Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P02-06
Daniela Thomazatti Chimello-Sousa, K. Bombonato-Prado, A. Rosa, R. R. Fernandes, L. Bachmann, S. Siéssere, M. Palinkas, Geovane Praxedes Lavez, S. Regalo
AbstractLow-level laser therapy has been investigated as a possible stimulus for enhancement of proliferation and differentiation of various cell types, but few reports relate undifferentiated mouse pulp cells (OD-21) response to irradiation in in vitro models. The aim of this study was to analyze the influence of low-level laser therapy (λ=660 nm), with three different irradiation times, on the behavior of OD-21 cell line. The cells were cultivated and divided into three groups: non-irradiated/control (group I); irradiated with 88 s (group II); irradiated with 177 s (group III) and irradiated with 265 s (group IV). Cell growth and viability were assessed after 7 and 10 days. Data were analyzed by Kruskal-Wallis and Mann-Whitney tests (α=.05). At day 7, there was a higher cell growth in groups I and II, as compared to group IV (p<.01). At the 10th day, group I showed a higher cell growth as compared to group II (p<.05). Cell viability in group IV was significantly lower at the 7th day, as compared to groups I (p<.001), II (p<.01) and III (p<.001). Cell viability in all the groups was over 80%, except in group IV at day 7. Irradiation time of group I influenced positively the proliferation and viability of OD-21 cells in late cell culture period. Keywords: Low-Level Laser Therapy. Cell Culture. Stem Cells. ResumoA terapia a laser de baixa intensidade tem sido investigada como possivel estimulo para aumento da proliferacao e diferenciacao de varios tipos de celulas, mas poucos relatos relacionam a resposta de celulas indiferenciadas da polpa dentaria de camundongos (OD-21) a irradiacao em modelos in vitro. O objetivo deste estudo foi analisar a influencia do laser de baixa intensidade (λ=660 nm), com tres periodos de irradiacao diferentes, no comportamento das celulas da linhagem OD-21. As celulas foram cultivadas e distribuidas em tres grupos: nao irradiado / controle (grupo I); irradiado com 88 s (grupo II); irradiado com 177 s (grupo III) e irradiado com 265 s (grupo IV). O crescimento e a viabilidade celular foram avaliados apos 7 e 10 dias. Os dados foram analisados pelos testes de Kruskal-Wallis e Mann-Whitney (α = 0,05). No dia 7, houve crescimento celular maior nos grupos I e II, em comparacao ao grupo IV (p <0,01). No decimo dia, o grupo I apresentou crescimento celular superior ao grupo II (p <0,05). A viabilidade celular no grupo IV foi significativamente menor no setimo dia, em comparacao aos grupos I (p <0,001), II (p <0,01) e III (p <0,001). A viabilidade celular em todos os grupos foi superior a 80%, exceto no grupo IV no dia 7. O tempo de irradiacao do grupo I influenciou positivamente a proliferacao e a viabilidade das celulas OD-21 no periodo mais tardio da cultura celular. Palavras-chave: Laserterapia de Baixa Intensidade. Cultura Celular. Celulas Tronco.
摘要低水平激光治疗已被研究作为一种可能的刺激来增强各种细胞类型的增殖和分化,但很少有报道将未分化的小鼠牙髓细胞(OD-21)对体外模型的反应联系起来。本研究的目的是分析三种不同照射时间的低强度激光治疗(λ=660 nm)对OD-21细胞系行为的影响。细胞培养后分为三组:未辐照/对照(I组);用88 s照射(II组);177 s (III组)和265 s (IV组)辐照。7天和10天后观察细胞生长和活力。数据采用Kruskal-Wallis检验和Mann-Whitney检验(α= 0.05)。第7天,I组和II组细胞生长高于IV组(p< 0.01)。第10天,I组细胞生长明显高于II组(p< 0.05)。第7天,IV组细胞活力显著低于I组(p< 0.001)、II组(p< 0.01)和III组(p< 0.001)。除IV组7 d外,其余各组细胞存活率均在80%以上。1组辐照时间对OD-21细胞培养后期的增殖和活力有积极影响。关键词:低水平激光治疗;细胞培养。干细胞。在体外研究了激光照射对不同细胞间细胞增殖的影响、不同细胞间细胞间的相互关系、不同细胞间的细胞间的相互关系、不同细胞间的细胞间的相互作用、不同细胞间的细胞间的相互作用、不同细胞间的细胞间的相互作用、不同细胞间的细胞间的相互作用和不同细胞间的相互作用。目的研究激光辐照强度(λ=660 nm)对光谱学的影响,分析光谱学周期与光谱学周期的差异,分析光谱学与光谱学之间的关系。作为有孔细胞栽培,有孔细胞分布在不同的树木组:无辐照/对照(I组);irradiado com 88 s (II组);irradiado com 177s (III组)和irradiado com 265s (IV组). 6个渐增的细胞有孔虫的数量为7至10个。Os dados foram analisados pelos testes de Kruskal-Wallis e Mann-Whitney (α = 0.05)。第7、2、3、4、4组细胞数量均有显著增加(p < 0.01)。I组细胞无明显增厚,I组细胞无明显增厚(p < 0.05)。与I组(p < 0.001)、II组(p < 0.01)和III组(p < 0.001)相比,IV组的存活率显著高于IV组(p < 0.001)。除第4组外,其余3组的存活率均在80%以上。O节奏de irradiacao grupo我influenciou positivamente proliferacao e一viabilidade das中和OD-21没有periodo但是tardio da文化celular。Palavras-chave: Laserterapia de Baixa Intensidade。文化Celular。中和Tronco。
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Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P68-71
José Henrique Nascimento Souza-Junior, André Farias Andrade, L. Volpato, M. Tonetto, Aurélio Rosa da Silva Junior, Bruno Shindi Hirata
AbstractPhotoactivated composite resins are among the most widespread restorative materials in dentistry, particularly in cosmetic dentistry. To obtain the best properties of the material, the resins must have their polymerization reaction initiated by means of the light-curing device, which activates the photoinitiators present in the composites. For this process to occur in the desired way, it is essential that the light-curing device emits light at the intensity necessary to properly activate the photoinitiators. Thus, a pilot study was carried out to assess the light intensity emitted by the light-curing devices used in a school clinic. To assess the light intensity emitted by the devices, a radiometer was used. Twenty-four light-curing devices were evaluated, 13 Optilight Max devices, 8 Optilight LD MAX 440 devices, 3 Emitter C. devices. All the devices had an emitted light below 400 mW / cm² and 67% of the devices had intensity above 300 mW/cm². The average light emission values of the light-curing devices were Optilight Max 334mW/cm², Emitter C 275mW/cm², Optilight LD MAX 440 296mW/cm². It was concluded that no light-curing device emitted light at the recommended intensity (400 mW/cm²), two thirds of the devices emitted light in intensity above the minimum required for photopolymerization of composite resin increments of up to 2mm and one third emitted light in intensity below the required minimum. There was no difference among the light-curing device models tested in this study. Keywords: Photoinitiators, Dental. Dental. Tooth. Composite Resins. ResumoAs resinas compostas fotoativadas estao entre os materiais restauradores mais difundidos em odontologia, particularmente na odontologia estetica. Para obtencao das melhores propriedades do material, as resinas precisam ter sua reacao de polimerizacao iniciada por meio do fotopolimerizador, que ativa os fotoiniciadores presentes nos compositos. Para que esse processo ocorra da forma desejada, e fundamental que o fotopolimerizador emita a luz na intensidade necessaria para ativar adequadamente os fotoiniciadores. Assim, foi realizado um estudo piloto para avaliadar a intensidade da luz emitida pelo fotopolimerizadores utilizados em uma clinica-escola. Para avaliar a intensidade da luz emitida pelos dispositivos, foi utilizado um radiometro. Vinte e quatro fotopolimerizadores foram avaliados, 13 aparelhos Optilight Max, 8 aparelhos Optilight LD MAX 440, 3 aparelhos Emitter C. Todos os dispositivos tiveram a luz emitida em intensidade inferior a 400 mW/cm² e 67% dos dispositivos apresentaram intensidade acima de 300 mW/cm². As medias de valores de emissao de luz dos fotopolimerizadores foram, Optilight Max 334mW/cm², Emitter C 275mW/cm², Optilight LD MAX 440 296mW/cm²Concluiu-se que nenhum fotopolimerizador emitiu luz na intensidade recomendada (400 mW/cm²), dois tercos dos aparelhos emitiram luz em intensidade acima da minima necessaria para fotopolimerizacao de incrementos de resina composta
摘要光活化复合树脂是目前应用最广泛的牙科修复材料之一,特别是在牙科美容方面。为了获得材料的最佳性能,树脂必须通过光固化装置引发聚合反应,光固化装置激活复合材料中的光引发剂。为了使该过程以期望的方式发生,光固化装置必须以适当激活光引发剂所需的强度发射光。因此,进行了一项试点研究,以评估学校诊所使用的光固化设备发出的光强度。为了评估设备发出的光强度,使用了辐射计。共评估了24个光固化器件,其中13个为Optilight Max器件,8个为Optilight LD Max 440器件,3个为Emitter c器件。所有器件的发射光强度均低于400 mW/cm²,67%的器件的发射光强度高于300 mW/cm²。光固化器件的平均光发射值为Optilight Max 334mW/cm²,Emitter C 275mW/cm²,Optilight LD Max 440 296mW/cm²。结果表明,没有光固化器件发出的光强度达到推荐强度(400mw /cm²),三分之二的器件发出的光强度高于复合树脂光聚合所需的最小值,增量高达2mm,三分之一的器件发出的光强度低于所需的最小值。在本研究中测试的光固化器件模型之间没有差异。关键词:光引发剂;牙科;牙科。牙齿。复合树脂。摘要树脂复合材料在牙科学,特别是牙科学的研究中具有重要的应用价值。Para obtencao和melhores专有的聚合物材料,如树脂的精密度、聚合速率、聚合速率、聚合速率、聚合速率、聚合速率、聚合速率、聚合速率、聚合速率、聚合速率、聚合速率等。Para - esse process (Para - esse process, Para - esse process, corcora da forma desejada)是一项基本的技术,它可以促进必要的Para - esse充分发展。同时,本文还提出了一种新的方法,即在临床应用中,在临床应用中,在临床应用中,在临床应用中,在临床应用中,在临床应用中,在临床应用中,在临床应用中应用。Para avaliar a intensidade da luz emitida pelos dispositivos, foi utilization um radiometro。Vinte e四弦吉他fotopolimerizadores有孔虫avaliados 13 aparelhos Optilight马克斯,8 aparelhos Optilight LD Max 440年3 aparelhos发射器c Todos os dispositivos tiveram luz emitida em intensidade劣质400 mW / cm²e 67% dos dispositivos apresentaram intensidade acima²300 mW /厘米。作为介质,Optilight Max为334mW/cm²,Emitter C为275mW/cm²,Optilight LD Max为440 296mW/cm²。结论:Optilight Max为400mw /cm²,Optilight Max为400mw /cm²,Optilight Max为400mw /cm²,Optilight Max为400mw /cm²,Optilight Max为400mw /cm²,Optilight Max为400mw /cm²,Optilight Max为400mw /cm²,Optilight light Max为400mw /cm²,Optilight light light Max为400mw /cm²,Optilight light light Max为400mw /cm²。没有人有不同的研究中心,他们的模型是关于生物聚合的,他们的模型是关于生物聚合的。palavras - have: fotoiniciados Dentarios。变硬。Resinas Compostas。
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Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P47-50
M. C. Vieira, E. A. Gomes, E. Montero
AbstractOvarian graft may be the target of the biochemical effects of oxidative stress caused at the time of transplantation. In order to evaluate the effect of N-acetylcysteine on the ovarian graft, regarding the estrous cycle preservation , 50 female and virgin EPM-1 Wistar rats, weighing up to 250g, originating from CEDEME of UNIFESP, were kept in adequate sanitary conditions. , receiving their own food and water. Daily vaginal smears were performed to identify the estrous phase for 8 days. The animals were randomly distributed into 05 groups: 1st Group (GTx), saline was administered subcutaneously, 2nd (NAC 150mgKg), 3rd (NAC 300mg / Kg), 4th (NAC 600mg / Kg) and 5th (NAC 1200mg / Kg) , that were administered NAC subcutaneously on the abdominal face, 60 minutes before left unilateral ovarian transplantation in retroperitoneum and contralateral oophorectomy for purposes of histomorphological analysis, with colpocytological evaluation. Euthanasia was performed by means of anesthetic lethal dose in half of the animals on the 4th postoperative day, with a single vaginal smear collection and euthanasia on the rest of the animals, between the 14th and 16th days, after the material was collected in order to define the estrus phase. It was evaluated in the graft that the animals exhibited in all groups return of estrous cycle in the later phase of the post-transplant, with better definition of regular cycle in the highest dosages of N-acetylcysteine. N-acetylcysteine induced the return of the estrous cycle in the rats’ ovarian graft , mainly in the highest dosage, proving its effectiveness in revascularization of the tissue after ischemia and reperfusion. Keywords: Acetylcysteine. Reperfusion. Histocompatibility Antigens. Menstrual Cycle. ResumoO enxerto ovariano pode ser alvo dos efeitos bioquimicos do stress oxidativo causado no momento do transplante. Com o objetivo de avaliar o efeito da N-acetilcisteina no enxerto ovariano, quanto a preservacao do ciclo estral, foram utilizados 50 ratos EPM-1 Wistar, femeas e virgens, pesando ate 250g, originarios do CEDEME da UNIFESP, mantidos em adequadas condicoes sanitarias, recebendo racao propria e agua. Realizados esfregacos vaginais diarios para identificacao da fase estral durante 08 dias. Os animais foram distribuidos aleatoriamente em 05 grupos: 1o Grupo (GTx), administrada solucao salina via subcutânea, 2o (NAC 150mgKg), 3o (NAC 300mg/Kg), 4o (NAC 600mg/Kg) e 5o (NAC 1200mg/Kg), aos quais foi administrada NAC por via subcutânea em face abdominal, 60 minutos antes do transplante unilateral esquerdo do ovario em retroperitonio e a ooforectomia contra-lateral para fins de analise histomorfologica, com avaliacao colpocitologica. A eutanasia foi realizada por meio da dose letal do anestesico em metade dos animais no 4o dia de pos-operatorio, realizado unica coleta de esfregaco vaginal e a eutanasia no restante dos animais, entre o 14 o e 16o dia, apos a coleta do material para definicao da fase estro. F
{"title":"The Study of Estrous Cycle Phases Female Rats With the Use of N-Acetylcysteine in Ovarian Graft","authors":"M. C. Vieira, E. A. Gomes, E. Montero","doi":"10.17921/2447-8938.2021V23N1P47-50","DOIUrl":"https://doi.org/10.17921/2447-8938.2021V23N1P47-50","url":null,"abstract":"AbstractOvarian graft may be the target of the biochemical effects of oxidative stress caused at the time of transplantation. In order to evaluate the effect of N-acetylcysteine on the ovarian graft, regarding the estrous cycle preservation , 50 female and virgin EPM-1 Wistar rats, weighing up to 250g, originating from CEDEME of UNIFESP, were kept in adequate sanitary conditions. , receiving their own food and water. Daily vaginal smears were performed to identify the estrous phase for 8 days. The animals were randomly distributed into 05 groups: 1st Group (GTx), saline was administered subcutaneously, 2nd (NAC 150mgKg), 3rd (NAC 300mg / Kg), 4th (NAC 600mg / Kg) and 5th (NAC 1200mg / Kg) , that were administered NAC subcutaneously on the abdominal face, 60 minutes before left unilateral ovarian transplantation in retroperitoneum and contralateral oophorectomy for purposes of histomorphological analysis, with colpocytological evaluation. Euthanasia was performed by means of anesthetic lethal dose in half of the animals on the 4th postoperative day, with a single vaginal smear collection and euthanasia on the rest of the animals, between the 14th and 16th days, after the material was collected in order to define the estrus phase. It was evaluated in the graft that the animals exhibited in all groups return of estrous cycle in the later phase of the post-transplant, with better definition of regular cycle in the highest dosages of N-acetylcysteine. N-acetylcysteine induced the return of the estrous cycle in the rats’ ovarian graft , mainly in the highest dosage, proving its effectiveness in revascularization of the tissue after ischemia and reperfusion. \u0000Keywords: Acetylcysteine. Reperfusion. Histocompatibility Antigens. Menstrual Cycle. \u0000ResumoO enxerto ovariano pode ser alvo dos efeitos bioquimicos do stress oxidativo causado no momento do transplante. Com o objetivo de avaliar o efeito da N-acetilcisteina no enxerto ovariano, quanto a preservacao do ciclo estral, foram utilizados 50 ratos EPM-1 Wistar, femeas e virgens, pesando ate 250g, originarios do CEDEME da UNIFESP, mantidos em adequadas condicoes sanitarias, recebendo racao propria e agua. Realizados esfregacos vaginais diarios para identificacao da fase estral durante 08 dias. Os animais foram distribuidos aleatoriamente em 05 grupos: 1o Grupo (GTx), administrada solucao salina via subcutânea, 2o (NAC 150mgKg), 3o (NAC 300mg/Kg), 4o (NAC 600mg/Kg) e 5o (NAC 1200mg/Kg), aos quais foi administrada NAC por via subcutânea em face abdominal, 60 minutos antes do transplante unilateral esquerdo do ovario em retroperitonio e a ooforectomia contra-lateral para fins de analise histomorfologica, com avaliacao colpocitologica. A eutanasia foi realizada por meio da dose letal do anestesico em metade dos animais no 4o dia de pos-operatorio, realizado unica coleta de esfregaco vaginal e a eutanasia no restante dos animais, entre o 14 o e 16o dia, apos a coleta do material para definicao da fase estro. F","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"29 1","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79218583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P25-29
F. Jassé, C. Alencar, Natália Fernandes Pollo, C. Silva, E. Campos
AbstractThe teeth weakening due to the preparation of class II mesio-occluso-distal cavities is a challenge for the clinician. The objective of this study was to evaluate the molars fracture resistance with class II mesio-occluso-distal cavities restored with different restorative techniques and materials. Forty extracted molars were divided into 5 groups: Group 1 – intact healthy teeth (positive control); Group 2 – unrestored teeth with mesio-occluso-distal class II cavities (negative control); Groups 3 to 5 – restored teeth with standardized dimensions. In groups 3 to 5, the cavities were restored with flow resin only, flow resin coated with a nano-hybrid resin, and nano-hybrid resin only, respectively. All specimens were tested for resistance to fracture using an axial compressive load, a metallic sphere measuring 8 mm in diameter on a universal testing machine EMIC DL-2000. A 10 kN load cell operated at a speed of 5 mm/min until the tooth fracture. Data were subjected to analysis of variance and Tukey’s tests (α = 0.05). Group 3 showed higher fracture strength (2243.1 ± 473.7N) when compared to groups 2, 4 and 5. This difference was statistically significant (p<0.05). The fracture strength of teeth restored with flow mesio-occluso-distal restorations was similar to that of intact natural teeth. Keywords: Compressive Strength. Composite Resins. Dental Cavity Preparation. ResumoO enfraquecimento dos dentes devido as preparacoes de cavidades mesio-ocluso-distal e um desafio para o clinico. O objetivo deste estudo foi avaliar a resistencia a fratura de molares com cavidades mesio-ocluso-distais classe II restauradas com diferentes tecnicas e materiais restauradores. Quarenta molares extraidos foram divididos em 5 grupos: Grupo 1 – dentes saudaveis intactos (controle positivo); Grupo 2 – dentes nao restaurados com cavidades mesio-occluso-distais classe II (controle negativo); Grupos 3 a 5 – dentes restaurados com dimensoes padronizadas. Nos grupos 3 a 5, as cavidades foram restauradas apenas com resina flow, resina flow recoberta com uma resina nano-hibrida e somente resina nano-hibrida, respectivamente. Todas as amostras foram testadas quanto a resistencia a fratura usando uma carga compressiva axial, usando uma esfera metalica medindo 8 mm de diâmetro em uma maquina de teste universal EMIC DL-2000. Uma celula de carga de 10 kN operava a uma velocidade de 5 mm/min ate a fratura do dente. Os dados foram submetidos a analise de variância e testes de Tukey (α = 0,05). O grupo 3 apresentou maior resistencia a fratura (2243,1 ± 473,7N) quando comparado aos grupos 2, 4 e 5. Essa diferenca foi estatisticamente significante (p <0,05). A resistencia a fratura dos dentes restaurados com resina flow foi semelhante a dos dentes naturais intactos. Keywords: Forca Compressiva. Resinas Compostas. Preparo da Cavidade Dentaria.
摘要ⅱ类中牙合远端牙体的制备导致的牙齿弱化是临床医师面临的一个挑战。本研究的目的是评估采用不同修复技术和材料修复的II类中牙合远端牙洞对磨牙骨折的抵抗性。40颗拔除的磨牙分为5组:1组为完整健康牙(阳性对照);2组:未修复的中牙合远端II类蛀牙(阴性对照);第3组至第5组:尺寸标准化的修复牙齿。第3 ~ 5组分别采用流动树脂、流动树脂包覆纳米复合树脂和纳米复合树脂修复空腔。在万能试验机EMIC DL-2000上,用直径为8毫米的金属球体进行轴向压缩载荷抗断裂测试。一个10 kN的称重传感器以5毫米/分钟的速度运行,直到牙齿断裂。数据进行方差分析和Tukey检验(α = 0.05)。3组的断裂强度(2243.1±473.7N)高于2、4、5组。差异有统计学意义(p<0.05)。流动中牙合远端修复体修复牙体的断裂强度与天然完整牙体相似。关键词:抗压强度;复合树脂。口腔准备。目的:探讨临床中、近端、远端牙槽骨缺损的修复方法。目的研究不同工艺和材料条件下,中高档高档二级餐厅室内装饰材料的抗腐蚀性能。5组:1组:牙齿发育完整(阳性对照);Grupo 2 -齿nao restaurados com cavidades mesio-occluso-distais架势II (controle negativo);第3组和第5组的餐厅都有自己的空间。第3、5组分别为孔洞、孔洞、孔洞、孔洞、孔洞、孔洞、孔洞、孔洞、孔洞、孔洞、孔洞、孔洞、孔洞。今天,作为amostras foram testadas quanto a resistance a fratura usando uma carga压缩轴向,usando uma esfera metalica medindo 8 mm de dialma metro em uma maquina de teste通用EMIC DL-2000。在10 kN的操作条件下,在5 mm/min的速度下,在自然咬合条件下,形成一个裂口。Os dados foram submetidos a analise de varia ncia e testes de Tukey (α = 0.05)。与2、4、5组相比,3组出现了主要的自然抗性(2243,1±473,7N)。差异有统计学意义(p < 0.05)。自然的阻力和自然的阻力在半自然状态下的流动和自然状态下的流动是一致的。关键词:力压缩;Resinas Compostas。预备预备龋洞。
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Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P12-17
D. Castro, A. B. V. Teixeira, O. L. Alves, A. Reis
AbstractThe acrylic resin used for the prosthesis base accumulates biofilm, causing diseases such as stomatitis. The addition of some nanoparticles promotes antimicrobial action. This study incorporated the nanostructured silver vanadate decorated with silver nanoparticles (AgVO3) to the acrylic resin by two methods and evaluated the cytotoxicity for human gingival fibroblasts (HGF) and the released silver and vanadium ions. The concentrations of 0.5, 1, 2.5, and 5% of AgVO3 was incorporated by vacuum spatulation and polymeric film. The vacuum spatulation was performed for 60 s using the Turbomix equipment, and the polymeric film was obtained from the polymer solubilization in chloroform, the film was subjected to a cryogenic grinding, and the powder obtained was manually mixed at the monomer. HGF cell viability was assessed after 24 hours, 7 and 14 days by the MTT assay. The release of silver (Ag) and vanadium (V) ions were quantified by inductively coupled plasma mass spectrometry after 30 days. Kruskal-Wallis and Dunn’s test were applied (α = 0.05). The HGF viability was inversely proportional to the incubation time. Both incorporation techniques and the negative and positive control groups presented significant statistical differences (p 0.05), except the vacuum spatulation group with 5% of AgVO3 that showed greater viability than the negative control (p=0.013) in 24 hours. The release of Ag and V ions was proportional to the concentration of AgVO3 The 5% group presented a significant difference compared to the other groups (p<0.05). In conclusion, the acrylic resin with and without the AgVO3 incorporation had a small cytotoxic potential for HGF in 24 hours, with a lower viability in longer contact times; the release of Ag and V ions was proportional to the concentration of AgVO3, not influencing cell viability. Keywords: Acrylic Resins. Cell Survival. Nanotechnology. Ions. ResumoA resina acrilica utilizada para a base da protese acumula biofilme, causando doencas como a estomatite. A adicao de algumas nanoparticulas promove acao antimicrobiana. Este estudo incorporou o vanadato de prata nanoestruturado decorado com nanoparticulas de prata (AgVO3) a resina acrilica por dois metodos e avaliou a citotoxicidade para fibroblastos gengivais humanos (HGF) e os ions prata e vanadio liberados. As concentracoes de 0,5%, 1%, 2,5% e 5% de AgVO3 foram incorporadas por espatulacao a vacuo e filme polimerico. A espatulacao a vacuo foi realizada por 60 s no equipamento Turbomix, e o filme polimerico foi obtido a partir da solubilizacao do polimero em cloroformio, o filme foi submetido a uma moagem criogenica e o po obtido foi misturado manualmente ao monomero. A viabilidade celular de HGF foi avaliada apos 24 horas, 7 e 14 dias pelo ensaio de MTT. A liberacao de ions prata (Ag) e vanadio (V) foi quantificada por espectrometria de massa com plasma indutivamente acoplado apos 30 dias. Os testes de Kruskal-Wallis e Dunn foram aplicados (α=0,05). A viabilidad
摘要用于修复体底座的丙烯酸树脂会积累生物膜,引起口腔炎等疾病。添加一些纳米颗粒可以促进抗菌作用。本研究通过两种方法将银纳米粒子修饰的纳米结构钒酸银(AgVO3)加入丙烯酸树脂中,并对其对人牙龈成纤维细胞(HGF)的细胞毒性及释放的银和钒离子进行了评价。分别以0.5、1、2.5和5%浓度的AgVO3通过真空搅拌和聚合膜掺入。在Turbomix设备上进行真空搅拌60 s,将聚合物在氯仿中增溶得到聚合物膜,对聚合物膜进行低温研磨,并在单体上手动混合得到的粉末。24小时、7天和14天后,采用MTT法测定HGF细胞活力。30天后用电感耦合等离子体质谱法测定银(Ag)和钒(V)离子的释放。采用Kruskal-Wallis和Dunn检验(α = 0.05)。HGF活力与孵育时间成反比。除真空挤压5% AgVO3组24小时存活率高于阴性对照组(p=0.013)外,阴性对照组和阴性对照组的存活率均有统计学差异(p < 0.05)。Ag、V离子释放量与AgVO3浓度成正比,5%组与其他组比较差异有统计学意义(p<0.05)。综上所述,含AgVO3和未含AgVO3的丙烯酸树脂在24小时内对HGF具有较小的细胞毒性,接触时间越长,活性越低;Ag和V离子的释放与AgVO3浓度成正比,不影响细胞活力。关键词:丙烯酸树脂;细胞的生存。纳米技术。离子。还原树脂的利用是一种基于蛋白质积累的生物膜、原因和结构的合成材料。一种海藻纳米颗粒促进抗菌素的产生。采用纳米结构、纳米颗粒、纳米结构、纳米颗粒、纳米结构、纳米颗粒、纳米结构、纳米结构、纳米颗粒、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构、纳米结构。当AgVO3的浓度分别为0.5%、1%、2.5%、5%和5%时,可获得较好的真空膜聚合物。一个真空espatulacao信息自由realizada为什么60年代没有equipamento Turbomix, e o filme polimerico信息自由obtido从da solubilizacao polimero em cloroformio, o filme信息自由submetido乌玛moagem criogenica e o阿宝obtido信息自由misturado manualmente ao monomero。HGF细胞可存活24小时,7小时,14小时。用定量差谱法研究了等离子体等离子体诱导等离子体在30个介质中的作用。Os testes de Kruskal-Wallis e Dunn foram应用者(α= 0.05)。HGF的可行性与投资成正比。随着技术的纳入,各组控制性阴性阳性表现差异有统计学意义(p < 0.05),除控制性阴性表现为5%的AgVO3组外,其余24组控制性阴性表现为主要阳性表现(p < 0.05)。AgVO3的浓度与AgVO3的浓度成正比。0组(5%)与正常组比较差异有统计学意义(p < 0.05)。综上所述,在HGF的24小时内,AgVO3的浓度可能与HGF的潜在毒性有关,而AgVO3的浓度与HGF的潜在毒性无关,AgVO3的浓度与HGF的潜在毒性无关,AgVO3的浓度与HGF的潜在毒性无关。palavras - have: Resinas acrilica。Sobrevivencia Celular。Nanotecnologia。离子。
{"title":"Cytotoxicity and Elemental Release of Dental Acrylic Resin Modified with Silver and Vanadium Based Antimicrobial Nanomaterial","authors":"D. Castro, A. B. V. Teixeira, O. L. Alves, A. Reis","doi":"10.17921/2447-8938.2021V23N1P12-17","DOIUrl":"https://doi.org/10.17921/2447-8938.2021V23N1P12-17","url":null,"abstract":"AbstractThe acrylic resin used for the prosthesis base accumulates biofilm, causing diseases such as stomatitis. The addition of some nanoparticles promotes antimicrobial action. This study incorporated the nanostructured silver vanadate decorated with silver nanoparticles (AgVO3) to the acrylic resin by two methods and evaluated the cytotoxicity for human gingival fibroblasts (HGF) and the released silver and vanadium ions. The concentrations of 0.5, 1, 2.5, and 5% of AgVO3 was incorporated by vacuum spatulation and polymeric film. The vacuum spatulation was performed for 60 s using the Turbomix equipment, and the polymeric film was obtained from the polymer solubilization in chloroform, the film was subjected to a cryogenic grinding, and the powder obtained was manually mixed at the monomer. HGF cell viability was assessed after 24 hours, 7 and 14 days by the MTT assay. The release of silver (Ag) and vanadium (V) ions were quantified by inductively coupled plasma mass spectrometry after 30 days. Kruskal-Wallis and Dunn’s test were applied (α = 0.05). The HGF viability was inversely proportional to the incubation time. Both incorporation techniques and the negative and positive control groups presented significant statistical differences (p 0.05), except the vacuum spatulation group with 5% of AgVO3 that showed greater viability than the negative control (p=0.013) in 24 hours. The release of Ag and V ions was proportional to the concentration of AgVO3 The 5% group presented a significant difference compared to the other groups (p<0.05). In conclusion, the acrylic resin with and without the AgVO3 incorporation had a small cytotoxic potential for HGF in 24 hours, with a lower viability in longer contact times; the release of Ag and V ions was proportional to the concentration of AgVO3, not influencing cell viability. \u0000Keywords: Acrylic Resins. Cell Survival. Nanotechnology. Ions. \u0000ResumoA resina acrilica utilizada para a base da protese acumula biofilme, causando doencas como a estomatite. A adicao de algumas nanoparticulas promove acao antimicrobiana. Este estudo incorporou o vanadato de prata nanoestruturado decorado com nanoparticulas de prata (AgVO3) a resina acrilica por dois metodos e avaliou a citotoxicidade para fibroblastos gengivais humanos (HGF) e os ions prata e vanadio liberados. As concentracoes de 0,5%, 1%, 2,5% e 5% de AgVO3 foram incorporadas por espatulacao a vacuo e filme polimerico. A espatulacao a vacuo foi realizada por 60 s no equipamento Turbomix, e o filme polimerico foi obtido a partir da solubilizacao do polimero em cloroformio, o filme foi submetido a uma moagem criogenica e o po obtido foi misturado manualmente ao monomero. A viabilidade celular de HGF foi avaliada apos 24 horas, 7 e 14 dias pelo ensaio de MTT. A liberacao de ions prata (Ag) e vanadio (V) foi quantificada por espectrometria de massa com plasma indutivamente acoplado apos 30 dias. Os testes de Kruskal-Wallis e Dunn foram aplicados (α=0,05). A viabilidad","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"63 1","pages":"12-17"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86822893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P62-67
D. Guimarães, A. Mello, Hellen Daniela de Sousa Coelho
AbstractCommunity Health Agents (CHAs) are important collaborators in combating illnesses related to poor eating habits. The objective of this work was to verify the knowledge of the community health workers of Cajamar city about food and the main diseases related to bad eating habits. This is a cross-sectional study, conducted from August to September 2011, in Cajamar city, Sao Paulo by trained interviewers. 57 HCWs were interviewed who answered two questionnaires, the first to characterize them and the second to obtain data on basic knowledge about food and the main diseases related to poor eating habits. 96.5% of the CHA were female, had an average of 34 years, 88.1% had two children, predominance of complete high school (56.1%; n=32). They had the function of CHAs as the main source of income, receiving up to three minimum wages and exercising it for at least six months (52.6%). When the subject was food, 94.5% report that they are the first to address the issue. The main difficulties were that people did not follow the guidelines (43%) and lack of knowledge (40%). There was a good performance in the issues regarding chronic diseases (76.6% of hits) and risk groups (97%). In questions about food groups and food security, there was low performance (rate of hits of 55.2% and 55.3%, respectively). The qualification of CSAs is fundamental for the improvement of the work performed, being important the use of educational strategies that provide continuous learning. Keywords: Community Health Workers. Food Assistance. Family Health Strategy. Primary Health Care. ResumoOs Agentes Comunitarios de Saude (ACS) sao importantes colaboradores no combate de doencas relacionadas aos maus habitos alimentares. O objetivo deste trabalho foi verificar o conhecimento dos ACS do municipio de Cajamar sobre alimentacao e as principais doencas relacionadas aos maus habitos alimentares. Trata-se de um estudo transversal, realizado no periodo de agosto a setembro de 2011, no municipio de Cajamar, Sao Paulo por entrevistadores treinados. Foram entrevistados 57 ACS que responderam a dois questionarios, o primeiro com intuito de caracteriza-los e o segundo para obter dados quanto aos conhecimentos basicos sobre alimentacao e as principais doencas relacionadas aos maus habitos alimentares. 96,5% dos ACS eram do sexo feminino, possuiam em media 34 anos, 88,1% possuiam dois filhos, predominância de ensino medio completo (56,1%; n=32). Possuiam a funcao de ACS como principal fonte de renda, recebendo ate tres salarios minimos e exercendo-a ha pelo menos seis meses (52,6%). Quando o assunto foi alimentacao, 94,5% relatam que sao os primeiros a abordar o assunto. As principais dificuldades encontradas foram que as pessoas nao seguem as orientacoes (43%) e a falta de conhecimentos (40%). Verificou-se bom desempenho nas questoes que se referiam as doencas cronicas (76,6% de acertos) e grupos de risco (97%). Ja nas questoes sobre grupos alimentares e seguranca alimentar, houve b
摘要社区健康代理人(CHAs)是与不良饮食习惯相关疾病作斗争的重要合作者。这项工作的目的是验证卡哈马尔市社区卫生工作者对食物和与不良饮食习惯有关的主要疾病的了解。这是一项横断面研究,于2011年8月至9月在圣保罗卡哈玛市由训练有素的采访者进行。对57名卫生保健员进行了访谈,他们回答了两份问卷,第一份问卷是为了描述他们的特点,第二份问卷是为了获取有关食物的基本知识和与不良饮食习惯有关的主要疾病的数据。96.5%的CHA为女性,平均年龄34岁,88.1%的CHA有两个孩子,高中学历占56.1%;n = 32)。他们的主要收入来源是社区福利机构的职能,领取最多三份最低工资,并至少执行六个月(52.6%)。当话题是食物时,94.5%的人报告说他们是第一个解决这个问题的人。主要的困难是人们没有遵循指南(43%)和缺乏知识(40%)。在慢性病(76.6%)和危险群体(97%)问题上表现良好。在关于食品类别和食品安全的问题上,表现不佳(命中率分别为55.2%和55.3%)。csa的资格是改进所做工作的基础,对于使用提供持续学习的教育策略很重要。关键词:社区卫生工作者;食品援助。家庭保健战略。初级卫生保健。沙特联合机构(ACS)是一项重要的合作伙伴,它没有与其他主要习惯和食物的关系进行斗争。前言:目的:对《卡哈马市食品安全公约》的执行情况进行核查,并将其作为主要研究对象,探讨其与主要习惯食品的关系。Trata-se de um estudo transversale, realizado no periodo de agosto a setembro de 2011, no municipio de Cajamar, Sao Paulo povistadores treinados。有孔企业家对57个ACS的应答者进行了问卷调查,并对其进行了初步的直观特征描述,对其进行了第二阶段的调查,对其进行了初步的分析,对其进行了初步的分析,对其进行了初步的分析,并将其作为主要的研究对象,对其进行了关系分析,对其进行了主要的习惯分析。96,5%的人有女性性取向,34岁以上的人有男性性取向,88,1%的人有男性性取向,主要是美国女性性取向(56,1%);n = 32)。Possuiam是一种功能,即ACS的主要功能(como principal fonte de renda),即最低限度的工资,即最低限度的工资,即最低限度的工资(52.6%)。在全国范围内,约有94,5%的人口是主要人口。作为原则的困难是矛盾的,因为有原则的困难是矛盾的,因为有原则的困难是矛盾的(43%),因为有原则的困难是矛盾的(40%)。验证性出生问卷调查的问卷调查结果显示,问卷调查结果与调查结果一致(76.6%),与调查结果一致(97%)。这两个问题分别是:食品质量、食品质量、食品质量和食品质量(食品质量指数分别为55.2%和55.3%)。能力是最重要的,最基本的,最基本的,最基本的,最基本的,最基本的,最基本的,最基本的,最基本的,最基本的,最基本的。Palavras-chave:沙特政府。Assistencia Alimentar。沙特家族战略。Atencao primary a saudi
{"title":"Profile and Knowledge of Community Health Agents (CHAS) of Cajamar City, Brazil","authors":"D. Guimarães, A. Mello, Hellen Daniela de Sousa Coelho","doi":"10.17921/2447-8938.2021V23N1P62-67","DOIUrl":"https://doi.org/10.17921/2447-8938.2021V23N1P62-67","url":null,"abstract":"AbstractCommunity Health Agents (CHAs) are important collaborators in combating illnesses related to poor eating habits. The objective of this work was to verify the knowledge of the community health workers of Cajamar city about food and the main diseases related to bad eating habits. This is a cross-sectional study, conducted from August to September 2011, in Cajamar city, Sao Paulo by trained interviewers. 57 HCWs were interviewed who answered two questionnaires, the first to characterize them and the second to obtain data on basic knowledge about food and the main diseases related to poor eating habits. 96.5% of the CHA were female, had an average of 34 years, 88.1% had two children, predominance of complete high school (56.1%; n=32). They had the function of CHAs as the main source of income, receiving up to three minimum wages and exercising it for at least six months (52.6%). When the subject was food, 94.5% report that they are the first to address the issue. The main difficulties were that people did not follow the guidelines (43%) and lack of knowledge (40%). There was a good performance in the issues regarding chronic diseases (76.6% of hits) and risk groups (97%). In questions about food groups and food security, there was low performance (rate of hits of 55.2% and 55.3%, respectively). The qualification of CSAs is fundamental for the improvement of the work performed, being important the use of educational strategies that provide continuous learning. \u0000Keywords: Community Health Workers. Food Assistance. Family Health Strategy. Primary Health Care. \u0000ResumoOs Agentes Comunitarios de Saude (ACS) sao importantes colaboradores no combate de doencas relacionadas aos maus habitos alimentares. O objetivo deste trabalho foi verificar o conhecimento dos ACS do municipio de Cajamar sobre alimentacao e as principais doencas relacionadas aos maus habitos alimentares. Trata-se de um estudo transversal, realizado no periodo de agosto a setembro de 2011, no municipio de Cajamar, Sao Paulo por entrevistadores treinados. Foram entrevistados 57 ACS que responderam a dois questionarios, o primeiro com intuito de caracteriza-los e o segundo para obter dados quanto aos conhecimentos basicos sobre alimentacao e as principais doencas relacionadas aos maus habitos alimentares. 96,5% dos ACS eram do sexo feminino, possuiam em media 34 anos, 88,1% possuiam dois filhos, predominância de ensino medio completo (56,1%; n=32). Possuiam a funcao de ACS como principal fonte de renda, recebendo ate tres salarios minimos e exercendo-a ha pelo menos seis meses (52,6%). Quando o assunto foi alimentacao, 94,5% relatam que sao os primeiros a abordar o assunto. As principais dificuldades encontradas foram que as pessoas nao seguem as orientacoes (43%) e a falta de conhecimentos (40%). Verificou-se bom desempenho nas questoes que se referiam as doencas cronicas (76,6% de acertos) e grupos de risco (97%). Ja nas questoes sobre grupos alimentares e seguranca alimentar, houve b","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"6 1","pages":"62-67"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74588730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P35-38
R. Pereira Pinto, D. M. D. Oliveira, Anderson Geremias Macedo, Giselle Soares Passos
AbstractClimacteric is a natural process characterized by the female hormones reduction and increased symptoms that interfere in the woman's quality of life. The objective was to raise scientific evidence on the physical exercise effects as a therapeutic strategy on climacteric symptoms. This systematic review study accessed the Virtual Health Library (VHL) and consulted articles from the last 10 years, with the following eligibility criteria; inclusion, scientific articles published in the last 10 years, with clinical, quasi-experimental, cross-sectional design and case studies conducted with women in the climacteric. Articles published before 2010 with delineations were excluded; epidemiological, systematic review, meta-analyzes, experimental studies with animal model. The studies included in the review were read in full, critically analyzed and categorized. The findings showed that active women have a reduction in vasomotor and somatic symptoms of the climacteric, also collaborating in the prevention of diseases prevalent in this period. Aerobic physical exercise improves physical fitness and quality of life indicators of climacteric women. In clinical practice, aerobic exercise can be considered an auxiliary strategy in the climacteric symptoms treatment and female health improvement. Keywords: Climacteric. Health. Physical Exercise. ResumoO climaterio e um processo natural caracterizado pela reducao dos hormonios femininos e aumento de sintomas que interferem na qualidade de vida da mulher. Objetivou-se levantar evidencias cientificas sobre os efeitos do exercicio fisico como estrategia terapeutica na sintomatologia climaterica. Este estudo de revisao sistematica acessou a Biblioteca Virtual de Saude (BVS) e consultou artigo dos ultimos 10 anos, com os seguintes criterios de elegibilidade; inclusao, artigos cientificos com delineamento clinico, quase-experimental, transversal e estudos de caso realizados com mulheres no climaterio. Foram excluidos artigos publicados anterior a 2010, com delineamentos; epidemiologico, revisao sistematica, metanalises, estudos experimentais com modelo animal. Os estudos incluidos na revisao foram lidos na integra, analisados criticamente e categorizados. Os achados demonstraram que mulheres ativas apresentam reducao dos sintomas vasomotores e somaticos do climaterio, tambem colabora na prevencao de doencas prevalentes nesse periodo. O exercicio fisico aerobio melhora a aptidao fisica e indicadores de qualidade de vida de mulheres climatericas. Na pratica clinica o exercicio aerobio pode ser considerado uma estrategia auxiliar no tratamento dos sintomas do climaterio e melhora da saude feminina. Palavras-chave: Climaterio. Saude. Exercicio Fisico.
摘要更年期是一个以女性荷尔蒙减少和症状增加为特征的自然过程,影响女性的生活质量。目的是为体育锻炼作为更年期症状治疗策略的效果提供科学证据。本系统评价研究访问了虚拟健康图书馆(VHL),并参考了近10年来的文章,符合以下资格标准;纳入近十年来发表的科学文章,包括临床、准实验、横断面设计和对更年期妇女进行的案例研究。2010年以前发表的有描述的文章被排除在外;流行病学,系统回顾,荟萃分析,动物模型实验研究。综述中包含的研究被完整地阅读、批判性地分析和分类。研究结果表明,积极运动的妇女减少了更年期的血管舒缩和躯体症状,也有助于预防这一时期流行的疾病。有氧体育锻炼可改善更年期妇女的体质和生活质量指标。在临床实践中,有氧运动可视为治疗更年期症状和改善女性健康的辅助策略。关键词:更年期。健康。体育锻炼。ResumoO climaterio e嗯processo自然caracterizado佩拉reducao dos hormonios femininos e aumento de产生,interferem na qualidade de维达da mulher。目的:利用相关的科学证据,探讨运动健身对人体健康的影响。《沙特阿拉伯虚拟图书馆系统访问修订研究报告》(以下简称《研究报告》)和《法律准则汇编》(以下简称《标准汇编》);包括人工科学描述、临床描述、准实验描述、横向研究描述等。前牙骨质疏松症[a], 2010;流行病学,修正系统,元分析,研究实验,动物模型。它的研究包括修正、整合、分析、批评和分类。Os achados demonstraram, mulheres ativas apresentam reducao dos产生血管舒缩性e somaticos climaterio, tambem colabora na prevencao de doencas普遍nesse periodo。(3)运动、运动、有氧运动和适宜的运动指标。目前临床上对运动有氧运动的临床研究主要集中在对运动有氧运动的治疗策略、辅助治疗方法、治疗方法等方面。Palavras-chave: Climaterio。Saude。Exercicio达到。
{"title":"Exercise as a Therapeutic and Supporting Strategy for Climacteric Symptoms: an Evidence-Based Review","authors":"R. Pereira Pinto, D. M. D. Oliveira, Anderson Geremias Macedo, Giselle Soares Passos","doi":"10.17921/2447-8938.2021V23N1P35-38","DOIUrl":"https://doi.org/10.17921/2447-8938.2021V23N1P35-38","url":null,"abstract":"AbstractClimacteric is a natural process characterized by the female hormones reduction and increased symptoms that interfere in the woman's quality of life. The objective was to raise scientific evidence on the physical exercise effects as a therapeutic strategy on climacteric symptoms. This systematic review study accessed the Virtual Health Library (VHL) and consulted articles from the last 10 years, with the following eligibility criteria; inclusion, scientific articles published in the last 10 years, with clinical, quasi-experimental, cross-sectional design and case studies conducted with women in the climacteric. Articles published before 2010 with delineations were excluded; epidemiological, systematic review, meta-analyzes, experimental studies with animal model. The studies included in the review were read in full, critically analyzed and categorized. The findings showed that active women have a reduction in vasomotor and somatic symptoms of the climacteric, also collaborating in the prevention of diseases prevalent in this period. Aerobic physical exercise improves physical fitness and quality of life indicators of climacteric women. In clinical practice, aerobic exercise can be considered an auxiliary strategy in the climacteric symptoms treatment and female health improvement. \u0000Keywords: Climacteric. Health. Physical Exercise. \u0000ResumoO climaterio e um processo natural caracterizado pela reducao dos hormonios femininos e aumento de sintomas que interferem na qualidade de vida da mulher. Objetivou-se levantar evidencias cientificas sobre os efeitos do exercicio fisico como estrategia terapeutica na sintomatologia climaterica. Este estudo de revisao sistematica acessou a Biblioteca Virtual de Saude (BVS) e consultou artigo dos ultimos 10 anos, com os seguintes criterios de elegibilidade; inclusao, artigos cientificos com delineamento clinico, quase-experimental, transversal e estudos de caso realizados com mulheres no climaterio. Foram excluidos artigos publicados anterior a 2010, com delineamentos; epidemiologico, revisao sistematica, metanalises, estudos experimentais com modelo animal. Os estudos incluidos na revisao foram lidos na integra, analisados criticamente e categorizados. Os achados demonstraram que mulheres ativas apresentam reducao dos sintomas vasomotores e somaticos do climaterio, tambem colabora na prevencao de doencas prevalentes nesse periodo. O exercicio fisico aerobio melhora a aptidao fisica e indicadores de qualidade de vida de mulheres climatericas. Na pratica clinica o exercicio aerobio pode ser considerado uma estrategia auxiliar no tratamento dos sintomas do climaterio e melhora da saude feminina. \u0000Palavras-chave: Climaterio. Saude. Exercicio Fisico.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"194 1","pages":"35-38"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90459637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P30-34
M. Cespedes, Tania Gisela Biberg-Salum, Rosilene Canavarros Monteiro
The objective of this study was to determine factors associated with asthma control in patients attending Lam Plai Mat Hospital, Buri Ram Province. The study samples were asthma patients aged over 15 years old who attended the hospital during October 2009 to September 2010. Data were collected through interviews using a set of questionnaire and an asthma assessment tool (asthma control test). Data were analyzed using chi-square test and multiple logistic regression. There were 365 asthma patients participated in the study. It was found that 16 patients (4.38%) were classified as keeping asthma under control; 160 patients (43.84%) whose asthma condition was partially under controlled and 189 patients (51.78%) whose asthma condition was not under control. Factors associated with the ability to control the disease were (1) having family history of asthma (adjusted OR 2.2 95%CI 1.2, 4.0), (2) non-availability of bronchodilator inhaler (adjusted OR 0.3 95% CI 0.1, 0.5), (3) expose to incense smoke (adjusted OR 2.0 95% CI 1.1, 3.6), (4) expose to cold weather (adjusted OR 3.1 95% CI 1.8, 5.3), and (5) expose to smoke from cooking (adjusted OR 2.1 95% CI 1.2, 3.8). Results of this study indicated that asthma patients had capability to control asthma at low level. Thus it was recommended that health personnel at primary care units should conduct more frequent home visit to all asthma patients to monitor self-care practice and control exposure to environmental pollutants. For health care facilities, it was recommended to assess pulmonary function periodically in order to monitor the effectiveness of the treatment and to improve the care of asthma patients. Key words: asthma, factors associated with asthma attacks, level of asthma self-control
{"title":"Prevalence of Dyschromatopsias in the Academic Community of a Medicine School Course","authors":"M. Cespedes, Tania Gisela Biberg-Salum, Rosilene Canavarros Monteiro","doi":"10.17921/2447-8938.2021V23N1P30-34","DOIUrl":"https://doi.org/10.17921/2447-8938.2021V23N1P30-34","url":null,"abstract":"The objective of this study was to determine factors associated with asthma control in patients attending Lam Plai Mat Hospital, Buri Ram Province. The study samples were asthma patients aged over 15 years old who attended the hospital during October 2009 to September 2010. Data were collected through interviews using a set of questionnaire and an asthma assessment tool (asthma control test). Data were analyzed using chi-square test and multiple logistic regression. There were 365 asthma patients participated in the study. It was found that 16 patients (4.38%) were classified as keeping asthma under control; 160 patients (43.84%) whose asthma condition was partially under controlled and 189 patients (51.78%) whose asthma condition was not under control. Factors associated with the ability to control the disease were (1) having family history of asthma (adjusted OR 2.2 95%CI 1.2, 4.0), (2) non-availability of bronchodilator inhaler (adjusted OR 0.3 95% CI 0.1, 0.5), (3) expose to incense smoke (adjusted OR 2.0 95% CI 1.1, 3.6), (4) expose to cold weather (adjusted OR 3.1 95% CI 1.8, 5.3), and (5) expose to smoke from cooking (adjusted OR 2.1 95% CI 1.2, 3.8). Results of this study indicated that asthma patients had capability to control asthma at low level. Thus it was recommended that health personnel at primary care units should conduct more frequent home visit to all asthma patients to monitor self-care practice and control exposure to environmental pollutants. For health care facilities, it was recommended to assess pulmonary function periodically in order to monitor the effectiveness of the treatment and to improve the care of asthma patients. Key words: asthma, factors associated with asthma attacks, level of asthma self-control","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"321 1","pages":"30-36"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74977041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P79-83
Marcelo Yudi Sakamoto, M. Oliveira, N. Macedo, H. O. Schwartz-Filho
AbstractGingival smile is a term used to describe an aesthetic condition in which excessive gingival exposure at the jaw level occurs during smile. There are several factors related to its etiology, the most common is the altered passive eruption of anterior superior teeth. To correct this disharmony, a multidisciplinary approach is necessary, and the treatment plan depends on a correct diagnosis and assessment for a better prognosis. The present study aims to describe a clinical case where periodontal surgical techniques were used to correct this condition. Female patient, 25 years old, with aesthetic complaint of the amount of gum exposed when smiling and diagnosed with altered passive eruption. Clinical crown augmentation surgery was performed on the anterior superior teeth. After 1 and 2 years, periodontal clinical parameters (probing bleeding, probing depth, clinical attachment level, crown length, keratinized mucosa width and plaque index) were reassessed, through clinical examination, digital photographic monitoring and measurement tools. In two years, it was possible to note the stability of the results achieved, maintaining values similar to those of the immediate postoperative period. The case report confirmed the success of the clinical crown augmentation surgery and the periodontal parameters stability evaluated after 2 years. Keywords: Periodontics Surgery. Gingivectomy. Aesthetics. ResumoSorriso gengival e o termo utilizado para descrever uma condicao estetica em que ocorre uma exposicao gengival excessiva ao nivel da maxila, durante o sorriso. Ha diversos fatores relacionados a sua etiologia, sendo a mais comum a erupcao passiva alterada dos dentes ântero-superiores. Para correcao dessa desarmonia e necessaria uma abordagem multidisciplinar, sendo o plano de tratamento dependente de um correto diagnostico e avaliacao para um melhor prognostico. O presente estudo tem objetivo de descrever um caso clinico onde tecnicas cirurgicas periodontais foram utilizadas para correcao dessa condicao. Paciente genero feminino, 25 anos de idade, com queixa estetica da quantidade de gengiva exposta ao sorrir e com diagnostico de erupcao passiva alterada. Foi submetida a cirurgia de aumento de coroa clinica nos dentes antero-superiores. Apos 1 e 2 anos foram reavaliados os parâmetros clinicos periodontais (sangramento a sondagem, profundidade de sondagem, perda de insercao, comprimento da coroa, largura da mucosa queratinizada e indice de placa), atraves de exame clinico, acompanhamento digital fotografico e ferramentas de medicao de imagem. Em dois anos, foi possivel constatar a estabilidade dos resultados alcancados, mantendo valores semelhantes aos do pos-operatorio imediato. O relato de caso confirmou o sucesso da cirurgia de aumento de coroa clinica e a estabilidade dos parâmetros periodontais avaliados apos 2 anos. Palavras-chave: Periodontia. Cirurgia. Gengivectomia. Estetica.
{"title":"Periodontal Surgery for Correction of Gingival Smile: a Case Report Analysis of Periodontal Parameters after 2 Years","authors":"Marcelo Yudi Sakamoto, M. Oliveira, N. Macedo, H. O. Schwartz-Filho","doi":"10.17921/2447-8938.2021V23N1P79-83","DOIUrl":"https://doi.org/10.17921/2447-8938.2021V23N1P79-83","url":null,"abstract":"AbstractGingival smile is a term used to describe an aesthetic condition in which excessive gingival exposure at the jaw level occurs during smile. There are several factors related to its etiology, the most common is the altered passive eruption of anterior superior teeth. To correct this disharmony, a multidisciplinary approach is necessary, and the treatment plan depends on a correct diagnosis and assessment for a better prognosis. The present study aims to describe a clinical case where periodontal surgical techniques were used to correct this condition. Female patient, 25 years old, with aesthetic complaint of the amount of gum exposed when smiling and diagnosed with altered passive eruption. Clinical crown augmentation surgery was performed on the anterior superior teeth. After 1 and 2 years, periodontal clinical parameters (probing bleeding, probing depth, clinical attachment level, crown length, keratinized mucosa width and plaque index) were reassessed, through clinical examination, digital photographic monitoring and measurement tools. In two years, it was possible to note the stability of the results achieved, maintaining values similar to those of the immediate postoperative period. The case report confirmed the success of the clinical crown augmentation surgery and the periodontal parameters stability evaluated after 2 years. \u0000Keywords: Periodontics Surgery. Gingivectomy. Aesthetics. \u0000ResumoSorriso gengival e o termo utilizado para descrever uma condicao estetica em que ocorre uma exposicao gengival excessiva ao nivel da maxila, durante o sorriso. Ha diversos fatores relacionados a sua etiologia, sendo a mais comum a erupcao passiva alterada dos dentes ântero-superiores. Para correcao dessa desarmonia e necessaria uma abordagem multidisciplinar, sendo o plano de tratamento dependente de um correto diagnostico e avaliacao para um melhor prognostico. O presente estudo tem objetivo de descrever um caso clinico onde tecnicas cirurgicas periodontais foram utilizadas para correcao dessa condicao. Paciente genero feminino, 25 anos de idade, com queixa estetica da quantidade de gengiva exposta ao sorrir e com diagnostico de erupcao passiva alterada. Foi submetida a cirurgia de aumento de coroa clinica nos dentes antero-superiores. Apos 1 e 2 anos foram reavaliados os parâmetros clinicos periodontais (sangramento a sondagem, profundidade de sondagem, perda de insercao, comprimento da coroa, largura da mucosa queratinizada e indice de placa), atraves de exame clinico, acompanhamento digital fotografico e ferramentas de medicao de imagem. Em dois anos, foi possivel constatar a estabilidade dos resultados alcancados, mantendo valores semelhantes aos do pos-operatorio imediato. O relato de caso confirmou o sucesso da cirurgia de aumento de coroa clinica e a estabilidade dos parâmetros periodontais avaliados apos 2 anos. \u0000Palavras-chave: Periodontia. Cirurgia. Gengivectomia. Estetica.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"60 1","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88748996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-18DOI: 10.17921/2447-8938.2021V23N1P72-78
A. Grala, Éderson Candellório, P. Sperandio, Emilly Aparecida da Gama Maldonado, Bruno Henrique Beltramel dos Anjos, J. L. Jacinto, Juliano Casonatto, A. Aguiar
AbstractThe aim of this study was to evaluate the effects of citrulline malate (CIT) supplementation on aerobic and muscular endurance in young adult males. Eighteen young adult men (age: 21.5 ± 2.7 years) were randomized into two groups (Citrulline malate - CIT and Placebo - PLA; N = 9/group ) and received the respective supplements for 7 days. The CIT group was supplemented with 6 g CIT + 6 g dextrose (total: 12 g), while the PLA group received the same amount (12 g) of dextrose. At the pre- and post-supplementation, the following variables were analyzed: aerobic (maximal treadmill test, Tmax) and muscle (repetitions maximum test, Rmax) endurance tests, as well as mean and maximum heart rate (HR) in Tmax and ratings of perceived exertion (PSE) in Rmax. No significant (P > 0.05) differences were found between CIT and PLA groups in time until exhaustion in Tmax, total repetitions in Rmax, maximal HR and PSE from pre- to post-supplementation. The mean HR was statistically lower (P < 0.05) in the CIT group compared to the PLA in the Tmax. In conclusion, supplementation of CIT (6 g / day) does not improve aerobic and muscular endurance, as well as maximal HR or PSE in healthy young adults, despite reducing the mean HR during the maximal incremental test. Keywords: Endurance Training. Dietary Supplements. Physical Functional Performance. Citrulline. Nitric Oxide. ResumoO objetivo deste estudo foi avaliar os efeitos da suplementacao de citrulina malato (CIT) sobre a resistencia aerobica e muscular em homens adultos jovens. Em um desenho experimental randomizado, duplo-cego e controlado com placebo, dezoito homens adultos jovens (idade: 21,5 ± 2,7 anos) foram randomizados em dois grupos (Citrulina malato – CIT e Placebo – PLA; N = 9/grupo) e receberam os respectivos suplementos por um periodo de 7 dias. O grupo CIT foi suplementado com 6 g de CIT + 6 g de dextrose (total: 12 g), enquanto o grupo PLA recebeu a mesma quantidade (12 g) de dextrose. Nos momentos pre e pos suplementacao as seguintes variaveis foram analisadas: resistencia aerobia (teste incremental maximo em esteira rolante, Tmax) e muscular (teste de repeticoes maximas, Rmax), bem como a frequencia cardiaca (FC) media e maxima no Tmax e a analise da percepcao subjetiva de esforco (PSE) no Rmax. Nenhuma diferenca significante (P > 0,05) foi encontrada entre os grupos CIT e PLA no tempo ate a exaustao no Tmax, total de repeticoes no Rmax, FC maxima e PSE do momento pre para o pos suplementacao. A FC media foi estatisticamente (P < 0,05) menor no grupo CIT comparado ao PLA no Tmax. Em conclusao, a suplementacao de CIT (6 g/dia) nao melhora a resistencia aerobica e muscular, bem como a FC maxima ou PSE em adultos jovens saudaveis, apesar de reduzir a FC media durante o teste incremental maximo. Palavras-chave: Treino Aerobico. Suplementos Nutricionais. Desempenho Fisico Funcional. Citrulina. Oxido Nitrico.
{"title":"Effects of Citrulline Malate Supplementation on Aerobic and Muscular Endurance in Young Adults Men","authors":"A. Grala, Éderson Candellório, P. Sperandio, Emilly Aparecida da Gama Maldonado, Bruno Henrique Beltramel dos Anjos, J. L. Jacinto, Juliano Casonatto, A. Aguiar","doi":"10.17921/2447-8938.2021V23N1P72-78","DOIUrl":"https://doi.org/10.17921/2447-8938.2021V23N1P72-78","url":null,"abstract":"AbstractThe aim of this study was to evaluate the effects of citrulline malate (CIT) supplementation on aerobic and muscular endurance in young adult males. Eighteen young adult men (age: 21.5 ± 2.7 years) were randomized into two groups (Citrulline malate - CIT and Placebo - PLA; N = 9/group ) and received the respective supplements for 7 days. The CIT group was supplemented with 6 g CIT + 6 g dextrose (total: 12 g), while the PLA group received the same amount (12 g) of dextrose. At the pre- and post-supplementation, the following variables were analyzed: aerobic (maximal treadmill test, Tmax) and muscle (repetitions maximum test, Rmax) endurance tests, as well as mean and maximum heart rate (HR) in Tmax and ratings of perceived exertion (PSE) in Rmax. No significant (P > 0.05) differences were found between CIT and PLA groups in time until exhaustion in Tmax, total repetitions in Rmax, maximal HR and PSE from pre- to post-supplementation. The mean HR was statistically lower (P < 0.05) in the CIT group compared to the PLA in the Tmax. In conclusion, supplementation of CIT (6 g / day) does not improve aerobic and muscular endurance, as well as maximal HR or PSE in healthy young adults, despite reducing the mean HR during the maximal incremental test. \u0000Keywords: Endurance Training. Dietary Supplements. Physical Functional Performance. Citrulline. Nitric Oxide. \u0000ResumoO objetivo deste estudo foi avaliar os efeitos da suplementacao de citrulina malato (CIT) sobre a resistencia aerobica e muscular em homens adultos jovens. Em um desenho experimental randomizado, duplo-cego e controlado com placebo, dezoito homens adultos jovens (idade: 21,5 ± 2,7 anos) foram randomizados em dois grupos (Citrulina malato – CIT e Placebo – PLA; N = 9/grupo) e receberam os respectivos suplementos por um periodo de 7 dias. O grupo CIT foi suplementado com 6 g de CIT + 6 g de dextrose (total: 12 g), enquanto o grupo PLA recebeu a mesma quantidade (12 g) de dextrose. Nos momentos pre e pos suplementacao as seguintes variaveis foram analisadas: resistencia aerobia (teste incremental maximo em esteira rolante, Tmax) e muscular (teste de repeticoes maximas, Rmax), bem como a frequencia cardiaca (FC) media e maxima no Tmax e a analise da percepcao subjetiva de esforco (PSE) no Rmax. Nenhuma diferenca significante (P > 0,05) foi encontrada entre os grupos CIT e PLA no tempo ate a exaustao no Tmax, total de repeticoes no Rmax, FC maxima e PSE do momento pre para o pos suplementacao. A FC media foi estatisticamente (P < 0,05) menor no grupo CIT comparado ao PLA no Tmax. Em conclusao, a suplementacao de CIT (6 g/dia) nao melhora a resistencia aerobica e muscular, bem como a FC maxima ou PSE em adultos jovens saudaveis, apesar de reduzir a FC media durante o teste incremental maximo. \u0000Palavras-chave: Treino Aerobico. Suplementos Nutricionais. Desempenho Fisico Funcional. Citrulina. Oxido Nitrico.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"50 1","pages":"72-78"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81787917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}