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Journal of Craniofacial Surgery最新文献

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Review of "Synthetic Data Generated By Artificial Intelligence to Optimize Surgical Trial Design" by Foppa et al. Annals of Surgery 2025;282:810-817. Foppa等人的“人工智能合成数据优化手术试验设计”综述。外科年鉴2025;282:810-817。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-30 DOI: 10.1097/SCS.0000000000012421
Julian J Gonzales, Larry H Hollier
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引用次数: 0
Computer-Guided Biopsy of Osteosclerotic Jaw Lesion Using 3D-Printed Surgical Guides: A Fully Digital Workflow. 使用3d打印手术指南的骨硬化性颌骨病变的计算机引导活检:一个完全数字化的工作流程。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-30 DOI: 10.1097/SCS.0000000000012501
Pierluigi Mariani, Diana Russo, Francesco Rullo, Lucio Lo Russo, Angelo Salamini, Vincenzo Ronsivalle, Marco Cicciù, Luigi Laino

Osteosclerotic jaw lesions, often incidentally detected on routine radiographs, are rarely biopsied due to their benign appearance and proximity to delicate anatomic structures. This case report presents a fully digital workflow for guided biopsy of a deep mandibular osteosclerotic lesion, integrating artificial intelligence-based segmentation, intraoral scanning, CAD design, and 3D printing of surgical templates. A 3D-printed guide with depth-control stops was used to safely and precisely position trephine burs between the roots of tooth 4.6 and the mandibular canal. The approach allowed accurate tissue sampling for histopathologic diagnosis (osteoma), minimizing invasiveness and risk to adjacent structures. Postoperative CBCT confirmed the accuracy of the biopsy, with deviations of 0.6 mm (linear), 4 degrees (angular), and -0.2 mm (depth). This technique demonstrates the potential of artificial intellingence-assisted digital planning and 3D printing to enhance biopsy precision for intraosseous lesions.

骨硬化性颌骨病变通常在常规x线片上偶然发现,由于其良性外观和靠近脆弱的解剖结构,很少进行活检。本病例报告介绍了一个完全数字化的下颌骨深部骨硬化病变活检流程,整合了基于人工智能的分割、口内扫描、CAD设计和手术模板的3D打印。使用3d打印的深度控制支架安全精确地定位4.6牙根和下颌管之间的环钻刺。该方法允许对组织病理诊断(骨瘤)进行准确的组织采样,最大限度地减少对邻近结构的侵袭和风险。术后CBCT证实了活检的准确性,偏差为0.6 mm(线性),4度(角度)和-0.2 mm(深度)。这项技术展示了人工智能辅助数字规划和3D打印在提高骨内病变活检精度方面的潜力。
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引用次数: 0
Evaluation of Maxillary Stability in Simultaneous Downward Repositioning and Expansion With Miniplates, Screws, and Allograft. 微型钢板、螺钉和同种异体移植物同时向下定位和扩张上颌稳定性的评价。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-30 DOI: 10.1097/SCS.0000000000012490
Gustavo M Albuquerque, José Vinicius Bolognesi Maciel, Sara E Munkwitz, Hana Shah, Nicholas J Iglesias, Vasudev Vivekanand Nayak, Seth R Thaller, Paulo G Coelho, Joao L Carlini

Maxillary expansion and downward repositioning are among the least stable movements in orthognathic surgery. However, they are often necessary for functional and aesthetic purposes. Although combining these movements can reduce the need for multiple surgical procedures, it increases the risk of instability and requires stabilization techniques to prevent relapse. A multitude of approaches have been described, yet the literature remains limited in optimal strategies to enhance long-term outcomes. This retrospective study evaluated patients who underwent simultaneous maxillary expansion and downward repositioning using segmental Le Fort I osteotomy over a 24-month follow-up period. All patients underwent orthodontic preparation, followed by miniplate stabilization and interpositional bone grafting with tibial allogenic blocks. Data collected included surgical movements performed, dental cast measurements, postoperative imaging, and clinical assessment. Overall, 23 patients (mean age: 41.1±10.3 years) were included. All patients underwent maxillary advancement (3-9 mm) with inferior repositioning (2-9 mm), while 19 patients (82.6%) had concomitant mandibular procedures. Intercanine widths increased from 24.0±2.2 mm to 27.5±2.1 mm ( p <0.001), while intermolar widths increased from 33.0±0.6 mm to 38.7±0.7 mm ( p <0.001). Over 24 months, no complications were reported, including dehiscence, graft exposure, gingival recession, root injury, or relapse. Aesthetic improvement was evident in exposure of the incisors, and radiographs confirmed stable bone healing. When using current surgical methods and interdisciplinary coordination, this technique can be executed as a single-stage procedure with safety and reliability, minimizing patient morbidity and eliminating the need for additional interventions.

上颌扩张和向下复位是正颌手术中最不稳定的动作。然而,它们通常是功能和美学目的所必需的。虽然结合这些运动可以减少多次手术的需要,但它增加了不稳定的风险,需要稳定技术来防止复发。已经描述了多种方法,但文献仍然局限于提高长期结果的最佳策略。本回顾性研究评估了在24个月的随访期间,采用节段性Le Fort I截骨术同时进行上颌扩张和向下复位的患者。所有患者均进行了正畸准备,随后进行了微型钢板稳定和胫骨同种异体块间位植骨。收集的数据包括手术动作、牙模测量、术后影像和临床评估。总共纳入23例患者(平均年龄:41.1±10.3岁)。所有患者均行上颌前移(3- 9mm)和下颌骨复位(2- 9mm)手术,19例患者(82.6%)同时行下颌骨手术。齿间宽度从24.0±2.2 mm增加到27.5±2.1 mm (p
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引用次数: 0
A Decade of Craniosynostosis Surgery in the United States: Trends in Management, Payer Mix, and Cost. 美国颅缝闭锁手术的十年:管理、付款人组合和费用的趋势。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-30 DOI: 10.1097/SCS.0000000000012496
Andrew Salib, Victoria Kong, Jake Moscarelli, Omar Allam, Emily Parker, Nikita Singh, Gabriela Hernández-Busot, Michael Alperovich

Background: Cranial vault remodeling (CVR) and endoscopic strip craniectomy (SC) are principal operations for nonsyndromic craniosynostosis. Over the past decade, evolving minimally invasive techniques and shifting payer landscapes may have influenced national practice patterns. We evaluated trends in surgical utilization, payer mix, and cost across US children's hospitals from 2016 to 2025.

Methods: A retrospective analysis of the Pediatric Health Information System identified infants with craniosynostosis who underwent CVR or SC between 2016 and 2025 using ICD and CPT codes. Demographics, payer type, and inflation-adjusted cost were compared. Annual trends in utilization, payer mix, and cost were analyzed with linear regression.

Results: Among 15,335 infants, 13,329 underwent CVR and 2006 SC. Strip craniectomy patients were younger (95 versus 280 d, P<0.001), more often male (70.8% versus 64.7%, P<0.001), from higher-income households (median $46,124 versus $42,374, P<0.001), and had a higher proportion of privately insured patients (62.1% versus 47.4%, P<0.001) and a lower proportion of Black children (3.1% versus 8.4%, P<0.001). Strip craniectomy use increased from 8.8% to 20.2% of procedures (β=1.23%/yr, P<0.001). Strip craniectomy cost rose from $14,990 to $21,660 (+$632/yr, P=0.002). Medicaid coverage increased among SC patients (27.0%-39.6%, β= +1.27%/yr, P<0.001) but decreased among CVR patients (48.6%-45.8%, β= -0.40%/yr, P=0.038).

Conclusions: From 2016 to 2025, craniosynostosis care shifted toward increased use of minimally invasive strip craniectomy, accompanied by rising SC costs and greater Medicaid representation. Despite these changes, sociodemographic disparities in access to early, minimally invasive repair persist. These findings provide national benchmarks for utilization, payer patterns, and cost to guide clinical practice and policy.

背景:颅拱顶重塑(CVR)和内窥镜条形颅骨切除术(SC)是治疗非综合征性颅缝闭闭的主要手术。在过去的十年中,不断发展的微创技术和不断变化的付款人格局可能影响了国家的实践模式。我们评估了2016年至2025年美国儿童医院手术使用、付款人组合和成本的趋势。方法:对儿童健康信息系统进行回顾性分析,确定2016年至2025年间使用ICD和CPT代码进行CVR或SC的颅缝闭闭婴儿。比较了人口统计、付款人类型和通货膨胀调整后的成本。利用线性回归分析了年度使用率、支付者组合和费用的趋势。结果:在15335名婴儿中,13329名接受了CVR和2006例SC。条形颅骨切除术的患者年龄较小(95天和280天)。结论:从2016年到2025年,颅缝闭合的治疗转向增加微创条形颅骨切除术的使用,伴随着SC成本的上升和医疗补助的增加。尽管有这些变化,但在获得早期微创修复方面的社会人口差异仍然存在。这些发现为指导临床实践和政策的使用、付款人模式和成本提供了国家基准。
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引用次数: 0
Choanal Polyp Originating From Uncinate Process of Nasal Cavity. 起源于鼻腔钩突的后肛门息肉。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-30 DOI: 10.1097/SCS.0000000000012479
Sang Hoo Park, Soohyun Sim, Soo Jin Jeong, Seong Kook Park

Choanal polyps are benign solitary soft tissue lesions which originates from the nasal or paranasal sinus mucosa and progress through the natural ostium of the sinus to choana into the nasopharynx. Antrochoanal polyps are most common type. Nasal septum, sphenoid sinus, ethmoid sinus, inferior and middle turbinate, inferior and middle meatus have been reported as ectopic origin of choanal polyp as well. However, choanal polyps originating from uncinate process of nasal cavity has not been reported. Herein, with a review of the literature, we report a rare case of choanal polyps originating from uncinated process of nasal cavity in a 52-year-old woman.

后鼻孔息肉是一种良性的孤立性软组织病变,起源于鼻窦或副鼻窦粘膜,并通过鼻窦的自然口发展到后鼻孔进入鼻咽部。鼻后鼻息肉是最常见的类型。鼻中隔,蝶窦,筛窦,下鼻甲和中鼻甲,下鼻甲和中鼻甲也被报道为后肛门息肉的异位起源。然而,起源于鼻腔钩突的后肛门息肉尚未见报道。在此,我们回顾文献,我们报告一个罕见的病例后肛门息肉起源于无突起的鼻腔,在52岁的妇女。
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引用次数: 0
Safety and Operative Outcomes of the Use of Resorbable Distractors in Posterior Cranial Vault and Mandibular Distraction. 可吸收牵张器用于后颅穹窿和下颌牵张的安全性和手术效果。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-29 DOI: 10.1097/SCS.0000000000012475
Rawan ElAbd, Nabil Amraoui, Raina Patel, Asli Pekcan, Laura Herrera Gomez, Dino Zammit, Jeffrey Hammoudeh, Mark Urata

Background: Distraction osteogenesis (DO) is a critical craniofacial technique used to address congenital and acquired skeletal deficiencies through gradual bone elongation. While metallic devices have been traditionally employed for both mandibular distraction (MD) and posterior cranial vault distraction (PCVD), resorbable distractors offer several advantages, including elimination of secondary hardware removal procedures and decreased risk of dural violation. This systematic review evaluates the safety, technical feasibility, and operative outcomes of resorbable distractors in PCVD and MD.

Methods: A comprehensive literature search was conducted according to PRISMA guidelines across PubMed, Cochrane, EMBASE, and ClinicalTrials.gov through April 2024. Studies evaluating resorbable distractor systems in PCVD or MD were included. Data were extracted on operative characteristics, complications, clinical outcomes, and comparisons to metallic controls.

Results: Thirteen studies encompassing 205 patients (5 PCVD, 8 MD) were included. Hybrid systems combining metallic distraction arms with resorbable fixation were common in PCVD, while most MD procedures employed fully resorbable distractors. In PCVD, latency periods ranged from 2 to 5 days, distraction periods from 23 to 48 days, and consolidation durations averaged 3 to 4 months. Mean distraction rate was ~1 mm/d. All patients achieved clinical improvement, with one study reporting a 15.8% intracranial volume increase. Complication rates were low, with only one patient requiring revision surgery. In MD, distraction periods ranged from 10 to 30 days with consolidation times of 4 to 7 weeks. Mean lengthening ranged from 7 to 25.4 mm. Across studies, 100% clinical success was reported in nearly all cohorts, except for 2 patients with persistent airway obstruction. Complications included infections, device displacement, and regression; however, the use of resorbable plates was associated with significantly reduced postoperative regression (5.1% versus 32.9% in controls). Device absorption time ranged from 6 to 12 months.

Conclusions: Resorbable distractor systems in both PCVD and MD demonstrate excellent safety profiles and favorable functional and aesthetic outcomes. These systems offer meaningful operative advantages, including reduced surgical morbidity, fewer revisions, and avoidance of secondary procedures, making them a valuable alternative to metallic hardware in select pediatric craniofacial populations.

背景:牵张成骨术(DO)是一项重要的颅面技术,用于通过逐渐的骨伸长来解决先天性和后天性骨骼缺陷。虽然金属装置传统上用于下颌牵张(MD)和后颅拱顶牵张(PCVD),但可吸收牵张器具有几个优点,包括消除二次硬体移除手术和降低硬脑膜侵犯的风险。本系统综述评估了可吸收性牵张器在PCVD和md中的安全性、技术可行性和手术结果。方法:根据PRISMA指南在PubMed、Cochrane、EMBASE和ClinicalTrials.gov上进行了全面的文献检索,截止到2024年4月。包括评估可吸收牵张器系统在PCVD或MD中的应用的研究。提取手术特征、并发症、临床结果以及与金属对照的比较数据。结果:纳入了13项研究,包括205例患者(5例PCVD, 8例MD)。金属牵张臂与可吸收固定相结合的混合系统在PCVD中很常见,而大多数MD手术采用完全可吸收牵张器。PCVD的潜伏期为2 ~ 5天,分散期为23 ~ 48天,实变期平均为3 ~ 4个月。平均牵张率~1 mm/d。所有患者均获得临床改善,其中一项研究报告颅内容积增加15.8%。并发症发生率低,只有1例患者需要翻修手术。在MD中,分散期为10 - 30天,巩固期为4 - 7周。平均长度为7 ~ 25.4 mm。在所有研究中,除了2例持续性气道阻塞患者外,几乎所有队列的临床成功率均为100%。并发症包括感染、器械移位和复位;然而,可吸收钢板的使用显著降低了术后退化(5.1%对32.9%的对照组)。器件吸收时间为6至12个月。结论:可吸收牵张器系统在PCVD和MD中表现出良好的安全性和良好的功能和美观效果。这些系统提供了有意义的手术优势,包括降低手术发病率,更少的翻修,避免二次手术,使其成为有价值的替代金属硬件在儿童颅面人群。
{"title":"Safety and Operative Outcomes of the Use of Resorbable Distractors in Posterior Cranial Vault and Mandibular Distraction.","authors":"Rawan ElAbd, Nabil Amraoui, Raina Patel, Asli Pekcan, Laura Herrera Gomez, Dino Zammit, Jeffrey Hammoudeh, Mark Urata","doi":"10.1097/SCS.0000000000012475","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012475","url":null,"abstract":"<p><strong>Background: </strong>Distraction osteogenesis (DO) is a critical craniofacial technique used to address congenital and acquired skeletal deficiencies through gradual bone elongation. While metallic devices have been traditionally employed for both mandibular distraction (MD) and posterior cranial vault distraction (PCVD), resorbable distractors offer several advantages, including elimination of secondary hardware removal procedures and decreased risk of dural violation. This systematic review evaluates the safety, technical feasibility, and operative outcomes of resorbable distractors in PCVD and MD.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted according to PRISMA guidelines across PubMed, Cochrane, EMBASE, and ClinicalTrials.gov through April 2024. Studies evaluating resorbable distractor systems in PCVD or MD were included. Data were extracted on operative characteristics, complications, clinical outcomes, and comparisons to metallic controls.</p><p><strong>Results: </strong>Thirteen studies encompassing 205 patients (5 PCVD, 8 MD) were included. Hybrid systems combining metallic distraction arms with resorbable fixation were common in PCVD, while most MD procedures employed fully resorbable distractors. In PCVD, latency periods ranged from 2 to 5 days, distraction periods from 23 to 48 days, and consolidation durations averaged 3 to 4 months. Mean distraction rate was ~1 mm/d. All patients achieved clinical improvement, with one study reporting a 15.8% intracranial volume increase. Complication rates were low, with only one patient requiring revision surgery. In MD, distraction periods ranged from 10 to 30 days with consolidation times of 4 to 7 weeks. Mean lengthening ranged from 7 to 25.4 mm. Across studies, 100% clinical success was reported in nearly all cohorts, except for 2 patients with persistent airway obstruction. Complications included infections, device displacement, and regression; however, the use of resorbable plates was associated with significantly reduced postoperative regression (5.1% versus 32.9% in controls). Device absorption time ranged from 6 to 12 months.</p><p><strong>Conclusions: </strong>Resorbable distractor systems in both PCVD and MD demonstrate excellent safety profiles and favorable functional and aesthetic outcomes. These systems offer meaningful operative advantages, including reduced surgical morbidity, fewer revisions, and avoidance of secondary procedures, making them a valuable alternative to metallic hardware in select pediatric craniofacial populations.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146085908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Factors and Reoperation Strategies in Microvascular Decompression for Hemifacial Spasm. 面肌痉挛微血管减压的复发因素及再手术策略。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-29 DOI: 10.1097/SCS.0000000000012502
Xie Xiangtong, Zhou Shijun, Hanchun Chen, Dongyi Jiang, Yang Debao

Objective: To investigate the factors contributing to the recurrence of hemifacial spasm after microvascular decompression (MVD) and the outcomes of reoperation with MVD.

Methods: The authors retrospectively collected clinical data from 24 patients with recurrent hemifacial spasm after MVD treated at the Department of Neurosurgery, Suzhou Kowloon Hospital, from January 2017 to December 2022. These patients underwent reoperation with MVD. The causes of recurrence were analyzed based on intraoperative findings.

Results: The causes of recurrence in the 24 patients were as follows: 10 cases due to excessive size or improper placement of the Teflon pledget compressing the facial nerve; 7 cases due to displacement or detachment of the Teflon pledget, leading to compression of the facial nerve by the original offending vessel; 3 cases due to compression by the vertebral artery with high tension, resulting in insufficient initial decompression; 3 cases due to compression by new offending vessels; and 1 case due to traction and distortion of the facial nerve caused by arachnoid adhesion and thickening. The average follow-up period was 49.2 months, with a surgical efficacy rate of 95.8% during follow-up.

Conclusion: In cases of recurrent hemifacial spasm after MVD, improper placement of the Teflon pledget, leading to compression of the facial nerve exit zone by the vessel or pledget, is the main cause. Reoperation with MVD remains safe and effective for recurrent cases. The key to successful surgery includes the surgeon's proficient microsurgical techniques, rich surgical experience, cautious and patient intraoperative manipulation, and meticulous perioperative management.

目的:探讨微血管减压(MVD)术后面肌痉挛复发的相关因素及再手术效果。方法:回顾性收集2017年1月至2022年12月苏州九龙医院神经外科MVD术后复发性面肌痉挛患者24例的临床资料。这些患者接受了MVD再手术。结合术中发现,分析复发原因。结果:24例患者复发的原因如下:10例因特氟隆纱布尺寸过大或放置不当压迫面神经所致;7例因聚四氟乙烯膜移位或脱离,导致面神经受原侵犯血管压迫;3例因椎动脉高压压迫,导致初始减压不足;新血管压迫3例;1例因蛛网膜粘连增厚引起面神经牵拉变形。平均随访49.2个月,手术有效率95.8%。结论:在MVD后复发性面肌痉挛的病例中,聚四氟乙烯质布放置不当,导致血管或质布压迫面神经出口区是主要原因。再手术与MVD仍然是安全有效的复发病例。手术成功的关键是外科医生熟练的显微外科技术、丰富的手术经验、谨慎、耐心的术中操作和细致的围手术期管理。
{"title":"Recurrent Factors and Reoperation Strategies in Microvascular Decompression for Hemifacial Spasm.","authors":"Xie Xiangtong, Zhou Shijun, Hanchun Chen, Dongyi Jiang, Yang Debao","doi":"10.1097/SCS.0000000000012502","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012502","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the factors contributing to the recurrence of hemifacial spasm after microvascular decompression (MVD) and the outcomes of reoperation with MVD.</p><p><strong>Methods: </strong>The authors retrospectively collected clinical data from 24 patients with recurrent hemifacial spasm after MVD treated at the Department of Neurosurgery, Suzhou Kowloon Hospital, from January 2017 to December 2022. These patients underwent reoperation with MVD. The causes of recurrence were analyzed based on intraoperative findings.</p><p><strong>Results: </strong>The causes of recurrence in the 24 patients were as follows: 10 cases due to excessive size or improper placement of the Teflon pledget compressing the facial nerve; 7 cases due to displacement or detachment of the Teflon pledget, leading to compression of the facial nerve by the original offending vessel; 3 cases due to compression by the vertebral artery with high tension, resulting in insufficient initial decompression; 3 cases due to compression by new offending vessels; and 1 case due to traction and distortion of the facial nerve caused by arachnoid adhesion and thickening. The average follow-up period was 49.2 months, with a surgical efficacy rate of 95.8% during follow-up.</p><p><strong>Conclusion: </strong>In cases of recurrent hemifacial spasm after MVD, improper placement of the Teflon pledget, leading to compression of the facial nerve exit zone by the vessel or pledget, is the main cause. Reoperation with MVD remains safe and effective for recurrent cases. The key to successful surgery includes the surgeon's proficient microsurgical techniques, rich surgical experience, cautious and patient intraoperative manipulation, and meticulous perioperative management.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146085917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Model for Predicting Acute Kidney Injury in Patients With Traumatic Brain Injury. 外伤性脑损伤患者急性肾损伤的预测模型
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-29 DOI: 10.1097/SCS.0000000000012497
Dadong Ding, Yinjie Gu, Yigao Wu, Penghua Hu, Chunxiang Xu, Mingge Tang, Junjie Lu, Xiaoming Wu, Lina Shao, Ying Cui, Shi Wang, Wei Fan, Hong Chu

Objective: The early detection of acute kidney injury (AKI) in patients with traumatic brain injury (TBI) may enable the prompt initiation of preventive strategies and the development of personalized treatment plans, thereby enhancing prognostic outcomes. This study seeks to develop a predictive model for AKI in TBI patients.

Methods: An analysis was conducted on data from 409 adult TBI patients treated at our hospital between January 2021 and December 2021, with the outcome being the incidence of AKI. A logistic regression model was constructed, using the least absolute shrinkage and selection operator (LASSO) regression to select optimal variables. The model's performance was assessed using several metrics, including the Brier score, the area under the receiver operating characteristic curve (AUC), calibration plots, and decision curve analysis (DCA).

Results: AKI was identified in 9.0% of the patients. The final model included 5 variables: estimated glomerular filtration rate, a Glasgow Coma Scale score of <6, mechanical ventilation upon admission, hyperuricemia, and serum cystatin C levels exceeding 1.16 mg/L. Upon validation using bootstrapping, the model exhibited robust performance, evidenced by a Brier score of 0.069 (95% CI: 0.066-0.074) and the AUC of 0.809 (95% CI: 0.760-0.823). The calibration plot demonstrated a high degree of concordance between observed outcomes and model predictions. In addition, DCA affirmed the model's clinical utility.

Conclusion: The predictive model proficiently identifies patients at elevated risk for AKI, thereby facilitating timely intervention and management.

目的:早期发现外伤性脑损伤(TBI)患者的急性肾损伤(AKI)可能有助于及时启动预防策略和制定个性化治疗计划,从而提高预后结果。本研究旨在建立脑外伤患者AKI的预测模型。方法:对2021年1月至2021年12月在我院治疗的409例成人TBI患者的数据进行分析,以AKI发生率为结果。建立logistic回归模型,利用最小绝对收缩和选择算子(LASSO)回归选择最优变量。该模型的性能通过几个指标进行评估,包括Brier评分、受试者工作特征曲线下面积(AUC)、校准图和决策曲线分析(DCA)。结果:9.0%的患者诊断为AKI。最终模型包括5个变量:肾小球滤过率估计值、格拉斯哥昏迷量表评分。结论:该预测模型能熟练识别AKI高危患者,从而促进及时干预和管理。
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引用次数: 0
Surgery First Bimaxillary Osteotomy for Marked Facial Asymmetry Developed After Aligner Treatment. 手术先行双颌截骨术治疗矫正器治疗后出现的明显面部不对称。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-29 DOI: 10.1097/SCS.0000000000012506
Noriaki Aoki, Yuki Kubo, Junichi Baba

A 28-year-old woman with facial asymmetry after aligner treatment visited our hospital. She complained of an asymmetric gummy smile and a deviated mental area developed after clear aligner treatment. On CT examination, occlusal cant was found, leading to facial asymmetry. We made a clinical diagnosis of jaw deformity with an asymmetric face, and recommended her orthognathic surgery using wire orthodontics. She accepted jaw surgery; however, she refused wire orthodontic treatment. Therefore, we selected bimaxillary osteotomy with a surgical-first approach using her clear aligner to correct the inclined occlusal plane and improve the deviated jaw. The functional occlusion could be established, and improvement of facial form could be gained with a proper occlusal plane. This case report is a rare case, in which retreatment of the surgical approach for bimaxillary osteotomy for marked facial asymmetry developed after aligner treatment. We must be aware of the necessity of thorough and careful examination to avoid misdiagnosis.

一名28岁女性,因矫正器治疗后面部不对称来我院就诊。她抱怨说,她的笑容不对称,而且在使用透明矫正器治疗后,她的精神区域出现了偏差。CT检查发现咬合不正,导致面部不对称。我们对她的临床诊断为颌骨畸形,面部不对称,并建议她使用金属丝正畸手术。她接受了下颌手术;然而,她拒绝金属丝正畸治疗。因此,我们选择手术先入路的双颌截骨术,使用她的清晰对准器来矫正倾斜的咬合平面并改善偏颌。适当的咬合平面可以建立功能性咬合,改善面部形态。本病例报告是一个罕见的病例,其中双颌截骨手术入路治疗明显的面部不对称发展后,对准器治疗。我们必须意识到彻底仔细检查的必要性,以避免误诊。
{"title":"Surgery First Bimaxillary Osteotomy for Marked Facial Asymmetry Developed After Aligner Treatment.","authors":"Noriaki Aoki, Yuki Kubo, Junichi Baba","doi":"10.1097/SCS.0000000000012506","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012506","url":null,"abstract":"<p><p>A 28-year-old woman with facial asymmetry after aligner treatment visited our hospital. She complained of an asymmetric gummy smile and a deviated mental area developed after clear aligner treatment. On CT examination, occlusal cant was found, leading to facial asymmetry. We made a clinical diagnosis of jaw deformity with an asymmetric face, and recommended her orthognathic surgery using wire orthodontics. She accepted jaw surgery; however, she refused wire orthodontic treatment. Therefore, we selected bimaxillary osteotomy with a surgical-first approach using her clear aligner to correct the inclined occlusal plane and improve the deviated jaw. The functional occlusion could be established, and improvement of facial form could be gained with a proper occlusal plane. This case report is a rare case, in which retreatment of the surgical approach for bimaxillary osteotomy for marked facial asymmetry developed after aligner treatment. We must be aware of the necessity of thorough and careful examination to avoid misdiagnosis.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146085969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sagittal Craniosynostosis Associated With Chromosome 16p13.3 Duplication. 矢状颅缝闭塞与染色体16p13.3重复有关。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-01-29 DOI: 10.1097/SCS.0000000000012485
Sarut Chaisrisawadisuk, Inthira Khampalikit, Achara Sathienkijkanchai

Sagittal craniosynostosis, the most common nonsyndromic form, typically causes scaphocephaly and occurs more often in males. This report describes a 2-month-old boy with sagittal craniosynostosis associated with a rare chromosome 16p13.3 duplication, detected by chromosomal microarray analysis despite a normal karyotype. He had dysmorphic facies, cardiac defects, and undescended testes. At 23 months, he underwent cranial vault remodeling with marked improvement; follow-up showed a normal head shape but mild developmental delay. This case underscores the value of chromosomal microarray in diagnosing syndromic craniosynostosis and highlights the need for multidisciplinary care. It represents a previously unrecognised association between chromosome 16p13.3 duplication and craniosynostosis.

矢状颅缝闭塞是最常见的非综合征性形式,通常导致舟状头畸形,多见于男性。本报告描述了一个2个月大的男孩矢状颅缝闭塞与罕见的染色体16p13.3重复相关,尽管核型正常,但通过染色体微阵列分析检测到。他有畸形相、心脏缺陷和睾丸隐退。23个月时,患者行颅拱顶重塑,明显改善;随访显示头部形状正常,但发育有轻微迟缓。本病例强调了染色体微阵列在诊断综合征性颅缝闭锁中的价值,并强调了多学科治疗的必要性。它代表了以前未被认识到的染色体16p13.3重复与颅缝闭合之间的联系。
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引用次数: 0
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Journal of Craniofacial Surgery
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