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Predicting the Subjective Health Experience of Older Adults: A Modelling Approach. 预测老年人主观健康体验:一种建模方法。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-29 eCollection Date: 2025-01-01 DOI: 10.1155/jare/9997013
Damien S E Broekharst, Sjaak Bloem, Eline J Mertens, Nathascha Hanzen, Michel van Agthoven

Introduction: As people age, they increasingly face physical and cognitive decline, which can negatively affect their subjective health experience. To improve subjective health experience among older adults, it is crucial to understand its key predictors. Current literature points to frailty and vitality from geriatric research as well as acceptance and control from psychological science as key predictors. However, until now, they have never been incorporated in one composite model. Therefore, this study aims to develop, validate and differentiate a composite model integrating these predictors.

Methods: An online questionnaire covering sample characteristics and instruments on frailty, vitality, acceptance, control and subjective health experience was distributed among a sample of 753 older adults recruited from a research panel. Data were analysed using descriptive, reliability, validity and model statistics.

Results: Frailty shows modest to moderate negative relationships with acceptance, control and subjective health experience and a stronger negative relationship with vitality. Vitality relates moderately positively to control and subjective health experience and modestly to acceptance. Control has a strong positive relationship with acceptance and a modest one with subjective health experience. Acceptance shows a moderate positive relationship with subjective health experience. Frailty has a moderate significant negative indirect relationship with subjective health experience, through several modest but significant pathways involving vitality, acceptance and control combined or alone. Pathways with control alone are modest and nonsignificant. The models explain 41.5%-52.6% of the variance in subjective health experience.

Conclusion: It might be worthwhile to consider deploying the key concepts of the model, such as frailty, vitality, acceptance or control, as starting points for the development of future interventions concerning the subjective health experience of older adults. Such interventions may target frailty and promote vitality through tailored support, while aligning delivery with older adults' needs for control and acceptance.

随着人们年龄的增长,他们越来越多地面临身体和认知能力的下降,这可能会对他们的主观健康体验产生负面影响。为了改善老年人的主观健康体验,了解其关键预测因素至关重要。目前的文献指出,老年研究的脆弱和活力以及心理科学的接受和控制是关键的预测因素。然而,直到现在,它们还没有被合并到一个复合模型中。因此,本研究旨在开发、验证和区分整合这些预测因子的复合模型。方法:采用在线问卷调查的方法,对某研究小组中753名老年人进行问卷调查,问卷内容包括脆弱性、活力、接受度、控制力和主观健康体验等方面的样本特征和工具。采用描述性统计、信度统计、效度统计和模型统计对数据进行分析。结果:脆弱与接纳、控制和主观健康体验呈中等至中等负相关,与活力呈较强的负相关。活力与控制和主观健康体验适度正相关,与接受适度正相关。控制与接受有较强的正相关,与主观健康体验有较弱的正相关。接受度与主观健康体验呈中等正相关。脆弱与主观健康体验有中度显著的负向间接关系,通过几个适度但重要的途径,包括活力、接受和控制联合或单独。单独控制的通路是适度的和不显著的。这些模型解释了41.5%-52.6%的主观健康体验差异。结论:可能值得考虑部署模型的关键概念,如脆弱、活力、接受或控制,作为发展有关老年人主观健康体验的未来干预措施的起点。这些干预措施可以针对老年人的虚弱,通过量身定制的支持来促进活力,同时使服务与老年人的控制和接受需求保持一致。
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引用次数: 0
Thai Older Persons' Digital Capacity and Application of Technology for Healthy Aging: A Mixed-Method Study. 泰国老年人的数字能力和健康老龄化技术应用:一项混合方法研究。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-28 eCollection Date: 2025-01-01 DOI: 10.1155/jare/8080561
Thet Htoo Pan, Myo Nyein Aung, Saiyud Moolphate, Thin Nyein Nyein Aung, Yuka Koyanagi, Carol Ma Hok Ka, Eun Woo Nam, Jan A G M van Dijk, Motoyuki Yuasa

Background: Thailand has aged fast, becoming a superaging society. Simultaneously, ongoing rapid digital transformation puts older people at risk of being left behind. Research assessing the digital skills of older people and their application of digital technology for health is a literature gap.

Method: This study is an explanatory-sequential design mixed-method study. Community survey of 500 community older adults in Northern Thailand applied London School of Economics and Political Science (LSE) digital skills instrument to measure "operational internet skills," "information navigation skills," "social skills," "creative skills," and "mobile skills" and perceived health and technology use for health promotion. Quantitatively, Kruskal-Wallis and Mann-Whitney U tests identified differences in the digital skills across sociodemographic and internet use characteristics, while multivariable ordinal logistic regressions analyzed types of digital skills associated with health outcomes. Qualitatively, thematic analyses explained the quantitative findings in detail.

Results: The mean age of the participants was 68.36 years, of which 69% were female. Ordinal logistic regression identified that higher "social skills" positively influenced self-rated health (β = 0.32, 95% CI = 0.11-0.52), while 'Information navigation skills' affected internet use to access healthcare (β = 0.20, 95% CI = 0.04-0.36). Older adults with higher levels of 'operational skills' and 'social skills' positively associated with application of technology for health promotion in terms of improving eating habits ('operational skills', β = 0.54, 95% CI = 0.28-0.79; 'social skills', β = 0.64, 95% CI = 0.45-0.83); accessing healthcare ('operational skills,' β = 0.49, 95% CI = 0.23-0.75 'social skills' β = 0.74, 95% CI = 0.55-0.93) and accessing long-term care services ('operational internet skills,' β = 0.47, 95% CI = 0.21-0.73; 'social skills' β = 0.66, 95% CI = 0.47-0.85). Multiple focus-group interviews of older persons revealed how smart phone apps enabled them to stay connected, seek care and help others.

Conclusion: Therefore, it is urgent to enhance digital skills and internet use among older populations to promote healthy aging.

背景:泰国老龄化迅速,成为一个超老龄化社会。与此同时,正在进行的快速数字化转型使老年人面临被抛在后面的风险。评估老年人数字技能及其在健康方面应用数字技术的研究存在文献空白。方法:本研究采用解释-序列设计混合方法研究。对泰国北部500名社区老年人进行的社区调查采用了伦敦政治经济学院(LSE)的数字技能工具来衡量“操作互联网技能”、“信息导航技能”、“社交技能”、“创造技能”和“移动技能”,以及对健康和促进健康的技术使用的感知。在数量上,Kruskal-Wallis和Mann-Whitney U测试确定了数字技能在社会人口统计学和互联网使用特征方面的差异,而多变量有序逻辑回归分析了与健康结果相关的数字技能类型。在定性上,专题分析详细解释了定量结果。结果:参与者平均年龄68.36岁,其中女性占69%。有序逻辑回归发现,较高的“社交技能”对自评健康有积极影响(β = 0.32, 95% CI = 0.11-0.52),而“信息导航技能”影响互联网使用,以获得医疗服务(β = 0.20, 95% CI = 0.04-0.36)。在改善饮食习惯方面,“操作技能”和“社交技能”水平较高的老年人与健康促进技术的应用呈正相关(“操作技能”,β = 0.54, 95% CI = 0.28-0.79;“社交技能”,β = 0.64, 95% CI = 0.45-0.83);获得医疗保健(“操作技能”β = 0.49, 95% CI = 0.23-0.75“社交技能”β = 0.74, 95% CI = 0.55-0.93)和获得长期护理服务(“操作互联网技能”β = 0.47, 95% CI = 0.21-0.73;“社交技能”β = 0.66, 95% CI = 0.47-0.85)。对老年人进行的多次焦点小组访谈揭示了智能手机应用程序如何使他们保持联系、寻求护理和帮助他人。结论:提高老年人数字技能和互联网使用水平,促进健康老龄化迫在眉睫。
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引用次数: 0
Exploring the Psychosocial and Economic Challenges of Elders in Debre Tabor Metropolitan City: A Holistic Perspective. 探索德布雷塔博尔大都市老年人的社会心理和经济挑战:一个整体的视角。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-28 eCollection Date: 2025-01-01 DOI: 10.1155/jare/5665088
Haileeyesus Abera Gelaw

The rapid increase in the global aging population presents significant psychosocial and economic challenges, especially in underdeveloped nations. This study examines the experiences of elderly retired government employees (65+) in Debre Tabor Metropolitan City, Ethiopia, using a qualitative hermeneutical phenomenological approach. Structured interviews with 15 participants revealed key issues affecting their well-being. Findings show severe isolation and loneliness, with many feeling abandoned by their families and society. Emotional distress is common, with some expressing a desire for death due to neglect and a perceived loss of purpose. Financial instability worsens their hardships, as rising inflation and inadequate pensions make necessities unaffordable. Social marginalization and economic struggles lead to declining mental and physical health, increasing vulnerability. Elder abuse is a major concern, with many experiencing neglect, psychological distress, and a lack of respect from younger generations. Malnutrition further impacts their quality of life. The study emphasizes the need for stronger social support, policy reforms, and economic measures to protect elderly individuals. Recommendations include strengthening intergenerational relationships, revising pension policies, improving healthcare access, and implementing social programs to enhance community integration and support.

全球老龄化人口的快速增长带来了重大的社会心理和经济挑战,特别是在不发达国家。本研究采用定性解释学现象学方法,考察了埃塞俄比亚德布雷塔博尔市65岁以上的退休政府雇员的经历。对15名参与者的结构化访谈揭示了影响他们幸福感的关键问题。调查结果显示出严重的孤立和孤独,许多人感到被家庭和社会抛弃。情绪困扰很常见,有些人由于被忽视和感觉失去目标而表达了死亡的愿望。金融不稳定加剧了他们的困境,因为不断上升的通货膨胀和不足的养老金使他们负担不起必需品。社会边缘化和经济斗争导致身心健康下降,脆弱性增加。虐待老年人是一个主要问题,许多老年人受到忽视、心理困扰和缺乏年轻一代的尊重。营养不良进一步影响他们的生活质量。该研究强调需要加强社会支持、政策改革和经济措施来保护老年人。建议包括加强代际关系、修订养老金政策、改善医疗保健服务以及实施社会项目以加强社区融合和支持。
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引用次数: 0
Prevalence of Iron Deficiency Anaemia in Elderly Aged > 60 Taking Daily Low-Dose Aspirin. 每日服用低剂量阿司匹林的60岁老年人缺铁性贫血的患病率。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-28 eCollection Date: 2025-01-01 DOI: 10.1155/jare/6989003
Ali A Alaklabi, Abdulrahman S Altowaim, Hassan S Alqahtani, Abdulrahman A Bin Moammar, Abdulaziz T Alturki, Rakan A Al Muammar

Iron deficiency anaemia (IDA) and anaemia of chronic disease are both common causes of morbidity in the elderly population, where they increase hospitalization and mortality. The risk of IDA is increased in gastrointestinal bleeding caused by aspirin at low doses administered daily, which has been widely used to prevent cardiovascular diseases. The current research will compare the occurrence of IDA between patients under 81 mg of low-dose aspirin and nonaspirin users. The electronic medical records were reviewed for a retrospective cohort study in the King Abdulaziz Medical City, Riyadh, Saudi Arabia (2016-2023). The inclusion criteria were patients aged over 60 years who were taking 81 mg aspirin daily, and 1308 patients were included (654 aspirin users and 654 nonusers). The number of men using aspirin was 378 (56.5), and those not using it were 291 (43.5). The number of women using aspirin was 276 (43.2), and those not using it were 363 (56.8). In the IDA cases, there were 136 (20.8) and 165 (25.2) cases in aspirin and nonaspirin users, respectively. Although this was not a significant difference, the load of haemoglobin in aspirin users was markedly less with a high concentration of ferritin in the bloodstream than in nonusers. Hypertension was a risk factor for IDA. The IDA rates were higher in nonaspirin users in females, old patients and chronic steroid users. Aspirin and nonaspirin users did not differ significantly in terms of IDA incidence. Nonetheless, there were a decreased haemoglobin and an increased ferritin in aspirin users. Potential confounders may include age and BMI, which need to be considered when monitoring low-dose aspirin patients in old age.

缺铁性贫血(IDA)和慢性病贫血都是老年人发病的常见原因,它们增加了住院率和死亡率。阿司匹林已被广泛用于预防心血管疾病,但每日服用低剂量阿司匹林引起的胃肠道出血会增加IDA的风险。目前的研究将比较81毫克低剂量阿司匹林和非阿司匹林使用者之间IDA的发生率。在沙特阿拉伯利雅得的阿卜杜勒阿齐兹国王医疗城(2016-2023)进行了一项回顾性队列研究,对电子病历进行了审查。纳入标准为60岁以上、每日服用81毫克阿司匹林的患者,共纳入1308例患者(654例阿司匹林服用者和654例非服用者)。服用阿司匹林的男性为378人(56.5人),不服用阿司匹林的为291人(43.5人)。服用阿司匹林的女性人数为276人(43.2人),未服用阿司匹林的女性人数为363人(56.8人)。在IDA病例中,阿司匹林和非阿司匹林使用者分别有136例(20.8例)和165例(25.2例)。虽然这不是一个显著的差异,血红蛋白负荷的阿司匹林使用者明显少于在血液中高浓度的铁蛋白比非使用者。高血压是IDA的危险因素。女性非阿司匹林使用者、老年患者和慢性类固醇使用者的IDA发生率较高。阿司匹林和非阿司匹林使用者在IDA发生率方面没有显著差异。然而,阿司匹林服用者血红蛋白降低,铁蛋白升高。潜在的混杂因素可能包括年龄和体重指数,在监测老年低剂量阿司匹林患者时需要考虑这些因素。
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引用次数: 0
Barriers and Facilitators of Older Workers' Abilities to Obtain and Maintain Employment: A Scoping Review. 老年工人获得和维持就业能力的障碍和促进因素:范围审查。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-25 eCollection Date: 2025-01-01 DOI: 10.1155/jare/5609589
Jonathan Lai, Jacquie Eales, Matthew Lariviere, Jennifer Boger, Janet Fast

Throughout adulthood, the ability to access employment is vital for financial well-being, social inclusion and civic participation. This scoping review explores the factors that facilitate or challenge the abilities of workers age 50 and older to obtain and maintain paid employment. A total of 244 academic and grey literature articles were included in this scoping review. To frame the data extraction and analysis of included literature, we drew on Human Ecology Theory, a multidisciplinary theory that posits that individuals affect and are affected by the contexts they inhabit. Four key contexts were identified that impact older workers' employability (and the relevant codes that comprise each context): individual context (health, income and wealth accumulation, education and skills, employment history, lifestyle preferences and personal characteristics); family context (obligations with intimate partners, obligations to dependent children and caregiving obligations); workplace context (organizational characteristics, workplace policies, job characteristics and workplace relationships) and sociopolitical context (ageism, government labour and pension policies and macroeconomic conditions). We conclude that the employability of older workers is not attributable to a single factor within any of these contexts. Rather, older workers' abilities to maintain their labour force participation are fluid, situational and temporal, including aspects that arise across a person's life course as forms of cumulative advantage or disadvantage. Policies to support older workers' labour force participation require governments and employers to recognize how the dynamic lived experiences and relationships of individuals-within families, workplaces and society-shape their employability in later life.

在整个成年期,获得就业的能力对于经济福祉、社会包容和公民参与至关重要。本范围审查探讨了促进或挑战50岁及以上工人获得和维持有薪就业能力的因素。本综述共纳入244篇学术文献和灰色文献。为了对纳入的文献进行数据提取和分析,我们借鉴了人类生态学理论,这是一种多学科理论,假设个体影响并受其所处环境的影响。确定了影响老年工人就业能力的四种关键情况(以及构成每种情况的相关代码):个人情况(健康、收入和财富积累、教育和技能、就业经历、生活方式偏好和个人特征);家庭环境(与亲密伴侣的义务、对受抚养儿童的义务和照料义务);工作场所环境(组织特征、工作场所政策、工作特征和工作场所关系)和社会政治环境(年龄歧视、政府劳工和养老金政策以及宏观经济条件)。我们得出的结论是,老年工人的就业能力不能归因于任何这些背景下的单一因素。相反,老年工人维持其劳动力参与的能力是流动的、情境性的和暂时性的,包括在一个人的生命历程中作为累积优势或劣势形式出现的各个方面。支持老年工人参与劳动力的政策要求政府和雇主认识到个人在家庭、工作场所和社会中的动态生活经历和关系如何影响他们晚年的就业能力。
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引用次数: 0
From Vulnerability to Resilience: Roles of Community Support for Well-Being of Older Rohingya Refugees in Bangladesh. 从脆弱性到复原力:社区支持在孟加拉国老年罗兴亚难民福祉中的作用。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-24 eCollection Date: 2025-01-01 DOI: 10.1155/jare/4538913
Mohammed Mamun Rashid, Md Anamul Hoque, Sharmin Akter Joya

The Rohingya people have been subjected to egregious human rights abuses, culminating in a mass exodus to the Cox's Bazar district of Bangladesh in 2017. This study investigated the knowledge, attitudes, and practices surrounding older persons within the Rohingya refugee community while also elucidating the present community support mechanisms crucial for their well-being, through a sequential mixed-methods approach. The study specifically focuses on older Rohingya persons aged 60 years and above. A printed survey questionnaire was administered to 377 Rohingya refugees residing in camps, complemented by key informant interviews (KIIs) conducted with eight experts and community leaders to gain nuanced insights into the challenges and support systems. The quantitative data were analyzed using descriptive statistics to determine the prevalence of specific knowledges, attitudes, and practices while qualitative data from KIIs were subjected to thematic analysis in alignment with numerical facts, identifying recurring themes related to community support and vulnerabilities. The findings revealed that a significant majority (89.92%) of older Rohingya refugees lived within extended family structures, underscoring the importance of intergenerational coresidence, and a substantial proportion of respondents (87.23%) acknowledged and respected the wisdom and experience of elders. Family bonds, sociocultural, and religious factors played significant roles in ensuring personal care. However, older persons faced numerous vulnerabilities related to insufficient food, unfriendly infrastructure, inadequate healthcare, poor social services, and so on. This paper concludes with several recommendations particularly to strengthen community support for the well-being of older Rohingya refugees living in Bangladesh.

罗兴亚人遭受了严重的侵犯人权行为,最终导致2017年大批逃往孟加拉国的考克斯巴扎尔地区。本研究调查了罗兴亚难民社区中老年人的知识、态度和做法,同时也通过顺序混合方法阐明了目前对他们的福祉至关重要的社区支持机制。这项研究特别关注60岁及以上的罗兴亚老年人。我们向居住在难民营的377名罗兴亚难民发放了一份纸质调查问卷,并与8名专家和社区领袖进行了关键信息访谈(KIIs),以深入了解挑战和支持系统。定量数据使用描述性统计进行分析,以确定特定知识、态度和实践的流行程度,而来自kii的定性数据则根据数字事实进行专题分析,确定与社区支持和脆弱性相关的反复出现的主题。调查结果显示,绝大多数(89.92%)年长的罗兴亚难民生活在大家庭结构中,这凸显了代际共居的重要性,相当大比例的受访者(87.23%)承认并尊重老年人的智慧和经验。家庭纽带、社会文化和宗教因素在确保个人护理方面发挥了重要作用。然而,老年人面临着与粮食不足、基础设施不友好、医疗保健不足、社会服务差等有关的许多脆弱性。本文最后提出了几项建议,特别是加强社区对生活在孟加拉国的年长罗兴亚难民福祉的支持。
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引用次数: 0
Informal Caregiving in Pakistan: Role of Women Family Caregivers in Older People's Health. 巴基斯坦的非正式照顾:妇女家庭照顾者在老年人健康中的作用。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-04 eCollection Date: 2025-01-01 DOI: 10.1155/jare/2378593
Sumera Saeed Akhtar, Susan Heydon, Nadeem Irfan Bukhari

Introduction: This study explores the role of Pakistani women caregivers in older people's decision-making regarding access to healthcare services and medicine practices, including attitudes towards medicine adherence and self-medication.

Methods: Data were collected from 52 women who cared for older people using focus group discussions and semistructured interviews. The study was conducted in the rural and urban regions of Sargodha District, Punjab.

Results: Informal women caregivers play a pronounced role in decision-making about healthcare access and medicine-taking practices for older people. Treating illnesses at home with allopathic medicines is a common practice in both urban and rural settings. Caregivers were unaware of the risk associated with a delay in health-seeking and self-medication.

Conclusion: Findings suggest that educational interventions and coaching should be provided to improve family caregivers' knowledge so that they can contribute to better health outcomes for older people.

引言:本研究探讨了巴基斯坦妇女照顾者在老年人获得医疗保健服务和医学实践方面的决策中的作用,包括对药物依从性和自我药疗的态度。方法:采用焦点小组讨论和半结构化访谈的方法,对52名照顾老年人的妇女进行数据收集。这项研究是在旁遮普省萨戈达区的农村和城市地区进行的。结果:非正式女性护理人员在老年人获得医疗保健和服药实践的决策中发挥着显著的作用。在家里用对抗性药物治疗疾病在城市和农村都是一种常见的做法。护理人员没有意识到与延迟就医和自我用药相关的风险。结论:研究结果表明,应提供教育干预和辅导,以提高家庭照顾者的知识,使他们能够为老年人更好的健康结果做出贡献。
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引用次数: 0
The Experiences and Expectations of Older Adults and Close Family in Nursing Home and Emergency Department Transitions: A Qualitative Study. 老年人及其亲密家庭在疗养院和急诊科过渡中的经历和期望:一项定性研究。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.1155/jare/8896040
Elin Høyvik, Malcolm Bray Doupe, Gudmund Ågotnes, Frode Fadnes Jacobsen

Aim: To identify the experiences, expectations, and preferred transitional care expressed by nursing home residents and close family, thus mapping perceived barriers and facilitators to improve this identification process.

Design: In this study, a qualitative design was employed.

Methods: Individual, semistructured interviews were conducted.

Data sources: Interviews of 12 participants (3 residents and 9 close family) were conducted. The data were analyzed using thematic analysis to identify underlying themes.

Results: The following three themes were identified: (1) changes in life situations, (2) dimensions of transfer quality, and (3) interactions with staff.

Conclusion: Nursing home residents and close family emphasize that proper medical care is necessary. However, this is insufficient without addressing multiple ongoing life changes of individuals transitioning between nursing homes and emergency departments. Yet, this effort to manage life changes is significantly insufficient without the support of healthcare professionals.

目的:了解养老院居民及其亲密家庭对过渡性护理的体验、期望和偏好,从而绘制感知障碍和促进因素,以改善这一识别过程。设计:本研究采用定性设计。方法:采用个人半结构化访谈法。数据来源:对12名参与者(3名住院医师和9名近亲属)进行访谈。使用主题分析对数据进行分析,以确定潜在主题。结果:确定了以下三个主题:(1)生活情境的变化,(2)迁移质量的维度,以及(3)与员工的互动。结论:养老院居民和近亲属强调适当的医疗护理是必要的。然而,如果没有解决在养老院和急诊室之间过渡的个人的多种持续生活变化,这是不够的。然而,如果没有医疗保健专业人员的支持,这种管理生活变化的努力是远远不够的。
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引用次数: 0
Domain-Specific Physical Activity and Sedentary Behavior in Older Adults With Mobility Disability Risk Residing in a Continuing Care Retirement Community: A Cross-Sectional Study. 居住在持续护理退休社区中有行动障碍风险的老年人的特定领域身体活动和久坐行为:一项横断面研究。
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-10-13 eCollection Date: 2025-01-01 DOI: 10.1155/jare/7436862
Jemimah O Bakare, Soyoung Choi, Susan Aguiñaga, Ziyue Wang, Emerson Sebastião

Introduction: This study investigated domain-specific physical activity (PA) and sedentary behavior (SB) among older adults living in a Continuing Care Retirement Community (CCRC) as a function of risk of mobility disability.

Methods: Secondary cross-sectional data from 100 older CCRC residents were analyzed. The short physical performance battery (SPPB) assessed mobility disability risk, and PA and SB were self-reported. Data were analyzed using descriptive statistics, Mann-Whitney U test, and Quade's nonparametric ANOVA, with significance set at p < 0.05.

Results: Fifty-nine participants had an SPPB score < 10, indicating high mobility disability risk, while 41 had a score ≥ 10, indicating low risk. The low-risk group had higher total PA (67.1 ± 41.8 vs. 49.2 ± 40.5, p=0.012) and leisure PA (30.5 ± 25.1 vs. 21.2 ± 23.5, p=0.035) minutes, and higher total sedentary minutes (645.8 ± 209.6 vs. 567.0 ± 290.8, p=0.007) and non-screen sedentary minutes (447.1 ± 182.7 vs. 350.0 ± 164.8, p=0.002) than the high risk group. After controlling for age, perceived health, and assistive device use, the differences between groups were no longer significant (p > 0.05).

Discussion: Despite nonsignificant adjusted differences, our findings indicate overall low PA and high SB in the study participants. Given the well-documented benefits of PA, targeted interventions are needed to increase PA and reduce SB in this population.

摘要:本研究调查了生活在持续护理退休社区(CCRC)的老年人特定领域的身体活动(PA)和久坐行为(SB)对行动障碍风险的影响。方法:对100名老年CCRC居民的二次横断面资料进行分析。短物理性能电池(SPPB)评估行动障碍风险,PA和SB自报。数据分析采用描述性统计、Mann-Whitney U检验和Quade非参数方差分析,显著性设置为p < 0.05。结果:59例患者SPPB评分< 10分,为高活动障碍风险;41例患者SPPB评分≥10分,为低活动障碍风险。低风险组总PA(67.1±41.8比49.2±40.5,p=0.012)和休闲PA(30.5±25.1比21.2±23.5,p=0.035)分钟,总久坐时间(645.8±209.6比567.0±290.8,p=0.007)和非屏幕久坐时间(447.1±182.7比350.0±164.8,p=0.002)高于高风险组。在控制了年龄、感知健康和辅助器具使用后,组间差异不再显著(p < 0.05)。讨论:尽管调整后的差异不显著,但我们的研究结果表明,研究参与者的总体PA低,SB高。鉴于PA的益处有充分的证据,需要有针对性的干预措施来增加PA并降低这一人群的SB。
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引用次数: 0
Exercise Improves Cardiac Dysfunction in D-Galactose-Treated Rats by Regulation of IGF-1-Humanin Pathway. 运动通过调节IGF-1-Humanin通路改善d -半乳糖处理大鼠心功能障碍
IF 2.1 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2025-09-27 eCollection Date: 2025-01-01 DOI: 10.1155/jare/9949234
Hesam Askarimoghadam, Farzaneh Rostamzadeh, Maryamossadat Mirtajaddini Goki, Elham Jafari, Mahboobeh Yeganeh-Hajahmadi

Introduction: Humanin, a mitochondrial-derived peptide, decreases in the elderly. This study evaluated the effects of concurrent moderate-intensity endurance training (MIET) or high-intensity interval training (HIIT) with D-galactose injection on cardiac function, and the serum and heart levels of humanin and IGF-1 in Wistar male rats. Methods: Left ventricular systolic pressure (LVSP), left ventricular end diastolic pressure (LVEDP), ±maxdp/dt, contractility index (CI) and, Tau were monitored by PowerLab system in CTL, CTL + MIET, CTL + HIIT, D-gal, D-gal + MIET, and D-gal + HIIT groups. The histopathological score, fibrosis, and humanin and IGF-1 levels were measured with hematoxylin & eosin, Masson's trichrome, and enzyme-linked immunosorbent assay, respectively. Results: Histopathological score and heart fibrosis were reduced by HIIT and MIET in the D-gal group. LVSP, ±maxdp/dt, and CI were lower, while LVEDP and Tau were higher in the D-gal group than in the CTL group. MIET and HIIT alleviated the changes in LVSP, ±maxdp/dt, CI, LVEDP, and Tau. HIIT and MIET increased humanin levels in heart and serum of the D-gal group by modifying IGF-1 levels. Conclusion: The study suggests HIIT and MIET may improve cardiac function by regulating the IGF-1-humanin signaling pathway.

Humanin是一种线粒体衍生的肽,在老年人中减少。本研究评估了d -半乳糖注射同时进行中强度耐力训练(MIET)或高强度间歇训练(HIIT)对Wistar雄性大鼠心功能、血清和心脏中人素和IGF-1水平的影响。方法:采用PowerLab系统监测CTL、CTL + MIET、CTL + HIIT、D-gal、D-gal + MIET和D-gal + HIIT组左室收缩压(LVSP)、左室舒张末期压(LVEDP)、±maxdp/dt、收缩指数(CI)和Tau。采用苏木精&伊红法、马松三色法和酶联免疫吸附法分别测定组织病理学评分、纤维化、人素和IGF-1水平。结果:D-gal组HIIT组和MIET组心肌组织病理学评分和纤维化均降低。D-gal组LVSP、±maxdp/dt、CI低于CTL组,LVEDP、Tau高于CTL组。MIET和HIIT可减轻LVSP、±maxdp/dt、CI、LVEDP和Tau的变化。HIIT和MIET通过改变IGF-1水平增加了D-gal组心脏和血清中的人素水平。结论:HIIT和MIET可能通过调节IGF-1-humanin信号通路改善心功能。
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Journal of Aging Research
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