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Climate, conflict, and food security: a systematic review of household-level evidence (2020-2025). 气候、冲突和粮食安全:对家庭层面证据的系统审查(2020-2025年)。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-16 DOI: 10.1186/s41043-026-01267-0
Mahlet Degefu Awoke, Tilman Brück

Climate and conflict crises increasingly occur together, creating compounded risks for household food security. This review synthesizes evidence from 37 quantitative studies published 2020-2025 on how climate crises (such as drought, storms, or floods), violent conflict (such as war and institutional fragility), and their interactions affect household food security. Most studies examine either climate crises (51%) or conflict crises (38%), while only 11% analyze combined crises. Evidence is geographically concentrated in Sub-Saharan Africa (65%) and relies largely on cross-sectional surveys (68%), limiting insight into longer-term trajectories. Climate crises are measured mainly using meteorological or remote-sensing datasets (42%) while conflict exposure relies predominantly on self-reported data (71%). Only a small number of studies integrate geocoded climate or political violence datasets with household surveys, and few studies estimate interaction or spillover effects. Food security measurement is also narrow, with most studies using access and utilization indicators such as the food consumption score (FCS) (43%), household food insecurity access scale (HFIAS) (35%), or household dietary diversity score (HDDS) (19%). Across studies, climate crises, conflict, and their concurrence are associated with reduced consumption, lower dietary diversity, and greater coping burdens. Impacts vary by household assets, agroecology, and institutional or humanitarian support, highlighting the need for longitudinal and spatially or contextually explicit evidence measuring productive resilience rather than only short-term consumption smoothing.

气候危机和冲突危机越来越多地同时发生,给家庭粮食安全带来了复杂的风险。本综述综合了发表于2020-2025年的37项定量研究的证据,这些研究涉及气候危机(如干旱、风暴或洪水)、暴力冲突(如战争和制度脆弱性)及其相互作用如何影响家庭粮食安全。大多数研究要么考察气候危机(51%),要么考察冲突危机(38%),而只有11%的研究分析综合危机。证据在地理上集中在撒哈拉以南非洲(65%),主要依赖于横断面调查(68%),限制了对长期轨迹的了解。测量气候危机主要使用气象或遥感数据集(42%),而冲突暴露主要依赖于自我报告的数据(71%)。只有少数研究将地理编码的气候或政治暴力数据集与家庭调查相结合,很少有研究估计相互作用或溢出效应。粮食安全衡量也很狭隘,大多数研究使用获取和利用指标,如食品消费评分(FCS)(43%)、家庭粮食不安全获取量表(HFIAS)(35%)或家庭饮食多样性评分(hdd)(19%)。研究表明,气候危机、冲突及其并发性与消费减少、饮食多样性降低和应对负担加重有关。影响因家庭资产、生态农业、机构或人道主义支持而异,因此需要纵向、空间或背景上明确的证据来衡量生产复原力,而不仅仅是短期消费平滑。
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引用次数: 0
Nourishing longevity: sustainable healthy eating behaviors and successful aging in community-dwelling older adults, Abha, Saudi Arabia. 营养长寿:可持续的健康饮食行为和社区居住老年人的成功老龄化,阿卜哈,沙特阿拉伯。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-16 DOI: 10.1186/s41043-026-01252-7
Amani Alhazmi, Manal Mohammed Hawash, Farah Aziz, Maha Ali, Mona Metwally El-Sayed, Haroon Ali, Mahmoud Abdelwahab Khader, Sarah Ali Hafez

Background: Successful aging (SA) is a key focus in gerontological research, highlighting the importance of maintaining physical, cognitive, and social well-being. Nutrition is a critical determinant of health in older adults, and sustainable healthy eating behaviors are increasingly recognized for their role in promoting SA and longevity. However, evidence examining this relationship within the Saudi context remains limited.

Aim: This study investigated the relationship between sustainable healthy eating behaviors and successful aging among community-dwelling older adults.

Methods: A cross-sectional study was conducted among 400 community-dwelling older adults aged 60 years and above, recruited from primary health care centers in the Abha district of Saudi Arabia. Data were collected using the Successful Aging Scale (SAS) and the Sustainable and Healthy Eating Behaviors Scale (SHEBS). Spearman's rho correlation and a multivariate general linear model were applied to assess associations and predictors.

Results: The findings showed that sustainable, healthy eating behaviors (SHEB) and SA scores were both relatively high among participants. Primary education, sufficient income, normal BMI, and favorable lifestyle factors emerged as significant predictors for both SHEB and SA.

Conclusion: The study shows that SHEB emerged as a significant predictor of SA. In addition to dietary practices, sociodemographic factors, physical activity, and sleep quality contributed significantly to SA outcomes. These findings underscore the need for culturally tailored strategies that support sustainable nutrition and promote healthy lifestyle behaviors among older adults in Saudi Arabia, thereby supporting SA.

背景:成功衰老(SA)是老年学研究的一个重点,强调了保持身体、认知和社会健康的重要性。营养是老年人健康的关键决定因素,可持续的健康饮食行为在促进SA和长寿方面的作用越来越被认识到。然而,在沙特背景下检验这种关系的证据仍然有限。目的:探讨社区居住老年人持续健康饮食行为与成功老龄化的关系。方法:从沙特阿拉伯Abha地区的初级卫生保健中心招募400名60岁及以上的社区老年人进行横断面研究。采用成功老龄化量表(SAS)和可持续健康饮食行为量表(SHEBS)收集数据。Spearman’s rho相关和多元一般线性模型被用于评估关联和预测因子。结果:研究结果显示,参与者的可持续健康饮食行为(SHEB)和SA得分均较高。小学教育、足够的收入、正常的BMI和良好的生活方式因素是SHEB和SA的重要预测因素。结论:研究表明SHEB是SA的重要预测因子。除了饮食习惯外,社会人口因素、身体活动和睡眠质量对SA的结果也有显著影响。这些发现强调有必要制定适合文化的战略,以支持沙特阿拉伯老年人的可持续营养和促进健康的生活方式行为,从而支持SA。
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引用次数: 0
Association of dietary protein and amino acid intakes with all-cause disability-adjusted life years: cross-sectional analysis of the national health and nutrition survey in Japan. 膳食蛋白质和氨基酸摄入量与全因残疾调整寿命年的关系:日本全国健康和营养调查的横断面分析。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-16 DOI: 10.1186/s41043-026-01264-3
Kazuko Ishikawa-Takata, Kazuki Fujiwara, Takayuki Tanaka, Keiji Nakamura, Hisamine Kobayashi, Shinobu Okada

Background: Extension of healthy longevity is an important health program in long-lived countries like Japan. The Dietary Reference Intakes for Japanese 2025 established tentative dietary goals for the prevention of lifestyle-related diseases; however, the adequate macronutrient energy ratios in a diet to support longevity remain unclear, particularly for the protein content. This study aimed to evaluate the associations between protein or amino acid intakes and healthy aging in the Japanese population.

Methods: Global Burden of Disease Study data and de-identified individual records in the National Health and Nutrition Survey Japan from 2001 to 2019 for subjects aged ≥ 20 years were used. Multiple regression analyses were conducted to assess the relationships between all-cause disability-adjusted life years (DALYs) as an index for healthy aging and protein or amino acid intakes, with adjustment for lifestyle factors and sociodemographic index as confounding factors.

Results: The mean DALYs (per 100,000 people) were 10287.91 for women and 12566.85 for men. Women exhibited no significant correlations between protein or amino acid intakes and DALYs. In men, significant negative correlations were observed for plant protein (partial regression coefficient [Coeff.] - 6063.267; p = 0.010), cysteine (Coeff. -127.575; p = 0.044), phenylalanine (Coeff. -38.506; p = 0.048), glutamic acid (Coeff. -12.184; p = 0.006), and proline (Coeff. -31.499; p = 0.010) intakes with DALYs after adjustment for sociodemographic index, drinking habit, smoking habit, and exercise habit.

Conclusions: Higher intakes of plant protein, cysteine, phenylalanine, glutamic acid, and proline were correlated with lower DALYs in men only. Adequate plant protein and specific amino acid intakes may be related to the extension of healthy life expectancy.

背景:延长健康寿命是日本等长寿国家的一项重要健康计划。《日本2025年膳食参考摄入量》为预防与生活方式有关的疾病确立了暂定膳食目标;然而,饮食中支持长寿的足够的常量营养素能量比例仍不清楚,特别是蛋白质含量。本研究旨在评估日本人群中蛋白质或氨基酸摄入量与健康老龄化之间的关系。方法:使用2001年至2019年日本国民健康与营养调查中年龄≥20岁的全球疾病负担研究数据和未识别的个人记录。采用多元回归分析评估作为健康老龄化指标的全因残疾调整生命年(DALYs)与蛋白质或氨基酸摄入量之间的关系,并将生活方式因素和社会人口指数作为混杂因素进行调整。结果:平均DALYs(每10万人)女性为10287.91,男性为12566.85。女性在蛋白质或氨基酸摄入量与DALYs之间没有明显的相关性。在男性中,植物蛋白(偏回归系数[Coeff.] - 6063.267; p = 0.010)和半胱氨酸(Coeff.)呈显著负相关。-127.575;p = 0.044),苯丙氨酸(Coeff;-38.506;p = 0.048),谷氨酸(Coeff;-12.184;p = 0.006),脯氨酸(Coeff;-31.499;p = 0.010),在调整社会人口指数、饮酒习惯、吸烟习惯和运动习惯后,摄入量与DALYs。结论:仅在男性中,较高的植物蛋白、半胱氨酸、苯丙氨酸、谷氨酸和脯氨酸摄入量与较低的DALYs相关。充足的植物蛋白和特定氨基酸的摄入可能与健康预期寿命的延长有关。
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引用次数: 0
"My home garden is a peace maker": perceived impact pathways of a home gardening intervention in rural Kenya: the ALIMUS study. “我的家庭花园是一个和平的制造者”:在肯尼亚农村家庭园艺干预的感知影响途径:ALIMUS研究。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-15 DOI: 10.1186/s41043-026-01263-4
Erick Agure, Grace Wothaya Kihagi, Erick M O Muok, Raissa Sorgho, Ina Danquah

Background: Home gardens are promoted as a strategy for climate change adaptation in SSA. Here, we determined the lived experiences, the perceived knowledge gain and practice change, and the suggested strategies for maintenance, spread and scaling among beneficiaries, implementers and stakeholders of a home gardening intervention in rural Kenya.

Methods: For this explanatory qualitative study, we conducted two focus group discussions (FGDs) with stakeholders (n = 5) and implementers (n = 8), and 30 in-depth interviews (IDIs) with male (n = 5) and female (n = 25) beneficiaries living in Siaya county, from September to November 2023. We used purposive sampling and employed semi-structured interview guides. The data were translated into English, transcribed verbatim, and analyzed using inductive content analysis; we mapped the findings along the proposed impact pathways.

Results: The participants articulated good understanding of the trainings and valued them as an occasion for knowledge exchange. The adoption of tailored garden structures, organic gardening, and food preservation created feelings of fulfillment, women empowerment, and family peace. Experienced challenges included water scarcity, ineffective pesticides, and long distances between the beneficiary households. Perceived benefits were increased income, cost savings, and increased dietary diversity. For maintenance, spread and scale, the participants suggested agri-business, local partnerships, and the integration of home gardens into the county's political agenda.

Conclusions: This project seems to have followed its planned pathways to improved child nutritional status. The organic gardening approach offers solutions in low-resource settings but creates challenges for maintenance, spread and scale of home gardens in Siaya county, Kenya.

背景:家庭花园作为一种适应气候变化的策略在SSA得到推广。在这里,我们确定了肯尼亚农村家庭园艺干预的生活经验、感知到的知识获取和实践变化,以及建议的维护、传播和扩展策略,受益者、实施者和利益相关者。方法:为了进行解释性定性研究,我们于2023年9月至11月与利益相关者(n = 5)和执行者(n = 8)进行了两次焦点小组讨论(fgd),并对居住在西亚县的男性(n = 5)和女性(n = 25)受益人进行了30次深度访谈(IDIs)。我们采用目的性抽样和半结构化访谈指南。将资料翻译成英文,逐字抄录,采用归纳内容分析法进行分析;我们沿着建议的影响路径绘制了研究结果。结果:参与者对培训表达了良好的理解,并将其视为知识交流的机会。采用量身定制的花园结构,有机园艺和食品保存创造了满足感,妇女赋权和家庭和平。经历过的挑战包括缺水、杀虫剂无效以及受益家庭之间距离遥远。预期的好处是增加了收入,节约了成本,增加了饮食的多样性。在维护、传播和规模方面,与会者建议农业企业、当地合作伙伴关系以及将家庭花园纳入国家政治议程。结论:该项目似乎已按计划改善了儿童营养状况。在肯尼亚Siaya县,有机园艺方法为资源匮乏的环境提供了解决方案,但也为家庭花园的维护、传播和规模带来了挑战。
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引用次数: 0
Prolonged breastfeeding and hypertension risk among Kenyan women: exploring the roles of obesity and alcohol consumption. 肯尼亚妇女长期母乳喂养和高血压风险:探讨肥胖和饮酒的作用。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-15 DOI: 10.1186/s41043-026-01272-3
Joshua Okyere, Castro Ayebeng, Kwamena Sekyi Dickson, Stephen Ombija, Precious Adade Duodu

Background: Breastfeeding is known to have positive effects on child health outcomes. However, little is known about its effects on physical health outcomes for mothers. Given that hypertension remains a significant public health concern in Kenya, it is imperative to understand whether breastfeeding has some protective effects for mothers. This study investigates the association between breastfeeding duration and hypertension risk while considering the moderating effects of overweight/obesity and alcohol consumption.

Methods: We relied on 2022 Kenya demographic and health survey data. A total sample of 5314 was analyzed. Prevalence rates of hypertension were assessed across different breastfeeding durations, and both unadjusted and adjusted odds ratios were calculated to evaluate the risk of hypertension. Interaction effects between breastfeeding duration, overweight/obesity status, and alcohol consumption were also analyzed with predictive margins.

Results: Overall, the prevalence of hypertension in the sample was 8.7% (95% CI: 7.7-9.9). After adjusting for confounders, women who breastfed for 12-24 months (AOR = 0.60, 95%CI: 0.43-0.84) and for more than 24 months (AOR = 0.60, 95%CI: 0.45-0.80) were at lower odds of being hypertensive. Despite the increased risk of hypertension among overweight or obese women and those who consumed alcohol, the predictive margins did not show a significant moderating effect of these factors on the association between breastfeeding duration and hypertension in this study.

Conclusion: Our study suggests that prolonged breastfeeding may have a protective effect against hypertension among parous women. This protective effect of longer breastfeeding durations remains relatively stable across different obesity and alcohol consumption statuses. It is essential for the Kenyan Ministry of Health to intensify its breastfeeding awareness. Health providers at antenatal and postnatal care centers must emphasize the protective effects of prolonged breastfeeding on physical health outcomes.

背景:众所周知,母乳喂养对儿童健康结果有积极影响。然而,人们对它对母亲身体健康结果的影响知之甚少。鉴于高血压在肯尼亚仍然是一个重大的公共卫生问题,必须了解母乳喂养是否对母亲有一定的保护作用。本研究调查了母乳喂养时间与高血压风险之间的关系,同时考虑了超重/肥胖和饮酒的调节作用。方法:利用2022年肯尼亚人口与健康调查数据。共分析了5314份样本。评估不同母乳喂养持续时间的高血压患病率,并计算未调整和调整的优势比,以评估高血压的风险。母乳喂养持续时间、超重/肥胖状况和饮酒之间的相互作用也进行了预测边际分析。结果:总体而言,样本中高血压患病率为8.7% (95% CI: 7.7-9.9)。在调整混杂因素后,母乳喂养12-24个月(AOR = 0.60, 95%CI: 0.43-0.84)和超过24个月(AOR = 0.60, 95%CI: 0.45-0.80)的妇女患高血压的几率较低。尽管超重或肥胖妇女和饮酒妇女患高血压的风险增加,但在本研究中,这些因素在母乳喂养时间和高血压之间的关系中没有显示出显著的调节作用。结论:我们的研究表明,延长母乳喂养可能对分娩妇女的高血压有保护作用。较长的母乳喂养持续时间的这种保护作用在不同的肥胖和饮酒状态下保持相对稳定。肯尼亚卫生部必须加强对母乳喂养的认识。产前和产后护理中心的保健提供者必须强调长期母乳喂养对身体健康结果的保护作用。
{"title":"Prolonged breastfeeding and hypertension risk among Kenyan women: exploring the roles of obesity and alcohol consumption.","authors":"Joshua Okyere, Castro Ayebeng, Kwamena Sekyi Dickson, Stephen Ombija, Precious Adade Duodu","doi":"10.1186/s41043-026-01272-3","DOIUrl":"10.1186/s41043-026-01272-3","url":null,"abstract":"<p><strong>Background: </strong>Breastfeeding is known to have positive effects on child health outcomes. However, little is known about its effects on physical health outcomes for mothers. Given that hypertension remains a significant public health concern in Kenya, it is imperative to understand whether breastfeeding has some protective effects for mothers. This study investigates the association between breastfeeding duration and hypertension risk while considering the moderating effects of overweight/obesity and alcohol consumption.</p><p><strong>Methods: </strong>We relied on 2022 Kenya demographic and health survey data. A total sample of 5314 was analyzed. Prevalence rates of hypertension were assessed across different breastfeeding durations, and both unadjusted and adjusted odds ratios were calculated to evaluate the risk of hypertension. Interaction effects between breastfeeding duration, overweight/obesity status, and alcohol consumption were also analyzed with predictive margins.</p><p><strong>Results: </strong>Overall, the prevalence of hypertension in the sample was 8.7% (95% CI: 7.7-9.9). After adjusting for confounders, women who breastfed for 12-24 months (AOR = 0.60, 95%CI: 0.43-0.84) and for more than 24 months (AOR = 0.60, 95%CI: 0.45-0.80) were at lower odds of being hypertensive. Despite the increased risk of hypertension among overweight or obese women and those who consumed alcohol, the predictive margins did not show a significant moderating effect of these factors on the association between breastfeeding duration and hypertension in this study.</p><p><strong>Conclusion: </strong>Our study suggests that prolonged breastfeeding may have a protective effect against hypertension among parous women. This protective effect of longer breastfeeding durations remains relatively stable across different obesity and alcohol consumption statuses. It is essential for the Kenyan Ministry of Health to intensify its breastfeeding awareness. Health providers at antenatal and postnatal care centers must emphasize the protective effects of prolonged breastfeeding on physical health outcomes.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"69"},"PeriodicalIF":2.8,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12918263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional status of children under-five in rural mozambique: the role of phytate intake and mineral bioavailability. 莫桑比克农村五岁以下儿童的营养状况:植酸盐摄入量和矿物质生物利用度的作用。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-14 DOI: 10.1186/s41043-026-01247-4
Ieva Sateikaite, Yasaman Samaei, Maida Khan, Irene Carvalho, Claudia E Lazarte

Background: Globally, undernutrition is responsible for over 3.5 million deaths among children under the age of 5. In Mozambique, it remains a major contributing factor to the high rates of child mortality and illness. Essential micronutrients like zinc, iron, and calcium play a vital role in healthy growth and development. However, their absorption is hindered by anti-nutrients such as phytates, which chelate these minerals and reduce their bioavailability. The extent of this inhibitory effect largely depends on the molar ratios of phytate to the respective minerals.

Objective: To assess the dietary patterns and quality of diets consumed by young children; with a primary focus on micronutrients adequacy, phytate intake and the implications on mineral bioavailability.

Methods: Anthropometric measurements and dietary assessment of 47 children, aged 2 to 5 years, accompanied by their mothers. The method Food Photography 24-h Recall (FP24hR) was used for three consecutive days to evaluate their nutrient intake, which included macronutrients, 15 micronutrients and phytate intake. The estimated mineral bioavailability of the diets was determined based on the phytate-to-mineral molar ratios.

Results: Stunting was found in 32% of children and waste in 6% of them, 2% of children were underweight, and 13% were overweight. Children were found to be at risk of calcium, zinc, vitamins A, E, B12 and folate deficiencies. The molar ratio phytate-to-Zinc (phy:Zn) was between 22.3 and 31.2; phytate-to-Iron (phy:Fe) was between 7.2 and 16.3 and phytate-to-Calcium (phy:Ca) was between 0.34 and 0.53. All the ratios exceeded the recommended values phy:Zn < 15, phy:Fe < 1, and phy:Ca < 0.24, which indicates that phytate in the children's diet can negatively affect the bioavailability of zinc, iron and calcium.

Conclusion: The high prevalence of stunting among children in this study highlights a persistent issue of chronic undernutrition in the region. The elevated phytate-to-mineral molar ratios suggest a reduced mineral absorption, which is a contributing factor to growth failure in children. These findings underscore the urgent need for targeted nutrition policies in Mozambique to address both dietary quality and phytate content.

背景:在全球范围内,营养不良是造成350多万5岁以下儿童死亡的原因。在莫桑比克,它仍然是造成儿童死亡率和发病率高的一个主要因素。锌、铁和钙等必需微量元素对健康生长发育起着至关重要的作用。然而,它们的吸收受到植酸盐等抗营养素的阻碍,这些营养素会螯合这些矿物质并降低它们的生物利用度。这种抑制作用的程度在很大程度上取决于植酸与相应矿物质的摩尔比。目的:了解幼儿膳食结构及膳食质量;主要关注微量营养素的充足性、植酸盐的摄入以及对矿物质生物利用度的影响。方法:对47例2 ~ 5岁儿童在母亲陪同下进行人体测量和饮食评价。采用食品摄影24小时召回法(Food Photography 24-h Recall, FP24hR)连续3天评估其营养摄入量,包括常量营养素、15种微量营养素和植酸盐摄入量。根据植酸与矿物质摩尔比确定饲粮中估计的矿物质生物利用度。结果:32%的儿童发育迟缓,6%的儿童消瘦,2%的儿童体重不足,13%的儿童超重。研究发现,儿童存在钙、锌、维生素A、E、B12和叶酸缺乏的风险。植酸与锌的摩尔比(phy:Zn)为22.3 ~ 31.2;植酸对铁的比值(phy:Fe)为7.2 ~ 16.3,植酸对钙的比值(phy:Ca)为0.34 ~ 0.53。结论:本研究中儿童发育迟缓的高发突出了该地区长期存在的慢性营养不良问题。升高的植酸与矿物质摩尔比表明矿物质吸收减少,这是导致儿童生长衰竭的一个因素。这些发现强调了莫桑比克迫切需要制定有针对性的营养政策,以解决膳食质量和植酸含量问题。
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引用次数: 0
Caffeic acid for the management of leukopenia: a systematic review and meta-analysis. 咖啡酸治疗白细胞减少症:一项系统综述和荟萃分析。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-14 DOI: 10.1186/s41043-025-01197-3
Feng Dai, Yingjian Wang, Mengsi Hu, Yanzhong Wang, Yirui Chen, Zhiwei Liu

Background: Many randomized controlled trials (RCTs) have revealed the benefits of caffeic acid tablets on leukopenia and thrombocytopenia, but the results are inconclusive. This meta-analysis of RCTs aimed to assess the effects of caffeic acid tablet supplementation on treating leukopenia.

Methods: A systematic review of PubMed, Scopus, Embase, Cochrane library, China Knowledge Network, China Biomedical Literature Database, Wipu.com and Wanfang Data were conducted, and the search time frame was from the establishment of the database up to May 2025. Data were pooled using a random-effects model to calculate standardized mean differences (SMDs) and 95% confidence intervals (CIs).

Results: Thirty-three studies with 2,483 patients were included. Meta-analysis results indicated that the clinical effectiveness of caffeic acid tablets for leukopenia was significantly different from that of the control group (RR: 1.44; 95% CI: 1.31, 1.58, p < 0.01; I2 = 67.0%, p < 0.01), and significantly increased white blood cell count (SMD: 1.39, 95% CI: 1.09, 1.70, p < 0.001; I2 = 85.4%, p < 0.001), platelet count (SMD: 1.18, 95% CI: 0.46, 1.89, p < 0.001; I2 = 94.4%, p < 0.001), and neutrophil count (SMD:0.88, 95% CI: 0.60, 1.16, p < 0.001; I2 = 49.0%, p = 0.081). Caffeic acid tablets can reduce bone marrow suppression (RR: 0.34; 95% CI: 0.22, 0.54, p < 0.001; I2 = 0.0%, p = 0.685), incidence of infection (RR: 0.50; 95% CI: 0.38, 0.64, p < 0.001; I2 = 0.0%, p = 0.833) was significantly lower than that of the control group.

Conclusion: Caffeic acid may be a promising management for the treatment of leukopenia. The findings should be interpreted with caution due to the high risk of bias in many included trials and the limited generalizability, as all studies were conducted in China.

背景:许多随机对照试验(rct)已经揭示了咖啡酸片对白细胞减少和血小板减少的益处,但结果尚无定论。本荟萃分析旨在评估补充咖啡酸片治疗白细胞减少症的效果。方法:对PubMed、Scopus、Embase、Cochrane图书馆、中国知识网、中国生物医学文献数据库、Wipu.com和万方数据进行系统综述,检索时间范围为建库至2025年5月。使用随机效应模型合并数据,计算标准化平均差(SMDs)和95%置信区间(ci)。结果:纳入33项研究,2483例患者。荟萃分析结果显示,咖啡酸片治疗白细胞减少症的临床疗效与对照组有显著差异(RR: 1.44; 95% CI: 1.31, 1.58, p = 67.0%, p = 85.4%, p = 94.4%, p = 49.0%, p = 0.081)。咖啡酸片可减轻骨髓抑制(RR: 0.34; 95% CI: 0.22, 0.54, p = 0.0%, p = 0.685),感染发生率(RR: 0.50; 95% CI: 0.38, 0.64, p 2 = 0.0%, p = 0.833)显著低于对照组。结论:咖啡酸可能是治疗白细胞减少症的有效方法。由于所有研究都是在中国进行的,因此许多纳入的试验存在高偏倚风险,而且推广能力有限,因此应谨慎解释这些发现。
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引用次数: 0
Effect of the healthy school recognized campus initiative on metabolic syndrome among adolescents in texas: a pilot randomized factorial trial study. 健康学校认可的校园倡议对德克萨斯州青少年代谢综合征的影响:一项随机因子试验研究。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-14 DOI: 10.1186/s41043-026-01261-6
Mia H Putnam, Gabrielli T de Mello, Julie Gardner, Alexandra L MacMillan Uribe, Chad D Rethorst, Allyson Schaefers, Rebecca A Seguin-Fowler, Ryan W Walters, Jacob Szeszulski

Background: School-based interventions are effective in improving physical activity and healthy eating in adolescents. However, there has been limited research into how bundled school-based programs, and their components, may improve adolescents' metabolic health. The purpose of this study is to evaluate the effectiveness of the Healthy School Recognized Campus (HSRC) - a bundled school-based health initiative - and two HSRC components on metabolic syndrome (MetS) and other obesity-related risk factors.

Methods: A 2 × 2 cluster randomized factorial trial was conducted in eight HSRC middle schools (n = 107 students) to pilot test a novel program's (Strong Teens for Healthy Schools [STHS]) and implementation strategy's (mentoring program) preliminary effects on MetS z-scores, obesity-related risk factors (e.g., BMI z-scores), and behavioral risk factors (e.g., physical activity, healthy eating). General linear model frameworks were used to estimate the main and interaction effects on outcomes. Additionally, bivariate tests were run to determine if students had a significant change in outcomes over the year-long HSRC intervention.

Results: Across all schools, students involved in the HSRC program decreased BMI z-scores (mean difference [MD]=-0.12 ± 0.33, p=.003); whereas students increased glucose levels (MD = 6.29 ± 18.34, p=.003), total MetS factors (MD = 0.23 ± 0.83, p=.015), and fruit and vegetable consumption (MD = 34.47 ± 92.33, p = < 0.001). The STHS intervention was associated with an increase in waist circumference (β = 5.55, 95%CI: 0.14, 10.96, p=.044). The mentoring program was associated with a reduction in systolic blood pressure (β=-6.32, 95%CI: -12.13, -0.51, p=.033) and increase in dermal carotenoids (β = 65.50, 95%CI: 18.11, 112.89, p=.007).

Conclusions: HSRC improved some obesity-related risk factors, but not MetS severity. The STHS intervention independently increased waist circumference, and the mentoring program independently improved dermal carotenoid levels and systolic blood pressure. Results suggest that complex interaction effects exist in bundled interventions within school settings; however, bundled EBPs may be effective in reducing some obesity-related outcomes (e.g., BMI z-scores) over a one-year duration for adolescents in East Texas.

背景:以学校为基础的干预措施在改善青少年的身体活动和健康饮食方面是有效的。然而,关于如何将基于学校的项目及其组成部分捆绑起来改善青少年代谢健康的研究有限。本研究的目的是评估健康学校认可校园(HSRC)的有效性,这是一项基于学校的捆绑健康倡议,以及两个HSRC组件对代谢综合征(MetS)和其他肥胖相关风险因素的影响。方法:在8所HSRC中学(n = 107名学生)进行2 × 2聚类随机因子试验,初步检验新项目(健康学校强青少年项目[STHS])和实施策略(指导项目)对MetS z-score、肥胖相关危险因素(如BMI z-score)和行为危险因素(如体育活动、健康饮食)的影响。一般线性模型框架用于估计对结果的主要影响和交互影响。此外,进行双变量测试以确定学生在一年的HSRC干预中是否有显著的结果变化。结果:在所有学校中,参与HSRC项目的学生BMI z-score下降(平均差异[MD]=-0.12±0.33,p= 0.003);而学生的血糖水平(MD = 6.29±18.34,p= 0.003)、总代谢因子(MD = 0.23±0.83,p= 0.015)和水果和蔬菜摄入量(MD = 34.47±92.33,p=结论:HSRC改善了一些肥胖相关的危险因素,但没有改善代谢严重程度。STHS干预独立增加了腰围,指导计划独立改善了皮肤类胡萝卜素水平和收缩压。结果表明,在学校环境中,捆绑干预存在复杂的相互作用效应;然而,在东德克萨斯州的青少年中,捆绑ebp可能在一年的时间内有效地降低一些与肥胖相关的结果(例如,BMI z分数)。
{"title":"Effect of the healthy school recognized campus initiative on metabolic syndrome among adolescents in texas: a pilot randomized factorial trial study.","authors":"Mia H Putnam, Gabrielli T de Mello, Julie Gardner, Alexandra L MacMillan Uribe, Chad D Rethorst, Allyson Schaefers, Rebecca A Seguin-Fowler, Ryan W Walters, Jacob Szeszulski","doi":"10.1186/s41043-026-01261-6","DOIUrl":"10.1186/s41043-026-01261-6","url":null,"abstract":"<p><strong>Background: </strong>School-based interventions are effective in improving physical activity and healthy eating in adolescents. However, there has been limited research into how bundled school-based programs, and their components, may improve adolescents' metabolic health. The purpose of this study is to evaluate the effectiveness of the Healthy School Recognized Campus (HSRC) - a bundled school-based health initiative - and two HSRC components on metabolic syndrome (MetS) and other obesity-related risk factors.</p><p><strong>Methods: </strong>A 2 × 2 cluster randomized factorial trial was conducted in eight HSRC middle schools (n = 107 students) to pilot test a novel program's (Strong Teens for Healthy Schools [STHS]) and implementation strategy's (mentoring program) preliminary effects on MetS z-scores, obesity-related risk factors (e.g., BMI z-scores), and behavioral risk factors (e.g., physical activity, healthy eating). General linear model frameworks were used to estimate the main and interaction effects on outcomes. Additionally, bivariate tests were run to determine if students had a significant change in outcomes over the year-long HSRC intervention.</p><p><strong>Results: </strong>Across all schools, students involved in the HSRC program decreased BMI z-scores (mean difference [MD]=-0.12 ± 0.33, p=.003); whereas students increased glucose levels (MD = 6.29 ± 18.34, p=.003), total MetS factors (MD = 0.23 ± 0.83, p=.015), and fruit and vegetable consumption (MD = 34.47 ± 92.33, p = < 0.001). The STHS intervention was associated with an increase in waist circumference (β = 5.55, 95%CI: 0.14, 10.96, p=.044). The mentoring program was associated with a reduction in systolic blood pressure (β=-6.32, 95%CI: -12.13, -0.51, p=.033) and increase in dermal carotenoids (β = 65.50, 95%CI: 18.11, 112.89, p=.007).</p><p><strong>Conclusions: </strong>HSRC improved some obesity-related risk factors, but not MetS severity. The STHS intervention independently increased waist circumference, and the mentoring program independently improved dermal carotenoid levels and systolic blood pressure. Results suggest that complex interaction effects exist in bundled interventions within school settings; however, bundled EBPs may be effective in reducing some obesity-related outcomes (e.g., BMI z-scores) over a one-year duration for adolescents in East Texas.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13011626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146197769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping inequities in safe water access: a spatial and geographically weighted regression analysis of unimproved water source use in sub-Saharan Africa. 绘制安全用水获取方面的不平等:撒哈拉以南非洲未改善水源使用的空间和地理加权回归分析。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-14 DOI: 10.1186/s41043-026-01259-0
Gelila Yitageasu, Alemayehu Kasu Gebrehana, Angwach Abrham Asnake, Bizunesh Fantahun Kase, Mitkie Tigabie, Lidetu Demoze

Background: Access to safe drinking water remains a major challenge in sub-Saharan Africa, where reliance on unimproved water sources exposes millions to waterborne diseases and undermines progress toward Sustainable Development Goal 6 (SDG 6). Understanding spatial patterns and determinants of unimproved water use is essential for targeting WASH interventions.

Method: We analyzed data from 500,845 households across 20,492 clusters in 34 sub-Saharan African countries using Demographic and Health Surveys (2012-2024). Data was processed using Microsoft Excel and STATA version 17. Prevalence estimates accounted for the DHS complex sampling design. Spatial analyses (Global Moran's I, Getis-Ord Gi*, SaTScan™, Anselin Local Moran's I) and Geographically Weighted Regression (GWR) were conducted to identify clusters and key predictors.

Result: Overall, 58% (95% CI: 51%-65%) of households relied on unimproved drinking water sources. This indicates that approximately three in five households utilize unimproved water source. Significant spatial clustering was detected (Global Moran's I = 0.2415, p < 0.001), with major hotspots in Madagascar, Uganda, Rwanda, Mozambique, Malawi, Chad, Nigeria, Togo, Burkina Faso, Liberia, Sierra Leone, Mali, Ethiopia, parts of Angola, the Congo Republic, Zambia, and Zimbabwe. SaTScan™ identified 109 significant clusters, and Local Moran's I revealed mixed high- and low-risk zones. GWR (adjusted R² = 0.917) highlighted key predictors: rural residence, female-headed households, older household heads (50 + years), poverty, limited media exposure, lack of electricity, and poor water access.

Conclusion: Unimproved water use remains widespread and spatially concentrated across sub-Saharan Africa. The determinants identified by GWR poverty, rural residence, limited infrastructure access, and low household media exposure highlight critical inequities driving this burden. Addressing these disparities requires localized, data-driven WASH planning that prioritizes hotspot regions, expands access to affordable improved water systems, strengthens electricity and media outreach infrastructure, and supports vulnerable households. Implementing these targeted and multi-sectoral strategies is essential for accelerating equitable progress toward SDG 6 and improving public health resilience across the region.

背景:在撒哈拉以南非洲,获得安全饮用水仍然是一项重大挑战,对未经改善的水源的依赖使数百万人面临水传播疾病,并破坏了在实现可持续发展目标6方面取得的进展。了解未改善用水的空间格局和决定因素对于有针对性地采取讲卫生行动至关重要。方法:我们使用人口与健康调查(2012-2024)分析了34个撒哈拉以南非洲国家20,492个集群的500,845个家庭的数据。数据处理采用Microsoft Excel和STATA version 17。流行率估计解释了国土安全部复杂的抽样设计。通过空间分析(Global Moran’s I、Getis-Ord Gi*、SaTScan™、Anselin Local Moran’s I)和地理加权回归(GWR)来识别聚类和关键预测因子。结果:总体而言,58%(95%置信区间:51%-65%)的家庭依赖未经改善的饮用水源。这表明大约五分之三的家庭使用未经改善的水源。全球Moran’s I = 0.2415, p。结论:在撒哈拉以南非洲地区,未经改善的水资源利用仍然普遍存在,并且在空间上集中。GWR贫困、农村居住、基础设施接入有限以及家庭媒体曝光率低等决定因素凸显了造成这一负担的关键不平等现象。解决这些差异需要本地化的、以数据为导向的WASH规划,优先考虑热点地区,扩大可负担得起的改善供水系统,加强电力和媒体宣传基础设施,并为弱势家庭提供支持。实施这些有针对性的多部门战略对于加快实现可持续发展目标6的公平进展和提高整个区域的公共卫生复原力至关重要。
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引用次数: 0
Socio-demographic and economic factors associated with unhealthy food consumption among women of reproductive age in Tanzania: a nationwide cross-sectional study. 与坦桑尼亚育龄妇女不健康食品消费有关的社会人口和经济因素:一项全国性横断面研究。
IF 2.8 3区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-13 DOI: 10.1186/s41043-026-01260-7
Jovinary Adam, Tunu Zablon, Siri Abihudi, Pankras Luoga, Tumaini Nyamhanga

Introduction: The rising consumption of unhealthy foods, characterized by high levels of sugar, salt, and unhealthy fats, poses significant health risks to women. Urbanization and globalization have shifted dietary patterns, leading many people to opt for processed and fast foods over traditional, nutrient-rich meals. This trend contributes to increased rates of non-communicable diseases, such as diabetes, and cardiovascular conditions, particularly among women of reproductive age.

Objective: To determine the socio-demographic and economic factors associated with unhealthy food consumption among women of reproductive age in Tanzania.

Methods: The study analyzed secondary data from the 2022 Tanzania Demographic and Health Survey and Malaria Indicator Survey. The study included a weighted sample of 15,254 women of reproductive age. The "svy" command in Stata was used to assign the sample weight. Multivariable logistic regression was employed to identify significant factors associated with unhealthy food consumption, with significance set at a 5% level.

Results: The overall unhealthy food consumption among women of reproductive was 14% (95% CI: 12.9, 15.2). The study found that women residing in urban areas (AOR = 1.37, 95% CI = 1.17, 1.61), women with secondary education (AOR = 1.72, 95% CI = 1.36, 2.17), higher education (AOR = 2.39, 95% CI = 1.73, 3.31), women from middle quintile (AOR = 1.35, 95% CI = 1.06, 1.73), and rich quintile (AOR = 2.42, 95% CI = 1.92, 3.05), married women (AOR = 0.87, 95% CI = 0.75, 1.00), women who listened to radio (AOR = 1.18, 95% CI = 1.04, 1.34), watching television (AOR = 1.23, 95% CI = 1.08, 1.40), having 0-2 children (AOR = 1.30, 95% CI = 1.06, 1.58) were significantly associated with unhealthy food consumption.

Conclusion: The study found that overall unhealthy food consumption among women of reproductive age was 14%. This was associated with place of residence, education level, wealth status, listening to radio, watching television and number of children. The study recommends implementation of community-based nutritional education programs focusing on healthy eating habits, particularly targeting urban areas where unhealthy food consumption is higher as well as utilize mass media platforms to disseminate information about healthy dietary habits.

引言:以高糖、高盐和高脂肪为特征的不健康食品的消费不断增加,对妇女的健康构成重大风险。城市化和全球化已经改变了饮食模式,导致许多人选择加工食品和快餐,而不是传统的营养丰富的食物。这一趋势导致非传染性疾病,如糖尿病和心血管疾病的发病率上升,特别是在育龄妇女中。目的:确定与坦桑尼亚育龄妇女不健康食品消费相关的社会人口和经济因素。方法:研究分析了2022年坦桑尼亚人口与健康调查和疟疾指标调查的二次数据。该研究包括15254名育龄妇女的加权样本。使用Stata中的“svy”命令来分配样本权重。采用多变量logistic回归确定与不健康食品消费相关的显著因素,显著性设置为5%水平。结果:育龄妇女总体不健康食品消费占14% (95% CI: 12.9, 15.2)。研究发现,女性居住在城市地区(AOR = 1.37, 95% CI = 1.17, 1.61),中等教育的女性(AOR = 1.72, 95% CI = 1.36, 2.17),高等教育(AOR = 2.39, 95% CI = 1.73, 3.31),女性从中间五分位数(AOR = 1.35, 95% CI = 1.06, 1.73),和丰富的五分位数(AOR = 2.42, 95% CI = 1.92, 3.05),已婚妇女(AOR = 0.87, 95% CI = 0.75, 1.00),女性听收音机(AOR = 1.18, 95% CI = 1.04, 1.34),看电视(优势比= 1.23,95% CI = 1.08, 1.40),有0-2个孩子(AOR = 1.30, 95% CI = 1.06, 1.58)与不健康食品消费显著相关。结论:研究发现,育龄妇女不健康食品的总体消费量为14%。这与居住地、教育水平、财富状况、听广播、看电视和孩子的数量有关。该研究建议实施以社区为基础的营养教育计划,重点关注健康的饮食习惯,特别是针对不健康食品消费较高的城市地区,并利用大众媒体平台传播有关健康饮食习惯的信息。
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引用次数: 0
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