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Biosecurity and Biodefense: Lessons from Ebola Virus Outbreak 生物安全和生物防御:埃博拉病毒爆发的教训
Pub Date : 2015-01-01 DOI: 10.4172/2157-2526.1000E112
P. Lebea
Copyright: 2014. Omics Publishing Group. This is an open-access article. Published in Journal of Bioterrorism & Biodefense, vol.2014, pp 2157-2526
版权:2014。Omics出版集团。这是一篇开放获取的文章。发表于《生物恐怖主义与生物防御杂志》2014年第2157-2526页
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引用次数: 3
Bioterrorism: an emerging global health threat. 生物恐怖主义:一个正在出现的全球健康威胁。
Pub Date : 2015-01-01 DOI: 10.4172/2157-2526.1000129
Syra S. Madad
The threat of bioterrorism has heightened over the past few years, given the history of asymmetric warfare. This threat posed by biological weapons is especially challenging, given the unique characteristics of these agents coupled with the dearth of knowledge in this particular subject by health care first responders. As the history of biowarfare has shown, exposure to even minute quantities of a biological agent can be fatal. As such, health care first responders will encounter the brunt of these cases. Therefore, it is imperative that health care first responders who provide emergency medical services be knowledgeable on the detection, diagnoses and response to biological agents so as to minimize adverse health effects and prevent fatalities. Information contained in this article includes overall awareness of select agents of bioterrorism and brief clinical characteristics of the most common and most likely bioterrorism agents known as Tier 1 select agents with the purpose of better preparing health care first responders in the event of a potential bioterrorism attack.
鉴于不对称战争的历史,生物恐怖主义的威胁在过去几年中有所加剧。鉴于生物武器的独特特性,加上卫生保健第一反应者在这一特定主题方面缺乏知识,生物武器构成的这一威胁尤其具有挑战性。生物战的历史表明,即使暴露在极少量的生物制剂中也可能是致命的。因此,卫生保健第一响应者将首当其冲地遇到这些病例。因此,提供紧急医疗服务的卫生保健第一反应者必须了解生物制剂的检测、诊断和反应,以尽量减少对健康的不利影响并防止死亡。本文中包含的信息包括对生物恐怖主义精选制剂的总体认识,以及最常见和最可能的生物恐怖主义制剂(称为一级精选制剂)的简要临床特征,目的是在潜在的生物恐怖主义袭击事件中更好地为卫生保健第一响应者做好准备。
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引用次数: 17
Problems of Clinical Diagnosis and Management of a Deliberate Biological Born Disease 先天性先天性疾病的临床诊断与治疗问题
Pub Date : 2015-01-01 DOI: 10.4172/2157-2526.1000E113
M. Balali-Mood, M. Moshiri
Mahdi Balali-Mood*1 and Mohammad Moshiri2,3 1Director, Medical Toxicology Research Centre, Mashhad University of Medical Sciences, Iran 2Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran 3Health insurance research office, Armed forces insurance organization of Islamic Republic of Iran, Tehran, Iran *Corresponding author: Mahdi Balali-Mood, Director, Medical Toxicology Research Centre, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences ,Mashhad , Iran; Tel: + 98-511-8819301, 98-9151157000; Fax:+ 98-511-8002467/8591057; E-mail: Mahdi.Balali-Mood@ncl.ac.uk
Mahdi Balali-Mood*1和Mohammad moshiri2,3伊朗马什哈德医科大学医学毒理学研究中心主任2伊朗马什哈德马什哈德医科大学药学院药理学与毒理学教研室3伊朗德黑兰伊朗伊斯兰共和国武装部队保险组织健康保险研究室*通讯作者:马什哈德医科大学医学院伊玛目礼萨医院医学毒理学研究中心主任Mahdi Balali-Mood,伊朗马什哈德;电话:+ 98-511-8819301,98-9151157000;传真:+ 98 - 511 8002467/8591057;电子邮件:Mahdi.Balali-Mood@ncl.ac.uk
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引用次数: 7
Journal of Bioterrorism and Biodefense: Past, Present and Future 生物恐怖主义和生物防御杂志:过去,现在和未来
Pub Date : 2015-01-01 DOI: 10.4172/2157-2526.1000E110
N. Burgis
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引用次数: 2
Children's Safety and Security 儿童安全与保障
Pub Date : 2015-01-01 DOI: 10.4172/2157-2526.1000E114
L. Massimo
We are currently facing a new problem in western countries, i.e., how to preserve the cultural and personal identity of immigrants and at the same time guarantee security to our inhabitants and citizens. This is a huge field involving both a broad number of different cultures and situations, and the additional difficulties which are caused by terrorism. Although cultural values are essential, it is extremely important to avoid ambiguity. While worldwide birth registration provides children with civil rights, including health care, social services, and education, security also increases thanks to personal identification [1-4]. Extreme poverty adds further risks. Education is one important aspect in preventing criminal acts and terrorism, because it is easier for criminal associations and terrorism to recruit people on the fringe of poverty and social isolation. In the currently existing melting pot, names lack constancy and reliability as a basis for identification.
在西方国家,我们正面临着一个新的问题,即如何保持移民的文化和个人身份,同时保证我们的居民和公民的安全。这是一个巨大的领域,既涉及大量不同的文化和情况,也涉及恐怖主义造成的额外困难。虽然文化价值是必不可少的,但避免歧义是极其重要的。在全世界范围内,出生登记为儿童提供了包括医疗保健、社会服务和教育在内的公民权利,同时,个人身份识别也增加了安全性[1-4]。极端贫困加剧了风险。教育是预防犯罪行为和恐怖主义的一个重要方面,因为犯罪组织和恐怖主义更容易招募处于贫困和社会孤立边缘的人。在目前存在的大熔炉中,名字缺乏作为识别基础的稳定性和可靠性。
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引用次数: 1
Emerging Infectious Disease and Bioterrorism 新发传染病和生物恐怖主义
Pub Date : 2015-01-01 DOI: 10.4172/2157-2526.1000E111
V. Wiwanitkit
The emerging infectious disease is the unwanted situation in public health. However, there are several new emerging infectious diseases within the past decade. The consideration on the worldwide outbreak of the new emerging infectious disease is set. An interesting point is the trend of bioterrorism using the new emerging infectious pathogen. This topic will be further discussed in this editorial.
新出现的传染病是公共卫生中不希望出现的情况。然而,在过去十年中出现了一些新的传染病。确定了对新出现的传染病在世界范围内爆发的考虑。有趣的一点是,利用新出现的传染性病原体进行生物恐怖主义的趋势。这篇社论将进一步讨论这个话题。
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引用次数: 2
Re-Emergence of Zaire Ebola Virus Disease: Lessons to be Learnt 扎伊尔埃博拉病毒病的再次出现:吸取的教训
Pub Date : 2014-10-02 DOI: 10.4172/2157-2526.1000e116
R. Dhaked
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引用次数: 0
Enhanced Syndromic Surveillance for the Fourth Japan-China-South Korea Trilateral Summit 2011 2011年第四届中日韩领导人会议强化综合征监测
Pub Date : 2013-12-30 DOI: 10.4172/2157-2526.1000126
Y. Sugishita, Y. Ohkusa, T. Sugawara, Naotaka Shimatani, Y. Nadaoka, Nobuyuki Kamiya, Y. Yasui, K. Taniguchi, N. Okabe
Background: When high profile events such as mass gatherings or political events are held, syndromic surveillances are enhanced to quickly detect health emergencies. Drawing on past experiences, enhanced surveillance was conducted during the Fourth Japan-China-South Korea Trilateral Summit (May 21-22, 2011). This report describes the details and results of the enhanced syndromic surveillance. Methods: Enhanced surveillance started on May 18, and ended on June 4, two weeks after the meeting, using three existing surveillance systems that operate routinely: Official Syndromic Surveillance, Ambulance Transfer Syndromic Surveillance, and Pharmacy Surveillance. The enhanced surveillance was a joint work between the Tokyo Metropolitan Government and the National Institute of Infectious Diseases. Information from the three surveillance systems was mutually exchanged and daily risk assessment on potential health emergencies such as bioterrorism and potential epidemics of infectious diseases was performed jointly. Results: During the enhanced surveillance period, the only case that required verification was one suspected measles case from the report in the Official Syndromic Surveillance. None of the cases in the Ambulance Transfer Syndromic Surveillance or the Pharmacy Surveillance required additional investigation. All three syndromic surveillance systems that were utilized for the enhanced surveillance are run routinely, and the enhancement areas were simply conducting the daily risk assessment and reporting. Therefore, the enhanced surveillance is conducted only by agreements and arrangements among members. In spite of very short notice, we were able to initiate the enhanced surveillance because the existing surveillance required no baseline or other preparation. The burden of implementation of surveillance was significantly small in comparison with the previous enhanced surveillance. Conclusions: It is possible to activate the enhanced surveillance arrangements whenever needed. We were able to make a comprehensive assessment by utilizing three syndromic surveillance systems, which we believe are useful in detecting a possible case of bioterrorism.
背景:在举行大规模集会或政治活动等高调活动时,应加强综合征监测,以迅速发现突发卫生事件。根据过去的经验,第四次中日韩三方峰会(2011年5月21日至22日)期间加强了监测。本报告描述了加强综合征监测的细节和结果。方法:加强监测于5月18日开始,并于会议两周后的6月4日结束,使用了三个常规运行的现有监测系统:官方综合征监测、救护车转移综合征监测和药房监测。加强监测是东京都政府和国立传染病研究所的一项联合工作。三个监测系统的信息相互交换,并对生物恐怖主义和传染病流行等潜在突发卫生事件进行了每日风险评估。结果:在加强监测期间,唯一需要核实的病例是官方综合征监测报告中的1例麻疹疑似病例。救护车转运综合征监测或药房监测中的病例均不需要进一步调查。用于加强监测的所有三个综合征监测系统都是常规运行的,加强地区只是进行日常风险评估和报告。因此,加强监督只能通过成员之间的协议和安排来进行。尽管通知时间很短,但我们能够启动加强的监测,因为现有的监测不需要基线或其他准备。与以前加强的监测相比,实施监测的负担要小得多。结论:在需要时可以启动加强的监测安排。我们利用三种症状监测系统进行了全面评估,我们认为这些系统对发现可能的生物恐怖主义案件很有用。
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引用次数: 8
Global Chemical, Biological, and Nuclear Threat Potential Prioritization Model 全球化学、生物和核威胁潜在优先排序模型
Pub Date : 2013-11-28 DOI: 10.4172/2157-2526.1000125
S. Caskey, B. Ezell, R. Dillon-Merrill
The Global Chemical, Biological, and Nuclear Threat Potential model is designed to provide a systematic and defensible technical prioritization of countries based the relative threat potential of each country. Threat potential is defined as the potential for a non-state actor (or terrorist organization) to exploit resources from within the country that support the development of a weapon of mass destruction or effect. This is accomplished by assessing the potential for successful acquisition of materials, expertise, and equipment, which are needed in the building of a weapon; and, the presence of a terrorist organization or organizations in the country aiming to develop such a weapon.
全球化学、生物和核威胁潜力模型旨在根据每个国家的相对威胁潜力,为各国提供系统和可防御的技术优先次序。威胁潜力被定义为非国家行为者(或恐怖组织)利用国内资源支持发展大规模毁灭性武器或效果的潜力。这是通过评估成功获得制造武器所需的材料、专门知识和设备的潜力来实现的;并且,该国存在一个或多个旨在开发这种武器的恐怖组织。
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引用次数: 4
Kala-Azar Policy and Programmes in Nepal: An Assessment 尼泊尔黑热病政策和规划:评估
Pub Date : 2013-07-18 DOI: 10.4172/2157-2526.1000124
S. Adhikari
Background: Kala-azar (KA; visceral leishmanasis) is a debilitating and devastating disease, which targets the poor. KA first emerged in Nepal in 1980 and Government of Nepal (GON) has acknowledged the disastrous effects of the disease on domestic economic growth and community development through the explicit identification of KA as a health problem. Objective: The paper has twofold objectives: to describe the policies and plans with regard to KA in Nepal and to assess their overall effectiveness. Methods: The assessment is primarily based on secondary information. The data were collected from various policies and plans, reports, records in government offices, and published and unpublished documents among others. Data collected from various sources were triangulated and analyzed to produce mid-term assessment of elimination KA. Assessment and conclusions: The existing KA policies and plans of the GON have rightly targeted the major areas of intervention of KA treatment, prevention and control – such as surveillance and early detection, provision of free drugs for KA treatment, demand side financing, insecticide sprays, health education and information among others. Outcomes of the intervention are improving, but in slow rate. Coordination among the KA affected countries is found rather weak. The existing policy is not sufficient to reduce the imported KA cases.
背景:黑热病(KA;内脏利什曼病(内脏利什曼病)是一种使人衰弱和毁灭性的疾病,主要针对穷人。KA于1980年首次在尼泊尔出现,尼泊尔政府承认该病对国内经济增长和社区发展的灾难性影响,明确将KA确定为一个健康问题。目的:本文有两个目标:描述尼泊尔关于KA的政策和计划,并评估其总体有效性。方法:采用二级资料为主的评价方法。这些数据是从各种政策和计划、报告、政府办公室的记录、公开和未公开的文件等中收集的。对从各种来源收集的数据进行三角测量和分析,以产生消除KA的中期评估。评估和结论:尼泊尔政府现有的KA政策和计划正确地针对KA治疗、预防和控制的主要干预领域,如监测和早期发现、为KA治疗提供免费药物、需求方融资、杀虫剂喷雾、健康教育和信息等。干预的结果正在改善,但速度缓慢。受KA影响的国家之间的协调相当薄弱。现行政策不足以减少输入性KA病例。
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引用次数: 3
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Journal of Bioterrorism and Biodefense
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