Pub Date : 2026-01-28DOI: 10.1016/j.jcmg.2025.12.008
Alexander C Razavi,Omar Dzaye,Harpreet S Bhatia,Viola Vaccarino,Anurag Mehta,Jerome I Rotter,Xiuqing Guo,Kent D Taylor,Jie Yao,Xiaohui Li,Stephen S Rich,Matthew J Budoff,Michael Y Tsai,Ron Blankstein,Michael D Shapiro,Khurram Nasir,Sotirios Tsimikas,Roger S Blumenthal,Seamus P Whelton,Michael J Blaha,Laurence S Sperling
{"title":"Modeling Benefit of Aspirin According to Lp(a) and Coronary Artery Calcium: MESA.","authors":"Alexander C Razavi,Omar Dzaye,Harpreet S Bhatia,Viola Vaccarino,Anurag Mehta,Jerome I Rotter,Xiuqing Guo,Kent D Taylor,Jie Yao,Xiaohui Li,Stephen S Rich,Matthew J Budoff,Michael Y Tsai,Ron Blankstein,Michael D Shapiro,Khurram Nasir,Sotirios Tsimikas,Roger S Blumenthal,Seamus P Whelton,Michael J Blaha,Laurence S Sperling","doi":"10.1016/j.jcmg.2025.12.008","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.12.008","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"82 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146072986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-12DOI: 10.1016/j.jcmg.2025.11.009
Jacob Abdaem,Dina Labib,Rhys Beaudry,Augustine Amakiri,Steven Dykstra,Yuanchao Feng,Melanie King,Jacqueline Flewitt,Danielle A Southern,Matthew T James,Stephen B Wilton,Carmen P Lydell,Andrew G Howarth,Bryan J Har,James A White,Robert J H Miller
BACKGROUNDViability testing is frequently used in patients with ischemic cardiomyopathy (ICM). However, its role in guiding revascularization decisions remains unclear.OBJECTIVESThis study aimed to evaluate the associations between a novel, segmentally registered viability and vascular jeopardy score and mortality following revascularization.METHODSThe study included patients with ICM, defined as obstructive coronary artery disease and LVEF <50%, undergoing cardiac magnetic resonance and invasive coronary angiography between 2015 and 2022. Segmental viability was defined as scar transmurality ≤50% detected by cardiac magnetic resonance. Spatially matched distributions of vascular perfusion jeopardy were established at the time of angiography by using a patient-specific coronary anatomy tree and lesion reporting algorithm. Interactions between viability extent, coronary artery disease severity, the novel marker of jeopardized but viable myocardium, and early revascularization were assessed using propensity score-adjusted time-to-event models for mortality.RESULTSOf 941 patients (mean age 65 years; 81% male), 193 underwent early revascularization. During a median follow-up of 4.8 years, 168 deaths occurred. There were no interactions between the number of viable segments and revascularization (interaction HR: 1.09; P = 0.211) or between the Duke jeopardy score and revascularization (interaction HR: 0.93; P = 0.245) with respect to future mortality. However, a significant interaction was identified for the number of jeopardized but viable segments (interaction HR: 0.91; P = 0.008). Patients with ≥3 jeopardized but viable segments experienced significantly lower mortality following early revascularization (propensity score-adjusted HR: 0.55; P = 0.015).CONCLUSIONSPatient-specific coronary tree-based reporting to define jeopardized but viable myocardium accurately is clinically feasible and identifies ICM patients who experience lower mortality from early revascularization.
{"title":"Patient-Specific Registration of Segmental Jeopardy and Viability: Novel Method to Guide Revascularization in Ischemic Cardiomyopathy.","authors":"Jacob Abdaem,Dina Labib,Rhys Beaudry,Augustine Amakiri,Steven Dykstra,Yuanchao Feng,Melanie King,Jacqueline Flewitt,Danielle A Southern,Matthew T James,Stephen B Wilton,Carmen P Lydell,Andrew G Howarth,Bryan J Har,James A White,Robert J H Miller","doi":"10.1016/j.jcmg.2025.11.009","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.11.009","url":null,"abstract":"BACKGROUNDViability testing is frequently used in patients with ischemic cardiomyopathy (ICM). However, its role in guiding revascularization decisions remains unclear.OBJECTIVESThis study aimed to evaluate the associations between a novel, segmentally registered viability and vascular jeopardy score and mortality following revascularization.METHODSThe study included patients with ICM, defined as obstructive coronary artery disease and LVEF <50%, undergoing cardiac magnetic resonance and invasive coronary angiography between 2015 and 2022. Segmental viability was defined as scar transmurality ≤50% detected by cardiac magnetic resonance. Spatially matched distributions of vascular perfusion jeopardy were established at the time of angiography by using a patient-specific coronary anatomy tree and lesion reporting algorithm. Interactions between viability extent, coronary artery disease severity, the novel marker of jeopardized but viable myocardium, and early revascularization were assessed using propensity score-adjusted time-to-event models for mortality.RESULTSOf 941 patients (mean age 65 years; 81% male), 193 underwent early revascularization. During a median follow-up of 4.8 years, 168 deaths occurred. There were no interactions between the number of viable segments and revascularization (interaction HR: 1.09; P = 0.211) or between the Duke jeopardy score and revascularization (interaction HR: 0.93; P = 0.245) with respect to future mortality. However, a significant interaction was identified for the number of jeopardized but viable segments (interaction HR: 0.91; P = 0.008). Patients with ≥3 jeopardized but viable segments experienced significantly lower mortality following early revascularization (propensity score-adjusted HR: 0.55; P = 0.015).CONCLUSIONSPatient-specific coronary tree-based reporting to define jeopardized but viable myocardium accurately is clinically feasible and identifies ICM patients who experience lower mortality from early revascularization.","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"29 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145956052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.jcmg.2025.12.003
Eike Nagel
{"title":"Stress CMR in ISCHEMIA: Function in Its Best Form.","authors":"Eike Nagel","doi":"10.1016/j.jcmg.2025.12.003","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.12.003","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"29 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.jcmg.2025.12.006
Robert S Zhang,Jonathan W Weinsaft
{"title":"Just When We Thought Viability Was in Jeopardy.","authors":"Robert S Zhang,Jonathan W Weinsaft","doi":"10.1016/j.jcmg.2025.12.006","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.12.006","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"56 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-05DOI: 10.1016/j.jcmg.2025.12.005
Andre La Gerche, Stephanie J. Rowe
{"title":"Moving From Eyeball Assessment to Quantification of the Right Ventricular “Hot Spot” in Arrhythmogenic Cardiomyopathy","authors":"Andre La Gerche, Stephanie J. Rowe","doi":"10.1016/j.jcmg.2025.12.005","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.12.005","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145902492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-05DOI: 10.1016/j.jcmg.2025.12.004
Paul A. Grayburn
{"title":"Impaired Right Ventricular Function After Transcatheter Treatment of Tricuspid Regurgitation","authors":"Paul A. Grayburn","doi":"10.1016/j.jcmg.2025.12.004","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.12.004","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"98 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145902487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jcmg.2025.07.003
Sarah Malik MD , Doosup Shin MD , Emma Caron BSc, Rick H.J.A. Volleberg MD, Koshiro Sakai MD, PhD, Carlos Collet MD, PhD, Evan Shlofmitz DO, Allen Jeremias MD, MSc, Ziad A. Ali MD, DPhil , Omar K. Khalique MD
{"title":"Validation of Coronary Stent Measurements Using Photon-Counting Detector Computed Tomography","authors":"Sarah Malik MD , Doosup Shin MD , Emma Caron BSc, Rick H.J.A. Volleberg MD, Koshiro Sakai MD, PhD, Carlos Collet MD, PhD, Evan Shlofmitz DO, Allen Jeremias MD, MSc, Ziad A. Ali MD, DPhil , Omar K. Khalique MD","doi":"10.1016/j.jcmg.2025.07.003","DOIUrl":"10.1016/j.jcmg.2025.07.003","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 1","pages":"Pages 126-129"},"PeriodicalIF":15.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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