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Clinical progress note: Phenobarbital in the treatment of alcohol withdrawal syndrome 临床进展注:苯巴比妥治疗酒精戒断综合征。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-29 DOI: 10.1002/jhm.70088
Thad E. Abrams MD, Matthew V. Ronan MD

Alcohol withdrawal syndrome (AWS) is a common condition experienced by hospitalized patients. Practice patterns have evolved over time to include the use of phenobarbital, a barbiturate, as an adjunct to benzodiazepines or as an alternative monotherapy. The American Society of Addiction Medicine (ASAM) has recommended the use of phenobarbital in the management of AWS in certain clinical contexts. The current evidence base for the use of phenobarbital in AWS remains limited, though sufficient to demonstrate safety and efficacy as an alternative to benzodiazepines.

酒精戒断综合征(AWS)是住院患者的常见症状。实践模式随着时间的推移而发展,包括使用苯巴比妥,一种巴比妥类药物,作为苯二氮卓类药物的辅助治疗或作为替代单一疗法。美国成瘾医学协会(ASAM)推荐在某些临床情况下使用苯巴比妥治疗AWS。尽管足以证明苯巴比妥作为苯二氮卓类药物替代品的安全性和有效性,但目前在AWS中使用苯巴比妥的证据基础仍然有限。
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引用次数: 0
Re-envisioning interhospital transfer: A qualitative study exploring alternatives to transfer 重新设想医院间转院:一项探索转院替代方案的定性研究。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-29 DOI: 10.1002/jhm.70083
Stephanie K. Mueller MD, MPH, James D. Harrison MPH, PhD, Amy Yu MD, Caitlin Kelly MPH, Luci K. Leykum MD, MBA, MSc

Background

Interhospital transfer (IHT, the transfer of patients between acute care hospitals) is often undertaken to provide patients with specialized care. However, mounting hospital capacity pressures suggest a need for re-envisioning IHT with consideration of alternatives to transfer in select patients.

Methods

We conducted a qualitative focus group study with key informants involved in IHT, including patient/family representatives, accepting and transferring clinicians, and hospital leadership. We used case examples of distinct IHT scenarios and a semi-structured focus group guide to explore aspects of the IHT process and potential alternative modalities of care. Data were analyzed using thematic analysis, with data coded into sub-themes and higher order themes until thematic saturation was achieved.

Results

We conducted a total of 7 focus groups, involving 6 patient/family representatives, 12 accepting clinicians, 9 transferring clinicians, and 12 hospital leadership from 13 geographically diverse hospitals. Within the higher order theme of “clinically appropriate alternatives to transfer,” we identified several sub-themes, including transferring hospital support, ambulatory alternatives, and patient and organizational risks and benefits. Within the higher order theme of “feasibility and barriers to identified alternatives” we identified three sub-themes, including clinician unease about expansion of clinical scope, lack of healthcare infrastructure to support tele-health care, and limited outpatient capacity.

Discussion

In this qualitative study of key informants involved in IHT, we identified several viable alternatives to IHT and revealed potential barriers that could impede their widespread implementation. These insights provide optimal targets for advancing efforts to develop and operationalize new care models, re-envisioning IHT management.

背景:医院间转院(IHT,病人在急症护理医院之间的转院)通常是为了给病人提供专门的护理。然而,不断增加的医院容量压力表明,需要重新设想IHT,并考虑对选定患者进行转院的替代方案。方法:我们对参与IHT的关键线人进行了定性焦点小组研究,包括患者/家属代表、接受和转移临床医生以及医院领导。我们使用不同IHT情景的案例和半结构化焦点小组指南来探索IHT过程的各个方面和潜在的替代护理模式。使用主题分析来分析数据,将数据编码为子主题和高阶主题,直到主题饱和为止。结果:我们共开展了7个焦点小组,包括来自13家不同地区医院的6名患者/家属代表、12名住院医生、9名转诊医生和12名医院领导。在“临床适宜的转院替代方案”这一更高层次的主题中,我们确定了几个子主题,包括转院支持、门诊替代方案以及患者和组织的风险和收益。在“确定替代方案的可行性和障碍”这一高级主题中,我们确定了三个子主题,包括临床医生对扩大临床范围的不安、缺乏支持远程保健的医疗基础设施以及门诊能力有限。讨论:在这项对参与IHT的关键线人的定性研究中,我们确定了几种可行的IHT替代方案,并揭示了可能阻碍其广泛实施的潜在障碍。这些见解为推进新护理模式的开发和运作、重新设想IHT管理提供了最佳目标。
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引用次数: 0
Clinical guideline highlight: Pediatric refractory constipation 临床指南重点:小儿难治性便秘。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-29 DOI: 10.1002/jhm.70072
Katherine Krause MD, Elizabeth Mertens MD
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引用次数: 0
Team emotional intelligence matters for hospitalists: Unlocking a key driver for performance, learning, and well-being 团队情商对医院医生来说很重要:开启绩效、学习和幸福的关键驱动力。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-28 DOI: 10.1002/jhm.70082
Justin J. Choi MD, MSc

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引用次数: 0
The influence of intergenerational trauma in families of Chinese descent on perceptions of microaggressions 华裔家庭的代际创伤对微侵犯认知的影响。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-26 DOI: 10.1002/jhm.70081
Lucy Cheng, Sonya Tang Girdwood MD, PhD
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引用次数: 0
Novel screening intervention to address food insecurity in hospitalized children 解决住院儿童食物不安全的新型筛选干预措施。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-26 DOI: 10.1002/jhm.70079
Ariel Carpenter MD, Adolfo Molina MD, MSHQS, Mary Orr MD, MPH, DTMH, Cassi Smola MD, Samantha Hanna MD, Chang L. Wu MD, MSCR, Dana Woodruff MPH, Cindy Deerman LCSW, Erin E. Shaughnessy MD, MSHCM

Despite efforts to standardize and optimize screening of hospitalized children for food insecurity, rates of identified food insecurity (4.1%) remained far below the known community rate (18.3%–23.3%). We aimed to improve identification of food insecure families through a novel screening method, utilizing a nonclinical screener at a time uncoupled from admission. The positive food insecurity rate resulting from this screen closely approximated the community rate (18.1%). In addition, the novel screening method better identified Spanish speaking and Latino/Hispanic families with food insecurity, highlighting a disparity in the standard screening process.

尽管努力标准化和优化对住院儿童的粮食不安全筛查,但确定的粮食不安全率(4.1%)仍远低于已知的社区率(18.3%-23.3%)。我们的目的是通过一种新的筛选方法来提高对食品不安全家庭的识别,该方法利用非临床筛选器在入院时进行筛选。这一筛选得出的阳性粮食不安全率与社区率(18.1%)非常接近。此外,新的筛查方法更好地识别了西班牙语和拉丁裔/西班牙裔家庭的粮食不安全状况,凸显了标准筛查过程中的差异。
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引用次数: 0
Comparison of inpatient subspecialty care delivery models: Clinical outcomes and racial disparities in dedicated versus consultative pulmonary care 住院亚专科护理交付模式的比较:专门与咨询肺部护理的临床结果和种族差异。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-23 DOI: 10.1002/jhm.70078
Bhavik P. Patel MD, MSHP, Caitlin B. Clancy MD, MSHP, Scott D. Halpern MD, PhD, Rachel Kohn MD, MSCE

Background

Subspecialty inpatient care is associated with improved outcomes in various clinical settings. However, clinical outcomes and racial disparities between dedicated inpatient pulmonary care and general medicine services with pulmonary consultation remain unknown.

Objective

To compare clinical outcomes between dedicated and consultative inpatient pulmonary care and evaluate whether racial disparities in outcomes differ by care model.

Methods

Retrospective cohort study of 1072 self-identified Black and White adults admitted to dedicated pulmonary or general medicine services with pulmonary consultation (April 2017–February 2020) at an academic medical center. Exposures included the care model, race, and the interaction between the two. Outcomes included hospital length of stay (LOS; modeled as risk of discharge alive using competing risk models), hospital readmissions, and outpatient pulmonary follow-up. We performed multivariable regression models with interaction terms adjusted for demographics, comorbidities, clinical severity, and pulmonary diagnosis.

Results

Dedicated pulmonary service patients had shorter LOS (subdistribution hazard ratio [SHR]: 1.38, 95% confidence interval [CI]: 1.14–1.67, p = .001) and improved 90-day outpatient follow-up (odds ratio [OR]: 1.63, 95% CI: 1.07–2.49, p = .023). The interaction between care model and race demonstrated significantly lower odds of 30-day follow-up among Black patients admitted to the dedicated service versus those with consultations; no other significant racial disparities in outcomes were demonstrated.

Conclusions

Dedicated pulmonary inpatient care was associated with shorter hospital LOS and higher 90-day outpatient follow-up without significant racial disparities in most outcomes. Hospitals could consider pilot-testing dedicated inpatient pulmonary care models, as more work is needed to validate these findings in broader settings.

背景:亚专科住院治疗与各种临床环境下的改善结果相关。然而,临床结果和种族差异在专门的住院肺部护理和一般医学服务与肺部会诊仍然未知。目的:比较专门和咨询住院肺部护理的临床结果,并评估结果的种族差异是否因护理模式而异。方法:回顾性队列研究1072名自我认定的黑人和白人成年人,于2017年4月至2020年2月在一家学术医疗中心接受专门的肺部或普通医学服务并进行肺部咨询。暴露包括护理模式、种族和两者之间的相互作用。结果包括住院时间(LOS);建模为使用竞争风险模型的存活出院风险)、医院再入院和门诊肺部随访。我们进行了多变量回归模型,并根据人口统计学、合并症、临床严重程度和肺部诊断调整了相互作用项。结果:专门肺部服务患者的LOS较短(亚分布风险比[SHR]: 1.38, 95%可信区间[CI]: 1.14-1.67, p = .001),门诊随访90天改善(优势比[OR]: 1.63, 95% CI: 1.07-2.49, p = .023)。护理模式和种族之间的相互作用表明,在接受专门服务的黑人患者中,30天随访的几率明显低于接受咨询的黑人患者;结果中没有其他显著的种族差异。结论:专门的肺部住院治疗与较短的住院时间和较高的90天门诊随访有关,在大多数结果中没有显著的种族差异。医院可以考虑试点测试专门的住院肺部护理模式,因为需要更多的工作来验证这些发现在更广泛的环境中。
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引用次数: 0
Safety in a hybrid hospital-at-home program versus traditional inpatient care: A pragmatic randomized controlled trial 混合在家医院项目与传统住院治疗的安全性:一项实用的随机对照试验。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-21 DOI: 10.1002/jhm.70076
Michael J. Maniaci MD, Lindsey R. Sangaralingham MPH, Emma M. Behnken BA, Melissa S. Hart PMP, CSM, Shealeigh A. Inselman BS, Margaret Paulson DO, Chad R. Nelson MD, Rachel A. Gothot MS, MHA, Yu-Hui H. Chang PhD, MS, Kristine T. Hanson MPH, Yvonne M. Larson Smith BA, Sey V. Oloyede BS, Sarah L. Gifford CCRP, Josh D. Taylor BA, Ajani N. Dunn FACHE, Shannon M. Dunlay MD, MS, Sean C. Dowdy MD, Elizabeth B. Habermann PhD, Wendelyn Bosch MD, Jennifer B. Cowart MD, Xiaoxi Yao PhD, MPH

Background

Hospital-at-home programs (HaH) in the United States have evolved to include a virtual-hybrid delivery model, where all physician encounters are virtual and partnered with a home care team.

Objective

To examine whether a virtual hybrid HaH program enabled by technology has similar clinical outcomes to traditional brick-and-mortar (B&M) hospital care.

Methods

We conducted a pragmatic trial at three hospitals, randomizing 1150 acutely ill patients requiring hospital care between July 10, 2023, and October 31, 2023 one-to-one into two groups: intervention (HaH) and control (B&M). The primary analysis was an intention-to-treat non-inferiority analysis of the primary outcome, which was a composite of 30-day all-cause mortality and unplanned readmissions. Secondary outcomes included 30-day readmission, all-cause mortality, and patient experience.

Results

The mean age was 67.8 (standard deviation [SD] 16.3) years, and 52.2% were female. The primary outcome occurred in 99 (17.3%) HaH patients and 114 (19.8%) B&M patients (odds ratio [OR] 0.85, 95% confidence interval [CI] 0.63–1.14, p = .28), meeting the non-inferiority criterion. Thirty-day unplanned readmission occurred in 84 (14.7%) HaH patients and 101 (17.5%) B&M patients (OR 0.81, 95% CI 0.59–1.11, p = .19). Thirty-day all-cause mortality occurred in 25 (4.4%) HaH patients and 19 (3.3%) B&M patients (OR 1.34, 95% CI 0.73–2.46, p = .35). No HaH patients died while receiving their hospital care at home. HaH program was associated with a higher likelihood of patients reporting feeling extremely comfortable or very comfortable (84.4% HaH; 60.9% B&M, p = .001).

Conclusion

A hybrid HaH model is a safe and comfortable alternative to traditional B&M hospital care.

背景:美国的居家医院项目(HaH)已经发展到包括虚拟-混合交付模式,在这种模式下,所有医生的接触都是虚拟的,并与家庭护理团队合作。目的:研究技术支持的虚拟混合HaH程序是否具有与传统实体(B&M)医院护理相似的临床结果。方法:我们在三家医院进行了一项实用试验,将1150名在2023年7月10日至2023年10月31日期间需要住院治疗的急性病人随机分为两组:干预组(HaH)和对照组(B&M)。主要分析是对主要结局进行意向治疗非劣效性分析,主要结局是30天全因死亡率和计划外再入院的综合结果。次要结局包括30天再入院、全因死亡率和患者经历。结果:患者平均年龄67.8岁(标准差[SD] 16.3),女性占52.2%。主要结局发生在99例(17.3%)HaH患者和114例(19.8%)B&M患者中(优势比[OR] 0.85, 95%可信区间[CI] 0.63-1.14, p = 0.28),符合非劣效性标准。有84例(14.7%)ha患者和101例(17.5%)B&M患者发生30天意外再入院(OR 0.81, 95% CI 0.59-1.11, p = 0.19)。25例ha患者(4.4%)和19例B&M患者(3.3%)发生30天全因死亡率(OR 1.34, 95% CI 0.73-2.46, p = 0.35)。没有病人在家中接受医院护理时死亡。HaH方案与患者报告感觉极度舒适或非常舒适的可能性较高相关(84.4% HaH;60.9% B&M, p = .001)。结论:混合型体外循环模式是传统B&M医院护理的一种安全、舒适的选择。
{"title":"Safety in a hybrid hospital-at-home program versus traditional inpatient care: A pragmatic randomized controlled trial","authors":"Michael J. Maniaci MD,&nbsp;Lindsey R. Sangaralingham MPH,&nbsp;Emma M. Behnken BA,&nbsp;Melissa S. Hart PMP, CSM,&nbsp;Shealeigh A. Inselman BS,&nbsp;Margaret Paulson DO,&nbsp;Chad R. Nelson MD,&nbsp;Rachel A. Gothot MS, MHA,&nbsp;Yu-Hui H. Chang PhD, MS,&nbsp;Kristine T. Hanson MPH,&nbsp;Yvonne M. Larson Smith BA,&nbsp;Sey V. Oloyede BS,&nbsp;Sarah L. Gifford CCRP,&nbsp;Josh D. Taylor BA,&nbsp;Ajani N. Dunn FACHE,&nbsp;Shannon M. Dunlay MD, MS,&nbsp;Sean C. Dowdy MD,&nbsp;Elizabeth B. Habermann PhD,&nbsp;Wendelyn Bosch MD,&nbsp;Jennifer B. Cowart MD,&nbsp;Xiaoxi Yao PhD, MPH","doi":"10.1002/jhm.70076","DOIUrl":"10.1002/jhm.70076","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Hospital-at-home programs (HaH) in the United States have evolved to include a virtual-hybrid delivery model, where all physician encounters are virtual and partnered with a home care team.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To examine whether a virtual hybrid HaH program enabled by technology has similar clinical outcomes to traditional brick-and-mortar (B&amp;M) hospital care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a pragmatic trial at three hospitals, randomizing 1150 acutely ill patients requiring hospital care between July 10, 2023, and October 31, 2023 one-to-one into two groups: intervention (HaH) and control (B&amp;M). The primary analysis was an intention-to-treat non-inferiority analysis of the primary outcome, which was a composite of 30-day all-cause mortality and unplanned readmissions. Secondary outcomes included 30-day readmission, all-cause mortality, and patient experience.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age was 67.8 (standard deviation [SD] 16.3) years, and 52.2% were female. The primary outcome occurred in 99 (17.3%) HaH patients and 114 (19.8%) B&amp;M patients (odds ratio [OR] 0.85, 95% confidence interval [CI] 0.63–1.14, <i>p</i> = .28), meeting the non-inferiority criterion. Thirty-day unplanned readmission occurred in 84 (14.7%) HaH patients and 101 (17.5%) B&amp;M patients (OR 0.81, 95% CI 0.59–1.11, <i>p</i> = .19). Thirty-day all-cause mortality occurred in 25 (4.4%) HaH patients and 19 (3.3%) B&amp;M patients (OR 1.34, 95% CI 0.73–2.46, <i>p</i> = .35). No HaH patients died while receiving their hospital care at home. HaH program was associated with a higher likelihood of patients reporting feeling extremely comfortable or very comfortable (84.4% HaH; 60.9% B&amp;M, <i>p</i> = .001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>A hybrid HaH model is a safe and comfortable alternative to traditional B&amp;M hospital care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"20 11","pages":"1174-1184"},"PeriodicalIF":2.3,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical progress note: Pertussis 临床进展:百日咳。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-19 DOI: 10.1002/jhm.70080
Samantha Hanna MD, MPH, Nicole Samies DO

Pertussis, commonly known as whooping cough, is a vaccine-preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of hospitalization and death, but adolescents and adults play an important role in pertussis transmission and outbreaks. Prompt recognition and diagnosis remain critical for hospitalists in the management of pertussis disease and prevention.

百日咳,俗称百日咳,是一种疫苗可预防的呼吸道疾病,由于接种率下降和免疫力下降,发病率上升。最严重的疾病过程发生在未接种疫苗或未完全接种疫苗的2个月以下婴儿中,占住院和死亡的最大负担,但青少年和成年人在百日咳传播和暴发中发挥重要作用。及时识别和诊断仍然是医院在百日咳疾病的管理和预防的关键。
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引用次数: 0
Code status discussions with families of children with medically complexity need to happen sooner 需要尽早与医疗状况复杂的儿童的家庭讨论代码状况。
IF 2.3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-05-19 DOI: 10.1002/jhm.70075
Lauren Agoratus MA
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引用次数: 0
期刊
Journal of hospital medicine
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