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Evolution of Chemical Contaminant and Toxicology Studies, Part 1 - An Overview 化学污染物的演变和毒理学研究,第1部分-概述
Pub Date : 2003-12-15 DOI: 10.1071/SP03001
D. Jolley, G. O'Brien, J. Morrison
The study of environmental chemical contaminants and their toxicological effects has changed dramatically over the last 50 years. Initially studies concentrated on trying to identify what contaminants were actually present and to develop quantitative methods to determine the concentrations (total) present. Health impacts were often investigated independently in medical research centres. With improving analytical techniques, studies of the speciation of contamina nts began and the specific forms that were creating the major problems were gradually identified. Continuing improvements in analytical chemistry, together with a move towards more integrated and multidisciplinary research now sees chemists, biologists, toxicologists and health researchers working closely in teams to identify the specific agents of major concern and their pathways, transformations and mode of action. These changes in approach are reviewed. Issues that still require significant research such as cumulative impacts are also discussed.
近50年来,环境化学污染物及其毒理学效应的研究发生了巨大变化。最初的研究集中在试图确定实际存在的污染物,并开发定量方法来确定存在的浓度(总数)。医疗研究中心经常独立调查对健康的影响。随着分析技术的改进,开始了对污染物种类的研究,并逐渐确定了造成主要问题的具体形式。分析化学的不断改进,加上朝着更加综合和多学科研究的方向发展,现在化学家、生物学家、毒理学家和卫生研究人员紧密合作,以确定主要关注的具体制剂及其途径、转化和作用方式。本文对这些方法上的变化进行了回顾。还讨论了仍需要进行重大研究的问题,如累积影响。
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引用次数: 4
Cloud-to-Ground lightning location using TOGA of sferics 云对地闪电定位使用TOGA的服务
Pub Date : 2003-12-15 DOI: 10.1071/SP03013
V. Ramachandran, Sushi I Kumar, Anol Kishore
Lightning measurements have been extensively utilised by power companies, metereological offices as well as by the scientific community in general. As opposed to the Intra-Cloud (IC) discharge, the Cloud – to – Ground (CG) lightning stroke $ a major safety hazard. In CG lightning stoke, the stepped leader decending from the base of a thundercloud triggers the first return stroke. This stroke is responsible for most of the charge transfer within few tens of microseconds causing a current of tens of kA. In this report, we present a novel CG stroke location accuracy of ≈2km.
闪电测量已被电力公司、气象机构以及科学界广泛使用。与云内(IC)放电相反,云对地(CG)雷击是一个主要的安全隐患。在CG雷暴中,从雷云底部下降的梯级先导触发第一次回击。在几十微秒内,这种冲程负责大部分的电荷转移,造成几十kA的电流。在本报告中,我们提出了一种新的CG冲程定位精度≈2km。
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引用次数: 3
Survival of Escherichia coli in a tropical estuary 大肠杆菌在热带河口的生存
Pub Date : 2003-12-15 DOI: 10.1071/SP03008
A. Chandran, A. Hatha
The survival of Escherichia coli in tropical estuarine water has been studied under controlled laboratory conditions using microcosms. The survival has been assessed in terms of various self purifying factors of the natural waters such as biological, chemical and physical factors. The biological factors considered included competition from other microorganisms, predation by protozoa and coliphages. The suitability of the chemical composition of estuarine water has been studied under chemical factors and negative impact of sunlight has been studied under physical factors. The results revealed that sunlight exerted maximum negative impact, followed by biotic factors contained in the estuarine water. However, the chemical composition of the estuarine water is found to be suitable for the growth and survival of E. coli. The injury exerted by each of the above factors was also evaluated by using a selective and non-selective medium in conjunction. It was found that sunlight resulted in 100% injury of the cells as the cells failed to develop in a selective medium. While, sunlight resulted in the extinction of 90% of the E. coli cells within the first two hours of exposure, biotic factors took nearly 24 hours to remove the same amount of population.
在控制的实验室条件下,利用微生物研究了大肠杆菌在热带河口水中的生存。从自然水体的生物、化学、物理等各种自净因素对其生存进行了评价。考虑的生物学因素包括来自其他微生物的竞争,原生动物和噬菌体的捕食。在化学因素下研究了河口水化学成分的适宜性,在物理因素下研究了阳光的负面影响。结果显示,阳光对环境的负面影响最大,其次是河口水体中的生物因素。然而,发现河口水的化学成分适合大肠杆菌的生长和存活。通过使用选择性和非选择性培养基,还评估了上述每种因素所造成的伤害。结果发现,在选择性培养基中,由于细胞不能发育,太阳光对细胞的伤害率为100%。在阳光照射的前两个小时内,90%的大肠杆菌细胞消失,而生物因素则需要近24小时才能清除相同数量的大肠杆菌。
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引用次数: 24
Modelling the effect of vertical transmission in the dynamics of HIV/AIDS in an age-structured population 模拟艾滋病毒/艾滋病在年龄结构人群中的垂直传播动态的影响
Pub Date : 2003-12-15 DOI: 10.1071/SP03016
J. Mugisha, L. Luboobi
We use a continuous age-structured model of McKendrick-von-Foerster type to derive a two-age groups HIV/AIDS epidemic model. In the analysis of the model, keen interest is put on the role of vertical transmission in the dynamics of the spread of the epidemic. The model is analysed in two scenarios: the case when the force of infection is a constant and the case when we have it as a mass action. In the first case, the only possible equilibrium is the endemic equilibrium. In this situation, we show that if all babies born to infected mothers are HIV-free we have the basic reproductive number R0 = 0 and as such the epidemic will die out. In the second case, we show that both the disease-free and endemic equilibrium points exist. We also derive conditions for their stability.
我们使用McKendrick-von-Foerster型的连续年龄结构模型,推导出两个年龄组的HIV/AIDS流行模型。在对模型的分析中,人们对垂直传播在流行病传播动力学中的作用非常感兴趣。该模型在两种情况下进行了分析:感染力是恒定的情况和我们将其作为集体行动的情况。在第一种情况下,唯一可能的平衡是地方性平衡。在这种情况下,我们表明,如果受感染母亲所生的所有婴儿都没有艾滋病毒,我们的基本生殖数R0 = 0,因此这种流行病将会消失。在第二种情况下,我们证明了无病平衡点和地方病平衡点都存在。我们还推导出它们稳定的条件。
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引用次数: 7
Nutrient levels in sea and river water along the Coral Coast of Viti Levu, Fiji 斐济维提岛珊瑚海岸沿岸海水和河水的营养水平
Pub Date : 2003-12-15 DOI: 10.1071/SP03007
L. Mosley, W. Aalbersberg
Nutrient (nitrate and phosphate) levels potentially damaging to coral reefs have been detected at several sites along the Coral Coast of Viti Levu, Fiji. Nutrient concentrations were determined using standard techniques on an autoanalyser capable of measuring to sub-micromolar levels. The mean nitrate level for 34 seawater samples was 1.69 mM and the mean phosphate level was 0.21 mM which exceeded levels considered to be harmful to coral reef ecosystems (>1.0 mM N, >0.1 mM P). It is proposed that these elevated nutrient levels coupled with overfishing of herbivore species have contributed to the recent widespread growth of macro -algae species along this coast. Nutrient levels were highest at sites located near hotels and other populated sites. At sites not significantly influenced by human activity, levels were comparable to that of non-polluted sites elsewhere in Fiji. Concentrations of nutrients in rivers along the coast were generally higher than in seawater. Urgent action is needed at community, regional and government levels to try and reduce the nutrient inputs to this coast.
在斐济维提岛珊瑚海岸的几个地点检测到可能对珊瑚礁造成损害的营养物质(硝酸盐和磷酸盐)水平。在自动分析仪上使用标准技术测定营养浓度,能够测量到亚微摩尔水平。34个海水样本的平均硝酸盐含量为1.69 mM,平均磷酸盐含量为0.21 mM,超过了对珊瑚礁生态系统有害的水平(>1.0 mM N, >0.1 mM P)。这些营养水平的升高加上草食性物种的过度捕捞是近年来大型藻类物种在该海岸广泛生长的原因。在酒店和其他人口密集的地点附近,营养水平最高。在未受人类活动显著影响的场址,其水平与斐济其他地方未受污染的场址相当。沿岸河流的营养物质浓度普遍高于海水。需要在社区、地区和政府层面采取紧急行动,努力减少流入这一海岸的营养物质。
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引用次数: 55
Methane Concentration in Fiji Air: A Study of its Emission Trends and Source Strengths 斐济空气中甲烷浓度:其排放趋势和源强度的研究
Pub Date : 2003-12-15 DOI: 10.1071/SP03004
F. Mani, K. Koshy, M. Maata
In this study we have developed an in house capacity at the Chemistry Department, the University of the South Pacific, to analyze methane in ambient air to a precision of 1.5% using a custom converted Gas Chromatograph with FID detector. The technical support to develop this capacity was provided by our overseas partner, National Institute of Water and Atmospheric Research (NIWA). The air samples were collected from known sources of methane such as the digester at the sewage treatment plant, rubbish dump, wetlands, sugar cane burning in the western side of Viti Levu, geothermal emission in Vanua Levu, rice farms and cattle farms from September 2001 to June 2002 and were analyzed. Through inter-laboratory measurements involving NIWA a mean drift of 0.8% was obtained. The methane concentration in the ambient air has a seasonal cycle with a minimum during late January and a maximum during the July to August period. The digester at the sewage plant recorded the maximum concentration of approximately 70 ppmv followed by Lami rubbish dump with values ranging from 4.37 – 13.35 ppmv. The data from cattle farms, wetlands, rice farms and hot springs recorded emissions in the range of 2.00 – 5.11 ppmv, 1.85 – 4.25 ppmv, 1.77 – 2.62 ppmv and 2.06 – 1.90 ppmv respectively.
在这项研究中,我们在南太平洋大学化学系开发了一个内部能力,使用带有FID检测器的定制转换气相色谱仪分析环境空气中的甲烷,精度为1.5%。发展这种能力的技术支持是由我们的海外合作伙伴——国家水与大气研究所(NIWA)提供的。从2001年9月至2002年6月,从污水处理厂的沼气池、垃圾场、湿地、维提岛西侧的甘蔗燃烧、瓦努瓦岛的地热排放、稻田和牛场等已知的甲烷来源收集空气样本并进行分析。通过涉及NIWA的实验室间测量,平均漂移为0.8%。环境空气中甲烷浓度具有季节性循环,1月下旬最小,7 ~ 8月最大。污水厂的沼气池录得最高浓度约70 ppmv,其次是拉米垃圾场,浓度介乎4.37至13.35 ppmv。来自牛场、湿地、稻田和温泉的数据分别记录了2.00 - 5.11 ppmv、1.85 - 4.25 ppmv、1.77 - 2.62 ppmv和2.06 - 1.90 ppmv的排放量。
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引用次数: 1
Evolution of chemical contaminant and toxicology studies, part 2 - case studies of Selenium and Arsenic 化学污染物的演变和毒理学研究,第2部分:硒和砷的案例研究
Pub Date : 2003-12-15 DOI: 10.1071/SP03002
G. O'Brien, D. Jolley, J. Morrison
As the second of a two part series discussing the evolution of the field of environmental toxicology, this paper presents two case studies: selenium and arsenic. Developments over several decades in the understanding of the behaviour of arsenic and selenium in different chemical forms in various compartments of the environment are discussed. Selenium was initially thought to be toxic, but later investigations showed it to be an essential micronutrient with a variety of biochemical functions, and, importantly, that there is a very narrow gap between the essential and the toxic body burden. Arsenic, on the other hand, has not yet had an essential role established, but enjoys an interesting and notorious history of usage. Arsenic contamination of the drinking water supplies for many millions of people has been a major catalyst for much research into understanding arsenic chemistry in aquifer systems and also arsenic metabolism and toxicity. The relationships between chemical form, bioavailability, toxicity and metabolism of these two semi-metals are being established, especially with use of sophisticated and sensitive analytical instrumentation and biochemical techniques.
作为讨论环境毒理学领域演变的两部分系列的第二部分,本文介绍了两个案例研究:硒和砷。讨论了几十年来对不同化学形式的砷和硒在不同环境中的行为的理解的发展。硒最初被认为是有毒的,但后来的研究表明,它是一种必需的微量营养素,具有多种生化功能,而且,重要的是,必需和有毒的身体负担之间的差距非常小。另一方面,砷尚未确立其重要作用,但其使用历史有趣而臭名昭著。数百万人的饮用水受到砷污染,这是了解含水层系统中砷化学以及砷代谢和毒性的许多研究的主要催化剂。这两种半金属的化学形态、生物利用度、毒性和代谢之间的关系正在建立,特别是使用精密和敏感的分析仪器和生化技术。
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引用次数: 3
Concentration of 7Be in surface air at Suva, Fiji 斐济苏瓦地表空气中7Be的浓度
Pub Date : 2003-12-15 DOI: 10.1071/SP03003
S. Garimella, K. Koshy, Shusendra Singh
A high-volume air sampler and a high-resolution gamma-ray spectrometer have been used during the period 1999-2000 at the University of the South Pacific to measure the activity of 7Be in the surface air at Suva, the capital city of Fiji. The measurements indicate that the average concentration of 7Be in surface air is about 1.6 mBq m-3, which agrees closely with the corresponding values reported for other Pacific islands in the region. 7Be shows a significant correlation with nitrate in the atmosphere. This could imply long-range transport of anthropogenically-derived continental material to Fiji or the intrusion of nitrogen species from the stratosphere to surface air.
1999-2000年期间,在南太平洋大学使用了一台大容量空气采样器和一台高分辨率伽马射线光谱仪来测量斐济首都苏瓦地表空气中7Be的活动。测量结果表明,表层空气中7Be的平均浓度约为1.6 mBq m-3,这与该地区其他太平洋岛屿报告的相应值非常吻合。be与大气中硝酸盐有显著的相关性。这可能意味着人为产生的大陆物质向斐济的远距离运输,或者氮物种从平流层侵入到地面空气。
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引用次数: 6
A fuzzy legal reasoner for university decision support 高校决策支持的模糊法律推理
Pub Date : 2003-12-15 DOI: 10.1071/SP03014
D. Sharma, S. Behari
Deciding on university student disciplinary cases against stipulated rules and case facts an interesting problem for artificial intelligence. Reasoning with fuzzy rules and facts adds to the problem complexity. This paper discusses the various characteristics of the problem and presents a design and an implementation of a prototype that is modeled as a fuzzy expert system. Some test results are presented and the experience gained from the project is discussed. Some future work is also suggested to further strengthen the prototype to include a formal case specification and interaction language, and the possible drawing and use of relevant information from a knowledge base of previous cases.
根据规定规则和案件事实对大学生违纪案件进行判决是人工智能研究的一个有趣问题。用模糊的规则和事实进行推理会增加问题的复杂性。本文讨论了该问题的各种特点,并提出了一个原型的设计和实现,该原型被建模为一个模糊专家系统。给出了一些试验结果,并讨论了从工程中获得的经验。未来的一些工作还建议进一步加强原型,包括正式的案例规范和交互语言,并可能从以前的案例知识库中绘制和使用相关信息。
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引用次数: 0
Trace metal levels in drinking water on Viti Levu, Fiji Islands 斐济群岛维提岛饮用水中的微量金属含量
Pub Date : 2003-12-15 DOI: 10.1071/SP03006
Sarabjeet Singh, L. Mosley
Drinking water samples from several major source intakes and reticulation end points on Viti Levu, Fiji Islands were analysed for trace metal (As, Cd, Cr, Cu, Hg, Pb, Zn) content. The objective of the study was to determine if metal concentrations were within the World Health Organisation (WHO) guidelines. The concentrations of metals were determined using various atomic absorption techniques (flame, graphite furnace, hydride generation). In th e source waters, concentrations of trace metals were generally very low (<0.5 μg/L) indicating that there are only small inputs of metals from anthropogenic or natural sources. Some of the reticulation end points were found to have higher levels of metals such as Cu. This is likely due to the leaching of metals from metal pipes and fittings within the distribution system. The majority of samples were within WHO guidelines indicating that Viti Levu's water appears safe for drinking from a trace metal perspective. A relatively high value for As was found at one site which was located downstream of a gold mine tailings pond discharge.
对斐济群岛Viti Levu上几个主要水源和管网终点的饮用水样本进行了微量金属(As、Cd、Cr、Cu、Hg、Pb、Zn)含量分析。这项研究的目的是确定金属浓度是否在世界卫生组织(WHO)的指导方针范围内。利用各种原子吸收技术(火焰、石墨炉、氢化物生成)测定了金属的浓度。在源水中,微量金属的浓度普遍很低(<0.5 μg/L),表明只有少量的人为或自然来源的金属输入。一些网状末端被发现有较高水平的金属,如铜。这可能是由于配电系统内金属管道和配件的金属浸出所致。大多数样本符合世卫组织的指导方针,从微量金属的角度来看,Viti Levu的水似乎可以安全饮用。在某金矿尾矿库排放下游的一个地点发现了较高的砷含量。
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引用次数: 60
期刊
The South Pacific Journal of Natural and Applied Sciences
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