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Comparative & Combine HPLC Method of Development of Drugs and Validation of Cefixime & Ornidazole 头孢克肟、奥硝唑的对比联合高效液相色谱方法
Pub Date : 2018-07-05 DOI: 10.29070/15/57748
S. Sharma
Abstract – Cefixime is an oral third-generation cephalosporin antibiotic. It is used to treat gonorrhea, tonsillitis and pharyngitis. The chromatography of the present invention is used to determine Cefixime trihydrate and Ornidazole in bulk drugs and pharmaceutical dosage forms. Separation and quantification were achieved on ACEC 18, 5μm,150 x 4.6 mm i. d. column. The Cefixime trihydrate and Ornidazole were exposed to acidic, basic, oxidative, neutral, thermal, and photolytic stress conditions, and stress samples were analyzed. The linearity of the Cefixime trihydrate concentration in the range of 10 60 μg / mL was good, the correlation coefficient was 0.998, the Ornidazole correlation coefficient was 0.998, 25 150 μg / mL, and the correlation coefficient was 0.997. The intraday precision and accuracy of both analytes were less than 2% RSD.
头孢克肟是一种口服第三代头孢菌素类抗生素。用于治疗淋病、扁桃体炎和咽炎。本发明的色谱法用于测定原料药和制剂剂型中的三水合头孢克肟和奥硝唑。色谱柱为ACEC 18, 5μm,150 × 4.6 mm。将三水合头孢克肟和奥硝唑分别置于酸性、碱性、氧化性、中性、热和光解应激条件下,并对应激样品进行分析。三水合头孢克肟浓度在10 60 μg / mL范围内线性良好,相关系数为0.998;奥硝唑浓度在25 150 μg / mL范围内线性良好,相关系数为0.998;两种分析物的日内精密度和准确度均小于2% RSD。
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引用次数: 0
Migration of Youth from Villages in Uttarakhand 北阿坎德邦农村的青年移民
Pub Date : 2018-07-05 DOI: 10.29070/15/57716
A. Bharara
This paper will examine effects of migration on rural youths of Uttarakhand. The survey, study of migration commission report 2018on rural youths will tell the actual situation, a short review on the situation of youths. The economy is called “Money order economy” so the present economy review will also be including. The youths always play important role in every state. There are always many hindrances facing by rural youths i.e. poverty, unemployment, education etc. The state government is trying to improve situation of youths and there are some survey, data based on them. KeywordsYouth, Migration, Survey Study, Data report, Ghost Villages. X -
本文将研究移民对北阿坎德邦农村青年的影响。本次调查,研究移民委员会2018年关于农村青年的报告将讲述实际情况,对青年的情况进行简短的回顾。经济被称为“汇票经济”,所以现在的经济评论也将包括在内。年轻人在每个国家都扮演着重要的角色。农村青年总是面临着许多障碍,如贫困、失业、教育等。邦政府正在努力改善年轻人的状况,有一些基于他们的调查和数据。关键词:青年;人口流动;调查研究;X -
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引用次数: 0
चीनी यात्रियों द्वारा वर्णित भारतीय समाज : एक अध्ययन 中国游客描述的印度社会:一项研究
Pub Date : 2018-07-05 DOI: 10.29070/15/57747
Kritika Pareek
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引用次数: 0
Inveighing Against Inequity: Re-Reading Niranjan Mohanty’s Poetry of Protest 抨击不平等:重读尼兰詹·莫汉蒂的抗议诗歌
Pub Date : 2018-07-05 DOI: 10.29070/15/57729
S. Bose
Thomas Paine in the Rights of Man and Common Sense points out that every individual‟s duty is “to allow the same rights to others as we allow ourselves” and the failure to do so gives birth to social injustice. The Indian freedom fighters cherished the dream of a free India where equality and justice would reign supreme. India achieved freedom, but the dream of social equality and justice for all, still remains unrealized, be it women in particular or the common masses or nature. There is continuous exploitation every now and then. Niranjan Mohanty, the Orissan poet inveighs against such inequity prevalent in the society. This paper seeks to bring out and analyse the voice of protest in Mohanty‟s poems like Prayers to Lord Jagannatha, “Near the Temple”, “Kalahandi”, “The World”, “Taming”, “Bhubaneswar” etc. “Whatever is my right as a man is also the right of another; and it becomes my duty to guarantee as well as to possess.”
托马斯·潘恩在《人权与常识》一书中指出,每个人的责任是“允许别人享有我们自己所享有的同样的权利”,如果做不到这一点,就会产生社会不公正。印度的自由战士们怀着一个平等和正义至上的自由印度的梦想。印度实现了自由,但所有人的社会平等和正义的梦想仍然没有实现,特别是妇女、普通大众或大自然。不时有持续不断的剥削。奥里桑诗人尼兰詹·莫汉蒂猛烈抨击这种社会上普遍存在的不平等。本文试图揭示和分析莫汉蒂的诗歌中抗议的声音,如祈祷主贾甘纳塔,“寺庙附近”,“卡拉汉迪”,“世界”,“驯服”,“布巴内斯瓦尔”等。“作为一个人,我的权利也是他人的权利;我的责任不仅是占有,而且是保证。”
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引用次数: 0
Exploitation of Children in the Novels of Mulk Raj Anand 穆尔克·拉吉·阿南德小说中的儿童剥削
Pub Date : 2018-07-01 DOI: 10.29070/15/57429
Kumar Swasti Priye
Mulk Raj Anand was one of the triumvirates who inaugurated the new section of writers of fiction along with R. K. Narayan and Raja Rao. Anand is a novelist of urgent social concerns and preoccupations, and the social impulse is at the heart of his writing. He is considered the Messiah of the downtrodden, the unwanted and the unloved. Even in a random reading of Anand‘s novels, the reader becomes immediately aware of such issues as the tyranny of the caste system, its injustice, and its social, moral and economic consequences, class conflicts, exploitation of various kinds of the poor by the rich, quest for identity, search for freedom etc. Under colonial rule, a number of social and economic changes took place and as a result of feudal society was gradually into a capitalist one. The class system in India has turned out to be a new kind of caste system. It is built on the cash nexus on which it thrives. It has created a society much more complicated and devious and in some respects more rigid than the one created by caste. Therefore, it has become a very powerful device force, for more damaging to social cohesion than caste, as it had tended to segregate people into the rich and the poor, the haves and the haves-not. (The International Journal of Engineering and Science)
穆尔克·拉杰·阿南德是与r·k·纳拉扬和拉贾·拉奥一起开创小说作家新领域的三巨头之一。阿南德是一位关注紧迫的社会问题和当务之急的小说家,社会冲动是他作品的核心。他被认为是受压迫、不受欢迎和不受爱的人的弥赛亚。即使随便读一下阿南德的小说,读者也会立刻意识到诸如种姓制度的暴政、不公、社会、道德和经济后果、阶级冲突、富人对各种穷人的剥削、对身份的追求、对自由的追求等问题。在殖民统治下,社会经济发生了一些变化,封建社会逐渐转变为资本主义社会。印度的阶级制度变成了一种新的种姓制度。它是建立在现金联系的基础上的,而现金联系正是它蓬勃发展的基础。它创造了一个比种姓制度更复杂、更狡猾的社会,在某些方面也更僵化。因此,它已经成为一种非常强大的工具力量,比种姓制度对社会凝聚力的破坏更大,因为它倾向于将人们分为富人和穷人,富人和穷人。(国际工程与科学杂志)
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引用次数: 0
Rational Numbers 有理数
Pub Date : 2018-07-01 DOI: 10.29070/15/57856
J. .
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引用次数: 0
Hematological Changes Induced By 3G Mobile Phone Radiation in Male Wistar Rats 3G手机辐射对雄性Wistar大鼠血液学的影响
Pub Date : 2018-07-01 DOI: 10.29070/15/57557
R. Gautam, Neelu Singh, U. Singh
Mobile phones have become an integral part of everyone‟s life. Radiofrequency electromagnetic waves emitted from mobile phone interact with biological system and lead to increase in reactive oxygen species (ROS) which alters several biochemical processes. Therefore, to investigate the harmful effect of the radiations generated from 3G mobile phones, we analyzed the changes in hematological parameters of male Wistar rats. In present study, exposure of 3G mobile phone radiation was given to ten weeks old male Wistar rats (n=8) for 2 hours/day. The exposure was continued for duration of 45 days in specially designed exposure set up. On completion of exposure time period, hematological and immunological parameters of blood were performed. A significant change in WBC and lymphocytes counts was found. Therefore this may be concluded that mobile phone radiation effect the hematological parameters.
手机已经成为每个人生活中不可或缺的一部分。手机发射的射频电磁波与生物系统相互作用,导致活性氧(ROS)增加,从而改变多种生化过程。因此,为了研究3G手机辐射的有害影响,我们分析了雄性Wistar大鼠血液参数的变化。本研究以10周龄雄性Wistar大鼠(n=8)为研究对象,每天暴露于3G手机辐射2小时。在专门设计的暴露装置中持续暴露45天。暴露时间结束后,测定血液的血液学和免疫学指标。白细胞和淋巴细胞计数有明显变化。由此可以推断,手机辐射对血液学参数有影响。
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引用次数: 0
Poetic Concerns of Nissim Ezekiel and Keki Daruwalla: A Comparative Analysis 尼西姆·以西结与凯基·达鲁瓦拉诗歌关注的比较分析
Pub Date : 2018-07-01 DOI: 10.29070/15/57538
Rana Zaidi, Z. Hussain
Keki N. Daruwalla and Nissim Ezekiel are two powerful voices of modern Indian English Poetry. Their literary communication is testament to their poetic ability and singularity. Though Ezekiel and Daruwalla are among the current Indian English Poets, yet Ezekiel is senior to Daruwalla by almost two decades. Ezekiel began writing in the 1950s whereas Daruwalla in the 1970s. Hence, the work attempts to discover the matching bonds between the two poets in order to analyse the poetic cosmos of the two distinct time periods and in what manner these two poets, representatives of their age, are paving the way for the upcoming poets. In contrast to Ezekiel, Daruwalla is influenced by the western style of writing, more given to language and poetic form. Furthermore, in both the poets the personal and subjective experiences go a long way in shaping their poetic communication. In this background, this paper aims to highlight the various similarities and differences in the poetic themes of Nissim Ezekiel and Keki Daruwalla. It conclude that, both the poets highlighted social, cultural, traditional, superstitious, religious, mythical attitudes of the society recaptured the Socio-cultural aspects of Indian society in a realistic manner. They also highlighted various techniques and styles of writing poetry in Indian English literature.
Keki N. Daruwalla和Nissim Ezekiel是现代印度英语诗歌的两个强有力的声音。他们的文学交流证明了他们的诗歌才能和独特性。虽然Ezekiel和Daruwalla都是当今印度英语诗人,但Ezekiel比Daruwalla年长近20年。以西结在20世纪50年代开始写作,而达鲁瓦拉在70年代开始写作。因此,这部作品试图发现两位诗人之间的匹配关系,以分析两个不同时期的诗歌宇宙,以及这两位诗人,他们时代的代表,以何种方式为即将到来的诗人铺平道路。与以西结相反,达鲁瓦拉受到西方写作风格的影响,更注重语言和诗歌形式。此外,两位诗人的个人经历和主观经历对他们的诗歌交流有很大的影响。在此背景下,本文旨在突出尼西姆·以西结和凯奇·达鲁瓦拉在诗歌主题上的各种异同。文章的结论是,两位诗人都突出了社会、文化、传统、迷信、宗教和神话的态度,以现实的方式再现了印度社会的社会文化方面。他们还强调了印度英语文学中诗歌写作的各种技巧和风格。
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引用次数: 0
An Investigation on Liquid Chromatographic Technique for Simultaneous Measurement of Alprazolam and Mebeverine in Pharmaceutical Dose Form 液相色谱法同时测定药物剂型阿普唑仑和美贝弗林含量的研究
Pub Date : 2018-07-01 DOI: 10.29070/15/57490
Anup K Mamgain
A delicate, quick, exact and reproducible Isocratic, RP-LC strategy was created for assurance of Alprazolam and Mebeverine in pharmaceutical measurement frame. A Sunfire C18, 5 pm segment with portable stage containing methanol: cradle (0.02M KH2P04) (70:30). The stream rate was 1.0 ml/min and effluents were observed at 225 nm with help of PDA identifier. The maintenance time was 6.04 min. for ALP and 3.53 min. for MEB. The linearity was in the scope of 0.05-40 gg/ml for ALP and 0.2-40 pig/ml for MEB. The proposed strategy was approved regarding linearity, exactness, accuracy, specificity and strength. Because of straightforwardness, rate and exactness of technique, trust that the strategy will be helpful for routine quality control examination.
建立了一种灵敏、快速、准确、重现性好的等容反相液相色谱方法,以保证阿普唑仑和美贝弗林在药物测定框架中的含量。Sunfire C18,下午5点分段,带有携带甲醇的平台:支架(0.02M KH2P04)(70:30)。流速为1.0 ml/min,利用PDA识别器在225 nm处对流出物进行观察。ALP和MEB的维护时间分别为6.04 min和3.53 min。ALP的线性范围为0.05 ~ 40 gg/ml, MEB的线性范围为0.2 ~ 40猪/ml。该策略在线性度、精确性、准确度、特异性和强度方面均获得批准。由于该方法简单、快捷、准确,相信将有助于日常的质量控制检查。
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引用次数: 0
A Study of Crystal Growth, Basic Investigation, Characterization, Conformational Solidness and Quantum Substance Calculation of the Pharmaceutical Compound – P-Arsanilic Acid 药用化合物-对氨基苯甲酸晶体生长、基础研究、表征、构象固形性及量子物质计算研究
Pub Date : 2018-07-01 DOI: 10.29070/15/57489
Anup K Mamgain
P-Arsanilic acid, which is also called 4-amino phenyl arsonic acid, is a bioactive compound. Single crystals of p-Arsanilic acid (pAsA) are become effectively under moderate vanishing procedure. The crystallinity and parameters of the developed crystal are resolved with the powder x-beam diffraction result. The utilitarian gatherings are described by FTIR and FT-RAMAN spectra. The UV range uncovers its application in the optoelectronic field. The atomic structure of the title compound is examined utilizing Density utilitarian theory (DFT). The vibrational frequencies and the potential vitality conveyance (PED) are ascertained utilizing DFT/B3LYP 6-31+G** premise set. The dependability of the atom is controlled by different conformers in the computational strategy. The FIOMO-LUMO (Most noteworthy Involved Atomic Orbital Least Empty Sub-atomic Orbital) charge exchange and Non-Direct Optical (NLO) property assurance were done. The electrophilic and nucleophilic assault of the particle is contemplated utilizing the MEP (Atomic Electrostatic Potential). The hypothetical forecast of the thermodynamic properties helps in breaking down the future use of the title compound.
对胂酸,又称4-氨基苯基胂酸,是一种生物活性化合物。对氨基苯甲酸(pAsA)单晶在适度消失过程中得到了有效的生成。利用粉末x射线衍射结果对所制备晶体的结晶度和参数进行了解析。用傅里叶变换红外光谱和傅里叶变换拉曼光谱描述了功利聚集。紫外范围揭示了其在光电领域的应用。利用密度实用理论(DFT)研究了标题化合物的原子结构。利用DFT/ b3lyp6 -31+G**的前提集确定了振动频率和潜在活力传输(PED)。在计算策略中,原子的可靠性由不同的构象控制。进行了FIOMO-LUMO(最值得注意的涉及原子轨道最小空亚原子轨道)电荷交换和非直接光学(NLO)性质保证。粒子的亲电性和亲核性攻击是利用MEP(原子静电势)来考虑的。对热力学性质的假设预测有助于分解标题化合物的未来用途。
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引用次数: 0
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Journal of Advances and Scholarly Researches in Allied Education
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