19 in neonates is an emerging challenge to pediatricians. Majority of the neonates with COVID-19 described so far are suspected to be due to postnatal transmission. Vertical transmission has been reported in 2 case cohort studies till date.32 weeks preemie born to primigravida mother with history of Preterm premature rupture of membranes (PPROM) was admitted in NICU with birth weight of 2 kg in view of respiratory distress. Neonate developed arterial thrombosis on first day of life and subsequent gangrene of right foot and tested positive for serology and rtPCR of SARS-CoV-2 with elevated inflammatory markers (CRP, D Dimer, Serum Ferritin, Lactate dehydrogenase). The mother was asymptomatic and hence was not tested for SARS-CoV-2 antenatally. After the confirmation in neonate, mother was also tested for SARS-CoV-2 and she tested positive by rtPCR as well as serology.This rare presentation calls for further research in transmission patterns either antenatally or vertical transmission. This report emphasizes the possibility of vertical transmission of COVID-19 in neonates from asymptomatic mother, with significant, early onset neonatal infection in the form of thrombosis.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77292506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-10DOI: 10.22038/IJN.2021.50687.1896
Solale Alidadian, N. Mahmoodi, M. Naderifar, A. Navidian, A. abasi
Background : The painful procedure of drawing blood from heel(HL) in the neonatal intensive care unit (NICU) is necessary for some diagnostic tests, but it can have negative effects on the physiological criteria of the preterm infants. The goal of this study is to compare the effect of lullaby and kangaroo care on the physiological criteria of preterm infants admitted to NICU during (HL).Materials and Methods: This clinical trial with a crossover design was conducted on 60 preterm infants (30-36 weeks of gestation) admitted to NICU at Ali Ibn Abitaleb Hospital in Zahedan in 2019. The infants were randomly divided equally into two groups of lullaby and kangaroo care (n=30 in each group). In the former group, lullaby was played for infants through headphones for 30 min, and in the latter group, the infant was placed in the mother's arms for the same time. Physiological criteria were recorded before (0 min), during (15 min) and after the procedure (30 min). Data were analyzed using SPSS 22 software and independent T-tests and Chi square test. Results: There was no statistically significant difference between the mean gestation age of neonates in the lullaby (32.63± 1.92) and kangaroo care (32.69± 1.92) group (p=1.000). The results of independent sample T-test showed that during the intervention, there was a difference between the mean pulse rate (P=0.015), respiration R (P=0.003) and arterial oxygen saturation percentage (P
背景:在新生儿重症监护病房(NICU)进行足跟抽血(HL)的痛苦过程是一些诊断检查所必需的，但它可能对早产儿的生理标准产生负面影响。本研究的目的是比较摇篮曲和袋鼠式护理对新生儿重症监护病房(NICU)早产儿生理标准的影响。材料与方法:本临床试验采用交叉设计，对2019年扎黑丹Ali Ibn Abitaleb医院NICU收治的60例早产儿(妊娠30-36周)进行研究。将婴儿随机分为两组，每组30例。前一组通过耳机为婴儿播放催眠曲30分钟，后一组将婴儿放在母亲怀里同样时间。记录手术前(0分钟)、手术中(15分钟)和手术后(30分钟)的生理指标。数据分析采用SPSS 22软件，采用独立t检验和卡方检验。结果:摇篮曲组新生儿平均胎龄(32.63±1.92)与袋鼠护理组(32.69±1.92)比较，差异无统计学意义(p=1.000)。独立样本t检验结果显示，干预期间，患者的平均脉搏率(P=0.015)、呼吸R (P=0.003)和动脉血氧饱和度(P=0.003)的差异均有统计学意义
{"title":"Comparison the Effect of Lullaby and Kangaroo Care on Physiological Criteria during Heel lance in Preterm infants at the Neonatal Intensive Care Unit","authors":"Solale Alidadian, N. Mahmoodi, M. Naderifar, A. Navidian, A. abasi","doi":"10.22038/IJN.2021.50687.1896","DOIUrl":"https://doi.org/10.22038/IJN.2021.50687.1896","url":null,"abstract":"Background : The painful procedure of drawing blood from heel(HL) in the neonatal intensive care unit (NICU) is necessary for some diagnostic tests, but it can have negative effects on the physiological criteria of the preterm infants. The goal of this study is to compare the effect of lullaby and kangaroo care on the physiological criteria of preterm infants admitted to NICU during (HL).Materials and Methods: This clinical trial with a crossover design was conducted on 60 preterm infants (30-36 weeks of gestation) admitted to NICU at Ali Ibn Abitaleb Hospital in Zahedan in 2019. The infants were randomly divided equally into two groups of lullaby and kangaroo care (n=30 in each group). In the former group, lullaby was played for infants through headphones for 30 min, and in the latter group, the infant was placed in the mother's arms for the same time. Physiological criteria were recorded before (0 min), during (15 min) and after the procedure (30 min). Data were analyzed using SPSS 22 software and independent T-tests and Chi square test. Results: There was no statistically significant difference between the mean gestation age of neonates in the lullaby (32.63± 1.92) and kangaroo care (32.69± 1.92) group (p=1.000). The results of independent sample T-test showed that during the intervention, there was a difference between the mean pulse rate (P=0.015), respiration R (P=0.003) and arterial oxygen saturation percentage (P","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88624996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-10DOI: 10.22038/IJN.2021.51070.1902
Birhanu Wubale Yirdaw
Background: Neonatal period, the first 28 days of life, represent the most vulnerable time for a child’s survival. Neonatal mortality is a concern for the global population, especially in developing countries. The majority of neonatal mortality occurs at home where only a few families recognize key danger signs of neonatal illness. In low and middle-income countries like Ethiopia, the ability of mothers to recognize the common danger signs of neonatal illness and seek appropriate care is instrumental in reducing neonatal deaths.Objective: Aimed to assess the knowledge on neonatal danger signs and associated factors among mothers who gave birth in the last one year before this study in Debre Markos, Northwestern Ethiopia.Methods: A community-based, cross-sectional study was conducted. A Cluster sampling technique was used to select the study participants. Data were entered into EpiInfo and exported to SPSS for analysis. Variables in binary logistic regression with a P-value
{"title":"KNOWLEDGE ON NEONATAL DANGER SIGNS AND ASSOCIATED FACTORS AMONG MOTHERS WHO GAVE BIRTH IN THE LAST ONE YEAR PRIOR TO THIS STUDY IN DEBRE MARKOS, NORTHWESTERN ETHIOPIA 2017.","authors":"Birhanu Wubale Yirdaw","doi":"10.22038/IJN.2021.51070.1902","DOIUrl":"https://doi.org/10.22038/IJN.2021.51070.1902","url":null,"abstract":"Background: Neonatal period, the first 28 days of life, represent the most vulnerable time for a child’s survival. Neonatal mortality is a concern for the global population, especially in developing countries. The majority of neonatal mortality occurs at home where only a few families recognize key danger signs of neonatal illness. In low and middle-income countries like Ethiopia, the ability of mothers to recognize the common danger signs of neonatal illness and seek appropriate care is instrumental in reducing neonatal deaths.Objective: Aimed to assess the knowledge on neonatal danger signs and associated factors among mothers who gave birth in the last one year before this study in Debre Markos, Northwestern Ethiopia.Methods: A community-based, cross-sectional study was conducted. A Cluster sampling technique was used to select the study participants. Data were entered into EpiInfo and exported to SPSS for analysis. Variables in binary logistic regression with a P-value","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73474553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-10DOI: 10.22038/IJN.2021.33734.1488
Wesam A. Mokhtar, N. Kamal, L. Sherief, Sherief Z. Kamel
Background & Objectives:Despite the great improvement in the outcome of sick neonates after the effective widespread introduction of mechanical ventilation in neonatal intensive care units, a significant proportion of high fatality is still detected among them. This study was conducted to identify the complications, outcome, and causes of death among a sample of critically ill Egyptian neonates mechanically ventilated using pressure-control-mode.Patients & Methods:Two-hundred-forty patients fulfilling the study inclusion criteria were prospectively enrolled in the current study. Those with multiple congenital malformations or post-surgical cases were excluded from the study. Data regarding history taking, clinical examination, indication for mechanical ventilation, complications related to mechanical ventilation and outcome were collected, recorded and analyzed. Results: The incidence of complications related to mechanical ventilation was 104 (43.3%) with reported increase in the incidence of VAP (20%). Also, the incidence of complications related to disease pattern was 136 (56.7%) with reported increase in the incidence of sepsis & septic shock (22.5%). It has been observed that 124 (51.7%) of the studied neonates had favorable outcome, however, the remaining 116 (48.3%) unfortunately expired with significant increase in the incidence of VAP among the expired group (P=0.013). Smaller gestational age and lower birth weight were the most significant risk factors. Conclusions:In Egypt; as an example of developing countries; mortality among critically ill mechanically ventilated pressure-control-mode neonates is significantly high approaching 48.3% with VAP being the most common cause of death.
{"title":"Mortality Risk in Mechanically Ventilated Neonates: A Developing Country Experience","authors":"Wesam A. Mokhtar, N. Kamal, L. Sherief, Sherief Z. Kamel","doi":"10.22038/IJN.2021.33734.1488","DOIUrl":"https://doi.org/10.22038/IJN.2021.33734.1488","url":null,"abstract":"Background & Objectives:Despite the great improvement in the outcome of sick neonates after the effective widespread introduction of mechanical ventilation in neonatal intensive care units, a significant proportion of high fatality is still detected among them. This study was conducted to identify the complications, outcome, and causes of death among a sample of critically ill Egyptian neonates mechanically ventilated using pressure-control-mode.Patients & Methods:Two-hundred-forty patients fulfilling the study inclusion criteria were prospectively enrolled in the current study. Those with multiple congenital malformations or post-surgical cases were excluded from the study. Data regarding history taking, clinical examination, indication for mechanical ventilation, complications related to mechanical ventilation and outcome were collected, recorded and analyzed. Results: The incidence of complications related to mechanical ventilation was 104 (43.3%) with reported increase in the incidence of VAP (20%). Also, the incidence of complications related to disease pattern was 136 (56.7%) with reported increase in the incidence of sepsis & septic shock (22.5%). It has been observed that 124 (51.7%) of the studied neonates had favorable outcome, however, the remaining 116 (48.3%) unfortunately expired with significant increase in the incidence of VAP among the expired group (P=0.013). Smaller gestational age and lower birth weight were the most significant risk factors. Conclusions:In Egypt; as an example of developing countries; mortality among critically ill mechanically ventilated pressure-control-mode neonates is significantly high approaching 48.3% with VAP being the most common cause of death.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91188094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-10DOI: 10.22038/IJN.2021.51421.1909
G. Bayani, S. Mafinejad, H. Ehteshammanesh, E. Sharifian, Mahboobeh Esmati, Mona Akbarian Sanavi, S. Mollazadeh
Objective: Given the contradictory results of studies on the efficacy of probiotics in reducing necrotizing enterocolitis and few studies in Iran, we decided to investigate the effect of probiotics on milk tolerance and prevention of necrotizing enterocolitis in preterm infants.Patients and Methods: This study was a randomized triple-blind clinical trial conducted on all preterm infants between 30 and 36 gestation weeks and body birth weight >1250 g hospitalized in neonatal intensive care unit at Bentolhoda hospital in Bojnurd. Then, 76 eligible neonates were randomly divided into two groups of receiving oral placebo (n=386) and BB care probiotic (n=3638). Information about early or late necrotizing enterocolitis (after 7 days of birth), types of necrotizing enterocolitis (grade I, II and III), length of hospital stayduration of hospitalization, time to reach complete oral nutrition, weight at discharge and milk tolerance based on hospital checklist were extracted.Results: In this study, 52.6% of infants in control group and 47.4% of newborns in the intervention group were male and no significant difference was seen between the two groups (p = 0.646). Incidence of necrotizing enterocolitis There was was significantly a reduced statistically significantamong intervention group difference between the two groups in the terms of incidence of necrotizing enterocolitis. The feeding onset of milk feeding in the placebo group was started significantly later than intervention group. There was alsoWe found a significant difference between the two groups in the length of hospital stay as well as weight gain during hospitalization.Conclusion: According to the results of this study, the useadministration of probiotics in preterm neonates might prevents necrotizingprevent necrotizing enterocolitis, as well as and shorten the time of feeding onset and duration of hospitalization.not only to reach full oral nutrition, but also length of hospitalization.
{"title":"The effect of probiotics on enteral milk tolerance and prevention of necrotizing enterocolitis in preterm infants","authors":"G. Bayani, S. Mafinejad, H. Ehteshammanesh, E. Sharifian, Mahboobeh Esmati, Mona Akbarian Sanavi, S. Mollazadeh","doi":"10.22038/IJN.2021.51421.1909","DOIUrl":"https://doi.org/10.22038/IJN.2021.51421.1909","url":null,"abstract":"Objective: Given the contradictory results of studies on the efficacy of probiotics in reducing necrotizing enterocolitis and few studies in Iran, we decided to investigate the effect of probiotics on milk tolerance and prevention of necrotizing enterocolitis in preterm infants.Patients and Methods: This study was a randomized triple-blind clinical trial conducted on all preterm infants between 30 and 36 gestation weeks and body birth weight >1250 g hospitalized in neonatal intensive care unit at Bentolhoda hospital in Bojnurd. Then, 76 eligible neonates were randomly divided into two groups of receiving oral placebo (n=386) and BB care probiotic (n=3638). Information about early or late necrotizing enterocolitis (after 7 days of birth), types of necrotizing enterocolitis (grade I, II and III), length of hospital stayduration of hospitalization, time to reach complete oral nutrition, weight at discharge and milk tolerance based on hospital checklist were extracted.Results: In this study, 52.6% of infants in control group and 47.4% of newborns in the intervention group were male and no significant difference was seen between the two groups (p = 0.646). Incidence of necrotizing enterocolitis There was was significantly a reduced statistically significantamong intervention group difference between the two groups in the terms of incidence of necrotizing enterocolitis. The feeding onset of milk feeding in the placebo group was started significantly later than intervention group. There was alsoWe found a significant difference between the two groups in the length of hospital stay as well as weight gain during hospitalization.Conclusion: According to the results of this study, the useadministration of probiotics in preterm neonates might prevents necrotizingprevent necrotizing enterocolitis, as well as and shorten the time of feeding onset and duration of hospitalization.not only to reach full oral nutrition, but also length of hospitalization.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74991869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.22038/IJN.2020.50902.1895
M. Khosravifar, H. Babaei, Nona Rahbari
Background: Pentalogy of Cantrell (PC) is an extremely rare congenital anomaly which was first described in 1985. The incidence of the PC has been reported to vary from 5.5-7.9 cases per million live births. This anomaly involves diaphragmatic pericardial defects, lower sternal defect, intracardiac anomalies, ventral abdominal wall abnormality, and anterior diaphragmatic defect. Considering the number of presented anomalies, PC is classified into three groups of certain, probable, or incomplete pentalogy. Although the etiology of PC is unknown, it has been assumed that abnormalities in intra embryonic mesodermal differentiation formation and migration at around 14-18 days after conception are responsible for the anomalies observed in PC. The prenatal diagnosis of the PC can be made via prenatal two-dimensional or three-dimensional ultrasound. Case report: This case report investigated an Iranian 2-hour-old full-term neonate who was referred to Imam Reza Hospital, Kermanshah, Iran, due to respiratory distress and abdominal wall defect. The patient was finally diagnosed with a probable PC, although his prenatal investigations were considered normal. Conclusion: Although ultrasonography is a widely available tool for prenatal diagnosis of PC, as in our case, the absence of ectopic heart and omphalocele makes the prenatal diagnosis of PC via ultrasonography less possible. Keyword
{"title":"Pentalogy of Cantrell: A case report of probable pentalogy of Cantrell in a full-term neonate","authors":"M. Khosravifar, H. Babaei, Nona Rahbari","doi":"10.22038/IJN.2020.50902.1895","DOIUrl":"https://doi.org/10.22038/IJN.2020.50902.1895","url":null,"abstract":"Background: Pentalogy of Cantrell (PC) is an extremely rare congenital anomaly which was first described in 1985. The incidence of the PC has been reported to vary from 5.5-7.9 cases per million live births. This anomaly involves diaphragmatic pericardial defects, lower sternal defect, intracardiac anomalies, ventral abdominal wall abnormality, and anterior diaphragmatic defect. Considering the number of presented anomalies, PC is classified into three groups of certain, probable, or incomplete pentalogy. Although the etiology of PC is unknown, it has been assumed that abnormalities in intra embryonic mesodermal differentiation formation and migration at around 14-18 days after conception are responsible for the anomalies observed in PC. The prenatal diagnosis of the PC can be made via prenatal two-dimensional or three-dimensional ultrasound. Case report: This case report investigated an Iranian 2-hour-old full-term neonate who was referred to Imam Reza Hospital, Kermanshah, Iran, due to respiratory distress and abdominal wall defect. The patient was finally diagnosed with a probable PC, although his prenatal investigations were considered normal. Conclusion: Although ultrasonography is a widely available tool for prenatal diagnosis of PC, as in our case, the absence of ectopic heart and omphalocele makes the prenatal diagnosis of PC via ultrasonography less possible. Keyword","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"20 1","pages":"96-99"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74939208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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