Received: August, 10, 2020 Revised: September, 7, 2020 Available online: February, 2021 Diabetes mellitus type 2 is a metabolic disorder, namely a decrease in peripheral tissues' response to insulin. Free radicals increase, which results in the forming of Malondialdehyde (MDA). Roselle flower petals is an antioxidant to reduce free radical damage. This study aims to analyze the effect of roselle petal extract on decreased MDA levels in mice induced by diabetes. The rats were divided into four treatments group as follow: 1) control negative, 2) control positive, 3) treatment dose I (administering roselle petal extract 195 mg/200 gram body weight), 4) treatment dose II (giving roselle petal extract 260mg/ 200 gram body weight). MDA levels were measured using Thiobarbituric acid (TBA) assay. There was an effect of rosella petal extract in the group with 260 mg/200 of rosella petal extract (p=0.005) and 195 mg/200 of rosella petal extract (p=0.041) compared with the positive control group. Rosella petal extract significantly reduces MDA levels in rats induced by type 2 diabetes.
{"title":"Effect Of Roselle Petal Extract On Decreased Levels Of Mda In Rats With Type 2 Diabetes","authors":"Novera Herdiani, E. Wikurendra","doi":"10.33086/JHS.V14I1.1688","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1688","url":null,"abstract":"Received: August, 10, 2020 Revised: September, 7, 2020 Available online: February, 2021 Diabetes mellitus type 2 is a metabolic disorder, namely a decrease in peripheral tissues' response to insulin. Free radicals increase, which results in the forming of Malondialdehyde (MDA). Roselle flower petals is an antioxidant to reduce free radical damage. This study aims to analyze the effect of roselle petal extract on decreased MDA levels in mice induced by diabetes. The rats were divided into four treatments group as follow: 1) control negative, 2) control positive, 3) treatment dose I (administering roselle petal extract 195 mg/200 gram body weight), 4) treatment dose II (giving roselle petal extract 260mg/ 200 gram body weight). MDA levels were measured using Thiobarbituric acid (TBA) assay. There was an effect of rosella petal extract in the group with 260 mg/200 of rosella petal extract (p=0.005) and 195 mg/200 of rosella petal extract (p=0.041) compared with the positive control group. Rosella petal extract significantly reduces MDA levels in rats induced by type 2 diabetes.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"40 1","pages":"48-52"},"PeriodicalIF":0.0,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86494539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Received: September, 1, 2020 Revised: November, 7, 2020 Available online: February, 2021 Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) in Indonesia are deadly infectious diseases. This disease will always be a problem at the national and global levels. The impact that often occurs, especially in children with HIV/AIDS, is psychological changes, namely stress. Efforts to overcome its disturbance are storytelling and music therapy. This research aims to apply storytelling and music therapy to reduce stress in children with HIV/AIDS. This research method was a quasi-experiment with a research design involving 1 group (one group pre-posttest), containing 30 respondents aged 6-10 years with HIV/AIDS by purposive sampling. The independent variable was storytelling and music therapy, while the dependent variable was stress levels. The instrument used Hamilton Anxiety Questionaire (HAM-A). The results of the study showed that 26 samples (86.7%) experienced decreased stress levels. Analysis of Wilcoxon sign rank test obtained α=0.009, which means there was a difference before and after therapy. The combination of music therapy and storytelling can be a better alternative in reducing stress in children – by considering age, environment, and children's emotions to have an optimal effect).
{"title":"Combination of Storytelling and Music Therapy to Reduce Stress in Children with HIV/AIDS and Discrimination in Surabaya","authors":"Taufan Citra Darmawan","doi":"10.33086/JHS.V14I1.1749","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1749","url":null,"abstract":"Received: September, 1, 2020 Revised: November, 7, 2020 Available online: February, 2021 Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) in Indonesia are deadly infectious diseases. This disease will always be a problem at the national and global levels. The impact that often occurs, especially in children with HIV/AIDS, is psychological changes, namely stress. Efforts to overcome its disturbance are storytelling and music therapy. This research aims to apply storytelling and music therapy to reduce stress in children with HIV/AIDS. This research method was a quasi-experiment with a research design involving 1 group (one group pre-posttest), containing 30 respondents aged 6-10 years with HIV/AIDS by purposive sampling. The independent variable was storytelling and music therapy, while the dependent variable was stress levels. The instrument used Hamilton Anxiety Questionaire (HAM-A). The results of the study showed that 26 samples (86.7%) experienced decreased stress levels. Analysis of Wilcoxon sign rank test obtained α=0.009, which means there was a difference before and after therapy. The combination of music therapy and storytelling can be a better alternative in reducing stress in children – by considering age, environment, and children's emotions to have an optimal effect).","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"99 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89920451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Lestari, Niken Grah Prihartanti, Mamik Ratnawati
Received: September, 5, 2020 Revised: December, 2, 2020 Available online: February, 2021 The causes of death for newborns 0-6 days in Indonesia are 36.9% respiratory disorders, 32.4% premature birth, 12% sepsis, 6.8% hypothermia, and 6.6% neonatal jaundice. A preliminary study in Comprehensive Emergency Services Neonatal Obstetric (PONEK) of Jombang Regional Public Hospital (RSUD Jombang) reported that the incidence of asphyxia neonatorum was 295 cases in 2016 and 341 cases in 2015. There were 98 cases of preterm delivery in 2016. This study aims to prove the effect of corticosteroid administration on neonatal asphyxia in mothers with preterm delivery. This study was an analytical study using a one-group after only design. The population was all women giving birth at RSUD Jombang with preterm labor diagnosis in January-May 2017, while the sample was 82. The instruments utilized questionnaires and checklists. The bivariate analysis applied the chi-square association test. Based on the results of the chisquare test χ2= 4.622> χ2 table; p = 0.009 <α (0.05). There was a correlation between corticosteroid administration and the incidence of asphyxia neonatorum in women with preterm delivery. This study's results could be an input for primary health care facilities to prevent neonatal asphyxia. Further research should develop other similar variables and increase the number of respondents.
{"title":"The Role Of Corticosteroid Administration On The Incidents Of Asphyxia Neonatorum Among Mothers With Preterm Delivery In Ponek Rsud Jombang","authors":"R. Lestari, Niken Grah Prihartanti, Mamik Ratnawati","doi":"10.33086/JHS.V14I1.1297","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1297","url":null,"abstract":"Received: September, 5, 2020 Revised: December, 2, 2020 Available online: February, 2021 The causes of death for newborns 0-6 days in Indonesia are 36.9% respiratory disorders, 32.4% premature birth, 12% sepsis, 6.8% hypothermia, and 6.6% neonatal jaundice. A preliminary study in Comprehensive Emergency Services Neonatal Obstetric (PONEK) of Jombang Regional Public Hospital (RSUD Jombang) reported that the incidence of asphyxia neonatorum was 295 cases in 2016 and 341 cases in 2015. There were 98 cases of preterm delivery in 2016. This study aims to prove the effect of corticosteroid administration on neonatal asphyxia in mothers with preterm delivery. This study was an analytical study using a one-group after only design. The population was all women giving birth at RSUD Jombang with preterm labor diagnosis in January-May 2017, while the sample was 82. The instruments utilized questionnaires and checklists. The bivariate analysis applied the chi-square association test. Based on the results of the chisquare test χ2= 4.622> χ2 table; p = 0.009 <α (0.05). There was a correlation between corticosteroid administration and the incidence of asphyxia neonatorum in women with preterm delivery. This study's results could be an input for primary health care facilities to prevent neonatal asphyxia. Further research should develop other similar variables and increase the number of respondents.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"14 1","pages":"77-81"},"PeriodicalIF":0.0,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81699161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Received: January, 24, 2020 Revised: April, 17, 2020 Available online: February, 2021 Stunting is a chronic malnutrition problem that resulted from an insufficient nutritional intake for a long time. This problem can develop during pregnancy, infancy, childhood, and throughout the life cycle due to feeding that does not accommodate the nutritional needs. Stunting correlates with disorders of fine motor, gross motor, language, and personal social skills. This study aims to perceive an overview of stunted toddlers aged 24-59 months using the Prescreening Developmental Questionnaire (PDQ). The authors carried out this research in Air Dingin public health center, Padang, from April to September 2019. This research was descriptive that included 40 toddlers aged 24-59 months diagnosed with stunting. The data presentation was a frequency distribution table and percentage. This study obtained that 22 toddlers (55.0%) were girls, seven toddlers (17.5%) experienced a developmental deviation, and 26 toddlers (65%) had suspected developmental deviation. In short, there were several cases of stunted toddlers who underwent a developmental deviation.
{"title":"Development Of Stunted Toddlers Aged 24-59 Months Using Prescreening Developmental Questionnaire (Pdq) In Air Dingin Public Health Center, Padang 2019: An Overview","authors":"D. Hasni, Febianne Eldrian, Anjas Adisena","doi":"10.33086/JHS.V14I1.1447","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1447","url":null,"abstract":"Received: January, 24, 2020 Revised: April, 17, 2020 Available online: February, 2021 Stunting is a chronic malnutrition problem that resulted from an insufficient nutritional intake for a long time. This problem can develop during pregnancy, infancy, childhood, and throughout the life cycle due to feeding that does not accommodate the nutritional needs. Stunting correlates with disorders of fine motor, gross motor, language, and personal social skills. This study aims to perceive an overview of stunted toddlers aged 24-59 months using the Prescreening Developmental Questionnaire (PDQ). The authors carried out this research in Air Dingin public health center, Padang, from April to September 2019. This research was descriptive that included 40 toddlers aged 24-59 months diagnosed with stunting. The data presentation was a frequency distribution table and percentage. This study obtained that 22 toddlers (55.0%) were girls, seven toddlers (17.5%) experienced a developmental deviation, and 26 toddlers (65%) had suspected developmental deviation. In short, there were several cases of stunted toddlers who underwent a developmental deviation.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"1 1","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87558762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irma Prasetyowati, A. E. Noveyani, Ni'mal Baroya, Wahyu Martina Sari, Heni Nuraini, Abdulfeta Ali, Ana Masfurotin Ni’mah, Dena Anggraeni Harjanto
Received: July, 9, 2020 Revised: November, 12, 2020 Available online: February, 2021 The number of people living with HIV/AIDS in Indonesia is increasing every year. HIV/AIDS surveillance is the most effective way to control the spreading of HIV/AIDS cases. This study aims to describe the implementation of HIV/AIDS surveillance in Jember. This paper was a descriptive study that included all public health centers (PHCs) conducting HIV/AIDS surveillance. The sample was the Jember District Departement of Health Office and four PHCs using purposive sampling. Variables in this study were input, process, and output. The data was obtained from an interview using a questionnaire. The results indicated that the four PHCs did not have an epidemiologist. Data collection mostly derived from Voluntary Counseling and Testing (VCT) and mobile VCT. Processing HIV/AIDS surveillance data utilized the HIV/AIDS and STDs Information System (SIHA) application and validated by the District Department of Health Office once a month. However, only two PHCs conducted analysis and data interpretation. Dissemination was only done by the District Departement of Health Office and 2 out of 4 PHCs. Hence, the components and process of surveillance needed to be optimized.
{"title":"Surveillance Implementation Of Hiv/Aids In Jember Regency","authors":"Irma Prasetyowati, A. E. Noveyani, Ni'mal Baroya, Wahyu Martina Sari, Heni Nuraini, Abdulfeta Ali, Ana Masfurotin Ni’mah, Dena Anggraeni Harjanto","doi":"10.33086/JHS.V14I1.1646","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1646","url":null,"abstract":"Received: July, 9, 2020 Revised: November, 12, 2020 Available online: February, 2021 The number of people living with HIV/AIDS in Indonesia is increasing every year. HIV/AIDS surveillance is the most effective way to control the spreading of HIV/AIDS cases. This study aims to describe the implementation of HIV/AIDS surveillance in Jember. This paper was a descriptive study that included all public health centers (PHCs) conducting HIV/AIDS surveillance. The sample was the Jember District Departement of Health Office and four PHCs using purposive sampling. Variables in this study were input, process, and output. The data was obtained from an interview using a questionnaire. The results indicated that the four PHCs did not have an epidemiologist. Data collection mostly derived from Voluntary Counseling and Testing (VCT) and mobile VCT. Processing HIV/AIDS surveillance data utilized the HIV/AIDS and STDs Information System (SIHA) application and validated by the District Department of Health Office once a month. However, only two PHCs conducted analysis and data interpretation. Dissemination was only done by the District Departement of Health Office and 2 out of 4 PHCs. Hence, the components and process of surveillance needed to be optimized.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"22 1","pages":"53-62"},"PeriodicalIF":0.0,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82081502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Received: September, 14, 2020 Revised: November 4, 2020 Available online: February 2021 Advances in technology and high activities at work cause a person to prefer fast food, increasing the risks of high cholesterol levels. Meanwhile, the healing of hypercholesterolemia requires a long treatment time. One of them is nonpharmacological treatment using Vernonia amygdalina (African bitter leaf) tea. This study analyzes V.amygdalina (African bitter leaf) effectiveness for reducing the cholesterol levels in individuals with hypercholesterolemia. The design of this study was a quasi-experimental design, with a non-equivalent control group design. The population involved individuals with hypercholesterolemia in the village of Kedensari RW 05 Tanggulangin, Sidoarjo. There were 40 respondents in this study using the purposive sampling technique – 20 respondents in the experimental group and 20 respondents in the control group. The independent variable was V.amygdalina tea, whereas the dependent variable was cholesterol levels. The data were analyzed using the Wilcoxon and Mann-Whitney tests. The p-value of the Wilcoxon test and MannWhitney signed-ranks test was (0.000)<α(0.005), which illustrated that V.amygdalina (African bitter leaf) tea was useful for the treatment of hypercholesterolemia.
{"title":"The Effectiveness Of Vernonia Amygdalina (African Bitter Leaf) Tea For Reducing Cholesterol Levels In Individuals With Hypercholesterolemia","authors":"Nunik Purwanti, R. Aditya","doi":"10.33086/JHS.V14I1.1759","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1759","url":null,"abstract":"Received: September, 14, 2020 Revised: November 4, 2020 Available online: February 2021 Advances in technology and high activities at work cause a person to prefer fast food, increasing the risks of high cholesterol levels. Meanwhile, the healing of hypercholesterolemia requires a long treatment time. One of them is nonpharmacological treatment using Vernonia amygdalina (African bitter leaf) tea. This study analyzes V.amygdalina (African bitter leaf) effectiveness for reducing the cholesterol levels in individuals with hypercholesterolemia. The design of this study was a quasi-experimental design, with a non-equivalent control group design. The population involved individuals with hypercholesterolemia in the village of Kedensari RW 05 Tanggulangin, Sidoarjo. There were 40 respondents in this study using the purposive sampling technique – 20 respondents in the experimental group and 20 respondents in the control group. The independent variable was V.amygdalina tea, whereas the dependent variable was cholesterol levels. The data were analyzed using the Wilcoxon and Mann-Whitney tests. The p-value of the Wilcoxon test and MannWhitney signed-ranks test was (0.000)<α(0.005), which illustrated that V.amygdalina (African bitter leaf) tea was useful for the treatment of hypercholesterolemia.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"85 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90723316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Received: April, 19, 2020 Revised: September, 30, 2020 Available online: February, 2021 Children will grow faster when their mother stimulate their development. But in fact, parents' awareness is still low due to parents' reluctance. They believe that stimulation is for children with developmental delay. This research aims to describe the mothers' motivation in the developmental stimulation of children aged 1-3 years old in Sambungrejo Village District Sidoarjo. This study used a descriptive design. The population was mothers with children age 1–3 years in Sambungrejo Village Sukodono Sidoarjo. There were 50 respondents with simple random sampling. The research variable was mothers' motivation in the developmental stimulation of children aged 1-3 years. The instrument utilized a questionnaire. The data analysis was frequency distribution. The results showed that 62,5% of respondents had low motivation, while 37,5% of respondents had a high motive to perform stimulation in developing children aged 1–3. The study concludes that most mothers have low motivation in developmental stimulation. Health workers should give health education about the developmental stimulation of children to mothers.
{"title":"Description Of Mothers' Motivation In Developmental Stimulation Of Children Aged 1 - 3 Years Old In Sambungrejo Village, Sidoarjo","authors":"R. Anggraini, Wahyu Anjas Sari","doi":"10.33086/JHS.V14I1.1943","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1943","url":null,"abstract":"Received: April, 19, 2020 Revised: September, 30, 2020 Available online: February, 2021 Children will grow faster when their mother stimulate their development. But in fact, parents' awareness is still low due to parents' reluctance. They believe that stimulation is for children with developmental delay. This research aims to describe the mothers' motivation in the developmental stimulation of children aged 1-3 years old in Sambungrejo Village District Sidoarjo. This study used a descriptive design. The population was mothers with children age 1–3 years in Sambungrejo Village Sukodono Sidoarjo. There were 50 respondents with simple random sampling. The research variable was mothers' motivation in the developmental stimulation of children aged 1-3 years. The instrument utilized a questionnaire. The data analysis was frequency distribution. The results showed that 62,5% of respondents had low motivation, while 37,5% of respondents had a high motive to perform stimulation in developing children aged 1–3. The study concludes that most mothers have low motivation in developmental stimulation. Health workers should give health education about the developmental stimulation of children to mothers.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"70 1","pages":"43-47"},"PeriodicalIF":0.0,"publicationDate":"2021-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78093831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Affecting Toddlers' Development in Pamekasan Regency","authors":"Nur Jayanti, Rohemah Rohemah, Uliyatul Laili","doi":"10.33086/JHS.V14I1.1942","DOIUrl":"https://doi.org/10.33086/JHS.V14I1.1942","url":null,"abstract":"","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"40 1","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"2021-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87022167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-15DOI: 10.17532/JHSCI.2021.1110
D. Galic, A. Cenov, D. Lušić, M. Glad, Slaven Jozić, Bruno Cvetković, Daniel Maestro, N. Maestro, D. Mance, Darija Vukić Lušić
Introduction: The Republic of Croatia (HR) has significantly invested in monitoring the quality of inland bathing areas during the past 10 years. The aim of this paper was to analyze the results obtained during the 2014-2019 period and to compare them with the Region (non-European Union [EU] countries neighboring Croatia) and EU. Moreover, bathing water quality data at two bathing areas of Zagreb (lakes Jarun and Bundek) were processed in more detail.Methods: The quality of inland bathing areas in the HR is monitored in five rivers and five lakes in nine Croatian counties; 19 of the 35 monitored sites are located in Zagreb County. Escherichia coli (EC) was determined by EN ISO 9308-3: 1998, while intestinal enterococci (ENT) were defined by EN ISO 7899-2: 2000. Statistical processing of the results was performed using the Microsoft Excel Statistical Package (Redmond, USA) and Statistica 13.5. (Stat.Sof.Inc., Tulsa, USA); the significance level was set to p < 0.05.Results: During the study period, the worst Croatian inland water quality was recorded in 2019 (excellent quality for only 25.9% of the bathing areas), while the best quality was recorded in 2015 (excellent quality in 57.1%). On average (2014-2019), the share of bathing areas with excellent quality in Croatia was 46.3% (i.e., under the EU average of 85.3%); with no poor locations (EU average was nearly 2%). A significant positive correlation was found between fecal indicators (EC&ENT) and the amount of precipitation, while a negative correlation with water and air temperature in lakes.Conclusions: The quality of Croatian inland bathing areas is significantly lower than the European average, while EU water quality is improving. Regarding the countries bordering Croatia, Italy, Slovenia, and Hungary have achieved better results, while Montenegro, Serbia, and Bosnia and Herzegovina are still in the process of developing the monitoring of the bathing water quality.
导言:克罗地亚共和国(HR)在过去十年中为监测内陆浴场的质量投入了大量资金。本文的目的是分析2014-2019年期间获得的结果,并将其与该地区(克罗地亚邻国的非欧盟[EU]国家)和欧盟进行比较。此外,对萨格勒布两个洗浴区(Jarun湖和Bundek湖)的洗浴水质数据进行了更详细的处理。方法:对克罗地亚9个县的5条河流和5个湖泊进行内陆浴场水质监测;35个监测场址中有19个位于萨格勒布县。大肠杆菌(EC)测定方法采用EN ISO 9308- 3:20 98,肠球菌(ENT)测定方法采用EN ISO 7899- 2:20 00。使用Microsoft Excel Statistical Package (Redmond, USA)和Statistica 13.5对结果进行统计处理。(Stat.Sof.Inc。(塔尔萨,美国);显著性水平设为p < 0.05。结果:在研究期间,克罗地亚内陆水质最差的年份是2019年(只有25.9%的浴场水质优良),而最好的年份是2015年(57.1%的浴场水质优良)。平均而言(2014-2019年),克罗地亚优质浴场的比例为46.3%(即低于欧盟85.3%的平均水平);没有贫困地区(欧盟平均水平接近2%)。粪便指标(EC&ENT)与降水量呈显著正相关,与湖泊水温和气温呈显著负相关。结论:克罗地亚内陆浴场水质明显低于欧洲平均水平,而欧盟水质正在改善。在与克罗地亚接壤的国家中,意大利、斯洛文尼亚和匈牙利取得了较好的成果,而黑山、塞尔维亚和波斯尼亚和黑塞哥维那仍在开展洗浴水质监测工作。
{"title":"Quality of Croatian Inland Bathing Areas: Reference to The Region and EU","authors":"D. Galic, A. Cenov, D. Lušić, M. Glad, Slaven Jozić, Bruno Cvetković, Daniel Maestro, N. Maestro, D. Mance, Darija Vukić Lušić","doi":"10.17532/JHSCI.2021.1110","DOIUrl":"https://doi.org/10.17532/JHSCI.2021.1110","url":null,"abstract":"Introduction: The Republic of Croatia (HR) has significantly invested in monitoring the quality of inland bathing areas during the past 10 years. The aim of this paper was to analyze the results obtained during the 2014-2019 period and to compare them with the Region (non-European Union [EU] countries neighboring Croatia) and EU. Moreover, bathing water quality data at two bathing areas of Zagreb (lakes Jarun and Bundek) were processed in more detail.Methods: The quality of inland bathing areas in the HR is monitored in five rivers and five lakes in nine Croatian counties; 19 of the 35 monitored sites are located in Zagreb County. Escherichia coli (EC) was determined by EN ISO 9308-3: 1998, while intestinal enterococci (ENT) were defined by EN ISO 7899-2: 2000. Statistical processing of the results was performed using the Microsoft Excel Statistical Package (Redmond, USA) and Statistica 13.5. (Stat.Sof.Inc., Tulsa, USA); the significance level was set to p < 0.05.Results: During the study period, the worst Croatian inland water quality was recorded in 2019 (excellent quality for only 25.9% of the bathing areas), while the best quality was recorded in 2015 (excellent quality in 57.1%). On average (2014-2019), the share of bathing areas with excellent quality in Croatia was 46.3% (i.e., under the EU average of 85.3%); with no poor locations (EU average was nearly 2%). A significant positive correlation was found between fecal indicators (EC&ENT) and the amount of precipitation, while a negative correlation with water and air temperature in lakes.Conclusions: The quality of Croatian inland bathing areas is significantly lower than the European average, while EU water quality is improving. Regarding the countries bordering Croatia, Italy, Slovenia, and Hungary have achieved better results, while Montenegro, Serbia, and Bosnia and Herzegovina are still in the process of developing the monitoring of the bathing water quality.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82189278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-22DOI: 10.17532/JHSCI.2021.1121
Nina Čamdžić, Suada Kuskunović-Vlahovljak, S. Radović, Mirsad Dorić, M. Babić, Edina Lazović Salčin, A. Spahić
Introduction: Tumor microenvironment plays a significant role in tumor progression. Tumor stroma is one of the strongest modifiers of tumor cell response, cancer behavior, and cancer progression. This study aimed to investigate the correlation of matrix metalloproteinase-9 (MMP-9) expression and tumor-stroma ratio (TSR) with standard clinicopathological parameters in different molecular subtypes of breast cancer.Methods: Ninety biopsy samples of primary breast cancer diagnosed at the Department of Pathology, School of Medicine, Sarajevo, were selected for this study. The molecular subtype was determined based on the immunohistochemical expression of estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, and Ki-67. Stromal and tumoral MMP-9 immunohistochemical expression and the TSR were determined for each tumor.Results: Tumoral MMP-9 expression correlated positively with the presence of lymphovascular invasion (p= 0.016). TSR showed significant association and correlation with tumor grade (G) (p= 0.031; p= 0.049) and tumor size (pT) (p = 0.049;p= 0.021, respectively). Stromal MMP-9 expression correlated with histologic type, histologic grade of tumor, and lymphocytic inflammatory infiltrate (p= 0.021;p= 0.047, p= 0.038, respectively). A higher percentage of stromal MMP-9 expression correlated with the strongest lymphocytic response (p = 0.007). Significant correlation was observed between molecular subtypes and histologic grade of the tumor (p= 0.032).Conclusion: Our results, to some extent, confirm the significance of the tumor microenvironment in breast cancer, especially when it is about stromal MMP-9 expression. Although we observed significant association, without linear correlation, we found no significant correlation between molecular subtypes of breast cancer and MMP-9 expression.
{"title":"The relationship of tumor microenvironment and clinico-pathological parameters in different molecular subtypes of breast cancer","authors":"Nina Čamdžić, Suada Kuskunović-Vlahovljak, S. Radović, Mirsad Dorić, M. Babić, Edina Lazović Salčin, A. Spahić","doi":"10.17532/JHSCI.2021.1121","DOIUrl":"https://doi.org/10.17532/JHSCI.2021.1121","url":null,"abstract":"Introduction: Tumor microenvironment plays a significant role in tumor progression. Tumor stroma is one of the strongest modifiers of tumor cell response, cancer behavior, and cancer progression. This study aimed to investigate the correlation of matrix metalloproteinase-9 (MMP-9) expression and tumor-stroma ratio (TSR) with standard clinicopathological parameters in different molecular subtypes of breast cancer.Methods: Ninety biopsy samples of primary breast cancer diagnosed at the Department of Pathology, School of Medicine, Sarajevo, were selected for this study. The molecular subtype was determined based on the immunohistochemical expression of estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, and Ki-67. Stromal and tumoral MMP-9 immunohistochemical expression and the TSR were determined for each tumor.Results: Tumoral MMP-9 expression correlated positively with the presence of lymphovascular invasion (p= 0.016). TSR showed significant association and correlation with tumor grade (G) (p= 0.031; p= 0.049) and tumor size (pT) (p = 0.049;p= 0.021, respectively). Stromal MMP-9 expression correlated with histologic type, histologic grade of tumor, and lymphocytic inflammatory infiltrate (p= 0.021;p= 0.047, p= 0.038, respectively). A higher percentage of stromal MMP-9 expression correlated with the strongest lymphocytic response (p = 0.007). Significant correlation was observed between molecular subtypes and histologic grade of the tumor (p= 0.032).Conclusion: Our results, to some extent, confirm the significance of the tumor microenvironment in breast cancer, especially when it is about stromal MMP-9 expression. Although we observed significant association, without linear correlation, we found no significant correlation between molecular subtypes of breast cancer and MMP-9 expression.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90469579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}