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To Assess The Efficacy Of Two Regimens Of Misoprostol For Second Trimester Pregnancy Termination-A Randomized Comparison 评估米索前列醇两种方案在中期妊娠终止中的疗效——一项随机比较
Pub Date : 2009-12-31 DOI: 10.5580/2007
Rabia Kurshid, Abida Ahmed, S. Mir, I. Shamas
:We performed a randomized clinical trial in patients who were at 19-23 weeks gestation who were admitted for medical termination of pregnancy. All patients received 800 m gm of vaginal misoprostol and were assigned randomly to 400 m gm of oral misoprostol or 400 m gm of vaginal misoprostol every 8 hourly up to a maximum of 4 doses. Efficacy and side effects were compared. The mean induction abortion interval was compared in both groups.
我们对妊娠19-23周接受医学终止妊娠的患者进行了一项随机临床试验。所有患者均接受800 m gm阴道米索前列醇治疗,并随机分配至400 m gm口服米索前列醇或400 m gm阴道米索前列醇每8小时一次,最多4次剂量。比较两组的疗效和不良反应。比较两组平均引产时间。
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引用次数: 4
Theca lutein cyst rupture - an unusual cause of acute abdomen : a case report 叶黄素囊肿破裂-一个不寻常的急腹症的原因:1例报告
Pub Date : 2009-12-31 DOI: 10.5580/17f8
P. Dasari, K. Prabhu, T. Chitra
A 20 year old illiterate woman who had a spontaneous first trimester abortion followed by instrumental evacuation, presented 4 days later with sudden onset of pain and distension of abdomen along with difficulty in breathing. On examination, she was tachypnoeic, icteric with tachycardia. Abdominal examination revealed guarding and rigidity along with free fluid and vague mass in lower abdomen. Gynaecological examination showed purulent discharge through os with bogginess in all fornices. USG revealed echogenic fluid with bilateral large ovarian masses containing multiple small cysts. Laparotomy was performed with a provisional diagnosis of ruptured theca leutein cysts after 24 hrs of administration of broad spectrum antibiotics. There were bilateral theca leutein cysts of more than 10X15 cm, the left of which has ruptured and the right on the verge of rupture. Bilateral partial cystectomy was performed and histopathological examination confirmed theca lutein cysts with inflammatory infiltrate.
一名20岁文盲妇女,妊娠早期自然流产后进行器械排出术,4天后突然出现腹部疼痛和肿胀,并伴有呼吸困难。经检查,她呼吸急促,黄疸伴心动过速。腹部检查显示守卫和僵硬,下腹有游离液体和模糊的肿块。妇科检查显示脓性分泌物经输卵管排出,各脏器呈沼泽状。超声显示双侧卵巢大肿块伴多小囊肿。在给予广谱抗生素24小时后,进行剖腹手术,初步诊断为卵泡膜白蛋白囊肿破裂。双侧卵泡白蛋白囊肿大于10x15cm,左侧已破裂,右侧濒临破裂。行双侧部分膀胱切除术,组织病理学检查证实为叶黄素囊肿伴炎性浸润。
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引用次数: 0
Efficiency of intrauterine insemination as a method of treating marital infertility 宫内人工授精治疗夫妻不育症的效果
Pub Date : 2009-12-31 DOI: 10.5580/2e8
Fehmija Fetahovic, Zlatica Popivoda, D. Radonjić, D. Kljakić, G. Vukčević, S. Raičević
Introduction: Marital sterility is a special problem that the WHO declared as the disease and it is estimated that 15% of couples have been treated by this disease. The causes of marital infertility are 45-50%,of men, 45-50% of women and 5-10% couples of unknown causes. Total fertility rate in Montenegro has been reduced by about 10%. The aim of the study was to make the assessment of successfulness of intrauterine insemination, as one of the methods of treatment of marital infertility. Material and methods: We studied 27 infertile married couples, where 52 cycles were stimulated. In 42 (80.7%) of cycles the ovulation was confirmed and made intrauterine insemination (IUI) by husband's sperm, which was prepared by swim-up modified method. In 10 cycles there has been no adequate growth of follicles and the folliculigenesis stimulation was interrupted. The causes of infertility in the study group were: cause of male infertility (n = 11) mild and easy forms of endometriosis (n = 6) cervical factor (n = 4) and polycystic ovarian syndrome (n = 6). Results: The pregnancy occurred in 4 female patients. Percentage of pregnancy was 10.8%, compared to cycles in which ovulation was confirmed, after which intrauterine insemination was done. Percentage of pregnancy in married couples, according to the different causes of infertility was: infertility caused by cervical factor of 25%, the causes of male infertility 16.6%, with mild or easy endometriosis 18.2%, polycystic ovarian syndrome 16.6%. Discussion: Examination presents prospective study, which included 27 infertile couples, in which ovarian stimulation were performed with Clomifen citrate and made intrauterine insemination. In 18 pairs was about the secondary, and in 9 pairs, the primary infertility. We believe that our results are satisfactorily and consistent with published results in the reference literature. Conclusion: Intrauterine insemination is a cheap and minimally invasive method compared to other methods of assisted reproduction. Numerous reports indicate that the pregnancy rate is much higher if the IUI is combined with controlled ovarian stimulation.
简介:夫妻不育是世界卫生组织宣布为疾病的一个特殊问题,据估计,15%的夫妇曾接受过这种疾病的治疗。造成婚内不孕的原因有45-50%的男性、45-50%的女性和5-10%原因不明的夫妇。黑山的总生育率下降了约10%。本研究的目的是评估宫内人工授精作为治疗夫妻不孕症的方法之一的成功率。材料和方法:我们研究了27对不孕夫妇,其中52个周期被刺激。42个(80.7%)周期确认排卵,用丈夫精子进行宫内人工授精(IUI),采用游泳改良法制备。在10个周期内,卵泡没有充分生长,卵泡生成刺激被中断。研究组不孕原因为:男性不孕原因(n = 11)、轻易型子宫内膜异位症(n = 6)、宫颈因素(n = 4)、多囊卵巢综合征(n = 6)。结果:4例女性患者发生妊娠。与确认排卵后进行宫内人工授精的周期相比,妊娠率为10.8%。已婚夫妇怀孕的比例,按不孕原因的不同为:宫颈因素引起的不孕占25%,男性原因引起的不孕占16.6%,伴有轻度或易感性子宫内膜异位症占18.2%,多囊卵巢综合征占16.6%。讨论:前瞻性研究纳入27对不孕夫妇,应用枸橼酸氯米芬刺激卵巢并进行宫内人工授精。18对是继发性不孕,9对是原发性不孕。我们相信我们的结果是令人满意的,并且与参考文献中发表的结果一致。结论:与其他辅助生殖方法相比,宫内人工授精是一种经济、微创的辅助生殖方法。大量报告表明,如果宫内节育器与控制卵巢刺激相结合,怀孕率要高得多。
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引用次数: 0
Risk Analysis For The Birth Of A Small For Gestational Age (SGA) Infant 小于胎龄婴儿出生的风险分析
Pub Date : 2009-12-31 DOI: 10.5580/12fe
Masamitsu Nakamura, J. Hasegawa, Ryu Matsuaka, T. Mimura, K. Ichizuka, A. Sekizawa, T. Okai
Objectives: To investigate the possibility of the births of small for gestational age (SGA) infant in patients with risk factors.Methods: This study enrolled 3046 babies born between 2005 and 2007. The cases were divided into the small for gestational age (SGA) group (312 cases) and the control group (2734 cases). A multivariable analysis was conducted to retrospectively analyze the factors associated with low fetal birth weight, which include abnormalities of the neonate, placenta and umbilical cord, and maternal complications.Results: The odds ratios (99% confidence interval) of SGA were 5.3 (3.4-8.3) for multiple pregnancy, 2.4 (1.2-4.7) for fetal malformation, 4.6 (2.0-10.5) for velamentous cord insertion, 2.0 (1.0-3.8) for marginal cord insertion, 3.7(2.0-6.9) for hypercoiled cord, 5.3 (3.2-9.0) for pregnancy induced hypertension, and 1.8 (1.2-2.6) for low maternal body mass index (BMI<18.5). Conclusion: A multivariable analysis was conducted to determine the odds ratios for the birth of an SGA infant -for various risk factors of fetal growth restriction. These data might improve the prognosis of infants through the intensive perinatal management.
目的:探讨具有危险因素的小胎龄儿(SGA)出生的可能性。方法:本研究招募了2005年至2007年间出生的3046名婴儿。将病例分为小胎龄组(SGA) 312例和对照组(2734例)。通过多变量分析回顾性分析低出生体重的相关因素,包括新生儿、胎盘和脐带的异常以及母体并发症。结果:多胎妊娠SGA的优势比(99%置信区间)为5.3(3.4 ~ 8.3),胎儿畸形2.4(1.2 ~ 4.7),膜状脐带插入4.6(2.0 ~ 10.5),边缘脐带插入2.0(1.0 ~ 3.8),高卷脐带3.7(2.0 ~ 6.9),妊高征5.3(3.2 ~ 9.0),低母体体重指数(BMI<18.5)的优势比为1.8(1.2 ~ 2.6)。结论:我们进行了多变量分析,以确定SGA婴儿出生的优势比-胎儿生长受限的各种危险因素。这些数据可以通过加强围产儿管理来改善婴儿的预后。
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引用次数: 3
Premature Rupture Of Membranes At Week 19: Favorable Pregnancy Outcome And Four Years Follow-Up After Expectant Management 第19周胎膜早破:妊娠结局良好,随访4年
Pub Date : 2009-12-31 DOI: 10.5580/1856
T. A. Halima
Premature rupture of membrane (PROM) and preterm birth are the major public health problems accounting for mortality and morbidity both in infant and mother. Although, there are some reports available in world literature on PROM at week 20 and early preterm births prior to week 34, but most of these cases end in catastrophic outcome. In the present study a case report on PROM, associated with persistently marked oligohydramnios at week 19 is presented and discussed. The patient was managed expectantly and delivered at week 35 without any complication. Four years follow-up in pediatric clinics revealed a healthy normal child. Even though, the PROM was not anticipated – but its timely detection, prompt laboratory investigations, scrupulous patient care and meticulous management of infections, illness and hyperbilirubinemia lead to a favorable outcome. Subsequent care of the baby in the Neonatal Intensive Care Unit (NICU) and good oral feeding from day 1 appears to influence the normal progress of the baby.
胎膜早破(PROM)和早产是造成母婴死亡率和发病率的主要公共卫生问题。虽然,在世界文献中有一些关于20周胎膜早破和34周前早产的报道,但这些病例大多以灾难性的结局告终。在本研究的情况下,报告胎膜早破,与持续标记羊水过少在第19周提出和讨论。患者接受预期治疗,并于第35周分娩,无任何并发症。在儿科诊所进行了四年的随访,发现一个健康正常的孩子。尽管早膜早破是意料之外的,但它的及时发现、及时的实验室调查、细致的病人护理和对感染、疾病和高胆红素血症的细致管理导致了一个有利的结果。随后在新生儿重症监护病房(NICU)对婴儿的护理和从第一天开始良好的口服喂养似乎会影响婴儿的正常发育。
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引用次数: 2
Massive hemoperitoneum secondary to ruptured corpus luteum cyst of pregnancy in 17-year old female with Hemoglobin SC disease 伴有血红蛋白SC病的17岁女性妊娠黄体囊肿破裂继发大量腹膜出血
Pub Date : 2009-12-31 DOI: 10.5580/351
V. Andikyan, J. Ronald, Charles H. Bowers
We report a case of a 17 year old female with Hemoglobin SC (Hgb SC) disease and an early intrauterine pregnancy who sustained a significant hemoperitoneum secondary to a hemorrhagic corpus luteum cyst.A ruptured corpus luteum cyst presenting with significant hemoperitoneum is a rare but life threatening condition requiring immediate surgical intervention. It may occur both in the pregnant and non-pregnant state. If it occurs at an early gestational age the differential diagnosis between ectopic pregnancy and ruptured corpus luteum cyst of pregnancy can be extremely difficult.
我们报告一例17岁的女性血红蛋白SC (Hgb SC)疾病和早期宫内妊娠谁持续了显著的腹膜出血继发于出血性黄体囊肿。黄体囊肿破裂并伴有明显腹膜出血是一种罕见但危及生命的疾病,需要立即手术治疗。它可能发生在怀孕和非怀孕状态。如果它发生在妊娠早期,鉴别诊断异位妊娠和妊娠黄体囊肿破裂是非常困难的。
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引用次数: 5
Reopening Of A Previously Repaired Fistula Following Obstructed Labour: A Case Commentary 难产后先前修复的瘘管重新开放:一例评论
Pub Date : 2009-12-31 DOI: 10.5580/206c
A. Masinde, B. Gumodoka, H. B. Im
Background: Obstetric fistula is a common problem in Tanzania, with an incidence of about 1200 cases per year. Case: A 25 year-old female, para 2 with no living children, presented with a history of total urinary incontinence following a difficult vaginal delivery. Prior to this delivery she had a previous history of an obstructed labour complicated by vesico-vaginal fistula (VVF), for which she had had a caesarean section and then a vesical vaginal fistula repair in 2006. A repeat fistula was repaired successfully. Conclusion: Improvement in a patient’s socio-economic status and improvement to infrastructure would contribute greatly to prevention of obstetric fistula.
背景:产科瘘是坦桑尼亚的一个常见问题,每年的发病率约为1200例。病例:25岁女性,第2段,无在世子女,阴道分娩困难后出现尿失禁史。在此分娩之前,她曾有难产并发膀胱阴道瘘(VVF)的病史,为此她进行了剖腹产手术,并于2006年进行了膀胱阴道瘘修复手术。成功修复了重复瘘管。结论:提高患者的社会经济地位和改善基础设施将有助于预防产科瘘。
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引用次数: 0
Prevalence Of Sexually Transmitted Diseases In Pregnant And Non-Pregnant Women In Calabar, Cross River State, Nigeria. 尼日利亚克罗斯河州卡拉巴尔孕妇和非孕妇性传播疾病流行情况。
Pub Date : 2009-12-31 DOI: 10.5580/27f1
V. Usanga, L. Abia-Bassey, Pc Inyang-Etoh, F. Ani, E. Archibong
The prevalence of sexually transmitted diseases (STDs) in pregnant and non-pregnant women in Calabar was studied. Blood, high vaginal swabs (HVS) and Endocervical swab (ECS) samples were aseptically collected from five hundred and sixty two (562) antenatal pregnant women attending two tertiary hospitals in Calabar (the General Hospital and the University of Calabar Teaching Hospital ) and randomly from one hundred and eight (108) non-pregnant women in Calabar, and investigated for various etiologic agents of STDs including Neisseria gonorrhoeae, Candida albicans, Trichomonas vaginalis, Gardnerella vaginalis (Bacterial vaginosis), Treponema pallidum (Syphilis), Hepatitis B surface Antigen (HBsAg), Human immunodeficiency virus and Chlamydiae species, using standard microbiological methods. The HVS and the ECS swabs were analyzed using direct wet smear, Gram-stained smear and culture techniques while blood samples were examined serologically using standard proprietory reagents. Out of the 562 pregnant and 108 non-pregnant women examined, 250(44.5%) and 51(47.2%) were infected with various aetiologic agents respectively. In pregnant women, Candida albicans had the highest percentage of infections 121(21.5%) followed by HIV 38(6.8%) and Chlamydiae species 35(6.2%). Others were Hepatitis B surface antigen (HBsAg) 8(1.4%); Trichomonas vaginalis, 29(5.2%); Gardnerella vaginalis (Bacterial vaginosis), 12(2.1%) and Treponema pallidum (Syphilis) 7(1.2%). Neisseria gonorrhoeae was not isolated among the pregnant women. In non-pregnant women, Candida albicans also had the highest percentage of infections 23(21.3%) followed by Chlamydia species 11(10.2%) and HIV 9(8.3%). Others were Trichomonas vaginalis 4(3.7%); Hepatitis B surface antigen (HBsAg) 3(2.8) and Gardnerella vaginalis, 1(0.9). Neisseria gonorrhoeae and Treponema pallidum were not isolated. The prevalent rates of infections were inversely associated with increase in age and educational status. Increased pre/post conception screening for STDs is essential in preventing disease transmission and adverse pregnancy outcomes among these groups.
研究了卡拉巴尔市孕妇和非孕妇中性传播疾病的流行情况。对在卡拉巴尔市两所三级医院(综合医院和卡拉巴尔大学教学医院)就诊的562名(562名)产前孕妇和108名(108名)非孕妇进行无菌采集血液、阴道高拭子(HVS)和宫颈内拭子(ECS)样本,并对淋病奈瑟菌、白色念珠菌、阴道毛滴虫、阴道加德纳菌(细菌性阴道病),梅毒螺旋体(梅毒),乙型肝炎表面抗原(HBsAg),人类免疫缺陷病毒和衣原体物种,使用标准微生物方法。HVS和ECS拭子采用直接湿涂片、革兰氏染色涂片和培养技术进行分析,血样采用标准专有试剂进行血清学检测。在接受检查的562名孕妇和108名非孕妇中,分别有250名(44.5%)和51名(47.2%)感染了各种病原。在孕妇中,白色念珠菌的感染率最高,为121(21.5%),其次是HIV(38(6.8%))和衣原体(35(6.2%))。其他为乙型肝炎表面抗原(HBsAg) 8(1.4%);阴道毛滴虫29例(5.2%);阴道加德纳菌(细菌性阴道病)12例(2.1%),梅毒密螺旋体(梅毒)7例(1.2%)。孕妇中未分离到淋病奈瑟菌。在非孕妇中,白色念珠菌的感染率也最高23(21.3%),其次是衣原体11(10.2%)和HIV 9(8.3%)。阴道毛滴虫4(3.7%);乙型肝炎表面抗原(HBsAg) 3(2.8),阴道加德纳菌1(0.9)。淋病奈瑟菌和梅毒螺旋体未分离。流行感染率与年龄和教育程度的增加呈负相关。增加孕前/孕后性传播疾病筛查对于预防这些群体的疾病传播和不良妊娠结局至关重要。
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引用次数: 8
Sickle Cell Disease Complicated With Multiple Pregnancy: A Case Report 镰状细胞病合并多胎妊娠1例
Pub Date : 2009-12-31 DOI: 10.5580/2c2
A. Masinde, B. Gumodoka, H. B. Im
There is very little information available on how best to manage patient with multiple pregnancy and sickle cell disease. A Gravida2 Para1, 30 year-old female known patient with sickle cell disease, complicated with multiple pregnancy, and previous history of caesarean section, presented with anemia for which she was transfused. In the course of treatment she ruptured membranes, in view of this; a repeat caesarean section was performed. Operation was complicated with uterine atony and bleeding hence hysterectomy was done. Post-operative was unremarkable. Anemia is one of the major complications in a patient with sickle cell complicated with multiple gestation, hence prophylactic blood transfusion is recommended.
关于如何最好地管理多胎妊娠和镰状细胞病患者的信息很少。孕妇a2 Para1, 30岁女性,已知镰状细胞病,合并多胎妊娠,既往有剖腹产史,因贫血输血。因此,在治疗过程中,她的胎膜破裂了;再次进行了剖腹产手术。手术后并发子宫张力及出血,遂行子宫切除术。术后无明显变化。贫血是镰状细胞合并多胎妊娠患者的主要并发症之一,因此建议预防性输血。
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引用次数: 1
Hysterectomy: A Clinico-Pathological Correlation Of 500 Cases 子宫切除术:500例临床病理相关性分析
Pub Date : 2009-12-31 DOI: 10.5580/141b
G. Gupta, D. Kotasthane, V. D. Kotasthane
Hysterectomy is the most commonly performed gynaecological surgery throughout the world. Few studies have been performed describing the pathologic findings in hysterectomy specimens and examining the relationship between the pre-operative clinical indication and pathologic diagnosis. This study was undertaken to identify the most common pathologies identified in hysterectomy specimens and to correlate the findings with the clinical indications. Five hundred hysterectomy cases, over a period from April 2008 to March 2010 formed the subject for the present study. Ninety six percent of the hysterectomies were done for benign indications. Surgical specimens were formalin fixed and paraffin embedded. The sections were stained with routine hematoxylin and eosin stain. The most common pathology identified was leiomyoma followed by adenomyosis. Hysterectomies done for uterovaginal prolapse showed atrophic endometrium on histopathological examination. Other less frequent pathologies identified included endometrial hyperplasia, chronic endometritis and endometrial polyp. The pathologic examination confirmed the clinical diagnosis in all cases of leiomyoma, adenomyosis and endometrial polyps. This study confirms that benign pathologies are more common in hysterectomy specimens than their malignant counterparts. Histopathology is mandatory for mandatory for ensuring diagnosis and thus management, in particular of malignant disease.
子宫切除术是世界上最常见的妇科手术。很少有研究描述子宫切除术标本的病理表现,并探讨术前临床指征与病理诊断的关系。本研究旨在确定子宫切除术标本中最常见的病理,并将结果与临床适应症联系起来。本研究以2008年4月至2010年3月期间的500例子宫切除术病例为研究对象。96%的子宫切除术是出于良性指征。手术标本用福尔马林固定,石蜡包埋。切片用常规苏木精和伊红染色。最常见的病理是平滑肌瘤,其次是子宫腺肌症。子宫脱垂患者行子宫切除术,病理检查显示子宫内膜萎缩。其他不常见的病理包括子宫内膜增生、慢性子宫内膜炎和子宫内膜息肉。病理检查证实了所有病例的临床诊断为平滑肌瘤、子宫腺肌症和子宫内膜息肉。本研究证实良性病变在子宫切除术标本中比恶性病变更常见。组织病理学是强制性的,以确保诊断,从而管理,特别是恶性疾病。
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引用次数: 66
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The Internet journal of gynecology and obstetrics
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