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Surgical management of gallstone ileus: impact of frailty and concurrent cholecystectomy 胆石性肠梗阻的外科治疗:虚弱和同期胆囊切除术的影响。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-19 DOI: 10.1016/j.gassur.2025.102283
Dakota Thompson , Julia Frebault , Catherine Tran , Jeremy Chang , Pridvi Kandagatla , Imran Hassan , Paolo Goffredo
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引用次数: 0
Preoperative risk factors associated with hypoglycemia after bariatric surgery: a systematic review and meta-analysis 术前与减肥手术后低血糖相关的危险因素:一项系统回顾和荟萃分析。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-19 DOI: 10.1016/j.gassur.2025.102288
Lisa Milena Anabela, Syifa Salsabila, Wilbert Huang, Muhammad Irfan Fathoni, Aklila Qurrota A’ini Sumardi, Cynthia Parameswari

Background

Hypoglycemia is a common adverse outcome after bariatric surgery. Preoperative factors are important to predict worse hypoglycemic incidence. This study aimed to evaluate preoperative risk factors associated with the incidence of hypoglycemia after bariatric surgery.

Methods

A systematic search was performed across 3 databases until September 2024. Hypoglycemia was defined as the presence of neuroglycopenic and/or neurogenic signs and symptoms, accompanied by a blood glucose level of <3.0 mmol/L (54 mg/dL) with resolution after glucose ingestion.

Results

A total of 11 observational and randomized controlled trial studies, which were composed of 8428 patients, were included in the study. Female sex (odds ratio [OR] 1.56, [95% CI, 1.28–1.89]; P <.00001; I2 = 0%) and body mass index (BMI; OR, 1.03 [95% CI, 1.01–1.05]; P =.002; I2 = 0%) were associated with an increased risk of developing hypoglycemia after bariatric surgery. Preoperative fasting blood glucose value was associated with increased odds of hypoglycemia (OR, 3.16 [95% CI, 1.34–7.44]; P =.008; I2 = 83%; r, −492 [range, −0.572 to −402]; P =.000). Age, hemoglobin A1C level, high-density lipoprotein cholesterol, triglycerides, and preoperative smoking status were not significantly associated with the increased odds of postbariatric hypoglycemia (PBH) or linearly correlated with the outcome (P >.05).

Conclusion

Female sex, BMI, and preoperative fasting blood glucose level were significantly associated with the incidence of PBH. A lower preoperative fasting blood glucose level increased the risk of PBH.
背景:低血糖是减肥手术后常见的不良后果。术前因素对于预测更严重的低血糖发生率很重要。本研究旨在评估术前与减肥手术后低血糖发生率相关的危险因素。方法:截至2024年9月,对3个数据库进行系统检索。低血糖被定义为出现神经性低血糖和/或神经源性体征和症状,并伴有血糖水平。结果:纳入了11项观察性和随机对照试验,包括8428例患者。女性(OR 1.56 [1.28, 1.89]; p值< 0.00001;I2 0%)和BMI (OR 1.03 [1.01, 1.05]; p值0.002;I2 0%)与减肥手术后低血糖发生风险增加相关。术前空腹血糖值明显增高,与低血糖相关(OR为3.16 [1.34,7.44]p值0.008 I2 83%; r为-492 [-0.572,-402]p值0.000)。术前年龄、HbA1C水平、HDL胆固醇、甘油三酯和吸烟状况与增重后低血糖(PBH)发生率无统计学意义的增加相关,也与预后无线性相关(p值bb0 0.05)。结论:女性性别、BMI、术前空腹血糖与PBH的发生率显著相关。术前较低的空腹血糖会增加PBH的风险。
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引用次数: 0
Redo rates and outcomes of gastric peroral endoscopic myotomy vs pyloroplasty for gastroparesis: a retrospective analysis 胃轻瘫的经口胃镜下肌切开术(G-POEM)与幽门成形术的重做率和结果:回顾性分析。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-18 DOI: 10.1016/j.gassur.2025.102286
Chamanthi Konidala , Cameron Dabbs , Ryan Shargo , Isaac Poonen-Honig , Pavani Peddi , Camille Thélin , Salvatore Docimo Jr , Rebecca Klam , Joseph Sujka

Background

Gastroparesis is a chronic gastrointestinal (GI) motility disorder that is defined by objectively delayed gastric emptying of solids in the absence of mechanical obstruction. Gastroparesis presents as a syndrome marked by a range of upper GI symptoms, most commonly nausea, vomiting, early satiety, bloating, belching, and upper abdominal discomfort or pain. Pylorus-targeting approaches have been a common management for gastroparesis, with gastric peroral endoscopic myotomy (G-POEM) and pyloroplasty being effective surgical options. However, comparative data on redo procedure rates and outcomes remain limited. This study aimed to compare the frequency, timing, and clinical outcomes of redo interventions after G-POEM vs pyloroplasty in patients with refractory gastroparesis, addressing the current gap in comparative data to help guide long-term procedural decision-making.

Methods

A retrospective chart review was conducted on patients who underwent G-POEM or pyloroplasty from 2019 to 2024. Data included redo rates, time to reintervention, and postintervention outcomes. Statistical analyses were performed using appropriate tests for categorical and continuous variables.

Results

Among 173 patients (85 who underwent G-POEM and 88 who underwent pyloroplasty), those who underwent pyloroplasty were more likely to have preoperative patient-reported esophageal reflux (P <.001) and concurrent procedures (P <.001). Of note, 42 patients (24%) required redo procedures (G-POEM: 52.4%; pyloroplasty: 47.6%). The mean time to redo was 383.18 days (P =.156). Although the reintervention rates were similar (P =.770), patients who underwent G-POEM more often underwent secondary pyloroplasty, whereas those who underwent pyloroplasty more frequently received gastric neurostimulators (P =.012). Symptom improvement was comparable (P =.870), with 51% reporting relief and 21% achieving resolution.

Conclusion

G-POEM and pyloroplasty have similar redo rates but differ in terms of the types of secondary intervention, highlighting the need for individualized treatment planning.
背景:胃轻瘫是一种慢性胃肠运动障碍,客观定义为在没有机械阻塞的情况下胃排空固体物质延迟。它表现为一种以一系列上消化道症状为特征的综合征,最常见的是恶心、呕吐、早饱、腹胀、打嗝和上腹部不适或疼痛。幽门靶向入路是胃轻瘫的常见治疗方法,经口胃镜下肌切开术(G-POEM)和幽门成形术是有效的手术选择。然而,关于重做手术率和结果的比较数据仍然有限。目的:比较难治性胃轻瘫患者G-POEM与幽门成形术后重做干预的频率、时间和临床结果,解决目前比较数据的空白,以帮助指导长期手术决策。方法:回顾性分析2019 - 2024年行G-POEM或幽门成形术患者的病历。数据包括重做率、再干预时间和干预后结果。采用适当的分类和连续变量检验进行统计分析。结果:173例患者(85例G-POEM, 88例幽门成形术)中,接受幽门成形术的患者更有可能发生术前患者报告的食管反流(p < 0.001)和同期手术(p < 0.001)。42例患者(24%)需要重做手术(G-POEM: 52.4%,幽门成形术:47.6%)。平均重做时间为383.18天(p = 0.156)。虽然再干预率相似(p = 0.770),但G-POEM患者更常接受二次幽门成形术,而幽门成形术患者更常接受胃神经刺激剂(p = 0.012)。症状改善具有可比性(p = 0.870), 51%的患者报告缓解,21%的患者获得缓解。结论:G-POEM和幽门成形术的重做率相似,但在二次干预类型上存在差异,突出了个性化治疗计划的必要性。
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引用次数: 0
Restoring bowel continuity after extended left colectomy: a comparative study of the retroileal window and Deloyers techniques 延长左结肠切除术后恢复肠连续性:回肠后窗和Deloyers技术的比较研究。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-17 DOI: 10.1016/j.gassur.2025.102284
Lukas Schabl , Lucas F. Sobrado , Imran Khan , Kamil Erozkan , Tarkan Jäger , Scott R. Steele , Tracy L. Hull

Background

Establishing an anastomosis after an extended left hemicolectomy can be challenging due to insufficient colonic reach. Surgical options include the Deloyers technique (DT) and the retroileal window technique (RIWT). The primary objective was to compare the safety and functional outcomes of these restorative techniques.

Methods

This retrospective cohort analysis used prospectively collected data on postoperative quality of life (QoL) and bowel function. Adult patients who underwent either RIWT or DT at a tertiary center between 1995 and 2023 were included in the study. The primary outcomes were complications, patient-reported bowel function, and QoL, which were assessed using validated questionnaires.

Results

RIWT was performed in 87 patients, and DT was performed in 97 patients. Cancer was the most common indication in both groups. RIWT occurred more during index operation (64.4% in the RIWT group vs 33.0% in the DT group; P <.001), whereas DT had higher rates of low anastomosis (57.7% in the DT group vs 27.6% in the RIWT group; P <.001) and protective stomas (69.1% in the DT group vs 19.5% in the RIWT group; P <.001). RIWT had higher odds of postoperative ileus (odds ratio, 7.2 [95% CI, 1.7–30.2]; P =.007). Other postoperative complications, including Clavien-Dindo grade > II events, were comparable. DT showed more dietary and social restrictions and bowel movements at night and per 24 h on univariate analysis, although not significant on multivariate analysis. The Wexner continence scores and QoL were similar between the groups.

Conclusion

RIWT and DT are safe and effective techniques for achieving tension-free anastomosis after extended left colectomy. Given the comparable complication rates and functional outcomes, the choice of surgical technique should be based on intraoperative findings and surgeon expertise.
背景:扩大左结肠切除术后建立吻合是具有挑战性的,因为结肠到达不足。手术选择包括Deloyers技术(DT)和回肠后窗技术(RIWT)。主要目的是比较这些修复技术的安全性和功能结果。方法:回顾性队列分析采用前瞻性收集的术后生活质量和肠功能数据。纳入了1995-2023年间在三级中心接受RIWT或DT治疗的成年患者。主要结果是并发症、患者报告的肠道功能和生活质量,使用有效的问卷进行评估。结果:87例患者行RIWT, 97例行DT。癌症是两组中最常见的适应症。指数手术时RIWT发生率较高(64.4%比33%,p < 0.001), DT手术低吻合率(57.7%比27.6%,p < 0.001)和保护性造口率(69.1%比19.5%,p < 0.001)较高。RIWT术后肠梗阻发生率较高(OR 7.2, 95% CI 1.7 ~ 30.2, p=0.007)。其他术后并发症,包括Clavien-Dindo级> II事件,具有可比性。单因素分析显示,DT在夜间和每24小时有更多的饮食和社会限制和排便,但多因素分析不显著。Wexner控制评分和生活质量在两组之间相似。结论:RIWT和DT是延长左结肠切除术后实现无张力吻合的安全有效的技术。考虑到比较的并发症发生率和功能结果,技术的选择应基于术中发现和外科医生的专业知识。摘要:本研究比较了回肠后窗技术(RIWT)和Deloyers技术(DT)在延长左结肠切除术后恢复肠道连续性方面的作用。两种手术均安全,并发症发生率均可接受。功能结果和生活质量具有可比性。技术选择应基于术中评估和外科医生的经验。意义声明:由于结肠长度不足,延长左结肠切除术后建立吻合可能会有问题。解决这一问题的手术选择包括Deloyers手术和回肠后窗手术。以前没有任何调查显示过如此大量的患者,也没有任何研究进行过这类比较分析。
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引用次数: 0
Utility and safety of near-infrared fluorescent marking clips for tumor localization in robot-assisted laparoscopic gastric cancer surgery 近红外荧光标记夹在机器人辅助腹腔镜胃癌手术中肿瘤定位的实用性和安全性。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-12 DOI: 10.1016/j.gassur.2025.102280
Koshi Kumagai , Masashi Yoshida , Hiroki Ishida , Naoki Ishizuka , Manabu Ohashi , Rie Makuuchi , Masaru Hayami , Satoshi Ida , Yohei Ikenoyama , Ken Namikawa , Yoshitaka Tokai , Shoichi Yoshimizu , Yusuke Horiuchi , Akiyoshi Ishiyama , Toshiyuki Yoshio , Toshiaki Hirasawa , Junko Fujisaki , Souya Nunobe

Purpose

Precise resection margins are crucial in gastric cancer surgery to optimize oncological outcomes and reduce postoperative functional disorders. Fluorescent marking clips (ZEOCLIP FS; Zeon Medical Co, Ltd) have demonstrated potential in improving resection line accuracy during laparoscopic gastrectomy. However, the original ZEOCLIP FS contained insufficient fluorescent dye, limiting its visibility with the Firefly mode of the da Vinci Surgical System. To address this limitation, a new version with increased dye concentration, the ZEOCLIP FS Marker, was developed. This study aimed to evaluate the utility and safety of the enhanced ZEOCLIP FS Marker in robot-assisted gastric cancer surgery.

Methods

A prospective observational study was conducted in 20 patients diagnosed with gastric cancer (cT1-T4aNanyM0). Fluorescent clips were preoperatively placed along the intended resection margins, and the Firefly mode was used intraoperatively to detect the clips. The primary endpoint was the detection rate, defined as the proportion of cases in which all preoperatively placed clips were identified under fluorescence. The secondary endpoints included detection time, thread-to-clip distance, and complications.

Results

The detection rate of the clips under fluorescence was 75.0% (90% CI, 54.4%–89.6%). At least 1 fluorescent clip was detected in all patients (20/20), facilitating approximate tumor localization. Of the 51 clips placed, 45 (88.2%) were identified under fluorescence. The median thread-to-clip distance was 3 mm (range, 0–13). Clip-related complications were minimal, with 1 case of postoperative anastomotic leakage and 2 unrelated complications.

Conclusion

The enhanced ZEOCLIP FS Marker seems effective and safe for marking gastric transection lines in robot-assisted surgery. Further prospective interventional studies are warranted to confirm whether the use of fluorescent clips can reduce the reliance on intraoperative endoscopy.
目的:在胃癌手术中,精确切除边缘是优化肿瘤预后和减少术后功能障碍的关键。荧光标记夹(ZEOCLIP FS)在腹腔镜胃切除术中被证明具有提高切除线准确性的潜力。然而,最初的ZEOCLIP FS含有的荧光染料不足,限制了它在达芬奇手术系统的萤火虫模式下的可见性。为了解决这一限制,开发了一种增加染料浓度的新版本ZEOCLIP FS Marker。本研究评估了增强型ZEOCLIP FS标记在机器人辅助胃癌手术中的效用和安全性。方法:对20例诊断为胃癌(cT1-T4aNanyM0)的患者进行前瞻性观察研究。术前沿预定切除边缘放置荧光夹,术中使用Firefly模式检测荧光夹。主要终点是检出率,定义为所有术前放置的夹子在荧光下被识别的病例的比例。次要终点包括检测时间、线-夹距离和并发症。结果:荧光检测片段的检出率为75%(90%置信区间:54.4% ~ 89.6%)。所有患者(20/20)至少检测到一个荧光片段,有助于肿瘤的大致定位。在放置的51个片段中,45个(88.2%)在荧光下被识别。线与夹的中间距离为3mm(范围0-13mm)。夹钳相关并发症极少,术后吻合口瘘1例,无相关并发症2例。结论:增强的ZEOCLIP FS标记在机器人辅助手术中标记胃横断线是有效和安全的。需要进一步的前瞻性介入研究来证实荧光夹是否可以减少对术中内窥镜的依赖。
{"title":"Utility and safety of near-infrared fluorescent marking clips for tumor localization in robot-assisted laparoscopic gastric cancer surgery","authors":"Koshi Kumagai ,&nbsp;Masashi Yoshida ,&nbsp;Hiroki Ishida ,&nbsp;Naoki Ishizuka ,&nbsp;Manabu Ohashi ,&nbsp;Rie Makuuchi ,&nbsp;Masaru Hayami ,&nbsp;Satoshi Ida ,&nbsp;Yohei Ikenoyama ,&nbsp;Ken Namikawa ,&nbsp;Yoshitaka Tokai ,&nbsp;Shoichi Yoshimizu ,&nbsp;Yusuke Horiuchi ,&nbsp;Akiyoshi Ishiyama ,&nbsp;Toshiyuki Yoshio ,&nbsp;Toshiaki Hirasawa ,&nbsp;Junko Fujisaki ,&nbsp;Souya Nunobe","doi":"10.1016/j.gassur.2025.102280","DOIUrl":"10.1016/j.gassur.2025.102280","url":null,"abstract":"<div><h3>Purpose</h3><div>Precise resection margins are crucial in gastric cancer surgery to optimize oncological outcomes and reduce postoperative functional disorders. Fluorescent marking clips (ZEOCLIP FS; Zeon Medical Co, Ltd) have demonstrated potential in improving resection line accuracy during laparoscopic gastrectomy. However, the original ZEOCLIP FS contained insufficient fluorescent dye, limiting its visibility with the Firefly mode of the da Vinci Surgical System. To address this limitation, a new version with increased dye concentration, the ZEOCLIP FS Marker, was developed. This study aimed to evaluate the utility and safety of the enhanced ZEOCLIP FS Marker in robot-assisted gastric cancer surgery.</div></div><div><h3>Methods</h3><div>A prospective observational study was conducted in 20 patients diagnosed with gastric cancer (cT1-T4aNanyM0). Fluorescent clips were preoperatively placed along the intended resection margins, and the Firefly mode was used intraoperatively to detect the clips. The primary endpoint was the detection rate, defined as the proportion of cases in which all preoperatively placed clips were identified under fluorescence. The secondary endpoints included detection time, thread-to-clip distance, and complications.</div></div><div><h3>Results</h3><div>The detection rate of the clips under fluorescence was 75.0% (90% CI, 54.4%–89.6%). At least 1 fluorescent clip was detected in all patients (20/20), facilitating approximate tumor localization. Of the 51 clips placed, 45 (88.2%) were identified under fluorescence. The median thread-to-clip distance was 3 mm (range, 0–13). Clip-related complications were minimal, with 1 case of postoperative anastomotic leakage and 2 unrelated complications.</div></div><div><h3>Conclusion</h3><div>The enhanced ZEOCLIP FS Marker seems effective and safe for marking gastric transection lines in robot-assisted surgery. Further prospective interventional studies are warranted to confirm whether the use of fluorescent clips can reduce the reliance on intraoperative endoscopy.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 1","pages":"Article 102280"},"PeriodicalIF":2.4,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145523444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body mass index and survival after surgery for gastric adenocarcinoma: a population-based nationwide cohort study in Finland 体重指数与胃腺癌术后生存率——芬兰一项基于人群的全国队列研究
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-12 DOI: 10.1016/j.gassur.2025.102282
Aapo Jalkanen , Arto Kokkola , Johanna Louhimo , Olli Helminen , Mika Helmiö , Heikki Huhta , Anna Junttila , Raija Kallio , Vesa Koivukangas , Simo Laine , Elina Lietzen , Sanna Meriläinen , Vesa-Matti Pohjanen , Tuomo Rantanen , Ari Ristimäki , Jari V. Räsänen , Juha Saarnio , Eero Sihvo , Vesa Toikkanen , Tuula Tyrväinen , Joonas H. Kauppila

Background

Gastric cancer surgery is associated with significant morbidity. Obesity is a risk factor for short-term complications. However, previous studies on the role of body mass index (BMI) as a predictor of long-term survival have conflicting results, and contemporary population-based data in the Western population are lacking. This study aimed to compare the long-term survival after gastric cancer surgery among patients who were underweight (BMI of <18.5 kg/m2), those with normal weight (BMI of 18.5–24.9 kg/m2), those who were overweight (BMI of 25.0–29.9 kg/m2), and those who were obese (BMI of >30.0 kg/m2).

Methods

This was a population-based, retrospective, nationwide cohort study in Finland using the Finnish National Esophago-Gastric Cancer Cohort. Patients who underwent gastrectomy with available height and weight data were included. A Cox regression model was used to calculate the 95% CI for 6-month to 5-year survival and 6-month survival, which was adjusted for age, sex (assigned), year of surgery, Charlson Comorbidity Index, pathological p/yp stage, neoadjuvant therapy, type of resection, and Lauren histological type.

Results

Overall, 1647 patients who underwent gastrectomy for gastric cancer were identified. Of the patients, 64 (3.9%) were underweight, 735 (44.6%) had normal weight, 584 (35.5%) were overweight, and 264 (16.0%) were obese. In the first 6 months, mortality was higher in the overweight group (hazard ratio [HR], 1.663 [95% CI, 1.158–2.389]) than in the normal weight group. However, 6-month to 5-year mortality was the highest in the underweight group (HR, 1.426 [95% CI, 1.019–1.994]) and decreased with increasing BMI (HR, 0.820 [95% CI, 0.708–0.949]). Patients with obesity had the best prognosis (HR, 0.798 [95% CI, 0.655–0.971]).

Conclusion

In this population-based study, higher BMI was associated with better long-term survival after gastric cancer surgery, somewhat offset by higher mortality during the first postoperative months, with patients with obesity having the best overall survival.
目的:比较体重过轻(体重指数(BMI) 30)胃癌患者术后的长期生存率。背景:胃癌手术与显著的发病率相关。肥胖是短期并发症的危险因素;然而,先前关于身体质量指数(BMI)作为长期生存预测指标的研究存在矛盾,当代西方人群中基于人群的数据缺乏。方法:这是一项基于人群的、回顾性的、芬兰全国队列研究,使用芬兰国家食管胃癌队列(FINEGO)。纳入有身高和体重资料的胃切除术患者。采用Cox回归模型计算6个月至5年生存率的95% CI,以及经年龄、性别、手术年份、Charlson合并症指数、病理p/yp分期、新辅助治疗、切除类型和Lauren组织学类型调整后的6个月生存率。结果:共发现1647例胃癌患者行胃切除术。体重不足64例(3.9%),正常体重735例(44.6%),超重584例(35.5%),肥胖264例(16.0%)。在前六个月,超重组的死亡率高于正常体重组(HR 1.663, 95% CI 1.158-2.389)。然而,体重不足患者的6个月至5年死亡率最高(与正常体重相比,HR为1.426,95% CI为1.019-1.994),并随着BMI的增加而降低(HR为820,95% CI为708- 0.949,与正常体重相比,超重)。肥胖患者预后最佳(HR.798 95% CI.655- 0.971)。结论:在这项基于人群的研究中,较高的BMI与胃癌手术后较好的长期生存相关,在一定程度上抵消了术后头几个月较高的死亡率,肥胖患者的总生存期最好。
{"title":"Body mass index and survival after surgery for gastric adenocarcinoma: a population-based nationwide cohort study in Finland","authors":"Aapo Jalkanen ,&nbsp;Arto Kokkola ,&nbsp;Johanna Louhimo ,&nbsp;Olli Helminen ,&nbsp;Mika Helmiö ,&nbsp;Heikki Huhta ,&nbsp;Anna Junttila ,&nbsp;Raija Kallio ,&nbsp;Vesa Koivukangas ,&nbsp;Simo Laine ,&nbsp;Elina Lietzen ,&nbsp;Sanna Meriläinen ,&nbsp;Vesa-Matti Pohjanen ,&nbsp;Tuomo Rantanen ,&nbsp;Ari Ristimäki ,&nbsp;Jari V. Räsänen ,&nbsp;Juha Saarnio ,&nbsp;Eero Sihvo ,&nbsp;Vesa Toikkanen ,&nbsp;Tuula Tyrväinen ,&nbsp;Joonas H. Kauppila","doi":"10.1016/j.gassur.2025.102282","DOIUrl":"10.1016/j.gassur.2025.102282","url":null,"abstract":"<div><h3>Background</h3><div>Gastric cancer surgery is associated with significant morbidity. Obesity is a risk factor for short-term complications. However, previous studies on the role of body mass index (BMI) as a predictor of long-term survival have conflicting results, and contemporary population-based data in the Western population are lacking. This study aimed to compare the long-term survival after gastric cancer surgery among patients who were underweight (BMI of &lt;18.5 kg/m<sup>2</sup>), those with normal weight (BMI of 18.5–24.9 kg/m<sup>2</sup>), those who were overweight (BMI of 25.0–29.9 kg/m<sup>2</sup>), and those who were obese (BMI of &gt;30.0 kg/m<sup>2</sup>).</div></div><div><h3>Methods</h3><div>This was a population-based, retrospective, nationwide cohort study in Finland using the Finnish National Esophago-Gastric Cancer Cohort. Patients who underwent gastrectomy with available height and weight data were included. A Cox regression model was used to calculate the 95% CI for 6-month to 5-year survival and 6-month survival, which was adjusted for age, sex (assigned), year of surgery, Charlson Comorbidity Index, pathological p/yp stage, neoadjuvant therapy, type of resection, and Lauren histological type.</div></div><div><h3>Results</h3><div>Overall, 1647 patients who underwent gastrectomy for gastric cancer were identified. Of the patients, 64 (3.9%) were underweight, 735 (44.6%) had normal weight, 584 (35.5%) were overweight, and 264 (16.0%) were obese. In the first 6 months, mortality was higher in the overweight group (hazard ratio [HR], 1.663 [95% CI, 1.158–2.389]) than in the normal weight group. However, 6-month to 5-year mortality was the highest in the underweight group (HR, 1.426 [95% CI, 1.019–1.994]) and decreased with increasing BMI (HR, 0.820 [95% CI, 0.708–0.949]). Patients with obesity had the best prognosis (HR, 0.798 [95% CI, 0.655–0.971]).</div></div><div><h3>Conclusion</h3><div>In this population-based study, higher BMI was associated with better long-term survival after gastric cancer surgery, somewhat offset by higher mortality during the first postoperative months, with patients with obesity having the best overall survival.</div></div>","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 1","pages":"Article 102282"},"PeriodicalIF":2.4,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145523438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invited commentary on “Prospective evaluation of the novel BADCAL score for predicting colorectal anastomotic leak unicorn hunt: searching for the ideal tool to predict and identify anastomotic leak” 预测结直肠吻合口瘘的新型BADCAL评分的前瞻性评价独角兽狩猎:寻找预测和识别吻合口瘘的理想工具。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.gassur.2025.102281
Frank A. DiSilvio, Terrah Paul Olson
{"title":"Invited commentary on “Prospective evaluation of the novel BADCAL score for predicting colorectal anastomotic leak unicorn hunt: searching for the ideal tool to predict and identify anastomotic leak”","authors":"Frank A. DiSilvio,&nbsp;Terrah Paul Olson","doi":"10.1016/j.gassur.2025.102281","DOIUrl":"10.1016/j.gassur.2025.102281","url":null,"abstract":"","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 1","pages":"Article 102281"},"PeriodicalIF":2.4,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145504909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ciliated foregut cyst of the biliary hilum mimicking choledochal cyst 胆道门纤毛前肠囊肿,酷似胆总管囊肿。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-07 DOI: 10.1016/j.gassur.2025.102278
Olivia Sears, Samantha M. Ruff, Victor M. Zaydfudim
{"title":"Ciliated foregut cyst of the biliary hilum mimicking choledochal cyst","authors":"Olivia Sears,&nbsp;Samantha M. Ruff,&nbsp;Victor M. Zaydfudim","doi":"10.1016/j.gassur.2025.102278","DOIUrl":"10.1016/j.gassur.2025.102278","url":null,"abstract":"","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 1","pages":"Article 102278"},"PeriodicalIF":2.4,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145482228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conversion to permanent stoma due to poor bowel function after proctectomy with coloanal anastomosis for rectal cancer 结肠肛管吻合术治疗直肠癌直肠切除术后肠功能差致永久造口。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-05 DOI: 10.1016/j.gassur.2025.102277
Reena S. Suresh, Shannon N. Radomski, Miloslawa Stem, Michael Consul, Angelos Papanikolaou, Sophia Y. Chen, Susan L. Gearhart, Alodia Gabre-Kidan
{"title":"Conversion to permanent stoma due to poor bowel function after proctectomy with coloanal anastomosis for rectal cancer","authors":"Reena S. Suresh,&nbsp;Shannon N. Radomski,&nbsp;Miloslawa Stem,&nbsp;Michael Consul,&nbsp;Angelos Papanikolaou,&nbsp;Sophia Y. Chen,&nbsp;Susan L. Gearhart,&nbsp;Alodia Gabre-Kidan","doi":"10.1016/j.gassur.2025.102277","DOIUrl":"10.1016/j.gassur.2025.102277","url":null,"abstract":"","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 1","pages":"Article 102277"},"PeriodicalIF":2.4,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145470920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucagon-like peptide-1 receptor agonists: reshaping the surgical paradigm in obesity and gastrointestinal disease GLP-1受体激动剂:重塑肥胖和胃肠道疾病的手术模式。
IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2025-11-05 DOI: 10.1016/j.gassur.2025.102276
Vipul D. Yagnik , Prema Ram Choudhary
{"title":"Glucagon-like peptide-1 receptor agonists: reshaping the surgical paradigm in obesity and gastrointestinal disease","authors":"Vipul D. Yagnik ,&nbsp;Prema Ram Choudhary","doi":"10.1016/j.gassur.2025.102276","DOIUrl":"10.1016/j.gassur.2025.102276","url":null,"abstract":"","PeriodicalId":15893,"journal":{"name":"Journal of Gastrointestinal Surgery","volume":"30 1","pages":"Article 102276"},"PeriodicalIF":2.4,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145470934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Gastrointestinal Surgery
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