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The Underpinnings of Ageism: Multiple Mediational Model of Epistemological Style, Social Dominance Orientation, Right-Wing Authoritarianism, and Ageist Attitudes 年龄歧视的基础:认识论风格、社会支配取向、右翼威权主义和年龄歧视态度的多重中介模型
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-11-03 DOI: 10.1155/2019/3672725
Richard S. Henry, P. Perrin, Erin R Smith
This study seeks to understand the psychological factors that may contribute to the development and endorsement of ageist belief systems. Dual process theory is used to examine how one's worldview, beliefs in social hierarchy, authoritarian aggression, authoritarian submission, and conventionalism predict ageist attitudes. Participants living in the United States (n = 407) in 49 states and territories were recruited through this online national study and completed surveys of their ageist beliefs, epistemological style, social dominance orientation (SDO), and right-wing authoritarianism (RWA). RWA, SDO, and naïve realism were all positively associated with ageist beliefs. A hypothesized path model and two alternative models suggested the retention of a model whereby naïve realism led to RWA, which led to SDO, and finally to ageism. All possible direct and indirect effects were significant within the retained model, suggesting the presence of a multiple mediation. The fit of this model was superior to that of models testing alternative theoretical causal chains. Naïve realism may lead to authoritarian aggression, authoritarian submission, and conventionalism, which may then increase the value that people place on social hierarchies, and this may influence the development and retention of ageist beliefs. Helping people to understand what their basic beliefs about the world are and how they may play a role in the development of ageism may assist in reducing ageist attitudes.
本研究旨在了解可能导致年龄歧视信念系统发展和认可的心理因素。双重过程理论用于研究一个人的世界观、社会等级信仰、专制侵略、专制服从和传统主义如何预测年龄歧视态度。研究人员在美国49个州和地区招募了407名参与者,并对他们的年龄歧视信念、认识论风格、社会支配取向(SDO)和右翼威权主义(RWA)进行了调查。RWA、SDO和naïve现实主义都与年龄歧视信念呈正相关。假设路径模型和两个备选模型建议保留一个模型,其中naïve现实主义导致RWA, RWA导致SDO,最后导致年龄歧视。在保留的模型中,所有可能的直接和间接影响都是显著的,表明存在多重中介。该模型的拟合优于检验其他理论因果链的模型。Naïve现实主义可能导致专制侵略,专制服从和传统主义,这可能会增加人们对社会等级的重视,这可能会影响年龄歧视信仰的发展和保留。帮助人们了解他们对世界的基本信念是什么,以及他们如何在年龄歧视的发展中发挥作用,可能有助于减少对年龄歧视的态度。
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引用次数: 7
Exercise Snacking to Improve Muscle Function in Healthy Older Adults: A Pilot Study 运动零食改善健康老年人肌肉功能的初步研究
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-10-03 DOI: 10.1155/2019/7516939
Oliver J Perkin, Polly M. McGuigan, K. Stokes
Loss of muscle mass and strength are seemingly accepted as part of the ageing process, despite ultimately leading to the loss of independence. Resistance exercise is considered to be primary defence against loss of muscle function in older age, but it typically requires access to exercise equipment often in a gym environment. This pilot study aimed at examining the effect of a 28-day, unsupervised home-based exercise intervention on indices of leg strength and muscle size in healthy older adults. Twenty participants were randomly assigned to either maintain their habitual physical activity levels (Control; n=10; age, 74 (5) years; body mass, 26.3 (3.5) kg/m2) or undertake “exercise snacks” twice daily (ES; n=10; age, 70 (4) years; body mass, 25.0 (3.4) kg/m2). Both groups consumed 150 g of yogurt at their breakfast meal for the duration of the intervention. Sixty-second sit-to-stand score improved by 31% in ES, with no change in Control (p < 0.01). Large effect sizes were observed for the difference in change scores between the groups for interpolated maximum leg pressing power (6% increase in ES) and thigh muscle cross-sectional area (2% increase in ES). The present pilot data suggest that exercise snacking might be a promising strategy to improve leg muscle function and size in older adults and that further investigation into zero-cost exercise strategies that allow high frequency of training is warranted.
肌肉质量和力量的丧失似乎被认为是衰老过程的一部分,尽管最终会导致丧失独立性。阻力运动被认为是防止老年人肌肉功能丧失的主要防御措施,但它通常需要在健身房环境中使用锻炼设备。这项试点研究旨在检验28天、无监督的家庭锻炼干预对健康老年人腿部力量和肌肉大小指标的影响。20名参与者被随机分配为保持他们习惯性的体育活动水平(对照组;n=10;年龄,74(5)岁;体重,26.3(3.5) kg/m2)或每天吃两次“运动零食”(ES;n=10;年龄,70(4)岁;体重,25.0(3.4) kg/m2)。两组都消耗了150 在干预期间,在他们的早餐餐中摄入g酸奶。在ES中,第六十二次坐-站评分提高了31%,对照组没有变化(p<0.01)。在插值最大腿部压迫力(ES增加6%)和大腿肌肉横截面积(ES增加2%)方面,观察到两组之间变化评分的差异有很大的影响。目前的试点数据表明,运动零食可能是改善老年人腿部肌肉功能和体型的一种很有前途的策略,有必要进一步研究允许高频率训练的零成本运动策略。
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引用次数: 21
Twelve-Month Retention in and Impact of Enhance®Fitness on Older Adults in Hawai‘i Enhance®健身对夏威夷老年人12个月的保留和影响
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-09-02 DOI: 10.1155/2019/9836181
M. Tomioka, K. Braun, Y. Wu, K. Holt, Paula Keele, Lori Tsuhako, Johnny Yago
Introduction Enhance®Fitness is a low-cost group exercise program designed specifically for older adults (60+ years) to improve physical performance. The Hawai‘i Healthy Aging Partnership, a statewide health promotion initiative, has continuously offered Enhance®Fitness to Hawai‘i's multicultural population since 2007. This study examined 12-month participation in and impact of Enhance®Fitness on physical performance among older adults in Hawai‘i. Method Linear mixed-effects models were applied to analyze the physical performance measures (chair-stands, arm curls, and the up-and-go test) collected at baseline (month 0) and at 4, 8, and 12 months. We also compared the characteristics of participants who participated in the program for 12 months with those who dropped out in order to gain insights on participant retention. Results Of 1,202 older adults with baseline data, 427 (35.5%) were continuously enrolled in Enhance®Fitness for 12 months and participated in follow-up data collection. On average, participants attended 63.7% of thrice-weekly classes each month. Participants' physical performance measures improved after 4 months, continued to improve until 8 months, and were maintained thereafter. Besides continuous attendance, performance-measure improvements were associated with younger age, male gender, living with others (vs. alone), and fewer chronic conditions. Compared to those who completed 12 months of the program, the 775 who left the program over the course of the year were more likely to be younger, to be Caucasian (vs. Asian or Pacific Islander), to self-report depression as a chronic condition, and to have lower levels of fitness at baseline. Common reasons for dropping out were illness, relocation, time conflicts, lost interest, and transportation issues. Conclusions Long-term participants in Enhance®Fitness initially improved and then maintained physical performance. Future research is needed to identify strategies to maintain enrollment of older adults in the exercise programs over time.
Introduction Enhance®Fitness是一项低成本的团体锻炼计划,专门为60岁以上的老年人设计,旨在提高身体表现。夏威夷健康老龄化伙伴关系是一项全州范围的健康促进倡议,自2007年以来,该伙伴关系一直为夏威夷的多元文化人口提供Enhance®Fitness。这项研究调查了夏威夷老年人参加Enhance®Fitness 12个月的情况及其对身体表现的影响。方法应用线性混合效应模型分析在基线(0个月)和4、8和12个月收集的身体表现指标(椅子站立、手臂卷曲和向上运动测试) 月。我们还比较了参加该项目12年的参与者的特征 与那些为了深入了解参与者保留情况而退出的人相处了几个月。结果在1202名有基线数据的老年人中,427人(35.5%)连续参加Enhance®Fitness 12年 月,并参与了后续数据收集。平均而言,参与者每月参加63.7%的每周三次的课程。4天后,参与者的身体表现指标有所改善 月,持续改善至8 月,并在此后进行维护。除了持续出勤外,绩效指标的改善还与年龄较小、男性、与他人一起生活(与单独生活相比)以及慢性病较少有关。与完成12 在该项目的几个月里,在一年中离开该项目的775人更有可能更年轻,是高加索人(与亚洲或太平洋岛民相比),将抑郁症作为一种慢性疾病自我报告,并且在基线时的健康水平较低。辍学的常见原因有疾病、搬迁、时间冲突、失去兴趣和交通问题。结论Enhance®Fitness的长期参与者最初提高了体能,然后保持了体能。未来需要进行研究,以确定随着时间的推移保持老年人参与锻炼计划的策略。
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引用次数: 4
Study of the Immune Response in the Elderly: Is It Necessary to Develop a Vaccine against Neisseria meningitidis for the Aged? 老年人免疫应答的研究:是否有必要研制老年脑膜炎奈瑟菌疫苗?
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-08-22 DOI: 10.1155/2019/9287121
Gabriela Trzewikoswki de Lima, E. De Gaspari
Literature reports the association between aging and decline in the immune system function. The elderly have a higher risk of developing infectious diseases and are often less responsive to vaccines that are effective in the young. The case fatality rate of invasive meningococcal disease is higher in the elderly; therefore, vaccination for this population should be evaluated. Although new vaccines have been developed against Neisseria meningitidis, there is still a need to evaluate a vaccine for those older than 60 years, as the currently licensed vaccines are not indicated for this population.
文献报道了衰老和免疫系统功能下降之间的联系。老年人患传染病的风险较高,而且往往对对年轻人有效的疫苗反应较差。侵袭性脑膜炎球菌病在老年人中病死率较高;因此,应对这一人群的疫苗接种进行评估。尽管已经开发出针对脑膜炎奈瑟菌的新疫苗,但仍然需要评估针对60岁以上人群的疫苗,因为目前许可的疫苗并不适用于这一人群。
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引用次数: 9
Reliability of a Test for Assessment of Isometric Trunk Muscle Strength in Elderly Women 老年妇女躯干等长肌力测试评估的可靠性
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-07-01 DOI: 10.1155/2019/9061839
Marceli M A Mesquita, M. S. Santos, A. B. Vasconcelos, C. De Sá, Luana C D Pereira, Ínea B. M. da Silva-Santos, W. M. da Silva Júnior, D. G. de Matos, A. D. S. Fontes, P. Oliveira, F. Aidar, J. DeSantana, I. Fernandes, M. D. Da Silva-Grigoletto
Objective The aim of this study was to analyze the reproducibility of a protocol using the maximal isometric strength test of the trunk in elderly women aged above 60 years, without low back pain. Methods Twenty-one physically inactive elderly women, who had not engaged in any activity or exercise program in the past three months, participated in the cross-sectional study that consisted of two days of evaluations for the maximal isometric strength of the extensor and flexor muscles of the trunk, with a 48 h interval between the sessions. A platform with fixed seating was used, which allowed the fixation of the hip and lower limbs, with a load cell connected to a linear encoder. To verify the reliability of the test, the interclass correlation coefficient, variation coefficient, minimum detectable difference (MDD), standard error of measurement, and Bland–Altman graphs were calculated. Results No statistical difference was observed between the first and second evaluation, which indicates that there was no learning effect. Interclass correlation coefficient values were classified as very high and high for extensor (0.98) and flexor (0.86) muscles, respectively, besides low variation (9% for both muscle groups) and acceptable values for minimum detectable difference (extensors = 51.1 N, flexors = 48.9 N). In addition, the Bland–Altman analysis revealed low bias and values within the limits of agreement. Conclusion It is concluded that the test of maximum isometric strength of the trunk in healthy and trained elderly people presents high reliability. These values proved to be reliable if performed in at least two evaluation sessions, which confirms the hypothesis of the authors by the consistency of the measurement test.
目的本研究的目的是分析60岁以上无腰痛的老年妇女使用躯干最大等长强度测试方案的可重复性。方法21名在过去3个月内没有参加任何活动或锻炼计划的无运动的老年妇女参加了横断面研究,包括两天的躯干伸肌和屈肌的最大等长强度评估,每次评估间隔48小时。使用了一个带有固定座位的平台,可以固定髋关节和下肢,并将称重传感器连接到线性编码器。为了验证检验的信度,我们计算了类间相关系数、变异系数、最小可检测差异(MDD)、测量标准误差和Bland-Altman图。结果第一次评价与第二次评价无统计学差异,说明没有学习效果。伸肌(0.98)和屈肌(0.86)的类间相关系数值分别被分类为非常高和高,此外变化较小(两个肌群均为9%)和最小可检测差异的可接受值(伸肌= 51.1 N,屈肌= 48.9 N)。此外,Bland-Altman分析显示低偏差和在一致范围内的值。结论健康老年人躯干最大等距强度测试具有较高的可靠性。这些值被证明是可靠的,如果进行了至少两次评估会议,这证实了作者的假设,通过测量检验的一致性。
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引用次数: 6
Fall Risk Reduction Program Paired with a Transportation Program in an Underserved, Urban Minority Community: A Qualitative Evaluation 在服务不足的城市少数民族社区,降低跌倒风险计划与交通计划相结合:定性评估
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-07-01 DOI: 10.1155/2019/2719290
T. Mielenz, Laura L Durbin, Fern Hertzberg, Diana Noble-Hernandez, J. Sorensen
This study sought to evaluate A Matter of Balance/Volunteer Lay Leaders (AMOB/VLL) fall prevention curriculum in combination with a “door-through-door” program: Coordinated Older-Adult Senior Transportation Services (COASTS) for older adults living in an urban, underserved community. AMOB/VLL participants were offered eight 2-hour classes as part of the training program. Focus groups were conducted with older adult participants, COASTS mobility facilitators, and AMOB/VLL master trainers. A thematic analysis was conducted, and primary themes relating to curriculum content, cultural relevancy, and outcomes were examined. Older adults and facilitators felt the course was rewarding and led to improvements in mobility and confidence. Master trainers were more critical and recommended simplifying content, with tailored guidance for specific populations. They also recommended increased emphasis on balance and physical activity. Although participants and MoFas felt combining AMOB/VLL and COASTS was rewarding and improved participant mobility, master trainers and participants suggested minor modifications to increase program benefits for urban, underserved communities.
本研究旨在评估平衡问题/志愿者外行领袖(AMOB/VLL)预防跌倒课程与“门到门”项目相结合:为生活在城市,服务不足社区的老年人提供协调的老年人高级交通服务(coastal)。作为培训计划的一部分,AMOB/VLL参与者被提供了8个2小时的课程。焦点小组由老年人参与者、coastal mobility促进者和AMOB/VLL培训师组成。进行了主题分析,并检查了与课程内容,文化相关性和结果相关的主要主题。老年人和辅导员认为课程是有益的,并导致流动性和信心的改善。大师级培训师则更为挑剔,并建议简化内容,为特定人群提供量身定制的指导。他们还建议更加重视平衡和体育活动。尽管参与者和mofa认为将AMOB/VLL和coastal相结合是有益的,并改善了参与者的流动性,但培训师和参与者建议进行微小的修改,以增加城市服务不足社区的项目效益。
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引用次数: 1
Exploring the Perspectives of Older People on the Concept of Home 探讨老年人对家概念的看法
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-06-18 DOI: 10.1155/2019/2679680
D. Hatcher, E. Chang, V. Schmied, Sandra Garrido
Objectives Continuing to live at home is arguably one of the most important challenges older persons face as they age. The aim of this study was to clarify how older adults conceptualise home through age-related lifestyle changes. Methods Principles from grounded theory were used to examine the perspectives of 21 older adults obtained from three focus group discussions and 10 in-depth semistructured interviews. Results Four major categories were developed: “anchoring self,” “enabling freedom,” “being comfortable,” and “staying in touch.” Discussion. For the participants in this study remaining at home enabled a sense of independence and freedom, self-worth and identity, comfort, and an ongoing active role in the community. However, some aspects of home could be renegotiated despite changes to living location, with new social connections able to be forged and personal comforts being transferrable. This holds important implications for supporting older persons to both sustain living at home and to adjust to changing circumstances, suggesting the importance of drawing on the experiences of older persons themselves in developing strategies to promote successful aging.
目标继续在家生活可以说是老年人随着年龄的增长所面临的最重要挑战之一。这项研究的目的是阐明老年人如何通过与年龄相关的生活方式变化来概念化家庭。方法采用扎根理论原理,对21名老年人的观点进行调查,这些观点来自三次焦点小组讨论和10次深度半结构访谈。结果形成了四个主要类别:“锚定自我”、“实现自由”、“舒适”和“保持联系”。对于这项研究的参与者来说,留在家里可以让他们获得独立和自由感、自我价值和身份认同感、舒适感,以及在社区中持续发挥的积极作用。然而,尽管居住地点发生了变化,但家庭的某些方面可以重新谈判,可以建立新的社会联系,个人舒适可以转移。这对支持老年人维持在家生活和适应不断变化的环境具有重要意义,表明在制定促进成功老龄化的战略时借鉴老年人自身的经验的重要性。
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引用次数: 16
Examining the Association between Life-Space Mobility and Cognitive Function in Older Adults: A Systematic Review. 研究老年人生活空间流动性与认知功能之间的关系:一项系统综述。
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-06-02 eCollection Date: 2019-01-01 DOI: 10.1155/2019/3923574
Nileththi A De Silva, Michael A Gregory, Shree S Venkateshan, Chris P Verschoor, Ayse Kuspinar

Purpose: The purpose of this review is to investigate the relationship between life-space mobility and cognition in older adults.

Methods: MEDLINE, Embase, CINAHL, and PsycINFO were searched through December 2018 for studies containing measures of life-space mobility and cognitive function. Two independent reviewers screened studies. Eligible studies were combined using a random-effects model, and heterogeneity was assessed using the I 2.

Results: Thirty-five articles were identified for review. A moderate and statistically significant association (pooled r = 0.30, 95% confidence interval 0.19 to 0.40.) was observed between life-space mobility and cognition among nine studies. Life-space mobility demonstrated small-to-moderate associations with domain-specific cognitive functioning, particularly executive function, learning, memory, and processing speed. Furthermore, individuals who had restricted life-space mobility (Life-Space Assessment ≤ 40) experienced a steeper decline in cognition (β = 0.56 and p = 0.0471) compared to those who did not (Life-Space Assessment ≥ 41).

Conclusion: This review examined the association between life-space mobility and cognitive function in older adults. The results suggest that a moderate relationship between life-space mobility and cognition exists, whether adjusted or unadjusted for covariates such as sociodemographics, mental health, functional capacity, and comorbidities.

目的:探讨老年人生活空间活动能力与认知能力的关系。方法:检索MEDLINE、Embase、CINAHL和PsycINFO截至2018年12月包含生活空间流动性和认知功能测量的研究。两名独立评审员对研究进行了筛选。使用随机效应模型对符合条件的研究进行合并,并使用i2评估异质性。结果:35篇文章被纳入综述。9项研究中,生活空间流动性与认知之间存在中度且有统计学意义的相关性(合并r = 0.30, 95%可信区间0.19 ~ 0.40)。生活空间移动性与特定领域的认知功能,特别是执行功能、学习、记忆和处理速度有小到中等程度的关联。此外,生活空间流动性受限(life-space Assessment≤40)的个体认知能力下降幅度明显大于非生活空间流动性受限(life-space Assessment≥41)的个体(β = 0.56, p = 0.0471)。结论:本综述探讨了老年人生活空间活动能力与认知功能之间的关系。结果表明,生活空间流动性与认知之间存在适度的关系,无论是否调整了社会人口统计学、心理健康、功能能力和合并症等协变量。
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引用次数: 45
Rehabilitation for People Living with Dementia: A Scoping Review of Processes and Outcomes. 痴呆症患者的康复:过程和结果的范围审查。
IF 4.7 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-06-02 eCollection Date: 2019-01-01 DOI: 10.1155/2019/4141050
Maiken B Ravn, Kirsten S Petersen, Jette Thuesen

Objectives: The aim of this scoping review was to map intervention studies of rehabilitation for people living with dementia regarding processes and outcomes, with a particular focus on whether the intervention is person-centred, home-based, or organised adopting a multidisciplinary approach and measures outcomes relating to everyday functioning and well-being.

Methods: A systematic search of electronic databases was conducted in PubMed, CINAHL, PsycINFO, Embase, and Cochrane. Studies from 2005 to November 2018 were collected and screened for relevance and quality. Randomised control trials and prospective cohort trials reporting a statistically significant effect on one or more outcome measures were included. Included studies were mapped according to selected processes and outcome measures.

Results: Twenty-six intervention studies were included and mapped. Nineteen of the interventions were person-centred, nine were home-based, and 14 reported a multidisciplinary approach. Twelve of the interventions had activities of daily living as an outcome measure, and 14 had quality of life as an outcome measure.

Conclusion: Person-centredness appears in most rehabilitation interventions for people living with dementia. Other processes and outcomes are heterogeneously described in the research literature. Rehabilitation programmes can be home-based or take place at a centre. Although not exclusive, the organisation of rehabilitation can be multidisciplinary. Fewer than half of the intervention studies measure the impact on activities of daily living and quality of life. Future guidelines must take into account the weak evidence regarding these aspects.

目的:本综述的目的是绘制痴呆症患者康复的干预研究的过程和结果,特别关注干预是以人为中心的,以家庭为基础的,还是采用多学科方法组织的,并测量与日常功能和福祉相关的结果。方法:系统检索PubMed、CINAHL、PsycINFO、Embase、Cochrane等电子数据库。收集2005年至2018年11月的研究,并对其相关性和质量进行筛选。随机对照试验和前瞻性队列试验报告对一项或多项结果测量有统计学显著影响。纳入的研究是根据选定的过程和结果测量绘制的。结果:纳入并绘制了26项干预研究。其中19项干预措施以人为本,9项以家庭为基础,14项采用多学科方法。其中12项干预措施将日常生活活动作为结果衡量标准,14项干预措施将生活质量作为结果衡量标准。结论:以人为中心在大多数痴呆患者康复干预中出现。研究文献中对其他过程和结果的描述各不相同。康复方案可以以家庭为基础,也可以在中心进行。虽然不是排他性的,但康复的组织可以是多学科的。不到一半的干预研究测量了对日常生活活动和生活质量的影响。未来的指导方针必须考虑到这些方面的薄弱证据。
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引用次数: 12
Osteoarthritis, Exercise, and Tissue Engineering: A Stimulating Triad for Health Professionals. 骨关节炎、运动和组织工程:卫生专业人员的三重刺激。
IF 1.6 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2019-05-02 eCollection Date: 2019-01-01 DOI: 10.1155/2019/1935806
Pedro Morouço, Cristiana Fernandes, Rita Santos-Rocha

Osteoarthritis (OA) is a degenerative disease, promoted by abnormal chronic mechanical loading over the joint, for instance, due to excessive body mass. Patients frequently report pain, fatigue, and limitations in specific functional daily activities. Regarding the treatment of OA, two nonpharmacological options are available. However, it is not clear which type and intensity of exercise have better outcomes in treatment and how tissue engineering can be a promising field due to the mechanical load implants will suffer. The aims of this work were to investigate (1) the main characteristics, prevalence, and consequences of OA; (2) the exercise prescription guidelines and whether exercise interventions have a positive effect on OA treatment; and (3) the novel improvements on tissue engineering for OA treatment. Both patients and practitioners should be aware that benefits may come from prescribed and supervised exercise. Recent studies have highlighted that an optimal balance between exercise and nutritional income should be widely recommended. Regarding tissue engineering, significant steps towards the development of implants that mimic the native tissue have been taken. Thus, further studies should focus on the impact that exercise (repetitive loading) might have on cartilage regeneration. Finally, suggestions for future research were proposed.

骨关节炎(OA)是一种退行性疾病,是由于关节长期承受异常的机械负荷(如体重过大)而引起的。患者经常会感到疼痛、疲劳和日常功能活动受限。在治疗 OA 方面,有两种非药物疗法可供选择。然而,目前尚不清楚哪种类型和强度的运动能取得更好的治疗效果,也不清楚组织工程学如何能成为一个前景广阔的领域,因为植入物会承受机械负荷。这项工作的目的是调查:(1)OA 的主要特征、发病率和后果;(2)运动处方指南以及运动干预是否对治疗 OA 有积极作用;(3)组织工程对治疗 OA 的新改进。患者和医生都应意识到,处方和指导下的运动可能会带来益处。最近的研究强调,应广泛推荐运动与营养收入之间的最佳平衡。关于组织工程学,在开发模拟原生组织的植入物方面已经取得了重大进展。因此,进一步的研究应关注运动(重复负荷)对软骨再生可能产生的影响。最后,对未来的研究提出了建议。
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引用次数: 0
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Journal of Aging Research
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