Comprehensive Reviews in Food Science and Food Safety最新文献

The widespread consumption of ultra-processed foods (UPFs) results from industrialization and globalization, with their elevated content of sugar, fat, salt, and additives, alongside the formation of dietary advanced glycation end products (AGEs), generating considerable health risks. These risks include an increased incidence of diabetes, cardiovascular diseases, and neurodegenerative disorders. This review explores the mechanisms of AGE formation in UPFs and evaluates emerging technologies and additives aimed at mitigating these risks. Both thermal methods (air frying, low-temperature vacuum heating, microwave heating, and infrared heating) and non-thermal techniques (high-pressure processing, pulsed electric fields, ultrasound, and cold plasma) are discussed for their potential in AGE reduction. Additionally, the review evaluates the efficacy of exogenous additives, including amino acids, polysaccharides, phenolic compounds, and nanomaterials, in inhibiting AGE formation, though results may vary depending on the specific additive and food matrix. The findings demonstrate the promise of these technologies and additives for reducing AGEs, potentially contributing to healthier food processing practices and the promotion of improved public health outcomes.

Biotechnology has significantly advanced the production of recombinant proteins (RPs). This review examines the latest advancements in protein production technologies, including CRISPR, genetic engineering, vector integration, and fermentation, and their implications for the food industry. This review delineates the merits and shortcomings of prevailing host systems for RP production, underscoring molecular and process strategies pivotal for amplifying yields and purity. It traverses the spectrum of RP applications, challenges, and burgeoning trends, highlighting the imperative of employing robust hosts and cutting-edge genetic engineering to secure high-quality, high-yield outputs while circumventing protein aggregation and ensuring correct folding for enhanced activity. Recombinant technology has paved the way for the food industry to produce alternative proteins like leghemoglobin and cytokines, along with enzyme preparations such as proteases and lipases, and to modify microbial pathways for synthesizing beneficial compounds, including pigments, terpenes, flavonoids, and functional sugars. However, scaling microbial production to industrial scales presents economic, efficiency, and environmental challenges that demand innovative solutions, including high-throughput screening and CRISPR/Cas9 systems, to bolster protein yield and quality. Although recombinant technology holds much promise, it must navigate high costs and scalability to satisfy the escalating global demand for RPs in therapeutics and food. The variability in ethical and regulatory hurdles across regions further complicates market acceptance, underscoring an urgent need for robust regulatory frameworks for genetically modified organisms. These frameworks are essential for safeguarding the production process, ensuring product safety, and upholding the efficacy of RPs in industrial applications.

Food safety is crucially linked to the food system, ensuring safe production, handling, and distribution to protect public health. Food allergy has been considered as a public health and food safety issue. Despite being widely regarded as a prevailing strategy for managing food allergies, strict food avoidance faces challenges due to allergen cross-contact in the food supply chain and the potential for inaccurate allergen labeling. Hence, a scientific approach to assess allergen risk in this context is imperative. In this review, a novel approach to managing food allergies, referred to as quantitative food allergen risk assessment, is presented. This discussion covered the evolving concepts and modern analytical approaches. Moreover, this review delves into the current application of quantitative food allergen risk assessment. Finally, a valuable tool for food allergen risk assessment in the food industry, Voluntary Incidental Trace Allergen Labelling (VITAL), was introduced. The establishment of a globally harmonized and standardized quantitative food allergen risk assessment framework could facilitate the promotion of international harmonization of allergen labeling, support food allergic consumers in making safe food choices, and safeguard the health of allergic individuals across various regions and ethnicities. The implementation of food allergen risk assessment could ensure both food supply chain safety and guide the establishment of acceptable allergen cross-contact levels, enhancing food safety and bolstering the integrity and sustainability of the food system.

Emulsion-based foods typically employ proteins as their stabilizers, and their quality maintenance mostly relies on freezing conditions. Currently, improving the freezing stability of food emulsions through various strategies has been a topical issue in food science fields, and the modification targeting proteins is an essential research direction. This review discusses the destabilization mechanisms of food emulsions during freezing, including changes in the aqueous and oil phases, lipid oxidation, changes in pH and ionic strength, and denaturation or inactivation of proteins as emulsifiers. Then, it illustrates the role of the spatial structural properties of proteins and the formation of interfacial protein films in maintaining the freezing stability of emulsions. Moreover, this review highlights the effects of protein modification strategies on the freezing stability of emulsions and emulsion gels, including enzymatic hydrolysis treatment, glycosylation, salt and pH treatment, polyphenol addition, and physical treatment. It also discusses the further application of protein-modified Pickering emulsions in the food industry. In summary, modification treatments performed on proteins are effective in improving the freezing stability of food emulsions, and this area still has considerable room for exploration in the future, such as treatments involving emerging technologies or emerging substances and the synergistic effect of different treatments in maintaining emulsion freezing stability. This review will provide valuable theoretical insights into the production of high-quality and shelf-stable emulsion-based food products.

There is an urgent need to address food safety concerns associated with multiple Maillard reaction‒derived chemical contaminants, such as acrylamide, heterocyclic aromatic amines, advanced glycation end products, and 5-hydroxymethylfurfural, which are present in processed foods. Current studies have focused on single contaminant generated by the Maillard reaction; however, there is a dearth of information regarding the interactions of multiple contaminants and their joint control methods. This review article comprehensively summarizes the state-of-the-art progress in the simultaneous analysis, coformation, joint hazardous control, and risk assessment of multiple food processing contaminants generated by the Maillard reaction. The Maillard reaction is associated with caramelization, lipid oxidation, protein oxidation, and ascorbic acid browning reactions. Mass spectrometry‒based chromatography is currently the preferred method for the simultaneous quantification of multiple contaminants, with metabolomics and indirect detection methodologies providing new insights. Mitigation strategies for multiple contaminants include optimizing pretreatment, introducing exogenous additives, regulating processing parameters, and utilizing emerging technologies. Limited animal studies on the metabolism of various contaminants have yielded diverse results, guided by biomarkers for deep understanding. Integrated risk assessment should be conducted to quantify multihazard health impacts. In future research, a unique framework should be developed for assessing multiple contaminants, characterizing their metabolic profiles, and optimizing control measures for Maillard reaction‒derived contaminants.

Pesticides production, consumption, and disposal around the world are raising concerns day by day for their human and environmental health impacts. Among developing treatment technologies, ozonation has attracted the attention of many researchers in recent years. It is an emerging and promising technology for removing pesticides in the aqueous environment and degrading the residual pesticides from the fruits and vegetables (F&V) surfaces. This systematic review presents an extensive study of the degradation of different types of residual pesticides from F&V using ozonation, micro- and nanobubble (MNB) ozonation, or other advanced techniques such as microwaves/ultrasonication and advanced oxidation process. This review compiles the studies that reported the effect of MNB size on the dissolution of ozone gas in the washing medium and its effect on the degradation of residual pesticides from F&V. The mechanism and routes of pesticide degradation and how integrating MNB technology (MNBT) can help overcome economic losses, reduce health issues for consumers, and save the environment from harmful chemicals used in the pesticides are also discussed. The article encourages the development and utilization of MNBT not only in agriculture, but aquaculture, fisheries, food industries, food storage, and packing, for reducing/degrading the residual pesticides from foods and support environmental sustainability as well as improve international trade.

In recent decades, frozen dough has become an attractive means of preserving and offering the convenience of fresh-tasting foods while retaining their nutritional benefits. However, the frozen dough industry still faces significant challenges related to processing, freezing, and storage that affect the dough's quality and stability during thawing. Understanding the complex interactions between proteins (gluten, glutenin, gliadin, and glutenin macropolymers), starch dynamics (gelatinization and retrogradation), and water distribution—particularly how ice crystals interact with the gluten–starch matrix—is essential for improving frozen dough quality. This review also delves into the rheological properties resulting from the interplay of these components, emphasizing their collective impact on dough texture and stability. Additionally, it explores various freezing mechanisms and innovative strategies to reduce freeze damage, as well as practical challenges in translating theoretical insights into industrial applications. Finally, it proposes future strategies for improving the shelf life and quality of frozen dough by optimizing freezing methods and water distribution. Through a comprehensive synthesis of current literature, this review underscores the critical importance of gluten–starch–water interactions in frozen dough and highlights promising strategies for enhancing product performance and quality.

Humans are exposed to a complex mixture of environmental and food-related chemicals throughout their lifetime. Exposome research intends to explore the nongenetic, that is, environmental causes of chronic disease and their interactions comprehensively. Residual antibiotics can enter the human body through therapeutics, foods of animal origin, aquatic products, or drinking water. In the last decade, significant levels of residual antibiotics in human urine have been described, demonstrating frequent exposure throughout populations. To which extent they contribute to human health risks is debated. Human biomonitoring (HBM) aims to determine and quantify concentrations of xenobiotics in human specimens and provides the toolbox to monitor exposure to diverse chemical exposures. Due to their public health implications, priority-listed xenobiotics are routinely monitored in the European Union and other countries. However, antibiotics, an important class of (food-derived) xenobiotics, are still not systematically investigated for a better and more holistic understanding in the context of exposomics. This review provides a comprehensive summary of HBM research related to antibiotics, existing liquid chromatography–mass spectrometry (LC–MS)-based analytical methods, and potential health risks caused by unintended exposure. Incorporating antibiotics into the chemical exposome framework through routine HBM using multiclass analytical methods will provide a better understanding of the toxicological or pharmacological mixture effects and, ultimately, the chemical exposome.

Spices and herbs are a crucial component of the global food industry, valued for their unique flavors, aromas, and bioactive properties. However, microbial contamination and quality degradation during production, storage, and distribution pose significant challenges. Ultraviolet (UV) and pulsed light (PL) processing have emerged as nonthermal technologies offering effective, eco-friendly solutions for microbial decontamination and quality retention in spices. This review explores recent advancements and applications of UV and PL treatments in the spice industry, highlighting their impact on pathogenic and spoilage microbial safety, physicochemical properties, and bioactive compound retention. UV processing, primarily involving UV-C radiation, inactivates microorganisms by disrupting DNA, offering effective surface decontamination without compromising quality of spices and herbs. PL, which utilizes high-intensity, broad-spectrum light pulses, extends this capability to irregularly shaped surfaces, further enhancing microbial inactivation. Both methods preserve key quality attributes such as phenolics, flavonoids, antioxidant activity, ascorbic acids, and color while mitigating sensory losses, making them attractive alternatives to conventional thermal and chemical treatments. The review also examines critical factors influencing the efficacy of these technologies, including processing parameters, spice morphology, and microbial load. Despite promising results, challenges related to regulatory approval, equipment design, and consumer acceptance remain. This comprehensive analysis underscores the potential of UV and PL technologies to revolutionize spices and herbs processing, ensuring safety and quality while aligning with sustainable and consumer-driven demands in the food industry.

Edible coatings are a combination of substances that are applied onto foods to enhance their shelf life and that can be consumed by humans. Coatings are often composed of a combination of proteins, lipids, and/or polysaccharides and can contain plasticizers to increase flexibility and elongation. Surfactants and emulsifiers are sometimes added to decrease surface water activity and prevent moisture loss. The ideal edible coating slows the loss of desirable flavor volatiles and water vapor as well as restricts the exchange of gases, creating a modified atmosphere but not creating anaerobic conditions, all while not adding off-flavors to the food. In this review, the different components used in edible films and coatings are examined, along with their benefits and weaknesses. Additionally, this study reviews possible safety issues associated with consuming ingredients used in edible films and coatings. Edible films and coatings are more successful when multiple ingredients are used together to create a good moisture and gas barrier, thus creating the possibility for interactions. Most, but not all, ingredients used in edible films and coatings do not pose a risk to people when consumed at the levels present in coatings. Thus, it is imperative to review and consider new data on the safety of ingredients used in coatings.