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Smartphone App-Based Exercise for Pregnant Women in Indonesia: Quasi-Experimental Study on Physical Activity, Fear of Childbirth, and Quality of Life. 印度尼西亚孕妇基于智能手机app的锻炼:身体活动、分娩恐惧和生活质量的准实验研究
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-24 DOI: 10.2196/73105
Dewi Marfuah, Tukimin Bin Sansuwito, Rathimalar Ayakannu
<p><strong>Background: </strong>Pregnancy, a vital phase in a woman's life, entails immense physical, psychological, and emotional alterations that might affect maternal health. Physical activity during pregnancy improves health outcomes; however, adherence to the recommendation is low. Moreover, fear of childbirth (FoC) has a negative impact on maternal mental health and quality of life (QoL). Mobile health (mHealth) interventions, especially those delivered through smartphone-based exercise management apps, provide a scalable solution to improve maternal health outcomes.</p><p><strong>Objective: </strong>This study aims to assess the impact of an exercise management intervention based on a smartphone app on physical activity, FoC, and QoL in pregnant women in Indonesia.</p><p><strong>Methods: </strong>We used a quasi-experimental design with repeated measures, conducted at public health centers in West Java, Indonesia. A total of 240 pregnant women were recruited through convenience sampling and allocated to either an intervention group (n=120), which received a smartphone app-based exercise and behavioral program, or a control group (n=120), which received standard prenatal care. Data were collected at 3 time points: baseline measurement (T0), postintervention measurement (T1), and 1-month follow-up measurement (T2). The intervention targeted improvements in physical activity, reduction of FoC, and enhancement of QoL. Validated instruments were used to assess outcomes, including the Pregnancy Physical Activity Questionnaire (PPAQ), the Wijma Delivery Expectation Questionnaire Version A (WDEQ-A), and the Quality-of-Life Gravidarum (QOL-GRAV) scale. Statistical analyses were performed using repeated measures ANOVA with Bonferroni post hoc tests, and effect sizes were calculated using Cohen d.</p><p><strong>Results: </strong>The intervention group had significant increases in physical activity levels from T0 to T1 (Cohen d=0.65; P<.001) and from T0 to T2 (Cohen d=0.72, P<.001), whereas there were no significant changes in the control group. FoC scores were significantly lower at T1 (Cohen d=0.52; P<.001) and T2 (Cohen d=0.56; P<.001) compared to T0 in the intervention group, but no changes were observed in the control group. QoL scores increased significantly in the intervention group from T0 to T1 (Cohen d=0.60; P<.001) and from T0 to T2 (Cohen d=0.68; P<.001), while there were no significant changes noted in the control group.</p><p><strong>Conclusions: </strong>The exercise management intervention using the smartphone app was effective in increasing physical activity, reducing FoC, and improving QoL among pregnant women in Indonesia. The intervention represents a scalable and accessible mechanism through which maternal health can be improved in limited-resource contexts. Large-scale, long-term studies are needed to evaluate the sustainability of the benefits observed and the incorporation of mHealth solutions in standard prenatal management.</
背景:怀孕是妇女一生中至关重要的阶段,它会带来巨大的身体、心理和情感变化,可能会影响产妇的健康。怀孕期间的身体活动可改善健康状况;然而,遵守建议的情况很低。此外,分娩恐惧(FoC)对孕产妇心理健康和生活质量(QoL)产生负面影响。移动健康(mHealth)干预措施,特别是通过基于智能手机的运动管理应用程序提供的干预措施,为改善孕产妇健康结果提供了可扩展的解决方案。目的:本研究旨在评估基于智能手机应用程序的运动管理干预对印度尼西亚孕妇身体活动、FoC和生活质量的影响。方法:我们采用准实验设计,重复测量,在印度尼西亚西爪哇的公共卫生中心进行。通过方便抽样,共招募了240名孕妇,并将其分配到干预组(n=120)和对照组(n=120),干预组接受基于智能手机应用程序的锻炼和行为计划,对照组接受标准的产前护理。数据收集于3个时间点:基线测量(T0)、干预后测量(T1)和1个月随访测量(T2)。干预的目标是改善身体活动,减少FoC,提高生活质量。采用经验证的工具评估结局,包括妊娠体力活动问卷(PPAQ)、Wijma分娩期望问卷版本A (WDEQ-A)和妊娠生活质量(QOL-GRAV)量表。采用重复测量方差分析和Bonferroni事后检验进行统计分析,并使用Cohen d.计算效应量。结果:干预组从T0到T1的身体活动水平显著增加(Cohen d=0.65; p)。结论:使用智能手机应用程序的运动管理干预在增加印度尼西亚孕妇的身体活动,降低FoC和改善生活质量方面是有效的。该干预措施是一种可扩展和可获得的机制,在资源有限的情况下,通过这种机制可以改善孕产妇保健。需要进行大规模的长期研究,以评估所观察到的益处的可持续性,以及将移动健康解决方案纳入标准产前管理。
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引用次数: 0
The ManageHF Just-in-Time Adaptive Mobile Application Interventions to Promote Self-Management and Improve Outcomes in Heart Failure: A Randomized Controlled Trial. ManageHF即时适应性移动应用干预促进心力衰竭患者自我管理和改善预后:一项随机对照试验
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-19 DOI: 10.2196/74121
Michael P Dorsch, Mohamed S Ali, Amy Krambrink, Giselle Kolenic, Sabah Ganai, Juan Arzac, Xutong Zhang, Kaitlyn M Greer, Amit J Shah, Jennifer A Cowger, Gregory Ewald, Jo Ellen Rodgers, Dave Dixon, Todd M Koelling, Scott L Hummel

Background: Heart failure (HF) is a major healthcare challenge in the United States, with approximately 900,000 older adults hospitalized annually. Gaps in self-management, including unrecognized worsening symptoms and failure to adhere to dietary sodium restriction, can reduce quality of life and precipitate hospital admissions. Existing mHealth approaches to HF self-management have produced mixed results, highlighting the need for innovative strategies to improve post-discharge outcomes in at-risk patients.

Objective: The ManageHF trial aimed to evaluate the effectiveness of two just-in-time adaptive interventions (JITAIs) delivered via a mobile application to enhance HF self-management. The interventions focused on symptom recognition and lower dietary sodium restriction, with the goal of reducing readmissions and improving HRQOL over a 12-week period.

Methods: The trial was a 2x2 factorial, double-blind, randomized controlled study conducted across several U.S. institutions. Participants recently hospitalized for acute HF were randomized into four groups: both interventions, either intervention alone, or an active control. The primary outcome was a composite measure assessing time to all-cause death, time to first HF readmission, and HRQOL changes, using the Minnesota Living with Heart Failure Questionnaire (MLHFQ).

Results: Recruitment was hindered by the COVID-19 pandemic, leading to the early discontinuation of the trial. Of 62 participants enrolled, 43 completed the study. Participants were diverse, with a mean age of 55 years; 32% were female, and 55% were Black or African American. Most had HF with reduced ejection fraction . However, due to the early termination and small sample size, the ability to detect statistically significant differences was limited.

Conclusions: The ManageHF trial highlighted the potential of mobile health technology to support HF management, particularly in enhancing HRQOL. Future studies employing more effective recruitment and retention strategies are crucial for establishing the efficacy of these interventions with greater certainty.

Clinicaltrial:

背景:心力衰竭(HF)是美国主要的医疗保健挑战,每年约有90万老年人住院治疗。自我管理方面的差距,包括未被认识到的症状恶化和未能坚持饮食钠限制,可能会降低生活质量并导致住院。现有的心衰自我管理的移动健康方法产生了不同的结果,突出表明需要创新策略来改善高危患者的出院后预后。目的:ManageHF试验旨在评估通过移动应用程序提供的两种即时适应性干预(JITAIs)的有效性,以增强HF自我管理。干预措施侧重于症状识别和降低饮食钠限制,目标是在12周内减少再入院和改善HRQOL。方法:该试验是在美国几家机构进行的2x2因子、双盲、随机对照研究。最近因急性心衰住院的参与者被随机分为四组:两种干预,单独干预或积极对照。主要终点是使用明尼苏达心力衰竭生活问卷(MLHFQ)评估到全因死亡时间、首次心力衰竭再入院时间和HRQOL变化的综合测量。结果:新冠肺炎大流行阻碍了招募,导致试验提前终止。在62名参与者中,有43人完成了研究。参与者各不相同,平均年龄55岁;32%是女性,55%是黑人或非裔美国人。大多数心衰伴射血分数降低。然而,由于早期终止和小样本量,检测具有统计学意义差异的能力受到限制。结论:ManageHF试验强调了移动医疗技术支持心衰管理的潜力,特别是在提高HRQOL方面。采用更有效的招募和保留策略的未来研究对于更确定地确定这些干预措施的有效性至关重要。临床试验:
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引用次数: 0
Forging Online Community Among People in Recovery From Substance Use: Natural Language Processing and Deep-Learning Analysis of The Phoenix App User-Generated Data. 在药物使用恢复人群中建立在线社区:凤凰应用程序用户生成数据的自然语言处理和深度学习分析。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-19 DOI: 10.2196/68438
Danny Valdez, Katie M Heinrich, Beth Collinson, Aspen Streetman, Zach Sloan

Background: Mobile apps are powerful tools for promoting and sustaining healthy behaviors, including supporting diverse recovery pathways from substance use, including alcohol use disorder. Indeed, prior research strongly supports the notion that social connection through mobile platforms, supplemented by an in-person interaction, is vital in helping individuals strengthen their recovery and improve overall well-being and mental health. However, research into the digital footprints of mobile app users, as a strategy to assess app usage experiences in a recovery context, is lacking.

Objective: This study utilizes a dataset from The Phoenix app, a social media platform specifically designed for individuals impacted by substance use, including those in or seeking recovery, to identify core uses of the app, including how it is leveraged by members from a thematic and emotional valence context.

Methods: We applied natural language processing and deep learning methods to analyze a random sample of 19,685 posts. Analyses included the Bidirectional Encoder Representation from Transformers topic modeling tool to generate themes and a Valence Aware Dictionary and Sentiment Reasoner sentiment analysis to approximate emotional tone and mood from posts ranging from highly negative (-0.99) to highly positive (0.99).

Results: After removing duplicate and nonsensical posts, we retained a final sample size of 17,617 posts. Bidirectional Encoder Representation from Transformers topic modeling tool identified 10 topics (coherence score=0.48) within 2 overarching themes: (1) those related to engaging app members through in-person and online interactions (7 topics) and (2) as a forum to discuss more serious topics pertaining to substance use and mental health recovery (3 topics). Overall, the topics revealed a distinct and recurring theme of community support. Valence Aware Dictionary and Sentiment Reasoner sentiment analysis was 0.44 (SD 0.42), indicating highly positive posts, with only 429 (2.4%) being highly negative.

Conclusions: The study findings broadly show positive uses of The Phoenix app as a tool for social connections and community among people in recovery from substance use. With the high positive sentiment of posts, the app was distinct from other social media platforms (eg, X, Reddit, Facebook), which often feature a mix of highly positive and highly negative posts. Additional research is needed to confirm these results using a larger dataset and with comparative analysis of other recovery forums to contribute to the understanding of social media's role and function in changing health-related behaviors.

背景:移动应用程序是促进和维持健康行为的强大工具,包括支持从物质使用(包括酒精使用障碍)中恢复的多种途径。事实上,先前的研究强烈支持这样一种观点,即通过移动平台进行的社交联系,辅以面对面的互动,对于帮助个人加强康复,改善整体幸福感和心理健康至关重要。然而,对于手机应用用户的数字足迹的研究,作为在恢复环境中评估应用使用体验的策略,是缺乏的。目的:本研究利用凤凰应用程序的数据集,凤凰应用程序是一个专门为受药物使用影响的个人设计的社交媒体平台,包括那些正在或正在寻求恢复的人,以确定该应用程序的核心用途,包括成员如何从主题和情感价环境中利用它。方法:采用自然语言处理和深度学习方法对随机抽取的19685篇帖子进行分析。分析包括来自《变形金刚》主题建模工具的双向编码器表示(Bidirectional Encoder Representation)来生成主题,以及一个价值感知词典和情感推理器(Sentiment Reasoner)的情感分析,以从高度消极(-0.99)到高度积极(0.99)的帖子中近似情感基调和情绪。结果:在去除重复和无意义的帖子后,我们保留了17617个帖子的最终样本量。来自《变形金刚》主题建模工具的双向编码器表示在两个总体主题中确定了10个主题(一致性得分=0.48):(1)通过面对面和在线互动吸引应用程序成员的主题(7个主题);(2)作为讨论与物质使用和心理健康恢复有关的更严肃主题的论坛(3个主题)。总的来说,这些主题揭示了一个独特而反复出现的主题——社区支持。效价感知词典和情绪推理者情绪分析为0.44 (SD 0.42),表明高度积极的帖子,只有429(2.4%)是高度消极的。结论:研究结果广泛表明,凤凰应用程序作为一种工具,在从药物使用中恢复的人们之间建立社会联系和社区。由于帖子的积极情绪很高,这款应用与其他社交媒体平台(如X、Reddit、Facebook)不同,后者的帖子通常是高度积极和高度消极的混合。需要进一步的研究来证实这些结果,使用更大的数据集并与其他恢复论坛进行比较分析,以有助于理解社交媒体在改变与健康有关的行为方面的作用和功能。
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引用次数: 0
Identifying Time-Variant Predictors of Interest in Completing Brief Digital Mental Health Interventions Among Adult Survivors of Cancer: Ecological Momentary Assessment Study. 确定成年癌症幸存者完成简短数字心理健康干预的时变预测因素:生态瞬时评估研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-18 DOI: 10.2196/69244
Katharine E Daniel, James W Kinchen, Angela Chang, Patrick H Finan, Philip I Chow
<p><strong>Background: </strong>Digital microinterventions have strong potential to improve the lives of adults diagnosed with cancer. However, little is known about which types of digital microinterventions are most desired and how contextual factors may influence those preferences. This potentially limits guidance for personalized and timely digital microintervention delivery.</p><p><strong>Objective: </strong>This study aims to identify time-varying and person-level predictors of relative digital microintervention interest among adult survivors of cancer.</p><p><strong>Methods: </strong>We enrolled US adults within 5 years of a cancer diagnosis in a 5-week observational study using ecological momentary assessment. Participants (N=407) were asked 3 times a day for 5 weeks which of 9 brief, mobile-delivered interventions, if any, they would have been interested in completing within the past hour. Intervention options were (1) reducing worry, (2) reducing negative thoughts, (3) problem solving, (4) increasing positive emotions, (5) connecting with values, (6) guided relaxation, (7) getting support from others, (8) setting goals, and (9) something else. Multinomial models were used to identify demographic (ie, age), cancer-related (ie, treatment status), and psychological (ie, depression symptom severity, anxiety symptom severity, history of major depressive diagnosis, history of anxiety disorder diagnosis, and psychotherapy status) predictors of individual differences in modal intervention preference. Multilevel logistic and multilevel multinomial models were used to identify momentary negative affect, positive affect, and pain predictors of relative intervention interest.</p><p><strong>Results: </strong>Participants indicated interest in completing a digital microintervention in 87% (20,429/23,472) of completed surveys. The most frequently selected intervention option was guided relaxation (8611/20,429, 42%). Neither cancer treatment status (χ<sup>2</sup><sub>9</sub>=6.5; P=.69) nor psychotherapy status (χ<sup>2</sup><sub>9</sub>=14.0; P=.12) differentiated between modal intervention preferences. Participants with greater anxiety (χ<sup>2</sup><sub>9</sub>=35.1; P<.001) and depression symptom severity (χ<sup>2</sup><sub>9</sub>=23.0; P=.006) were less likely to modally endorse guided relaxation compared to other intervention options like increasing positive emotions, reducing negative thoughts, and getting support from others. Higher momentary negative affect and pain and lower momentary positive affect each predicted a greater likelihood to endorse interest in completing an intervention (vs not completing an intervention; P<.05) and to endorse interest in completing multiple interventions (vs only one; P<.001). Finally, higher momentary negative affect generally predicted greater interest in completing an intervention other than guided relaxation, whereas higher momentary pain generally predicted greater relative interest in guided relaxation.<
背景:数字微干预在改善成年癌症患者的生活方面具有强大的潜力。然而,对于哪种类型的数字微干预是最需要的,以及环境因素如何影响这些偏好,人们知之甚少。这可能会限制对个性化和及时的数字微干预提供的指导。目的:本研究旨在确定成年癌症幸存者相对数字微干预兴趣的时变和个人水平预测因素。方法:我们在一项为期5周的观察性研究中招募了被诊断为癌症的5年内的美国成年人,使用生态瞬时评估。参与者(N=407)在5周内每天被询问3次,如果有的话,他们有兴趣在过去一小时内完成9个简短的、移动交付的干预措施中的哪一个。干预选项有:(1)减少忧虑,(2)减少消极想法,(3)解决问题,(4)增加积极情绪,(5)与价值观联系,(6)引导放松,(7)获得他人支持,(8)设定目标,以及(9)其他事情。使用多项模型来确定人口统计学(即年龄)、癌症相关(即治疗状况)和心理(即抑郁症状严重程度、焦虑症状严重程度、重度抑郁诊断史、焦虑障碍诊断史和心理治疗状况)预测因素在模态干预偏好方面的个体差异。采用多水平逻辑模型和多水平多项模型来识别瞬时负面影响、积极影响和相对干预兴趣的疼痛预测因子。结果:87%(20,429/23,472)的参与者表示有兴趣完成数字微干预。最常选择的干预方案是引导放松(8611/ 20429,42%)。癌症治疗状态(χ29=6.5; P= 0.69)和心理治疗状态(χ29=14.0; P= 0.12)在模式干预偏好之间均无差异。焦虑程度较高的参与者(χ29=35.1; P29=23.0; P= 0.006)与其他干预方案(如增加积极情绪、减少消极想法和获得他人支持)相比,在模式上支持引导放松的可能性较小。较高的瞬时负面影响和疼痛以及较低的瞬时积极影响均预示着更大的可能性支持完成干预的兴趣(与不完成干预相比)。结论:成年癌症幸存者在人与人之间和人与人之间的数字微干预偏好不同。当癌症幸存者处于更大的情绪困扰时,单独的引导式放松不太有吸引力,但在应对疼痛增加的情况时可能更有吸引力。
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引用次数: 0
Digital Physiotherapeutic Ankle-Specific Training System for Patients With Chronic Ankle Instability Following Modified Brostrom Surgery: Noninferiority Randomized Controlled Trial at a Tertiary Grade A Trauma Center in China. 改良Brostrom手术后慢性踝关节不稳定患者的数字物理治疗踝关节特异性训练系统:中国三级创伤中心的非低质量随机对照试验。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-18 DOI: 10.2196/78307
Xiang Geng, Yilin Jin, Xu Wang, Xin Zhang, Yiming Lyu, Shengdi Lu, Xin Ma
<p><strong>Background: </strong>Functional rehabilitation is commonly used for patients with chronic ankle instability (CAI). Digital training (DT) systems have become increasingly popular in postoperative rehabilitation; however, their effectiveness for CAI patients after modified Brostrom surgery (MBS) is uncertain. Furthermore, specialized physiotherapy resources for CAI are limited in some regions, highlighting the need for effective digital home-based rehabilitation alternatives.</p><p><strong>Objective: </strong>This trial aimed to evaluate whether individually tailored physiotherapeutic ankle-specific training (PAST) delivered via a DT system is noninferior to conventional face-to-face physiotherapy in clinical outcomes and to compare their cost-effectiveness in CAI patients following MBS in China.</p><p><strong>Methods: </strong>We conducted a 2-arm, single-blinded (assessor), noninferiority randomized controlled trial at a tertiary hospital in Shanghai, China, from January 2022 to January 2024. A total of 84 postsurgery CAI patients were randomly assigned to a DT group (n=42), which received a 12-week individualized PAST program via a digital system, or a physiotherapy group (n=42), which received standard face-to-face physiotherapy for 12 weeks. Assessments were performed at baseline, 12 weeks, and 24 weeks postoperatively. The primary outcomes were 2 subscales of the Foot and Ankle Ability Measure, with a noninferiority margin of 8 points for Foot and Ankle Ability Measure-Activities of Daily Living (FAAM-ADL) and 9 points for Foot and Ankle Ability Measure-Sports (FAAM-S). Secondary outcomes included balance tests (time-in-balance, foot-lift, and star excursion balance), functional tests (ankle dorsiflexion range of motion, side-hop, and figure-8 hop), and quality of life (FAAM questionnaire). We also collected intervention costs to evaluate cost-effectiveness. Statistical analyses included between-group comparisons of outcomes and nonparametric bootstrapping to calculate incremental cost-effectiveness ratios.</p><p><strong>Results: </strong>Baseline characteristics were similar between groups (except for a difference in foot-lift test performance). By the 24-week follow-up, improvements in the primary outcomes were comparable between the DT and physiotherapy groups, with adjusted between-group differences of 0.36 (95% CI -1.01 to 1.72) for FAAM-ADL and 1.67 (95% CI -0.61 to 3.96) for FAAM-S. These differences fell within the predefined noninferiority margins, demonstrating noninferiority of the digital program. No significant between-group differences were observed in secondary outcomes (all P>.05). The average cost per patient was lower in the DT group (CNY 53,551; an exchange rate of US $1=CNY 7 was applied) than in the physiotherapy group (CNY 59,372), yielding an incremental cost of CNY -14,451 in favor of the digital intervention. The bootstrapped incremental cost-effectiveness ratios were CNY -16,396 for FAAM-ADL and CNY -114,1
背景:功能康复是治疗慢性踝关节不稳定(CAI)的常用方法。数字训练(DT)系统在术后康复中越来越受欢迎;然而,它们对改良Brostrom手术(MBS)后CAI患者的有效性尚不确定。此外,在一些地区,专门用于CAI的物理治疗资源有限,这突出了对有效的数字家庭康复替代方案的需求。目的:本试验旨在评估通过DT系统提供的个性化物理治疗踝关节特异性训练(PAST)在临床结果上是否优于传统面对面物理治疗,并比较它们在中国MBS后CAI患者中的成本效益。方法:我们于2022年1月至2024年1月在中国上海的一家三级医院进行了一项双组、单盲(评估者)、非劣效性随机对照试验。84例术后CAI患者被随机分为DT组(n=42)和物理治疗组(n=42), DT组通过数字系统接受为期12周的个性化PAST计划,物理治疗组(n=42)接受为期12周的标准面对面物理治疗。在基线、术后12周和术后24周进行评估。主要结果为足踝能力测量的2个分量表,足踝能力测量-日常生活活动(FAAM-ADL)非效度为8分,足踝能力测量-运动(FAAM-S)非效度为9分。次要结果包括平衡测试(平衡时间、抬脚和星移平衡)、功能测试(踝关节背屈运动范围、侧跳和8字形跳)和生活质量(FAAM问卷)。我们还收集了干预成本来评估成本效益。统计分析包括组间结果比较和非参数引导来计算增量成本-效果比。结果:两组之间的基线特征相似(除了脚举测试表现的差异)。在24周的随访中,DT组和物理治疗组的主要预后改善具有可比性,FAAM-ADL组调整后的组间差异为0.36 (95% CI -1.01至1.72),FAAM-S组调整后的组间差异为1.67 (95% CI -0.61至3.96)。这些差异落在预定义的非劣效性范围内,表明数字程序的非劣效性。次要结局组间无显著差异(均P < 0.05)。DT组每位患者的平均成本(53,551元人民币;汇率为1美元= 7元人民币)低于物理治疗组(59,372元人民币),因此数字干预的增量成本为-14,451元人民币。FAAM-ADL的自启动增量成本-效果比为-16,396元,FAAM-S的自启动增量成本-效果比为-114,131元,说明DT更具成本效益。结论:通过DT系统提供的个性化定制PAST在临床上优于传统的面对面物理治疗,并且更具成本效益,支持其作为MBS后CAI患者可行的康复选择。
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引用次数: 0
Improvement in Quality of Life After Early Interactive Human Coaching via a Mobile App in Postgastrectomy Patients With Gastric Cancer: Prospective Randomized Controlled Trial. 胃切除术后胃癌患者通过移动应用程序进行早期互动人类指导后生活质量的改善:前瞻性随机对照试验
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-18 DOI: 10.2196/75445
Bang Wool Eom, Mira Han, Hong Man Yoon, Young-Woo Kim, So Young Kim, Jin Myoung Oh, Gyung Ah Wie, Keun Won Ryu
<p><strong>Background: </strong>Patients undergoing gastrectomy usually experience postgastrectomy syndrome and face difficulties adapting to a regular diet. Human health coaching via a mobile app has recently been applied to patients with chronic metabolic diseases, with significant improvements being observed in clinical outcomes.</p><p><strong>Objective: </strong>This study aimed to compare the quality of life and nutritional outcomes of human health coaching via a mobile app with those of conventional face-to-face counseling in postgastrectomy patients with gastric cancer.</p><p><strong>Methods: </strong>This was a prospective randomized controlled trial, and patients were enrolled between May 2020 and August 2022. The mobile coaching group received health coaching that provides personalized advice based on self-recorded health data via a mobile app from assigned coaches for 3 months after discharge, and the conventional counseling group underwent dietary consultations with a clinical dietitian 1 and 3 months postoperatively. The primary end point for sample size calculation was the eating restriction score on the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire gastric cancer module 1 month postoperatively. Secondary end points included changes in other subscales of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and gastric cancer module, as well as nutritional outcomes assessed preoperatively and 1, 3, 6, and 12 months postoperatively.</p><p><strong>Results: </strong>Data from 88.9% (160/180) of enrolled patients were analyzed after excluding dropouts. In the mobile coaching group (n=76), 66% (n=50) of patients who used the mobile app for ≥8 weeks were classified as active users. No significant difference in eating restriction 1 month postoperatively was found between the mobile coaching and conventional counseling groups. However, the mobile coaching group reported less dyspnea during the entire period (P=.01), less eating restriction at 6 months (P=.045), and less negative body image 3 months postoperatively (P=.04) than the conventional counseling group (n=84). Exploratory subgroup analyses based on age, sex, and operation type indicated that younger patients (<60 years), female patients, and those who underwent distal gastrectomy had better quality of life from mobile coaching. In the mobile coaching group, exploratory subgroup analyses based on mobile activity showed that active users had a better global health status than inactive users (P=.005). However, no significant differences in body composition or nutritional parameters were observed between the mobile coaching and conventional counseling groups or between active and inactive users in the mobile coaching group.</p><p><strong>Conclusions: </strong>Although this trial did not show a significant difference in eating restriction 1 month postoperatively, human coaching via a mobile app was
背景:接受胃切除术的患者通常会经历胃切除术后综合征,并且难以适应正常的饮食。通过移动应用程序的人类健康指导最近被应用于慢性代谢性疾病患者,在临床结果中观察到显着改善。目的:本研究旨在比较通过移动应用程序进行人类健康指导与传统面对面咨询对胃切除术后胃癌患者的生活质量和营养结局的影响。方法:这是一项前瞻性随机对照试验,患者于2020年5月至2022年8月入组。移动辅导组在出院后3个月接受由指定教练通过移动应用程序根据自己记录的健康数据提供个性化建议的健康辅导,常规辅导组在术后1个月和3个月接受临床营养师的饮食咨询。计算样本量的主要终点是术后1个月欧洲癌症研究和治疗组织生活质量问卷胃癌模块的饮食限制评分。次要终点包括欧洲癌症研究和治疗组织生活质量问卷核心30和胃癌模块的其他亚量表的变化,以及术前和术后1、3、6和12个月评估的营养结果。结果:88.9%(160/180)的入组患者在排除退出后进行了数据分析。在移动教练组(n=76)中,66% (n=50)使用移动app≥8周的患者被归类为活跃用户。术后1个月,移动辅导组与常规辅导组在饮食限制方面无显著差异。然而,与传统咨询组(n=84)相比,移动训练组在整个期间报告的呼吸困难较少(P= 0.01), 6个月时的饮食限制较少(P= 0.045),术后3个月的负面身体形象较少(P= 0.04)。基于年龄、性别和手术类型的探索性亚组分析表明,更年轻的患者(结论:尽管该试验在术后1个月的饮食限制方面没有显示出显著差异,但在某些尺度上,与传统咨询相比,通过移动应用程序进行的人工指导与胃切除术后胃癌患者的症状更少有关。这种干预可能会帮助病人控制他们的症状并适应他们的饮食。试验注册:ClinicalTrials.gov NCT04394585;https://clinicaltrials.gov/study/NCT04394585。
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引用次数: 0
Effectiveness of mHealth Interventions to Improve Follow-Up and Management Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis. 移动健康干预改善实体器官移植受者随访和管理的有效性:系统回顾和荟萃分析。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-17 DOI: 10.2196/69795
Xiaohong Lin, Haiya Sun, Jiaxin Fang, Zhufeng Han, Zhenshan Ding, Jianding Guo, Lei Dong, Xiangru Li, Hongxia Liu
<p><strong>Background: </strong>Effective follow-up and management after organ transplantation are crucial for transplant recipients. Mobile health (mHealth) interventions have emerged as a significant approach for facilitating follow-up and management. However, there is a lack of systematic reviews and meta-analyses of their effectiveness.</p><p><strong>Objective: </strong>This study aimed to systematically review and synthesize evidence regarding the effectiveness of mHealth interventions in enhancing follow-up and management for transplant recipients.</p><p><strong>Methods: </strong>This study included both randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs) that compared the effects of mHealth interventions with usual care in transplant recipients by searching PubMed, Web of Science, Scopus, Embase, CINAHL, and CENTRAL from database inception to June 2025. The primary outcomes included self-care ability, medical regimen adherence, self-monitoring, communication and counseling, medication adherence, physical activity, nutrition, all-cause mortality, complications, rehospitalization, and emergency and outpatient department visits. The risk of bias for each study was assessed using version 2 of the Cochrane risk-of-bias tool for RCTs and the Risk of Bias in Nonrandomized Studies of Interventions tool for NRSIs. Data extraction and quality assessment were conducted by 2 reviewers independently. Data synthesis was conducted using Review Manager. Both a meta-analysis and a narrative synthesis were carried out.</p><p><strong>Results: </strong>A total of 23 studies (n=15, 65% RCTs and n=8, 35% NRSIs) with 2022 transplant recipients were included. Compared to the control group, mHealth interventions significantly improved self-care ability (mean difference 14.49, 95% CI 9.61-19.36; P<.001) and reduced rehospitalization (odds ratio [OR] 0.49, 95% CI 0.34-0.71; P<.001). The meta-analysis demonstrated no statistically significant difference in mortality rates (OR 0.73, 95% CI 0.39-1.35; P=.31), rejection (OR 0.55, 95% CI 0.25-1.19; P=.13), or infection (OR 0.33, 95% CI 0.06-1.82; P=.20) between the mHealth intervention and control groups. The narrative synthesis indicated that mHealth interventions could effectively promote adherence to medical regimens and medications, facilitate self-monitoring, and improve communication and consultation.</p><p><strong>Conclusions: </strong>mHealth interventions significantly improved self-care ability and reduced rehospitalization rates among organ transplant recipients. However, these interventions did not demonstrate a significant effect on all-cause mortality or complications. mHealth interventions showed potential benefits for various self-management behaviors in organ transplant recipients, but these findings need to be further verified. Future research should prioritize high-quality studies that investigate the impact of mHealth on physical activity, nutrition, and other patien
背景:器官移植后有效的随访和管理对移植受者至关重要。移动保健(mHealth)干预措施已成为促进后续行动和管理的重要方法。然而,缺乏对其有效性的系统评价和荟萃分析。目的:本研究旨在系统回顾和综合有关移动健康干预措施在加强移植受者随访和管理方面有效性的证据。方法:本研究包括随机对照试验(rct)和非随机干预研究(NRSIs),通过检索PubMed、Web of Science、Scopus、Embase、CINAHL和CENTRAL数据库,从数据库建立到2025年6月,比较移动健康干预与移植受者常规护理的效果。主要结局包括自我护理能力、医疗方案依从性、自我监测、沟通和咨询、药物依从性、身体活动、营养、全因死亡率、并发症、再住院、急诊和门诊就诊。每项研究的偏倚风险均采用Cochrane rct风险偏倚工具和非随机干预研究工具进行评估。数据提取和质量评价由2名审稿人独立完成。使用Review Manager进行数据综合。进行了meta分析和叙事综合。结果:共纳入23项研究(n=15, 65% rct和n=8, 35% NRSIs),共2022例移植受者。与对照组相比,移动健康干预显著提高了自我保健能力(平均差值14.49,95% CI 9.61-19.36);结论:移动健康干预显著提高了器官移植受者的自我保健能力,降低了再住院率。然而,这些干预措施并未显示出对全因死亡率或并发症的显著影响。移动健康干预显示了器官移植受者各种自我管理行为的潜在益处,但这些发现需要进一步验证。未来的研究应优先考虑高质量的研究,调查移动健康对身体活动、营养和其他以患者为中心的结果的影响。试验注册:国际注册系统评价和荟萃分析协议平台INPLASY202480101;https://inplasy.com/inplasy-2024-8-0101/.International注册报告标识符(irrid): RR2-10.37766/inplasy2024.8.0101。
{"title":"Effectiveness of mHealth Interventions to Improve Follow-Up and Management Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis.","authors":"Xiaohong Lin, Haiya Sun, Jiaxin Fang, Zhufeng Han, Zhenshan Ding, Jianding Guo, Lei Dong, Xiangru Li, Hongxia Liu","doi":"10.2196/69795","DOIUrl":"10.2196/69795","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Effective follow-up and management after organ transplantation are crucial for transplant recipients. Mobile health (mHealth) interventions have emerged as a significant approach for facilitating follow-up and management. However, there is a lack of systematic reviews and meta-analyses of their effectiveness.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to systematically review and synthesize evidence regarding the effectiveness of mHealth interventions in enhancing follow-up and management for transplant recipients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study included both randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs) that compared the effects of mHealth interventions with usual care in transplant recipients by searching PubMed, Web of Science, Scopus, Embase, CINAHL, and CENTRAL from database inception to June 2025. The primary outcomes included self-care ability, medical regimen adherence, self-monitoring, communication and counseling, medication adherence, physical activity, nutrition, all-cause mortality, complications, rehospitalization, and emergency and outpatient department visits. The risk of bias for each study was assessed using version 2 of the Cochrane risk-of-bias tool for RCTs and the Risk of Bias in Nonrandomized Studies of Interventions tool for NRSIs. Data extraction and quality assessment were conducted by 2 reviewers independently. Data synthesis was conducted using Review Manager. Both a meta-analysis and a narrative synthesis were carried out.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 23 studies (n=15, 65% RCTs and n=8, 35% NRSIs) with 2022 transplant recipients were included. Compared to the control group, mHealth interventions significantly improved self-care ability (mean difference 14.49, 95% CI 9.61-19.36; P&lt;.001) and reduced rehospitalization (odds ratio [OR] 0.49, 95% CI 0.34-0.71; P&lt;.001). The meta-analysis demonstrated no statistically significant difference in mortality rates (OR 0.73, 95% CI 0.39-1.35; P=.31), rejection (OR 0.55, 95% CI 0.25-1.19; P=.13), or infection (OR 0.33, 95% CI 0.06-1.82; P=.20) between the mHealth intervention and control groups. The narrative synthesis indicated that mHealth interventions could effectively promote adherence to medical regimens and medications, facilitate self-monitoring, and improve communication and consultation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;mHealth interventions significantly improved self-care ability and reduced rehospitalization rates among organ transplant recipients. However, these interventions did not demonstrate a significant effect on all-cause mortality or complications. mHealth interventions showed potential benefits for various self-management behaviors in organ transplant recipients, but these findings need to be further verified. Future research should prioritize high-quality studies that investigate the impact of mHealth on physical activity, nutrition, and other patien","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e69795"},"PeriodicalIF":6.2,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12756658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Fit Between the Outputs of Freely Available Medication Adherence Apps and Users' Needs: Mixed Methods Study. 探索免费药物依从性应用程序输出与用户需求之间的契合度:混合方法研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-16 DOI: 10.2196/68919
Kirstin Messner, Vanessa Sutter, Samuel Allemann, Isabelle Arnet
<p><strong>Background: </strong>Medication nonadherence is a significant barrier to therapy success. Smartphone apps represent reasonable tools for simple adherence-enhancing interventions. Many adherence apps are available in app stores with diverse content, quality, and outputs. We define "output of an adherence app" as the processing and visualization of data recorded by the user and related to adherence. In 2016, Santo et al defined 5 desirable features in the output of adherence apps: tracking history, charts, statistics, rewards, and an exportable file. With this, a reference point to evaluate outputs of adherence apps was delivered. Identifying and fulfilling users' needs are essential when developing an adherence app for patients' self-management and professional adherence services, such as therapy support provided by health care professionals (HCPs).</p><p><strong>Objective: </strong>We aimed to investigate the smartphone app market regarding desirable features in the outputs, explore the users' needs, and evaluate the concordance.</p><p><strong>Methods: </strong>We searched for smartphone adherence apps in the 2 largest commercial app repositories by using keywords. Search results were screened for eligibility by applying inclusion and exclusion criteria. Eligible, freely available apps were tested regarding desirable features in their output. We conducted 2 focus groups and a cross-sectional online survey to explore users' needs. Survey participants rated their desire for features on a 7-point Likert scale. Focus groups were analyzed using the previously reported framework method. Descriptive statistics were calculated by median and IQR or mean and SD. We compared survey subgroups with a 2-tailed t test. A P value <.05 was considered statistically significant.</p><p><strong>Results: </strong>We screened 80 apps for eligibility and included 9 in our analyses. All desirable features were present, with tracking history being the most frequent feature (in 8/9 apps). Other desirable features were observed in 3 or fewer of the apps. Eight individuals participated in the 2 focus groups. During the focus groups, a total of 13 categories of desired features emerged. All 5 desirable features were rated as important in adherence apps. Three additional features were mentioned: (1) professional feedback regarding therapy or intake course, (2) additional recommendations based on intake course, and (3) option to discuss the data with an HCP. A total of 42 individuals participated in the online survey. Tracking history was the most desired (mean rating of 5.29) and rewards the least desired feature (mean rating of 2.81) in the output. There was ambivalence regarding professional feedback, statistics, and charts. Participants with or without regular medication use showed no significant differences.</p><p><strong>Conclusions: </strong>The outputs delivered by freely available smartphone adherence apps only partly match users' needs. Users showed a speci
背景:药物依从性是治疗成功的一个重要障碍。智能手机应用程序是简单的增强依从性干预的合理工具。应用商店中有许多具有不同内容、质量和输出的坚持应用程序。我们将“依从应用的输出”定义为对用户记录的与依从相关的数据进行处理和可视化。2016年,Santo等人定义了坚持应用输出中的5个理想功能:跟踪历史、图表、统计、奖励和可导出文件。由此,提供了一个评估依从性应用程序输出的参考点。在为患者自我管理和专业依从性服务(如卫生保健专业人员提供的治疗支持)开发依从性应用程序时,确定和满足用户需求至关重要。目的:我们旨在调查智能手机应用市场中输出的理想功能,探索用户需求,并评估一致性。方法:我们使用关键词在2个最大的商业应用程序库中搜索智能手机粘附应用程序。通过应用纳入和排除标准筛选搜索结果的合格性。对合格的、免费的应用程序进行了测试,以确定其输出中的理想功能。我们进行了两个焦点小组和一个横断面在线调查,以探索用户的需求。调查参与者以7分的李克特量表为自己对特征的渴望打分。使用先前报道的框架方法对焦点小组进行分析。描述性统计采用中位数和IQR或平均值和SD计算。我们用双尾t检验比较调查亚组。结果:我们筛选了80个应用程序,并将其中9个纳入我们的分析。所有理想的功能都出现了,跟踪历史记录是最常见的功能(在8/9的应用程序中)。其他令人满意的功能在3个或更少的应用程序中被观察到。8个人参加了两个焦点小组。在焦点小组讨论期间,总共出现了13类期望的功能。在坚持应用程序中,所有5个理想功能都被评为重要的。另外三个特征被提到:(1)关于治疗或摄入过程的专业反馈,(2)基于摄入过程的额外建议,(3)与HCP讨论数据的选项。共有42人参与了在线调查。跟踪历史是最理想的(平均评分5.29),奖励输出中最不理想的特征(平均评分2.81)。对于专业的反馈、统计数据和图表,存在矛盾心理。服用或不服用常规药物的参与者没有显著差异。结论:免费提供的智能手机依从性应用程序提供的输出仅部分满足用户需求。用户对使用HCP解释他们的数据表现出特别的兴趣。因此,依从性应用程序不能替代HCP,但可以用于增强当前患者的护理。
{"title":"Exploring the Fit Between the Outputs of Freely Available Medication Adherence Apps and Users' Needs: Mixed Methods Study.","authors":"Kirstin Messner, Vanessa Sutter, Samuel Allemann, Isabelle Arnet","doi":"10.2196/68919","DOIUrl":"10.2196/68919","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Medication nonadherence is a significant barrier to therapy success. Smartphone apps represent reasonable tools for simple adherence-enhancing interventions. Many adherence apps are available in app stores with diverse content, quality, and outputs. We define \"output of an adherence app\" as the processing and visualization of data recorded by the user and related to adherence. In 2016, Santo et al defined 5 desirable features in the output of adherence apps: tracking history, charts, statistics, rewards, and an exportable file. With this, a reference point to evaluate outputs of adherence apps was delivered. Identifying and fulfilling users' needs are essential when developing an adherence app for patients' self-management and professional adherence services, such as therapy support provided by health care professionals (HCPs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;We aimed to investigate the smartphone app market regarding desirable features in the outputs, explore the users' needs, and evaluate the concordance.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We searched for smartphone adherence apps in the 2 largest commercial app repositories by using keywords. Search results were screened for eligibility by applying inclusion and exclusion criteria. Eligible, freely available apps were tested regarding desirable features in their output. We conducted 2 focus groups and a cross-sectional online survey to explore users' needs. Survey participants rated their desire for features on a 7-point Likert scale. Focus groups were analyzed using the previously reported framework method. Descriptive statistics were calculated by median and IQR or mean and SD. We compared survey subgroups with a 2-tailed t test. A P value &lt;.05 was considered statistically significant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We screened 80 apps for eligibility and included 9 in our analyses. All desirable features were present, with tracking history being the most frequent feature (in 8/9 apps). Other desirable features were observed in 3 or fewer of the apps. Eight individuals participated in the 2 focus groups. During the focus groups, a total of 13 categories of desired features emerged. All 5 desirable features were rated as important in adherence apps. Three additional features were mentioned: (1) professional feedback regarding therapy or intake course, (2) additional recommendations based on intake course, and (3) option to discuss the data with an HCP. A total of 42 individuals participated in the online survey. Tracking history was the most desired (mean rating of 5.29) and rewards the least desired feature (mean rating of 2.81) in the output. There was ambivalence regarding professional feedback, statistics, and charts. Participants with or without regular medication use showed no significant differences.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The outputs delivered by freely available smartphone adherence apps only partly match users' needs. Users showed a speci","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e68919"},"PeriodicalIF":6.2,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12754584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and Preliminary Effectiveness of a Mobile App-Based Personalized Exercise Program in Older Patients With Chronic Knee Osteoarthritis: Pilot Randomized Controlled Trial. 基于移动应用程序的个性化运动方案在老年慢性膝骨关节炎患者中的可行性和初步效果:随机对照试验。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-16 DOI: 10.2196/71073
Yu Jin Im, Jihong Choi, Sol-A Choi, Jeong-Yi Kwon, Jong Geol Do

Background: Knee osteoarthritis is a prevalent cause of disability among older adults, emphasizing the need for effective and accessible self-management strategies. Mobile app-based personalized exercise programs predominantly overcome the barriers associated with traditional approaches.

Objective: This study aimed to evaluate the feasibility and preliminary efficacy of a 6-week mobile app-based self-exercise program that incorporates a multimonitoring system, weekly progress tracking, and dynamic exercise adjustments used by physiotherapists, and compares them with those of a conventional paper-based self-exercise program in older patients with chronic knee osteoarthritis.

Methods: A total of 29 participants aged ≥60 years with chronic knee pain and radiographic evidence of osteoarthritis were randomized at a 2:1 ratio to either the intervention (19/29, 66%; mobile app-based program) or control (10/29, 34%; paper-based program) group. The mobile app delivered a personalized exercise program, which was tailored by physiotherapists based on remote monitoring of patient-reported symptoms. Feasibility outcomes included retention, adherence, and satisfaction rates, as well as safety. Preliminary clinical outcomes included changes from baseline to 6 weeks in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score, Numeric Rating Scale (NRS) pain, and other functional measures.

Results: A total of 26 participants (n=16, 62% intervention and n=10, 38% control) completed the 6-week assessment, with retention rates of 84% and 100%, respectively. No adverse events were reported. Adherence was high in the intervention group, with 69% exercising ≥5 days per week and 88% reporting high satisfaction. The intervention group exhibited significant reductions in the WOMAC total score (median change -11.00, 95% CI -23.00 to -2.50; P=.01) and NRS pain score (mean change -2.12, 95% CI -3.13 to -1.11; P<.001).

Conclusions: The mobile app-based personalized exercise program was feasible, safe, and well-accepted among older patients with knee osteoarthritis. High adherence and satisfaction support the practicality of this approach, and preliminary improvements in pain and function suggest potential clinical benefit. A larger, adequately powered trial is warranted to confirm the effectiveness of digital self-exercise interventions for knee osteoarthritis management.

背景:膝关节骨性关节炎是老年人致残的普遍原因,强调需要有效和可及的自我管理策略。基于移动应用的个性化锻炼计划主要克服了与传统方法相关的障碍。目的:本研究旨在评估一项为期6周的基于移动应用程序的自我锻炼计划的可行性和初步效果,该计划包括多监测系统、每周进度跟踪和物理治疗师使用的动态运动调整,并将其与传统的基于纸张的自我锻炼计划进行比较。方法:共有29名年龄≥60岁的慢性膝关节疼痛和骨关节炎影像学证据的参与者按2:1的比例随机分为干预组(19/29,66%;基于移动应用程序的方案)或对照组(10/29,34%;基于纸张的方案)。移动应用程序提供了一个个性化的锻炼计划,由物理治疗师根据患者报告的症状远程监测量身定制。可行性结果包括保留、依从性、满意度以及安全性。初步临床结果包括西安大略省和麦克马斯特大学骨关节炎指数(WOMAC)总分、数字评定量表(NRS)疼痛和其他功能测量从基线到6周的变化。结果:共有26名参与者完成了为期6周的评估,其中干预组为16名,占62%,对照组为10名,占38%,保留率分别为84%和100%。无不良事件报告。干预组的依从性很高,69%的人每周锻炼≥5天,88%的人报告高满意度。干预组WOMAC总分(中位数变化-11.00,95% CI -23.00至-2.50;P= 0.01)和NRS疼痛评分(中位数变化-2.12,95% CI -3.13至-1.11;P)显著降低。结论:基于移动应用程序的个性化运动方案在老年膝关节骨性关节炎患者中是可行、安全且被广泛接受的。高依从性和满意度支持了这种方法的实用性,并且疼痛和功能的初步改善表明了潜在的临床益处。有必要进行更大规模、更有力的试验,以证实数字化自我锻炼干预对膝关节骨关节炎管理的有效性。
{"title":"Feasibility and Preliminary Effectiveness of a Mobile App-Based Personalized Exercise Program in Older Patients With Chronic Knee Osteoarthritis: Pilot Randomized Controlled Trial.","authors":"Yu Jin Im, Jihong Choi, Sol-A Choi, Jeong-Yi Kwon, Jong Geol Do","doi":"10.2196/71073","DOIUrl":"10.2196/71073","url":null,"abstract":"<p><strong>Background: </strong>Knee osteoarthritis is a prevalent cause of disability among older adults, emphasizing the need for effective and accessible self-management strategies. Mobile app-based personalized exercise programs predominantly overcome the barriers associated with traditional approaches.</p><p><strong>Objective: </strong>This study aimed to evaluate the feasibility and preliminary efficacy of a 6-week mobile app-based self-exercise program that incorporates a multimonitoring system, weekly progress tracking, and dynamic exercise adjustments used by physiotherapists, and compares them with those of a conventional paper-based self-exercise program in older patients with chronic knee osteoarthritis.</p><p><strong>Methods: </strong>A total of 29 participants aged ≥60 years with chronic knee pain and radiographic evidence of osteoarthritis were randomized at a 2:1 ratio to either the intervention (19/29, 66%; mobile app-based program) or control (10/29, 34%; paper-based program) group. The mobile app delivered a personalized exercise program, which was tailored by physiotherapists based on remote monitoring of patient-reported symptoms. Feasibility outcomes included retention, adherence, and satisfaction rates, as well as safety. Preliminary clinical outcomes included changes from baseline to 6 weeks in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score, Numeric Rating Scale (NRS) pain, and other functional measures.</p><p><strong>Results: </strong>A total of 26 participants (n=16, 62% intervention and n=10, 38% control) completed the 6-week assessment, with retention rates of 84% and 100%, respectively. No adverse events were reported. Adherence was high in the intervention group, with 69% exercising ≥5 days per week and 88% reporting high satisfaction. The intervention group exhibited significant reductions in the WOMAC total score (median change -11.00, 95% CI -23.00 to -2.50; P=.01) and NRS pain score (mean change -2.12, 95% CI -3.13 to -1.11; P<.001).</p><p><strong>Conclusions: </strong>The mobile app-based personalized exercise program was feasible, safe, and well-accepted among older patients with knee osteoarthritis. High adherence and satisfaction support the practicality of this approach, and preliminary improvements in pain and function suggest potential clinical benefit. A larger, adequately powered trial is warranted to confirm the effectiveness of digital self-exercise interventions for knee osteoarthritis management.</p>","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e71073"},"PeriodicalIF":6.2,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tailoring mHealth for Healthy Aging: Focus Group Study With Retirement-Age Adults. 为健康老龄化量身定制移动医疗:针对退休年龄成年人的焦点小组研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-15 DOI: 10.2196/70051
Paula Collazo-Castiñeira, Rocío Rodríguez-Rey, Alfonso J Cruz-Jentoft, Somaya Ben Allouch, Doris Eglseer, Josje Schoufour, Eva Topinková, Peter J M Weijs, Yves Boirie, Macarena Sánchez-Izquierdo

Background: The adoption of mobile health (mHealth) technologies among older adults remains significantly lower than in younger populations, despite their potential to promote healthier lifestyles and mitigate age-related health risks.

Objective: This study aims to explore the perspectives of retirement-age adults on mHealth interventions, identifying factors that influence their adoption, such as persuasive elements in the app design and psychological techniques.

Methods: A qualitative focus group study was conducted with 19 Spanish participants recruited from urban community settings in Madrid, Spain (mean age 61.5 years; 15/19, 79% women). Participants discussed their attitudes, barriers, and preferences for mHealth tools. Focus groups were recorded, transcribed, and coded using an iterative process to ensure rigorous data analysis. An abductive approach was followed, using the persuasive design principles framework and the behavior change techniques' taxonomy, and representing any theme outside those frameworks.

Results: Participants expressed generally positive attitudes toward mHealth tools, favoring intuitive, user-friendly designs that are minimally time-demanding. However, significant barriers also emerged, such as low digital literacy and concerns about technology dependence. Key design preferences (persuasive design principles) and psychological techniques (behavior change techniques) were deemed beneficial, with preferred features such as tailored and meaningful goal-setting, self-monitoring, positive feedback (eg, congratulating messages after achieving a goal; social rewards), and a moderated use of notifications and prompts. Participants also stressed the importance of age-appropriate recommendations (eg, suggested diets for their age and characteristics) and design (eg, accessible, easy-to-use interfaces and human-like communication). Additionally, some preferences appeared to be culturally grounded (eg, rejection of anglicisms and the desire for locally relevant content, such as suggested activities specific to Madrid). Social support mechanisms, such as group activities and peer interactions through mHealth, were seen as critical for fostering motivation and engagement.

Conclusions: mHealth interventions for this population should offer accessible and easy-to-use interfaces along with initial tutorials, facilitating an easy onboarding to overcome low digital literacy, thereby enhancing both usability and initial adoption. Furthermore, by providing meaningful, tailored content (eg, personalized diets and goals) and social features that foster peer connection (eg, user chats or organized activities), these tools may better support sustained engagement over time.

背景:尽管移动医疗(mHealth)技术有可能促进更健康的生活方式并减轻与年龄相关的健康风险,但老年人对移动医疗(mHealth)技术的采用仍明显低于年轻人。目的:本研究旨在探讨退休年龄成年人对移动医疗干预的看法,确定影响其采用的因素,如应用程序设计中的说服因素和心理技巧。方法:从西班牙马德里的城市社区招募19名西班牙参与者进行定性焦点小组研究(平均年龄61.5岁;15/19,79%为女性)。与会者讨论了他们对移动医疗工具的态度、障碍和偏好。使用迭代过程对焦点小组进行记录、转录和编码,以确保严格的数据分析。采用诱导性方法,使用劝导式设计原则框架和行为改变技术的分类法,并表示这些框架之外的任何主题。结果:参与者普遍对移动医疗工具持积极态度,倾向于直观、用户友好的设计,且时间要求最低。然而,也出现了重大障碍,例如低数字素养和对技术依赖的担忧。关键的设计偏好(有说服力的设计原则)和心理技巧(行为改变技巧)被认为是有益的,首选的功能包括量身定制和有意义的目标设定、自我监控、积极反馈(例如,实现目标后的祝贺信息、社会奖励),以及适度使用通知和提示。与会者还强调了与年龄相适应的建议(例如,针对他们的年龄和特征提出的饮食建议)和设计(例如,可访问的、易于使用的界面和人性化的沟通)的重要性。此外,一些偏好似乎是有文化基础的(例如,拒绝使用英语和希望提供与当地相关的内容,例如建议的马德里特定活动)。社会支持机制,如小组活动和通过移动医疗进行的同伴互动,被视为促进动机和参与的关键。结论:针对这一人群的移动医疗干预措施应提供可访问和易于使用的界面以及初始教程,促进易于上手,以克服数字素养低的问题,从而提高可用性和初始采用率。此外,通过提供有意义的、量身定制的内容(例如,个性化的饮食和目标)和促进同伴联系的社交功能(例如,用户聊天或有组织的活动),这些工具可能会更好地支持长期的持续参与。
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