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Post-Traumatic Intravascular Papillary Endothelial Hyperplasia (Masson Tumor) of the Eyelid. 创伤后眼睑血管内乳头状内皮增生(马松瘤)。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-05 DOI: 10.1097/SCS.0000000000012528
Jeeyoon Kim, Yerin Kim, Jongweon Shin

Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson tumor, is a rare benign vascular lesion characterized by reactive endothelial proliferation within the vessel lumen. Eyelid involvement is exceedingly uncommon and may clinically mimic malignant vascular tumors. The authors report a case of post-traumatic IPEH of the eyelid in a 50-year-old man presenting with a slowly enlarging purplish nodule in the lateral canthal region. Complete surgical excision was performed. Histopathologic examination revealed tuft-like papillary endothelial proliferation confined within an expanded vein with associated thrombus, without cytologic atypia or mitotic activity, consistent with the pure type of IPEH. Immunohistochemical staining showed diffuse CD34 positivity and negative p53 expression, supporting the diagnosis and excluding angiosarcoma. No recurrence was observed during follow-up. This case underscores the extreme rarity of eyelid involvement and emphasizes that, despite a history of trauma, accurate subtype classification of IPEH relies on histopathologic rather than clinical findings.

血管内乳头状内皮增生(IPEH),也被称为马松瘤,是一种罕见的良性血管病变,其特征是血管腔内反应性内皮增生。眼睑受累极为罕见,临床上可能与恶性血管肿瘤相似。作者报告了一例创伤后眼睑IPEH在一个50岁的男子表现为一个缓慢扩大的紫色结节外侧眦区域。完成手术切除。组织病理学检查显示丛状乳头状内皮增生局限于扩张静脉内并伴有血栓,无细胞学异型性或有丝分裂活性,与纯型IPEH一致。免疫组化染色显示弥漫性CD34阳性,p53阴性表达,支持诊断,排除血管肉瘤。随访期间未见复发。该病例强调了眼睑受累的极端罕见性,并强调,尽管有创伤史,IPEH的准确亚型分类依赖于组织病理学而不是临床表现。
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引用次数: 0
The Transposed Sagittal Bandeau Technique for Correcting Scaphocephaly. 转位矢状带技术矫正舟头畸形。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-04 DOI: 10.1097/SCS.0000000000012522
Jeffrey A Fearon

Correcting the scaphocephalic skull shape caused by sagittal craniosynostosis has likely produced a wider variety of treatment approaches than any other single-suture synostosis. Considering that the goals of surgery are to enlarge the intracranial space to facilitate cerebral blood flow and to normalize appearance in all 3 dimensions, the ideal repair should safely and effectively accomplish both objectives. A technical variation on a remodeling procedure is presented, based on the creation of a sagittal bandeau, which provides the foundation for a correction that not only widens the posterior biparietal distance but also remedies the posterior reduction in skull height, resulting in both an expansion of the intracranial space and a normalization of appearance.

纠正矢状缝骨闭塞引起的舟头颅骨形状可能比任何其他单缝线缝骨闭塞产生更广泛的治疗方法。考虑到手术的目的是扩大颅内空间以促进脑血流,并使所有三个维度的外观正常化,理想的修复应安全有效地实现这两个目标。本文提出了一种基于矢状带的重塑手术的技术变化,它为矫正提供了基础,不仅扩大了后双顶骨距离,还弥补了后颅骨高度的减少,从而扩大了颅内空间,使外观正常化。
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引用次数: 0
A Novel Osteotomy Technique for Treatment of Mandibular Deficiency: A Brief Clinical Study Using the Barakat Modification. 一种治疗下颌骨缺损的新型截骨技术:Barakat改良的简短临床研究。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-04 DOI: 10.1097/SCS.0000000000012450
Khaled Ibrahim Barakat, Mostafa Mohamed Fathy, Hamed Ahmed Gad

Mandibular deficiency correction demands precise control of both advancement and rotation to achieve optimal function and facial harmony. The Barakat modification introduces an intraoral adaptation of the inverted L osteotomy, which enables simultaneous mandibular advancement and controlled counterclockwise rotation, eliminating the need for grafting and reducing morbidity. Cephalometric evaluation demonstrated consistent forward mandibular repositioning (mean SNB increase ≈ +1 degree) accompanied by reductions in FMA (≈ -3 to -5 degrees) and gonial angle (≈ -2 to -4 degrees), confirming effective rotational control with vertical shortening. Postoperative assessments revealed a stable occlusion, accurate bony alignment, and enhanced lower facial proportions, with no complications. The Barakat modification offers a predictable, minimally invasive solution for managing mandibular deficiency, combining advancement precision with rotational control to deliver superior aesthetic and functional outcomes.

下颌缺陷矫正需要精确控制前进和旋转,以达到最佳的功能和面部和谐。Barakat改良引入了倒L型截骨术的口内适应性,使下颌同时前进并控制逆时针旋转,消除了移植的需要并降低了发病率。头颅测量显示,下颌前移位(平均SNB增加≈+1度)与FMA(≈-3至-5度)和角角(≈-2至-4度)的减少一致,证实了通过垂直缩短有效地控制旋转。术后评估显示稳定的咬合,准确的骨排列,增强的下面部比例,无并发症。Barakat改良提供了可预测的、微创的解决方案来治疗下颌缺损,结合了先进的精度和旋转控制,提供了卓越的美学和功能结果。
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引用次数: 0
An Open Face in Frozen War: Lt. John Yancey, the Chosin Reservoir, and the Origins of Modern Maxillofacial Trauma Care. 冰封战争中的开放面孔:约翰·扬西中尉、长津水库和现代颌面创伤护理的起源。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-04 DOI: 10.1097/SCS.0000000000012514
Kun Hwang

The Chosin Reservoir campaign of the Korean War represents one of the most extreme environments in which modern military medicine was tested. Among its casualties was First Lieutenant John Yancey of the US Marine Corps, who sustained a devastating open facial gunshot wound with orbital destruction while defending Hill 1282 in December 1950. Remarkably, Yancey survived the initial injury, remained conscious, retained command, and continued combat operations before eventual evacuation and surgical care. This paper revisits Yancey's injury as a historical and clinical lens through which to examine the origins and ethical foundations of modern maxillofacial trauma care. Using contemporary craniofacial trauma frameworks, the injury is reconstructed as a severe open midfacial fracture with globe involvement, extreme risk of hemorrhage, infection, and airway compromise. Survival was contingent on a confluence of factors: sparing of major vascular and neural structures, environmental vasoconstriction, evolving evacuation systems, and surgical principles refined during the World Wars by pioneers such as Gillies and McIndoe. Beyond technique, Yancey's case foregrounds enduring ethical questions central to facial trauma surgery-identity, dignity, and the limits of reconstruction. His continued leadership despite permanent facial loss underscores that reconstructive success cannot be measured solely by aesthetic restoration. For contemporary craniofacial surgeons practicing in an era increasingly shaped by elective aesthetics, revisiting such wartime cases restores clarity of purpose. Maxillofacial surgery was forged not to perfect faces, but to save lives and preserve function under conditions of profound scarcity. Remembering this lineage remains essential to maintaining the ethical core of the specialty.

朝鲜战争时期的长津水库战役是检验现代军事医学的最极端环境之一。1950年12月,美国海军陆战队中尉约翰·扬西(John Yancey)在保卫1282号山(Hill 1282)时,面部遭受了毁灭性的开放性枪伤,眼眶被毁。值得注意的是,扬西在最初的受伤中幸存下来,保持清醒,保留了指挥权,并在最终撤离和手术治疗之前继续战斗行动。本文从历史和临床的角度重新审视了扬西的创伤,通过它来审视现代颌面创伤护理的起源和伦理基础。使用现代颅面外伤框架,该损伤被重建为严重的开放性面中骨折,伴有球体受损伤,出血、感染和气道损伤的极端风险。存活取决于多种因素:保留主要的血管和神经结构,环境血管收缩,不断发展的疏散系统,以及在世界大战期间由Gillies和McIndoe等先驱改进的手术原理。除了技术之外,Yancey的案例凸显了面部创伤手术中经久不衰的伦理问题——身份、尊严和重建的局限性。尽管他的面部永久性受损,但他的持续领导强调了重建的成功不能仅仅通过美学修复来衡量。对于当代颅面外科医生来说,在一个越来越受选择性美学影响的时代,重新审视这些战时病例可以恢复目的的清晰度。颌面外科手术不是为了完美的脸,而是为了在极度匮乏的条件下挽救生命和保持功能。记住这一血统对于维持该专业的道德核心至关重要。
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引用次数: 0
Comparison of Using Palatal and Lingual Flaps to Repair Acquired Medium to Large-Size Hard Palate Defects Based on a Grid Palatal Horizontal Plane Palatal Defect Classification System. 基于栅格腭水平面腭缺损分类系统的腭瓣与舌瓣修复获得性中、大尺寸硬腭缺损的比较。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-03 DOI: 10.1097/SCS.0000000000012511
Wei-Liang Chen, Zi-Xian Huang, Rui Chen

Objective: This study aimed to compare the clinical outcomes of repairing acquired palatal defects using palatal island rotation flaps (PRFs) or anteriorly based dorsal tongue flaps (aTFs).

Methods: In total, 39 patients (23 males and 16 females) aged 22 to 74 years (median: 48.4 y) were included. According to the grid-based palatal horizontal plane palatal defect classification system, palatal defects were divided into 3 classes (classes I, II, and III); hard palate defects (classes I and II) were further subdivided into 3 subtypes (a, b, and c). Medium and large-sized defects accounted for 56.4% and 43.6% of the cases, respectively. A circumferential incision was made at the margin of the hard palate defect to create marginal buccal and palatal or cheek flaps, which were infolded to form an intranasal lining. Subsequently, either a PRF (59.0%) or an aTF (41.0%) was prepared to form the intraoral lining. The dimensions of the PRFs and aTFs ranged from 1.2×2.2 to 1.4×2.4 cm and from 1.8×2.8 to 2.4×3.2 cm, respectively. Swallowing and speech functions were evaluated at 3 months postoperatively.

Results: The dimensions of the aTFs were significantly larger than those of the PRFs (median: 2.2×3.0 cm versus 1.3×2.3 cm, P < 0.05). Postoperative complications, such as hemorrhage or bleeding, dehiscence or fistula formation, and partial flap necrosis, were significantly more common in the PRF group than in the aTF group (43.5% versus 12.5%, P < 0.05). The proportion of patients achieving postoperative swallowing and speech function scores of 3 was significantly higher than the proportion based on preoperative scores (P < 0.05). Furthermore, patients with medium-sized defects demonstrated significantly higher rates of achieving postoperative swallowing and speech function scores of 3 compared with those with large-sized defects (P < 0.05).

Conclusions: Both PRFs and aTFs are effective for reconstructing acquired medium to large-sized hard palate defects based on the grid palatal horizontal plane palatal defect classification system. However, aTFs offer advantages for larger defects, with a lower incidence of postoperative complications.

目的:比较腭岛状旋转瓣(PRFs)与前基舌背瓣(aTFs)修复获得性腭缺损的临床效果。方法:共纳入39例患者(男23例,女16例),年龄22 ~ 74岁,中位数48.4岁。根据基于网格的腭水平面腭缺陷分类系统,将腭缺陷分为3类(ⅰ、ⅱ、ⅲ类);将硬腭缺损(ⅰ、ⅱ类)进一步细分为a、b、c 3个亚型。中型和大型缺陷分别占56.4%和43.6%。在硬腭缺损的边缘作圆周切口,形成颊缘和腭缘或颊缘皮瓣,并将其折叠形成鼻内衬。随后,制备PRF(59.0%)或aTF(41.0%)形成口腔内衬。PRFs和aTFs的尺寸分别为1.2×2.2 ~ 1.4×2.4 cm和1.8×2.8 ~ 2.4×3.2 cm。术后3个月评估吞咽和语言功能。结果:aTFs的尺寸明显大于PRFs(中位数:2.2×3.0 cm vs 1.3×2.3 cm, P < 0.05)。PRF组术后并发症如大出血、裂口或瘘形成、部分皮瓣坏死发生率明显高于aTF组(43.5%比12.5%,P < 0.05)。术后吞咽和言语功能评分为3分的患者比例显著高于术前评分的患者比例(P < 0.05)。中等大小缺损患者术后吞咽和言语功能得分达到3分的比例明显高于大尺寸缺损患者(P < 0.05)。结论:基于栅格腭水平面腭缺损分类系统的PRFs和aTFs均可有效修复获得性中、大型硬腭缺损。然而,对于较大的缺损,atf具有较低的术后并发症发生率的优势。
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引用次数: 0
Artificial Intelligence Is Reshaping Craniofacial Surgery Treatment Pathways in China. 人工智能正在重塑中国颅面外科治疗途径。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-03 DOI: 10.1097/SCS.0000000000012508
Haisong Xu
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引用次数: 0
Radiologic and Anatomic Evaluation of the Temporomandibular Joint in Individuals With and Without Temporomandibular Dysfunction. 有或无颞下颌关节功能障碍个体的颞下颌关节放射学和解剖学评价。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-03 DOI: 10.1097/SCS.0000000000012494
Serdil Sayilkan, Çağatay Bölgen, Pinar Göker

Objectives: This study aimed to investigate the relationship between palate morphology, masticatory muscle thickness, choanae structure, and sphenoidale foramina in individuals with temporomandibular dysfunction (TMD), and to determine how variations in these parameters affect temporomandibular joint (TMJ) function.

Methods: Cone beam computed tomography (CBCT) scans of 36 individuals with TMD and 36 healthy controls, aged 18 to 69 years, were retrospectively analyzed. The possible relationships between TMD and the morphometry of the hard palate, nasi choanae, and sphenoidale foramina were evaluated, and thickness measurements of the masticatory muscles (masseter, temporalis, lateral, and medial pterygoideus) were also correlated with TMD.

Results: Significant relationships were found between TMD and the morphometric features of the craniofacial structures. Statistically significant relationships were found between age and the masseter, temporalis, and medial pterygoid muscle thicknesses in individuals who had TMD (P<0.05). In addition, a significant difference was observed in the hard palate transverse width according to gender in the TMD group (P<0.05). In the control group, a significant relationship was found between medial pterygoid thickness on both sides and left foramen ovale length and hard palate transverse width values depending on gender (P<0.05). Significant differences were found in foramen rotundum width measurements in the comparison of the TMD and control groups (P<0.05).

Conclusion: This study demonstrates the relationship between craniofacial morphology, masticatory muscle thickness, and TMD. The findings suggest that anatomic features of the hard palate and sphenoid region may contribute to TMJ function and deepen the understanding of TMD's structural basis.

目的:本研究旨在探讨颞下颌关节功能障碍(TMD)患者的腭形态、咀嚼肌厚度、choanae结构和蝶孔之间的关系,并确定这些参数的变化如何影响颞下颌关节(TMJ)功能。方法:回顾性分析36例TMD患者和36例年龄在18 ~ 69岁的健康对照者的锥形束计算机断层扫描(CBCT)。我们评估了TMD与硬腭、鼻窦和蝶孔形态学之间的可能关系,并且咀嚼肌(咬肌、颞肌、外侧和内侧翼状肌)的厚度测量也与TMD相关。结果:TMD与颅面结构形态特征有显著相关性。年龄与TMD患者的咬肌、颞肌和内侧翼状肌厚度之间存在统计学意义上的关系(结论:本研究证实颅面形态、咀嚼肌厚度与TMD之间存在关系。研究结果提示,硬腭和蝶骨区的解剖特征可能与颞下颌关节功能有关,加深了对颞下颌关节结构基础的认识。
{"title":"Radiologic and Anatomic Evaluation of the Temporomandibular Joint in Individuals With and Without Temporomandibular Dysfunction.","authors":"Serdil Sayilkan, Çağatay Bölgen, Pinar Göker","doi":"10.1097/SCS.0000000000012494","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012494","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the relationship between palate morphology, masticatory muscle thickness, choanae structure, and sphenoidale foramina in individuals with temporomandibular dysfunction (TMD), and to determine how variations in these parameters affect temporomandibular joint (TMJ) function.</p><p><strong>Methods: </strong>Cone beam computed tomography (CBCT) scans of 36 individuals with TMD and 36 healthy controls, aged 18 to 69 years, were retrospectively analyzed. The possible relationships between TMD and the morphometry of the hard palate, nasi choanae, and sphenoidale foramina were evaluated, and thickness measurements of the masticatory muscles (masseter, temporalis, lateral, and medial pterygoideus) were also correlated with TMD.</p><p><strong>Results: </strong>Significant relationships were found between TMD and the morphometric features of the craniofacial structures. Statistically significant relationships were found between age and the masseter, temporalis, and medial pterygoid muscle thicknesses in individuals who had TMD (P<0.05). In addition, a significant difference was observed in the hard palate transverse width according to gender in the TMD group (P<0.05). In the control group, a significant relationship was found between medial pterygoid thickness on both sides and left foramen ovale length and hard palate transverse width values depending on gender (P<0.05). Significant differences were found in foramen rotundum width measurements in the comparison of the TMD and control groups (P<0.05).</p><p><strong>Conclusion: </strong>This study demonstrates the relationship between craniofacial morphology, masticatory muscle thickness, and TMD. The findings suggest that anatomic features of the hard palate and sphenoid region may contribute to TMJ function and deepen the understanding of TMD's structural basis.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ventral Compression of the Trigeminal Nerve by the Superior Cerebellar Artery: A Novel Intraoperative Classification and Clinical Significance. 小脑上动脉压迫三叉神经腹侧:一种新的术中分型及临床意义。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-02 DOI: 10.1097/SCS.0000000000012505
Pan Li, Yong Xiao, Wenxiong Song, Feiyu Ding, Yong Liu, Liang Liu, Dong Wang, Ran Wang, Liangyuan Geng, Yuanjie Zou

Objective: The superior cerebellar artery (SCA) is the most common offending vessel in microvascular decompression (MVD) for trigeminal neuralgia (TN). Among its variations, ventral compression presents unique surgical challenges, yet systematic classification remains limited. This study aimed to establish a novel intraoperative classification of ventral SCA compression and to evaluate its surgical and clinical relevance.

Methods: We retrospectively reviewed patients with TN who underwent MVD by the senior author between February 2019 and February 2024. Intraoperative video recordings were analyzed to categorize ventral-type SCA compression into 4 subtypes, based on the anatomic relationship with the trigeminal nerve and the facial-vestibulocochlear nerve complex. Patient demographics, operative findings, decompression techniques, and postoperative outcomes were compared across subtypes.

Results: Eighty-eight patients with SCA compression were identified and classified into 4 subtypes: type 0 (36.4%), SCA rostral to the trigeminal nerve; type I (35.2%), SCA ventral to the nerve without extending below its inferior border; type II (18.2%), SCA looping ventrally with its lowest point between the trigeminal and facial-vestibulocochlear nerves; and type III (10.2%), SCA extending ventrally beyond the superior border of the facial-vestibulocochlear complex. No statistically significant differences were observed in postoperative pain relief or complication rates across subtypes (P>0.05). However, surgical complexity varied considerably, with hidden compression at the trigeminal root entry zone and excessive vascular tortuosity contributing to greater intraoperative difficulty. Tailored surgical strategies, including the "push-and-flip" technique, enabled safe and effective decompression.

Conclusions: This study proposes a novel intraoperative classification of ventral SCA compression in TN. While short-term clinical outcomes were similar across subtypes, the classification emphasizes key anatomic variations that significantly affect surgical complexity. Recognition of these subtypes may facilitate operative planning, improve surgical safety, and reduce the risk of recurrence in patients undergoing MVD.

目的:小脑上动脉(SCA)是三叉神经痛(TN)微血管减压(MVD)中最常见的累犯血管。在其变体中,腹侧压迫呈现出独特的手术挑战,但系统的分类仍然有限。本研究旨在建立一种新的术中腹侧SCA压迫分类,并评估其手术和临床意义。方法:我们回顾性分析了资深作者在2019年2月至2024年2月期间接受MVD的TN患者。分析术中视频记录,根据与三叉神经和面前庭耳蜗神经复合体的解剖关系,将腹侧型SCA压迫分为4个亚型。患者人口统计学、手术发现、减压技术和不同亚型的术后结果进行了比较。结果:88例SCA压迫患者经鉴定分为4个亚型:0型(36.4%),SCA吻侧至三叉神经;I型(35.2%),SCA位于神经腹侧,未延伸至其下缘以下;II型(18.2%),SCA腹侧环行,最低点位于三叉神经和面神经-前庭耳蜗神经之间;III型(10.2%),SCA向腹侧延伸,超出面-前庭-耳蜗复合体的上边界。两组患者术后疼痛缓解及并发症发生率差异无统计学意义(P < 0.05)。然而,手术复杂性差异很大,三叉神经根进入区隐藏的压迫和过度的血管弯曲增加了术中难度。量身定制的手术策略,包括“推翻”技术,使减压安全有效。结论:本研究提出了一种新的TN腹侧SCA压迫术中分类方法。尽管各亚型的短期临床结果相似,但该分类强调了影响手术复杂性的关键解剖差异。对这些亚型的认识可以促进手术计划,提高手术安全性,降低MVD患者的复发风险。
{"title":"Ventral Compression of the Trigeminal Nerve by the Superior Cerebellar Artery: A Novel Intraoperative Classification and Clinical Significance.","authors":"Pan Li, Yong Xiao, Wenxiong Song, Feiyu Ding, Yong Liu, Liang Liu, Dong Wang, Ran Wang, Liangyuan Geng, Yuanjie Zou","doi":"10.1097/SCS.0000000000012505","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012505","url":null,"abstract":"<p><strong>Objective: </strong>The superior cerebellar artery (SCA) is the most common offending vessel in microvascular decompression (MVD) for trigeminal neuralgia (TN). Among its variations, ventral compression presents unique surgical challenges, yet systematic classification remains limited. This study aimed to establish a novel intraoperative classification of ventral SCA compression and to evaluate its surgical and clinical relevance.</p><p><strong>Methods: </strong>We retrospectively reviewed patients with TN who underwent MVD by the senior author between February 2019 and February 2024. Intraoperative video recordings were analyzed to categorize ventral-type SCA compression into 4 subtypes, based on the anatomic relationship with the trigeminal nerve and the facial-vestibulocochlear nerve complex. Patient demographics, operative findings, decompression techniques, and postoperative outcomes were compared across subtypes.</p><p><strong>Results: </strong>Eighty-eight patients with SCA compression were identified and classified into 4 subtypes: type 0 (36.4%), SCA rostral to the trigeminal nerve; type I (35.2%), SCA ventral to the nerve without extending below its inferior border; type II (18.2%), SCA looping ventrally with its lowest point between the trigeminal and facial-vestibulocochlear nerves; and type III (10.2%), SCA extending ventrally beyond the superior border of the facial-vestibulocochlear complex. No statistically significant differences were observed in postoperative pain relief or complication rates across subtypes (P>0.05). However, surgical complexity varied considerably, with hidden compression at the trigeminal root entry zone and excessive vascular tortuosity contributing to greater intraoperative difficulty. Tailored surgical strategies, including the \"push-and-flip\" technique, enabled safe and effective decompression.</p><p><strong>Conclusions: </strong>This study proposes a novel intraoperative classification of ventral SCA compression in TN. While short-term clinical outcomes were similar across subtypes, the classification emphasizes key anatomic variations that significantly affect surgical complexity. Recognition of these subtypes may facilitate operative planning, improve surgical safety, and reduce the risk of recurrence in patients undergoing MVD.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Xinghanxiang Nasal Inhalation Therapy on Obstructive Sleep Apnea-Hypopnea Syndrome and Upper Airway Inflammation. 醒汉香鼻吸入治疗阻塞性睡眠呼吸暂停低通气综合征及上呼吸道炎症的疗效观察。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-02 DOI: 10.1097/SCS.0000000000012498
Xiao-Jing Liu, Quan Li, Xiao-Ming Yang, Xin-Li Chen, Chuan-Feng Liu, Tao Sun, Zhong-Da Liu

Objective: This study aimed to evaluate the efficacy of Xinghanxiang nasal inhalation therapy in treating obstructive sleep apnea-hypopnea syndrome (OSAHS) and its effects on upper airway inflammation.

Methods: A total of 180 patients with OSAHS were matched according to disease severity and randomly divided into a control group and an intervention group, with 90 patients in each group. In the control group, patients with mild OSAHS received routine therapy, whereas those with moderate to severe OSAHS received continuous positive airway pressure (CPAP) therapy. In the intervention group, patients with mild OSAHS received routine therapy plus Xinghanxiang nasal inhalation therapy, and those with moderate to severe OSAHS received routine therapy combined with Xinghanxiang nasal inhalation therapy along with CPAP therapy. Clinical symptoms, the Epworth Sleepiness Scale (ESS), apnea-hypopnea index (AHI), and levels of C-reactive protein (CRP) and interleukin (IL)-6 in nasal lavage fluid were evaluated.

Results: Both groups demonstrated significant improvements in clinical symptoms (including quality-of-life scores), ESS, and AHI compared with baseline (P<0.05), with greater improvement observed in the intervention group (P<0.05). CRP and IL-6 levels in nasal lavage fluid decreased significantly in both groups after treatment, with more pronounced reductions in the intervention group (P<0.05). CRP levels in nasal lavage fluid were lower in the intervention group than in the control group (P<0.05). IL-6 levels in nasal lavage fluid were significantly lower in patients with moderate to severe disease in the intervention group compared with the control group (P<0.05), whereas no significant difference was observed in patients with mild disease (P>0.05).

Conclusions: Xinghanxiang nasal inhalation therapy significantly improves clinical symptoms in patients with OSAHS. Combined therapy with CPAP further improves ESS and AHI, with no significant adverse effects, supporting the need for large-scale studies and broader clinical application. Furthermore, Xinghanxiang nasal inhalation therapy significantly reduces CRP and IL-6 levels in nasal lavage fluid, suggesting that its mechanism of action may be related to alleviation of upper airway inflammation.

目的:探讨醒汉香鼻吸入疗法治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效及对上呼吸道炎症的影响。方法:将180例OSAHS患者按病情严重程度进行匹配,随机分为对照组和干预组,每组90例。在对照组中,轻度OSAHS患者接受常规治疗,中度至重度OSAHS患者接受持续气道正压通气(CPAP)治疗。在干预组中,轻度OSAHS患者给予常规治疗加星汉香鼻吸入治疗,中重度OSAHS患者给予常规治疗加星汉香鼻吸入治疗加CPAP治疗。评估临床症状、Epworth嗜睡量表(ESS)、呼吸暂停低通气指数(AHI)、鼻灌洗液中c反应蛋白(CRP)和白细胞介素(IL)-6水平。结果:与基线相比,两组患者的临床症状(包括生活质量评分)、ESS和AHI均有显著改善(P0.05)。结论:醒汉香鼻吸入治疗可显著改善OSAHS患者的临床症状。联合CPAP治疗可进一步改善ESS和AHI,且无明显不良反应,支持大规模研究和更广泛临床应用的需求。此外,星汉香鼻吸入治疗可显著降低鼻灌洗液中CRP和IL-6水平,提示其作用机制可能与缓解上呼吸道炎症有关。
{"title":"Effects of Xinghanxiang Nasal Inhalation Therapy on Obstructive Sleep Apnea-Hypopnea Syndrome and Upper Airway Inflammation.","authors":"Xiao-Jing Liu, Quan Li, Xiao-Ming Yang, Xin-Li Chen, Chuan-Feng Liu, Tao Sun, Zhong-Da Liu","doi":"10.1097/SCS.0000000000012498","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012498","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the efficacy of Xinghanxiang nasal inhalation therapy in treating obstructive sleep apnea-hypopnea syndrome (OSAHS) and its effects on upper airway inflammation.</p><p><strong>Methods: </strong>A total of 180 patients with OSAHS were matched according to disease severity and randomly divided into a control group and an intervention group, with 90 patients in each group. In the control group, patients with mild OSAHS received routine therapy, whereas those with moderate to severe OSAHS received continuous positive airway pressure (CPAP) therapy. In the intervention group, patients with mild OSAHS received routine therapy plus Xinghanxiang nasal inhalation therapy, and those with moderate to severe OSAHS received routine therapy combined with Xinghanxiang nasal inhalation therapy along with CPAP therapy. Clinical symptoms, the Epworth Sleepiness Scale (ESS), apnea-hypopnea index (AHI), and levels of C-reactive protein (CRP) and interleukin (IL)-6 in nasal lavage fluid were evaluated.</p><p><strong>Results: </strong>Both groups demonstrated significant improvements in clinical symptoms (including quality-of-life scores), ESS, and AHI compared with baseline (P<0.05), with greater improvement observed in the intervention group (P<0.05). CRP and IL-6 levels in nasal lavage fluid decreased significantly in both groups after treatment, with more pronounced reductions in the intervention group (P<0.05). CRP levels in nasal lavage fluid were lower in the intervention group than in the control group (P<0.05). IL-6 levels in nasal lavage fluid were significantly lower in patients with moderate to severe disease in the intervention group compared with the control group (P<0.05), whereas no significant difference was observed in patients with mild disease (P>0.05).</p><p><strong>Conclusions: </strong>Xinghanxiang nasal inhalation therapy significantly improves clinical symptoms in patients with OSAHS. Combined therapy with CPAP further improves ESS and AHI, with no significant adverse effects, supporting the need for large-scale studies and broader clinical application. Furthermore, Xinghanxiang nasal inhalation therapy significantly reduces CRP and IL-6 levels in nasal lavage fluid, suggesting that its mechanism of action may be related to alleviation of upper airway inflammation.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Management of Craniosynostosis: A Nordic Pediatric Neurosurgery Network Study. 颅缝闭合的当前管理:北欧儿童神经外科网络研究。
IF 1 4区 医学 Q3 SURGERY Pub Date : 2026-02-02 DOI: 10.1097/SCS.0000000000012499
Kasper Amund Henriksen, Ulrikke Wiig, Daniel Nilsson, Lars Kölby, Daniel Nowinski, Ingvar Hákon Ólafsson, Atte Karppinen, Susanna Rantala, Niina Salokorpi, Liisi Ripatti, Rauhala Minna Johanna, Gorm Von Oettingen, Lars Bøgeskov, Bernt J Due-Tønnessen, Radek Frič, Jon Foss-Skiftesvik

Historically, management of craniosynostosis (CS) has been marked by substantial variation. Although recent advances in diagnostics, minimally invasive techniques, and computer-assisted planning might be expected to promote greater uniformity, significant differences persist, as shown in a large US survey of current practice patterns. To clarify the extent of heterogeneity in the Nordic countries (28 million inhabitants), the authors conducted a comprehensive survey of all centers treating CS in the region. All 11 centers responded (100%). Marked heterogeneity was evident across organizational structures, preferred surgical techniques, and follow-up routines. Although Norway has fully centralized treatment of CS, Denmark and Sweden divide management between 2 high-volume centers each, and Finland uses a mixed model combining major reference centers with smaller regional units. Surgical management of isolated sagittal synostosis also varies substantially, ranging from minimally invasive suturectomy with postoperative helmet therapy (9%) and spring-assisted cranioplasty (27%) to open suturectomy/strip craniectomy (9%) and more extensive cranial vault remodeling including H-craniectomy (55%). Syndromic and multi-suture cases are generally managed in multidisciplinary settings, although team composition differs between centers. Additional variation was seen in the use of computer-assisted planning, 3D models, intraoperative cutting guides, postoperative imaging, neurocognitive testing, craniometry, and patient-reported or parent-reported outcome measures. Despite advances in surgical techniques and technology, CS management across the Nordic region remains highly heterogeneous. Whether this variation affects neurocognitive, cosmetic, or functional outcomes is unknown. Future collaborative research will be essential to harmonize care and ensure optimal outcomes for children with craniosynostosis.

从历史上看,颅缝闭锁(CS)的治疗方法有很大的不同。尽管最近在诊断、微创技术和计算机辅助规划方面的进展有望促进更大的一致性,但正如美国对当前实践模式的大型调查所显示的那样,显著差异仍然存在。为了弄清北欧国家(2800万居民)的异质性程度,作者对该地区所有治疗CS的中心进行了全面调查。11个中心全部回复(100%)。在组织结构、首选手术技术和随访常规中,明显存在异质性。虽然挪威完全集中治疗CS,但丹麦和瑞典将管理分为两个大容量中心,芬兰采用混合模式,将主要参考中心与较小的区域单位结合起来。孤立矢状面滑膜闭锁的手术治疗也有很大的不同,从微创缝合术加术后头盔治疗(9%)和弹簧辅助颅骨成形术(27%)到开放式缝合术/条形颅骨切除术(9%)和更广泛的颅拱顶重塑包括h型颅骨切除术(55%)。综合征和多次缝合病例通常在多学科环境下进行管理,尽管各中心的团队组成不同。在使用计算机辅助计划、3D模型、术中切割指南、术后成像、神经认知测试、颅骨测量以及患者报告或家长报告的结果测量方面也存在其他差异。尽管外科技术和技术取得了进步,但整个北欧地区的CS管理仍然高度多样化。这种变异是否会影响神经认知、美容或功能结果尚不清楚。未来的合作研究将是至关重要的协调护理和确保最佳结果的儿童颅缝闭锁。
{"title":"Current Management of Craniosynostosis: A Nordic Pediatric Neurosurgery Network Study.","authors":"Kasper Amund Henriksen, Ulrikke Wiig, Daniel Nilsson, Lars Kölby, Daniel Nowinski, Ingvar Hákon Ólafsson, Atte Karppinen, Susanna Rantala, Niina Salokorpi, Liisi Ripatti, Rauhala Minna Johanna, Gorm Von Oettingen, Lars Bøgeskov, Bernt J Due-Tønnessen, Radek Frič, Jon Foss-Skiftesvik","doi":"10.1097/SCS.0000000000012499","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012499","url":null,"abstract":"<p><p>Historically, management of craniosynostosis (CS) has been marked by substantial variation. Although recent advances in diagnostics, minimally invasive techniques, and computer-assisted planning might be expected to promote greater uniformity, significant differences persist, as shown in a large US survey of current practice patterns. To clarify the extent of heterogeneity in the Nordic countries (28 million inhabitants), the authors conducted a comprehensive survey of all centers treating CS in the region. All 11 centers responded (100%). Marked heterogeneity was evident across organizational structures, preferred surgical techniques, and follow-up routines. Although Norway has fully centralized treatment of CS, Denmark and Sweden divide management between 2 high-volume centers each, and Finland uses a mixed model combining major reference centers with smaller regional units. Surgical management of isolated sagittal synostosis also varies substantially, ranging from minimally invasive suturectomy with postoperative helmet therapy (9%) and spring-assisted cranioplasty (27%) to open suturectomy/strip craniectomy (9%) and more extensive cranial vault remodeling including H-craniectomy (55%). Syndromic and multi-suture cases are generally managed in multidisciplinary settings, although team composition differs between centers. Additional variation was seen in the use of computer-assisted planning, 3D models, intraoperative cutting guides, postoperative imaging, neurocognitive testing, craniometry, and patient-reported or parent-reported outcome measures. Despite advances in surgical techniques and technology, CS management across the Nordic region remains highly heterogeneous. Whether this variation affects neurocognitive, cosmetic, or functional outcomes is unknown. Future collaborative research will be essential to harmonize care and ensure optimal outcomes for children with craniosynostosis.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Craniofacial Surgery
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