首页 > 最新文献

Journal of hospital medicine最新文献

英文 中文
Point-counterpoint: Should chronic disease medications be adjusted during unrelated hospitalizations? 观点/反题:在不相关的住院期间,慢性病药物是否应该调整?
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-31 DOI: 10.1002/jhm.70143
Zachary G. Jacobs MD, FHM, FACP, Michael Rothberg MD, MPH, Thomas E. MacMillan MD, MSc

Patients in the hospital frequently have multiple chronic conditions in addition to their acute illnesses. Inpatient providers may feel pressured to adjust outpatient medication regimens in response to acute variations in labs or vital signs during hospitalization, or in an attempt to optimize long-term disease control. However, this practice should generally be deferred to the outpatient setting, as the effective management of chronic conditions requires longitudinal care and should take place during periods of homeostasis. In select circumstances and for certain high-risk patients, stepwise modifications to chronic disease medications may be considered during hospitalization, but this should always be coordinated with the primary care provider.

医院里的病人除了急性病外,还经常患有多种慢性疾病。住院病人提供者可能会感到压力,调整门诊用药方案,以应对住院期间实验室或生命体征的急性变化,或试图优化长期疾病控制。然而,这种做法通常应该推迟到门诊设置,因为慢性病的有效管理需要纵向护理,应该在体内平衡期间进行。在特定情况下和某些高危患者,住院期间可考虑逐步调整慢性病药物,但这应始终与初级保健提供者协调。
{"title":"Point-counterpoint: Should chronic disease medications be adjusted during unrelated hospitalizations?","authors":"Zachary G. Jacobs MD, FHM, FACP,&nbsp;Michael Rothberg MD, MPH,&nbsp;Thomas E. MacMillan MD, MSc","doi":"10.1002/jhm.70143","DOIUrl":"10.1002/jhm.70143","url":null,"abstract":"<p>Patients in the hospital frequently have multiple chronic conditions in addition to their acute illnesses. Inpatient providers may feel pressured to adjust outpatient medication regimens in response to acute variations in labs or vital signs during hospitalization, or in an attempt to optimize long-term disease control. However, this practice should generally be deferred to the outpatient setting, as the effective management of chronic conditions requires longitudinal care and should take place during periods of homeostasis. In select circumstances and for certain high-risk patients, stepwise modifications to chronic disease medications may be considered during hospitalization, but this should always be coordinated with the primary care provider.</p>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"20 11","pages":"1240-1244"},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overlap between transitional care management after hospital discharge and alternative payment models 出院后过渡性护理管理与替代支付模式之间的重叠。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-21 DOI: 10.1002/jhm.70085
Joseph H. Joo MD, MS, MacKenzie L. Hughes PhD, Wen Hu MS, Jackie Soo ScD, Shriram Parashuram PhD, MPH, Adil Moiduddin MPP, Steven Sheingold PhD, Joshua M. Liao MD, MSc

Care coordination is integral during posthospital transitions. The Centers for Medicare & Medicaid Services (CMS) has sought to promote post-hospitalization care coordination through population-based alternative payment models (APMs) and transitional care management (TCM) services. Both can be associated with benefits, but data are lacking about their overlap. Using 2018–2019 100% Medicare claims, we compared characteristics and quantified overlap across APM and TCM groups. Of 7,034,244 beneficiaries and 11,148,266 discharges, 41.6% were APM-aligned and 14.5% involved TCM. TCM services were received in 19.7% of APM-aligned discharges; among discharges involving TCM, 56.7% occurred among APM-aligned beneficiaries. Relative to non-APM beneficiaries, APM-aligned beneficiaries receiving TCM were less likely to be from historically underserved populations, suggesting potential health disparity concerns. This early descriptive analysis offers novel evidence about TCM and APMs as major national policy investments, highlighting the need for future work on overlap and its effects on care coordination and patient outcomes.

在医院转院期间,护理协调是不可或缺的。医疗保险和医疗补助服务中心(CMS)通过基于人群的替代支付模式(APMs)和过渡性护理管理(TCM)服务,寻求促进住院后护理协调。两者都与利益有关,但缺乏关于它们重叠的数据。使用2018-2019年100%医疗保险索赔,我们比较了APM组和TCM组的特征和量化重叠。在7034244名受益人和11148266名出院患者中,41.6%采用apm, 14.5%采用中医。19.7%的患者接受了中医服务;在涉及中医的出院中,56.7%发生在符合apm的受益人中。与非apm受益人相比,接受中医治疗的apm受益人不太可能来自历史上服务不足的人群,这表明存在潜在的健康差异问题。这一早期描述性分析提供了新的证据,证明中医和apm是主要的国家政策投资,强调了未来需要开展重叠工作及其对护理协调和患者预后的影响。
{"title":"Overlap between transitional care management after hospital discharge and alternative payment models","authors":"Joseph H. Joo MD, MS,&nbsp;MacKenzie L. Hughes PhD,&nbsp;Wen Hu MS,&nbsp;Jackie Soo ScD,&nbsp;Shriram Parashuram PhD, MPH,&nbsp;Adil Moiduddin MPP,&nbsp;Steven Sheingold PhD,&nbsp;Joshua M. Liao MD, MSc","doi":"10.1002/jhm.70085","DOIUrl":"10.1002/jhm.70085","url":null,"abstract":"<p>Care coordination is integral during posthospital transitions. The Centers for Medicare &amp; Medicaid Services (CMS) has sought to promote post-hospitalization care coordination through population-based alternative payment models (APMs) and transitional care management (TCM) services. Both can be associated with benefits, but data are lacking about their overlap. Using 2018–2019 100% Medicare claims, we compared characteristics and quantified overlap across APM and TCM groups. Of 7,034,244 beneficiaries and 11,148,266 discharges, 41.6% were APM-aligned and 14.5% involved TCM. TCM services were received in 19.7% of APM-aligned discharges; among discharges involving TCM, 56.7% occurred among APM-aligned beneficiaries. Relative to non-APM beneficiaries, APM-aligned beneficiaries receiving TCM were less likely to be from historically underserved populations, suggesting potential health disparity concerns. This early descriptive analysis offers novel evidence about TCM and APMs as major national policy investments, highlighting the need for future work on overlap and its effects on care coordination and patient outcomes.</p>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"21 1","pages":"59-63"},"PeriodicalIF":2.3,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increased lumbar puncture success using a paramedian approach: A retrospective cohort study 使用辅助方法增加腰椎穿刺成功率:一项回顾性队列研究。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-21 DOI: 10.1002/jhm.70138
Jacob Wagner MD, Kiril Dimitrov MD, Zachary Lauer MD, Swati Jain MBBS, Omar Jibril MD, Zach Kaltenborn MD, Aditya Kler MD, Andrew Olson MD, Justin Clark PhD, Kyle Rudser PhD, Matthew Yocum MD

Background

Lumbar puncture (LP) is frequently necessary in hospitalized patients for diagnostic and therapeutic purposes. Traditional landmark identification by palpation of the lumbar spine and pelvis can see significant failure rates. A paramedian approach is an accepted, though less frequently used technique associated with higher success rates for spinal access in anesthesia when aided by ultrasound. Similarly, point-of-care ultrasound (POCUS) of the paramedian acoustic window may help guide a paramedian LP technique.

Objective

To compare the probability of success before and after the implementation of a standardized training curriculum for lumbar punctures (LPs) performed by the Hospital Medicine Procedure Service (HMPS).

Methods

The HMPS at the University of Minnesota Medical Center (UMMC), a large tertiary academic medical center, implemented a standardized training for an ultrasound-assisted paramedian (USPM) approach to all bedside lumbar punctures (LPs) and then conducted a retrospective review comparing success rates between the traditional midline (ML) and USPM approaches.

Results

A total of 269 LPs were performed on hospitalized patients. Before standardization, the probability of a successful LP was 72.6% using ML approach. After standardization, using a USPM approach, the probability of a successful LP was 85.4%. The probability of a successful procedure was 13.6 (95% confidence interval: 2.8, 24.4, p = .014) percentage points higher for the USPM approach when compared to the ML approach and accounting for sex, age, BMI, and if the LP was for chemotherapy.

Conclusions

Institutions with a HMPS should consider transitioning to use of the USPM approach for bedside LPs, which is associated with a higher probability of success and reduced utilization of more resource-intensive hospital services, such as Interventional Radiology or Neuroradiology.

背景:腰椎穿刺(LP)是住院患者诊断和治疗的必要手段。通过触诊腰椎和骨盆的传统地标识别可以看到显着的失败率。辅助入路是一种被接受的方法,尽管使用频率较低,但在超声辅助下麻醉脊柱入路的成功率较高。类似地,护理点超声(POCUS)的声窗可能有助于指导护理点LP技术。目的:比较医院医学程序服务(HMPS)实施腰椎穿刺(lp)标准化培训课程前后的成功率。方法:明尼苏达大学医学中心(UMMC)的HMPS是一家大型三级学术医疗中心,对超声辅助辅助人员(USPM)入路对所有床边腰椎穿刺术(LPs)实施了标准化培训,然后对传统中线(ML)和USPM入路的成功率进行了回顾性比较。结果:共对住院患者进行了269次LPs手术。在标准化之前,使用ML方法成功LP的概率为72.6%。标准化后,使用USPM方法,LP成功的概率为85.4%。与ML入路相比,考虑到性别、年龄、BMI和LP是否用于化疗等因素,USPM入路手术成功的概率为13.6个百分点(95%可信区间:2.8,24.4,p = 0.014)。结论:拥有HMPS的机构应考虑过渡到使用USPM方法治疗床边lp,这与更高的成功率相关,并减少对更多资源密集型医院服务的利用,如介入放射学或神经放射学。
{"title":"Increased lumbar puncture success using a paramedian approach: A retrospective cohort study","authors":"Jacob Wagner MD,&nbsp;Kiril Dimitrov MD,&nbsp;Zachary Lauer MD,&nbsp;Swati Jain MBBS,&nbsp;Omar Jibril MD,&nbsp;Zach Kaltenborn MD,&nbsp;Aditya Kler MD,&nbsp;Andrew Olson MD,&nbsp;Justin Clark PhD,&nbsp;Kyle Rudser PhD,&nbsp;Matthew Yocum MD","doi":"10.1002/jhm.70138","DOIUrl":"10.1002/jhm.70138","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Lumbar puncture (LP) is frequently necessary in hospitalized patients for diagnostic and therapeutic purposes. Traditional landmark identification by palpation of the lumbar spine and pelvis can see significant failure rates. A paramedian approach is an accepted, though less frequently used technique associated with higher success rates for spinal access in anesthesia when aided by ultrasound. Similarly, point-of-care ultrasound (POCUS) of the paramedian acoustic window may help guide a paramedian LP technique.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To compare the probability of success before and after the implementation of a standardized training curriculum for lumbar punctures (LPs) performed by the Hospital Medicine Procedure Service (HMPS).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The HMPS at the University of Minnesota Medical Center (UMMC), a large tertiary academic medical center, implemented a standardized training for an ultrasound-assisted paramedian (USPM) approach to all bedside lumbar punctures (LPs) and then conducted a retrospective review comparing success rates between the traditional midline (ML) and USPM approaches.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 269 LPs were performed on hospitalized patients. Before standardization, the probability of a successful LP was 72.6% using ML approach. After standardization, using a USPM approach, the probability of a successful LP was 85.4%. The probability of a successful procedure was 13.6 (95% confidence interval: 2.8, 24.4, <i>p</i> = .014) percentage points higher for the USPM approach when compared to the ML approach and accounting for sex, age, BMI, and if the LP was for chemotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Institutions with a HMPS should consider transitioning to use of the USPM approach for bedside LPs, which is associated with a higher probability of success and reduced utilization of more resource-intensive hospital services, such as Interventional Radiology or Neuroradiology.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"21 1","pages":"42-48"},"PeriodicalIF":2.3,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of a best practice advisory for shifting to oral medications: A quality improvement project 转向口服药物的最佳实践建议的影响:质量改进项目。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-18 DOI: 10.1002/jhm.70127
Rebecca Y. Linfield MD, MS, Leon S. Moskatel MD, Sean Carlton PharmD, BCPS, Fatemeh Amrollahi PhD, David Epstein MD, Amy Chang MD, PharmD, David Svec MD, MBA, Jonathan H. Chen MD, PhD, Lisa Shieh MD, PhD

We developed a Best Practice Advisory (BPA) to encourage switching from intravenous (IV) to oral (PO) formulations of antimicrobials with equal efficacy, to decrease costs and IV usage. We conducted a prospective study analyzing our BPA's effect on prescribing practices of antimicrobials in the inpatient setting of Stanford Hospital in Palo Alto, CA, over a 22-month period. Our BPA achieved a 1526/6585 (23.2%) acceptance rate and led to decreased use of IV antimicrobials, with substantial direct cost savings of at least $66,976. Future efforts will focus on expanding our BPA to non-antimicrobials given ongoing IV fluid shortages.

我们制定了最佳实践建议(BPA),以鼓励从静脉注射(IV)改为口服(PO)配方的抗菌素具有相同的疗效,以降低成本和静脉注射的使用。我们进行了一项前瞻性研究,分析BPA对加州帕洛阿尔托斯坦福医院住院患者抗菌剂处方的影响,为期22个月。我们的BPA达到了1526/6585(23.2%)的接受率,并减少了静脉注射抗菌剂的使用,节省了至少66,976美元的直接成本。鉴于持续的静脉输液短缺,未来的努力将集中于将我们的双酚a扩展到非抗菌剂。
{"title":"The impact of a best practice advisory for shifting to oral medications: A quality improvement project","authors":"Rebecca Y. Linfield MD, MS,&nbsp;Leon S. Moskatel MD,&nbsp;Sean Carlton PharmD, BCPS,&nbsp;Fatemeh Amrollahi PhD,&nbsp;David Epstein MD,&nbsp;Amy Chang MD, PharmD,&nbsp;David Svec MD, MBA,&nbsp;Jonathan H. Chen MD, PhD,&nbsp;Lisa Shieh MD, PhD","doi":"10.1002/jhm.70127","DOIUrl":"10.1002/jhm.70127","url":null,"abstract":"<p>We developed a Best Practice Advisory (BPA) to encourage switching from intravenous (IV) to oral (PO) formulations of antimicrobials with equal efficacy, to decrease costs and IV usage. We conducted a prospective study analyzing our BPA's effect on prescribing practices of antimicrobials in the inpatient setting of Stanford Hospital in Palo Alto, CA, over a 22-month period. Our BPA achieved a 1526/6585 (23.2%) acceptance rate and led to decreased use of IV antimicrobials, with substantial direct cost savings of at least $66,976. Future efforts will focus on expanding our BPA to non-antimicrobials given ongoing IV fluid shortages.</p>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"20 12","pages":"1377-1382"},"PeriodicalIF":2.3,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supportive noninvasive ventilation for acute chest syndrome prevention in hospitalized children with sickle cell disease: Determinants of implementation 支持无创通气预防住院儿童镰状细胞病急性胸综合征:实施的决定因素
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-17 DOI: 10.1002/jhm.70137
Shana A. Burrowes PhD, Kayla C. Jones MA, Christopher J. Williams MS, Caitlin M. Neri MD, MPH, Elizabeth S. Klings MD, Scarlett L. Bellamy ScD, Allan J. Walkey MD, MSc, Mari-Lynn Drainoni PhD, MEd, Robyn T. Cohen MD, MPH

Background

In 2017 Boston Medical Center's (BMC) general pediatric inpatient unit implemented bi-level positive airway pressure (BiPAP) as supportive noninvasive ventilation for acute chest syndrome prevention (SNAP) to prevent adverse respiratory outcomes among medically stable, hospitalized patients with sickle cell disease. Barriers and facilitators to SNAP implementation at BMC differ from those in other settings.

Objective

To examine contextual determinants of SNAP implementation across different settings.

Methods

We conducted semi-structured interviews with inpatient clinicians at three sites (Site 1: extensive implementation, Site 2: limited implementation, Site 3: not implemented) about factors that would affect SNAP implementation. Interviews and analysis were guided by the Promoting Action on Research Implementation in Health Services (PARiHS) framework.

Results

We interviewed 29 healthcare workers (physicians, nurses, physician assistants, child life specialists, respiratory therapists and psychologists). Five major themes emerged: (1) Communication between staff, particularly between the night and day shift, is critical for BiPAP initiation and success. (2) Nurses are key to successful SNAP implementation. (3) SNAP implementation requires multidisciplinary support, including integration of respiratory therapists and child life. (4) Individual unit level size, culture and workflow influence implementation (5) Hospital resources and leadership support are important for SNAP implementation.

Conclusions

Successful SNAP implementation across different contexts will require optimized communication between healthcare team members and the integration of respiratory therapy and child life early in the process of BiPAP initiation. Adapting to the unique features of each institution will be critical.

背景:2017年,波士顿医疗中心(BMC)普通儿科住院病房实施双水平气道正压通气(BiPAP)作为急性胸综合征预防(SNAP)的支持性无创通气,以预防医学稳定的住院镰状细胞病患者的不良呼吸结局。在BMC实施SNAP的障碍和促进因素与其他环境不同。目的:研究不同环境下SNAP实施的环境决定因素。方法:我们对三个地点(地点1:广泛实施,地点2:有限实施,地点3:未实施)的住院临床医生进行了半结构化访谈,了解影响SNAP实施的因素。访谈和分析以促进卫生服务研究实施行动框架为指导。结果:我们采访了29名医护人员(医生、护士、医师助理、儿童生活专家、呼吸治疗师和心理学家)。出现了五个主要主题:(1)工作人员之间的沟通,特别是夜班和白班之间的沟通,对于BiPAP的启动和成功至关重要。(2)护士是SNAP成功实施的关键。(3) SNAP的实施需要多学科的支持,包括呼吸治疗师和儿童生活的整合。(4)个体单位规模、文化和工作流程影响SNAP的实施。(5)医院资源和领导支持对SNAP的实施很重要。结论:在不同情况下成功实施SNAP将需要优化医疗团队成员之间的沟通,并在BiPAP启动过程的早期整合呼吸治疗和儿童生活。适应每个机构的独特特点将是至关重要的。
{"title":"Supportive noninvasive ventilation for acute chest syndrome prevention in hospitalized children with sickle cell disease: Determinants of implementation","authors":"Shana A. Burrowes PhD,&nbsp;Kayla C. Jones MA,&nbsp;Christopher J. Williams MS,&nbsp;Caitlin M. Neri MD, MPH,&nbsp;Elizabeth S. Klings MD,&nbsp;Scarlett L. Bellamy ScD,&nbsp;Allan J. Walkey MD, MSc,&nbsp;Mari-Lynn Drainoni PhD, MEd,&nbsp;Robyn T. Cohen MD, MPH","doi":"10.1002/jhm.70137","DOIUrl":"10.1002/jhm.70137","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>In 2017 Boston Medical Center's (BMC) general pediatric inpatient unit implemented bi-level positive airway pressure (BiPAP) as supportive noninvasive ventilation for acute chest syndrome prevention (SNAP) to prevent adverse respiratory outcomes among medically stable, hospitalized patients with sickle cell disease. Barriers and facilitators to SNAP implementation at BMC differ from those in other settings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To examine contextual determinants of SNAP implementation across different settings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted semi-structured interviews with inpatient clinicians at three sites (Site 1: extensive implementation, Site 2: limited implementation, Site 3: not implemented) about factors that would affect SNAP implementation. Interviews and analysis were guided by the Promoting Action on Research Implementation in Health Services (PARiHS) framework.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We interviewed 29 healthcare workers (physicians, nurses, physician assistants, child life specialists, respiratory therapists and psychologists). Five major themes emerged: (1) Communication between staff, particularly between the night and day shift, is critical for BiPAP initiation and success. (2) Nurses are key to successful SNAP implementation. (3) SNAP implementation requires multidisciplinary support, including integration of respiratory therapists and child life. (4) Individual unit level size, culture and workflow influence implementation (5) Hospital resources and leadership support are important for SNAP implementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Successful SNAP implementation across different contexts will require optimized communication between healthcare team members and the integration of respiratory therapy and child life early in the process of BiPAP initiation. Adapting to the unique features of each institution will be critical.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"21 2","pages":"152-163"},"PeriodicalIF":2.3,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustainability of bundled approaches to alarm fatigue: Lessons from a long-term quality improvement study 警报疲劳的捆绑方法的可持续性:来自长期质量改进研究的经验教训。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-17 DOI: 10.1002/jhm.70129
Shogo Akahoshi MD, Shun Nagasawa MD, Kentaro Fukuda MD, Kazuki Iio MD, Nanako Kawata MD, Hidehiro Minegishi MD, Mana Sakatani MD, Akiko Kinumaki MD, Masako Tomotsune BSN, Yoshihiko Morikawa MD, Hiroshi Hataya MD

Background

Physiological monitor alarms are critical for detecting abnormalities but often cause alarm fatigue due to excessive, nonactionable events. This issue is pronounced in the pediatric setting, where movements and crying increase the alarm frequency. The long-term feasibility of countermeasures to reduce alarm fatigue remains underexplored.

Objectives

To evaluate the long-term outcomes of alarm countermeasures implemented through a quality improvement initiative.

Methods

From January 2016 to February 2024, two intervention phases were implemented in nine wards of a tertiary pediatric center, with each phase being followed by a nonintervention period. The first intervention involved monthly data assessment, daily electrode replacement, and discussions about monitoring discontinuation criteria. The second intervention introduced patient-specific alarm thresholds and reminders to reconsider monitoring settings. Alarms were categorized as Advisory, Warning or Crisis. The primary outcome was daily alarm frequency per patient (ppd). A negative binomial regression was used for interrupted time series analysis.

Results

Overall, 46,302,740 alarms in 65,720 patients were analyzed. The alarm frequency declined from approximately 143 ppd to 99 ppd during the first intervention phase but rose to 124 ppd in the subsequent nonintervention phase. In the second intervention phase, the frequency declined to 86 ppd, the lowest value recorded, but rebounded to 165 ppd, the highest level, during the nonintervention phase. Advisory and Warning alarms showed a similar trend while Crisis alarms decreased consistently in the last phase.

Conclusions

The interventions were associated with reduction in the alarm frequency but were unsustainable. Long-term success requires integrating countermeasures into a durable framework.

背景:生理监测报警是检测异常的关键,但往往造成报警疲劳,由于过多的,不可操作的事件。这个问题在儿科环境中很明显,在那里运动和哭泣会增加警报频率。减少报警疲劳的对策的长期可行性仍未得到充分探讨。目的:评价通过质量改进措施实施的报警对策的长期效果。方法:2016年1月至2024年2月,在某三级儿科中心9个病区实施两个阶段的干预,每个阶段后进行一段不干预期。第一次干预包括每月数据评估、每日电极更换和关于监测终止标准的讨论。第二种干预措施引入了针对患者的报警阈值和提醒,以重新考虑监测设置。警报分为警告、警告和危机三类。主要终点是每个患者的每日报警频率(ppd)。中断时间序列分析采用负二项回归。结果:总体而言,分析了65,720例患者的46,302,740例报警。在第一个修井阶段,警报频率从大约143ppd下降到99ppd,但在随后的非修井阶段,警报频率上升到124ppd。在第二个干预阶段,频率下降到86 ppd,为记录的最低值,但在非干预阶段反弹到165 ppd,为最高水平。咨询和警告警报显示出类似的趋势,而危机警报在最后阶段持续下降。结论:干预措施与报警频率的降低有关,但不可持续。长期成功需要将对策纳入持久的框架。
{"title":"Sustainability of bundled approaches to alarm fatigue: Lessons from a long-term quality improvement study","authors":"Shogo Akahoshi MD,&nbsp;Shun Nagasawa MD,&nbsp;Kentaro Fukuda MD,&nbsp;Kazuki Iio MD,&nbsp;Nanako Kawata MD,&nbsp;Hidehiro Minegishi MD,&nbsp;Mana Sakatani MD,&nbsp;Akiko Kinumaki MD,&nbsp;Masako Tomotsune BSN,&nbsp;Yoshihiko Morikawa MD,&nbsp;Hiroshi Hataya MD","doi":"10.1002/jhm.70129","DOIUrl":"10.1002/jhm.70129","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Physiological monitor alarms are critical for detecting abnormalities but often cause alarm fatigue due to excessive, nonactionable events. This issue is pronounced in the pediatric setting, where movements and crying increase the alarm frequency. The long-term feasibility of countermeasures to reduce alarm fatigue remains underexplored.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the long-term outcomes of alarm countermeasures implemented through a quality improvement initiative.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>From January 2016 to February 2024, two intervention phases were implemented in nine wards of a tertiary pediatric center, with each phase being followed by a nonintervention period. The first intervention involved monthly data assessment, daily electrode replacement, and discussions about monitoring discontinuation criteria. The second intervention introduced patient-specific alarm thresholds and reminders to reconsider monitoring settings. Alarms were categorized as Advisory, Warning or Crisis. The primary outcome was daily alarm frequency per patient (ppd). A negative binomial regression was used for interrupted time series analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 46,302,740 alarms in 65,720 patients were analyzed. The alarm frequency declined from approximately 143 ppd to 99 ppd during the first intervention phase but rose to 124 ppd in the subsequent nonintervention phase. In the second intervention phase, the frequency declined to 86 ppd, the lowest value recorded, but rebounded to 165 ppd, the highest level, during the nonintervention phase. Advisory and Warning alarms showed a similar trend while Crisis alarms decreased consistently in the last phase.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The interventions were associated with reduction in the alarm frequency but were unsustainable. Long-term success requires integrating countermeasures into a durable framework.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"21 1","pages":"34-41"},"PeriodicalIF":2.3,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meningitis mirage 脑膜炎海市蜃楼。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-16 DOI: 10.1002/jhm.70134
Ren Kawamura MD, PhD, Takafumi Suzuki MD, Hadzki Matsuda MD, PhD, Kazuyuki Ishida MD, PhD, Andrew A. White MD, Taro Shimizu MD, PhD, MSc, MPH, MBA
{"title":"Meningitis mirage","authors":"Ren Kawamura MD, PhD,&nbsp;Takafumi Suzuki MD,&nbsp;Hadzki Matsuda MD, PhD,&nbsp;Kazuyuki Ishida MD, PhD,&nbsp;Andrew A. White MD,&nbsp;Taro Shimizu MD, PhD, MSc, MPH, MBA","doi":"10.1002/jhm.70134","DOIUrl":"10.1002/jhm.70134","url":null,"abstract":"","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"20 10","pages":"1112-1117"},"PeriodicalIF":2.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Academic internal medicine hospitalist professional identity development 学术内科医院医师职业认同的发展。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-16 DOI: 10.1002/jhm.70132
Valerie J. Lang MD, MHPE, Kimberly Fluet PhD, Kimberly Bloom-Feshbach MD, Maria Klimenko MD

Background

Academic hospitalists have major roles in medical education, clinical care, and other academic medical center missions. Their professional identity development has implications for vitality, burnout, retention, and patient safety.

Objective

To characterize academic internal medicine hospitalist professional identity and its development.

Methods

Ten focus group interviews were conducted with 31 hospitalists in early-, mid-, and late-career stages at three academic medical centers. Data were analyzed using thematic analysis.

Results

Academic hospitalist identity development was characterized by (1) constant core clinician identity, (2) navigating interfaces between different spheres of knowledge, influence, and activity (patients, systems, learners, and multiple medical and psychosocial issues), (3) expanding identities in the “extension zone” outside of patient care, (4) variable and ambiguous academic identity, (5) ongoing negotiation between extrinsic factors (resources, relationships, and validation), intrinsic factors (personal identities and professional values), and identity development, (6) diverse career trajectories, and (7) professional identity driving career decision-making.

Conclusions

In contrast to a “deficit” view of generalists lacking focus on a specific disease or organ system, academic internal medicine hospitalist professional identity encompasses distinct roles and skills. While hospitalists individualize their activities outside the context of patient care, the core clinician identity remains a beacon guiding these activities. Hospitalists’ varied and ambiguous concepts of what it means to be academic may contribute to lagging academic progress. Organizations should support hospitalists’ unique professional identities, seek clarity around what it means to be academic, and foster ongoing professional identity development.

背景:学术医院医师在医学教育、临床护理和其他学术医疗中心任务中发挥着重要作用。他们的职业认同发展对活力、倦怠、留任和患者安全都有影响。目的:探讨专科内科医院医师职业认同及其发展特征。方法:采用10个焦点小组访谈,对3个学术医学中心31名职业生涯早期、中期和晚期的住院医师进行访谈。数据采用专题分析进行分析。结果:学术型医院医生身份发展的特征是:(1)核心临床医生身份不变;(2)在不同的知识、影响和活动领域(患者、系统、学习者和多种医疗和社会心理问题)之间导航界面;(3)在患者护理之外的“扩展区”扩展身份;(4)可变和模糊的学术身份;(5)在外在因素(资源、关系和验证)之间不断协商。内在因素(个人认同与职业价值观)与认同发展;(6)职业轨迹多元化;(7)职业认同驱动职业决策。结论:与多面手缺乏对特定疾病或器官系统的关注的“缺陷”观点相反,学术内科医院医生的职业身份包含了不同的角色和技能。虽然医院医生在病人护理之外个性化他们的活动,但核心临床医生身份仍然是指导这些活动的灯塔。医院医生对学术意义的不同和模糊的概念可能导致学术进步滞后。组织应该支持医院医生独特的职业身份,寻求明确的学术意义,并促进持续的职业身份发展。
{"title":"Academic internal medicine hospitalist professional identity development","authors":"Valerie J. Lang MD, MHPE,&nbsp;Kimberly Fluet PhD,&nbsp;Kimberly Bloom-Feshbach MD,&nbsp;Maria Klimenko MD","doi":"10.1002/jhm.70132","DOIUrl":"10.1002/jhm.70132","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Academic hospitalists have major roles in medical education, clinical care, and other academic medical center missions. Their professional identity development has implications for vitality, burnout, retention, and patient safety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To characterize academic internal medicine hospitalist professional identity and its development.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ten focus group interviews were conducted with 31 hospitalists in early-, mid-, and late-career stages at three academic medical centers. Data were analyzed using thematic analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Academic hospitalist identity development was characterized by (1) constant core clinician identity, (2) navigating interfaces between different spheres of knowledge, influence, and activity (patients, systems, learners, and multiple medical and psychosocial issues), (3) expanding identities in the “extension zone” outside of patient care, (4) variable and ambiguous academic identity, (5) ongoing negotiation between extrinsic factors (resources, relationships, and validation), intrinsic factors (personal identities and professional values), and identity development, (6) diverse career trajectories, and (7) professional identity driving career decision-making.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In contrast to a “deficit” view of generalists lacking focus on a specific disease or organ system, academic internal medicine hospitalist professional identity encompasses distinct roles and skills. While hospitalists individualize their activities outside the context of patient care, the core clinician identity remains a beacon guiding these activities. Hospitalists’ varied and ambiguous concepts of what it means to be academic may contribute to lagging academic progress. Organizations should support hospitalists’ unique professional identities, seek clarity around what it means to be academic, and foster ongoing professional identity development.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"21 2","pages":"125-132"},"PeriodicalIF":2.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variation in effectiveness of blood transfusion by hospital day: A multicenter retrospective study 医院日输血有效性的变化:一项多中心回顾性研究。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-14 DOI: 10.1002/jhm.70133
Nicholas A. Bosch MD, MSc, Anica C. Law MD, MS, Nareg H. Roubinian MD, S. Reza Jafarzadeh DVM, MPVM, PhD, Allan J. Walkey MD, MSc

Background

Transfusion of packed red blood cells (pRBCs) below a hemoglobin concentration of 7.0 g/dL is common, but it is unclear if the timing of transfusion during hospitalization modifies transfusion effectiveness. We sought to determine if effects of pRBC transfusion are heterogenous based on time from hospital admission.

Methods

Multicenter retrospective cohort study including hospitals in the Premier Inc. AI Healthcare Database between 2016 and 2022. Hospital encounters for adults with at least one hemoglobin concentration measured between hospital Days 1–7 were included. For each day, the lowest hemoglobin concentration was identified; patient-days were then separated into seven analytic cohorts based on the day in which a hemoglobin concentration was recorded (index day). We used regression discontinuity to quantify the effect of index day pRBC transfusion versus no transfusion on an outcome of hospital mortality or discharge to hospice (risk difference [RD]) at a hemoglobin concentration threshold of 7.0 g/dL in each cohort.

Results

A total of 2,293,021 index days across 997,277 inpatient encounters were included. The association between pRBC transfusion and hospital mortality or discharge to hospice differed based on days from admission, shifting from benefit on Day 1 (RD: −2.9 [95% CI: −5.9, −0.04] %) to harm on index Days 6 and 7 (Day 6, RD: 3.3 [95% CI: 0.4, 6.1] %; Day 7, RD: 4.1 [95% CI: 0.8, 7.3] %, p-interaction < .0001).

Conclusions

Transfusion during hospitalization was associated with benefit early in hospitalization and harm at later time points.

背景:血红蛋白浓度低于7.0 g/dL的填充红细胞(pRBCs)输注是常见的,但尚不清楚住院期间输注的时机是否会改变输注效果。我们试图确定pRBC输血的影响是否基于住院时间的异质性。方法:多中心回顾性队列研究。2016年至2022年的人工智能医疗保健数据库。在住院第1-7天期间至少测量过一次血红蛋白浓度的成人住院病例纳入研究。每天确定最低血红蛋白浓度;然后根据记录血红蛋白浓度的日期(指标日)将患者日分为七个分析队列。在每个队列中,当血红蛋白浓度阈值为7.0 g/dL时,我们使用回归不连续来量化指标日输血与不输血对医院死亡率或临终关怀出院结果(风险差异[RD])的影响。结果:共纳入997,277例住院患者的2,293,021个索引日。pRBC输注与住院死亡率或出院至临终关怀之间的关联因入院天数而异,从第1天的获益(RD: -2.9 [95% CI: -5.9, -0.04] %)转变为指标第6和7天的危害(第6天,RD: 3.3 [95% CI: 0.4, 6.1] %;第7天,RD: 4.1 [95% CI: 0.8, 7.3] %, p相互作用结论:住院期间输血与住院早期获益和后期伤害相关。
{"title":"Variation in effectiveness of blood transfusion by hospital day: A multicenter retrospective study","authors":"Nicholas A. Bosch MD, MSc,&nbsp;Anica C. Law MD, MS,&nbsp;Nareg H. Roubinian MD,&nbsp;S. Reza Jafarzadeh DVM, MPVM, PhD,&nbsp;Allan J. Walkey MD, MSc","doi":"10.1002/jhm.70133","DOIUrl":"10.1002/jhm.70133","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Transfusion of packed red blood cells (pRBCs) below a hemoglobin concentration of 7.0 g/dL is common, but it is unclear if the timing of transfusion during hospitalization modifies transfusion effectiveness. We sought to determine if effects of pRBC transfusion are heterogenous based on time from hospital admission.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Multicenter retrospective cohort study including hospitals in the Premier Inc. AI Healthcare Database between 2016 and 2022. Hospital encounters for adults with at least one hemoglobin concentration measured between hospital Days 1–7 were included. For each day, the lowest hemoglobin concentration was identified; patient-days were then separated into seven analytic cohorts based on the day in which a hemoglobin concentration was recorded (index day). We used regression discontinuity to quantify the effect of index day pRBC transfusion versus no transfusion on an outcome of hospital mortality or discharge to hospice (risk difference [RD]) at a hemoglobin concentration threshold of 7.0 g/dL in each cohort.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 2,293,021 index days across 997,277 inpatient encounters were included. The association between pRBC transfusion and hospital mortality or discharge to hospice differed based on days from admission, shifting from benefit on Day 1 (RD: −2.9 [95% CI: −5.9, −0.04] %) to harm on index Days 6 and 7 (Day 6, RD: 3.3 [95% CI: 0.4, 6.1] %; Day 7, RD: 4.1 [95% CI: 0.8, 7.3] %, <i>p</i>-interaction &lt; .0001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Transfusion during hospitalization was associated with benefit early in hospitalization and harm at later time points.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"21 2","pages":"133-141"},"PeriodicalIF":2.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A costly gap in safety: Ending the practice of as-needed antihypertensive therapy 代价高昂的安全缺口:终止按需抗高血压治疗。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-13 DOI: 10.1002/jhm.70135
Michael Osnard MD, MS, MPH, Gregory W. Ruhnke MD, MS, MPH
{"title":"A costly gap in safety: Ending the practice of as-needed antihypertensive therapy","authors":"Michael Osnard MD, MS, MPH,&nbsp;Gregory W. Ruhnke MD, MS, MPH","doi":"10.1002/jhm.70135","DOIUrl":"10.1002/jhm.70135","url":null,"abstract":"","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"21 1","pages":"98-99"},"PeriodicalIF":2.3,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of hospital medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1