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Nutritional Status’ Impact on the Management of Vesical Calculi: A Systematic Review of a Twenty-Two-Year Database 营养状况对膀胱结石治疗的影响:对22年数据库的系统回顾
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/60977.18632
Harshal Madavi, Hemant Chaudhari
Introduction: Acidogenic diets cause a drop in urinary pH, and increasing features of metabolic syndrome are associated with increased calcium oxalate precipitation. Nowadays, it is well accepted that dietary variables promote the formation of vesical calculi, contributing to the prevalence of vesical stones. Aim: The aim of this study is to estimate the impact of nutritional status on the management of vesical calculi. Materials and Methods: A literature search was conducted in PubMed, Medline, Web of Science, Cochrane library, as well as additional sources such as Google Scholar and ClinicalTrials. gov, covering the period from 2001 to 2022. The most important electronic databases were checked, and all types of studies, including expressive studies, trials, commentaries, and editorials, were considered due to the nature of the studies. The risk of bias was assessed using the recommended methodology. A two-part tool was used to address five specific domains: selection bias, performance bias, attrition bias, selective reporting, and other biases. Quality diagnostic accuracy studies were evaluated using a quality assessment tool. Results: This study included 12 literature sources, of which five were nutrition-based studies and seven were focused on vesical calculi. Dietary modifications and medical treatments were found to be the most important factors in preventing recurrence. Conclusion: Dietary and medical treatments are of utmost importance in preventing recurrence. As per physician advice for vesical calculi, a proper dietary plan that includes a mineralrich diet is needed. Consumption of ample fluids is essential for the removal of stones.
导言:致酸性饮食导致尿pH值下降,代谢综合征的特征增加与草酸钙沉淀增加有关。目前,人们普遍认为饮食变化会促进膀胱结石的形成,从而导致膀胱结石的发生。目的:本研究的目的是评估营养状况对膀胱结石治疗的影响。材料和方法:在PubMed、Medline、Web of Science、Cochrane图书馆以及Google Scholar和ClinicalTrials等其他来源进行文献检索。Gov,涵盖2001年至2022年期间。我们检查了最重要的电子数据库,并根据研究的性质考虑了所有类型的研究,包括表达性研究、试验、评论和社论。采用推荐的方法评估偏倚风险。一个由两部分组成的工具用于解决五个特定领域:选择偏差、绩效偏差、流失偏差、选择性报告和其他偏差。使用质量评估工具评估诊断准确性研究的质量。结果:本研究纳入12篇文献,其中5篇为营养基础研究,7篇为膀胱结石研究。饮食调整和药物治疗是预防复发的最重要因素。结论:饮食和药物治疗对预防复发至关重要。根据医生对膀胱结石的建议,适当的饮食计划包括富含矿物质的饮食是必要的。摄取充足的液体对于清除结石是必不可少的。
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引用次数: 0
Comparison of Nolla’s Method, Cameriere’s Indian-specific Method, and Acharya’s Indianspecific Regression Formula for Estimation of Dental Age in Puducherry and Cuddalore Population, Southern India 印度南部Puducherry和Cuddalore人口牙齿年龄估算的Nolla方法、Cameriere印度特有方法和Acharya印度特有回归公式的比较
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/63394.18385
R S Priya, RC Jagat Reddy, S Vandana, T Sivasankari, A Vani Anusha
Introduction: Forensic dental age estimation plays a vital role in determining the identity of a deceased individual. There are numerous dental age estimation methods available to estimate dental age using radiographs based on tooth maturation. Aim: To compare Nolla’s method, Cameriere’s Indian-specific method, and Acharya’s Indian-specific regression formula in estimating dental age in the Puducherry and Cuddalore populations of South India. Materials and Methods: This retrospective study was conducted in the Department of Oral Medicine and Radiology at the Indira Gandhi Institute of Dental Sciences, Puducherry, India, between January 2021 and October 2022. The study included 448 panoramic radiographs (202 males and 246 females) of individuals aged between six and 17 years. Chronological age was recorded based on the subject’s date of birth. Dental age was estimated using Nolla’s method, Acharya’s Indian-specific regression formula, and Cameriere’s Indian-specific method. Two qualified and experienced oral radiologists evaluated all the samples to assess their reliability. Data were analysed using descriptive statistics, the Pearson’s correlation coefficient, and Student’s t-test. Results: Nolla’s method (excluding the third molar) revealed a mean age of 13.52±3.15 years, while Nolla’s method (including the third molar) revealed a mean age of 12.81±2.84 years. Acharya’s Indian-specific method revealed a mean age of 15.08±2.92 years, and Cameriere’s Indian-specific regression formula revealed a mean age of 11.51±2.19 years. The results showed that the age estimated by Nolla’s method (including the third molar) had a p-value of 0.93 (>0.05), indicating no significant differences between the estimated dental age and chronological age. The r-values for Acharya’s Indian-specific regression formula, Nolla’s method (excluding the third molar), Nolla’s method (including the third molar), and Cameriere’s Indian-specific method were found to be 0.682, 0.885, 0.847, and 0.849, respectively, indicating a strong positive correlation among the age estimation methods. Conclusion: Nolla’s method (including the third molar) was found to be the most accurate method for dental age estimation when compared with the other three methods in the Puducherry and Cuddalore populations.
法医牙科年龄估计在确定死者身份方面起着至关重要的作用。有许多牙龄估计方法可用来估计牙龄使用基于牙齿成熟的x光片。目的:比较Nolla的方法、Cameriere的印度特有方法和Acharya的印度特有回归公式在估计印度南部Puducherry和Cuddalore人群的牙齿年龄。材料和方法:本回顾性研究于2021年1月至2022年10月在印度普杜切里英迪拉甘地牙科科学研究所口腔医学和放射学系进行。该研究包括448张全景x线片(男性202张,女性246张),年龄在6至17岁之间。实足年龄是根据受试者的出生日期记录的。使用Nolla的方法、Acharya的印度特有回归公式和Cameriere的印度特有方法估计牙齿年龄。两名合格且经验丰富的口腔放射科医生对所有样本进行了评估,以评估其可靠性。数据分析采用描述性统计、Pearson相关系数和学生t检验。结果:Nolla法(不含第三磨牙)平均年龄为13.52±3.15岁,Nolla法(含第三磨牙)平均年龄为12.81±2.84岁。Acharya的印度特异性方法显示平均年龄为15.08±2.92岁,Cameriere的印度特异性回归公式显示平均年龄为11.51±2.19岁。结果显示,Nolla法估算的年龄(包括第三磨牙)的p值为0.93 (>0.05),表明估算的牙龄与实足年龄无显著差异。Acharya的印度特异性回归公式、Nolla的方法(不包括第三磨牙)、Nolla的方法(包括第三磨牙)和Cameriere的印度特异性回归公式的r值分别为0.682、0.885、0.847和0.849,表明年龄估计方法之间存在较强的正相关。结论:在Puducherry和Cuddalore人群中,Nolla法(包括第三磨牙)与其他三种方法相比,是最准确的牙龄估计方法。
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引用次数: 0
Efficacy of Apnoeic Oxygenation by Nasal Prongs in Preventing Desaturation during Airway Management in Infants Undergoing General Anaesthesia: A Randomised Controlled Study 一项随机对照研究:在全麻婴儿气道管理过程中,鼻尖通气对防止气道失饱和的疗效
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/65714.18381
Nisha S Shetty, Pachha Priya, Krishna Rathod, S Bala Bhaskar, D Srinivasalu, N Kiran Chand, IC Devaraj
Introduction: Neonates and infants are more prone to desaturation during the apnoeic period of laryngoscopy and intubation. Various options exist to reduce this risk beyond conventional preoxygenation. Aim: To assess whether continuous apnoeic oxygenation via nasal prongs during intubation can extend the safe apnoea period compared to standard management with preoxygenation alone. Materials and Methods: A randomised controlled, two-group parallel clinical study was conducted at the Department of Anaesthesiology, Vijayanagar Institute of Medical Sciences, Ballari, Karnataka, India, from July 2019 to November 2020. The study involved 63 infants aged one day to six months undergoing elective or emergency surgeries under general anaesthesia. Preoxygenation via a mask was followed by sevoflurane induction and vecuronium-induced muscle relaxation. Conventional laryngoscopy and intubation were performed in 32 infants in Group-C (Control group), while 31 infants in Group-O (Apnoeic Oxygenation group) also received oxygen (O2 ) via nasal prongs at 4 L/min in addition to preoxygenation. The primary outcome parameter was the time taken for desaturation by 1%. The time taken to desaturate by 2%, 3%, 4%, and 5%, as well as their incidences, lowest observed saturation, safe apnoea period, and Heart Rate (HR) trends, were also noted. Data were analysed using Statistical Package for Social Sciences (SPSS) version 20.0 and OpenEpi version 3.01. Results: Demographic and clinical parameters were comparable between the groups. The mean time for 1% desaturation was 18.33±4.3 seconds in Group-C, while all Group-O cases maintained 100% saturation during the study period. No significant difference was found in the safe apnoea period between the groups (p=0.503). The average lowest O2 saturation observed in Group-C was 98.81±1.28%, while it was 100% in Group-O. Only one infant in Group-C showed desaturation down to 95%. Both groups exhibited similar HR trends. Conclusion: Apnoeic oxygenation by nasal prongs in healthy infants helps prolong the time to desaturation and can be beneficial for those at risk of desaturation and hypoxia.
简介:新生儿和婴儿在喉镜和插管的呼吸暂停期更容易发生去饱和。除了传统的预充氧外,还有多种方法可以降低这种风险。目的:评价插管时通过鼻尖持续氧合与单纯预氧合的标准管理相比,是否能延长安全呼吸时间。材料与方法:2019年7月至2020年11月,在印度卡纳塔克邦巴拉里Vijayanagar医学科学研究所麻醉科进行了一项随机对照、两组平行临床研究。该研究涉及63名在全身麻醉下接受选择性或紧急手术的婴儿,年龄从1天到6个月不等。通过面罩进行预充氧,然后进行七氟醚诱导和维库隆诱导的肌肉松弛。c组(对照组)32例患儿行常规喉镜及气管插管,o组(窒息氧合组)31例患儿在预充氧的基础上,通过鼻尖钳以4l /min的速度吸氧。主要结局参数为1%去饱和所需时间。还记录了2%、3%、4%和5%去饱和所需的时间,以及它们的发生率、最低观察到的饱和度、安全呼吸暂停时间和心率(HR)趋势。使用SPSS 20.0版本和OpenEpi 3.01版本对数据进行分析。结果:两组间人口学和临床参数具有可比性。c组达到1%去饱和的平均时间为18.33±4.3秒,而o组在研究期间均保持100%饱和。两组间安全呼吸暂停时间差异无统计学意义(p=0.503)。c组平均最低氧饱和度为98.81±1.28%,o组最低氧饱和度为100%。c组只有一个婴儿的血饱和度降至95%。两组的人力资源趋势相似。结论:对健康婴儿进行鼻尖通气有助于延长去饱和时间,对有去饱和和缺氧危险的婴儿有益。
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引用次数: 0
Diffusion Tensor Imaging Parameters in Patients with Meningitis: A Case-control Study 弥散张量成像参数在脑膜炎患者中的应用:一项病例对照研究
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/65460.18391
Sargam Miglani, Shruti Chandak, Yogender ., Ankur Malhotra, Arjit Agarwal, Jigar Haria
Introduction: Neuroimaging plays an important role in the assessment of meningitis, but conventional Magnetic Resonance Imaging (MRI) is insensitive for early and specific diagnosis. Diffusion Tensor Imaging (DTI) can illustrate disturbances in white matter integrity before they become obvious on conventional MRI. Aim: To determine DTI parameters, specifically Fractional Anisotropy (FA) and Apparent Diffusion Coefficient (ADC), in patients with meningitis and compare them with controls. Materials and Methods: This case-control study was conducted over a period of 18 months at Teerthanker Mahaveer Medical College and Research Centre in Moradabad, Uttar Pradesh, India. The study included a total of 61 clinically diagnosed meningitis patients, aged 18 years and above, who were referred to the Department of Radiodiagnosis for an MRI Brain. Additionally, 61 controls were included. Conventional MRI images were obtained followed by DTI. FA and ADC values were calculated by placing Regions Of Interest (ROI) at different levels for both groups. DTI parameters for different causative organisms (bacterial, viral, tubercular, and fungal) were compared. Data was analysed using Statistical Package for the Social Sciences (SPSS) software version 24.0, and Analysis of Variance (ANOVA) test was used to identify significant differences. The p-value <0.05 was considered as statistically significant. Results: FA values were significantly lower in cases compared to controls at all levels in the brain (mean whole brain FA value of 0.30±0.036 in cases vs 0.43±0.030 in controls). ADC values were significantly higher in cases at the cerebellum, brainstem, and whole brain levels compared to controls (mean whole brain ADC value of 0.812±0.095 in cases vs 0.758±0.026 in controls) (p-value<0.05 considered statistically significant). These differences were evident in patients with clinically proven meningitis who had a normal appearance on conventional MRI, demonstrating the superiority of DTI over conventional MRI for the diagnosis of meningitis. Statistically significant differences were also found among different aetiological agents, highlighting the potential utility of DTI in the differential diagnosis of meningitis cases (mean whole brain FA of 0.31±0.038 in bacterial cases, 0.029±0.037 in viral cases, 0.299±0.034 in tubercular cases, and 0.27±0.00 in fungal cases vs. 0.43±0.030 in controls (p-value <0.01) and mean whole brain ADC values of 0.80±0.051 in bacterial, 0.85±0.14 in viral, 0.79±0.058 in tubercular, 1.03±0.00 in fungal cases vs. 0.758±0.026 in controls (p-value <0.01)). Conclusion: DTI is more sensitive than conventional MRI and is a useful early indicator of inflammatory process in patients with meningitis.
简介:神经影像学在评估脑膜炎中起着重要作用,但传统的磁共振成像(MRI)对早期和特异性诊断不敏感。弥散张量成像(Diffusion Tensor Imaging, DTI)可以在常规MRI显示白质完整性紊乱之前显示出来。目的:确定脑膜炎患者的DTI参数,特别是分数各向异性(FA)和表观扩散系数(ADC),并与对照组进行比较。材料和方法:本病例对照研究在印度北方邦莫拉达巴德的Teerthanker Mahaveer医学院和研究中心进行了为期18个月的研究。该研究包括61名临床诊断为脑膜炎的患者,年龄在18岁及以上,他们被转介到放射诊断部门进行MRI脑部检查。此外,还纳入了61名对照。常规MRI成像,DTI成像。通过将两组的感兴趣区域(ROI)置于不同的水平来计算FA和ADC值。比较不同病原菌(细菌、病毒、结核和真菌)的DTI参数。采用SPSS 24.0版社会科学统计软件包(Statistical Package for Social Sciences)对数据进行分析,采用方差分析(ANOVA)检验是否存在显著差异。p值<0.05认为有统计学意义。结果:与对照组相比,病例中脑内所有水平的FA值均显著降低(病例平均全脑FA值为0.30±0.036,对照组为0.43±0.030)。与对照组相比,小脑、脑干和全脑水平的ADC值显著升高(病例全脑ADC平均值为0.812±0.095,对照组为0.758±0.026)(p值0.05认为有统计学意义)。这些差异在临床证实的脑膜炎患者中很明显,这些患者在常规MRI上表现正常,表明DTI在诊断脑膜炎方面优于常规MRI。不同病因间的差异也有统计学意义,突出了DTI在脑膜炎病例鉴别诊断中的潜在应用价值(细菌性病例全脑平均FA为0.31±0.038,病毒性病例为0.029±0.037,结核病例为0.299±0.034,真菌病例为0.27±0.00,对照组为0.43±0.030 (p值<0.01);细菌性病例全脑平均ADC为0.80±0.051,病毒性病例为0.85±0.14,结核病例为0.79±0.058。真菌组为1.03±0.00,对照组为0.758±0.026 (p值<0.01)。结论:DTI比常规MRI更敏感,是脑膜炎患者炎症过程的一个有用的早期指标。
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引用次数: 0
Evaluating the Dietary Gaps and Anthropometric Parameters of the Government School Children Aged 11-14 Years in Accordance with ICMR Standards 根据ICMR标准评估11-14岁公立学校儿童的膳食缺口和人体测量参数
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/63452.18393
K Silambu Selvi, J Sai laavanya, G Nandhini, P Shanthini Priya, I Vanthi Ekal
Introduction: Malnutrition is a major global health crisis that needs immediate attention. Adolescence is a crucial stage where nutrition plays a major role on account of their growth and development. There is a need to assess the nutritional status of Government school children in Tamil nadu to take appropriate policy decisions and implement nutritional interventions. Aim: To assess the dietary gaps of Government school children and compare their anthropometric parameters with Indian Council of Medical Reasearch (ICMR) standards. Also, to associate their daily intake of five food groups with their weight status. Materials and Methods: This cross-sectional study was conducted by the Department of Clinical Nutrition and Dietetics, SRM Medical College Hospital and Research Centre (SRMIST), Kattankulathur, Chengalpattu District, Chennai,Tamil Nadu, India as a part of a nutritional awareness camp in month of March 2022 to examine the eating pattern of school-going children aged 11-14 years, in a Government school of Kalivanthapattu village, Chengalpattu, Tamil Nadu. Data was collected randomly among 73 school children during a nutritional awareness camp conducted by study Institute. A validated tool was used to identify the dietary gaps in food group intake and the anthropometric parameters were assessed using standard measures and were compared with ICMR and World Health Organisation (WHO) standards to analyse their nutritional status. The acquired data was analysed using Statistical Package for Social Sciences (SPSS) software. Results: Out of the 73 children, there were 52 girls and 21 boys and the mean age of the children was 12.09±0.80 years. The dietary gap assessment tool indicated the gross deficiency in the intake of different food groups by the children. The majority of the samples 52 (71.2%) had an average dietary pattern, 9 (12.3%) students were found to have poor dietary habits and only 12 (16.4%) students had a good dietary pattern. Body Mass Index (BMI) assessment indicated that 39 students (53.4%) were normal (-2SD to +1SD) and others were found to be malnourished. A substantial variation in the mean weight of 12-year-old-male students (p-value=0.025) as well as female students (p-value=0.003) was observed when compared to ICMR standards. There was high significant difference between mean height of 13-year-old female students and the mean height as per ICMR standards (p-value=0.004). Conclusion: The dietary intake of Government school children was average and the anthropemetric assessment indicated that many of them were malnourished.
导言:营养不良是一项需要立即关注的重大全球健康危机。青春期是一个关键阶段,营养对他们的生长发育起着重要作用。有必要评估泰米尔纳德邦公立学校儿童的营养状况,以便作出适当的政策决定并实施营养干预措施。目的:评估公立学校儿童的膳食差距,并将其人体测量参数与印度医学研究委员会(ICMR)标准进行比较。同时,将他们每天摄入的五种食物与体重状况联系起来。材料和方法:这项横断面研究是由印度泰米尔纳德邦金奈市昌加尔帕图区Kattankulathur SRM医学院医院和研究中心(SRMIST)临床营养和饮食学系进行的,作为营养意识训练营的一部分,于2022年3月在泰米尔纳德邦昌加尔帕图县Kalivanthapattu村一所政府学校检查11-14岁学龄儿童的饮食模式。数据是在研究所举办的营养意识夏令营中随机收集的。使用一种经过验证的工具来确定食物组摄入中的膳食差距,使用标准测量方法评估人体测量参数,并与ICMR和世界卫生组织(WHO)标准进行比较,以分析其营养状况。采用SPSS (Statistical Package for Social Sciences)软件对所得数据进行分析。结果:73例患儿中,女孩52例,男孩21例,平均年龄12.09±0.80岁。膳食差距评估工具显示了儿童在不同食物组摄入方面的总体不足。52名(71.2%)学生的饮食习惯一般,9名(12.3%)学生的饮食习惯较差,只有12名(16.4%)学生的饮食习惯良好。身体质量指数(BMI)评估显示39名(53.4%)学生正常(-2SD至+1SD),其余学生营养不良。与ICMR标准相比,观察到12岁男学生(p值=0.025)和女学生(p值=0.003)的平均体重发生了实质性变化。13岁女学生的平均身高与ICMR标准的平均身高有高度显著差异(p值=0.004)。结论:公学儿童膳食摄取量处于中等水平,人体测量结果显示存在营养不良。
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引用次数: 0
Prevalence of Different Attachment Styles in 9 to 12 years old School Children: A Cross-sectional Study 不同依恋类型在9 ~ 12岁学童中的流行:一项横断面研究
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/64693.18639
Supriya Thambireddy, SVSG Nirmala, Sivakumar Nuvvula
Introduction: Bowlby suggests that children develop internal working models in earlier stages depending on their attachment relationships with parents. In paediatric dental clinics, children tend to display various behaviours depending on their attachment style, which can affect the communication and treatment outcomes with the child dentist. Aim: To determine the prevalence of attachment styles in 9 to 12 years old school children and to assess the association of attachment styles with the age and gender of the children. Materials and Methods: A descriptive cross-sectional study was conducted on a total of 384 school children aged 9 to 12 years, in the Nellore district using the cluster sampling method. Attachment styles were measured using a 15-item questionnaire developed from the Attachment Questionnaire for Children (AQ-C). The children were instructed and then asked to read and rate the extent to which each questionnaire item described themselves. Data were analysed statistically using the chi-square test for prevalence of attachment styles, Pearson correlation, and multiple regression analysis for age and gender associations. The level of significance was set at p≤0.05. Results: The study found that 64.10% (n=246) of all participants exhibited a secure attachment style, while 7% (n=27) and 28.9% (n=111) displayed avoidant and ambivalent attachment styles, respectively. Age showed a significant association with secure (p=0.006) and ambivalent (p=0.026) attachment styles. However, gender did not show any association with attachment styles. Conclusion: The study concluded that the secure attachment style was the most prevalent, followed by ambivalent and avoidant attachment styles, regardless of gender. Age was found to be significantly associated with secure and ambivalent attachment styles.
Bowlby认为,儿童在早期阶段发展内部工作模式取决于他们与父母的依恋关系。在儿童牙科诊所,儿童往往表现出不同的行为取决于他们的依恋类型,这可能会影响与儿童牙医的沟通和治疗结果。目的:了解9 ~ 12岁学龄期儿童依恋类型的流行情况,并探讨依恋类型与儿童年龄、性别的关系。材料与方法:采用整群抽样方法,对Nellore区384名9 ~ 12岁学龄儿童进行描述性横断面研究。依恋类型采用从儿童依恋问卷(AQ-C)中开发的15项问卷进行测量。孩子们接受指导,然后被要求阅读并对每个问卷项目描述自己的程度进行评分。采用卡方检验对依恋类型的流行率进行统计分析,Pearson相关分析,并对年龄和性别相关性进行多元回归分析。p≤0.05为显著性水平。结果:64.10% (n=246)的被试表现为安全型依恋类型,7% (n=27)的被试表现为回避型依恋类型,28.9% (n=111)的被试表现为矛盾型依恋类型。年龄与安全型(p=0.006)和矛盾型(p=0.026)依恋类型有显著相关。然而,性别与依恋类型没有任何关联。结论:无论性别如何,安全型依恋类型最为普遍,其次是矛盾型和回避型依恋类型。年龄被发现与安全和矛盾的依恋类型显著相关。
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引用次数: 0
Comparison of Safety and Efficacy of Unilateral Spinal Anaesthesia and Ultrasound-guided Sciatic Femoral Nerve Block in below Knee Surgery: A Randomised Clinical Study 单侧脊髓麻醉与超声引导下坐骨股神经阻滞在膝下手术中的安全性和有效性比较:一项随机临床研究
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/64681.18653
Dhara M Shah, Bipin K Shah, Shruti Desai, Sarala C Baria
Introduction: With modern advances, Ultrasonography (USG)- guided regional block techniques have improved nerve blockade with lesser drug usage and maximum safety for patient care. The widely appreciated outpatient surgical care has compelled us to apply the fastest and safest anaesthesia technique. For lower limb surgeries, USG-guided Sciatic Femoral Nerve Block (SFNB) is an emerging alternative to Spinal Anaesthesia (SA). Aim: To compare the safety and efficacy of both techniques in terms of haemodynamic stability, quality of block, and postoperative analgesia. Materials and Methods: A randomised double-blind study conducted at GCS Medical College, Hospital, and Research Centre, Ahmedabad, Gujarat, India, on 80 patients aged 18 to 70 years of either sex, with American Society of Anaesthesiology (ASA) Grade 1 to 3, undergoing below-knee surgeries was divided into two groups. Group A received USA with 1.5 mL hyperbaric inj. ropivacaine 0.75%, and Group B received USGguided SFB with inj. ropivacaine 0.5% 30 mL (15 mL for sciatic nerve and 15 mL for femoral nerve block). Preparation Time (PT), Surgical Anaesthesia Time (SAT), haemodynamic changes, quality of block, Longevity of Anaesthesia (LoA), time of first rescue analgesia, time of spontaneous urination, readiness to discharge, and patient satisfaction were recorded. The statistical analysis was carried out using Statistical Package for Social Sciences version 23.0 (SPSS Inc., Chicago II, USA). The p-value was derived by unpaired t-test and Chi-square test. Results: PT and SAT were higher in Group B (12.10±2.02 mins and 15.74±1.58 mins) than in Group A (6.15±1.12 mins and 8.23±1.45 mins). LoA time and time to first rescue analgesic were higher in Group B (284.10±54.44 mins and 265.71±33.69 mins) than in Group A (138.75±23.30 mins and 132.40±17.41 mins). Time to first spontaneous urination and readiness to discharge were shorter in Group B (136.42±18.40 mins and 158.39±10.78 mins) than in Group A (162.20±26.54 mins and 181.53±18.18 mins). Haemodynamic stability was excellent in both groups with no significant fluctuation. Motor blockade of Bromage 3 grade was achieved in 40 and 38 patients in Group A and B, respectively. The development of VAS score >3 was faster in Group A than in Group B (35 versus 2) at the end of three hours. No adverse events were observed in any patient. Conclusion: USG-guided SFB offers a safe and efficient alternative to Unilateral SA (USA) with satisfactory blockage, stable haemodynamics, and better postoperative analgesia for below-knee surgeries.
简介:随着现代技术的进步,超声(USG)引导的区域阻滞技术改善了神经阻滞,减少了药物的使用,最大限度地提高了患者护理的安全性。广泛认可的门诊手术护理已迫使我们采用最快和最安全的麻醉技术。对于下肢手术,usg引导的坐骨股神经阻滞(SFNB)是一种新兴的替代脊髓麻醉(SA)。目的:比较两种技术在血流动力学稳定性、阻滞质量和术后镇痛方面的安全性和有效性。材料和方法:在印度古吉拉特邦艾哈迈达巴德的GCS医学院、医院和研究中心进行的一项随机双盲研究,将80名年龄在18至70岁之间、美国麻醉学会(ASA) 1至3级、接受膝盖以下手术的患者分为两组。A组给予USA + 1.5 mL高压静脉注射。罗哌卡因0.75%,B组注射USGguided SFB。罗哌卡因0.5% 30 mL(坐骨神经15 mL,股神经阻滞15 mL)。记录术前准备时间(PT)、手术麻醉时间(SAT)、血流动力学变化、阻滞质量、麻醉持续时间(LoA)、首次抢救镇痛时间、自主排尿时间、出院准备情况和患者满意度。统计分析使用statistical Package for Social Sciences version 23.0 (SPSS Inc., Chicago II, USA)进行。p值采用非配对t检验和卡方检验。结果:B组PT和SAT分别为12.10±2.02 min和15.74±1.58 min,高于A组(6.15±1.12 min和8.23±1.45 min)。B组患者首次抢救镇痛时间(284.10±54.44 min)和首次抢救镇痛时间(265.71±33.69 min)均高于A组(138.75±23.30 min和132.40±17.41 min)。B组首次自然排尿时间(136.42±18.40 min)和准备排尿时间(158.39±10.78 min)短于A组(162.20±26.54 min)和181.53±18.18 min。两组患者血流动力学稳定性良好,无明显波动。A组和B组分别有40例和38例患者达到Bromage 3级的运动阻断。3 h时,A组VAS评分>3的发展速度明显快于B组(35比2)。所有患者均未观察到不良事件。结论:usg引导下的SFB为单侧SA (USA)手术提供了一种安全有效的替代方法,具有满意的阻塞,稳定的血流动力学和更好的术后镇痛效果。
{"title":"Comparison of Safety and Efficacy of Unilateral Spinal Anaesthesia and Ultrasound-guided Sciatic Femoral Nerve Block in below Knee Surgery: A Randomised Clinical Study","authors":"Dhara M Shah, Bipin K Shah, Shruti Desai, Sarala C Baria","doi":"10.7860/jcdr/2023/64681.18653","DOIUrl":"https://doi.org/10.7860/jcdr/2023/64681.18653","url":null,"abstract":"Introduction: With modern advances, Ultrasonography (USG)- guided regional block techniques have improved nerve blockade with lesser drug usage and maximum safety for patient care. The widely appreciated outpatient surgical care has compelled us to apply the fastest and safest anaesthesia technique. For lower limb surgeries, USG-guided Sciatic Femoral Nerve Block (SFNB) is an emerging alternative to Spinal Anaesthesia (SA). Aim: To compare the safety and efficacy of both techniques in terms of haemodynamic stability, quality of block, and postoperative analgesia. Materials and Methods: A randomised double-blind study conducted at GCS Medical College, Hospital, and Research Centre, Ahmedabad, Gujarat, India, on 80 patients aged 18 to 70 years of either sex, with American Society of Anaesthesiology (ASA) Grade 1 to 3, undergoing below-knee surgeries was divided into two groups. Group A received USA with 1.5 mL hyperbaric inj. ropivacaine 0.75%, and Group B received USGguided SFB with inj. ropivacaine 0.5% 30 mL (15 mL for sciatic nerve and 15 mL for femoral nerve block). Preparation Time (PT), Surgical Anaesthesia Time (SAT), haemodynamic changes, quality of block, Longevity of Anaesthesia (LoA), time of first rescue analgesia, time of spontaneous urination, readiness to discharge, and patient satisfaction were recorded. The statistical analysis was carried out using Statistical Package for Social Sciences version 23.0 (SPSS Inc., Chicago II, USA). The p-value was derived by unpaired t-test and Chi-square test. Results: PT and SAT were higher in Group B (12.10±2.02 mins and 15.74±1.58 mins) than in Group A (6.15±1.12 mins and 8.23±1.45 mins). LoA time and time to first rescue analgesic were higher in Group B (284.10±54.44 mins and 265.71±33.69 mins) than in Group A (138.75±23.30 mins and 132.40±17.41 mins). Time to first spontaneous urination and readiness to discharge were shorter in Group B (136.42±18.40 mins and 158.39±10.78 mins) than in Group A (162.20±26.54 mins and 181.53±18.18 mins). Haemodynamic stability was excellent in both groups with no significant fluctuation. Motor blockade of Bromage 3 grade was achieved in 40 and 38 patients in Group A and B, respectively. The development of VAS score &gt;3 was faster in Group A than in Group B (35 versus 2) at the end of three hours. No adverse events were observed in any patient. Conclusion: USG-guided SFB offers a safe and efficient alternative to Unilateral SA (USA) with satisfactory blockage, stable haemodynamics, and better postoperative analgesia for below-knee surgeries.","PeriodicalId":15483,"journal":{"name":"JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135609941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of Endoscopic Ultrasound for the Detection of Asymptomatic Pancreatic Morphological Changes in Patients with Alcoholic Liver Disease: A Cross-sectional Study 超声内镜检测酒精性肝病患者无症状胰腺形态改变的有效性:一项横断面研究
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/65188.18396
Pankaj Gupta, Dinesh Agarwal, Anurag Govil, Harsh Udawat
Introduction: Although alcoholism is a common aetiological link between liver and pancreatic disorders, the frequency of coinciding pancreatic disease in patients with alcohol-related liver disease is not well understood. The present study mentions about the use of Endoscopic Ultrasound (EUS) with standardised criteria to assess asymptomatic or overt pancreatic pathology in patients with alcoholic liver disease. Aim: To determine the prevalence of asymptomatic Alcoholic Chronic Pancreatitis (ACP) in Indian patients affected by Alcoholic Liver Cirrhosis (ALC) using EUS. Materials and Methods: The present observational crosssectional study was conducted on patients attending the Outpatient Department of Gastroenterology at Santokba Durlabhji Memorial Hospital Cum Medical Research Institute, Jaipur, Rajasthan, India. A total of 35 patients were screened with alcoholic liver disease for pancreatic abnormalities using EUS. The patients were recruited for the study over a period of 12 months, from September 2013 to August 2014. The prevalence of chronic pancreatitis (CP) was determined, and abnormalities were graded according to the Rosemont criteria. The severity of alcoholic liver disease, as indexed by Child Pugh Scoring (CPS) and Model for End-stage Liver Disease (MELD), was evaluated for any association with endosonographic findings of CP. The influence of various clinico-demographic factors on alcoholic liver and pancreatic diseases was analysed using the PSS Inc. Chicago, IL program. Results: A total of 35 male patients, aged 28 to 65 years with a mean age of 46.97 years, fulfilled the inclusion criteria. EUS revealed a prevalence of CP in 20% of patients. Three patients showed changes suggestive of CP, of which two had ALC and one had Alcoholic Hepatitis (AH). Four patients were prioritised in categorised as indeterminate for CP, with three having cirrhosis and one having Alcoholic Fatty Liver (ALF). No significant influence of clinico-demographic profiles on the final outcome parameters was observed. The patient with endoscopic changes had a MELD score of 12.85±5.11 compared to patients without changes of ACP (19.1±5.71) (p=0.013). ALC was found to be inversely related to EUS changes of ACP. Conclusion: The EUS is an effective screening tool for evaluating pancreatic abnormalities in patients with alcoholic liver disease. The present study provides a comprehensive review of previous findings in light of the varying facts and figures. As there is still a lack of experimental animal models for ALC and ACP, studies of this kind may shed light on hidden links in disease pathology.
虽然酒精中毒是肝脏和胰腺疾病之间常见的病因学联系,但酒精相关性肝病患者并发胰腺疾病的频率尚不清楚。本研究提到了使用内镜超声(EUS)的标准化标准来评估酒精性肝病患者无症状或明显的胰腺病理。目的:用EUS测定印度酒精性肝硬化(ALC)患者无症状酒精性慢性胰腺炎(ACP)的患病率。材料与方法:本观察性横断面研究在印度拉贾斯坦邦斋浦尔Santokba Durlabhji纪念医院暨医学研究所消化科门诊就诊的患者中进行。共有35例酒精性肝病患者使用EUS筛查胰腺异常。从2013年9月到2014年8月,这些患者被招募参加为期12个月的研究。确定慢性胰腺炎(CP)的患病率,并根据Rosemont标准对异常进行分级。以儿童Pugh评分(CPS)和终末期肝病模型(MELD)为指标,评估酒精性肝病的严重程度是否与CP的超声检查结果有关。使用PSS Inc.分析了各种临床人口统计学因素对酒精性肝病和胰腺疾病的影响。芝加哥,伊利诺伊州项目。结果:35例男性患者符合纳入标准,年龄28 ~ 65岁,平均年龄46.97岁。EUS显示20%的患者有CP。3例患者表现出提示CP的变化,其中2例为ALC, 1例为酒精性肝炎(AH)。4名患者被优先归类为CP不确定,其中3名患有肝硬化,1名患有酒精性脂肪肝(ALF)。没有观察到临床人口学特征对最终结局参数的显著影响。内镜改变患者的MELD评分为12.85±5.11,而ACP未改变患者的MELD评分为19.1±5.71 (p=0.013)。ALC与EUS ACP变化呈负相关。结论:EUS是评估酒精性肝病患者胰腺异常的有效筛查工具。本研究根据不同的事实和数字,对以前的研究结果进行了全面的审查。由于目前还缺乏ALC和ACP的实验动物模型,这类研究可能会揭示疾病病理中隐藏的环节。
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引用次数: 0
A Rare Case of Tuberculosis in the Lumbar Facet Joint 腰椎小关节结核1例
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/62666.18400
Vijayanand Balasubramanian, Parth Mehta, Rajavel Kalirajan
Tuberculosis of the posterior elements is a rare and destructive form characterised by the destruction of the lamina, pedicle, or facet joints. Delay in clinical diagnosis and presentation is common because of poor visualisation of facet joints in X-rays. A 55-year-old male presented with back and left leg pain lasting for six months, accompanied by weakness in dorsiflexion of the left foot and ankle. Magnetic Resonance Imaging (MRI) revealed features suggestive of L4-L5 facetal arthritis on the left side, including marrow oedema, bone erosions, a posterior paraspinal abscess, and nerve root compression. The patient underwent posterior decompression and stabilisation, along with abscess drainage. The specimen was sent for histopathological examination, confirming the diagnosis of facetal joint tuberculosis. Antituberculous treatment was given for 12 months, that showed improved neurological status. This case is presented due to its rarity, highlighting the importance of considering facetal joint tuberculosis as a potential cause in cases of progressively increasing lower back pain, even in the absence of constitutional symptoms.
后椎体结核是一种罕见且具有破坏性的形式,其特征是椎板、椎弓根或关节突关节的破坏。临床诊断和表现的延迟是常见的,因为小关节在x光片上表现不佳。55岁男性,背部和左腿疼痛持续6个月,并伴有左脚和踝关节背屈无力。磁共振成像(MRI)显示左侧L4-L5面性关节炎的特征,包括骨髓水肿、骨糜烂、后棘旁脓肿和神经根受压。患者接受后路减压和稳定,同时进行脓肿引流。标本送组织病理学检查,确认诊断为面关节结核。给予12个月的抗结核治疗,显示神经系统状况有所改善。本病例因其罕见性而被提出,强调了即使在没有体质症状的情况下,在逐渐增加的下背部疼痛病例中,将面关节结核作为潜在原因考虑的重要性。
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引用次数: 0
Analysis of Postoperative Complications of Minimally Invasive Surgery for Carcinoma of Oesophagus: A Single Centre Retrospective Cohort Study 食管癌微创手术术后并发症分析:单中心回顾性队列研究
Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-01-01 DOI: 10.7860/jcdr/2023/65468.18472
Sonai Datta Kakati, Dokne Chintey, Gaurav Das, Marie Ninu
Introduction: Traditional transthoracic oesophagectomy is associated with high perioperative morbidity. Minimally Invasive Oesophagectomy (MIE) techniques have been shown to have a decreased incidence of respiratory complications and an improvement in perioperative outcomes, such as length of hospital stay and wound infection rates. Aim: To evaluate the incidence of postoperative respiratory complications, 30-day mortality, and length of hospital stay among patients with carcinoma of the oesophagus undergoing, VideoAssisted Thoracoscopic Surgery (VATS) oesophagectomy. Materials and Methods: A cross-sectional study was conducted in the Department of Anaesthesiology in a new thoracic oncology unit at a Tertiary Cancer care centre, Dr. B. Borooah Cancer Institute, Guwahati, Assam, India. A total of 67 patients with resectable oesophageal cancer who underwent VATS oesophagectomy from September 2019 to December 2021 were included. Patients who had surgery by open thoracotomy and inoperable cases were excluded. The patients’ clinicodemographic profile, intraand postoperative variables, and complications were studied. Descriptive statistics were used for analysis. A p-value ≤0.05 was considered statistically significant at a 5% level of significance. Results: Out of 67 patients, 45 (67.2%) were male, and 22 (32.8%) were female. The age ranged from 33 to 78 years with a median age of 55 years (IQR 47-61). The median body weight was 45 kg (IQR 42-53). Nineteen (28.4%) patients developed postoperative complications, including respiratory distress in 7 (10.4%) and anastomotic leakage in 5 (7.5%) patients. Other complications included symptomatic Coronavirus Disease 2019 (COVID-19) infection, pneumonia, mediastinitis, Multiorgan Dysfunction Syndrome (MODS) with sepsis, seizure and cardiac arrest, and surgical re-exploration. The 30-day mortality was 2.98%. The median length of hospital stay was 19 days (Interquantile Range (IQR) 16-22), which was higher in those with complications (p<0.001). One-lung ventilation was associated with a higher risk of postoperative respiratory complications (p=0.077). Conclusion: VATS oesophagectomy, even in a new thoracic oncology unit, was associated with lower perioperative complications, a shorter hospital length of stay, and decreased mortality compared to historical controls.
传统经胸食管切除术围手术期发病率高。微创食管切除术(MIE)技术已被证明可以降低呼吸系统并发症的发生率,并改善围手术期结果,如住院时间和伤口感染率。目的:评价食管癌行视频胸腔镜下食管切除术患者术后呼吸系统并发症的发生率、30天死亡率和住院时间。材料和方法:横断面研究是在印度阿萨姆邦Guwahati的B. Borooah博士癌症研究所三级癌症护理中心的新胸腔肿瘤科麻醉科进行的。在2019年9月至2021年12月期间,共有67例可切除食管癌患者接受了VATS食管癌切除术。经开胸手术者及不能手术者排除。研究患者的临床人口学特征、术中及术后变量和并发症。采用描述性统计进行分析。在5%的显著性水平上,p值≤0.05被认为具有统计学意义。结果:67例患者中,男性45例(67.2%),女性22例(32.8%)。年龄33 ~ 78岁,中位年龄55岁(IQR 47 ~ 61岁)。中位体重为45 kg (IQR 42-53)。术后并发症19例(28.4%),其中呼吸窘迫7例(10.4%),吻合口漏5例(7.5%)。其他并发症包括症状性2019冠状病毒病(COVID-19)感染、肺炎、纵隔炎、多器官功能障碍综合征(MODS)合并败血症、癫痫发作和心脏骤停以及手术再探查。30天死亡率为2.98%。中位住院时间为19天(分位差(IQR) 16-22),有并发症的患者住院时间更长(p < 0.001)。单肺通气与术后呼吸系统并发症的高风险相关(p=0.077)。结论:与历史对照相比,VATS食管切除术,即使是在一个新的胸部肿瘤单位,也与更低的围手术期并发症、更短的住院时间和更低的死亡率相关。
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