Pub Date : 2026-01-26DOI: 10.1001/jamapediatrics.2025.5788
Elizabeth Barnert,Paul H Wise
{"title":"Safeguarding the Health of Children in Carceral Custody.","authors":"Elizabeth Barnert,Paul H Wise","doi":"10.1001/jamapediatrics.2025.5788","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.5788","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"1 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-26DOI: 10.1001/jamapediatrics.2025.5724
Mickey A Emmanuel,Mikhail Goldenberg,Lindsay A Thompson
{"title":"What Parents Should Know About Fire Safety.","authors":"Mickey A Emmanuel,Mikhail Goldenberg,Lindsay A Thompson","doi":"10.1001/jamapediatrics.2025.5724","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.5724","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"179 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-26DOI: 10.1001/jamapediatrics.2025.5822
Youngjin Stephanie Hong, Jessica Pac, Lawrence M. Berger
Importance Universal pre-kindergarten (UPK) programs are expanding across the US. Given the detrimental consequences of child maltreatment on children’s health and well-being, it is important to assess whether high-quality, full-time UPK programs can function as a population-level child maltreatment prevention strategy. Objective To examine the association between provision of a full-time UPK program and child protective services (CPS) investigation rates by leveraging the implementation of New York City’s Pre-K for All program. Design, Setting, and Participants This cross-sectional study used county-year-child age–level data from the 2010 to 2019 National Child Abuse and Neglect Data System Child Files to compare CPS investigation rate trajectories for children aged 4 and 8 years before and after UPK implementation. The data were analyzed from January to May 2025. Exposure Implementation of the UPK program. Main Outcomes and Measures The primary outcome was the rate of CPS investigations per 1000 children overall and for child neglect and child physical abuse. The investigation rate trajectories were compared using difference-in-differences and event study methods. Results A total of 1 606 525 children (mean [SD] age, 5.9 [2.0] years; 820 519 males [51%]) were included in the study. Of these children, 555 003 (35%) identified as Hispanic, 382 662 (24%) as non-Hispanic Black, 444 285 as non-Hispanic White (28%), and 213 576 children (13%) identified as other non-Hispanic race or ethnicities. The difference-in-differences analysis estimated that UPK implementation was associated with 4.0 (95% CI, −6.77 to −1.11) fewer CPS investigations per 1000 children aged 4 years relative to investigations among children aged 8 years. This finding was attributable to reductions in the rate of child neglect investigations, with no statistically significant change in physical abuse investigations. The event study models illustrate that UPK implementation led to greater reductions in CPS investigations over time, reaching a reduction of 8.0 (95% CI, −11.72 to −5.10) fewer neglect investigations per 1000 children 2 years after implementation. Moreover, the subgroup analyses by race and ethnicity show that reductions in neglect investigations were disproportionately concentrated among racial and ethnic minority populations, particularly the non-Hispanic Black population, which had a reduction of 80 (95% CI, −176.47 to −17.02) neglect investigations per 1000 children 2 years after implementation. Conclusions and Relevance This study found that UPK may be associated with reduced CPS involvement, particularly for child neglect, and may help mitigate racial and ethnic disparities in CPS involvement. Reductions in child neglect associated with UPK could benefit children’s health and well-being in the short- and long-term; these findings offer insights for policymakers and advocates regarding broader benefits associated with UPK.
{"title":"Universal Pre-Kindergarten for Child Maltreatment Prevention","authors":"Youngjin Stephanie Hong, Jessica Pac, Lawrence M. Berger","doi":"10.1001/jamapediatrics.2025.5822","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.5822","url":null,"abstract":"Importance Universal pre-kindergarten (UPK) programs are expanding across the US. Given the detrimental consequences of child maltreatment on children’s health and well-being, it is important to assess whether high-quality, full-time UPK programs can function as a population-level child maltreatment prevention strategy. Objective To examine the association between provision of a full-time UPK program and child protective services (CPS) investigation rates by leveraging the implementation of New York City’s Pre-K for All program. Design, Setting, and Participants This cross-sectional study used county-year-child age–level data from the 2010 to 2019 National Child Abuse and Neglect Data System Child Files to compare CPS investigation rate trajectories for children aged 4 and 8 years before and after UPK implementation. The data were analyzed from January to May 2025. Exposure Implementation of the UPK program. Main Outcomes and Measures The primary outcome was the rate of CPS investigations per 1000 children overall and for child neglect and child physical abuse. The investigation rate trajectories were compared using difference-in-differences and event study methods. Results A total of 1 606 525 children (mean [SD] age, 5.9 [2.0] years; 820 519 males [51%]) were included in the study. Of these children, 555 003 (35%) identified as Hispanic, 382 662 (24%) as non-Hispanic Black, 444 285 as non-Hispanic White (28%), and 213 576 children (13%) identified as other non-Hispanic race or ethnicities. The difference-in-differences analysis estimated that UPK implementation was associated with 4.0 (95% CI, −6.77 to −1.11) fewer CPS investigations per 1000 children aged 4 years relative to investigations among children aged 8 years. This finding was attributable to reductions in the rate of child neglect investigations, with no statistically significant change in physical abuse investigations. The event study models illustrate that UPK implementation led to greater reductions in CPS investigations over time, reaching a reduction of 8.0 (95% CI, −11.72 to −5.10) fewer neglect investigations per 1000 children 2 years after implementation. Moreover, the subgroup analyses by race and ethnicity show that reductions in neglect investigations were disproportionately concentrated among racial and ethnic minority populations, particularly the non-Hispanic Black population, which had a reduction of 80 (95% CI, −176.47 to −17.02) neglect investigations per 1000 children 2 years after implementation. Conclusions and Relevance This study found that UPK may be associated with reduced CPS involvement, particularly for child neglect, and may help mitigate racial and ethnic disparities in CPS involvement. Reductions in child neglect associated with UPK could benefit children’s health and well-being in the short- and long-term; these findings offer insights for policymakers and advocates regarding broader benefits associated with UPK.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"64 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146048222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-26DOI: 10.1001/jamapediatrics.2025.5858
Nassr Nama,Stephanie Liebert,Mario Abaji,Amy DeLaroche,Kristy Carlin,Teresa Jewell,David D'Arienzo,Alastair Fung,David Gremse,Joshua L Bonkowsky,Maida Chen,Eyal Sagiv,Bruce Herman,Elise Lu,Peter J Gill,Joel S Tieder,Eric R Coon
ImportanceSince the introduction of the brief resolved unexplained event (BRUE) terminology, underpowered and conflicting research has led to persistent clinical uncertainty regarding the frequency of adverse outcomes, prognostic risk factors, and the diagnostic testing utility, contributing to wide practice variations.ObjectiveTo (1) establish the frequency of serious underlying diagnoses and 3-month mortality after a BRUE in infants; (2) identify prognostic risk factors; and (3) quantify the diagnostic yield of common investigations.Data SourcesPubMed, Embase, Cochrane, and gray literature sources from January 2016 through July 2025.Study SelectionCohort studies, case-control studies, and clinical trials of infants meeting 2016 American Academy of Pediatrics diagnostic criteria for BRUE.Data Extraction and SynthesisData were extracted by 1 reviewer and verified by a second. Random-effects meta-analyses were used to pool data. Grading of Recommendations Assessment, Development, and Evaluation was used to assess certainty in evidence.Main Outcomes and MeasuresThe primary outcomes were pooled prevalence of serious underlying diagnosis and 3-month cumulative mortality. Secondary outcomes included prognostic risk factors and diagnostic yield of specific tests.ResultsFrom 664 citations, 24 studies (6603 infants) were included. The pooled prevalence of a serious underlying diagnosis was 6.0% (95% CI, 4.6%-7.9%; high certainty), and cumulative 3-month mortality was 1 death per 1851 infants (95% CI, 1 death per 597-5739 infants; moderate certainty). A history of multiple events (risk difference [RD], 3.7%; 95% CI, 1.7%-6.2%; high certainty) and prematurity (RD, 2.6%; 95% CI, 0.6%-5.2%; high certainty) were associated with increased risk of serious underlying diagnosis, while being aged 60 days or younger was not (RD, -0.5%; 95% CI, -2.7% to 3.0%; high certainty). Routine investigations were exceedingly low yield: metabolic panels had 0% yield (95% CI, 0%-0.5%; number needed to test [NNT] = 852; moderate certainty), electrocardiograms, 0.2% yield (95% CI, 0.0%-0.9%; NNT = 623; high certainty); and chest radiographs, 0.4% yield (95% CI, 0.2%-1.0%; NNT = 256; high certainty).Conclusions and RelevanceThis systematic review and meta-analysis found that infant mortality after a BRUE was exceedingly rare, and a serious underlying diagnosis was present in a small but important group of infants; most routine diagnostic tests added little value and not infrequently had false-positive results. Clinical focus should therefore shift from blanket investigations to a targeted, risk-informed approach grounded in a few reliable higher-risk features. These findings provide a robust evidence basis for guideline revision.
{"title":"Infant Outcomes, Risk Factors, and Diagnostic Yield After a Brief Resolved Unexplained Event: A Systematic Review and Meta-Analysis.","authors":"Nassr Nama,Stephanie Liebert,Mario Abaji,Amy DeLaroche,Kristy Carlin,Teresa Jewell,David D'Arienzo,Alastair Fung,David Gremse,Joshua L Bonkowsky,Maida Chen,Eyal Sagiv,Bruce Herman,Elise Lu,Peter J Gill,Joel S Tieder,Eric R Coon","doi":"10.1001/jamapediatrics.2025.5858","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.5858","url":null,"abstract":"ImportanceSince the introduction of the brief resolved unexplained event (BRUE) terminology, underpowered and conflicting research has led to persistent clinical uncertainty regarding the frequency of adverse outcomes, prognostic risk factors, and the diagnostic testing utility, contributing to wide practice variations.ObjectiveTo (1) establish the frequency of serious underlying diagnoses and 3-month mortality after a BRUE in infants; (2) identify prognostic risk factors; and (3) quantify the diagnostic yield of common investigations.Data SourcesPubMed, Embase, Cochrane, and gray literature sources from January 2016 through July 2025.Study SelectionCohort studies, case-control studies, and clinical trials of infants meeting 2016 American Academy of Pediatrics diagnostic criteria for BRUE.Data Extraction and SynthesisData were extracted by 1 reviewer and verified by a second. Random-effects meta-analyses were used to pool data. Grading of Recommendations Assessment, Development, and Evaluation was used to assess certainty in evidence.Main Outcomes and MeasuresThe primary outcomes were pooled prevalence of serious underlying diagnosis and 3-month cumulative mortality. Secondary outcomes included prognostic risk factors and diagnostic yield of specific tests.ResultsFrom 664 citations, 24 studies (6603 infants) were included. The pooled prevalence of a serious underlying diagnosis was 6.0% (95% CI, 4.6%-7.9%; high certainty), and cumulative 3-month mortality was 1 death per 1851 infants (95% CI, 1 death per 597-5739 infants; moderate certainty). A history of multiple events (risk difference [RD], 3.7%; 95% CI, 1.7%-6.2%; high certainty) and prematurity (RD, 2.6%; 95% CI, 0.6%-5.2%; high certainty) were associated with increased risk of serious underlying diagnosis, while being aged 60 days or younger was not (RD, -0.5%; 95% CI, -2.7% to 3.0%; high certainty). Routine investigations were exceedingly low yield: metabolic panels had 0% yield (95% CI, 0%-0.5%; number needed to test [NNT] = 852; moderate certainty), electrocardiograms, 0.2% yield (95% CI, 0.0%-0.9%; NNT = 623; high certainty); and chest radiographs, 0.4% yield (95% CI, 0.2%-1.0%; NNT = 256; high certainty).Conclusions and RelevanceThis systematic review and meta-analysis found that infant mortality after a BRUE was exceedingly rare, and a serious underlying diagnosis was present in a small but important group of infants; most routine diagnostic tests added little value and not infrequently had false-positive results. Clinical focus should therefore shift from blanket investigations to a targeted, risk-informed approach grounded in a few reliable higher-risk features. These findings provide a robust evidence basis for guideline revision.","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"88 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-20DOI: 10.1001/jamapediatrics.2025.5636
Joseph W Kaempf,Ryan M McAdams,Michael Kuzniewicz
{"title":"Further Considerations on Late Preterm Antenatal Corticosteroid Use.","authors":"Joseph W Kaempf,Ryan M McAdams,Michael Kuzniewicz","doi":"10.1001/jamapediatrics.2025.5636","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.5636","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"30 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-20DOI: 10.1001/jamapediatrics.2025.5739
Ryan M McAdams,Wissam Shalish
{"title":"Speed and Safety in Pediatric Artificial Intelligence-Child in the Loop.","authors":"Ryan M McAdams,Wissam Shalish","doi":"10.1001/jamapediatrics.2025.5739","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.5739","url":null,"abstract":"","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"3 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-20DOI: 10.1001/jamapediatrics.2025.5866
Mariana Lenz Tarouco,Renato S Procianoy,T Michael O'Shea,Rita C Silveira
ImportanceChildren born very preterm or with very low birth weight are at higher risk for executive function deficits, affecting attention, self-regulation, and problem-solving. Early developmental interventions have shown potential benefits, but their long-term effect on executive functioning remains uncertain.ObjectiveTo evaluate whether an enhanced developmental intervention (EDI) initiated in the neonatal intensive care unit (NICU) and continued at home through the first 2 years improves executive function at school age in very preterm children.Design, Setting, and ParticipantsThis secondary analysis assessed school-aged outcomes from a randomized clinical trial of infants born with fewer than 32 weeks of gestation or with birth weight less than 1500 g from January 2016 to February 2019. Follow-up assessments were conducted from July 7, 2023, to August 16, 2024, at a single center in Porto Alegre, Brazil. Data analyses were completed from August to December 2024.InterventionEDI compared with usual care.Main Outcomes and MeasuresThe primary outcomes were the scaled scores of Developmental Neuropsychological Assessment, Second Edition, subtests, which measures auditory attention, inhibition, design fluency, and motor persistence. The examiner was masked to group allocation. Medical records identified children with neurodevelopmental conditions that precluded formal assessment. The effect size for the Mann-Whitney U test comparisons was calculated using the rank-biserial correlation. Binary logistic regression was used to compare performance in the primary outcomes. Sensitivity analyses were used for those lost to follow-up.ResultsOf the original randomized clinical trial, 80 children (96% of those eligible) were assessed at a mean (SD) age of 7 (1) years; 34 children (43%) were female. Baseline characteristics were similar between groups. In the primary analysis of median scaled scores, children who received EDI demonstrated significantly better performance across all 4 executive function domains compared to usual care (median scores, 12-14 vs 2-9; r = 0.44-0.77; all P < .001). All results remained significant after Bonferroni correction (P < .0125), indicating medium to large effect sizes. In the secondary analysis of performance classification, EDI was associated with higher odds of expected performance in design fluency (odds ratio, 11.3; 95% CI, 4.08-31.7; P < .001). No statistically significant differences were observed for the remaining 3 domains.Conclusions and RelevanceIn this secondary analysis of a randomized clinical trial, early EDI, beginning in the NICU and extending through the first 2 years, contributed to sustained improvements in executive function in very preterm children. These findings support the long-term neurodevelopmental benefits of early intervention, with potential implications for academic and socioemotional outcomes in children from low- and middle-income settings.Trial RegistrationClinicalTrials.gov Identifier: NC
早产儿或出生体重过低的儿童有较高的执行功能缺陷风险，影响注意力、自我调节和解决问题。早期发育干预已显示出潜在的益处，但其对执行功能的长期影响仍不确定。目的评价在新生儿重症监护病房（NICU）开始并在家中持续2年的强化发育干预（EDI）是否能改善极早产儿学龄期的执行功能。设计、环境和参与者这项二级分析评估了2016年1月至2019年2月期间出生的小于32周妊娠或出生体重小于1500克的婴儿的随机临床试验的学龄结果。随访评估于2023年7月7日至2024年8月16日在巴西阿雷格里港的一个中心进行。数据分析于2024年8月至12月完成。干预与常规护理比较。主要结果和测量主要结果是发育神经心理学评估第二版子测试的量表得分，该子测试测量听觉注意、抑制、设计流畅性和运动持久性。考官被蒙面到小组分配。医疗记录表明，儿童患有神经发育疾病，无法进行正式评估。Mann-Whitney U检验比较的效应量采用秩-双列相关法计算。采用二元逻辑回归比较主要结局的表现。对未随访的患者进行敏感性分析。在最初的随机临床试验中，80名儿童（96%符合条件的儿童）在平均（SD）年龄为7(1)岁时进行了评估；34例（43%）为女性。各组间基线特征相似。在中位评分的初步分析中，与常规护理相比，接受EDI治疗的儿童在所有4个执行功能领域的表现明显更好（中位评分，12-14 vs 2-9; r = 0.44-0.77；均P < 0.001）。经Bonferroni校正后，所有结果仍然显著(P <。0125)，表明中等到较大的效应大小。在性能分类的二次分析中，EDI与设计流畅性预期性能的较高几率相关（优势比，11.3;95% CI, 4.08-31.7; P < 0.001）。其余3个域差异无统计学意义。结论和相关性在一项随机临床试验的二级分析中，早期的EDI，从新生儿重症监护室开始，一直持续到前2年，有助于非常早产儿执行功能的持续改善。这些发现支持早期干预对神经发育的长期益处，并对中低收入儿童的学业和社会情感结果具有潜在影响。临床试验注册号：NCT02835612。
{"title":"Parent-Led Early Intervention in Very Preterm Infants and Executive Function at School Age: Secondary Analysis of a Randomized Clinical Trial.","authors":"Mariana Lenz Tarouco,Renato S Procianoy,T Michael O'Shea,Rita C Silveira","doi":"10.1001/jamapediatrics.2025.5866","DOIUrl":"https://doi.org/10.1001/jamapediatrics.2025.5866","url":null,"abstract":"ImportanceChildren born very preterm or with very low birth weight are at higher risk for executive function deficits, affecting attention, self-regulation, and problem-solving. Early developmental interventions have shown potential benefits, but their long-term effect on executive functioning remains uncertain.ObjectiveTo evaluate whether an enhanced developmental intervention (EDI) initiated in the neonatal intensive care unit (NICU) and continued at home through the first 2 years improves executive function at school age in very preterm children.Design, Setting, and ParticipantsThis secondary analysis assessed school-aged outcomes from a randomized clinical trial of infants born with fewer than 32 weeks of gestation or with birth weight less than 1500 g from January 2016 to February 2019. Follow-up assessments were conducted from July 7, 2023, to August 16, 2024, at a single center in Porto Alegre, Brazil. Data analyses were completed from August to December 2024.InterventionEDI compared with usual care.Main Outcomes and MeasuresThe primary outcomes were the scaled scores of Developmental Neuropsychological Assessment, Second Edition, subtests, which measures auditory attention, inhibition, design fluency, and motor persistence. The examiner was masked to group allocation. Medical records identified children with neurodevelopmental conditions that precluded formal assessment. The effect size for the Mann-Whitney U test comparisons was calculated using the rank-biserial correlation. Binary logistic regression was used to compare performance in the primary outcomes. Sensitivity analyses were used for those lost to follow-up.ResultsOf the original randomized clinical trial, 80 children (96% of those eligible) were assessed at a mean (SD) age of 7 (1) years; 34 children (43%) were female. Baseline characteristics were similar between groups. In the primary analysis of median scaled scores, children who received EDI demonstrated significantly better performance across all 4 executive function domains compared to usual care (median scores, 12-14 vs 2-9; r = 0.44-0.77; all P < .001). All results remained significant after Bonferroni correction (P < .0125), indicating medium to large effect sizes. In the secondary analysis of performance classification, EDI was associated with higher odds of expected performance in design fluency (odds ratio, 11.3; 95% CI, 4.08-31.7; P < .001). No statistically significant differences were observed for the remaining 3 domains.Conclusions and RelevanceIn this secondary analysis of a randomized clinical trial, early EDI, beginning in the NICU and extending through the first 2 years, contributed to sustained improvements in executive function in very preterm children. These findings support the long-term neurodevelopmental benefits of early intervention, with potential implications for academic and socioemotional outcomes in children from low- and middle-income settings.Trial RegistrationClinicalTrials.gov Identifier: NC","PeriodicalId":14683,"journal":{"name":"JAMA Pediatrics","volume":"100 1","pages":""},"PeriodicalIF":26.1,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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