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Understanding menstrual health perceptions, practices, and premenstrual symptomatology among college girls in urban Chandigarh: A cross-sectional study. 了解昌迪加尔城市女大学生的月经健康观念、做法和经前症状:一项横断面研究
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_1064_25
Anuna Vinod, J S Thakur, Vineeth Rajagopal, Bushra Thasneem, P Karthika

Background: Menstruation is a natural physiological process, yet it continues to be surrounded by cultural silence and misconceptions in many communities. Poor menstrual hygiene and lack of awareness contribute to a range of health complications, including reproductive tract infections and psychosocial challenges. While studies on adolescent girls are common, research focusing on college-going young women aged 19-25 is relatively scarce.

Objective: To assess menstrual perceptions, practices, and awareness of premenstrual syndrome (PMS) among college students in Chandigarh, and to identify gaps in menstrual health knowledge and hygiene behavior.

Methods: A cross-sectional descriptive study was conducted among 100 female college students aged 19-25 years in Chandigarh using a pretested structured questionnaire. Data were analyzed using SPSS, with Chi-square tests applied to assess associations.

Results: Although 72% had premenarche knowledge and 98% used sanitary pads, only 33% changed them ≥ 4 times/day, and just 25% used soap and water for perineal hygiene. PMS awareness was low (52%), despite a high prevalence of related symptoms. Cultural restrictions were commonly reported, including food taboos and limited communication with male family members. A significant association was found between premenarche knowledge and menstrual hygiene practices (P = 0.022), and between perception and practice (P = 0.013). Overall, 78% had poor perception scores, and 82% practiced suboptimal hygiene.

背景:月经是一个自然的生理过程,但在许多社区,它仍然被文化沉默和误解所包围。月经卫生不良和缺乏认识会导致一系列健康并发症,包括生殖道感染和心理社会挑战。虽然对青春期女孩的研究很常见,但对19-25岁即将上大学的年轻女性的研究相对较少。目的:了解昌迪加尔市大学生对经前综合征(PMS)的认知、实践和意识,并确定其在月经健康知识和卫生行为方面的差距。方法:对昌迪加尔市100名年龄在19-25岁的女大学生采用预测式结构化问卷进行横断面描述性研究。数据分析采用SPSS,卡方检验评估相关性。结果:虽然72%的人有月经前期知识,98%的人使用卫生巾,但只有33%的人更换卫生巾≥4次/天,只有25%的人使用肥皂和水进行会阴卫生。尽管相关症状的患病率很高,但经前综合症的知晓率很低(52%)。普遍报道文化限制,包括食物禁忌和与男性家庭成员的有限交流。初潮前知识与经期卫生习惯之间存在显著相关性(P = 0.022),认知与实践之间存在显著相关性(P = 0.013)。总体而言,78%的人的感知得分较低,82%的人的卫生习惯不佳。
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引用次数: 0
Estimation of out-of-pocket expenditure and catastrophic health expenditure among households of urban areas of Haryana (India). 哈里亚纳邦城市地区家庭自付支出和灾难性卫生支出估算(印度)。
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_469_25
Ramesh Verma, Himani Arora, Meena Rajput, Meenakshi Kalhan, Vinod Chayal, Ginni Agrawal, Rohit Dhaka, Achchhesh Singmar, Divya Sharma, Meenu Yadav, Dwarka Nath, Amandeep Kaur, Mohit Rohilla, Amit Kumar, Pankul Parnami

Background: The health system financing of almost all low- and middle-income countries, including India, relies heavily on out-of-pocket (OOP) payments. Out-of-pocket expenditure (OOPE) for patient care has been known to cause maximum impoverishment. It can have debilitating consequences for the urban population or households. It is necessary to study patient care costs and the related factors among the households of an urban area to determine their vulnerability to catastrophic expenditure and to protect them from it.

Objective: The objective of the study is to estimate the out-of-pocket and catastrophic health expenditure in the urban population of Rohtak city, Haryana (India).

Methodology: This was a cross-sectional study conducted over a period of one year among urban households of District Rohtak, Haryana (India), who have been residing in the study area for at least one year. A sample size of 390 households was selected using simple random sampling. The study proforma as per the National Sample Survey Office (NSSO) was used to elicit and record relevant information.

Results: The majority, i.e., 81.8% of households, incurred OOPE while seeking treatment from health facilities. On multiple logistic regression analysis to identify significant determinants like medical insurance, age, chronic disease, duration of stay in hospital, and level of healthcare facility availed of net out-of-pocket (OOP) expenditure incurred on IPD treatment revealed no significant odds for incurring net out-of-pocket (OOP) expenditure (P > 0.05).

Conclusion: The majority of households in the study area incurred high OOP health expenditure and only 11.8% were having medical insurance, which highlights the need for active financial protection to bring down the OOP expenditure.

背景:包括印度在内的几乎所有低收入和中等收入国家的卫生系统资金严重依赖自付(OOP)。众所周知,病人护理的自付费用(OOPE)会导致最大程度的贫困。它可能对城市人口或家庭造成衰弱的后果。有必要研究城市家庭的患者护理费用及其相关因素,以确定其对灾难性支出的脆弱性,并保护他们免受其害。目的:本研究的目的是估计哈里亚纳邦(印度)罗塔克市城市人口的自付和灾难性卫生支出。方法:这是一项为期一年的横断面研究,研究对象是在印度哈里亚纳邦罗塔克区居住至少一年的城市家庭。采用简单随机抽样,样本量为390户。使用国家抽样调查办公室(NSSO)的研究形式来引出和记录相关信息。结果:大多数家庭,即81.8%的家庭,在向卫生机构寻求治疗时发生了OOPE。通过多元logistic回归分析,确定医疗保险、年龄、慢性病、住院时间和医疗机构水平等影响IPD治疗净自费(OOP)支出的重要因素,结果显示,发生净自费(OOP)支出的几率无显著差异(P < 0.05)。结论:研究区绝大多数家庭的整体健康支出较高,仅有11.8%的家庭拥有医疗保险,需要积极的财务保障来降低整体健康支出。
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引用次数: 0
Ayushman Arogya Mandir and India's progress toward Universal Health Coverage: A narrative review. Ayushman Arogya Mandir与印度在全民健康覆盖方面的进展:述评。
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_478_25
Srishti Gulati, Balu Natha Mote, Jatin Bhatt, Sudeshna Bandyopadhyay, Anantha Kumar Srinivasaiyer, Gurinder Bir Singh, Atul Kotwal

Ayushman Arogya Mandir (AAM) represents a watershed moment in the history of public health, marking a transformative step toward achieving Universal Health Coverage (UHC) in India. This manuscript provides a narrative review and secondary analysis of its impact, implementation challenges, and future potential. A narrative review was conducted in line with the Scale for the Assessment of Narrative Review Articles guidelines to enhance methodological transparency. A structured search was performed across PubMed, Scopus, and Google Scholar, complemented with official Government of India reports and policy documents. The search covered literature from January 2014 to November 2024 to capture developments before and after the launch of AAM in 2018. Search terms included combinations of "Ayushman Arogya Mandir," "Health and Wellness Centres," "Comprehensive Primary Health Care," "Universal Health Coverage India," "Ayushman Bharat," and "National Health Mission." A two-step screening process was followed: (i) titles and abstracts were screened to remove clearly irrelevant items, and (ii) full texts of potentially relevant articles and reports were assessed for inclusion. Peer-reviewed articles, government reports, and publicly available datasets relevant to India's UHC reforms were included, while commentaries without evidence, opinion pieces, were excluded. The analysis explores the initiative's alignment with global UHC principles and its role in enhancing equitable health access across diverse population segments, particularly marginalized communities. Significant paradigm shifts implemented after operationalization of AAM coupled with related health reforms have contributed to progress toward UHC by progressing its UHC Service Coverage Index from 57 in 2015 to 63 in 2021 (World Health Organization) and reduce the out of pocket expenditure from 60.6% in 2014-15 to 39.4% in 2021-22 (National Health Accounts estimates for India 2021-22). Though significant progress has been achieved, there persist challenges such as workforce shortages, infrastructural issues, and supply chain issues which require focused policy interventions. Despite the persisting challenges, AAM demonstrates significant promise as a scalable model for strengthening affordable, accessible, and quality primary healthcare, thereby contributing to India's progress toward UHC and offering lessons for other low- and middle-income countries.

Ayushman Arogya Mandir是公共卫生史上的一个分水岭,标志着印度朝着实现全民健康覆盖迈出了变革性的一步。这份手稿提供了对其影响、实施挑战和未来潜力的叙述性回顾和二次分析。为了提高方法的透明度,已按照叙述性审查文章评估比额表准则进行了叙述性审查。在PubMed、Scopus和谷歌Scholar上进行了结构化搜索,并辅以印度政府的官方报告和政策文件。该搜索涵盖了2014年1月至2024年11月的文献,以捕捉2018年AAM推出前后的发展。搜索词包括“Ayushman Arogya Mandir”、“健康和保健中心”、“综合初级卫生保健”、“全民健康覆盖印度”、“Ayushman Bharat”和“国家卫生使命”的组合。采用了两步筛选程序:(i)筛选标题和摘要,以删除明显不相关的项目;(ii)评估可能相关的文章和报告的全文,以便纳入。与印度全民健康覆盖改革相关的同行评议文章、政府报告和公开数据集被纳入,而没有证据的评论、观点文章被排除在外。分析探讨了该倡议与全球全民健康覆盖原则的一致性及其在促进不同人群,特别是边缘化社区公平获得卫生服务方面的作用。AAM实施后实施的重大模式转变,加上相关的卫生改革,促进了全民健康覆盖的进展,将全民健康覆盖服务覆盖指数从2015年的57提高到2021年的63(世界卫生组织),并将自付支出从2014-15年的60.6%降低到2021-22年的39.4%(印度2021-22年国民卫生账户估计)。尽管取得了重大进展,但仍然存在劳动力短缺、基础设施问题和供应链问题等挑战,需要有针对性的政策干预。尽管挑战依然存在,但AAM作为一种可扩展的模式,在加强可负担、可获得和高质量的初级卫生保健方面显示出巨大的希望,从而有助于印度在实现全民健康覆盖方面取得进展,并为其他低收入和中等收入国家提供经验教训。
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引用次数: 0
A comparative study of estimation of fetal weight in term pregnancy by clinical and sonographic method. 临床与超声法估计足月妊娠胎儿体重的比较研究。
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_796_25
Amrita Amrita, Jaya Kumari, Pratibha Biswas, Archana Sinha, Dipali Prasad, Pushpa Pushpa

Background: Birth weight is the critical determinant of neonatal survival, with deviations from the norm increasing the risks of perinatal morbidity and mortality. Accurate estimation of fetal weight is essential for effective management during labor, particularly in high-risk pregnancies. Clinical and sonographic methods are the primary techniques for estimating fetal weight, with each method showing distinct advantages and limitations.

Objective: This study aims to compare the accuracy of clinical (Insler's formula) and sonographic (Hadlock's formula) methods in estimating fetal weight, by correlating these estimates with actual birth weight.

Materials and methods: A prospective observational study was conducted, including 100 antenatal cases with term singleton pregnancies. Clinical assessments were performed using Insler's formula, while ultrasound-based fetal weight estimation was done using Hadlock's formula. Birth weight was recorded post-delivery, and statistical analysis was performed to assess correlations and agreement.

Results: The mean fetal weight estimated by Insler's formula was 3.23 ± 0.42 kg, and by Hadlock's formula was 3.16 ± 0.44 kg. The actual birth weight averaged 3.06 ± 0.42 kg. Both methods showed fair agreement with actual birth weight, with Cohen's kappa values of 0.274 (Insler's) and 0.167 (Hadlock's), indicating statistically significant agreement in the Insler's formula group (P < 0.001) but not in the Hadlock's formula group (P = 0.089).

Conclusion: Both clinical and sonographic methods demonstrate fair agreement with actual birth weight, but clinical method (Insler's formula) is more accessible, cost-effective, and accurate for fetal weight estimation in low-resource settings. This study suggests that clinical methods can be reliably used in managing labor and delivery in resource-limited environments.

背景:出生体重是新生儿生存的关键决定因素,与标准偏差增加围产期发病率和死亡率的风险。准确估计胎儿体重对于分娩期间的有效管理至关重要,特别是在高危妊娠中。临床和超声方法是估计胎儿体重的主要技术,每种方法都有其独特的优点和局限性。目的:本研究旨在比较临床(Insler公式)和超声(Hadlock公式)估算胎儿体重的准确性,并将这些估计值与实际出生体重相关联。材料与方法:对100例足月单胎妊娠孕妇进行前瞻性观察研究。临床评估采用Insler公式,而基于超声的胎儿体重估计采用Hadlock公式。分娩后记录出生体重,并进行统计分析以评估相关性和一致性。结果:Insler公式计算的胎儿平均体重为3.23±0.42 kg, Hadlock公式计算的胎儿平均体重为3.16±0.44 kg。实际出生体重平均为3.06±0.42 kg。两种方法均与实际出生体重相符,Cohen's kappa值分别为0.274 (Insler's)和0.167 (Hadlock's),表明Insler's配方奶组的差异具有统计学意义(P < 0.001),而Hadlock's配方奶组的差异无统计学意义(P = 0.089)。结论:临床方法和超声检查方法均与实际出生体重相符,但临床方法(Insler公式)更容易获得,成本效益高,在资源匮乏的情况下胎儿体重估计更准确。本研究提示临床方法可以可靠地用于资源有限环境下的分娩管理。
{"title":"A comparative study of estimation of fetal weight in term pregnancy by clinical and sonographic method.","authors":"Amrita Amrita, Jaya Kumari, Pratibha Biswas, Archana Sinha, Dipali Prasad, Pushpa Pushpa","doi":"10.4103/jfmpc.jfmpc_796_25","DOIUrl":"https://doi.org/10.4103/jfmpc.jfmpc_796_25","url":null,"abstract":"<p><strong>Background: </strong>Birth weight is the critical determinant of neonatal survival, with deviations from the norm increasing the risks of perinatal morbidity and mortality. Accurate estimation of fetal weight is essential for effective management during labor, particularly in high-risk pregnancies. Clinical and sonographic methods are the primary techniques for estimating fetal weight, with each method showing distinct advantages and limitations.</p><p><strong>Objective: </strong>This study aims to compare the accuracy of clinical (Insler's formula) and sonographic (Hadlock's formula) methods in estimating fetal weight, by correlating these estimates with actual birth weight.</p><p><strong>Materials and methods: </strong>A prospective observational study was conducted, including 100 antenatal cases with term singleton pregnancies. Clinical assessments were performed using Insler's formula, while ultrasound-based fetal weight estimation was done using Hadlock's formula. Birth weight was recorded post-delivery, and statistical analysis was performed to assess correlations and agreement.</p><p><strong>Results: </strong>The mean fetal weight estimated by Insler's formula was 3.23 ± 0.42 kg, and by Hadlock's formula was 3.16 ± 0.44 kg. The actual birth weight averaged 3.06 ± 0.42 kg. Both methods showed fair agreement with actual birth weight, with Cohen's kappa values of 0.274 (Insler's) and 0.167 (Hadlock's), indicating statistically significant agreement in the Insler's formula group (<i>P</i> < 0.001) but not in the Hadlock's formula group (<i>P</i> = 0.089).</p><p><strong>Conclusion: </strong>Both clinical and sonographic methods demonstrate fair agreement with actual birth weight, but clinical method (Insler's formula) is more accessible, cost-effective, and accurate for fetal weight estimation in low-resource settings. This study suggests that clinical methods can be reliably used in managing labor and delivery in resource-limited environments.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 1","pages":"386-390"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12975061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A randomized control trial comparing the clinical outcome of thyroxine supplementation in thyroid peroxide antibody- negative cases in patients with subclinical hypothyroidism in pregnancy. 一项比较甲状腺过氧化物抗体阴性妊娠期亚临床甲状腺功能减退患者补充甲状腺素的临床结局的随机对照试验。
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_1874_24
Mukta Agarwal, Shivangni Sinha, Divenndu Bhushan, Ishita Roy, Simran Simran
<p><strong>Background: </strong>A normal free thyroxine level in the presence of an increased thyroid-stimulating hormone is what constitutes subclinical hypothyroidism (TSH). Changes in thyroid physiology during pregnancy result in the normal TSH range being lower than non-pregnant. Subclinical thyroid disease during pregnancy is associated with adverse outcomes, including, risk of adverse pregnancy and neonatal outcomes. Prevalence in India is 6-8%. The prevalence of antibodies varies with ethnicity. Pregnancy with TSH concentrations >2.5 mIU/L needs evaluation for thyroid peroxidase antibody (TPO) antibody status. Literature and guidelines support Thyroxine supplementation in TPO antibody-positive patients and TPO-negative with TSH >10 mIU/L. However, there are numerous debates around pregnant individuals with TPO antibody negative and TSH <10 mIU/L.</p><p><strong>Objective: </strong>To determine the effect of thyroxine supplementation in pregnant women with TPO antibody-negative subclinical hypothyroidism. It is a prospective randomized control study conducted in the tertiary care institute of eastern India. In this trial, a TSH estimation of all pregnant women visiting the OPD of a tertiary care institute was performed. TSH values >2.5 are subjected to TPO antibody estimation. Patients with TSH value 2.5-5.0 mIU/L and TPO antibody negative were included. A total of 60 cases were included, randomized into two groups (Group A and B). Group A-thyroxine supplemented, Group B-placebo (folic acid). Thyroid levels are measured at intervals. Followed up for pregnancy, delivery, and neonatal complications. We studied the following outcomes: 1. Pregnancy-related complications - Gestational hypertension, gestational diabetes mellitus, and intrahepatic cholestasis of pregnancy (IHCP), intra-uterine growth retardation (IUGR), Antepartum hemorrhage (APH), oligohydramnios, and period of termination of pregnancy. 2. Delivery-related complications - mode of delivery, fetal distress, birth weight. 3. Neonatal Complications- Birth asphyxia, Neonatal Intensive Care Unit (NICU) admission, neonatal jaundice (hyperbillirubinaemia), Respiratory distress syndrome, Preterm birth, low birth weight (LBW), appearance, pulse, grimace, activity, and respiration score in 1 min and 5 mins, stillbirths (if any).</p><p><strong>Results: </strong>Group A-period of gestation (POG) at termination (36.99+/-2.70), more mean birth weight (2.8+/-0.424) <i>P</i> = 0.04, less NICU admission (<i>P</i> = 0.03). IUGR was less (<i>P</i> = 0.005). Hyperbilirubinemia was more common among group B (0.017), and term birth was more common in group A (0.046). LBW was higher among Group B (0.007).</p><p><strong>Conclusion: </strong>With thyroxine supplementation POG at termination, this study shows that mean birth weight was higher, NICU admissions were lower, and IUGR was lower. There was no discernible variation in other outcomes. Because this was a pilot study, the sample size was modest. Larg
背景:在促甲状腺激素升高的情况下,正常游离甲状腺素水平构成亚临床甲状腺功能减退症(TSH)。妊娠期间甲状腺生理变化导致正常TSH范围低于非妊娠期。妊娠期亚临床甲状腺疾病与不良结局相关,包括不良妊娠风险和新生儿结局。印度的患病率为6-8%。抗体的流行率因种族而异。妊娠TSH浓度>2.5 mIU/L需要评估甲状腺过氧化物酶抗体(TPO)抗体状态。文献和指南支持在TPO抗体阳性和TPO阴性且TSH bb0 10 mIU/L的患者中补充甲状腺素。然而,关于TPO抗体阴性的孕妇和TSH存在许多争论目的:确定补充甲状腺素对TPO抗体阴性的亚临床甲状腺功能减退孕妇的影响。这是一项前瞻性随机对照研究,在印度东部三级保健研究所进行。在这项试验中,对所有前往三级保健机构门诊的孕妇进行了TSH估计。TSH值>2.5受TPO抗体估计。纳入TSH值2.5 ~ 5.0 mIU/L、TPO抗体阴性的患者。共纳入60例,随机分为两组(A组和B组)。a组补充甲状腺素,b组安慰剂(叶酸)。甲状腺水平每隔一段时间测量一次。随访妊娠、分娩和新生儿并发症。我们研究了以下结果:1。妊娠相关并发症:妊娠期高血压、妊娠期糖尿病、妊娠期肝内胆汁淤积(IHCP)、子宫内生长迟缓(IUGR)、产前出血(APH)、羊水过少、终止妊娠期。2. 分娩相关并发症-分娩方式,胎儿窘迫,出生体重。3. 新生儿并发症-出生窒息,新生儿重症监护病房(NICU)入院,新生儿黄疸(高胆红素血症),呼吸窘迫综合征,早产,低出生体重(LBW),外观,脉搏,鬼脸,活动,1分钟和5分钟呼吸评分,死胎(如果有)。结果:a组妊娠期(POG)终止(36.99+/-2.70),平均出生体重(2.8+/-0.424)P = 0.04,新生儿重症监护病房入院(P = 0.03)较少。IUGR较低(P = 0.005)。B组高胆红素血症发生率较高(0.017),A组足月发生率较高(0.046)。B组LBW较高(0.007)。结论:在妊娠终止时补充甲状腺素,本研究显示平均出生体重较高,新生儿重症监护病房入院率较低,IUGR较低。其他结果没有明显的变化。因为这是一项初步研究,所以样本量不大。在未来的研究中可能会使用更大的样本。
{"title":"A randomized control trial comparing the clinical outcome of thyroxine supplementation in thyroid peroxide antibody- negative cases in patients with subclinical hypothyroidism in pregnancy.","authors":"Mukta Agarwal, Shivangni Sinha, Divenndu Bhushan, Ishita Roy, Simran Simran","doi":"10.4103/jfmpc.jfmpc_1874_24","DOIUrl":"https://doi.org/10.4103/jfmpc.jfmpc_1874_24","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;A normal free thyroxine level in the presence of an increased thyroid-stimulating hormone is what constitutes subclinical hypothyroidism (TSH). Changes in thyroid physiology during pregnancy result in the normal TSH range being lower than non-pregnant. Subclinical thyroid disease during pregnancy is associated with adverse outcomes, including, risk of adverse pregnancy and neonatal outcomes. Prevalence in India is 6-8%. The prevalence of antibodies varies with ethnicity. Pregnancy with TSH concentrations &gt;2.5 mIU/L needs evaluation for thyroid peroxidase antibody (TPO) antibody status. Literature and guidelines support Thyroxine supplementation in TPO antibody-positive patients and TPO-negative with TSH &gt;10 mIU/L. However, there are numerous debates around pregnant individuals with TPO antibody negative and TSH &lt;10 mIU/L.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To determine the effect of thyroxine supplementation in pregnant women with TPO antibody-negative subclinical hypothyroidism. It is a prospective randomized control study conducted in the tertiary care institute of eastern India. In this trial, a TSH estimation of all pregnant women visiting the OPD of a tertiary care institute was performed. TSH values &gt;2.5 are subjected to TPO antibody estimation. Patients with TSH value 2.5-5.0 mIU/L and TPO antibody negative were included. A total of 60 cases were included, randomized into two groups (Group A and B). Group A-thyroxine supplemented, Group B-placebo (folic acid). Thyroid levels are measured at intervals. Followed up for pregnancy, delivery, and neonatal complications. We studied the following outcomes: 1. Pregnancy-related complications - Gestational hypertension, gestational diabetes mellitus, and intrahepatic cholestasis of pregnancy (IHCP), intra-uterine growth retardation (IUGR), Antepartum hemorrhage (APH), oligohydramnios, and period of termination of pregnancy. 2. Delivery-related complications - mode of delivery, fetal distress, birth weight. 3. Neonatal Complications- Birth asphyxia, Neonatal Intensive Care Unit (NICU) admission, neonatal jaundice (hyperbillirubinaemia), Respiratory distress syndrome, Preterm birth, low birth weight (LBW), appearance, pulse, grimace, activity, and respiration score in 1 min and 5 mins, stillbirths (if any).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Group A-period of gestation (POG) at termination (36.99+/-2.70), more mean birth weight (2.8+/-0.424) &lt;i&gt;P&lt;/i&gt; = 0.04, less NICU admission (&lt;i&gt;P&lt;/i&gt; = 0.03). IUGR was less (&lt;i&gt;P&lt;/i&gt; = 0.005). Hyperbilirubinemia was more common among group B (0.017), and term birth was more common in group A (0.046). LBW was higher among Group B (0.007).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;With thyroxine supplementation POG at termination, this study shows that mean birth weight was higher, NICU admissions were lower, and IUGR was lower. There was no discernible variation in other outcomes. Because this was a pilot study, the sample size was modest. Larg","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 1","pages":"75-81"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12975049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of immunization status on nutrition among 12-23-month-old children in Telangana-A cross-sectional study. 泰伦加纳邦12-23月龄儿童免疫状况对营养影响的横断面研究
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_69_25
Shadan Butool, G Kiranmayee, Sandeep K Dharnamoni, Syed A Mohiuddin

Purpose/background: Malnutrition and incomplete immunization remain major public health challenges in India. This study has been conducted to determine whether a child's immunization status has an influence on their nutritional status.

Aims: (1) To assess the nutritional status and primary immunization coverage in children aged 12-23 months. (2) To determine the association between sociodemographic factors, nutritional status, and immunization status.

Methods: A comparative community-based cross-sectional study was conducted over four months (from March to June 2023) involving children aged 12-23 months in both urban and rural practice areas associated with the Osmania Medical College. The study included a sample of 400 children, 200 from urban settings and 200 from rural locations, selected using a multistage sampling approach. Chi-square test and binary logistic regression were used for statistical analysis.

Results: The coverage of full immunization, partial immunization, and nonimmunization in urban area is 65%, 34%, and 1%, while in rural area is 48.5%, 49%, and 2.5%, respectively. Underweight, stunted, wasted, and severe acute malnutrition (SAM) children in the urban area are 26%, 23.5%, 11%, and 3.5%, while in rural area, underweight, stunted, wasted, and SAM children are 26%, 32%, 16%, and 5.5%. Statistical analysis shows significant associations between malnutrition and immunization status and various types of malnutrition and independent variables, factors like immunization status, residence, family type, socioeconomic status, and mother's age showed a significant association.

Conclusions: Though progress has been made, achieving universal coverage for nutrition and immunization requires collaboration, planning and monitoring, and systemic changes across all levels of healthcare.

目的/背景:营养不良和免疫不完全仍然是印度面临的主要公共卫生挑战。这项研究是为了确定儿童的免疫状况是否会影响他们的营养状况。目的:(1)评估12-23月龄儿童营养状况和初级免疫覆盖率。(2)确定社会人口因素、营养状况和免疫状况之间的关系。方法:在为期4个月(2023年3月至6月)的比较社区横断面研究中,涉及与Osmania医学院相关的城市和农村实践区12-23个月的儿童。该研究包括400名儿童的样本,其中200名来自城市,200名来自农村,采用多阶段抽样方法选择。采用卡方检验和二元logistic回归进行统计分析。结果:城市地区全面免疫、部分免疫和不免疫覆盖率分别为65%、34%和1%,农村地区为48.5%、49%和2.5%。城市地区体重不足、发育不良、消瘦和严重急性营养不良(SAM)儿童比例分别为26%、23.5%、11%和3.5%,农村地区体重不足、发育不良、消瘦和严重急性营养不良儿童比例分别为26%、32%、16%和5.5%。统计分析显示,营养不良与免疫状况、各种类型营养不良之间存在显著相关性,免疫状况、居住地、家庭类型、社会经济地位、母亲年龄等自变量与营养不良之间存在显著相关性。结论:尽管取得了进展,但要实现营养和免疫的普遍覆盖,需要各级卫生保健机构之间的协作、规划和监测以及系统性变革。
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引用次数: 0
Prevalence, perceptions, and mental health impacts of e-cigarette use in adults in outpatient settings. 门诊成人电子烟使用的流行、认知和心理健康影响
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_1175_25
Ebtisam M F Alhawsawi, Sulhi A Alfakeh, Atheer M Almalki, Roaa K Abdulkareem, Maya S Khider, Zubaida H Khan, Maha A Alzahrani, Reem A Alghamdi, Seba S Algarni, Roaa A Alghamdi, Weaam W Murad, Rafah B Hariri

Introduction: As e-cigarettes become more popular, especially among young adults, worries about their effects on physical and mental health are increasing. This study examines the prevalence, social influences, and health perceptions related to e-cigarette use in Jeddah.

Methods: We surveyed 402 adults attending outpatient clinics at King Abdulaziz University Hospital in Jeddah. Participants provided insights on their smoking habits, beliefs about e-cigarettes, and mental health status through validated questionnaires.

Results: Among participants, 7.7% were e-cigarette users, with 56.2%. Social influence is identified as a main reason for usage. Despite the appeal, a large majority (74.4%) recognized the harmful effects of e-cigarettes, associating them with respiratory, cardiac, and cancer risks. Interestingly, while no direct link was found between e-cigarette use and specific health issues, a potential connection to heightened anxiety was observed. The influence of peers played a major role in initiating use.

Conclusion: E-cigarette use is on the rise, driven largely by social factors, with many users acknowledging the health risks. This study highlights the necessity for focused public health campaigns to raise awareness, particularly among young adults. Further research is essential to fully understand the mental health implications of e-cigarette use and its long-term effects on well-being.

引言:随着电子烟越来越受欢迎,尤其是在年轻人中,人们越来越担心电子烟对身心健康的影响。本研究调查了吉达与电子烟使用有关的流行程度、社会影响和健康观念。方法:我们调查了在吉达阿卜杜勒阿齐兹国王大学医院门诊就诊的402名成年人。参与者通过有效的问卷提供了他们的吸烟习惯、对电子烟的看法和心理健康状况的见解。结果:在参与者中,7.7%是电子烟使用者,占56.2%。社会影响被认为是使用的主要原因。尽管有吸引力,但大多数人(74.4%)认识到电子烟的有害影响,将其与呼吸、心脏和癌症风险联系起来。有趣的是,虽然没有发现使用电子烟与特定健康问题之间的直接联系,但观察到电子烟与焦虑加剧的潜在联系。同伴的影响在开始使用中起着重要作用。结论:电子烟的使用量正在上升,主要是受社会因素的推动,许多用户承认其健康风险。这项研究强调有必要开展重点突出的公共卫生运动,以提高认识,特别是在年轻人中间。为了充分了解电子烟使用对心理健康的影响及其对健康的长期影响,进一步的研究是必不可少的。
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引用次数: 0
Interpretable XGBoost-SHAP model predicts short-term recurrence after first-episode acute pancreatitis. 可解释的XGBoost-SHAP模型预测首发急性胰腺炎后短期复发。
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_564_25
Xiao Mei Yang, Shun Yi Feng

Objective: To construct an eXtreme Gradient Boosting (XGBoost) model for predicting short-term recurrence after first-episode acute pancreatitis (AP) and employ SHapley Additive exPlanations (SHAP) analysis for feature interpretation.

Methods: A total of 442 patients with first-episode AP admitted to Cangzhou Central Hospital from October 2018 to June 2023 were retrospectively analyzed. The short-term recurrence was defined as a second attack after first-episode AP within 1 year. The cohort was split randomly, with 70% of the patients (n = 321) used for model training and 30% (n = 121) reserved for validation. Cox regression analysis was employed to identify independent predictors affecting recurrence, and an XGBoost model was constructed based on predictors. The XGBoost model was assessed by using area under the curve (AUC), calibration curve, decision curve analysis (DCA), and SHAP analysis.

Results: Three features were determined as predictors of recurrence. They included elevated triglycerides, alcohol drinking, and pancreatic necrosis. The XGBoost model demonstrated favorable performance, achieving an AUC of 0.933 (95% CI: 0.895-0.970) in the training cohort and of 0.874 (95% CI: 0.777-0.970) in the validation cohort. The calibration curve exhibited strong consistency between the anticipated and observed values, and DCA confirmed that the XGBoost model provided great clinical benefit. SHAP analysis also proved that elevated triglycerides, alcohol drinking, and pancreatic necrosis were decisive for the effect of the XGBoost model.

Conclusion: The XGBoost model can accurately predict short-term recurrence. The SHAP approach can enhance the interpretability of the machine-learning model and support clinical decision-making.

目的:构建预测首发急性胰腺炎(AP)短期复发的极限梯度增强(XGBoost)模型,并采用SHapley加性解释(SHAP)分析进行特征解释。方法:回顾性分析2018年10月至2023年6月沧州市中心医院收治的442例首发AP患者。短期复发定义为首次发作AP后1年内再次发作。随机分组,其中70%的患者(n = 321)用于模型训练,30% (n = 121)用于验证。采用Cox回归分析确定影响复发的独立预测因子,并基于预测因子构建XGBoost模型。采用曲线下面积(AUC)、校准曲线、决策曲线分析(DCA)和SHAP分析对XGBoost模型进行评价。结果:确定了三个特征作为复发的预测因素。它们包括甘油三酯升高、饮酒和胰腺坏死。XGBoost模型表现出良好的性能,在训练队列中AUC为0.933 (95% CI: 0.895-0.970),在验证队列中AUC为0.874 (95% CI: 0.777-0.970)。校准曲线在预测值和实测值之间表现出很强的一致性,DCA证实XGBoost模型具有很大的临床效益。SHAP分析还证明,甘油三酯升高、饮酒和胰腺坏死是XGBoost模型效果的决定性因素。结论:XGBoost模型能准确预测短期复发。SHAP方法可以增强机器学习模型的可解释性,并支持临床决策。
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引用次数: 0
Safety and effectiveness of topical dapsone in acne treatment: A review. 外用氨苯砜治疗痤疮的安全性和有效性综述。
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_256_25
Sami N Alsuwaidan, Tala A Qadoumi

Oral dapsone is effective in treating several dermatologic conditions, including acne vulgaris. However, the rate of adverse effects of oral dapsone is a concern when prescribing it. Topical dapsone may mitigate these adverse effects and enhance the safety and tolerability of dapsone. Here, we review the published reports and studies to examine the efficacy and safety of topical dapsone in treating acne. A literature review was conducted using the PubMed database. The review considered patient and disease factors, such as the type of acne, acne location, patient gender, age, skin type, and race. Other factors, such as the duration and dosage of treatment, monotherapy versus combination therapy, adverse events, and safety profiles, were also compared. Topical dapsone was well tolerated and effective across a variety of acne presentations and patient subgroups. It showed a favorable safety profile, even in patients with comorbidities, such as G6PD deficiency. We conclude that topical dapsone is safe, effective, and well tolerated in the treatment of acne, contrary to its oral form.

口服氨苯砜是有效的治疗几种皮肤病,包括寻常痤疮。然而,口服氨苯砜的不良反应率在开处方时是一个值得关注的问题。局部应用氨苯砜可减轻这些不良反应,提高氨苯砜的安全性和耐受性。在这里,我们回顾了已发表的报告和研究,以检查外用氨苯砜治疗痤疮的有效性和安全性。使用PubMed数据库进行文献综述。该综述考虑了患者和疾病因素,如痤疮类型、痤疮位置、患者性别、年龄、皮肤类型和种族。其他因素,如治疗的持续时间和剂量,单药与联合治疗,不良事件和安全性,也进行了比较。局部氨苯砜在各种痤疮表现和患者亚组中具有良好的耐受性和有效性。它显示出良好的安全性,即使是有合并症的患者,如G6PD缺乏症。我们的结论是,与口服形式相反,局部应用氨苯砜治疗痤疮是安全、有效和耐受性良好的。
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引用次数: 0
Demographic and conceptual disparities in systemic lupus erythematosus: A comparative analysis from Riyadh, Saudi Arabia. 系统性红斑狼疮的人口统计学和概念差异:来自沙特阿拉伯利雅得的比较分析。
IF 1 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2026-02-07 DOI: 10.4103/jfmpc.jfmpc_1812_25
Abdulelah F Alshehri, Meshal Alzakari, Abdulmohsen S Alanazi, Osama Thamer Al-Ahmari, Mohammed S Alsaadan, Rayan Saleh Alzahrani, Khalid Alshammari, Faisal M Almutairi, Mohammed S Alshihri, Nawaf F Alhagbani, Musab Alsulami, Abdullatif Essa Aldhafyan, Ibrahim A Alamer, Salem Alhumaid, Mohammed Almashali

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs and may lead to serious complications if not detected and treated early. Raising public awareness about SLE is crucial for early diagnosis and management. This study aimed to assess the level of knowledge, awareness, and attitudes regarding SLE among the general population in the Riyadh region of Saudi Arabia.

Methods: A descriptive, cross-sectional study was conducted among residents of the Riyadh region aged 18 years and older. Data were collected using an online validated questionnaire distributed via social media platforms. The questionnaire measured sociodemographic data, general knowledge about SLE, understanding of its causes, symptoms, complications, and treatment, as well as public attitudes. Descriptive analysis and Chi-square tests were used to determine associations between demographic variables and knowledge levels, using SPSS version 25.

Results: A total of 646 participants completed the survey. Only 14.8% of respondents knew that SLE is an autoimmune disease, and 38.7% recognized that it can affect multiple organs. Furthermore, only 33.9% were aware of its potentially life-threatening complications. Significant associations were found between awareness levels and age group (P = 0.000), gender (P = 0.002), and educational level (P = 0.000). The majority (71.3%) expressed a desire to learn more about SLE, and 77.2% agreed that public health campaigns are needed to improve awareness.

Conclusions: This study revealed a significant lack of knowledge and awareness of SLE in the Riyadh region. The findings emphasize the need for targeted educational campaigns and public health efforts to improve early recognition and management of SLE, thereby reducing disease-related complications.

背景:系统性红斑狼疮(SLE)是一种影响多器官的慢性自身免疫性疾病,如果不及早发现和治疗,可能导致严重的并发症。提高公众对SLE的认识对于早期诊断和管理至关重要。本研究旨在评估沙特阿拉伯利雅得地区普通人群对SLE的知识、意识和态度水平。方法:在利雅得地区18岁及以上的居民中进行了一项描述性横断面研究。通过社交媒体平台分发的在线有效问卷收集数据。问卷测量了社会人口学数据、SLE的一般知识、对其病因、症状、并发症和治疗的了解,以及公众的态度。采用描述性分析和卡方检验来确定人口统计变量与知识水平之间的关联,使用SPSS版本25。结果:共有646名参与者完成了调查。只有14.8%的受访者知道SLE是一种自身免疫性疾病,38.7%的受访者知道SLE可累及多器官。此外,只有33.9%的人知道其可能危及生命的并发症。认知水平与年龄组(P = 0.000)、性别(P = 0.002)和教育水平(P = 0.000)之间存在显著关联。大多数人(71.3%)表示希望更多地了解SLE, 77.2%的人同意需要开展公共卫生运动来提高认识。结论:这项研究揭示了利雅得地区严重缺乏对SLE的认识和认识。研究结果强调了有针对性的教育活动和公共卫生努力的必要性,以提高SLE的早期识别和管理,从而减少疾病相关并发症。
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引用次数: 0
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Journal of Family Medicine and Primary Care
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