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Comparative Effect of Petroleum Products and Biomass Fuel Exposure on Serum Lipid profile and Atherogenic Indices of male Albino wistar Rats 石油产品和生物质燃料暴露对雄性白化wistar大鼠血脂和动脉粥样硬化指标的比较影响
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.21.11.628
Ude Tochukwu, M. Chukwuemeka, D. Emmanuel, Chikezie Onyebuchi Desmond, Awalu Chimezie Joseph, bekailo Sylvester Nnaemeka
The effects of petroleum products and biomass fuel on serum lipid profile and atherogenic indices were investigated in male wistar rats. Fifty adult male wistar rats were randomly assigned to five groups of ten animals each. Rats in group A served as control (exposed to fresh air). Group B, C, D and E were exposed to inhalation of kerosene, gasoline, liquefied petroleum gas and biomass smoke (wood smoke) respectively. All the exposures were done using whole body exposure chambers 70cm x 60cm x 60cm measurement for six weeks. Five millilitres of fasting blood sample were collected at the end of six weeks and used for analysis of lipid profile using mindray BS 120. Atherogenic indices were calculated using the appropriate formula. Values were analysed statistically using SPSS version 23.0. The result shows significant increase in the serum total, LDL, VLDL cholesterol and triglyceride concentrations of test groups relative to control (p<0.05), while inducing a significant decrease in HDL cholesterol though the effect appear to be more pronounced with kerosene exposure. The exposure also led to significant increase in CRR, AC and AIP (p<0.05). These results suggest that petroleum products and biomass fuel exposure could potentiate the risk of atherosclerosis through elicitation of dyslipidaemia.
研究了石油产品和生物质燃料对雄性wistar大鼠血脂及动脉粥样硬化指标的影响。50只成年雄性wistar大鼠随机分为5组,每组10只。A组为对照组(暴露于新鲜空气中)。B组、C组、D组和E组分别吸入煤油、汽油、液化石油气和生物质烟(木材烟)。所有暴露均采用全身暴露室70cm × 60cm × 60cm测量,持续6周。6周结束时采集5毫升空腹血,使用迈瑞bs120进行血脂分析。采用相应的公式计算动脉粥样硬化指数。采用SPSS 23.0版本对数值进行统计学分析。结果表明,与对照组相比,各试验组血清总胆固醇、低密度脂蛋白胆固醇、VLDL胆固醇和甘油三酯浓度显著升高(p<0.05),高密度脂蛋白胆固醇显著降低,但煤油暴露的影响更为明显。暴露也导致CRR、AC和AIP显著升高(p<0.05)。这些结果表明,石油产品和生物质燃料暴露可能通过引发血脂异常而增加动脉粥样硬化的风险。
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引用次数: 0
Editorial Highlights on Eco Toxicity and Nano Materials 生态毒性和纳米材料的社论重点
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.2021.S5.E001
E. Samuelson
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引用次数: 0
Ozone Layer Depletion and its Consequences on Humans:a Review 臭氧层损耗及其对人类的影响综述
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.21.11.627
S. Abdullah
Ozone (O3) is a stratospheric layer that assumes significant job in offering help to people for their endurance. It is a basic factor for some worldwide, natural and ecological wonders. The ultra-violet (UV) beams discharged from sun are caught by ozone and in this manner give a stable ontological structure in the biosphere. Different anthropogenic exercises, for example, emanations of CFCs, HCFCs and other organoincandescent lamp lead to the exhaustion of ozone. Ozone exhaustion is enabling the UV radiation to earth surface. The introduction to these radiations is seriously influencing all living things on earth, particularly the people. Perpetual or transitory visual deficiency, skin malignancy and insusceptibility concealment are the principle impacts of these radiations revealed by different scientists on people. The possibilities of ozone recuperation are as yet unfamiliar. The present circumstance of ozone portrayal requests dire healing measures to secure lives on this planet. Chlorofluorocarbons, halons and methyl bromide are largely critical ozone exhausting substances controlled under the Montreal Protocol. Satellite perception frameworks help to foresee future changes to the ozone layer. In view of understandings under the Montreal Protocol, the ozone layer is relied upon to recoup toward the center of the twenty first century. Research should be done to evaluate that how different alternatives of cooling agents (chlorofluorocarbons) tend to decrease the emission of chlorine.
臭氧(O3)是平流层中的一层,在帮助人们保持耐力方面起着重要的作用。它是一些世界范围内的自然和生态奇观的基本因素。太阳释放的紫外线被臭氧捕获,从而在生物圈中形成稳定的本体论结构。不同的人为活动,例如氯氟烃、氢氯氟烃和其他有机白炽灯的排放,导致臭氧耗竭。臭氧耗竭使紫外线辐射到地球表面。这些辐射的引入正在严重影响地球上的所有生物,特别是人类。不同的科学家揭示了这些辐射对人的主要影响,包括永久性或短暂性视力缺陷、皮肤恶性肿瘤和敏感性隐藏。臭氧恢复的可能性尚不为人所知。臭氧的现状要求采取可怕的治疗措施来保护这个星球上的生命。氯氟化碳、哈龙和甲基溴基本上是《蒙特利尔议定书》管制的关键臭氧消耗物质。卫星感知框架有助于预测臭氧层未来的变化。鉴于根据《蒙特利尔议定书》所达成的谅解,到21世纪中叶,依靠臭氧层来恢复。应进行研究,以评估不同的冷却剂(氟氯化碳)替代品如何减少氯的排放。
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引用次数: 0
Analysis of Physicochemical Parameters of Drinking Water in Samunaber and Piazza district, Gondar Town 贡达尔镇三堡及广场区饮用水理化参数分析
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.2021.S5.004
Bekele Gelagay, Sleshi Fente, A. Worku, Henok Birhanu
Physicochemical parameters; pH, Conductance (K), Total Dissolved Solid (TDS), Total Alkalinities (TA), Hardness, Chemical Oxygen Demand (COD), Dissolved Oxygen (DO), Sulphate (SO42-), Chloride (Cl-), Fluoride (F-), Lead (Pb) and Cadmium (Cd) were analyzed using standard analytical techniques. The mean values of physicochemical parameters in the town, higher values from the two districts are: pH (8.72 ± 0.15), Conductivity (362 μs ± 7.2 μs), Hardness (514 ppm ± 50.3 ppm as CaCO3), DO (5.2 ppm ± 0.35 ppm), TDS (1566 ppm ± 58 ppm), COD (531 ppm ± 8.1 ppm), SO4 3- (3.75 ppm ± 0.35 ppm), Cl- (162.1 ppm ± 2.0 ppm), F- (0.025 ppm ± 0.004 ppm), TA (30.0 ppm ± 1.2 ppm), Pb (0.130 ppm ± 0.010 ppm), Cd (0.0078 ppm ± 0.00035 ppm). The pH, Hardness, TDS, Pb and Cd higher values of the water samples analyzed in two districts of this study are not within the acceptable limits set by WHO for safe drinking water. However the maximum values of SO42-, Cl-, F-, TA, conductivity, analyzed in the two districts are within the maximum permissible level set by the WHO (World Health Organization) for safe drinking water.
物理化学参数;采用标准分析技术分析pH、电导率(K)、总溶解固形物(TDS)、总碱度(TA)、硬度、化学需氧量(COD)、溶解氧(DO)、硫酸盐(SO42-)、氯化物(Cl-)、氟化物(F-)、铅(Pb)和镉(Cd)。镇上的理化参数的平均值,高值两个地区是:pH值(8.72±0.15),电导率(362μs±7.2μs),硬度(514 ppm±50.3 ppm,碳酸钙),(5.2 ppm±0.35 ppm), TDS (1566 ppm±58 ppm),鳕鱼(531 ppm±8.1 ppm)、SO4 3 - (3.75 ppm±0.35 ppm)、Cl - (162.1 ppm±2.0 ppm), F - ppm(0.025±0.004 ppm),助教(30.0 ppm±1.2 ppm)、Pb (0.130 ppm±0.010 ppm), Cd (0.0078 ppm±0.00035 ppm)。本研究分析的两个地区的水样pH、硬度、TDS、Pb、Cd偏高值均不在WHO安全饮用水可接受范围内。然而,在这两个地区分析的SO42-、Cl-、F-、TA、电导率的最大值都在世界卫生组织规定的安全饮用水的最大允许水平之内。
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引用次数: 0
Geochemistry and Acute Toxicity in Rat of Calabash Clay Consumed in Douala (Cameroon) 喀麦隆杜阿拉地区食用葫芦泥对大鼠的地球化学及急性毒性
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.2021.11.632
Hermine Danielle Fouda Menye Ebana, Augustine Kuinze Nkojap, Y. Mapoure, S. Owona, Alain Bertr, Dongmo, M. SamuelHonore, engue
Background: Calabash chalk geophagia commonly consumed in Sub-Saharan countries such as Cameroon may be a source of potential harmful elements such as lead and mercury. We sought to determine its geochemical composition on representative sample collected in the central market of Douala and evaluate their acute toxicity profile using rat. Methods: The geochemical analysis of three prototypes of Calabash chalk samples collected in the Douala central market, their main place of supply in the town, has been performed using the X-ray Fluorescence (XRF) and the inductively Coupled Plasma-Mass Spectrometry (ICPMS) for major and trace elements respectively. Acute toxicity was assessed according to Organisation for Economic Cooperation and Development (OECD) guidelines test No 423. Results: The geochemistry displays the Al2O3 as their main major component with iron, titanium, cerium and zinc as metal and metalloid trace elements. No acute toxicity was found in rat after administration of 5000 mg/kg body weight. Conclusion: Calabash chalk belong to the kaolinite family which had showed evidence for digestive pharmacologic propriety. Their acute consumption may be less toxic while toxicity profile of chronic consumption should be investigated.
背景:喀麦隆等撒哈拉以南国家普遍食用的葫芦白垩食土可能是铅和汞等潜在有害元素的来源。我们试图在杜阿拉中心市场收集的代表性样品上测定其地球化学成分,并利用大鼠评价其急性毒性谱。方法:采用x射线荧光法(XRF)和电感耦合等离子体质谱法(ICPMS)对采自该镇主要供应地杜阿拉中心市场的3种葫芦白垩样品样品进行地球化学分析,测定其主量元素和微量元素。急性毒性根据经济合作与发展组织(OECD)第423号准则测试进行评估。结果:其主要成分为Al2O3,金属元素为铁、钛、铈、锌及类金属元素。给药5000mg /kg体重对大鼠无急性毒性作用。结论:葫芦白垩属高岭石科,具有消化药理作用。急性食用可能毒性较小,而慢性食用的毒性谱应加以研究。
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引用次数: 2
Permethrin and Cypermethrin Residues on Beans and Cucumber Plants Grown Under Greenhouse Conditions 温室条件下大豆和黄瓜的氯氰菊酯和氯氰菊酯残留量
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.21.11.630
G. Antonious
A simple, accurate, and cost-effective procedure for separation and quantification of two pyrethroid insecticides residues on bean and cucumber plants was achieved using a Gas Chromatograph (GC) equipped with an electron capture detector (GC-ECD) and GC equipped with a Mass Selective Detector (MSD). Following spraying fruits and leaves were collected to determine insecticides dissipation constants and half-lives (T1/2 values). Residues of the two pyrethroids revealed the presence of permethrin isomers at retention times of 26 and 26.6 min that correspond to the cis and trans-isomers, respectively. The GC also revealed the presence of four cypermethrin isomers at retention times of 30.3, 30.9, 31.3, and 31.5 min. The average initial deposits of permethrin were 2.7 and 0.2 on cucumber leaves and fruits surfaces, respectively. Whereas cypermethrin initial deposits were 5.1 and 2 μg g-1 on cucumber leaves and fruits, respectively indicating greater deposits on leaves than fruits. T1/2 values of permethrin and cypermethrin residues on beans pods (7.2 and 9.5 d, respectively) and cucumber fruits (13 and 3.3 d, respectively) indicated that a waiting period of 10 and 15 d are required for consumption of cucumber fruits and bean pods sprayed with cypermethrin at the recommended spraying dosage to drop the residues to the Maximum Residue Limits.
采用配备电子捕获检测器(GC- ecd)的气相色谱仪(GC)和配备质量选择检测器(MSD)的气相色谱仪(GC)实现了一种简单、准确、经济高效的分离和定量大豆和黄瓜两种拟除虫菊酯类杀虫剂残留的方法。喷洒后采集果实和叶片,测定杀虫剂的耗散常数和半衰期(T1/2值)。残留时间为26 min和26.6 min时,两种拟除虫菊酯的残留均存在氯菊酯的顺式异构体和反式异构体。在滞留时间分别为30.3、30.9、31.3和31.5 min时,氯氰菊酯在黄瓜叶片和果实表面的平均初始沉积量分别为2.7和0.2。而氯氰菊酯在黄瓜叶片和果实上的初始沉积量分别为5.1 μg -1和2 μg -1,表明叶片上的沉积量大于果实。氯氰菊酯和氯氰菊酯在豆荚(分别为7.2 d和9.5 d)和黄瓜果实(分别为13 d和3.3 d)上的残留T1/2值表明,按推荐用量喷洒氯氰菊酯的黄瓜果实和豆荚需要等待10 d和15 d,才能将残留降至最大残留限量。
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引用次数: 0
Clarification of Mechanisms of Reactive Oxygen Species Generation from Mitochondria 线粒体产生活性氧的机制澄清
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.2021.11.633
H. Indo, H. Ito, K. Nakagawa, H. Majima
It is known that reactive oxygen species (ROS) generated from mitochondria promote apoptosis. X-ray’s irradiation causes ROS generation from mitochondria and leads to apoptosis. We also published evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage. Recently, using human lung carcinoma cell lines A549 and H1299/wtp53, we demonstrated that 15.5 Gy monoenergetic X-ray irradiation of the K-shell resonance absorption peak of phosphorus results in increased mitochondrial ROS production.
众所周知,线粒体产生的活性氧(ROS)促进细胞凋亡。x射线照射引起线粒体产生ROS,导致细胞凋亡。我们也发表了在电子传递链受损和线粒体DNA损伤的细胞中线粒体产生ROS的证据。最近,我们利用人肺癌细胞系A549和H1299/wtp53,证明了15.5 Gy单能x射线照射磷的k -壳共振吸收峰导致线粒体ROS产生增加。
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引用次数: 0
Estimation of Heavy Metals and Polycyclic Aromatic Heavy Metals in Harvested Plantains from Bodo, Rivers State 河流州博多市收获大蕉中重金属和多环芳香族重金属的测定
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.2021.11.634
Eze Chukwuebuka Gabriel, I. Chukwudozie, Arazu, H. OparajiEmeka
A Plantain harvested from Bodo community, Gokana L.G.A Rivers state were analyzed for heavy metals and Polycyclic Aromatic Hydrocarbons (PAHs) concentrations. Physicochemical properties of the agricultural soil used for the plantain cultivation showed the following: pH (5.7) while the control experiment was seen at 7.4. Soil conductivity of 721 and 398 were obtained for both the test and control experiments, respectively. Soil mineral contents: Potassium (6.88 mg/g), phosphorus (2.63 mg/g), Magnesium (12.42 mg/g), chloride ions (1021.21 mg/g). Heavy metal analysis of the soil showed a greater proportion of copper and iron in while Hg, As and Cd were below detectable limit in both tested samples. Pb was found relatively in lower concentrations of 24.12 mg/g in the test sample, 6.23 mg/g in the control experiment. Total Oxidizable Carbon Content (TOC) and Total Petroleum Hydrocarbon (TPH) content of the soil were observed at 104.12 and 2567 mg/g respectively in the tested sample. The control experiment showed TOC and TPH concentrations of 42.85 and 1094 mg/g. Heavy metal analysis of harvested plantain from Bodoh community showed the presence of the following: Lead (Pb), Iron (Fe) and Copper (Cu) in the following order: Cu>Fe>Pb in the test sample while in the control experiment, iron (Fe) was seen greater than copper (Cu). Heavy metals of mercury, cadmium and arsenic were below detectable limit at in both the harvested plantain from Bodo community and those of the control experiment, respectively. Bioaccumulation factor of all the heavy metals identified were <1. PAHs of Acenaphthalene, Acenaphthene, chrysene, pyrene and fluranthene were not detected in the control experiment while only chrysene was not detected in the test samples. Naphthalene,methyl naphthalene, acenaphthalene, acenaphthene, benzo (k) fluranthene and flourene were relatively high in concentration than pyrene and flouranthene in the test samples. Naphthalene, methylnaphthalene, flourene and benzo(k) flouranthene were only recorded in the control experiment. Acenaphthalene (0.034 mg/g) was seen as the highest PAHs in bioaccumulation in the test sample while flourene (0.005 mg/g) recorded the highest in the control experiment.
分析了一株产自Gokana L.G.A Rivers州Bodo社区的大蕉的重金属和多环芳烃(PAHs)浓度。大蕉栽培用农业土壤的理化性质如下:pH值为5.7,而对照试验为7.4。试验和对照试验的土壤电导率分别为721和398。土壤矿物质含量:钾(6.88 mg/g)、磷(2.63 mg/g)、镁(12.42 mg/g)、氯离子(1021.21 mg/g)。土壤重金属分析表明,铜和铁的含量较高,而汞、砷和镉的含量均低于可检测限度。试验样品中Pb浓度相对较低,为24.12 mg/g,对照实验中为6.23 mg/g。土壤总氧化碳(TOC)含量为104.12 mg/g,总石油烃(TPH)含量为2567 mg/g。对照实验显示TOC和TPH浓度分别为42.85和1094 mg/g。对博多群落收获的车前草进行重金属分析,结果表明:铅(Pb)、铁(Fe)、铜(Cu)的含量依次为:Cu>Fe>Pb,而在对照试验中,铁(Fe)大于铜(Cu)。Bodo社区收获的车前草和对照试验收获的车前草中重金属汞、镉和砷均低于可检测限度。所有重金属的生物富集因子均<1。对照实验未检出苊、苊、蒽、芘和芴中的多环芳烃,而检测样品中仅检出了蒽。检测样品中萘、甲基萘、苊、苊、苯并(k)芴和芴的浓度相对高于芘和芴。对照实验中只记录了萘、甲基萘、芴和苯并(k)芴。试验样品中多环芳烃生物积累量最高的是苊(0.034 mg/g),对照实验中多环芳烃生物积累量最高的是芴(0.005 mg/g)。
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引用次数: 0
Lead and Zinc Concentrations in the Gill, Liver and Parasito-Fauna of Sarotherodon melanotheron iIn Makoko Lagoon, Lagos State, Nigeria 尼日利亚拉各斯州Makoko泻湖黑齿龙鳃、肝脏和寄生动物群中的铅和锌浓度
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.2021.11.631
O. Tola, A. Olakiigbe, J. Saliu
Morphometric and meristic features, metal accumulation and chemical composition of Sarotherodon melanotheron and its intestinal parasites were investigated in August, 2013. The Standard length of Sarotherodon melanotheron range between 13.10-21.50 cm with Mean ± SD of 16.15 ± 1.97, (p<0.001) and Head length range from 1.50-2.70 with Mean ± SD of 2.15 ± 0.28, (p<0.001). Heavy metal concentrations were determined in water, sediment, intestinal parasites, gills and liver of Sarotherodon melanotheron were analysed using Atomic Absorption Spectrophotometry to determine concentration of Pb and Zn. Metals in the water, sediment and parasites were above WHO level. The concentration of Lead and Zinc were higher in the sediment (Pb-18.82 and Zn-21.52) than the water (Pb-2.66 and Zn-15.41). The liver accumulated highest concentration of Lead and Zinc than the gill and parasite. The trend of lead accumulation was; gill (0.86)
2013年8月对黑素异齿沙罗齿(Sarotherodon melanotheron)及其肠道寄生虫的形态计量学、分分体特征、金属积累和化学成分进行了研究。标准长度为13.10 ~ 21.50 cm,平均±SD为16.15±1.97,(p<0.001);头长为1.50 ~ 2.70 cm,平均±SD为2.15±0.28,(p<0.001)。采用原子吸收分光光度法测定水体、沉积物、肠道寄生虫、鱼鳃和肝脏中的重金属含量。水中、沉积物和寄生虫中的金属含量高于世界卫生组织的水平。沉积物中铅和锌的浓度(Pb-18.82和Zn-21.52)高于水体(Pb-2.66和Zn-15.41)。肝脏累积的铅和锌浓度高于鳃和寄生虫。铅积累趋势为;鳃(0.86)<寄生(0.98)<肝脏(3.54)。这种积累在锌样品中也有类似的趋势,锌的平均浓度;寄生虫;(锌)(毫克/升);3.39, p<0.01,鳃;(锌)(毫克/升);肝脏0.72,p<0.01;(锌)(毫克/升);11.04, p < 0.01。鱼类寄生虫,特别是肠道棘头虫和绦虫,积累的重金属浓度明显高于鱼组织或环境中的浓度;因此,它们可以作为重金属污染的生物指标。重要的是继续监测马科泻湖水域、沉积物和鱼类中的重金属浓度,以便评估该地区重金属行为的趋势。
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引用次数: 0
Predicting Plant Communities in the Vicinity of Wheat Crops and Vineyards in Europe using Participatory Modeling 利用参与式模型预测欧洲小麦作物和葡萄园附近的植物群落
Pub Date : 2021-01-01 DOI: 10.37421/2161-0525.2021.S5.001
G. Arts, M. Eupen, S. Hennekens, P. Verweij
The risk assessment of pesticide use on non-target terrestrial plants is currently based on standardized greenhouse tests with a limited number of mostly crop plant species. Higher tier tests or assessments of any kind (e.g., field, semi-field, landscape studies) are not standardized. In this study we explored an approach to inform such a higher level by collecting datasets and information at European scale to characterize the vegetation communities that are likely to grow in the off-field areas of wheat and vine crops. The EUNIS (European Nature Information System) habitat classification was used to identify eight man-made habitats considered characteristic of the off-field areas in the European agricultural landscape. These habitats are spatially identified on the bases of a modelling process where vegetation plots, taken from the European Vegetation Archive, were used as observations and climate, soil, topographic, population density parameters and Remote Sensed Essential Biodiversity Variables as predictors. This modelling results in habitat suitability maps. The habitats are also described in terms of species frequencies and abundances, and to plant traits underlying possible vulnerability to pesticide exposure requested from the TRY plant trait database. Wheat and vine crop spatial data were derived from EUROSTAT and the QUICKScan methodology was used to combine all these data. We conclude that this method is helpful in reaching the objective as described in this paper. Its potential is that it can be extended probabilistically or linked to plant effect models.
目前,对非目标陆生植物使用农药的风险评估是基于标准化的温室试验,主要针对数量有限的作物植物物种。更高层次的测试或任何类型的评估(例如,实地、半实地、景观研究)都没有标准化。在这项研究中,我们探索了一种方法,通过收集欧洲规模的数据集和信息来描述可能在小麦和葡萄作物的场外地区生长的植被群落,从而为更高层次提供信息。欧洲自然信息系统(EUNIS)生境分类用于确定欧洲农业景观中被认为具有野外特征的八个人工生境。这些栖息地在空间上的识别是基于一个建模过程,该过程使用来自欧洲植被档案的植被样地作为观测数据,并使用气候、土壤、地形、人口密度参数和遥感基本生物多样性变量作为预测因子。这种建模的结果是生境适宜性图。根据物种频率和丰度以及TRY植物性状数据库中要求的可能易受农药暴露的植物性状,对生境进行了描述。小麦和葡萄作物的空间数据来自欧盟统计局,并使用QUICKScan方法将所有这些数据结合起来。我们得出结论,这种方法有助于达到本文所述的目标。它的潜力在于,它可以在概率上进行扩展,或者与植物效应模型相关联。
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引用次数: 0
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Journal of Environmental and Analytical Toxicology
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