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Post-vaccine immune status surveillance of Covishield vaccine and associated AEFI in previously SARS-Cov-2 infected seropositive and seronegative population in Assam 在阿萨姆邦曾感染过 SARS-Cov-2 的血清反应阳性和血清反应阴性人群中进行 Covishield 疫苗接种后免疫状态监测和相关 AEFI 监测
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_169_24
Gayatri Gogoi, Gourangie Gogoi, B. Mahanta, B. Borkakoty, Porikhit Borpujari, Tanzil S. Ahmed, Rahul Neog, Sunia Roy, Mithu Medhi
ABSTRACT COVID-19 an infectious disease caused by the SARS-CoV-2 virus, started in late 2019 and became a pandemic within a short period. To respond to the pandemic vaccines like Covishield, Covaxin, Sputnik V, Covovax, etc., were developed rapidly. However, there were raising concerns about the development of immunity as well as adverse events following vaccination. To compare anti-SARS-CoV-2 IgG antibody titres at different time-points post-vaccination between baseline seropositive and seronegative groups and to assess the adverse events following the 1st dose of Covishield vaccine among adult beneficiaries attending vaccination centre in a tertiary care hospital of Upper Assam. Prospective Cohort study was conducted from July 2021 to June 2022 among adult beneficiaries receiving the Covishield vaccine. The oral questionnaire was used incorporating socio-demographic variables, and clinical profiles including co-morbidities and adverse events following vaccination. Data analysis was done by Microsoft Excel and SPSS Out of a total of 146 study participants, IgG estimation showed 61% as seropositive and the rest as seronegative. A total of 55.40% had minor adverse events, majority of them were females (53.08%) and 88.80% belonged to 18–59 years compared to 11.11% above 60 years of age. The majority (71.60%) did not have any co-morbidities and the major AEFI was NIL among the study participants. The study group had 61% seropositive previously infected. Covishield vaccination induces an immune response and 90% seroconversion is achieved after 1st dose (booster dose). Antibody titres of the seropositive group by natural infection of SARS-CoV-2 were higher than seronegative cohort seroconverted by vaccination. The AEFI observed were minor and can be commented as safer.
ABSTRACT COVID-19 是一种由 SARS-CoV-2 病毒引起的传染病,始于 2019 年末,并在短期内成为大流行病。为了应对这一流行病,Covishield、Covaxin、Sputnik V、Covovax 等疫苗被迅速开发出来。然而,人们对疫苗接种后的免疫力发展和不良反应表示担忧。 目的:比较血清基线阳性组和血清阴性组在接种后不同时间点的抗 SARS-CoV-2 IgG 抗体滴度,并评估上阿萨姆邦一家三甲医院疫苗接种中心的成年受益者接种第一剂 Covishield 疫苗后的不良反应。 前瞻性队列研究于 2021 年 7 月至 2022 年 6 月期间在接种科维世盾疫苗的成人受益者中开展。研究采用口述问卷调查的方式,其中包括社会人口学变量、临床概况(包括并发症和接种疫苗后的不良反应)。数据分析由 Microsoft Excel 和 SPSS 完成。在总共 146 名研究参与者中,IgG 估计值显示 61% 为血清阳性,其余为血清阴性。55.40%的参与者出现了轻微的不良反应,其中大多数为女性(53.08%),88.80%的参与者年龄在18-59岁之间,60岁以上者仅占11.11%。大多数参与者(71.60%)没有任何并发症,主要的 AEFI 为无。研究组中有 61% 的既往感染者血清反应呈阳性。 Covishield 疫苗接种可诱导免疫反应,第一剂(加强剂)接种后可实现 90% 的血清转换。因自然感染 SARS-CoV-2 而血清反应呈阳性的人群的抗体滴度高于因接种疫苗而血清反应呈阴性的人群。观察到的 AEFI 不严重,可以认为比较安全。
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引用次数: 0
Public health preparedness, syndromic surveillance, and response during the largest religious gathering at the Catholic pilgrimage center of Velankanni in South India: 2016 南印度维兰卡尼天主教朝圣中心最大宗教集会期间的公共卫生准备、综合征监测和响应:2016 年
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_1815_23
M. Ponnaiah, Viduthalai Virumbi, Upasana Sharma, Sendhilkumar Muthappan, Ganeshkumar Parasuraman, Premkumar Balasubramanian, Vijayalakshmi Venkatachalam, Kolandaswamy Karumanagoundar
ABSTRACT The dynamicity and mobility of the population in a mass gathering setting pose a challenge to traditional disease surveillance methods and strain the local health services. Velankanni is one of the most sacred Christian pilgrimage places located in Nagapattinam, Tamil Nadu, India. We participated in the Velankanni festival to describe the public health preparedness, surveillance, and response activities carried out during the festival. This was a cross-sectional study. We reviewed the national and international guidelines and published literature and discussed with the key stakeholders. We developed a checklist to observe public health preparedness activities. We facilitated the staff and monitored the activities by the implementers. We established the syndromic surveillance in the designated locations of the event and used tracker software to capture the data. Emergency medical teams were formed with trained health personnel to respond to medical emergencies. The team monitored all the public health activities. There are 59 primary care public health facilities and nine ambulatory Mobile Medical Units, with 160 medical officers available at the site. Of the 16,169 persons who attended the medical camps, 9863 (61%) were males and 8408 (52%) were aged 15–44. Acute diarrheal disease was the most frequent of the reported syndromes, followed by injuries, acute febrile illness, and animal bites. There was no outbreak of any disease either identified or reported. Our findings suggest that risk assessments should be used, and establishing an Incident Command Center is vital for executing command and control mechanisms during mass gatherings.
摘要 在人群聚集的环境中,人口的动态性和流动性给传统的疾病监测方法带来了挑战,也给当地的医疗服务带来了压力。Velankanni 是位于印度泰米尔纳德邦 Nagapattinam 最神圣的基督教朝圣地之一。我们参加了维兰卡尼节,以描述节日期间开展的公共卫生准备、监测和应对活动。 这是一项横断面研究。我们查阅了国内和国际指南以及已发表的文献,并与主要利益相关者进行了讨论。我们制定了一份检查表来观察公共卫生准备活动。我们为工作人员提供便利,并监督执行人员的活动。我们在事件发生的指定地点建立了症候群监测系统,并使用跟踪软件采集数据。由训练有素的卫生人员组成紧急医疗队,以应对医疗紧急情况。 该小组负责监测所有公共卫生活动。共有 59 家初级保健公共卫生机构和 9 个流动流动医疗单位,160 名医务人员在现场提供服务。在参加医疗营的 16169 人中,9863 人(61%)为男性,8408 人(52%)年龄在 15-44 岁之间。在报告的综合症中,急性腹泻病最常见,其次是受伤、急性发热病和动物咬伤。 没有发现或报告任何疾病的爆发。我们的研究结果表明,应进行风险评估,建立事故指挥中心对于在大规模集会期间执行指挥和控制机制至关重要。
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引用次数: 0
Evaluation of a short-structured learner-centric training program on rational drug prescribing for medical interns: A quasi-experimental study 对以学习者为中心的实习医生合理用药短期培训项目的评估:准实验研究
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_129_24
A. Nishanthi, Rajalakshmi Mahendran, K. Ganapathy, M. Shanthi
ABSTRACT Rational drug prescribing skills of interns remain bleak despite clinical pharmacology training during their second year, warranting the need for further training. This study was designed to evaluate the effectiveness of a short-structured learner-centric training program using the World Health Organization (WHO) guide to good prescribing in improving interns’ knowledge of rational drug use and their rational drug prescribing skills. This quasi-experimental study was implemented at a tertiary care teaching hospital in South India. We conducted a short-structured learner-centric training program on rational drug prescribing for interns in September 2022, using the WHO guide to good prescribing. The medical interns who consented to participate were included in the study. A pre-test was administered at the start of the training, followed by a post-test and feedback questions at the end of the program. Statistical tests used for quantitative data were the Wilcoxon signed-ranks test and McNemar’s Chi-square test. Qualitative data were analyzed using manual content analysis. Of the 77 interns who attended the training program, 73 provided consent and completed both the pre-test and the post-test. Their mean age was 22 years, with a slight preponderance of female participants (53.4%). Overall, there was a statistically significant increase in the median (interquartile range) total scores from 52 (44.6 – 60) to 84 (70 – 88) after the training (P = 0.001), out of a maximum score of 93. Also, a significantly greater number of them wrote legible prescriptions (grade 4/excellent – 44 in pre-test vs 52 in post-test; P = 0.001) after the training. The short-structured learner-centric training program based on the WHO guide to good prescribing significantly improved the knowledge of rational drug use and rational drug prescribing skills among medical interns.
摘要 尽管实习生在第二年接受了临床药理学培训,但他们的合理用药处方技能仍然很差,因此需要进一步培训。本研究旨在评估采用世界卫生组织(WHO)良好处方指南开展的以学习者为中心的短期结构化培训项目在提高实习生合理用药知识和合理处方技能方面的效果。 这项准实验研究在印度南部的一家三级教学医院实施。2022 年 9 月,我们采用世界卫生组织的良好处方指南,为实习生开展了以学习者为中心的短期结构化合理用药培训项目。同意参与的医学实习生被纳入研究。培训开始时进行了前测,培训结束时进行了后测并提出了反馈问题。定量数据的统计检验采用 Wilcoxon 符号秩检验和 McNemar 的卡方检验。定性数据采用人工内容分析法进行分析。 在参加培训项目的 77 名实习生中,73 人同意并完成了前测和后测。他们的平均年龄为 22 岁,其中女性略占多数(53.4%)。总体而言,参加培训后,总分的中位数(四分位间距)从 52 分(44.6 - 60 分)提高到 84 分(70 - 88 分)(P = 0.001),其中最高分为 93 分。此外,培训后书写处方清晰可辨的人数也明显增加(4 级/优秀 - 测试前为 44 人,测试后为 52 人;P = 0.001)。 以世界卫生组织良好处方指南为基础、以学习者为中心的短期培训项目显著提高了实习医生的合理用药知识和合理处方技能。
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引用次数: 0
Yoga and nutritional therapies for promoting health-related quality of life in persons with metabolic syndrome—An interventional observational study 促进代谢综合征患者健康相关生活质量的瑜伽和营养疗法--一项干预性观察研究
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_1845_23
J. Sorout, S. Kacker, N. Saboo, Munesh Kumar
ABSTRACT A group of related risk factors known as central obesity, elevated blood pressure, impaired fasting glucose, elevated triglycerides (TGs), and low levels of high-density lipoprotein (HDL) are collectively referred to as metabolic syndrome (MetS). A low quality of life (QoL) in terms of health is linked to MetS. This study sought to determine how lifestyle modifications affected the health-related quality of life (HRQoL) of primary care patients with MetS. In this study, we randomized 300 subjects diagnosed with MetS as per the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria, into control, yoga, and yoga + diet groups according to their intervention which was given for 6 months. Socio-demographic, anthropometric, and physiological and biochemical parameters were collected at baseline, 3 months, and 6 months. The 36-Item Short Form Health Survey (SF-36) was also used to assess HRQoL. The results of this study indicate that yoga + diet and yoga intervention led to significant decrease in metabolic risk factors, such as waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), TGs, and increase in HDL at 3 months and 6 months from baseline. SF-36 score also showed increment (from 0 score to 100) at 3 months and 6 months, which indicates improvement in HRQoL. Dietary changes and yoga are useful strategies for reducing the risk of MetS, which improves QoL in relation to health. Incorporating yoga practices and advocating a balanced diet within primary care systems can significantly benefit individuals with or at risk of MetS.
摘要 中心性肥胖、血压升高、空腹血糖受损、甘油三酯(TGs)升高和高密度脂蛋白(HDL)水平低等一组相关风险因素统称为代谢综合征(MetS)。健康方面的低生活质量(QoL)与 MetS 有关。本研究旨在确定改变生活方式如何影响 MetS 初级保健患者的健康相关生活质量(HRQoL)。 在这项研究中,我们根据美国国家胆固醇教育计划成人治疗小组 III(NCEP ATP III)的标准,将 300 名被诊断为 MetS 的受试者随机分为对照组、瑜伽组和瑜伽+饮食组,根据他们的干预情况进行为期 6 个月的治疗。在基线、3 个月和 6 个月时收集社会人口学、人体测量、生理和生化参数。此外,还使用了 36 项简表健康调查(SF-36)来评估 HRQoL。 研究结果表明,"瑜伽+饮食 "和 "瑜伽 "干预能显著降低代谢风险因素,如腰围(WC)、收缩压(SBP)、舒张压(DBP)、空腹血糖(FBG)、总胆固醇(TGs),并在 3 个月和 6 个月时提高高密度脂蛋白(HDL)。SF-36 评分在 3 个月和 6 个月时也有增加(从 0 分到 100 分),这表明 HRQoL 有所改善。 饮食改变和瑜伽是降低 MetS 风险的有效策略,可改善与健康相关的 QoL。在初级保健系统中融入瑜伽练习并提倡均衡饮食,可使 MetS 患者或有 MetS 风险的人显著受益。
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引用次数: 0
A retrospective analysis of the trends in the prevalence of female genital mutilation and associated factors among women of reproductive age in Nigeria 2011–2021 2011-2021 年尼日利亚育龄妇女中切割女性生殖器流行趋势及相关因素的回顾性分析
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_1742_23
Felix O. Sanni, Elizabeth A. Sanni, Collins Onyeagwaibe, Tukwasi Ahamuefula
ABSTRACT Female genital mutilation (FGM) is widely acknowledged globally as a violation of the fundamental human rights of girls and women. FGM is still widely practiced in Nigeria but at diminishing rates. Primary care physicians must educate and campaign to end this hazardous practice in Nigeria, especially in high-incidence areas. This study fills the knowledge gap by identifying FGM determinants to help policymakers reduce it. The study employed a retrospective cross-sectional design using data from the United Nations International Children’s Emergency Fund for 2011, 2016–2017, and 2021. The sampling involved multistage cluster sampling. Data analysis utilized IBM-SPSS, presenting FGM prevalence across years and exploring associations with various factors. This study analyzed 63,365 Nigerian women across a decade (2011, 2016–2017, and 2021). FGM awareness fluctuated (35.1% in 2016–2017, 33.0% in 2011, and 31.9% in 2021), while FGM prevalence increased from 46.6% (2011) to 69.5% (2021). Education correlated with lower FGM prevalence. Geographic disparities were observed, with the Southwest having the highest (70.1%) and the Northeast having the lowest (34.5%) prevalence. Religion influenced FGM rates, with Christians (54.2%) and those with other/no religion (58.0%) showing higher rates than Muslims (52.6%). Urban women had a slightly lower prevalence (52.6%) than rural women (54.2%), and wealth quintiles displayed variations. Variability was also evident among states, ranging from 2.0% to 86.3%. Daughters’ circumcision was influenced by maternal circumcision status, education, region, religion, and wealth quintile. Common FGM procedures involved removing genital flesh (63.7%) and nicking without removal (55.1%), often performed by nurses/midwives (63.7%). The study emphasized the urgent need for continuous awareness campaigns and education to combat FGM among Nigerian women. Education emerged as a critical factor in reducing FGM, highlighting the importance of investing in girls’ education.
摘要 切割女性生殖器官(FGM)是全球公认的侵犯女童和妇女基本人权的行为。切割女性生殖器的做法在尼日利亚仍很普遍,但比例正在下降。初级保健医生必须开展教育和宣传活动,在尼日利亚(尤其是在高发地区)终止这种危险的做法。本研究通过确定女性外阴残割的决定因素来帮助决策者减少这种做法,从而填补了知识空白。 研究采用了回顾性横截面设计,使用了联合国国际儿童紧急基金 2011 年、2016-2017 年和 2021 年的数据。抽样涉及多阶段聚类抽样。数据分析采用了 IBM-SPSS,显示了女性外阴残割在不同年份的流行情况,并探讨了与各种因素的关联。 本研究分析了十年间(2011 年、2016-2017 年和 2021 年)63365 名尼日利亚妇女的情况。女性生殖器切割意识有所波动(2016-2017 年为 35.1%,2011 年为 33.0%,2021 年为 31.9%),而女性生殖器切割流行率从 46.6%(2011 年)上升到 69.5%(2021 年)。受教育程度与女性生殖器切割流行率较低有关。女性生殖器切割的流行率存在地域差异,西南部最高(70.1%),东北部最低(34.5%)。宗教对切割女性生殖器官的发生率有影响,基督教徒(54.2%)和其他/无宗教信仰者(58.0%)的发生率高于穆斯林(52.6%)。城市妇女的切割率(52.6%)略低于农村妇女(54.2%),财富五分位数之间也存在差异。各州之间的差异也很明显,从 2.0% 到 86.3% 不等。女儿的割礼受母亲割礼情况、教育程度、地区、宗教和财富五分位数的影响。常见的切割女性生殖器手术包括切除生殖器肉体(63.7%)和不切除生殖器肉体的切割(55.1%),通常由护士/助产士实施(63.7%)。 研究强调,迫切需要持续开展提高认识运动和教育,以打击在尼日利亚妇女中实施切割女性生殖器的行为。教育是减少切割女性生殖器官现象的一个关键因素,这凸显了投资女童教育的重要性。
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引用次数: 0
Impact of multidisciplinary management via special clinic for the outcome of diabetic foot disease: A prospective observational study 通过特殊诊所进行多学科管理对糖尿病足病治疗效果的影响:前瞻性观察研究
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_292_24
S. Meena, M. Badkur, M. Lodha, M. S. Rodha, Ramkaran Chaudhary, Naveen Sharma, Prakash C. Kala, Ravi Gaur, Sumit Bishnoi
ABSTRACT Diabetic foot is a common complication of diabetes mellitus, affecting approximately 15–20% of individuals with diabetes. It is a comorbid condition that significantly impacts the routine life of patients. This study aimed to assess multidisciplinary management strategies and their impact on the outcomes of patients with diabetic foot. A prospective observational study was conducted on 56 patients with diabetic foot. Outcome measures included the type of surgery, frequency of surgery, morbidity, mortality, patient satisfaction, return to work, and the number of patients using prostheses The majority of the patients (87%) received surgical treatment. The most common type of surgery performed was debridement (55%), followed by minor amputations (toes amputation/forefoot amputation) (28%) and major amputations (below-knee (B/K) or above-knee (A/K)) (15%). More than 70% of patients had multiple surgeries. The mortality rate was low (7%), and 71% of surviving patients were satisfied with their treatment. Sixty-seven percent of patients had an early return to work. The number of patients using prostheses was also high (73% of major amputation cases). Multidisciplinary management is the most effective approach for diabetic foot patients. These patients may experience less morbidity and an early return to work. A specialized care clinic for diabetic foot patients is essential to prevent treatment failure, loss of follow-up records, permanent limb loss, and economic burdens on society.
摘要 糖尿病足是糖尿病的一种常见并发症,约有 15-20% 的糖尿病患者会受到影响。它是一种并发症,严重影响患者的日常生活。本研究旨在评估多学科管理策略及其对糖尿病足患者治疗效果的影响。 研究对 56 名糖尿病足患者进行了前瞻性观察研究。结果测量包括手术类型、手术频率、发病率、死亡率、患者满意度、重返工作岗位以及使用假肢的患者人数。最常见的手术类型是清创(55%),其次是小截肢(脚趾截肢/前足截肢)(28%)和大截肢(膝下(B/K)或膝上(A/K))(15%)。70%以上的患者接受过多次手术。死亡率很低(7%),71%的存活患者对治疗感到满意。67%的患者可以尽早重返工作岗位。使用假肢的患者人数也很高(占大截肢病例的73%)。 对糖尿病足患者来说,多学科管理是最有效的方法。这些患者的发病率较低,并可早日重返工作岗位。糖尿病足患者专科护理诊所对于防止治疗失败、随访记录丢失、永久性肢体缺失以及社会经济负担至关重要。
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引用次数: 0
Dengue encephalitis – An unusual case series 登革热脑炎--一个不寻常的病例系列
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_413_24
Saniya Khosla, Rahul Chauhan, Ayush Aggarwal, Nupur B. Patel
ABSTRACT Dengue infection can take on many different forms, ranging from no symptoms to a mild fever, all the way to a severe condition known as dengue shock syndrome. Although the typical symptoms of dengue are well known, the virus can also cause rare neurological complications. Dengue encephalitis is a severe form of neuroinvasive dengue that can be fatal as the virus directly affects the central nervous system. This case series provides a comprehensive overview of dengue, its clinical spectrum, and the potential for severe neurological complications such as dengue encephalitis. It highlights the importance of considering dengue as a possible diagnosis in patients with encephalitis, particularly during a dengue epidemic.
ABSTRACT 登革热感染的形式多种多样,从无症状到轻微发烧,一直到被称为登革热休克综合征的严重病症。尽管登革热的典型症状众所周知,但该病毒还可引起罕见的神经系统并发症。登革脑炎是一种严重的神经侵袭性登革热,由于病毒直接影响中枢神经系统,因此可能致命。本系列病例全面概述了登革热、其临床表现以及引起登革脑炎等严重神经系统并发症的可能性。它强调了将登革热作为脑炎患者的可能诊断的重要性,尤其是在登革热流行期间。
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引用次数: 0
The association of continuous glucose monitoring with glycemic parameters in patients with uncontrolled type 2 diabetes: A prospective observational study 持续葡萄糖监测与血糖参数在未得到控制的 2 型糖尿病患者中的关联:前瞻性观察研究
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_1950_23
Abhishek Chaubey, Deepika Chaubey, Abhishek Dwivedi, Saurabh Dwivedi, Tanu Mishra
ABSTRACT Uncontrolled glycemic parameters in type 2 diabetes mellitus (T2DM) are a major concern. The present study aimed to evaluate the effectiveness of continuous glucose monitoring (CGM) on glycemic control in type 2 diabetics on insulin therapy. This prospective observational study was done in the Outpatient Department of General Medicine from January 1, 2021 till December 31, 2021 on patients with confirmed T2DM and on insulin therapy. Patients underwent detailed history and physical examination. The CGM device was inserted to record blood glucose levels throughout the day and night for monitoring. Parameters like glycosylated hemoglobin (HbA1c), fasting blood sugar (FBS), post-paradial blood sugar (PPBS), and lipid profile parameters [cholesterol, triglyceride (TG), and low-density lipoprotein (LDL)] were compared at baseline and after a follow-up of 3 months. P-value < 0.05 was used to indicate significant difference. Of 107 patients screened, 100 were included in the study and seven were excluded. The mean age of the patients was 60.6 ± 11.1 years. Fifty-six (56%) of the patients were males, and 44 (44%) were females. The mean body mass index (BMI) was 22.9 ± 2.4 kg/m2. Compared to baseline values, after 3 months of CGM, there was significantly decreased HbA1c (9.41 ± 0.83 vs 9.87 ± 1.16 g%, P < 0.001), FBS (194.640 ± 22.4587 vs 205.10 ± 35.7758 mg/dl, P = 0.002), PPBS (271.160 ± 29.1235 vs 299.180 ± 42.3798, P < 0.001), cholesterol (184.470 ± 28.5192 vs 198.430 ± 38.8367 mg/dl, P < 0.001), LDL (102.410 ± 22.8973 vs 112.040 ± 30.8859, P < 0.001), and TG (140.890 ± 18.0979 vs 146.730 ± 20.8665 mg/dl, P < 0.001). There was a significant improvement in the glycemic parameters and lipid profile parameters with the adoption of CGM. Overall, CGM is a novel method for practical use for management of patients with T2DM.
摘要 2 型糖尿病(T2DM)患者血糖参数失控是一个主要问题。本研究旨在评估持续葡萄糖监测(CGM)对接受胰岛素治疗的 2 型糖尿病患者血糖控制的效果。 这项前瞻性观察研究于 2021 年 1 月 1 日至 2021 年 12 月 31 日在全科门诊部进行,对象是确诊为 T2DM 并正在接受胰岛素治疗的患者。患者接受了详细的病史和体格检查。插入 CGM 设备,记录白天和晚上的血糖水平,以便进行监测。比较了基线时和随访 3 个月后的糖化血红蛋白(HbA1c)、空腹血糖(FBS)、paradial 后血糖(PPBS)和血脂谱参数[胆固醇、甘油三酯(TG)和低密度脂蛋白(LDL)]。P值小于0.05表示差异显著。 在接受筛查的 107 名患者中,100 人被纳入研究,7 人被排除在外。患者的平均年龄为(60.6 ± 11.1)岁。56名(56%)患者为男性,44名(44%)患者为女性。平均体重指数(BMI)为 22.9 ± 2.4 kg/m2。与基线值相比,使用 CGM 3 个月后,HbA1c(9.41 ± 0.83 vs 9.87 ± 1.16 g%,P < 0.001)、FBS(194.640 ± 22.4587 vs 205.10 ± 35.7758 mg/dl,P = 0.002)、PPBS(271.160 ± 29.1235 vs 299.180±42.3798,P<0.001)、胆固醇(184.470±28.5192 vs 198.430±38.8367 mg/dl,P<0.001)、低密度脂蛋白(102.410±22.8973 vs 112.040±30.8859,P<0.001)和总胆固醇(140.890±18.0979 vs 146.730±20.8665 mg/dl,P<0.001)。 采用 CGM 后,血糖指标和血脂指标均有明显改善。总之,CGM 是一种新型方法,可用于 T2DM 患者的实际管理。
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引用次数: 0
Knowledge and utilization of Integrated Child Development Services among antenatal women during COVID-19 pandemic COVID-19 大流行期间产前妇女对儿童综合发展服务的了解和利用情况
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_1803_23
Taniyaa Cruz Ferdina, Deepanchakravarthi Vellingiri, N. S. Raja, Gracy Paulin Dharmalingam
ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic has affected the healthcare delivery system in both developed and developing countries. Many antenatal women skipped their regular antenatal check-ups due to fear of viral contamination and lack of transport facilities. Integrated Child Development Services (ICDS), which plays a major role in antenatal care, also suffered a great deal during the pandemic. 1. To assess knowledge and utilization of ICDS services by antenatal women during the COVID-19 pandemic. 2. To determine factors influencing the knowledge and utilization of ICDS services by antenatal women. 3. To determine the barriers to utilization of ICDS services during the pandemic. This study was conducted as a descriptive study in a tertiary care center. Antenatal women whose pregnancy period coincided with the second wave of the COVID-19 pandemic were interviewed using a structured questionnaire. The sample size was calculated as 198. Data were entered in Microsoft Excel and analyzed using Statistical Package for Social Sciences (SPSS). Around 61% of the study population had adequate knowledge about ICDS services. The proportion of antenatal women utilizing ICDS services reduced from 87.8% to 69.6% during the pandemic. Only a few of the mothers were followed up by the Anganwadi workers during the pandemic. The main barriers to not utilizing ICDS services were fear of the spread of the pathogen and lack of awareness about the availability of services during the pandemic. There has been a reduction in the utilization of ICDS services by antenatal women during the COVID-19 pandemic. Measures should be taken by the government to ensure undisrupted care for antenatal women during such hard times.
ABSTRACT 2019 年冠状病毒病(COVID-19)大流行影响了发达国家和发展中国家的医疗保健系统。许多产前妇女因害怕病毒污染和缺乏交通设施而放弃了定期产前检查。在产前保健中发挥重要作用的儿童综合发展服务(ICDS)也在大流行期间遭受了巨大损失。 1.评估 COVID-19 大流行期间产前妇女对 ICDS 服务的了解和利用情况。2.确定影响产前妇女了解和利用 ICDS 服务的因素。3.确定大流行期间利用 ICDS 服务的障碍。 本研究是在一家三级护理中心进行的描述性研究。使用结构化问卷对孕期恰逢 COVID-19 第二波大流行的产前妇女进行了访谈。样本量计算为 198 人。数据输入 Microsoft Excel,并使用社会科学统计软件包(SPSS)进行分析。 约 61% 的研究对象对 ICDS 服务有足够的了解。大流行期间,利用综合儿童发展服务的产前妇女比例从 87.8%降至 69.6%。大流行期间,只有少数母亲得到了 Anganwadi 工作人员的跟踪服务。不利用综合儿童发展服务的主要障碍是害怕病原体传播和对大流行期间提供的服务缺乏了解。 在 COVID-19 大流行期间,产前妇女对 ICDS 服务的利用率有所下降。政府应采取措施,确保在这种困难时期对产前妇女的护理不中断。
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引用次数: 0
Vaginal tobacco – A hidden addiction in the African continent 阴道烟草--非洲大陆隐藏的烟瘾
IF 1.1 Q4 PRIMARY HEALTH CARE Pub Date : 2024-07-26 DOI: 10.4103/jfmpc.jfmpc_333_24
Shivashankar Kengadaran, Divvi Anusha
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引用次数: 0
期刊
Journal of Family Medicine and Primary Care
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