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A Refined Mobile Health Intervention (SMARTFAMILY2.0) to Promote Physical Activity and Healthy Eating in a Family Setting: Randomized Controlled Trial. 在家庭环境中促进身体活动和健康饮食的精细移动健康干预(SMARTFAMILY2.0):随机对照试验
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-15 DOI: 10.2196/65558
Janis Fiedler, Kathrin Wunsch, Sebastian Hubenschmid, Harald Reiterer, Britta Renner, Alexander Woll
<p><strong>Background: </strong>Many mobile health (mHealth) apps focus on promoting physical activity (PA) and healthy eating (HE). However, there is limited empirical evidence regarding their effectiveness in initiating and sustaining behavior change, particularly among children and adolescents. Considering that behavior is influenced by social contexts, it is essential to take core settings like family dynamics into account when designing mHealth apps.</p><p><strong>Objective: </strong>The purpose of this study was to further develop and refine the SMARTFAMILY (SF) app targeting PA and HE in a collective family-based setting by enhancing design and usability, as well as by adding gamification aspects, health literacy, and just-in-time adaptive interventions to the first version of the app.</p><p><strong>Methods: </strong>The SF2.0 app, based on behavior change theories and techniques, was developed, implemented, and evaluated. The app was used in a collective family setting, with family members using it individually and cooperatively. In a cluster-randomized controlled trial, the intervention group (IG) used the app for 3 consecutive weeks, while the control group (CG) received no treatment. Primary outcomes included PA measured through self-reports and accelerometry, as well as self-reported fruit and vegetable intake (FVI) for HE. Secondary outcomes included intrinsic motivation, behavior-specific self-efficacy, and the Family Health Climate. A follow-up assessment (T<sub>2</sub>) was conducted 4 weeks after the postmeasurement (T<sub>1</sub>) to assess intervention effects. Multilevel analyses were performed in R (R Foundation for Statistical Computing), considering the hierarchical structure of individuals (level 1) within families (level 2).</p><p><strong>Results: </strong>Overall, 55 families (28 CG, 105/209; 27 IG, 104/209 participants) were recruited for the study. In total, 3 families (3 CG, n=12) chose to drop out of the study due to personal reasons before T<sub>0</sub>. Overall, no evidence for meaningful and statistically significant increases in PA was observed in favor of the IG of our physically active sample. However, the app elucidated positive effects in favor of the IG for FVI diary (T<sub>0</sub>-T<sub>1</sub>; P=.03), joint PA (T<sub>0</sub>-T<sub>1</sub>; P=.02 and T<sub>0</sub>-T<sub>2</sub>; P<.001), and joint family meals (T<sub>0</sub>-T<sub>1</sub>; P=.004).</p><p><strong>Conclusions: </strong>The SF2.0 trial evaluated an mHealth intervention designed to promote PA and HE within families. Despite incorporating a theoretical foundation, several behavior change techniques based on family life, and gamification and just-in-time adaptive intervention features, the intervention did not significantly increase PA levels among physically active participants. FVI, joint PA, and joint meals were improved within the IG. Previous studies on digital health interventions have produced mixed results, and family-based mHealth inter
背景:许多移动健康(mHealth)应用程序专注于促进身体活动(PA)和健康饮食(HE)。然而,关于它们在启动和维持行为改变方面的有效性,特别是在儿童和青少年中,经验证据有限。考虑到行为受到社会环境的影响,在设计移动健康应用程序时,必须考虑到家庭动态等核心环境。目的:本研究的目的是进一步开发和完善SMARTFAMILY (SF)应用程序,通过增强设计和可用性,以及在第一版应用程序中添加游戏化方面,健康素养和及时适应性干预措施,以集体家庭为基础的环境中针对PA和HE。方法:基于行为改变理论和技术的SF2.0应用程序开发,实施和评估。该应用程序是在一个集体家庭环境中使用的,家庭成员单独或合作地使用它。在一项集群随机对照试验中,干预组(IG)连续3周使用该应用程序,而对照组(CG)不接受任何治疗。主要结果包括通过自我报告和加速度计测量的PA,以及自我报告的HE水果和蔬菜摄入量(FVI)。次要结果包括内在动机、特定行为的自我效能感和家庭健康氛围。在测量后4周(T1)进行随访评估(T2)以评估干预效果。在R (R Foundation for Statistical Computing)中进行了多水平分析,考虑了家庭(水平2)中个体(水平1)的层次结构。结果:总共有55个家庭(28个CG, 105/209; 27个IG, 104/209)被纳入研究。在T0之前,共有3个家庭(3个CG, n=12)因个人原因选择退出研究。总的来说,没有观察到有意义的和统计学上显著的PA增加的证据,有利于我们的体力活动样本的IG。然而,该应用程序阐明了IG对FVI日记(T0-T1; P= 0.03),关节PA (T0-T1; P= 0.02和T0-T2; P0-T1; P= 0.004)的积极作用。结论:SF2.0试验评估了旨在促进家庭PA和HE的移动健康干预。尽管结合了理论基础,基于家庭生活的几种行为改变技术,以及游戏化和及时适应性干预的特征,干预并没有显著增加体力活动参与者的PA水平。IG内FVI、关节PA、关节膳食均有改善。以前关于数字健康干预的研究产生了不同的结果,基于家庭的移动健康干预仍然很少,对整个家庭行为和随机对照试验的关注有限。为了提高干预效果,未来的应用开发可以考虑加入更高级的功能,并应该关注不活跃的参与者。需要进一步的研究来更好地了解干预参与和为初级预防工作量身定制移动健康方法。试验注册:德国临床试验注册中心DRKS00010415;https://www.drks.de/search/en/trial/DRKS00010415.International注册报告标识符(irrid): RR2-10.2196/20534。
{"title":"A Refined Mobile Health Intervention (SMARTFAMILY2.0) to Promote Physical Activity and Healthy Eating in a Family Setting: Randomized Controlled Trial.","authors":"Janis Fiedler, Kathrin Wunsch, Sebastian Hubenschmid, Harald Reiterer, Britta Renner, Alexander Woll","doi":"10.2196/65558","DOIUrl":"10.2196/65558","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Many mobile health (mHealth) apps focus on promoting physical activity (PA) and healthy eating (HE). However, there is limited empirical evidence regarding their effectiveness in initiating and sustaining behavior change, particularly among children and adolescents. Considering that behavior is influenced by social contexts, it is essential to take core settings like family dynamics into account when designing mHealth apps.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The purpose of this study was to further develop and refine the SMARTFAMILY (SF) app targeting PA and HE in a collective family-based setting by enhancing design and usability, as well as by adding gamification aspects, health literacy, and just-in-time adaptive interventions to the first version of the app.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The SF2.0 app, based on behavior change theories and techniques, was developed, implemented, and evaluated. The app was used in a collective family setting, with family members using it individually and cooperatively. In a cluster-randomized controlled trial, the intervention group (IG) used the app for 3 consecutive weeks, while the control group (CG) received no treatment. Primary outcomes included PA measured through self-reports and accelerometry, as well as self-reported fruit and vegetable intake (FVI) for HE. Secondary outcomes included intrinsic motivation, behavior-specific self-efficacy, and the Family Health Climate. A follow-up assessment (T&lt;sub&gt;2&lt;/sub&gt;) was conducted 4 weeks after the postmeasurement (T&lt;sub&gt;1&lt;/sub&gt;) to assess intervention effects. Multilevel analyses were performed in R (R Foundation for Statistical Computing), considering the hierarchical structure of individuals (level 1) within families (level 2).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Overall, 55 families (28 CG, 105/209; 27 IG, 104/209 participants) were recruited for the study. In total, 3 families (3 CG, n=12) chose to drop out of the study due to personal reasons before T&lt;sub&gt;0&lt;/sub&gt;. Overall, no evidence for meaningful and statistically significant increases in PA was observed in favor of the IG of our physically active sample. However, the app elucidated positive effects in favor of the IG for FVI diary (T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;1&lt;/sub&gt;; P=.03), joint PA (T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;1&lt;/sub&gt;; P=.02 and T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;2&lt;/sub&gt;; P&lt;.001), and joint family meals (T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;1&lt;/sub&gt;; P=.004).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The SF2.0 trial evaluated an mHealth intervention designed to promote PA and HE within families. Despite incorporating a theoretical foundation, several behavior change techniques based on family life, and gamification and just-in-time adaptive intervention features, the intervention did not significantly increase PA levels among physically active participants. FVI, joint PA, and joint meals were improved within the IG. Previous studies on digital health interventions have produced mixed results, and family-based mHealth inter","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e65558"},"PeriodicalIF":6.2,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12750077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Quality and Features of Visual Acuity Apps Using the Mobile App Rating Scale: Systematic Review. 使用移动应用程序评分量表评估视觉敏锐度应用程序的质量和特征:系统回顾。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-12 DOI: 10.2196/65997
P Connor Lentz, Emily Dorairaj, Pranav Vasu, Isabella Wagner, Jaxson Jeffery, Farha Deceus, Nithya Boopathiraj, Yazan Abubaker, Darby D Miller, Antonio Jorge Forte, Syril Dorairaj

Background: Mobile visual acuity (VA) apps have emerged as valuable tools in both clinical and home settings, particularly in the context of expanding teleophthalmology. Despite the growing number of apps available to measure visual acuity, studies evaluating their overall quality, functionality, and clinical relevance are limited.

Objective: This study aimed to systematically evaluate the quality and features of mobile VA apps available on iOS and Android platforms using the clinically validated Mobile App Rating Scale (MARS).

Methods: A comprehensive search of the Google Play Store and Apple App Store was conducted between January 2024 and March 2024 using standardized search terms. Eligible apps included free, English-language VA testing tools not requiring external devices. App characteristics and features were extracted. Each app was independently evaluated by 2 trained reviewers using MARS, which rates engagement, functionality, aesthetics, information quality, and subjective quality on a 5-point scale.

Results: Of the 725 apps initially identified, 44 met the inclusion criteria, with 23 from the Google Play Store and 21 from the Apple App Store. The most common VA test optotypes used were Tumbling E (n=21; 48%), Snellen Chart (18/44; 41%), and Landolt C (n=14; 32%). Common supplemental features included color vision testing (n=20; 46%), astigmatism tests (n=13; 30%), Amsler grid (n=13; 30%), and contrast testing (n=12; 28%). The average MARS scores were comparable across platforms: 3.04 (SD 0.80) for Android and 3.02 (SD 0.84) for iOS. Functionality received the highest ratings (mean 3.65, SD 0.75 for Android; mean 3.71, SD 0.82 for iOS), while subjective quality received the lowest (mean 2.09, SD 1.01 for Android; mean 2.21, SD 1.01 for iOS). Few apps had undergone clinical validation. Only Apple App Store apps demonstrated significant correlations between MARS scores and app store star ratings.

Conclusions: VA apps exhibited considerable heterogeneity in quality, functionality, and clinical use. Total mean MARS scores were similar between the Google Play Store and the Apple App Store, suggesting that neither platform consistently offers superior app quality. While many apps are technically sound, low subjective-quality scores and a lack of clinical validation limit their current use in professional practice. These findings underscore the need for more rigorous app development and validation standards to improve their relevance and reliability in teleophthalmology.

背景:移动视力(VA)应用程序已经成为临床和家庭环境中有价值的工具,特别是在远程眼科不断扩大的背景下。尽管越来越多的应用程序可用于测量视力,但评估其整体质量,功能和临床相关性的研究是有限的。目的:本研究旨在使用临床验证的移动应用评定量表(MARS)系统评估iOS和Android平台上可用的移动VA应用的质量和功能。方法:在2024年1月至2024年3月期间,使用标准化搜索词对谷歌Play Store和Apple App Store进行综合搜索。合格的应用程序包括免费的英语VA测试工具,不需要外部设备。提取App特征和特征。每个应用程序都由2名训练有素的评论者使用MARS进行独立评估,MARS将用户粘性、功能、美学、信息质量和主观质量分为5个等级。结果:在最初确定的725款应用中,有44款符合纳入标准,其中23款来自bb0 Play Store, 21款来自Apple App Store。最常用的VA测试视型是翻滚E (n=21; 48%)、Snellen Chart(18/44; 41%)和Landolt C (n=14; 32%)。常见的补充功能包括色视觉测试(n=20; 46%)、散光测试(n=13; 30%)、Amsler网格测试(n=13; 30%)和对比度测试(n=12; 28%)。不同平台的平均MARS分数具有可比性:Android为3.04 (SD 0.80), iOS为3.02 (SD 0.84)。功能评分最高(Android平均3.65,SD 0.75; iOS平均3.71,SD 0.82),主观质量评分最低(Android平均2.09,SD 1.01; iOS平均2.21,SD 1.01)。很少有应用程序经过临床验证。只有苹果App Store应用显示出MARS分数与应用商店星级评级之间的显著相关性。结论:VA应用程序在质量、功能和临床使用方面表现出相当大的异质性。bb0 Play Store和苹果App Store的总平均MARS分数相似,这表明这两个平台的应用质量都不高。虽然许多应用程序在技术上是合理的,但主观质量得分低,缺乏临床验证,限制了它们目前在专业实践中的使用。这些发现强调需要更严格的应用程序开发和验证标准,以提高其在远程眼科中的相关性和可靠性。
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引用次数: 0
Multimodal Sleep Measurement and Alignment Analysis in Outpatients With Major Depressive Episode: Observational Study. 重性抑郁发作门诊患者的多模态睡眠测量与校准分析:观察性研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-11 DOI: 10.2196/82465
Afrooz Mahir, Nguyen Luong, Ilya Baryshnikov, Annasofia Martikkala, Erkki Isometsä, Talayeh Aledavood
<p><strong>Background: </strong>Sleep is essential for overall health and plays a critical role in the diagnosis of psychiatric disorders. Although polysomnography remains the gold standard for measuring sleep, its reliance on laboratory settings limits its feasibility for long-term, naturalistic monitoring, particularly for patients with mental disorders.</p><p><strong>Objective: </strong>This study assesses sleep-tracking reliability and alignment in healthy individuals and patients with mood disorders using wearables, nearables, and ecological momentary assessment, while examining measurement biases and the impact of seasonal and demographic factors on discrepancies across methods.</p><p><strong>Methods: </strong>We conducted a 14-day study in Finland and enrolled a total of 201 participants, comprising patients with a major depressive episode and healthy controls. Of these, 169 participants with sufficient observations were retained for further analyses. Participants' sleep patterns (onset, offset, and total sleep time [TST]) were gathered daily from an actigraph (Actiwatch 2), a bed sensor (Murata SCA11H), mobile screen events, and a daily survey. The alignment between sleep measurement methods was evaluated using Bland-Altman plots and Pearson correlation. Linear mixed models were used to assess the effects of demographics, season, and disorder type on the sleep measures alignment.</p><p><strong>Results: </strong>Patients exhibited greater variability in sleep measures than healthy controls. For sleep onset, mean biases between devices were small and not statistically significant in either group, with moderate to strong correlations. In contrast, sleep offset showed significantly larger biases in patients: actigraph versus bed (+34.9 minutes; P=.01), smartphone versus bed (-45.3 minutes; P=.004), and actigraph versus smartphone (+78.7 minutes; P<.001), while controls exhibited minimal and nonsignificant differences. For TST, smartphone underestimates sleep compared to both bed sensors (-0.71 minutes; P<.001) and actigraphs (-1.35 minutes; P<.001). Across devices, TST correlations remained low, spanning r=0.12 (P=.58) to r=0.55 (P=.10) in controls and r=0.17 (P=.19) to r=0.43 (P=.002) in patients. Mixed models showed that older age was linked to better sleep offset alignment between actigraphy and bed sensors (β=-0.02, 95% CI -0.04 to 0.00; P=.048), as well as smartphone and bed sensor (β=-0.03, 95% CI -0.06 to 0.00; P=.03). Patients with bipolar/borderline personality disorder showed lower TST alignment, and alignment between smartphone and bed sensor was worse in females (β=-1.03, 95% CI -1.74 to -0.33, P=.004). Longer daylight duration was also associated with improved alignment in sleep offset and TST.</p><p><strong>Conclusions: </strong>This study demonstrates the feasibility of using actigraphy, smartphone data, and bed sensors for sleep tracking in naturalistic settings with patients. It highlights measurement biases across devices, t
背景:睡眠对整体健康至关重要,在精神疾病的诊断中起着关键作用。尽管多导睡眠图仍然是测量睡眠的黄金标准,但它对实验室环境的依赖限制了其长期、自然监测的可行性,特别是对精神障碍患者。目的:本研究使用可穿戴设备、可穿戴设备和生态瞬时评估来评估健康个体和情绪障碍患者的睡眠跟踪可靠性和一致性,同时检查测量偏差以及季节和人口因素对不同方法差异的影响。方法:我们在芬兰进行了一项为期14天的研究,共招募了201名参与者,包括重度抑郁症发作患者和健康对照。其中,有充分观察结果的169名参与者被保留以作进一步分析。每天通过活动记录仪(Actiwatch 2)、床上传感器(Murata SCA11H)、手机屏幕事件和每日调查收集参与者的睡眠模式(开始、偏移和总睡眠时间[TST])。使用Bland-Altman图和Pearson相关性评估睡眠测量方法之间的一致性。使用线性混合模型来评估人口统计学、季节和疾病类型对睡眠测量一致性的影响。结果:与健康对照组相比,患者在睡眠测量方面表现出更大的变异性。对于睡眠开始,两组设备之间的平均偏差很小,没有统计学意义,具有中等到强的相关性。相比之下,睡眠偏移在患者中显示出更大的偏差:活动记录仪对床(+34.9分钟,P= 0.01),智能手机对床(-45.3分钟,P= 0.004),活动记录仪对智能手机(+78.7分钟)。结论:本研究证明了在自然环境下使用活动记录仪、智能手机数据和床传感器进行睡眠跟踪的可行性。它强调了不同设备的测量偏差,季节性变化对芬兰等独特地理区域睡眠研究的影响,以及影响睡眠测量差异的关键人口因素。
{"title":"Multimodal Sleep Measurement and Alignment Analysis in Outpatients With Major Depressive Episode: Observational Study.","authors":"Afrooz Mahir, Nguyen Luong, Ilya Baryshnikov, Annasofia Martikkala, Erkki Isometsä, Talayeh Aledavood","doi":"10.2196/82465","DOIUrl":"10.2196/82465","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Sleep is essential for overall health and plays a critical role in the diagnosis of psychiatric disorders. Although polysomnography remains the gold standard for measuring sleep, its reliance on laboratory settings limits its feasibility for long-term, naturalistic monitoring, particularly for patients with mental disorders.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study assesses sleep-tracking reliability and alignment in healthy individuals and patients with mood disorders using wearables, nearables, and ecological momentary assessment, while examining measurement biases and the impact of seasonal and demographic factors on discrepancies across methods.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We conducted a 14-day study in Finland and enrolled a total of 201 participants, comprising patients with a major depressive episode and healthy controls. Of these, 169 participants with sufficient observations were retained for further analyses. Participants' sleep patterns (onset, offset, and total sleep time [TST]) were gathered daily from an actigraph (Actiwatch 2), a bed sensor (Murata SCA11H), mobile screen events, and a daily survey. The alignment between sleep measurement methods was evaluated using Bland-Altman plots and Pearson correlation. Linear mixed models were used to assess the effects of demographics, season, and disorder type on the sleep measures alignment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Patients exhibited greater variability in sleep measures than healthy controls. For sleep onset, mean biases between devices were small and not statistically significant in either group, with moderate to strong correlations. In contrast, sleep offset showed significantly larger biases in patients: actigraph versus bed (+34.9 minutes; P=.01), smartphone versus bed (-45.3 minutes; P=.004), and actigraph versus smartphone (+78.7 minutes; P&lt;.001), while controls exhibited minimal and nonsignificant differences. For TST, smartphone underestimates sleep compared to both bed sensors (-0.71 minutes; P&lt;.001) and actigraphs (-1.35 minutes; P&lt;.001). Across devices, TST correlations remained low, spanning r=0.12 (P=.58) to r=0.55 (P=.10) in controls and r=0.17 (P=.19) to r=0.43 (P=.002) in patients. Mixed models showed that older age was linked to better sleep offset alignment between actigraphy and bed sensors (β=-0.02, 95% CI -0.04 to 0.00; P=.048), as well as smartphone and bed sensor (β=-0.03, 95% CI -0.06 to 0.00; P=.03). Patients with bipolar/borderline personality disorder showed lower TST alignment, and alignment between smartphone and bed sensor was worse in females (β=-1.03, 95% CI -1.74 to -0.33, P=.004). Longer daylight duration was also associated with improved alignment in sleep offset and TST.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This study demonstrates the feasibility of using actigraphy, smartphone data, and bed sensors for sleep tracking in naturalistic settings with patients. It highlights measurement biases across devices, t","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e82465"},"PeriodicalIF":6.2,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12741658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145742704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms During Pregnancy by Using Real-World Data: Retrospective Cohort Study. 基于网络的认知行为治疗妊娠期抑郁症状的有效性:回顾性队列研究
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-11 DOI: 10.2196/73512
Asuka Takae, Natsu Sasaki, Kotaro Imamura, Daisuke Nishi

Background: Approximately 1 out of 5 pregnant women develops depression. Internet-based cognitive behavioral therapy (iCBT) is an effective way to treat not only depression but also mild depressive symptoms or subthreshold depression. While numerous iCBT programs have been developed and tested through randomized controlled trials for various mental health conditions and specific populations, research on their effectiveness and application in the real world remains limited.

Objective: This study aimed to examine the effectiveness of a previously developed iCBT program implemented in an existing app for improving depressive symptoms among pregnant women in a real-world setting.

Methods: The previously developed iCBT program for preventing perinatal depression was already implemented in an existing app called Luna Luna Baby by MTI Ltd. The app aims to provide information to pregnant women about pregnancy and babies, and potential users can download it from the Japanese version of the Apple App Store or Google Play Store without any fee. The program does not require any additional fees. The log data stored on the app identified iCBT program users and nonusers, allowing us to conduct this retrospective cohort study. Data from September 2022 to September 2024 were extracted from the app after anonymous processing. The primary outcome was the score on the self-reported Edinburgh Postnatal Depression Scale (EPDS), which participants answer by themselves on the app. The exposure group was defined as completers of all 6 modules of the iCBT program. The nonexposure group was defined as users who did not use any module of the program and matched the baseline characteristics of the exposure group. The change in EPDS score before and after using the program was compared using effect sizes, and repeated 2-way ANOVA was conducted to test the difference between the exposure and nonexposure groups.

Results: Data from 119 women who completed the iCBT program and 448 pair-matched controls were selected. The average EPDS scores at baseline were 7.24 (SD 5.30) in the exposure group and 7.25 (SD 5.18) in the nonexposure group. After using the iCBT program, the group mean EPDS scores changed by -0.69 (SD 4.92) and +0.99 (SD 5.56) over time in the exposure and nonexposure groups, respectively (Cohen d=0.31, 95% CI 0.11-0.51). The repeated 2-way ANOVA showed statistical significance in the interaction terms between the groups and the measurement time points (P=.04).

Conclusions: The previously developed iCBT program showed a significant effect with a modest effect size on decreasing depressive symptoms among pregnant women in a real-world setting. Future research should attempt to minimize dropouts and increase participation in the program.

背景:大约五分之一的孕妇患有抑郁症。基于网络的认知行为疗法(iCBT)不仅是治疗抑郁症的有效方法,而且也是治疗轻度抑郁症状或阈下抑郁症的有效方法。尽管针对各种心理健康状况和特定人群的随机对照试验已经开发和测试了许多iCBT项目,但对其有效性和在现实世界中的应用的研究仍然有限。目的:本研究旨在检验先前开发的iCBT程序在现有应用程序中实施的有效性,以改善现实世界中孕妇的抑郁症状。方法:之前开发的iCBT预防围产期抑郁症的程序已经在MTI有限公司现有的Luna Luna Baby应用程序中实施。该应用旨在为孕妇提供有关怀孕和婴儿的信息,潜在用户可以从日本版的苹果应用商店或谷歌Play商店免费下载。该计划不需要任何额外费用。存储在应用程序上的日志数据识别了iCBT程序的用户和非用户,使我们能够进行这项回顾性队列研究。从2022年9月到2024年9月的数据经过匿名处理后从应用程序中提取。主要结果是参与者在应用程序上自行报告的爱丁堡产后抑郁量表(EPDS)的分数。暴露组被定义为完成iCBT计划的所有6个模块。非暴露组定义为不使用任何程序模块且符合暴露组基线特征的用户。应用效应量比较应用程序前后EPDS评分的变化,并采用重复双因素方差分析(repeated two -way ANOVA)检验暴露组与非暴露组的差异。结果:数据来自119名完成iCBT项目的妇女和448名配对对照者。暴露组EPDS基线平均评分为7.24 (SD 5.30),非暴露组为7.25 (SD 5.18)。使用iCBT程序后,暴露组和非暴露组EPDS平均评分随时间的变化分别为-0.69 (SD 4.92)和+0.99 (SD 5.56) (Cohen d=0.31, 95% CI 0.11-0.51)。重复双因素方差分析显示,组间相互作用项和测量时间点间差异有统计学意义(P= 0.04)。结论:先前开发的iCBT项目在现实世界中显示出显著的效果,但效果大小适中,可以减轻孕妇的抑郁症状。未来的研究应尽量减少辍学率,并增加对该计划的参与。
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引用次数: 0
A Multiple Technology-Based Physical Activity Intervention for Latina Adolescents: Results From the Chicas Fuertes Randomized Controlled Trial. 基于多种技术的拉丁裔青少年体育活动干预:来自Chicas Fuertes随机对照试验的结果。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-11 DOI: 10.2196/71623
Jacob R Carson, Emily Greenstadt, Brittany Olivera, Shira Dunsiger, Michelle Zive, Michael Higgins, Job Godino, Bess Marcus, Dawn Meyer, Britta Larsen

Background: Latina adolescents report low levels of moderate-vigorous physical activity (MVPA) and high lifetime risk of lifestyle-related diseases. There is a lack of MVPA interventions targeted at this demographic despite documented health disparities. Given their high rates of mobile technology use, interventions delivered through mobile devices may be effective for this population.

Objective: This paper examines the efficacy of the Chicas Fuertes intervention in increasing MVPA across 6 months in Latina adolescents.

Methods: Participants were Latina adolescents (aged 13-18 years) in San Diego County who reported being underactive (<150 min/wk of MVPA). All participants received a wearable fitness tracker (Fitbit Inspire HR); half were randomly assigned to also receive the multimedia intervention. Intervention components included a personally tailored website, personalized texting based on Fitbit data, and social media. The primary outcome was change in minutes of weekly MVPA from baseline to 6 months, measured by ActiGraph accelerometers and the 7-Day Physical Activity Recall Interview. Changes in daily steps using Fitbit devices were also examined to test intervention efficacy.

Results: Participants (N=160) were 15.85 (SD 1.71) years old on average, and mostly second generation in the United States. For ActiGraph-measured MVPA, participants in the intervention group (n=83) increased from a median of 0 (IQR 0-24) minutes/week at baseline to 64 (IQR 19-72) minutes/week at 6 months compared to control participants, who showed increases from a median of 0 (IQR 0-26) at baseline to 41 (IQR 7-76) minutes/week at 6 months (P=.04). Self-reported MVPA increased in the intervention group from a median of 119 (IQR 62.5-185) minutes/week at baseline to 147 (IQR 96-181) minutes/week at 6 months compared to control participants, who showed increases from a median of 120 (IQR 48.8-235) at baseline to 124 (IQR 100-169) minutes/week at 6 months (P=.03). Steps also increased in both groups, with the intervention group showing significantly greater increases (P=.03).

Conclusions: This intervention was successful in using a tailored technology-based strategy to increase MVPA in Latina adolescents and provides a promising approach for addressing a key health behavior. Given the scalable technology used, future studies should focus on broad-scale dissemination to address health disparities.

背景:拉丁裔青少年报告低水平的中高强度体力活动(MVPA)和生活方式相关疾病的高终生风险。尽管有记录的健康差异,但缺乏针对这一人口的MVPA干预措施。鉴于移动技术的高使用率,通过移动设备提供的干预措施可能对这一人群有效。目的:研究Chicas Fuertes干预在6个月内增加拉丁裔青少年MVPA的效果。方法:参与者是圣地亚哥县报告运动不足的拉丁裔青少年(13-18岁)。结果:参与者(N=160)平均年龄15.85岁(SD 1.71),主要是美国的第二代。对于actigraphic测量的MVPA,与对照组相比,干预组(n=83)的参与者从基线时的中位数0 (IQR 0-24)分钟/周增加到6个月时的64 (IQR 19-72)分钟/周,对照组从基线时的中位数0 (IQR 0-26)增加到6个月时的41 (IQR 7-76)分钟/周(P= 0.04)。与对照组相比,干预组自我报告的MVPA从基线时的中位数119 (IQR 62.5-185)分钟/周增加到6个月时的147 (IQR 96-181)分钟/周,对照组从基线时的中位数120 (IQR 48.8-235)增加到6个月时的124 (IQR 100-169)分钟/周(P=.03)。两组患者的步数均有所增加,其中干预组的增加幅度更大(P=.03)。结论:该干预措施成功地使用了一种量身定制的基于技术的策略来增加拉丁裔青少年的MVPA,并为解决关键的健康行为提供了一种有希望的方法。鉴于所使用的可扩展技术,未来的研究应侧重于大规模传播,以解决健康差距。
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引用次数: 0
Obtaining Patient-Reported Outcome Data via a Home Patient Monitoring App: Development, Implementation, and Validation of Novel Interface Terminology. 通过家庭患者监测应用程序获取患者报告的结果数据:新接口术语的开发、实现和验证。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-11 DOI: 10.2196/65504
Lucia Sacchi, Giordano Lanzola, Silvana Quaglini, Nicole Veggiotti, Silvia Panzarasa, Valentina Tibollo, Matteo Terzaghi, Itske Fraterman, Savannah Glaser, Manuel Ottaviano, Vadzim Khadakou, Vitali Hisko, Mor Peleg, Sofie Wilgenhof, Henk Mallo, Alexandra Kogan, David Glasspool, Stephanie Medlock, Laura Del Campo, Matteo Gabetta, Mimma Rizzo, Laura Deborah Locati, Paola Gabanelli, Sara Demurtas, Andrea Premoli, Szymon Wilk
<p><strong>Background: </strong>Adverse events (AEs) related to cancer treatment represent a valuable source of information that can be used to adjust therapy for individual patients. The National Institutes of Health developed the Common Terminology Criteria for Adverse Events (CTCAE), a comprehensive standardized terminology for health care providers to consistently report AEs during patient visits. Mobile health technologies, in principle, also allow AEs to be self-reported by patients in between visits; however, the terminology poses challenges for them, both in selecting the correct symptom to report and in rating its severity. The National Institutes of Health developed the Patient-Reported Outcomes-CTACE as the patient-oriented companion of the CTCAE. However, it shows some weaknesses in completeness and precision when used for continuous home patient monitoring and for decision support.</p><p><strong>Objective: </strong>The aim of this paper is to propose a new terminology for reporting AEs that is easy for patients to use while also being clinically meaningful for health care providers and easily exploitable by decision support systems. Moreover, we aim to demonstrate its implementation and validation within the CAPABLE (Cancer Patients Better Life Experience) EU project.</p><p><strong>Methods: </strong>The development of the new terminology starts from the CTCAE, which includes a comprehensive list of signs and symptoms along with guidance for accurately grading their severity. Through a multistep, participatory approach involving both patients and health care providers, we reduced and adapted the AE list for patient-oriented apps. During the CAPABLE project, the proposed terminology was integrated into a mobile app and evaluated within a clinical pilot study involving 86 patients who were monitored through the app for at least 6 months, and a control cohort of 133 patients monitored using standard care practices.</p><p><strong>Results: </strong>The final terminology includes 124 AEs, 49 expressed as "present or absent," and 77 associated with 4 description levels. A mapping between the description levels and the original CTCAE grades enables running the decision support system embedded in the CAPABLE app. The pilot study demonstrated that the majority of the patients used the symptoms reporting functionality, sharing also 24 unique AEs that are not present in the Patient-Reported Outcomes-CTCAE. Symptoms reported using the proposed terminology allowed the enactment of the clinical practice guidelines included in the CAPABLE decision support tool, triggering 11 distinct recommendations.</p><p><strong>Conclusions: </strong>The results obtained from the clinical study support our claim regarding the need for a novel terminology for the self-reporting of AEs, characterized by ease of use, completeness, and clinical meaningfulness. Finally, by mapping our terminology to the CTCAE, we demonstrated that it is possible to exploit self-reported
背景:与癌症治疗相关的不良事件(ae)是一个有价值的信息来源,可用于调整个体患者的治疗。美国国立卫生研究院制定了不良事件通用术语标准(CTCAE),这是一个全面的标准化术语,供卫生保健提供者在患者就诊期间一致报告不良事件。原则上,移动卫生技术还允许患者在两次就诊之间自我报告ae;然而,这些术语给他们带来了挑战,既要选择正确的症状报告,也要对其严重程度进行评级。美国国立卫生研究院开发了患者报告结果- ctace,作为CTCAE的患者导向的伙伴。然而,当用于连续的家庭病人监测和决策支持时,它显示出一些完整性和准确性的弱点。目的:本文的目的是提出一个报告ae的新术语,该术语易于患者使用,同时对卫生保健提供者也具有临床意义,并且易于决策支持系统利用。此外,我们的目标是在CAPABLE(癌症患者更好的生活体验)欧盟项目中展示其实施和验证。方法:新术语的发展从CTCAE开始,其中包括体征和症状的综合列表以及准确分级其严重程度的指导。通过涉及患者和医疗服务提供者的多步骤、参与式方法,我们减少并调整了面向患者的应用程序AE列表。在CAPABLE项目中,提议的术语被整合到一个移动应用程序中,并在一项临床试点研究中进行评估,该研究涉及86名患者,通过该应用程序监测至少6个月,以及133名使用标准护理实践监测的对照患者。结果:最终的术语包括124个ae, 49个表达为“存在或不存在”,77个与4个描述级别相关。描述级别和原始CTCAE等级之间的映射使嵌入在CAPABLE应用程序中的决策支持系统能够运行。试点研究表明,大多数患者使用症状报告功能,还共享24个患者报告结果-CTCAE中不存在的独特ae。使用提议的术语报告的症状允许制定包括在CAPABLE决策支持工具中的临床实践指南,从而引发11项不同的建议。结论:从临床研究中获得的结果支持我们的主张,即需要一个新的术语来描述ae的自我报告,其特点是易于使用,完整性和临床意义。最后,通过将我们的术语映射到CTCAE,我们证明了利用自我报告的数据来触发符合临床实践指南的决策支持规则是可能的。
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引用次数: 0
The Challenge of Measuring Exercise: Advancing Metrological Barriers in Wearable Sensing. 测量运动的挑战:推进可穿戴传感的计量障碍。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-10 DOI: 10.2196/79347
Jennifer L Corso, Evan Peikon

Regular physical activity offers extensive health benefits, yet current consumer wearables struggle to accurately quantify these effects at an individualized level. Sensor performance often falls short due to susceptibility to interferences, nonstandardized validation, and reliance on indirect estimations. Further, sensors often cannot capture or account for disparities in measurement types, populations, and physiological or anatomical characteristics, nor can they account for how different exercise modalities affect results on a personalized scale. There is a drive for developers to refine the impact of how we measure the benefits of exercise, improving the usefulness of data through advanced optical modeling and spectroscopic applications. This review critically examines the shortcomings of prevailing noninvasive measurements and techniques used in common, commercially available fitness trackers and describes why it is difficult to quantify the effects of exercise as an individualized, quality-based metric. Next, we discuss newer sensing applications that attempt to curtail known limitations, some of which may unveil novel biometric insights through differentiated approaches, bridging gaps not only in technological advancement but also in physiological metrology. In conclusion, we believe that new sensing techniques should explore solutions beyond population-based statistics and aim to provide an individualized understanding of a person's response to exercise, while also reducing disparities in personalized health monitoring. The results could lead to a more effective understanding of exercise efficacy and its impact on performance management and clinical outcomes.

定期的体育锻炼可以带来广泛的健康益处,但目前的消费者可穿戴设备很难在个性化层面上准确量化这些影响。由于对干扰的敏感性、非标准化验证和依赖间接估计,传感器性能往往会下降。此外,传感器通常不能捕获或解释测量类型、人群和生理或解剖特征的差异,也不能解释不同的运动方式如何影响个性化规模的结果。开发人员有一种动力来改进我们如何衡量运动益处的影响,通过先进的光学建模和光谱应用来提高数据的有用性。这篇综述批判性地考察了普遍使用的非侵入性测量和技术的缺点,并描述了为什么难以将运动的效果量化为个性化的、基于质量的指标。接下来,我们将讨论新的传感应用,这些应用试图减少已知的限制,其中一些可能会通过不同的方法揭示新的生物识别见解,不仅在技术进步方面,而且在生理计量学方面弥合差距。总之,我们认为新的传感技术应该探索基于人口的统计之外的解决方案,旨在提供个人对运动反应的个性化理解,同时减少个性化健康监测的差异。研究结果可能会让我们更有效地了解运动功效及其对绩效管理和临床结果的影响。
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引用次数: 0
Unraveling the Factors Associated With Digital Health Intervention Uptake: Cross-Sectional Study. 揭示与数字健康干预吸收相关的因素:横断面研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-09 DOI: 10.2196/63896
Ilona Ruotsalainen, Mikko Valtanen, Riikka Kärsämä, Adil Umer, Hilkka Liedes, Suvi Parikka, Annamari Lundqvist, Kirsikka Aittola, Suvi Koivunen, Jussi Pihlajamäki, Anna-Leena Vuorinen, Jaana Lindström
<p><strong>Background: </strong>Chronic noncommunicable diseases (NCDs) remain a leading health challenge worldwide, and reducing modifiable lifestyle risk factors is a key prevention strategy. Digital health interventions (DHIs) offer scalable, cost-effective tools to support healthy behaviors, but concerns persist about their equitable reach and uptake across population groups.</p><p><strong>Objective: </strong>This study aimed to examine how socioeconomic factors, health status, lifestyle behaviors, and attitudes and experiences related to the use of electronic services (e-services) are associated with the uptake of a DHI.</p><p><strong>Methods: </strong>In this cross-sectional study, we invited (through mail or SMS) a subgroup of 6978 participants aged 20-74 years from the population-based Healthy Finland survey to take part in a DHI. The DHI, delivered via the web-based BitHabit app, aimed to support the adoption of healthy lifestyle habits. Uptake was defined as successful registration, agreeing to the terms of use, and accepting the invitation to participate. Predictor variables were drawn from national registry and self-reported survey data and included socioeconomic status, health indicators, lifestyle behaviors, and attitudes and experiences related to the use of e-services. Adjusted logistic regression models were used to identify significant predictors of DHI uptake.</p><p><strong>Results: </strong>Of the final sample of 6975 participants, 1287 (18.5%) started using the DHI. Uptake was significantly higher among women (adjusted odds ratio [aOR] 1.69, 95% CI 1.49-1.93), middle-aged individuals (aOR 1.47, 95% CI 1.21-1.79), and those with higher income (aORs 1.76-1.97, 95% CIs 1.37-2.59) and more years of education (aOR 1.10, 95% CI 1.08-1.12). Healthier lifestyle indicators, including better diet quality (aOR 1.07, 95% CI 1.04-1.10), less frequent smoking or nonsmoking (aORs 1.59-2.29, 95% CIs 1.08-3.12), sleep (aOR 0.58, 95% CI 0.37-0.86), higher functional capacity (aOR 1.06, 95% CI 1.02-1.11), and good overall current health (aOR 1.46, 95% CI 1.15-1.89), were associated with increased likelihood of DHI uptake. The strongest predictors were related to the use of e-services: Individuals who used e-services (aORs 2.48-6.08, 95% CIs 1.19-11.92) reported higher competence to use e-services (aORs 2.00-4.10, 95% CIs 1.44-5.92), had low concerns about data security (aORs 1.37-1.76, 95% CIs 1.03-2.33), believed in the benefits of digital services (aOR 1.04, 95% CI 1.02-1.05), and had better internet connections had higher odds of uptake.</p><p><strong>Conclusions: </strong>Our findings show that DHI uptake is associated with socioeconomic status, health and lifestyle factors, and, especially, individuals' experience and attitudes toward e-services. Individuals with lower education levels, lower income, and poorer health and lifestyle habits are less likely to adopt DHIs, raising concerns about potential digital health inequities. These resul
背景:慢性非传染性疾病(NCDs)仍然是世界范围内主要的健康挑战,减少可改变的生活方式风险因素是一项关键的预防策略。数字卫生干预措施(DHIs)提供了可扩展的、具有成本效益的工具来支持健康行为,但对其在人群中的公平覆盖和吸收仍然存在担忧。目的:本研究旨在探讨与使用电子服务(e-services)相关的社会经济因素、健康状况、生活方式行为、态度和经验如何与DHI的采用相关联。方法:在这项横断面研究中,我们(通过邮件或短信)邀请6978名年龄在20-74岁之间的芬兰健康人群调查参与者参加了DHI。该DHI通过基于网络的BitHabit应用程序发布,旨在支持人们养成健康的生活习惯。摄取被定义为成功注册,同意使用条款,并接受邀请参与。预测变量来自国家登记和自我报告的调查数据,包括社会经济地位、健康指标、生活方式行为以及与使用电子服务相关的态度和经验。采用调整后的逻辑回归模型来确定DHI摄取的显著预测因子。结果:在6975名参与者的最终样本中,1287名(18.5%)开始使用DHI。女性(调整比值比[aOR] 1.69, 95% CI 1.49-1.93)、中年人(aOR 1.47, 95% CI 1.21-1.79)、高收入(aOR 1.76-1.97, 95% CI 1.37-2.59)和受教育年限较高(aOR 1.10, 95% CI 1.08-1.12)人群的摄取明显较高。更健康的生活方式指标,包括更好的饮食质量(aOR 1.07, 95% CI 1.04-1.10)、更少吸烟或不吸烟(aOR 1.59-2.29, 95% CI 1.08-3.12)、睡眠(aOR 0.58, 95% CI 0.37-0.86)、更高的功能能力(aOR 1.06, 95% CI 1.02-1.11)和良好的整体健康状况(aOR 1.46, 95% CI 1.15-1.89),与DHI摄取可能性增加相关。最强的预测因子与电子服务的使用有关:使用电子服务的个人(aOR 2.48-6.08, 95% CI 1.19-11.92)报告了更高的使用电子服务的能力(aOR 2.00-4.10, 95% CI 1.44-5.92),对数据安全的担忧较低(aOR 1.37-1.76, 95% CI 1.03-2.33),相信数字服务的好处(aOR 1.04, 95% CI 1.02-1.05),并且更好的互联网连接具有更高的使用几率。结论:我们的研究结果表明,DHI的吸收与社会经济地位、健康和生活方式等因素有关,尤其是与个人对电子服务的体验和态度有关。受教育程度较低、收入较低、健康和生活习惯较差的个人不太可能采用DHIs,这引起了人们对潜在的数字健康不平等的担忧。这些结果强调需要制定有针对性的战略,以减少障碍,并确保在未来实施人类健康倡议时更公平地覆盖和参与。
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引用次数: 0
Exploring Age-Related Patterns in Smartphone Keystroke Dynamics Considering Temporal Variability: Cross-Sectional Study With AI-Based Analysis. 考虑时间变化的智能手机按键动力学中年龄相关模式的探索:基于人工智能分析的横断面研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-02 DOI: 10.2196/80094
Junhyung Moon, Yu Lim Huh, Hee Young Cho, Chaeyeon Kim, Hyeongrae Lee, Dong Pyo Jang, Baek Hwan Cho
<p><strong>Background: </strong>Keystroke dynamics on smartphones have emerged as a promising form of passive digital biomarker. While previous studies have explored their utility in several diseases and disorders, relatively few have examined how these dynamics change systematically with chronological age in the general population.</p><p><strong>Objective: </strong>This study aimed to investigate age-related patterns in mobile keystroke dynamics, with a particular focus on temporal variations throughout the day. By identifying behavioral signatures associated with different age groups, we further assess whether artificial intelligence-based models can accurately estimate chronological age using passively collected keystroke data.</p><p><strong>Methods: </strong>We conducted a field study involving 177 healthy adults in the Republic of Korea, collecting free-living smartphone typing logs over multiple weeks through a custom Android keyboard app (CodeRed Corp). For each keystroke, the app recorded press and release timestamps and key type, from which 43 behavioral features were extracted across categories of speed, frequency, and temporal variability. Weekly feature vectors were constructed at 3 temporal resolutions (6-hour intervals, daily, and weekly). In total, 8 artificial intelligence models, including random forest, TabNet, transformer, and long short-term memory, were trained with participant-wise 10-fold cross-validation. A custom loss function was introduced to reduce intraparticipant prediction variability. Descriptive statistics and ablation studies were conducted to assess behavioral trends and feature contributions.</p><p><strong>Results: </strong>The study included 177 participants (female: n=115; male: n=62) with a mean age of 28.8 (SD 11.1) years, all residing in the Republic of Korea. On average, data were collected for 25 weeks per participant, resulting in a dataset of more than 2.5 million typing sessions. Descriptive analysis revealed clear age-related differences. Younger participants typed faster and more frequently, while older participants showed slower and more variable typing. The long short-term memory model using the 6-hour interval median features achieved the best age estimation performance (mean absolute error 3.69 years, R<sup>2</sup>=0.71). When the customized loss function was applied, the model's performance further improved to a mean absolute error of 3.60, with a reduction in intraparticipant variability in estimated ages by 7.8%. Notably, feature importance analysis suggested that the early morning (midnight to 6 AM) and late evening (6 PM to midnight) periods may carry more age-discriminative keystroke patterns.</p><p><strong>Conclusions: </strong>Our findings demonstrated that smartphone keystroke dynamics reflect age-sensitive behavioral patterns, particularly when analyzed with fine-grained temporal resolution. While the primary goal was not age estimation per se, the ability to model these patterns highl
背景:智能手机上的击键动力学已经成为一种很有前途的被动数字生物标志物。虽然以前的研究已经探索了它们在几种疾病和失调中的效用,但相对较少的研究已经检查了这些动态如何随着一般人群的实际年龄而系统地变化。目的:本研究旨在调查手机按键动力学中与年龄相关的模式,特别关注全天的时间变化。通过识别与不同年龄组相关的行为特征,我们进一步评估基于人工智能的模型是否可以使用被动收集的击键数据准确估计实足年龄。方法:我们在韩国开展了一项涉及177名健康成年人的实地研究,通过定制的Android键盘应用程序(CodeRed Corp)收集了数周内自由生活的智能手机打字日志。对于每次击键,应用程序都会记录下按键和释放时间戳以及按键类型,并从中提取出43种行为特征,包括速度、频率和时间变化。每周特征向量以3种时间分辨率(6小时间隔、每日和每周)构建。共建立了随机森林、TabNet、transformer和长短期记忆等8个人工智能模型,并进行了10倍交叉验证。引入自定义损失函数来降低参与者内预测的可变性。描述性统计和消融研究用于评估行为趋势和特征贡献。结果:该研究包括177名参与者(女性:n=115;男性:n=62),平均年龄28.8 (SD 11.1)岁,均居住在大韩民国。平均而言,每位参与者的数据收集时间为25周,结果产生了超过250万次打字会话的数据集。描述性分析揭示了明显的年龄相关差异。年轻的参与者打字更快、更频繁,而年长的参与者打字速度更慢、更多变。使用6小时间隔中位数特征的长短期记忆模型的年龄估计性能最好(平均绝对误差3.69年,R2=0.71)。当应用自定义损失函数时,模型的性能进一步提高,平均绝对误差为3.60,估计年龄的参与者内部变异性降低了7.8%。值得注意的是,特征重要性分析表明,清晨(午夜至早上6点)和傍晚(下午6点至午夜)期间可能存在更多年龄歧视的击键模式。结论:我们的研究结果表明,智能手机的击键动态反映了年龄敏感的行为模式,特别是在进行细粒度时间分辨率分析时。虽然主要目标不是年龄估计本身,但建模这些模式的能力突出了击键动力学作为与年龄相关的功能特征的被动、不显眼的行为标记的潜力。这些见解可以为数字健康领域的未来应用提供信息,例如对年龄敏感的个性化或与年龄相关的衰退的早期检测,而无需任何主动用户输入。
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引用次数: 0
Health Motivation as a Predictor of mHealth Engagement Across BMI: Cross-Sectional Survey. 健康动机是BMI中移动健康参与的预测因子:横断面调查。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-01 DOI: 10.2196/71625
Shao-Hsuan Chang, Lung-Kun Yeh, Daishi Chen, Kae-Kuen Hu, Mei-Ching Yu, Ching-Mao Chang

Background: Digital health tools, such as mobile apps and wearable devices, have been widely adopted to support self-management of health behaviors. However, user engagement remains inconsistent, particularly among populations with varying BMI. While digital health technologies have the potential to promote healthier behaviors, little is known about how psychological and behavioral factors interact with BMI to influence use patterns.

Objective: This study aimed to explore the relationship between BMI and digital health technology use and to examine how factors such as health awareness, self-efficacy, and health motivation contribute to technology engagement.

Methods: A cross-sectional online survey was conducted from January 2024 to April 2024. A total of 184 valid questionnaire participants were included in this study. The questionnaire was measured on a 5-point Likert scale. Descriptive statistics, chi-square tests, and multiple regression analyses were applied.

Results: Of the participants, 38.6% (71/184) had a BMI<24 kg/m2, 42.4% (78/184) had a BMI between 24 and 29.9 kg/m2, and 19% (35/184) had a BMI≥30 kg/m2. Significant BMI differences were observed based on sex (P<.001) and age (P<.001) but not based on prior digital health tool use. Use rates for Bluetooth or Wi-Fi devices, wearables, and mobile apps were 32.1% (59/184), 38.6% (71/184), and 39.1% (72/184), respectively. A negative correlation between BMI and mobile app use frequency was identified (P=.02). Multiple regression analysis indicated that health motivation significantly predicted digital health use (P<.001), whereas health awareness, lifestyle, and self-efficacy did not.

Conclusions: Individuals with higher BMI reported a lower frequency of digital health tool use, potentially due to lower health motivation in the studied population. Health motivation was the strongest predictor of digital health engagement. Integrating personalized medical records into apps may enhance health motivation, thereby improving user engagement and promoting healthier behaviors in individuals with higher BMI.

背景:数字健康工具,如移动应用程序和可穿戴设备,已被广泛采用,以支持健康行为的自我管理。然而,用户粘性仍然不一致,特别是在不同BMI的人群中。虽然数字健康技术有可能促进更健康的行为,但人们对心理和行为因素如何与BMI相互作用以影响使用模式知之甚少。目的:本研究旨在探讨BMI与数字健康技术使用之间的关系,并研究健康意识、自我效能感和健康动机等因素如何影响技术参与。方法:于2024年1月至2024年4月进行横断面在线调查。本研究共纳入184份有效问卷。问卷采用李克特5分制进行测量。采用描述性统计、卡方检验和多元回归分析。结果:38.6%(71/184)的参与者BMI为2,42.4%(78/184)的参与者BMI在24 - 29.9 kg/m2之间,19%(35/184)的参与者BMI≥30 kg/m2。基于性别观察到显著的BMI差异(结论:BMI较高的个体报告数字健康工具使用频率较低,可能是由于研究人群中较低的健康动机。)健康动机是数字健康参与的最强预测因子。将个性化医疗记录集成到应用程序中可以增强健康动机,从而提高用户参与度,促进高BMI个体的健康行为。
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引用次数: 0
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JMIR mHealth and uHealth
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