Pub Date : 2025-11-21DOI: 10.1016/j.healun.2025.08.014
Lorraine B. Ware MD , Tatsuki Koyama PhD , Ciara M. Shaver MD, PhD , Michael A. Matthay MD
{"title":"Reply to “Comments and opinions regarding ‘A randomized trial of open lung protective ventilation compared to conventional mechanical ventilation in deceased organ donors’ by Ware LB et al.”","authors":"Lorraine B. Ware MD , Tatsuki Koyama PhD , Ciara M. Shaver MD, PhD , Michael A. Matthay MD","doi":"10.1016/j.healun.2025.08.014","DOIUrl":"10.1016/j.healun.2025.08.014","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 12","pages":"Page 2044"},"PeriodicalIF":6.0,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145555096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-21DOI: 10.1016/j.healun.2025.06.027
Shivank Madan MD, MHA , Omar Saeed MD , Daniel J. Goldstein MD , Ulrich P. Jorde MD
{"title":"Navigating increasing donor age and extended preservation times with machine perfusion","authors":"Shivank Madan MD, MHA , Omar Saeed MD , Daniel J. Goldstein MD , Ulrich P. Jorde MD","doi":"10.1016/j.healun.2025.06.027","DOIUrl":"10.1016/j.healun.2025.06.027","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 12","pages":"Pages 2035-2036"},"PeriodicalIF":6.0,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145555097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-21DOI: 10.1016/j.healun.2025.07.027
Yeahwa Hong M.D., Ph.D. , David J. Kaczorowski M.D.
{"title":"Reassessing the impact of ex vivo heart perfusion in donation after brain death heart transplantation","authors":"Yeahwa Hong M.D., Ph.D. , David J. Kaczorowski M.D.","doi":"10.1016/j.healun.2025.07.027","DOIUrl":"10.1016/j.healun.2025.07.027","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 12","pages":"Pages 2037-2039"},"PeriodicalIF":6.0,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145555098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1016/j.healun.2025.10.020
Ioannis Dimarakis MD, PhD , Bassel Al-Alao MBBS , Charlene Tennyson MBBS , Mackenzie Adcox MD , David Edwards , Travis Bourland , Brent Beatty , Alexis Voitik , Bethany Sissom , Mackenzy Keller , Chris Figland , Jessica Gimelli , Peter Wong , Tony Li , Trang Bodtke , April Stempien-Otero MD , Richard K. Cheng MD , Jay D. Pal MD, PhD
Background
Donation after circulatory death (DCD) heart transplantation commonly relies on normothermic regional perfusion or ex vivo reanimation, both of which can be resource-intensive and operationally complex. To simplify procurement and mitigate logistical constraints, a direct procurement strategy employing oxygenated cold blood perfusion without reanimation was introduced. This study describes the early outcomes associated with this simplified technique.
Methods
A streamlined direct procurement protocol was implemented in five DCD heart donors. Hearts were recovered without the use of normothermic regional perfusion and were instead flushed with oxygenated cold blood perfusion followed by a standard preservation solution. Transplantation was performed using conventional implantation methods. Postoperative graft function, rejection events, and early clinical outcomes were assessed during short-term follow-up.
Results
All five transplant procedures were successfully completed. Recipients exhibited normal postoperative graft function with no evidence of rejection during the short-term follow-up period. The simplified procurement method proved feasible, operationally efficient, and less resource-dependent than existing reanimation-based techniques. Early results indicate that this approach may represent a cost-effective alternative for DCD heart recovery and may contribute to expanding the DCD donor pool.
{"title":"Donation after circulatory determination of death heart transplantation using simplified direct procurement: Expanding access","authors":"Ioannis Dimarakis MD, PhD , Bassel Al-Alao MBBS , Charlene Tennyson MBBS , Mackenzie Adcox MD , David Edwards , Travis Bourland , Brent Beatty , Alexis Voitik , Bethany Sissom , Mackenzy Keller , Chris Figland , Jessica Gimelli , Peter Wong , Tony Li , Trang Bodtke , April Stempien-Otero MD , Richard K. Cheng MD , Jay D. Pal MD, PhD","doi":"10.1016/j.healun.2025.10.020","DOIUrl":"10.1016/j.healun.2025.10.020","url":null,"abstract":"<div><h3>Background</h3><div>Donation after circulatory death (DCD) heart transplantation commonly relies on normothermic regional perfusion or ex vivo reanimation, both of which can be resource-intensive and operationally complex. To simplify procurement and mitigate logistical constraints, a direct procurement strategy employing oxygenated cold blood perfusion without reanimation was introduced. This study describes the early outcomes associated with this simplified technique.</div></div><div><h3>Methods</h3><div>A streamlined direct procurement protocol was implemented in five DCD heart donors. Hearts were recovered without the use of normothermic regional perfusion and were instead flushed with oxygenated cold blood perfusion followed by a standard preservation solution. Transplantation was performed using conventional implantation methods. Postoperative graft function, rejection events, and early clinical outcomes were assessed during short-term follow-up.</div></div><div><h3>Results</h3><div>All five transplant procedures were successfully completed. Recipients exhibited normal postoperative graft function with no evidence of rejection during the short-term follow-up period. The simplified procurement method proved feasible, operationally efficient, and less resource-dependent than existing reanimation-based techniques. Early results indicate that this approach may represent a cost-effective alternative for DCD heart recovery and may contribute to expanding the DCD donor pool.</div></div>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 199-203"},"PeriodicalIF":6.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1016/j.healun.2025.10.011
Anthony P. Carnicelli MD , Shashank S. Sinha MD, MSc , Song Li MD , Borui Li MA , Michele Esposito MD , Rachna Kataria MD , Arthur R. Garan MD , Van-Khue Ton MD, PhD , Kevin John MD , Elric Zweck MD , Jaime Hernandez-Montfort MD , Jacob Abraham MD , Daniel Burkhoff MD, PhD , Manreet K. Kanwar MD , Navin K. Kapur MD , On Behalf of the Cardiogenic Shock Working Group Academic Consortium
{"title":"Author’s response to Moeller et al.","authors":"Anthony P. Carnicelli MD , Shashank S. Sinha MD, MSc , Song Li MD , Borui Li MA , Michele Esposito MD , Rachna Kataria MD , Arthur R. Garan MD , Van-Khue Ton MD, PhD , Kevin John MD , Elric Zweck MD , Jaime Hernandez-Montfort MD , Jacob Abraham MD , Daniel Burkhoff MD, PhD , Manreet K. Kanwar MD , Navin K. Kapur MD , On Behalf of the Cardiogenic Shock Working Group Academic Consortium","doi":"10.1016/j.healun.2025.10.011","DOIUrl":"10.1016/j.healun.2025.10.011","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 313-314"},"PeriodicalIF":6.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-13DOI: 10.1016/j.healun.2025.10.025
Maria Francesca Scuppa MD , Guillaume Coutance MD, PhD
{"title":"Not for the faint of heart—and yet: Donation after circulatory death simultaneous heart-kidney transplantation delivers","authors":"Maria Francesca Scuppa MD , Guillaume Coutance MD, PhD","doi":"10.1016/j.healun.2025.10.025","DOIUrl":"10.1016/j.healun.2025.10.025","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 212-214"},"PeriodicalIF":6.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.healun.2025.10.023
Satona Tanaka , Daisuke Nakajima , Hiroshi Date
{"title":"Comments and opinions regarding “International Society for Heart and Lung Transplantation Consensus Statement on the Referral and Selection of Pediatric Lung Transplant Candidates”: Expanding role of living-donor lobar lung transplantation in pediatric patients","authors":"Satona Tanaka , Daisuke Nakajima , Hiroshi Date","doi":"10.1016/j.healun.2025.10.023","DOIUrl":"10.1016/j.healun.2025.10.023","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 315-316"},"PeriodicalIF":6.0,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.healun.2025.10.015
Norihisa Shigemura MD, PhD , Chadi A. Hage MD
{"title":"Beyond the incision: Integrating mechanical circulatory support and less-invasive approaches in lung transplantation","authors":"Norihisa Shigemura MD, PhD , Chadi A. Hage MD","doi":"10.1016/j.healun.2025.10.015","DOIUrl":"10.1016/j.healun.2025.10.015","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 251-252"},"PeriodicalIF":6.0,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145516282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.healun.2025.10.018
John M. Trahanas, Aaron M. Williams
{"title":"Follow the lead of the Valiant − heart transplantation after prolonged donor ischemia time","authors":"John M. Trahanas, Aaron M. Williams","doi":"10.1016/j.healun.2025.10.018","DOIUrl":"10.1016/j.healun.2025.10.018","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Pages 182-183"},"PeriodicalIF":6.0,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145516248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-07DOI: 10.1016/j.healun.2025.10.009
Jennifer K.L. Chow MD, MS, David R. Snydman MD
{"title":"Response to “Letermovir prophylaxis and CMV immune monitoring: Toward a win–win strategy in heart transplantation”","authors":"Jennifer K.L. Chow MD, MS, David R. Snydman MD","doi":"10.1016/j.healun.2025.10.009","DOIUrl":"10.1016/j.healun.2025.10.009","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"45 2","pages":"Page 311"},"PeriodicalIF":6.0,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号